2023 Q1 Form 10-K Financial Statement
#000156459023004830 Filed on March 30, 2023
Income Statement
Concept | 2023 Q1 | 2022 Q4 | 2022 |
---|---|---|---|
Revenue | $0.00 | $0.00 | $794.0K |
YoY Change | -100.0% | -100.0% | -89.12% |
Cost Of Revenue | $0.00 | $0.00 | $798.0K |
YoY Change | -100.0% | -100.0% | -89.19% |
Gross Profit | $0.00 | $0.00 | -$4.000K |
YoY Change | -100.0% | -100.0% | -90.48% |
Gross Profit Margin | -0.5% | ||
Selling, General & Admin | $3.970M | $4.165M | $16.97M |
YoY Change | -13.58% | 0.02% | -10.53% |
% of Gross Profit | |||
Research & Development | $588.0K | $660.0K | $13.04M |
YoY Change | -93.94% | -95.91% | -81.08% |
% of Gross Profit | |||
Depreciation & Amortization | $3.000K | $10.00K | $230.0K |
YoY Change | -97.35% | -91.3% | -20.69% |
% of Gross Profit | |||
Operating Expenses | -$178.0K | $4.825M | $9.405M |
YoY Change | -101.25% | -76.23% | -86.35% |
Operating Profit | $178.0K | -$4.825M | -$8.611M |
YoY Change | -101.24% | -76.25% | -87.51% |
Interest Expense | $96.00K | $167.0K | $537.0K |
YoY Change | 4700.0% | -283.52% | 1276.92% |
% of Operating Profit | 53.93% | ||
Other Income/Expense, Net | $1.000K | $0.00 | |
YoY Change | -98.67% | -100.0% | |
Pretax Income | $274.0K | -$40.11M | -$7.894M |
YoY Change | -101.88% | 97.28% | -91.02% |
Income Tax | $14.00K | $348.0K | $348.0K |
% Of Pretax Income | 5.11% | ||
Net Earnings | $260.0K | -$40.45M | -$8.200M |
YoY Change | -101.79% | 99.0% | -90.67% |
Net Earnings / Revenue | -1032.75% | ||
Basic Earnings Per Share | $0.01 | -$0.26 | |
Diluted Earnings Per Share | $0.01 | -$1.27 | -$0.26 |
COMMON SHARES | |||
Basic Shares Outstanding | 37.76M | 31.49M | 31.55M |
Diluted Shares Outstanding | 37.98M | 31.55M |
Balance Sheet
Concept | 2023 Q1 | 2022 Q4 | 2022 |
---|---|---|---|
SHORT-TERM ASSETS | |||
Cash & Short-Term Investments | $8.099M | $21.67M | $21.67M |
YoY Change | -76.73% | -53.75% | -53.76% |
Cash & Equivalents | $8.100M | $21.67M | $21.67M |
Short-Term Investments | $0.00 | $0.00 | |
Other Short-Term Assets | $915.0K | $1.540M | $1.540M |
YoY Change | -30.79% | -45.14% | -45.14% |
Inventory | $6.122M | ||
Prepaid Expenses | |||
Receivables | $5.000M | $5.000M | $5.000M |
Other Receivables | $0.00 | $0.00 | $0.00 |
Total Short-Term Assets | $14.01M | $28.21M | $28.21M |
YoY Change | -61.82% | -45.21% | -45.21% |
LONG-TERM ASSETS | |||
Property, Plant & Equipment | $1.000K | $4.000K | $70.00K |
YoY Change | -99.97% | -99.59% | -98.12% |
Goodwill | |||
YoY Change | |||
Intangibles | |||
YoY Change | |||
Long-Term Investments | |||
YoY Change | |||
Other Assets | $168.0K | $168.0K | $168.0K |
YoY Change | -64.41% | -64.41% | -64.41% |
Total Long-Term Assets | $4.736M | $238.0K | $238.0K |
YoY Change | 32.62% | -94.31% | -94.31% |
TOTAL ASSETS | |||
Total Short-Term Assets | $14.01M | $28.21M | $28.21M |
Total Long-Term Assets | $4.736M | $238.0K | $238.0K |
Total Assets | $18.75M | $28.44M | $28.44M |
YoY Change | -53.44% | -48.9% | -48.9% |
SHORT-TERM LIABILITIES | |||
YoY Change | |||
Accounts Payable | $16.00K | $194.0K | $194.0K |
YoY Change | -99.66% | -96.98% | -96.98% |
Accrued Expenses | $1.828M | $4.072M | $4.072M |
YoY Change | -78.45% | -45.82% | -45.82% |
Deferred Revenue | |||
YoY Change | |||
Short-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Long-Term Debt Due | |||
YoY Change | |||
Total Short-Term Liabilities | $6.844M | $16.82M | $16.82M |
YoY Change | -48.11% | 18.77% | 18.77% |
LONG-TERM LIABILITIES | |||
Long-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Other Long-Term Liabilities | $4.550M | $0.00 | $0.00 |
YoY Change | -100.0% | -100.0% | |
Total Long-Term Liabilities | $4.550M | $0.00 | $0.00 |
YoY Change | -100.0% | -100.0% | |
TOTAL LIABILITIES | |||
Total Short-Term Liabilities | $6.844M | $16.82M | $16.82M |
Total Long-Term Liabilities | $4.550M | $0.00 | $0.00 |
Total Liabilities | $11.39M | $16.82M | $16.82M |
YoY Change | -13.62% | 15.45% | 15.45% |
SHAREHOLDERS EQUITY | |||
Retained Earnings | -$410.7M | -$410.9M | |
YoY Change | -1.56% | 2.04% | |
Common Stock | $37.00K | $37.00K | |
YoY Change | 19.35% | ||
Preferred Stock | |||
YoY Change | |||
Treasury Stock (at cost) | |||
YoY Change | |||
Treasury Stock Shares | |||
Shareholders Equity | -$25.95M | -$21.69M | $11.62M |
YoY Change | |||
Total Liabilities & Shareholders Equity | $18.75M | $28.44M | $28.44M |
YoY Change | -53.44% | -48.9% | -48.9% |
Cashflow Statement
Concept | 2023 Q1 | 2022 Q4 | 2022 |
---|---|---|---|
OPERATING ACTIVITIES | |||
Net Income | $260.0K | -$40.45M | -$8.200M |
YoY Change | -101.79% | 99.0% | -90.67% |
Depreciation, Depletion And Amortization | $3.000K | $10.00K | $230.0K |
YoY Change | -97.35% | -91.3% | -20.69% |
Cash From Operating Activities | -$6.216M | -$1.475M | -$33.10M |
YoY Change | -48.41% | -91.66% | -60.48% |
INVESTING ACTIVITIES | |||
Capital Expenditures | $1.742M | $0.00 | $0.00 |
YoY Change | -100.0% | ||
Acquisitions | |||
YoY Change | |||
Other Investing Activities | $411.0K | $51.00K | $55.43M |
YoY Change | -83.59% | -98.22% | 13.05% |
Cash From Investing Activities | $411.0K | $51.00K | $55.43M |
YoY Change | -83.59% | -98.22% | 15.02% |
FINANCING ACTIVITIES | |||
Cash Dividend Paid | $7.764M | $45.03M | |
YoY Change | |||
Common Stock Issuance & Retirement, Net | |||
YoY Change | |||
Debt Paid & Issued, Net | |||
YoY Change | |||
Cash From Financing Activities | -7.762M | 0.000 | -45.01M |
YoY Change | -48612.5% | -190.83% | |
NET CHANGE | |||
Cash From Operating Activities | -6.216M | -1.475M | -33.10M |
Cash From Investing Activities | 411.0K | 51.00K | 55.43M |
Cash From Financing Activities | -7.762M | 0.000 | -45.01M |
Net Change In Cash | -13.57M | -1.424M | -22.68M |
YoY Change | 42.36% | -90.38% | -262.16% |
FREE CASH FLOW | |||
Cash From Operating Activities | -$6.216M | -$1.475M | -$33.10M |
Capital Expenditures | $1.742M | $0.00 | $0.00 |
Free Cash Flow | -$7.958M | -$1.475M | -$33.10M |
YoY Change | -91.66% | -60.08% |
Facts In Submission
Frame | Concept Type | Concept / XBRL Key | Value | Unit |
---|---|---|---|---|
CY2021 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-87933000 | |
CY2021 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-2.87 | |
CY2022Q4 | us-gaap |
Commitments And Contingencies
CommitmentsAndContingencies
|
||
CY2022 | dei |
Entity Interactive Data Current
EntityInteractiveDataCurrent
|
Yes | |
CY2022 | dei |
Document Transition Report
DocumentTransitionReport
|
false | |
CY2022 | dei |
Entity File Number
EntityFileNumber
|
000-51173 | |
CY2022 | dei |
Entity Incorporation State Country Code
EntityIncorporationStateCountryCode
|
DE | |
CY2022 | dei |
Entity Tax Identification Number
EntityTaxIdentificationNumber
|
56-2020050 | |
CY2022 | dei |
Entity Address Address Line1
EntityAddressAddressLine1
|
611 Gateway Blvd | |
CY2022 | dei |
Entity Address Address Line2
EntityAddressAddressLine2
|
Suite 710 | |
CY2022 | dei |
Entity Address City Or Town
EntityAddressCityOrTown
|
South San Francisco | |
CY2022 | dei |
Entity Address State Or Province
EntityAddressStateOrProvince
|
CA | |
CY2022 | dei |
Entity Address Postal Zip Code
EntityAddressPostalZipCode
|
94080 | |
CY2022 | dei |
City Area Code
CityAreaCode
|
650 | |
CY2022 | dei |
Local Phone Number
LocalPhoneNumber
|
871-0761 | |
CY2021 | us-gaap |
Operating Expenses
OperatingExpenses
|
95232000 | |
CY2021 | us-gaap |
Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
|
-5000 | |
CY2022 | dei |
Auditor Name
AuditorName
|
EISNERAMPER LLP | |
CY2022 | dei |
Auditor Location
AuditorLocation
|
Philadelphia, Pennsylvania | |
CY2022Q4 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
21666000 | |
CY2021Q4 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
44347000 | |
CY2021Q4 | us-gaap |
Short Term Investments
ShortTermInvestments
|
2504000 | |
CY2021Q4 | us-gaap |
Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
|
2807000 | |
CY2021Q4 | us-gaap |
Assets Current
AssetsCurrent
|
51476000 | |
CY2021Q4 | us-gaap |
Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
|
1977000 | |
CY2021Q4 | us-gaap |
Liabilities Current
LiabilitiesCurrent
|
14165000 | |
CY2022Q4 | us-gaap |
Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
|
66000 | |
CY2022Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
4000 | |
CY2022Q4 | us-gaap |
Assets
Assets
|
28444000 | |
CY2022Q4 | us-gaap |
Accounts Payable Current
AccountsPayableCurrent
|
194000 | |
CY2022Q4 | us-gaap |
Accrued Employee Benefits Current
AccruedEmployeeBenefitsCurrent
|
2582000 | |
CY2021Q4 | us-gaap |
Deferred Revenue Current
DeferredRevenueCurrent
|
230000 | |
CY2022Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
1452000 | |
CY2021Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
4072000 | |
CY2022Q4 | us-gaap |
Common Stock Value
CommonStockValue
|
37000 | |
CY2021Q4 | us-gaap |
Common Stock Value
CommonStockValue
|
31000 | |
CY2021Q4 | us-gaap |
Additional Paid In Capital
AdditionalPaidInCapital
|
443752000 | |
CY2022 | dei |
Entity Filer Category
EntityFilerCategory
|
Non-accelerated Filer | |
CY2022 | dei |
Entity Shell Company
EntityShellCompany
|
false | |
CY2023Q1 | dei |
Entity Common Stock Shares Outstanding
EntityCommonStockSharesOutstanding
|
37759825 | |
CY2022 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-8242000 | |
CY2021 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-87938000 | |
CY2022 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Other
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOther
|
0.0207 | |
CY2021 | cbio |
Effective Income Tax Rate Reconciliation Derecognition
EffectiveIncomeTaxRateReconciliationDerecognition
|
0.0000 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
|
-0.2626 | |
CY2021Q4 | us-gaap |
Commitments And Contingencies
CommitmentsAndContingencies
|
||
CY2021 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
|
P7Y5M15D | |
CY2022 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
|
P7Y5M19D | |
CY2022 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1
|
P5Y11M8D | |
CY2022 | dei |
Document Annual Report
DocumentAnnualReport
|
true | |
CY2022 | dei |
Security12b Title
Security12bTitle
|
Common stock | |
CY2022 | dei |
Security Exchange Name
SecurityExchangeName
|
NASDAQ | |
CY2022 | dei |
Entity Well Known Seasoned Issuer
EntityWellKnownSeasonedIssuer
|
No | |
CY2022 | dei |
Entity Voluntary Filers
EntityVoluntaryFilers
|
No | |
CY2022 | dei |
Entity Current Reporting Status
EntityCurrentReportingStatus
|
Yes | |
CY2022 | dei |
Entity Small Business
EntitySmallBusiness
|
true | |
CY2022 | dei |
Entity Emerging Growth Company
EntityEmergingGrowthCompany
|
false | |
CY2022 | dei |
Icfr Auditor Attestation Flag
IcfrAuditorAttestationFlag
|
false | |
CY2022Q2 | dei |
Entity Public Float
EntityPublicFloat
|
55642222 | |
CY2022 | dei |
Auditor Firm
AuditorFirmId
|
274 | |
CY2022Q4 | us-gaap |
Accounts And Other Receivables Net Current
AccountsAndOtherReceivablesNetCurrent
|
5000000 | |
CY2021Q4 | us-gaap |
Accounts And Other Receivables Net Current
AccountsAndOtherReceivablesNetCurrent
|
1818000 | |
CY2022Q4 | us-gaap |
Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
|
1540000 | |
CY2022Q4 | us-gaap |
Assets Current
AssetsCurrent
|
28206000 | |
CY2022Q4 | us-gaap |
Other Assets Noncurrent
OtherAssetsNoncurrent
|
168000 | |
CY2021Q4 | us-gaap |
Other Assets Noncurrent
OtherAssetsNoncurrent
|
472000 | |
CY2021Q4 | us-gaap |
Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
|
2744000 | |
CY2021Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
970000 | |
CY2021Q4 | us-gaap |
Assets
Assets
|
55662000 | |
CY2021Q4 | us-gaap |
Accounts Payable Current
AccountsPayableCurrent
|
6419000 | |
CY2021Q4 | us-gaap |
Accrued Employee Benefits Current
AccruedEmployeeBenefitsCurrent
|
1467000 | |
CY2022Q4 | us-gaap |
Dividends Payable Current
DividendsPayableCurrent
|
7558000 | |
CY2022Q4 | cbio |
Contingent Value Rights Derivative Liability
ContingentValueRightsDerivativeLiability
|
5000000 | |
CY2022Q4 | us-gaap |
Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
|
38000 | |
CY2022Q4 | us-gaap |
Liabilities Current
LiabilitiesCurrent
|
16824000 | |
CY2021Q4 | us-gaap |
Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
|
408000 | |
CY2022Q4 | us-gaap |
Liabilities
Liabilities
|
16824000 | |
CY2021Q4 | us-gaap |
Liabilities
Liabilities
|
14573000 | |
CY2022Q4 | us-gaap |
Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
|
0.001 | |
CY2021Q4 | us-gaap |
Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
|
0.001 | |
CY2022Q4 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
100000000 | |
CY2021Q4 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
100000000 | |
CY2022Q4 | us-gaap |
Common Stock Shares Issued
CommonStockSharesIssued
|
37756574 | |
CY2022Q4 | us-gaap |
Common Stock Shares Outstanding
CommonStockSharesOutstanding
|
37756574 | |
CY2021Q4 | us-gaap |
Common Stock Shares Issued
CommonStockSharesIssued
|
31409707 | |
CY2021Q4 | us-gaap |
Common Stock Shares Outstanding
CommonStockSharesOutstanding
|
31409707 | |
CY2022Q4 | us-gaap |
Additional Paid In Capital
AdditionalPaidInCapital
|
389210000 | |
CY2022Q4 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-410936000 | |
CY2021Q4 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-402694000 | |
CY2022Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
-21689000 | |
CY2021Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
41089000 | |
CY2022Q4 | us-gaap |
Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
|
28444000 | |
CY2021Q4 | us-gaap |
Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
|
55662000 | |
CY2022 | us-gaap |
Research And Development Expense Excluding Acquired In Process Cost
ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost
|
13037000 | |
CY2021 | us-gaap |
Research And Development Expense Excluding Acquired In Process Cost
ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost
|
68889000 | |
CY2022 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
17366000 | |
CY2021 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
18963000 | |
CY2022 | us-gaap |
Research And Development In Process
ResearchAndDevelopmentInProcess
|
35390000 | |
CY2022 | us-gaap |
Gain Loss On Disposition Of Assets1
GainLossOnDispositionOfAssets1
|
57186000 | |
CY2022 | us-gaap |
Operating Expenses
OperatingExpenses
|
9405000 | |
CY2022 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-8611000 | |
CY2021 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-87894000 | |
CY2022 | cbio |
Interest And Other Income Expense Net
InterestAndOtherIncomeExpenseNet
|
717000 | |
CY2021 | cbio |
Interest And Other Income Expense Net
InterestAndOtherIncomeExpenseNet
|
-39000 | |
CY2022 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-7894000 | |
CY2021 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-87933000 | |
CY2022 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
348000 | |
CY2022 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-8242000 | |
CY2022 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-0.26 | |
CY2022 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-0.26 | |
CY2021 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-2.87 | |
CY2022 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
31545723 | |
CY2022 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
31545723 | |
CY2021 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
30640977 | |
CY2021 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
30640977 | |
CY2022 | us-gaap |
Common Stock Dividends Per Share Cash Paid
CommonStockDividendsPerShareCashPaid
|
1.43 | |
CY2022 | us-gaap |
Common Stock Dividends Per Share Declared
CommonStockDividendsPerShareDeclared
|
0.24 | |
CY2022 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-8242000 | |
CY2021 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-87933000 | |
CY2021 | us-gaap |
Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
|
-5000 | |
CY2020Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
76069000 | |
CY2021 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
3405000 | |
CY2021 | cbio |
Stock Issued During Period From Stock Grants And Stock Options Exercised Value
StockIssuedDuringPeriodFromStockGrantsAndStockOptionsExercisedValue
|
303000 | |
CY2021 | us-gaap |
Adjustments To Additional Paid In Capital Stock Issued Issuance Costs
AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts
|
3563000 | |
CY2021 | us-gaap |
Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
|
49250000 | |
CY2021 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-87933000 | |
CY2021Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
41089000 | |
CY2022 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
1342000 | |
CY2022 | cbio |
Stock Issued During Period From Stock Grants And Stock Options Exercised Value
StockIssuedDuringPeriodFromStockGrantsAndStockOptionsExercisedValue
|
20000 | |
CY2022 | us-gaap |
Stock Issued During Period Value Acquisitions
StockIssuedDuringPeriodValueAcquisitions
|
1691000 | |
CY2022 | us-gaap |
Common Stock Dividends Per Share Cash Paid
CommonStockDividendsPerShareCashPaid
|
1.43 | |
CY2022 | us-gaap |
Dividends Common Stock Cash
DividendsCommonStockCash
|
45031000 | |
CY2022 | us-gaap |
Common Stock Dividends Per Share Declared
CommonStockDividendsPerShareDeclared
|
0.24 | |
CY2022 | us-gaap |
Dividends Common Stock Stock
DividendsCommonStockStock
|
7558000 | |
CY2022 | cbio |
Cvr Derivative Liability
CVRDerivativeLiability
|
5000000 | |
CY2022 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-8242000 | |
CY2022Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
-21689000 | |
CY2022 | us-gaap |
Profit Loss
ProfitLoss
|
-8242000 | |
CY2021 | us-gaap |
Profit Loss
ProfitLoss
|
-87933000 | |
CY2022 | us-gaap |
Research And Development In Process
ResearchAndDevelopmentInProcess
|
35390000 | |
CY2022 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
1342000 | |
CY2021 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
3405000 | |
CY2022 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
230000 | |
CY2021 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
290000 | |
CY2022 | us-gaap |
Provision For Doubtful Accounts
ProvisionForDoubtfulAccounts
|
200000 | |
CY2022 | cbio |
Loss On Lease Termination
LossOnLeaseTermination
|
115000 | |
CY2022 | us-gaap |
Gain Loss On Disposition Of Assets1
GainLossOnDispositionOfAssets1
|
57186000 | |
CY2022 | us-gaap |
Increase Decrease In Accounts And Other Receivables
IncreaseDecreaseInAccountsAndOtherReceivables
|
-1618000 | |
CY2021 | us-gaap |
Increase Decrease In Accounts And Other Receivables
IncreaseDecreaseInAccountsAndOtherReceivables
|
-1495000 | |
CY2022 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
-1609000 | |
CY2021 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
-3880000 | |
CY2022 | us-gaap |
Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
|
-6225000 | |
CY2021 | us-gaap |
Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
|
500000 | |
CY2022 | us-gaap |
Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
|
-1895000 | |
CY2021 | us-gaap |
Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
|
-3680000 | |
CY2022 | cbio |
Increase Decrease In Operating Lease Liability And Right Of Use Asset
IncreaseDecreaseInOperatingLeaseLiabilityAndRightOfUseAsset
|
178000 | |
CY2021 | cbio |
Increase Decrease In Operating Lease Liability And Right Of Use Asset
IncreaseDecreaseInOperatingLeaseLiabilityAndRightOfUseAsset
|
41000 | |
CY2022 | us-gaap |
Increase Decrease In Contract With Customer Liability
IncreaseDecreaseInContractWithCustomerLiability
|
-230000 | |
CY2021 | us-gaap |
Increase Decrease In Contract With Customer Liability
IncreaseDecreaseInContractWithCustomerLiability
|
-1753000 | |
CY2022 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-33096000 | |
CY2021 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-83755000 | |
CY2022 | us-gaap |
Proceeds From Sale Maturity And Collection Of Shortterm Investments
ProceedsFromSaleMaturityAndCollectionOfShorttermInvestments
|
2504000 | |
CY2021 | us-gaap |
Proceeds From Sale Maturity And Collection Of Shortterm Investments
ProceedsFromSaleMaturityAndCollectionOfShorttermInvestments
|
49028000 | |
CY2021 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
839000 | |
CY2022 | us-gaap |
Proceeds From Sale Of Property Plant And Equipment
ProceedsFromSaleOfPropertyPlantAndEquipment
|
498000 | |
CY2022 | us-gaap |
Proceeds From Sale Of Intangible Assets
ProceedsFromSaleOfIntangibleAssets
|
55000000 | |
CY2022 | cbio |
Payment Of Transaction Costs In Connection With Sale Of Complement Portfolio
PaymentOfTransactionCostsInConnectionWithSaleOfComplementPortfolio
|
2576000 | |
CY2022 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
55426000 | |
CY2021 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
48189000 | |
CY2021 | cbio |
Proceeds From Issuance Of Common Stock For Public Offering Net Of Issuance Costs
ProceedsFromIssuanceOfCommonStockForPublicOfferingNetOfIssuanceCosts
|
49250000 | |
CY2022 | us-gaap |
Payments Of Dividends
PaymentsOfDividends
|
45031000 | |
CY2022 | cbio |
Proceeds From Issuance Of Common Stock From Stock Grants And Option Exercises
ProceedsFromIssuanceOfCommonStockFromStockGrantsAndOptionExercises
|
20000 | |
CY2021 | cbio |
Proceeds From Issuance Of Common Stock From Stock Grants And Option Exercises
ProceedsFromIssuanceOfCommonStockFromStockGrantsAndOptionExercises
|
303000 | |
CY2022 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
-45011000 | |
CY2021 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
49553000 | |
CY2022 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
-22681000 | |
CY2021 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
13987000 | |
CY2021Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
|
44347000 | |
CY2020Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
|
30360000 | |
CY2022Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
|
21666000 | |
CY2021Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
|
44347000 | |
CY2022 | cbio |
Non Cash Or Part Non Cash Dividend Declared Unpaid
NonCashOrPartNonCashDividendDeclaredUnpaid
|
7558000 | |
CY2022 | cbio |
Cvr Derivative Liability
CVRDerivativeLiability
|
5000000 | |
CY2021 | cbio |
Non Cash Or Part Non Cash Right Of Use Assets Obtained In Exchange For Operating Lease Liabilities
NonCashOrPartNonCashRightOfUseAssetsObtainedInExchangeForOperatingLeaseLiabilities
|
1850000 | |
CY2021 | cbio |
Non Cash Or Part Non Cash Remeasurement Of Right Of Use Asset Due To Operating Lease Modification
NonCashOrPartNonCashRemeasurementOfRightOfUseAssetDueToOperatingLeaseModification
|
624000 | |
CY2022 | us-gaap |
Nature Of Operations
NatureOfOperations
|
<div style="align:left;"> <table border="0" cellpadding="0" cellspacing="0" style="border-collapse:collapse; width:100%;"> <tr> <td style="width:5.24%;white-space:nowrap" valign="top"> <p style="margin-top:12pt;margin-bottom:0pt;font-weight:bold;font-family:Times New Roman;font-size:10pt;font-style:normal;text-transform:none;font-variant: normal;"><span style="font-weight:bold;font-family:Times New Roman;font-size:10pt;font-style:normal;text-transform:none;font-variant: normal;">1.</span></p></td> <td valign="top"> <p id="NOTES_TO_CONSOLIDATED" style="margin-top:12pt;margin-bottom:0pt;font-weight:bold;font-style:normal;text-transform:none;font-variant: normal;font-family:Times New Roman;font-size:10pt;">Nature of Operations</p></td></tr></table></div> <p style="text-align:justify;margin-top:6pt;margin-bottom:0pt;margin-left:5.24%;text-indent:0%;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">Catalyst Biosciences, Inc. and its subsidiary (the “Company” or “Catalyst”) was a <span style="color:#000000;">biopharmaceutical company with expertise in protease engineering. Prior to ceasing research and development activities in March 2022, the Company had several protease assets that were designed to address unmet medical needs in disorders of the complement or coagulation systems. As discussed further below, the Company recently completed a purchase agreement to acquire a clinical-stage drug candidate for the treatment of NASH (nonalcoholic steatohepatitis, a severe form of nonalcoholic fatty liver disease). Concurrent with this purchase agreement, the Company entered into a separate business combination agreement to acquire an indirect controlling interest in a China-based pharmaceutical company. The Company will continue to evaluate the impact of the novel coronavirus disease (“COVID-19”) pandemic on its business, operations, and cash requirements.</span> <span style="color:#000000;">The Company is located in South San Francisco, California and operates in</span> one segment. </p> <p style="text-align:justify;margin-top:12pt;margin-bottom:0pt;margin-left:5.24%;text-indent:0%;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">On May 19, 2022, Catalyst entered into and closed on an asset purchase agreement with Vertex Pharmaceuticals Inc. (“Vertex”), pursuant to which Vertex acquired Catalyst’s complement portfolio, including CB 2782-PEG and CB 4332, as well as its complement-related intellectual property including the ProTUNE<sup style="font-size:85%;line-height:120%;vertical-align:top">TM</sup> and ImmunoTUNE<sup style="font-size:85%;line-height:120%;vertical-align:top">TM</sup> platforms. See Note 16, <span style="font-style:italic;">Restructuring</span>. After the transaction of its complement portfolio, Catalyst’s product candidates consisted of the coagulation related assets marzeptacog alfa (activated) (“MarzAA”), dalcinonacog alfa (“DalcA”), and CB 2679d-GT. MarzAA is a SQ administered next generation engineered coagulation Factor VIIa (“FVIIa”) for the treatment of episodic bleeding and prophylaxis in subjects with rare bleeding disorders. DalcA is a next-generation SQ administered FIX. CB 2679d-GT is an AAV-based gene therapy construct harboring the DalcA sequence. Both MarzAA and DalcA have shown sustained efficacy and safety in mid-stage clinical trials. CB 2679d-GT has obtained preclinical proof-of-concept. Catalyst sold MarzAA, DalcA and CB-2679d-GT in February 2023 to GC Biopharma Corp. (“GCBP”). See Note 17, <span style="font-style:italic;">Subsequent Events.</span></p> <p style="text-align:justify;margin-top:12pt;margin-bottom:0pt;margin-left:5.24%;text-indent:0%;font-weight:bold;font-style:italic;font-family:Times New Roman;font-size:10pt;text-transform:none;font-variant: normal;">F351 Asset Acquisition</p> <p style="text-align:justify;margin-top:6pt;margin-bottom:0pt;margin-left:5.24%;text-indent:0%;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">On December 26, 2022, the Company executed and closed an Asset Purchase Agreement (the “F351 Agreement”), with GNI Group Ltd. and GNI Hong Kong Limited (together “GNI”) to purchase all of the assets and intellectual property rights primarily related to the proprietary Hydronidone compound (collectively, the “F351 Assets”), other than such assets and intellectual property rights located in the People’s Republic of China. At the closing of the agreement on December 26, 2022, the Company paid $35.0 million in the form of 6,266,521 shares of Catalyst common stock and 12,340 shares of newly designated Series X redeemable convertible preferred stock (“Catalyst Convertible Preferred Stock”). Each share of Catalyst Convertible Preferred Stock is convertible into 10,000 shares of common stock, subject to stockholder approval under Nasdaq rules and subject to a beneficial ownership conversion blocker. For additional information, see Note 4, <span style="font-style:italic;">F351 Asset Acquisition </span>and Note<span style="font-style:italic;"> </span>14<span style="font-style:italic;">, Stockholders’ Equity</span>.</p> <p style="text-align:justify;margin-top:12pt;margin-bottom:0pt;margin-left:5.24%;text-indent:0%;font-weight:bold;font-style:italic;font-family:Times New Roman;font-size:10pt;text-transform:none;font-variant: normal;">Business Combination Agreement</p> <p style="text-align:justify;margin-top:6pt;margin-bottom:0pt;margin-left:5.24%;text-indent:0%;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">Concurrent with the F351 Asset acquisition, the Company signed a definitive agreement with GNI Group Ltd., GNI Hong Kong Limited, GNI USA, Inc., Continent Pharmaceuticals Inc. and Shanghai Genomics, Inc. (collectively, “GNI”) and other minority stockholders to acquire an indirect controlling interest in Beijing Continent Pharmaceutical Co Ltd. (“BC”), a commercial-stage pharmaceutical company based in China and majority-owned subsidiary of GNI, in exchange for newly issued shares of common stock (the “Business Combination Agreement”). The closing of the Business Combination Agreement will be subject to stockholder approval at a stockholder meeting expected to be held in the third quarter of 2023 and certain customary closing conditions. For additional information, see Note 8, <span style="font-style:italic;">Commitments and Contingencies</span>.</p> <p style="text-align:justify;margin-top:12pt;margin-bottom:0pt;margin-left:5.24%;text-indent:0%;font-weight:bold;font-style:italic;font-family:Times New Roman;font-size:10pt;text-transform:none;font-variant: normal;">Contingent Value Rights Agreement</p> <p style="text-align:justify;margin-top:6pt;margin-bottom:0pt;margin-left:5.24%;text-indent:0%;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">Pursuant to the Business Combination Agreement, on December 26, 2022, Catalyst and the Rights Agent (as defined therein) executed a contingent value rights agreement (the “CVR Agreement”), pursuant to which each holder of Catalyst common stock as of January 5, 2023 (the “CVR Holders”), excluding GNI, received one </p> <p style="text-align:justify;margin-top:6pt;margin-bottom:0pt;margin-left:5.24%;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;"><span style="font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">contractual contingent value right</span><span style="font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;"> (a “CVR”)</span><span style="font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;"> issued by the Company for each share of Catalyst common stock held by such holder. Each </span><span style="font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">CVR </span><span style="font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">entitles the holder thereof to receive</span><span style="font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;"> certain cash payments in the future. For additional information, see Note 8, </span><span style="font-style:italic;">Commitments and Contingencies</span><span style="font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">. </span></p> | |
CY2022 | us-gaap |
Number Of Operating Segments
NumberOfOperatingSegments
|
1 | |
CY2022Q3 | us-gaap |
Common Stock Dividends Per Share Cash Paid
CommonStockDividendsPerShareCashPaid
|
1.43 | |
CY2022Q3 | us-gaap |
Dividends Payable Date Of Record Day Month And Year
DividendsPayableDateOfRecordDayMonthAndYear
|
2022-09-06 | |
CY2022Q3 | us-gaap |
Payments Of Dividends Common Stock
PaymentsOfDividendsCommonStock
|
45000000.0 | |
CY2022Q4 | us-gaap |
Payments Of Dividends Common Stock
PaymentsOfDividendsCommonStock
|
7600000 | |
CY2022Q4 | us-gaap |
Dividends Payable Date Of Record Day Month And Year
DividendsPayableDateOfRecordDayMonthAndYear
|
2022-01-05 | |
CY2022 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-8200000 | |
CY2022Q4 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-410900000 | |
CY2022Q4 | us-gaap |
Cash Cash Equivalents And Short Term Investments
CashCashEquivalentsAndShortTermInvestments
|
21700000 | |
CY2022 | us-gaap |
Use Of Estimates
UseOfEstimates
|
<p style="text-align:justify;margin-top:12pt;margin-bottom:0pt;margin-left:5.24%;text-indent:0%;font-weight:bold;font-style:italic;font-family:Times New Roman;font-size:10pt;text-transform:none;font-variant: normal;">Use of Estimates</p> <p style="text-align:justify;margin-top:6pt;margin-bottom:0pt;margin-left:5.24%;text-indent:0%;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">The preparation of consolidated financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the amounts reported in the consolidated financial statements and accompanying notes. On an ongoing basis, management evaluates its estimates, including those related to revenue recognition, allowance of doubtful accounts, contingent value rights, operating lease right-of-use assets and liabilities, accrued expenses, income taxes and stock-based compensation. The Company bases its estimates on various assumptions that the Company believes to be reasonable under the circumstances. Actual results could differ from those estimates.</p> | |
CY2022 | us-gaap |
Derivatives Methods Of Accounting Hedging Derivatives
DerivativesMethodsOfAccountingHedgingDerivatives
|
<p style="text-align:justify;margin-top:12pt;margin-bottom:0pt;margin-left:5.48%;text-indent:0%;font-weight:bold;font-style:italic;font-family:Times New Roman;font-size:10pt;text-transform:none;font-variant: normal;">Derivative Financial Instruments</p> <p style="text-align:justify;margin-top:6pt;margin-bottom:0pt;margin-left:5.24%;text-indent:0%;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">The Company evaluates its contracts to determine if those contracts qualify as derivatives under ASC 815, <span style="font-style:italic;">Derivatives and Hedging</span>. For derivative financial instruments that are accounted for as liabilities, the derivative instrument is initially recorded at its fair value and is then re-valued at each reporting date. Any changes in fair value are recorded as non-operating, non-cash other income or expense for each reporting period. Derivative instrument liabilities are classified in the balance sheet as current or non-current based on whether or not net-cash settlement of the derivative instrument is probable within the next 12 months from the balance sheet date.</p> <p style="text-align:justify;margin-top:12pt;margin-bottom:0pt;margin-left:5.24%;text-indent:0%;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">The Company determined that certain contingent payments under the CVR Agreement qualified as derivatives under ASC 815, and as such, were recorded as a liability on the balance sheet as of December 31, 2022. Refer to Note 5, <span style="font-style:italic;">Fair Value Measurement</span> and Note 8, <span style="font-style:italic;">Commitments and Contingencies</span>, for additional information regarding the CVR derivative liability.</p> | |
CY2022 | us-gaap |
Concentration Risk Credit Risk Financial Instrument Maximum Exposure
ConcentrationRiskCreditRiskFinancialInstrumentMaximumExposure
|
21400000 | |
CY2022Q4 | us-gaap |
Allowance For Doubtful Accounts Receivable
AllowanceForDoubtfulAccountsReceivable
|
200000 | |
CY2021Q4 | us-gaap |
Allowance For Doubtful Accounts Receivable
AllowanceForDoubtfulAccountsReceivable
|
0 | |
CY2022Q4 | us-gaap |
Assets Fair Value Disclosure
AssetsFairValueDisclosure
|
21666000 | |
CY2022Q4 | us-gaap |
Liabilities Fair Value Disclosure
LiabilitiesFairValueDisclosure
|
5000000 | |
CY2021Q4 | us-gaap |
Assets Fair Value Disclosure
AssetsFairValueDisclosure
|
46851000 | |
CY2022Q4 | us-gaap |
Available For Sale Debt Securities Amortized Cost Basis
AvailableForSaleDebtSecuritiesAmortizedCostBasis
|
21666000 | |
CY2022Q4 | us-gaap |
Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
|
21666000 | |
CY2022Q4 | us-gaap |
Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
|
21666000 | |
CY2021Q4 | us-gaap |
Available For Sale Debt Securities Amortized Cost Basis
AvailableForSaleDebtSecuritiesAmortizedCostBasis
|
46851000 | |
CY2021Q4 | us-gaap |
Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
|
46851000 | |
CY2021Q4 | us-gaap |
Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
|
46851000 | |
CY2022 | us-gaap |
Debt Securities Available For Sale Realized Gain Loss
DebtSecuritiesAvailableForSaleRealizedGainLoss
|
0 | |
CY2022Q4 | us-gaap |
Available For Sale Securities Debt Securities Current
AvailableForSaleSecuritiesDebtSecuritiesCurrent
|
0 | |
CY2022Q4 | us-gaap |
Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
|
1417000 | |
CY2021Q4 | us-gaap |
Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
|
509000 | |
CY2022Q4 | cbio |
Accrued Manufacturing Expenses Current
AccruedManufacturingExpensesCurrent
|
22000 | |
CY2021Q4 | cbio |
Accrued Manufacturing Expenses Current
AccruedManufacturingExpensesCurrent
|
1381000 | |
CY2021Q4 | cbio |
Accrued Collaboration Expenses Current
AccruedCollaborationExpensesCurrent
|
868000 | |
CY2021Q4 | cbio |
Accrued Pre Clinical Expenses Current
AccruedPreClinicalExpensesCurrent
|
773000 | |
CY2021Q4 | cbio |
Accrued Clinical Expenses Current
AccruedClinicalExpensesCurrent
|
361000 | |
CY2022Q4 | cbio |
Accrued And Other Current Liabilities
AccruedAndOtherCurrentLiabilities
|
13000 | |
CY2021Q4 | cbio |
Accrued And Other Current Liabilities
AccruedAndOtherCurrentLiabilities
|
180000 | |
CY2022Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
1452000 | |
CY2021Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
4072000 | |
CY2022Q2 | cbio |
Percentage Of Common Stock Filed Lawsuit
PercentageOfCommonStockFiledLawsuit
|
0.05 | |
CY2022 | us-gaap |
Lease Expiration Date1
LeaseExpirationDate1
|
2023-04-30 | |
CY2022 | cbio |
Lessee Operating Lease Renewal Term Description
LesseeOperatingLeaseRenewalTermDescription
|
no stated renewal options | |
CY2021Q4 | us-gaap |
Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
|
600000 | |
CY2022 | us-gaap |
Operating Lease Expense
OperatingLeaseExpense
|
1700000 | |
CY2021 | us-gaap |
Operating Lease Expense
OperatingLeaseExpense
|
1700000 | |
CY2022Q4 | us-gaap |
Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
|
P0Y3M18D | |
CY2021Q4 | us-gaap |
Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
|
P1Y3M18D | |
CY2022Q4 | us-gaap |
Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
|
0.043 | |
CY2021Q4 | us-gaap |
Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
|
0.048 | |
CY2022Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Next Twelve Months
LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
|
38000 | |
CY2022Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
|
38000 | |
CY2022Q4 | us-gaap |
Operating Lease Liability
OperatingLeaseLiability
|
38000 | |
CY2022 | cbio |
Cash Paid For Amounts Included In The Measurement Of Lease Liabilities
CashPaidForAmountsIncludedInTheMeasurementOfLeaseLiabilities
|
1512000 | |
CY2021 | cbio |
Cash Paid For Amounts Included In The Measurement Of Lease Liabilities
CashPaidForAmountsIncludedInTheMeasurementOfLeaseLiabilities
|
1641000 | |
CY2021 | cbio |
Prepaid Cash Payment For Lease Liabilities
PrepaidCashPaymentForLeaseLiabilities
|
208000 | |
CY2022 | us-gaap |
Operating Lease Payments
OperatingLeasePayments
|
1512000 | |
CY2021 | us-gaap |
Operating Lease Payments
OperatingLeasePayments
|
1849000 | |
CY2022Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant
ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant
|
12990839 | |
CY2022 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested Number Of Shares
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares
|
0 | |
CY2022Q3 | us-gaap |
Payments Of Dividends Common Stock
PaymentsOfDividendsCommonStock
|
45000000.0 | |
CY2022Q3 | us-gaap |
Common Stock Dividends Per Share Cash Paid
CommonStockDividendsPerShareCashPaid
|
1.43 | |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
|
2603630 | |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
|
7.70 | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
|
10270911 | |
CY2022 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
|
1.34 | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures And Expirations In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod
|
4148455 | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures And Expirations In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice
|
4.96 | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Expirations In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod
|
47319 | |
CY2022 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Expirations In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice
|
13.27 | |
CY2022Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
|
8678767 | |
CY2022Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
|
1.42 | |
CY2022Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
|
1051000 | |
CY2022Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber
|
4317076 | |
CY2022Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice
|
2.38 | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
0.96 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
4.00 | |
CY2022 | us-gaap |
Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
|
0 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
3000 | |
CY2022 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested In Period Fair Value1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1
|
1900000 | |
CY2021 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested In Period Fair Value1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1
|
2600000 | |
CY2022 | us-gaap |
Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
|
1342000 | |
CY2021 | us-gaap |
Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
|
3405000 | |
CY2022 | us-gaap |
Stock Issued During Period Shares Issued For Services
StockIssuedDuringPeriodSharesIssuedForServices
|
32684 | |
CY2021 | us-gaap |
Stock Issued During Period Shares Issued For Services
StockIssuedDuringPeriodSharesIssuedForServices
|
56912 | |
CY2022 | us-gaap |
Current Federal Tax Expense Benefit
CurrentFederalTaxExpenseBenefit
|
341000 | |
CY2022 | us-gaap |
Current State And Local Tax Expense Benefit
CurrentStateAndLocalTaxExpenseBenefit
|
7000 | |
CY2022 | us-gaap |
Current Federal State And Local Tax Expense Benefit
CurrentFederalStateAndLocalTaxExpenseBenefit
|
348000 | |
CY2022 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.2100 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.2100 | |
CY2022 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.0001 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.0000 | |
CY2022 | cbio |
Effective Income Tax Rate Reconciliation Permanent Differences
EffectiveIncomeTaxRateReconciliationPermanentDifferences
|
-0.0100 | |
CY2021 | cbio |
Effective Income Tax Rate Reconciliation Permanent Differences
EffectiveIncomeTaxRateReconciliationPermanentDifferences
|
-0.0035 | |
CY2022 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits
EffectiveIncomeTaxRateReconciliationTaxCredits
|
0.4208 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits
EffectiveIncomeTaxRateReconciliationTaxCredits
|
0.0586 | |
CY2022 | cbio |
Effective Income Tax Rate Reconciliation Derecognition
EffectiveIncomeTaxRateReconciliationDerecognition
|
-1.3900 | |
CY2022 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
|
0.6924 | |
CY2022 | cbio |
Effective Income Tax Rate Reconciliation Fixed Assets Other Adjustment Percent
EffectiveIncomeTaxRateReconciliationFixedAssetsOtherAdjustmentPercent
|
0.0119 | |
CY2021 | cbio |
Effective Income Tax Rate Reconciliation Fixed Assets Other Adjustment Percent
EffectiveIncomeTaxRateReconciliationFixedAssetsOtherAdjustmentPercent
|
0.0000 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Other
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOther
|
-0.0025 | |
CY2022 | us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
0.0441 | |
CY2021 | us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
0.0000 | |
CY2022Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Reserves And Accruals
DeferredTaxAssetsTaxDeferredExpenseReservesAndAccruals
|
1273000 | |
CY2021Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Reserves And Accruals
DeferredTaxAssetsTaxDeferredExpenseReservesAndAccruals
|
1000000 | |
CY2022Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
40770000 | |
CY2021Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
47541000 | |
CY2022Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Research
DeferredTaxAssetsTaxCreditCarryforwardsResearch
|
4463000 | |
CY2021Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Research
DeferredTaxAssetsTaxCreditCarryforwardsResearch
|
12939000 | |
CY2022Q4 | cbio |
Deferred Tax Assets Fixed Assets And Intangibles
DeferredTaxAssetsFixedAssetsAndIntangibles
|
9510000 | |
CY2021Q4 | cbio |
Deferred Tax Assets Fixed Assets And Intangibles
DeferredTaxAssetsFixedAssetsAndIntangibles
|
3000 | |
CY2022Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
56016000 | |
CY2021Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
61483000 | |
CY2022 | us-gaap |
Valuation Allowances And Reserves Period Increase Decrease
ValuationAllowancesAndReservesPeriodIncreaseDecrease
|
-5500000 | |
CY2021 | us-gaap |
Valuation Allowances And Reserves Period Increase Decrease
ValuationAllowancesAndReservesPeriodIncreaseDecrease
|
23100000 | |
CY2022 | cbio |
Research And Development Tax Credit Carry Forwards Derecognized
ResearchAndDevelopmentTaxCreditCarryForwardsDerecognized
|
26100000 | |
CY2022Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
1900000 | |
CY2021Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
4700000 | |
CY2020Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
2955000 | |
CY2021 | us-gaap |
Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions
UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions
|
1749000 | |
CY2021Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
4704000 | |
CY2022 | cbio |
Unrecognized Tax Benefits Increase Decrease Resulting From Prior Period Tax Positions
UnrecognizedTaxBenefitsIncreaseDecreaseResultingFromPriorPeriodTaxPositions
|
-2841000 | |
CY2022 | us-gaap |
Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions
UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions
|
20000 | |
CY2022Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
1883000 | |
CY2022Q4 | us-gaap |
Income Tax Examination Penalties And Interest Accrued
IncomeTaxExaminationPenaltiesAndInterestAccrued
|
0 | |
CY2021Q4 | us-gaap |
Income Tax Examination Penalties And Interest Accrued
IncomeTaxExaminationPenaltiesAndInterestAccrued
|
0 | |
CY2022Q4 | us-gaap |
Liability For Uncertain Tax Positions Current
LiabilityForUncertainTaxPositionsCurrent
|
0 | |
CY2021Q4 | us-gaap |
Liability For Uncertain Tax Positions Current
LiabilityForUncertainTaxPositionsCurrent
|
0 | |
CY2022 | us-gaap |
Deferred Revenue Revenue Recognized1
DeferredRevenueRevenueRecognized1
|
200000 | |
CY2022 | us-gaap |
Interest Income Expense Nonoperating Net
InterestIncomeExpenseNonoperatingNet
|
537000 | |
CY2021 | us-gaap |
Interest Income Expense Nonoperating Net
InterestIncomeExpenseNonoperatingNet
|
39000 | |
CY2022 | cbio |
Gain Loss From Extinguishment Of Liability
GainLossFromExtinguishmentOfLiability
|
180000 | |
CY2021 | us-gaap |
Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
|
-78000 | |
CY2022 | cbio |
Interest And Other Income Expense Net
InterestAndOtherIncomeExpenseNet
|
717000 | |
CY2021 | cbio |
Interest And Other Income Expense Net
InterestAndOtherIncomeExpenseNet
|
-39000 | |
CY2022Q4 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
100000000 | |
CY2022Q4 | us-gaap |
Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
|
0.001 | |
CY2022 | us-gaap |
Common Stock Voting Rights
CommonStockVotingRights
|
one vote | |
CY2022Q4 | us-gaap |
Preferred Stock Shares Authorized
PreferredStockSharesAuthorized
|
5000000 | |
CY2022Q4 | us-gaap |
Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
|
0.001 | |
CY2022 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
132078767 | |
CY2021 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
2603715 | |
CY2021Q4 | us-gaap |
Restructuring And Related Cost Number Of Positions Eliminated Period Percent
RestructuringAndRelatedCostNumberOfPositionsEliminatedPeriodPercent
|
0.35 | |
CY2021 | us-gaap |
Severance Costs1
SeveranceCosts1
|
400000 | |
CY2021 | cbio |
Charges Related To Write Off Of Prepaid Manufacturing Cost
ChargesRelatedToWriteOffOfPrepaidManufacturingCost
|
3800000 | |
CY2021 | cbio |
Restructuring Liability
RestructuringLiability
|
200000 | |
CY2022Q1 | us-gaap |
Restructuring And Related Cost Number Of Positions Eliminated
RestructuringAndRelatedCostNumberOfPositionsEliminated
|
22 | |
CY2022Q1 | cbio |
Remaining Number Of Full Time Employees
RemainingNumberOfFullTimeEmployees
|
5 | |
CY2022 | us-gaap |
Restructuring Charges
RestructuringCharges
|
1011000 | |
CY2021 | us-gaap |
Restructuring Charges
RestructuringCharges
|
4168000 |