2023 Q1 Form 10-K Financial Statement

#000095017023011133 Filed on March 31, 2023

View on sec.gov

Income Statement

Concept 2023 Q1 2022 Q4 2022
Revenue $64.52K $63.57K $123.4K
YoY Change 40.17% 3176.8% -96.02%
Cost Of Revenue
YoY Change
Gross Profit
YoY Change
Gross Profit Margin
Selling, General & Admin $1.925M $1.344M $6.217M
YoY Change 15.32% -18.68% -4.47%
% of Gross Profit
Research & Development $2.854M $3.054M $12.03M
YoY Change -5.4% -9.91% 5.95%
% of Gross Profit
Depreciation & Amortization $5.043K $5.040K $6.723K
YoY Change
% of Gross Profit
Operating Expenses $4.779M $4.399M $18.25M
YoY Change 1.98% -12.79% 2.16%
Operating Profit -$4.715M -$18.13M
YoY Change 1.6% 22.77%
Interest Expense $237.2K $55.92K $74.45K
YoY Change 4743300.0% -35050.0% 273.69%
% of Operating Profit
Other Income/Expense, Net
YoY Change
Pretax Income -$4.478M -$4.279M -$18.05M
YoY Change -3.51% -15.13% 22.1%
Income Tax $0.00
% Of Pretax Income
Net Earnings -$4.478M -$4.279M -$18.05M
YoY Change -3.51% -15.13% 22.1%
Net Earnings / Revenue -6940.03% -6731.24% -14625.85%
Basic Earnings Per Share -$0.16 -$0.72
Diluted Earnings Per Share -$0.16 -$0.17 -$0.72
COMMON SHARES
Basic Shares Outstanding 28.98M 25.23M 25.21M
Diluted Shares Outstanding 27.51M 25.21M

Balance Sheet

Concept 2023 Q1 2022 Q4 2022
SHORT-TERM ASSETS
Cash & Short-Term Investments $25.72M $23.05M $23.05M
YoY Change -29.75% -43.43% -43.44%
Cash & Equivalents $3.957M $7.190M
Short-Term Investments $21.76M $15.86M $15.86M
Other Short-Term Assets $1.846M $1.281M $1.281M
YoY Change 6.68% -20.42% -20.42%
Inventory
Prepaid Expenses $923.1K $1.118M
Receivables $64.52K $39.88K $39.88K
Other Receivables $0.00 $0.00 $0.00
Total Short-Term Assets $27.63M $24.37M $24.37M
YoY Change -28.03% -42.62% -42.62%
LONG-TERM ASSETS
Property, Plant & Equipment $231.5K $236.5K $565.2K
YoY Change
Goodwill
YoY Change
Intangibles
YoY Change
Long-Term Investments
YoY Change
Other Assets
YoY Change
Total Long-Term Assets $534.8K $565.2K $565.2K
YoY Change -13368900.0%
TOTAL ASSETS
Total Short-Term Assets $27.63M $24.37M $24.37M
Total Long-Term Assets $534.8K $565.2K $565.2K
Total Assets $28.16M $24.94M $24.94M
YoY Change -26.64% -41.28% -41.28%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable $959.1K $1.151M $1.151M
YoY Change 18.96% 5.63% 5.63%
Accrued Expenses $1.558M $2.398M $2.544M
YoY Change -56.4% -11.68% -6.31%
Deferred Revenue
YoY Change
Short-Term Debt $0.00 $0.00 $0.00
YoY Change
Long-Term Debt Due
YoY Change
Total Short-Term Liabilities $2.664M $3.695M $3.695M
YoY Change -39.18% -8.85% -8.85%
LONG-TERM LIABILITIES
Long-Term Debt $0.00 $0.00 $0.00
YoY Change
Other Long-Term Liabilities $178.1K $205.5K $205.5K
YoY Change
Total Long-Term Liabilities $178.1K $205.5K $205.5K
YoY Change
TOTAL LIABILITIES
Total Short-Term Liabilities $2.664M $3.695M $3.695M
Total Long-Term Liabilities $178.1K $205.5K $205.5K
Total Liabilities $2.842M $3.901M $3.901M
YoY Change -35.11% -3.79% -3.79%
SHAREHOLDERS EQUITY
Retained Earnings -$52.35M -$47.87M
YoY Change 51.92% 60.55%
Common Stock $77.50M $68.80M
YoY Change 13.2% 0.83%
Preferred Stock
YoY Change
Treasury Stock (at cost) $300.4K
YoY Change -42.21%
Treasury Stock Shares
Shareholders Equity $25.32M $21.04M $21.04M
YoY Change
Total Liabilities & Shareholders Equity $28.16M $24.94M $24.94M
YoY Change -26.64% -41.28% -41.28%

Cashflow Statement

Concept 2023 Q1 2022 Q4 2022
OPERATING ACTIVITIES
Net Income -$4.478M -$4.279M -$18.05M
YoY Change -3.51% -15.13% 22.1%
Depreciation, Depletion And Amortization $5.043K $5.040K $6.723K
YoY Change
Cash From Operating Activities -$5.972M -$3.556M -$17.35M
YoY Change 51.8% -13.17% 21.36%
INVESTING ACTIVITIES
Capital Expenditures $0.00 $243.3K
YoY Change
Acquisitions
YoY Change
Other Investing Activities -$5.839M $4.963M -$15.76M
YoY Change
Cash From Investing Activities -$5.839M $4.963M -$16.01M
YoY Change
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net
YoY Change
Debt Paid & Issued, Net
YoY Change
Cash From Financing Activities 8.579M 0.000 -204.8K
YoY Change -4289.61% -100.5%
NET CHANGE
Cash From Operating Activities -5.972M -3.556M -17.35M
Cash From Investing Activities -5.839M 4.963M -16.01M
Cash From Financing Activities 8.579M 0.000 -204.8K
Net Change In Cash -3.232M 1.407M -33.56M
YoY Change -21.91% -134.34% -225.25%
FREE CASH FLOW
Cash From Operating Activities -$5.972M -$3.556M -$17.35M
Capital Expenditures $0.00 $243.3K
Free Cash Flow -$3.556M -$17.59M
YoY Change 23.06%

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CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
7188553
CY2021Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
40750133
CY2022 us-gaap Interest Paid Net
InterestPaidNet
973
CY2021 us-gaap Interest Paid Net
InterestPaidNet
1148
CY2022 ikt Ppp Loans Forgiveness
PppLoansForgiveness
0
CY2021 ikt Ppp Loans Forgiveness
PppLoansForgiveness
27550
CY2022 ikt Cash Paid For Amounts Included In The Measurement Of Operating Lease Liabilities
CashPaidForAmountsIncludedInTheMeasurementOfOperatingLeaseLiabilities
5553
CY2021 ikt Cash Paid For Amounts Included In The Measurement Of Operating Lease Liabilities
CashPaidForAmountsIncludedInTheMeasurementOfOperatingLeaseLiabilities
0
CY2022 us-gaap Nature Of Operations
NatureOfOperations
<p style="text-indent:0.0%;font-size:10.0pt;margin-top:12.0pt;font-family:Times New Roman;margin-bottom:0.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:bold;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">1. </span><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:bold;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;"> Nature of Business</span><span style="color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:bold;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;"> </span></p><p style="text-indent:4.533%;font-size:10.0pt;margin-top:12.0pt;font-family:Times New Roman;margin-bottom:0.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">We are a clinical-stage pharmaceutical company developing protein kinase inhibitor therapeutics to modify the course of Parkinson’s disease ("PD"), Parkinson’s-related disorders and other diseases of the Abelson Tyrosine Kinases. The Company’s multi-therapeutic pipeline has a primary focus on neurodegeneration and its lead program utilizing IkT-148009, c-Abl inhibitor, targets the treatment of Parkinson’s disease inside and outside the brain as well as other diseases that arise from Abelson Tyrosine Kinases. In 2021, we commenced clinical development of IkT-148009, which we believe can modify the course of Parkinson’s disease including its manifestation in the gastrointestinal tract, or GI. The FDA review of the Phase 1/1b data and the protocol for the Phase 2a three-month dosing study resulted in the FDA agreeing with the Company’s view that it was appropriate for the Phase 2a study to begin, prompting the Company to initiate the Phase 2a study, the 201 trial, at the end of May 2022. In October 2022, an IND to expand use of IkT-148009 into the Parkinson’s-related disease Multiple System Atrophy, or MSA, was filed with the FDA. On November 7, 2022, following review of the IND for IkT-148009 as a treatment for MSA, the FDA notified the Company that it was placing the IkT-148009 programs for Parkinson’s disease and MSA on clinical hold. The FDA lifted the full clinical hold in January 2023 for the Parkinson’s programs and in March 2023 on the MSA program, opening the IND for MSA. Twenty of 35 planned sites will be open as of this filing. The 201 in Parkinson’s trial will start screening patients for enrollment at 50 mg and 100 mg, with the 200 mg dose added back into the trial following submission of the safety and steady-state pharmacokinetic data of the 200 mg dose that was collected in March 2023. Once this data is submitted, the 200 mg dose will be added to the trial after 15 patients have been randomized to 50 mg, 100 mg or placebo groups. The FDA further requested the measurement of visual acuity and examination of the cornea and lens to complement the analysis of retina, macula and fundus that was already part of the ocular monitoring program in the 201 trial.</span></p><p style="text-indent:4.533%;font-size:10.0pt;margin-top:12.0pt;font-family:Times New Roman;margin-bottom:0.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">The Company is also developing platform technologies for alternate ways to deliver protein kinase inhibitors in patients. Our first example of this technology is IkT-001Pro, a prodrug of the anticancer agent imatinib mesylate, to treat Stable Phase Chronic Myelogenous Leukemia (SP-CML). Pursuant to its IND which was cleared by the FDA in August 2022, IkT-001Pro is being evaluated in a two-part dose finding/dose equivalence study in up to 59 healthy volunteers (the 501 trial). The study is designed to evaluate the 96-hour pharmacokinetics of imatinib delivered as IkT-001Pro and determine the dose of IkT-001Pro that can deliver the equivalent 400 mg imatinib, the standard-of-care dose for SP-CML. As of this writing, three of four dose escalation cohorts have completed the trial. Only four mild adverse events have been observed, none of clinical significance for IkT-001Pro. IkT-001Pro has high oral bioavailability and a pharmacokinetic profile of delivered imatinib that closely matches the exposure of imatinib delivered as 400 mg imatinib mesylate. Following the 501 study, Inhibikase will confer with the FDA and seek agreement on the requirements for the NDA process following the proposed approval path for IkT-001Pro under the 505(b)(2) approval pathway. The Company will simultaneously pursue a superiority study comparing the selected doses of IkT-001Pro to standard-of-care 400 mg imatinib in SP-CML patients using a novel, two-period-wait-list- crossover-switching study.</span></p><p style="text-indent:4.533%;font-size:10.0pt;margin-top:12.0pt;font-family:Times New Roman;margin-bottom:0.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;"> For both IkT-148009 and IkT-001Pro, we have completed clinical batch manufacturing of a film-coated tablet formulation. The bioequivalence studies with IkT-001Pro have already implemented these tablets into the study. A pharmacokinetic bridging study with two different tablet formulations of IkT-148009 is planned to be completed in 2023.</span></p><p style="text-indent:0.0%;font-size:10.0pt;margin-top:9.0pt;font-family:Times New Roman;margin-bottom:0.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:bold;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">Liquidity</span></p><p style="text-indent:3.733%;font-size:10.0pt;margin-top:9.0pt;font-family:Times New Roman;margin-bottom:0.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">The Company has recognized recurring losses. At December 31, 2022, the Company had working capital of $</span><span style="font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">20,675,677</span><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">, an accumulated deficit of $</span><span style="font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">47,871,842</span><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">, cash and cash equivalents of $</span><span style="font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">7,188,553</span><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">, marketable securities of $</span><span style="font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">15,861,620</span><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;"> and accounts payable and accrued expenses of $</span><span style="font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">3,549,609</span><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">.</span><span style="color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;"> </span></p><p style="text-indent:3.733%;font-size:10.0pt;margin-top:9.0pt;font-family:Times New Roman;margin-bottom:0.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">The future success of the Company is dependent on its ability to successfully obtain additional working capital, obtain regulatory approval for and successfully launch and commercialize its product candidates and to ultimately attain profitable operations. Historically, the Company has funded its operations primarily through cash received in connection with revenue from its various grant programs. In addition, in December 2020, June 2021 and January 2023 the Company raised approximately $</span><span style="font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">14.6</span><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;"> million, $</span><span style="font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">41.1</span><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;"> million a</span><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">nd $</span><span style="font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">8.7</span><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;"> million in net proceeds for working capital </span><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">from its initial public offering (“IPO”), June 2021 Offering and January 2023 Offering, respectively.</span><span style="color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;"> </span></p><p style="text-indent:3.733%;font-size:10.0pt;margin-top:9.0pt;font-family:Times New Roman;margin-bottom:0.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">The Company is subject to a variety of risks similar to other early-stage life science companies including, but not limited to, the successful development, regulatory approval, and market acceptance of the Company’s product candidates, development by its competitors of new technological innovations, protection of proprietary technology, and raising additional working capital. The Company has incurred significant research and development expenses and general and administrative expenses related to its product candidate programs. The Company anticipates costs and expenses to increase in the future as the Company continues to develop its product candidates.</span><span style="color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;"> </span></p><p style="text-indent:3.733%;font-size:10.0pt;margin-top:9.0pt;font-family:Times New Roman;margin-bottom:0.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">The Company may seek to fund its operations through additional public equity, private equity, or debt financings, as well as other sources. However, the Company may be unable to raise additional working capital, or if it is able to raise additional capital, it may be unable to do so on commercially favorable terms. The Company’s failure to raise capital or enter into such other arrangements if and when needed would have a negative impact on the Company’s business, results of operations and financial condition and the Company’s ability to continue to develop its product candidates.</span></p><p style="text-indent:3.733%;font-size:10.0pt;margin-top:9.0pt;font-family:Times New Roman;margin-bottom:0.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">The Company estimates that its working capital at December 31, 2022 and funds raised from the January 2023 Offering is sufficient to fund its normal operations into the fourth quarter of 2024.</span><span style="color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;"> </span></p><p style="text-indent:3.733%;font-size:10.0pt;margin-top:9.0pt;font-family:Times New Roman;margin-bottom:0.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">The accompanying consolidated financial statements have been prepared on a going concern basis, which contemplates the realization of assets and satisfaction of liabilities in the ordinary course of business. The consolidated financial statements do not include any adjustments relating to the recoverability and classification of recorded asset amounts or the amounts and classification of liabilities that might result from the outcome of the uncertainties described above.</span><span style="color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;"> </span></p>
CY2022Q4 ikt Working Capital
WorkingCapital
20675677
CY2022Q4 us-gaap Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
-47871842
CY2022Q4 us-gaap Cash
Cash
7188553
CY2022Q4 us-gaap Marketable Securities
MarketableSecurities
15861620
CY2022Q4 us-gaap Accounts Payable And Accrued Liabilities Current And Noncurrent
AccountsPayableAndAccruedLiabilitiesCurrentAndNoncurrent
3549609
CY2022 us-gaap Use Of Estimates
UseOfEstimates
<p style="text-indent:0.0%;font-size:10.0pt;margin-top:12.0pt;font-family:Times New Roman;margin-bottom:6.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:bold;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">Use of Estimates</span><span style="color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:bold;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;"> </span></p><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">The preparation of the Company’s financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the amounts reported in the financial statements and accompanying notes. The Company utilizes certain estimates in the determination of our liquidity and working capital adequacy, the fair value of its stock options and warrants, deferred tax valuation allowances and revenue recognition, to record expenses relating to research and development contracts and accrued expenses. The Company bases its estimates on historical experience and other market-specific or other relevant assumptions that it believes to be reasonable under the circumstances. Actual results could differ from such estimates.</span>
CY2022Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
7190000
CY2021Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
40750000
CY2022Q4 us-gaap Allowance For Doubtful Accounts Premiums And Other Receivables
AllowanceForDoubtfulAccountsPremiumsAndOtherReceivables
0
CY2021Q4 us-gaap Allowance For Doubtful Accounts Premiums And Other Receivables
AllowanceForDoubtfulAccountsPremiumsAndOtherReceivables
0
CY2022Q4 ikt Accrued Consulting Current
AccruedConsultingCurrent
232390
CY2021Q4 ikt Accrued Consulting Current
AccruedConsultingCurrent
210000
CY2022Q4 us-gaap Other Accrued Liabilities Current And Noncurrent
OtherAccruedLiabilitiesCurrentAndNoncurrent
459997
CY2021Q4 us-gaap Other Accrued Liabilities Current And Noncurrent
OtherAccruedLiabilitiesCurrentAndNoncurrent
421734
CY2022Q4 ikt Accrued Research And Development Current
AccruedResearchAndDevelopmentCurrent
1696129
CY2021Q4 ikt Accrued Research And Development Current
AccruedResearchAndDevelopmentCurrent
2077932
CY2022Q4 ikt Accrued Interest Current
AccruedInterestCurrent
0
CY2021Q4 ikt Accrued Interest Current
AccruedInterestCurrent
968
CY2022Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
9920
CY2021Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
5127
CY2022Q4 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
2398436
CY2021Q4 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
2715761
CY2021Q4 us-gaap Marketable Securities
MarketableSecurities
0
CY2022Q4 us-gaap Available For Sale Debt Securities Amortized Cost Basis
AvailableForSaleDebtSecuritiesAmortizedCostBasis
15756902
CY2022 us-gaap Debt Securities Available For Sale Unrealized Gain Loss
DebtSecuritiesAvailableForSaleUnrealizedGainLoss
104718
CY2022 us-gaap Debt Securities Realized Gain Loss
DebtSecuritiesRealizedGainLoss
0
CY2022Q4 us-gaap Marketable Securities
MarketableSecurities
15861620
CY2022 us-gaap Proceeds From Sale And Maturity Of Marketable Securities
ProceedsFromSaleAndMaturityOfMarketableSecurities
4960000
CY2022 us-gaap Marketable Securities Realized Gain Loss
MarketableSecuritiesRealizedGainLoss
0
CY2022Q1 us-gaap Stock Option Exercise Price Increase
StockOptionExercisePriceIncrease
2.02
CY2022Q1 ikt Additional Rights Or Options Granted
AdditionalRightsOrOptionsGranted
0
CY2022Q4 us-gaap Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
243255
CY2022Q4 us-gaap Property Plant And Equipment And Finance Lease Right Of Use Asset Accumulated Depreciation And Amortization
PropertyPlantAndEquipmentAndFinanceLeaseRightOfUseAssetAccumulatedDepreciationAndAmortization
6723
CY2022Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
236532
CY2022 us-gaap Depreciation
Depreciation
6723
CY2021Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
0
CY2020Q1 us-gaap Debt Instrument Issuance Date1
DebtInstrumentIssuanceDate1
2020-02-05
CY2020Q1 us-gaap Debt Instrument Interest Rate Stated Percentage
DebtInstrumentInterestRateStatedPercentage
0.0159
CY2020Q1 us-gaap Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1
ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
4.87
CY2022 ikt Common Stock Per Share Entitled To Vote
CommonStockPerShareEntitledToVote
1
CY2022Q4 us-gaap Common Stock Capital Shares Reserved For Future Issuance
CommonStockCapitalSharesReservedForFutureIssuance
5956282
CY2021Q2 ikt Common Stock In Connection With Exercise Of Non Qualified Stock Options Shares
CommonStockInConnectionWithExerciseOfNonQualifiedStockOptionsShares
73496
CY2021Q2 us-gaap Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
90415
CY2021Q2 us-gaap Stock Option Exercise Price Increase
StockOptionExercisePriceIncrease
0.38
CY2021Q2 ikt Common Stock In Connection With Exercise Of Non Qualified Stock Options Shares Withheld For Taxes
CommonStockInConnectionWithExerciseOfNonQualifiedStockOptionsSharesWithheldForTaxes
16919
CY2021Q3 ikt Common Stock In Connection With Exercise Of Non Qualified Stock Options Shares
CommonStockInConnectionWithExerciseOfNonQualifiedStockOptionsShares
21853
CY2021Q3 us-gaap Stock Option Exercise Price Increase
StockOptionExercisePriceIncrease
2.02
CY2022Q1 ikt Common Stock In Connection With Exercise Of Non Qualified Stock Options Shares
CommonStockInConnectionWithExerciseOfNonQualifiedStockOptionsShares
21853
CY2022Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
300000
CY2022 ikt Percentage Of Stock Option Exercised
PercentageOfStockOptionExercised
100
CY2022 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
0
CY2022 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
0.64
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
2.24
CY2022 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
0.0217
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
0.0059
CY2022 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
0.0000
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
0.0000
CY2022 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
0.8488
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
0.8222
CY2022 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1
P4Y4M20D
CY2021 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1
P3Y11M19D
CY2022 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested In Period Fair Value1
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618157
CY2021 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested In Period Fair Value1
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CY2022 us-gaap Allocated Share Based Compensation Expense
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CY2021 us-gaap Allocated Share Based Compensation Expense
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0.049
CY2018Q4 ikt Class Of Warrant Or Right Issued
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CY2021Q4 us-gaap Warrants And Rights Outstanding Term
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P7Y
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4.79
CY2019Q1 us-gaap Warrants And Rights Outstanding Term
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P7Y
CY2019Q1 ikt Class Of Warrant Or Right Issued
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20533
CY2019Q1 us-gaap Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1
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4.79
CY2019Q1 us-gaap Warrants And Rights Outstanding
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CY2020Q1 ikt Class Of Warrant Or Right Issued
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5.67
CY2020Q1 us-gaap Warrants And Rights Outstanding Term
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P7Y
CY2020Q1 us-gaap Warrants And Rights Outstanding
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CY2020Q3 ikt Class Of Warrant Or Right Outstanding Vested
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21854
CY2020Q3 us-gaap Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1
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5.90
CY2020Q3 us-gaap Warrants And Rights Outstanding Term
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P7Y
CY2020Q3 ikt Class Of Warrant Or Right Issued
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5.90
CY2020Q3 us-gaap Warrants And Rights Outstanding Term
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P7Y
CY2020Q4 us-gaap Warrants And Rights Outstanding Term
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CY2020Q4 ikt Class Of Warrant Or Right Issued
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102435
CY2020Q4 us-gaap Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1
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10.00
CY2020Q4 us-gaap Warrants And Rights Outstanding
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685441
CY2021Q4 us-gaap Warrants And Rights Outstanding
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100
CY2022Q4 us-gaap Warrants And Rights Outstanding Term
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P5Y
CY2021 ikt Class Of Warrant Or Right Exercised In Period
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0
CY2022 ikt Class Of Warrant Or Right Exercised In Period
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CY2022 us-gaap Net Income Loss
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-18054155
CY2021 us-gaap Net Income Loss
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-14786063
CY2022 us-gaap Weighted Average Number Of Shares Outstanding Basic
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25211726
CY2022 us-gaap Weighted Average Number Of Diluted Shares Outstanding
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25211726
CY2021 us-gaap Weighted Average Number Of Shares Outstanding Basic
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18209198
CY2021 us-gaap Weighted Average Number Of Diluted Shares Outstanding
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18209198
CY2022 us-gaap Earnings Per Share Basic
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-0.72
CY2022 us-gaap Earnings Per Share Diluted
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-0.72
CY2021 us-gaap Earnings Per Share Basic
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-0.81
CY2021 us-gaap Earnings Per Share Diluted
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-0.81
CY2022 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
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5956282
CY2021 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
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5158357
CY2022 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
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0.2100
CY2021 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
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0.2100
CY2022 us-gaap Effective Income Tax Rate Reconciliation State And Local Income Taxes
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0.0617
CY2021 us-gaap Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
0.0489
CY2022 us-gaap Effective Income Tax Rate Reconciliation Share Based Compensation Excess Tax Benefit Percent
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0
CY2021 us-gaap Effective Income Tax Rate Reconciliation Share Based Compensation Excess Tax Benefit Percent
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-0.0013
CY2022 us-gaap Effective Income Tax Rate Reconciliation Other Adjustments
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0.0003
CY2021 us-gaap Effective Income Tax Rate Reconciliation Other Adjustments
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0.0002
CY2022 us-gaap Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
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-0.2720
CY2021 us-gaap Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
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CY2022 us-gaap Effective Income Tax Rate Continuing Operations
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0.0000
CY2021 us-gaap Effective Income Tax Rate Continuing Operations
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0.0000
CY2022Q4 us-gaap Deferred Tax Assets Operating Loss Carryforwards
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6890275
CY2021Q4 us-gaap Deferred Tax Assets Operating Loss Carryforwards
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5202047
CY2022Q4 ikt Deferred Tax Assets Capitalized Research And Development
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2854530
CY2021Q4 ikt Deferred Tax Assets Capitalized Research And Development
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0
CY2022Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost
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2440885
CY2021Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost
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2272970
CY2022Q4 ikt Deferred Tax Assets Accrued Expenses
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199961
CY2021Q4 ikt Deferred Tax Assets Accrued Expenses
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12385651
CY2021Q4 us-gaap Deferred Tax Assets Net
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7475017
CY2022Q4 us-gaap Deferred Tax Assets Valuation Allowance
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12385651
CY2021Q4 us-gaap Deferred Tax Assets Valuation Allowance
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7475017
CY2022Q4 us-gaap Deferred Tax Assets Liabilities Net
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0
CY2021Q4 us-gaap Deferred Tax Assets Liabilities Net
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0
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4900000
CY2021 us-gaap Valuation Allowance Deferred Tax Asset Change In Amount
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3800000
CY2022Q4 us-gaap Unrecognized Tax Benefits That Would Impact Effective Tax Rate
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0
CY2021Q4 us-gaap Unrecognized Tax Benefits That Would Impact Effective Tax Rate
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0
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145836
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205451
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56114
CY2022 us-gaap Short Term Lease Payments
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58756
CY2021 us-gaap Short Term Lease Payments
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76816
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145836
CY2022Q4 us-gaap Lessor Operating Lease Payments To Be Received Two Years
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150095
CY2022Q4 us-gaap Lessor Operating Lease Payments To Be Received Three Years
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114966
CY2022Q4 us-gaap Lessor Operating Lease Payments To Be Received
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410897
CY2022Q4 us-gaap Lessee Operating Lease Liability Undiscounted Excess Amount
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59609
CY2022Q4 us-gaap Operating Lease Liability
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351288
CY2022Q4 ikt Potential Milestone Payment Amount
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5625000
CY2022 ikt Individual Retirement Plan Coverage Requirement Minimum Compensation Amount Received During Two Preceding Years
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5000
CY2022 ikt Individual Retirement Plan Coverage Requirement Minimum Compensation Amount Reasonably Expected To Received
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5000
CY2022 us-gaap Defined Contribution Plan Employer Matching Contribution Percent Of Match
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0.03
CY2022 us-gaap Deferred Compensation Arrangement With Individual Contributions By Employer
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48408
CY2021 us-gaap Deferred Compensation Arrangement With Individual Contributions By Employer
DeferredCompensationArrangementWithIndividualContributionsByEmployer
28938

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