| Insider Name | Current Shares | Net Change (1yr) | Buy/Sell Ratio |
|---|---|---|---|
| BRIDGE VENTURE PARTNERS V-B LP NORTH | 2,259,301 | 0 | - |
| ADVISORS LLC PERCEPTIVE | 1,309,115 | 0 | - |
| Maria Palasis | 1,094,733 | -1,600 | 1.12 |
| Venture Management Co. V, L.L.C. Polaris | 1,062,259 | 0 | - |
| GP, LLC NBVM | 778,592 | 0 | - |
| Jason Cavalier | 517,880 | -2,120 | - |
| Venture Management Co IV LLC Polaris | 316,980 | 0 | - |
| Richard Nieman | 200,000 | 0 | - |
| John E Bishop | 200,000 | 0 | - |
| Guy Levy | 155,000 | 0 | - |
| JOSEPH EDELMAN | 124,859 | -104,523 | - |
| Carmichael Roberts | 58,414 | 0 | - |
| GEORGE M WHITESIDES | 55,064 | 0 | - |
| R Don Elsey | 45,000 | 0 | - |
| Corinne Noyes | 36,667 | 0 | - |
| nancy lynn MD snyderman | 32,000 | 0 | - |
| JAMES R TOBIN | 32,000 | 0 | - |
| W Bradford Smith | 32,000 | 0 | - |
| C ANN MERRIFIELD | 32,000 | 0 | - |
| Pamela E. Nelson | 30,000 | 0 | - |
| MICHAEL SETH ALTMAN | 30,000 | 0 | - |
| Konstantin Poukalov | 30,000 | 0 | - |
| Robert E. Richard | 30,000 | 0 | - |
| Laura Edgerly-Pflug | 20,046 | 0 | - |
| EDWARD T ANDERSON | 20,000 | 0 | - |
| ROBERT LANGER | 15,167 | 0 | - |
| Harlan Waksal | 0 | 0 | - |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Maria Palasis | Apr 03 |
Disposition to Issuer (D)
Payment to Issuer
|
1,094,733 | -2,000 | $0.00 | -$0 |
| Jason Cavalier | Apr 03 |
Disposition to Issuer (D)
Payment to Issuer
|
517,880 | -667 | $0.00 | -$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Jason Cavalier | Jan 08 |
Open Market Sale (S)
Market Sale
|
518,547 | -769 | $3.36 | -$2,586 |
| Maria Palasis | Jan 08 |
Open Market Sale (S)
Market Sale
|
1,096,733 | -1,702 | $3.36 | -$5,725 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| JOSEPH EDELMAN | Nov 13 |
Open Market Sale (S)
Market Sale
|
124,859 | -28,597 | $3.90 | -$111,531 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| JOSEPH EDELMAN | Nov 13 |
Open Market Sale (S)
Market Sale
|
153,456 | -7,862 | $4.06 | -$31,915 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| JOSEPH EDELMAN | Nov 13 |
Open Market Sale (S)
Market Sale
|
161,318 | -4,783 | $4.31 | -$20,636 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| JOSEPH EDELMAN | Nov 10 |
Open Market Sale (S)
Market Sale
|
166,101 | -16,633 | $4.54 | -$75,510 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| JOSEPH EDELMAN | Nov 10 |
Open Market Sale (S)
Market Sale
|
182,734 | -17,746 | $4.75 | -$84,234 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| JOSEPH EDELMAN | Nov 10 |
Open Market Sale (S)
Market Sale
|
200,480 | -28,902 | $5.18 | -$149,709 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Maria Palasis | Oct 03 |
Grant/Award Acquisition (A)
Compensation/Award
|
7,333 | +3,667 | $0.00 | +$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Maria Palasis | Jul 14 |
Open Market Sale (S)
Market Sale
|
1,098,435 | -1,565 | $8.91 | -$13,944 |
| Jason Cavalier | Jul 14 |
Open Market Sale (S)
Market Sale
|
519,316 | -684 | $8.91 | -$6,094 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| C ANN MERRIFIELD | May 16 |
Grant/Award Acquisition (A)
Compensation/Award
|
32,000 | +32,000 | $0.00 | +$0 |
| nancy lynn MD snyderman | May 16 |
Grant/Award Acquisition (A)
Compensation/Award
|
32,000 | +32,000 | $0.00 | +$0 |
| W Bradford Smith | May 16 |
Grant/Award Acquisition (A)
Compensation/Award
|
32,000 | +32,000 | $0.00 | +$0 |
| JAMES R TOBIN | May 16 |
Grant/Award Acquisition (A)
Compensation/Award
|
32,000 | +32,000 | $0.00 | +$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Maria Palasis | Jan 10 |
Grant/Award Acquisition (A)
Compensation/Award
|
1,100,000 | +800,000 | $0.00 | +$0 |
| Jason Cavalier | Jan 10 |
Grant/Award Acquisition (A)
Compensation/Award
|
520,000 | +420,000 | $0.00 | +$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Harlan Waksal | Dec 11 |
Grant/Award Acquisition (A)
Compensation/Award
|
0 | -128,333 | $0.00 | -$0 |
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