2024 Q3 Form 10-Q Financial Statement

#000095017024093302 Filed on August 08, 2024

View on sec.gov

Income Statement

Concept 2024 Q3 2024 Q2
Revenue $0.00 $35.00M
YoY Change
Cost Of Revenue
YoY Change
Gross Profit
YoY Change
Gross Profit Margin
Selling, General & Admin $12.11M $12.46M
YoY Change -3.87% -7.28%
% of Gross Profit
Research & Development $36.69M $36.71M
YoY Change 19.74% 25.78%
% of Gross Profit
Depreciation & Amortization $302.0K $310.0K
YoY Change 0.67% 37.78%
% of Gross Profit
Operating Expenses $48.80M $49.17M
YoY Change 12.75% 15.36%
Operating Profit -$48.80M -$14.17M
YoY Change 12.75% -66.76%
Interest Expense $8.010M $7.817M
YoY Change 0.13% -2.8%
% of Operating Profit
Other Income/Expense, Net -$3.130M $67.00K
YoY Change -505.97% -79.45%
Pretax Income -$43.12M -$4.867M
YoY Change 29.0% -85.28%
Income Tax $2.243M $2.261M
% Of Pretax Income
Net Earnings -$45.40M -$7.100M
YoY Change 40.99% -79.3%
Net Earnings / Revenue -20.29%
Basic Earnings Per Share -$1.05 -$0.18
Diluted Earnings Per Share -$1.05 -$0.18
COMMON SHARES
Basic Shares Outstanding 36.52M 36.12M
Diluted Shares Outstanding 43.14M 39.70M

Balance Sheet

Concept 2024 Q3 2024 Q2
SHORT-TERM ASSETS
Cash & Short-Term Investments $488.7M $571.3M
YoY Change -18.41% -4.67%
Cash & Equivalents $123.7M $251.1M
Short-Term Investments $365.0M $320.2M
Other Short-Term Assets $13.36M $13.00M
YoY Change -3.17% 11.69%
Inventory
Prepaid Expenses
Receivables $35.00M $35.00M
Other Receivables $7.803M $7.348M
Total Short-Term Assets $544.9M $626.6M
YoY Change -11.99% 1.96%
LONG-TERM ASSETS
Property, Plant & Equipment $5.372M $5.334M
YoY Change 61.32% 109.34%
Goodwill
YoY Change
Intangibles
YoY Change
Long-Term Investments $160.2M $107.8M
YoY Change 249.02% 37.8%
Other Assets $928.0K $788.0K
YoY Change 5.69% -2.96%
Total Long-Term Assets $178.2M $125.2M
YoY Change 204.54% 40.4%
TOTAL ASSETS
Total Short-Term Assets $544.9M $626.6M
Total Long-Term Assets $178.2M $125.2M
Total Assets $723.1M $751.8M
YoY Change 6.7% 6.83%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable $7.154M $11.06M
YoY Change 109.24% 111.5%
Accrued Expenses $943.0K $15.43M
YoY Change -95.72% -27.37%
Deferred Revenue
YoY Change
Short-Term Debt $0.00 $0.00
YoY Change
Long-Term Debt Due
YoY Change
Total Short-Term Liabilities $36.81M $34.67M
YoY Change 30.44% 15.46%
LONG-TERM LIABILITIES
Long-Term Debt $0.00 $0.00
YoY Change
Other Long-Term Liabilities $54.57M $53.31M
YoY Change 6.58% 6.2%
Total Long-Term Liabilities $54.57M $53.31M
YoY Change 6.58% 6.2%
TOTAL LIABILITIES
Total Short-Term Liabilities $36.81M $34.67M
Total Long-Term Liabilities $54.57M $53.31M
Total Liabilities $91.39M $87.97M
YoY Change 15.12% 9.66%
SHAREHOLDERS EQUITY
Retained Earnings $33.90M $79.30M
YoY Change -78.16% -57.68%
Common Stock $37.00K $37.00K
YoY Change 2.78% 2.78%
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity $631.7M $663.9M
YoY Change
Total Liabilities & Shareholders Equity $723.1M $751.8M
YoY Change 6.7% 6.83%

Cashflow Statement

Concept 2024 Q3 2024 Q2
OPERATING ACTIVITIES
Net Income -$45.40M -$7.100M
YoY Change 40.99% -79.3%
Depreciation, Depletion And Amortization $302.0K $310.0K
YoY Change 0.67% 37.78%
Cash From Operating Activities -$37.35M -$33.93M
YoY Change 10.18% 14.83%
INVESTING ACTIVITIES
Capital Expenditures $94.00K $442.0K
YoY Change -89.56% -36.86%
Acquisitions
YoY Change
Other Investing Activities -$91.40M $16.76M
YoY Change -487.27% -19.42%
Cash From Investing Activities -$91.49M $16.32M
YoY Change -503.04% -18.81%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net
YoY Change
Debt Paid & Issued, Net
YoY Change
Cash From Financing Activities -442.0K 122.4M
YoY Change 56035.78%
NET CHANGE
Cash From Operating Activities -37.35M -33.93M
Cash From Investing Activities -91.49M 16.32M
Cash From Financing Activities -442.0K 122.4M
Net Change In Cash -129.3M 104.8M
YoY Change 1054.31% -1235.73%
FREE CASH FLOW
Cash From Operating Activities -$37.35M -$33.93M
Capital Expenditures $94.00K $442.0K
Free Cash Flow -$37.45M -$34.37M
YoY Change 7.6% 13.63%

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CY2024Q2 us-gaap Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
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CY2024Q2 itos Stock Issued During Period Value Employee Stock Purchase Plan And Release Of Restricted Stock Units1
StockIssuedDuringPeriodValueEmployeeStockPurchasePlanAndReleaseOfRestrictedStockUnits1
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CY2024Q2 us-gaap Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
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CY2024Q2 us-gaap Debt Securities Available For Sale Unrealized Gain Loss
DebtSecuritiesAvailableForSaleUnrealizedGainLoss
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CY2024Q2 us-gaap Net Income Loss
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CY2024Q2 us-gaap Stockholders Equity
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us-gaap Profit Loss
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us-gaap Profit Loss
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us-gaap Depreciation And Amortization
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us-gaap Depreciation And Amortization
DepreciationAndAmortization
447000
us-gaap Share Based Compensation
ShareBasedCompensation
15325000
us-gaap Share Based Compensation
ShareBasedCompensation
12771000
itos Net Accretion Of Available For Sale Debt Securities
NetAccretionOfAvailableForSaleDebtSecurities
-5527000
itos Net Accretion Of Available For Sale Debt Securities
NetAccretionOfAvailableForSaleDebtSecurities
-5386000
itos Change In Operating Lease Right Of Use Assets
ChangeInOperatingLeaseRightOfUseAssets
-5000
itos Change In Operating Lease Right Of Use Assets
ChangeInOperatingLeaseRightOfUseAssets
0
itos Increase Decrease In Grants Receivable
IncreaseDecreaseInGrantsReceivable
-397000
itos Increase Decrease In Grants Receivable
IncreaseDecreaseInGrantsReceivable
584000
itos Increase Decrease In Research And Development Tax Credit Receivable
IncreaseDecreaseInResearchAndDevelopmentTaxCreditReceivable
1705000
itos Increase Decrease In Research And Development Tax Credit Receivable
IncreaseDecreaseInResearchAndDevelopmentTaxCreditReceivable
729000
itos Refundable Income Taxes
RefundableIncomeTaxes
140000
itos Refundable Income Taxes
RefundableIncomeTaxes
-1839000
itos Increase Decrease In Milestone Receivable
IncreaseDecreaseInMilestoneReceivable
35000000
us-gaap Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
1051000
us-gaap Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
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us-gaap Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
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us-gaap Increase Decrease In Accounts Payable
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us-gaap Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
5130000
us-gaap Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
989000
us-gaap Increase Decrease In Accrued Income Taxes Payable
IncreaseDecreaseInAccruedIncomeTaxesPayable
0
us-gaap Increase Decrease In Accrued Income Taxes Payable
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us-gaap Increase Decrease In Contract With Customer Liability
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-399000
us-gaap Increase Decrease In Contract With Customer Liability
IncreaseDecreaseInContractWithCustomerLiability
1318000
us-gaap Increase Decrease In Deferred Revenue
IncreaseDecreaseInDeferredRevenue
0
us-gaap Increase Decrease In Deferred Revenue
IncreaseDecreaseInDeferredRevenue
-12595000
itos Increase Decrease In Unrecognized Tax Benefits
IncreaseDecreaseInUnrecognizedTaxBenefits
-2110000
itos Increase Decrease In Unrecognized Tax Benefits
IncreaseDecreaseInUnrecognizedTaxBenefits
-0
us-gaap Net Cash Provided By Used In Operating Activities
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-66327000
us-gaap Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
-56101000
us-gaap Payments To Acquire Investments
PaymentsToAcquireInvestments
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us-gaap Payments To Acquire Investments
PaymentsToAcquireInvestments
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193182000
us-gaap Proceeds From Sale And Maturity Of Marketable Securities
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us-gaap Payments To Acquire Property Plant And Equipment
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us-gaap Payments To Acquire Property Plant And Equipment
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us-gaap Net Cash Provided By Used In Investing Activities
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-53278000
us-gaap Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
-11591000
us-gaap Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
2404000
us-gaap Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
796000
itos Proceeds From Issuance Of Common Stock And Pre Funded Warrants
ProceedsFromIssuanceOfCommonStockAndPreFundedWarrants
119994000
us-gaap Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
122398000
us-gaap Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
796000
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-2843000
us-gaap Effect Of Exchange Rate On Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
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us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
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CY2023Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
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CY2022Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
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CY2024Q2 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
251401000
CY2023Q2 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
216483000
itos Capital Expenditure Included In Accounts Payable
CapitalExpenditureIncludedInAccountsPayable
2000
itos Capital Expenditure Included In Accounts Payable
CapitalExpenditureIncludedInAccountsPayable
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us-gaap Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
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us-gaap Right Of Use Asset Obtained In Exchange For Operating Lease Liability
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us-gaap Other Comprehensive Income Loss Available For Sale Securities Adjustment Before Tax
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-906000
us-gaap Other Comprehensive Income Loss Available For Sale Securities Adjustment Before Tax
OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentBeforeTax
-1620000
itos Offering Costs Included Within Accounts Payable
OfferingCostsIncludedWithinAccountsPayable
277000
itos Offering Costs Included Within Accounts Payable
OfferingCostsIncludedWithinAccountsPayable
0
us-gaap Income Taxes Paid Net
IncomeTaxesPaidNet
2384000
us-gaap Income Taxes Paid Net
IncomeTaxesPaidNet
4321000
CY2024Q2 us-gaap Net Income Loss
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-7100000
us-gaap Net Income Loss
NetIncomeLoss
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CY2024Q2 us-gaap Retained Earnings Accumulated Deficit
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CY2024Q2 us-gaap Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers Net
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0
us-gaap Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers Net
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0
CY2024Q2 us-gaap Available For Sale Debt Securities Amortized Cost Basis
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CY2024Q2 us-gaap Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
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CY2024Q2 us-gaap Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
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CY2024Q2 us-gaap Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
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CY2023Q4 us-gaap Available For Sale Debt Securities Amortized Cost Basis
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CY2023Q4 us-gaap Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
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360000
CY2023Q4 us-gaap Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
325000
CY2023Q4 us-gaap Available For Sale Securities Debt Securities
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CY2024Q2 us-gaap Fair Value Option Aggregate Differences Long Term Debt Instruments
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5000000
CY2024Q2 us-gaap Fair Value Option Aggregate Differences Long Term Debt Instruments
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5000000
CY2024Q2 us-gaap Available For Sale Securities Debt Maturities Within One Year Amortized Cost
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CY2024Q2 us-gaap Available For Sale Securities Debt Maturities Within One Year Fair Value
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CY2024Q2 us-gaap Available For Sale Securities Debt Maturities After One Through Five Years Amortized Cost
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CY2024Q2 us-gaap Available For Sale Securities Debt Maturities After One Through Five Years Fair Value
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CY2024Q2 us-gaap Available For Sale Debt Securities Amortized Cost Basis
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CY2024Q2 us-gaap Available For Sale Securities Debt Securities
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CY2023Q4 us-gaap Available For Sale Securities Debt Maturities Within One Year Amortized Cost
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CY2023Q4 us-gaap Available For Sale Securities Debt Maturities Within One Year Fair Value
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280739000
CY2023Q4 us-gaap Available For Sale Securities Debt Maturities After One Through Five Years Amortized Cost
AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsAmortizedCost
100208000
CY2023Q4 us-gaap Available For Sale Securities Debt Maturities After One Through Five Years Fair Value
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CY2023Q4 us-gaap Available For Sale Debt Securities Amortized Cost Basis
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381243000
CY2023Q4 us-gaap Available For Sale Securities Debt Securities
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us-gaap Proceeds From Sale Of Available For Sale Securities Debt
ProceedsFromSaleOfAvailableForSaleSecuritiesDebt
5600000
CY2023Q2 us-gaap Proceeds From Sale Of Available For Sale Securities Debt
ProceedsFromSaleOfAvailableForSaleSecuritiesDebt
2500000
us-gaap Proceeds From Sale Of Available For Sale Securities Debt
ProceedsFromSaleOfAvailableForSaleSecuritiesDebt
5400000
CY2024Q2 us-gaap Property Plant And Equipment Gross
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CY2023Q4 us-gaap Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
9078000
CY2024Q2 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
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CY2023Q4 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
4382000
CY2024Q2 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
5334000
CY2023Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
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CY2024Q2 us-gaap Depreciation And Amortization
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300000
us-gaap Depreciation And Amortization
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600000
CY2023Q2 us-gaap Depreciation And Amortization
DepreciationAndAmortization
200000
us-gaap Depreciation And Amortization
DepreciationAndAmortization
400000
CY2024Q2 itos Accrued Clinical Trial Costs Current
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14413000
CY2023Q4 itos Accrued Clinical Trial Costs Current
AccruedClinicalTrialCostsCurrent
6956000
CY2024Q2 itos Accrued Professional And Other Fees
AccruedProfessionalAndOtherFees
1018000
CY2023Q4 itos Accrued Professional And Other Fees
AccruedProfessionalAndOtherFees
102000
CY2024Q2 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
15431000
CY2023Q4 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
7058000
itos Upfront Payment Received
UpfrontPaymentReceived
625000000
us-gaap Increase Decrease In Commodity Contract Assets And Liabilities
IncreaseDecreaseInCommodityContractAssetsAndLiabilities
0
us-gaap Research And Development Arrangement With Federal Government Costs Incurred Net
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10500000
itos Percentage Of Royalty On Revenue
PercentageOfRoyaltyOnRevenue
0.30
CY2021 itos Percentage Of Royalty On Revenue
PercentageOfRoyaltyOnRevenue
0.0012
itos Proceeds Received From Grants
ProceedsReceivedFromGrants
777000
itos Proceeds Received From Grants
ProceedsReceivedFromGrants
3121000
itos Grant Income
GrantIncome
1472000
itos Grant Income
GrantIncome
1534000
CY2024Q2 us-gaap Grants Receivable Current
GrantsReceivableCurrent
393000
CY2023Q2 us-gaap Grants Receivable Current
GrantsReceivableCurrent
0
CY2024Q2 us-gaap Deferred Income Noncurrent
DeferredIncomeNoncurrent
6628000
CY2023Q2 us-gaap Deferred Income Noncurrent
DeferredIncomeNoncurrent
6813000
us-gaap Common Stock Voting Rights
CommonStockVotingRights
Each share of common stock entitles the holders to one vote on all matters submitted to a vote of the Company’s stockholders.
CY2024Q2 us-gaap Proceeds From Issuance Or Sale Of Equity
ProceedsFromIssuanceOrSaleOfEquity
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CY2024Q2 itos Offering Cost Incurred
OfferingCostIncurred
300000
CY2024Q2 us-gaap Adjustments To Additional Paid In Capital Stock Issued Ownshare Lending Arrangement Issuance Costs
AdjustmentsToAdditionalPaidInCapitalStockIssuedOwnshareLendingArrangementIssuanceCosts
20000000
us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Award Vesting Rights Percentage
SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage
0.25
us-gaap Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Period1
ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1
P36M
CY2024Q2 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
8062000
CY2023Q2 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
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us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
15325000
us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
12771000
CY2024Q2 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
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us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
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CY2023Q2 us-gaap Allocated Share Based Compensation Expense
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us-gaap Allocated Share Based Compensation Expense
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CY2023Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
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ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
17.73
CY2023 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
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us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
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us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
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us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
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us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
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us-gaap Stock Issued During Period Shares Stock Options Exercised
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us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
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CY2024Q2 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
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CY2024Q2 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
16.44
us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
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CY2024Q2 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
29754000
CY2024Q2 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber
5366265
CY2024Q2 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice
16.66
us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1
P5Y10M24D
CY2024Q2 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1
21573000
us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
8.7
us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
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CY2024Q2 us-gaap Income Loss From Continuing Operations Before Income Taxes Domestic
IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic
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CY2023Q2 us-gaap Income Loss From Continuing Operations Before Income Taxes Domestic
IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic
-14868000
us-gaap Income Loss From Continuing Operations Before Income Taxes Domestic
IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic
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us-gaap Income Loss From Continuing Operations Before Income Taxes Domestic
IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic
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CY2024Q2 us-gaap Income Loss From Continuing Operations Before Income Taxes Foreign
IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign
17862000
CY2023Q2 us-gaap Income Loss From Continuing Operations Before Income Taxes Foreign
IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign
-18200000
us-gaap Income Loss From Continuing Operations Before Income Taxes Foreign
IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign
1939000
us-gaap Income Loss From Continuing Operations Before Income Taxes Foreign
IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign
-11236000
CY2024Q2 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
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CY2023Q2 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
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us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
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us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
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CY2024Q2 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
2261000
CY2023Q2 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
1232000
us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
4475000
us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
2431000
CY2024Q2 us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
-0.464
CY2023Q2 us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
-0.037
us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
-0.109
us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
-0.051
CY2024Q2 us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
-0.464
us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
-0.109
CY2024Q2 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
0.21
us-gaap Effective Income Tax Rate Reconciliation Tax Credits Foreign
EffectiveIncomeTaxRateReconciliationTaxCreditsForeign
0.25
CY2024Q2 itos Liability For Accrual Of Additional Interest Expense
LiabilityForAccrualOfAdditionalInterestExpense
1000000
itos Liability For Accrual Of Additional Interest Expense
LiabilityForAccrualOfAdditionalInterestExpense
2100000
CY2024Q2 us-gaap Unrecognized Tax Benefits Interest On Income Taxes Accrued
UnrecognizedTaxBenefitsInterestOnIncomeTaxesAccrued
6000000
CY2023Q2 us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
-0.037
us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
-0.051
CY2023Q2 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
0.21
us-gaap Effective Income Tax Rate Reconciliation Tax Credits Foreign
EffectiveIncomeTaxRateReconciliationTaxCreditsForeign
0.25
CY2024Q2 us-gaap Land Subject To Ground Leases
LandSubjectToGroundLeases
1577
us-gaap Other Commitments Description
OtherCommitmentsDescription
In January 2021, the Company entered into an amendment to extend the lease, effective February 2021 with a termination date of January 2030, and increase the office and laboratory space
CY2024Q2 itos Operating Leases Rent Expense Net1
OperatingLeasesRentExpenseNet1
400000
itos Operating Leases Rent Expense Net1
OperatingLeasesRentExpenseNet1
800000
CY2023Q2 itos Operating Leases Rent Expense Net1
OperatingLeasesRentExpenseNet1
300000
itos Operating Leases Rent Expense Net1
OperatingLeasesRentExpenseNet1
600000
CY2024Q2 us-gaap Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
P4Y2M12D
CY2023Q4 us-gaap Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
P4Y7M6D
CY2024Q2 us-gaap Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
0.0474
CY2023Q4 us-gaap Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
0.0475
CY2024Q2 us-gaap Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
73000
CY2023Q2 us-gaap Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
981000
us-gaap Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
235000
us-gaap Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
1059000
CY2024Q2 us-gaap Operating Lease Payments
OperatingLeasePayments
421000
CY2023Q2 us-gaap Operating Lease Payments
OperatingLeasePayments
278000
us-gaap Operating Lease Payments
OperatingLeasePayments
768000
us-gaap Operating Lease Payments
OperatingLeasePayments
549000
CY2024Q2 us-gaap Lessee Operating Lease Liability Payments Remainder Of Fiscal Year
LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear
754000
CY2024Q2 us-gaap Lessee Operating Lease Liability Payments Due Next Twelve Months
LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
1503000
CY2024Q2 us-gaap Lessee Operating Lease Liability Payments Due Year Two
LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
1467000
CY2024Q2 us-gaap Lessee Operating Lease Liability Payments Due Year Three
LesseeOperatingLeaseLiabilityPaymentsDueYearThree
968000
CY2024Q2 us-gaap Lessee Operating Lease Liability Payments Due Year Four
LesseeOperatingLeaseLiabilityPaymentsDueYearFour
786000
CY2024Q2 itos Lessee Operating Lease Liability Payments Due After Year Four
LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFour
580000
CY2024Q2 us-gaap Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
6058000
CY2024Q2 us-gaap Lessee Operating Lease Liability Undiscounted Excess Amount
LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
542000
CY2024Q2 us-gaap Operating Lease Liability
OperatingLeaseLiability
5516000
CY2024Q2 us-gaap Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
1277000
CY2024Q2 us-gaap Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
4239000
CY2024Q2 us-gaap Income Loss From Continuing Operations
IncomeLossFromContinuingOperations
-7128000
CY2023Q2 us-gaap Income Loss From Continuing Operations
IncomeLossFromContinuingOperations
-34300000
us-gaap Income Loss From Continuing Operations
IncomeLossFromContinuingOperations
-45344000
us-gaap Income Loss From Continuing Operations
IncomeLossFromContinuingOperations
-49851000
CY2024Q2 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
39699053
CY2023Q2 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
35768952
us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
37771084
us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
35742641
CY2024Q2 us-gaap Incremental Common Shares Attributable To Share Based Payment Arrangements
IncrementalCommonSharesAttributableToShareBasedPaymentArrangements
0
CY2023Q2 us-gaap Incremental Common Shares Attributable To Share Based Payment Arrangements
IncrementalCommonSharesAttributableToShareBasedPaymentArrangements
0
us-gaap Incremental Common Shares Attributable To Share Based Payment Arrangements
IncrementalCommonSharesAttributableToShareBasedPaymentArrangements
0
us-gaap Incremental Common Shares Attributable To Share Based Payment Arrangements
IncrementalCommonSharesAttributableToShareBasedPaymentArrangements
0
CY2024Q2 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
39699053
CY2023Q2 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
35768952
us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
37771084
us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
35742641
CY2024Q2 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.18
CY2023Q2 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.96
us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-1.2
us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-1.39
CY2024Q2 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.18
CY2023Q2 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.96
us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-1.2
us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-1.39
CY2024Q2 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
1884542
us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
2028359
CY2023Q2 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
1705906
us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
1790788

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