| Insider Name | Current Shares | Net Change (1yr) | Buy/Sell Ratio |
|---|---|---|---|
| FELIX BAKER | 4,407,408 | 0 | - |
| JULIAN BAKER | 2,850,385 | 0 | - |
| BROS. ADVISORS LP BAKER | 2,818,039 | +4,147 | ∞ |
| Herve Hoppenot | 326,803 | -236,770 | 0.03 |
| PABLO J CAGNONI | 268,769 | +40,331 | 1.79 |
| PAUL A FRIEDMAN | 256,813 | 0 | - |
| PAUL A BROOKE | 221,911 | 0 | - |
| William Meury | 161,101 | +271,731 | ∞ |
| Christiana Stamoulis | 114,652 | -3,334 | ∞ |
| PAULA J SWAIN | 100,052 | -862 | ∞ |
| Yao Wenqing | 98,575 | 0 | - |
| Steven H Stein | 73,252 | -35,987 | 1.17 |
| Maria E Pasquale | 69,724 | 0 | - |
| Dashyant Dhanak | 58,968 | 0 | - |
| L.P. 14159, | 58,632 | 0 | - |
| Jonathan Elliott Dickinson | 43,723 | 0 | - |
| Vijay K Iyengar | 40,540 | -6,652 | 1.33 |
| Lee Heeson | 38,041 | +11,840 | 5.04 |
| Barry P Flannelly | 35,149 | -24,553 | - |
| Reid M Huber | 34,571 | 0 | - |
| Michael James Morrissey | 34,065 | +12,037 | 3.57 |
| Sheila A. Denton | 26,569 | +65 | 1.33 |
| Paul J Clancy | 23,741 | +3,670 | ∞ |
| EDMUND HARRIGAN | 21,122 | +3,688 | ∞ |
| Eric H. Siegel | 21,053 | 0 | - |
| JEAN JACQUES BIENAIME | 20,841 | +2,518 | ∞ |
| JACQUALYN A FOUSE | 19,326 | +2,518 | ∞ |
| WENDY L DIXON | 17,768 | 0 | - |
| Richard S Levy | 16,926 | 0 | - |
| Brothers Life Sciences LP Baker | 15,000 | 0 | - |
| Matteo Trotta | 14,882 | +13,084 | ∞ |
| Mohamed Khairie Issa | 14,237 | +31,698 | 4.68 |
| Katherine A High | 13,341 | +2,518 | ∞ |
| OTIS W BRAWLEY | 11,252 | +2,518 | ∞ |
| DAVID W GRYSKA | 10,235 | 0 | - |
| Richard A. Hoffman | 9,466 | +9,466 | ∞ |
| David H Gardner | 9,429 | +9,429 | ∞ |
| Susanne Schaffert | 7,389 | +1,669 | ∞ |
| Ramitpal K Basi | 6,506 | +6,506 | ∞ |
| Patrick A Mayes | 4,218 | -3,159 | 0.73 |
| James M Daly | 3,521 | 0 | - |
| Paul Trower | 3,250 | 0 | - |
| Thomas Tray | 2,425 | +1,636 | 1.92 |
| Bros. Advisors (GP) LLC Baker | 0 | 0 | - |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| PABLO J CAGNONI | Apr 21 |
Open Market Sale (S)
Market Sale
|
262,692 | -18,667 | $96.50 | -$1,801,365 |
| PABLO J CAGNONI | Apr 21 |
Option Exercise/Conversion (M)
Compensation/Award
|
268,769 | +6,077 | $64.25 | +$390,447 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| PABLO J CAGNONI | Apr 17 |
Grant/Award Acquisition (A)
Compensation/Award
|
262,692 | +27,892 | $0.00 | +$0 |
| William Meury | Apr 17 |
Option Exercise/Conversion (M)
Compensation/Award
|
161,101 | +125,000 | $0.00 | +$0 |
| Steven H Stein | Apr 17 |
Grant/Award Acquisition (A)
Compensation/Award
|
73,252 | +39,049 | $0.00 | +$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| BROS. ADVISORS LP BAKER | Apr 02 |
Grant/Award Acquisition (A)
Compensation/Award
|
2,818,039 | +421 | $0.00 | +$0 |
| EDMUND HARRIGAN | Apr 02 |
Grant/Award Acquisition (A)
Compensation/Award
|
21,122 | +269 | $94.12 | +$25,318 |
| Paul J Clancy | Apr 02 |
Grant/Award Acquisition (A)
Compensation/Award
|
23,741 | +265 | $94.12 | +$24,941 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Matteo Trotta | Mar 26 |
Tax Payment (F)
Tax Payment
|
14,882 | -537 | $92.23 | -$49,527 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| PABLO J CAGNONI | Mar 19 |
Option Exercise/Conversion (M)
Compensation/Award
|
241,966 | +7,166 | $61.18 | +$438,415 |
| PABLO J CAGNONI | Mar 19 |
Open Market Sale (S)
Market Sale
|
234,800 | -18,667 | $94.24 | -$1,759,178 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| PABLO J CAGNONI | Feb 23 |
Open Market Sale (S)
Market Sale
|
234,800 | -18,668 | $100.91 | -$1,883,787 |
| PABLO J CAGNONI | Feb 23 |
Option Exercise/Conversion (M)
Compensation/Award
|
247,893 | +13,093 | $61.76 | +$808,623 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Lee Heeson | Feb 04 |
Tax Payment (F)
Tax Payment
|
38,041 | -111 | $102.67 | -$11,396 |
| Michael James Morrissey | Feb 04 |
Tax Payment (F)
Tax Payment
|
34,065 | -185 | $102.67 | -$18,993 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Michael James Morrissey | Jan 21 |
Tax Payment (F)
Tax Payment
|
34,250 | -429 | $102.62 | -$44,023 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Patrick A Mayes | Jan 21 |
Grant/Award Acquisition (A)
Compensation/Award
|
4,218 | +4,218 | $0.00 | +$0 |
| Mohamed Khairie Issa | Jan 21 |
Grant/Award Acquisition (A)
Compensation/Award
|
14,237 | +14,237 | $0.00 | +$0 |
| Lee Heeson | Jan 21 |
Grant/Award Acquisition (A)
Compensation/Award
|
38,152 | +8,911 | $0.00 | +$0 |
| Matteo Trotta | Jan 21 |
Grant/Award Acquisition (A)
Compensation/Award
|
8,542 | +8,542 | $0.00 | +$0 |
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