2016 Q1 Form 10-K Financial Statement

#000156459016014692 Filed on March 14, 2016

View on sec.gov

Income Statement

Concept 2016 Q1 2015 2014 Q4
Revenue $2.710M $0.00 $0.00
YoY Change
Cost Of Revenue
YoY Change
Gross Profit
YoY Change
Gross Profit Margin
Selling, General & Admin $7.210M $16.76M $2.150M
YoY Change 176.25% 284.4% 451.28%
% of Gross Profit
Research & Development $15.42M $38.10M $5.060M
YoY Change 177.22% 255.43% 232.89%
% of Gross Profit
Depreciation & Amortization $386.0K $728.0K $100.0K
YoY Change 319.57% 283.16%
% of Gross Profit
Operating Expenses $22.63M $54.86M $7.213M
YoY Change 177.04% 263.72% 277.64%
Operating Profit -$19.92M -$54.86M -$7.213M
YoY Change 143.86% 263.72%
Interest Expense $270.0K $630.0K -$910.0K
YoY Change 28.57% -144.37% 9000.0%
% of Operating Profit
Other Income/Expense, Net $212.0K $76.00K -$60.00K
YoY Change 8.16% -104.67% 50.0%
Pretax Income -$19.70M -$54.78M -$8.180M
YoY Change 147.18% 227.83% 319.49%
Income Tax $0.00 $0.00 $0.00
% Of Pretax Income
Net Earnings -$19.70M -$54.78M -$8.182M
YoY Change 147.2% 227.85% 319.59%
Net Earnings / Revenue -727.08%
Basic Earnings Per Share
Diluted Earnings Per Share -$502.7K -$2.328M -$216.2K
COMMON SHARES
Basic Shares Outstanding 39.19M
Diluted Shares Outstanding

Balance Sheet

Concept 2016 Q1 2015 2014 Q4
SHORT-TERM ASSETS
Cash & Short-Term Investments $303.3M $205.1M $114.2M
YoY Change 190.8% 79.6%
Cash & Equivalents $193.2M $73.90M $114.2M
Short-Term Investments $110.1M $131.1M $0.00
Other Short-Term Assets $3.600M $2.500M $100.0K
YoY Change 350.0% 2400.0%
Inventory
Prepaid Expenses
Receivables
Other Receivables
Total Short-Term Assets $306.8M $207.6M $114.2M
YoY Change 191.91% 81.79%
LONG-TERM ASSETS
Property, Plant & Equipment $16.10M $7.800M $1.264M
YoY Change 1138.46% 500.0%
Goodwill
YoY Change
Intangibles
YoY Change
Long-Term Investments
YoY Change
Other Assets $1.500M $1.500M $1.800M
YoY Change -31.82% -16.67%
Total Long-Term Assets $17.70M $9.300M $3.102M
YoY Change 405.71% 200.0%
TOTAL ASSETS
Total Short-Term Assets $306.8M $207.6M $114.2M
Total Long-Term Assets $17.70M $9.300M $3.102M
Total Assets $324.5M $216.9M $117.3M
YoY Change 198.8% 84.91%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable $5.800M $5.400M $2.166M
YoY Change 427.27% 145.45%
Accrued Expenses $1.200M $2.800M $500.0K
YoY Change 300.0% 460.0%
Deferred Revenue
YoY Change
Short-Term Debt $0.00 $0.00 $0.00
YoY Change
Long-Term Debt Due $0.00 $1.200M
YoY Change -100.0%
Total Short-Term Liabilities $24.82M $10.90M $5.103M
YoY Change 630.06% 113.73%
LONG-TERM LIABILITIES
Long-Term Debt $0.00 $0.00 $1.300M
YoY Change -100.0% -100.0%
Other Long-Term Liabilities $109.8M $600.0K $1.600M
YoY Change 7742.86% -62.5%
Total Long-Term Liabilities $109.8M $600.0K $2.900M
YoY Change 4475.0% -79.31%
TOTAL LIABILITIES
Total Short-Term Liabilities $24.82M $10.90M $5.103M
Total Long-Term Liabilities $109.8M $600.0K $2.900M
Total Liabilities $134.6M $11.50M $7.989M
YoY Change 2221.36% 43.75%
SHAREHOLDERS EQUITY
Retained Earnings -$102.3M -$27.83M
YoY Change
Common Stock $292.0M $1.111M
YoY Change
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity $189.8M $205.4M -$26.72M
YoY Change
Total Liabilities & Shareholders Equity $324.5M $216.9M $117.3M
YoY Change 198.77% 84.91%

Cashflow Statement

Concept 2016 Q1 2015 2014 Q4
OPERATING ACTIVITIES
Net Income -$19.70M -$54.78M -$8.182M
YoY Change 147.2% 227.85% 319.59%
Depreciation, Depletion And Amortization $386.0K $728.0K $100.0K
YoY Change 319.57% 283.16%
Cash From Operating Activities $101.4M -$40.84M -$4.200M
YoY Change -1321.69% 294.21% 162.5%
INVESTING ACTIVITIES
Capital Expenditures $3.400M $4.362M -$400.0K
YoY Change 1488.79% 335.76% 300.0%
Acquisitions
YoY Change
Other Investing Activities $21.10M -$132.8M $0.00
YoY Change -135.58% 132670.0%
Cash From Investing Activities $17.70M -$137.1M -$400.0K
YoY Change -129.75% 12366.36%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net $143.0M
YoY Change
Debt Paid & Issued, Net
YoY Change
Cash From Financing Activities 200.0K 137.7M 111.6M
YoY Change -115.38% 11.08%
NET CHANGE
Cash From Operating Activities 101.4M -40.84M -4.200M
Cash From Investing Activities 17.70M -137.1M -400.0K
Cash From Financing Activities 200.0K 137.7M 111.6M
Net Change In Cash 119.3M -40.24M 107.0M
YoY Change -272.65% -135.76% -6787.5%
FREE CASH FLOW
Cash From Operating Activities $101.4M -$40.84M -$4.200M
Capital Expenditures $3.400M $4.362M -$400.0K
Free Cash Flow $98.00M -$45.20M -$3.800M
YoY Change -1251.05% 297.87% 153.33%

Facts In Submission

Frame Concept Type Concept / XBRL Key Value Unit
CY2015 dei Document Fiscal Year Focus
DocumentFiscalYearFocus
2015
CY2015Q4 us-gaap Short Term Investments
ShortTermInvestments
131149000
CY2014Q4 us-gaap Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
58000
CY2014Q4 us-gaap Assets Current
AssetsCurrent
114243000
CY2016Q1 dei Entity Common Stock Shares Outstanding
EntityCommonStockSharesOutstanding
39187017
CY2015Q2 dei Entity Public Float
EntityPublicFloat
422395134
CY2015Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
73933000
CY2014Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
114185000
CY2014Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
1264000
CY2015Q4 us-gaap Accrued Liabilities And Other Liabilities
AccruedLiabilitiesAndOtherLiabilities
5523000
CY2014Q4 us-gaap Accrued Liabilities And Other Liabilities
AccruedLiabilitiesAndOtherLiabilities
1737000
CY2014Q4 us-gaap Liabilities Current
LiabilitiesCurrent
5103000
CY2015 dei Document Type
DocumentType
10-K
CY2015 dei Amendment Flag
AmendmentFlag
false
CY2015 dei Document Period End Date
DocumentPeriodEndDate
2015-12-31
CY2015 dei Document Fiscal Period Focus
DocumentFiscalPeriodFocus
FY
CY2015 dei Entity Central Index Key
EntityCentralIndexKey
0001609809
CY2014Q4 us-gaap Commitments And Contingencies
CommitmentsAndContingencies
CY2014Q4 us-gaap Additional Paid In Capital Common Stock
AdditionalPaidInCapitalCommonStock
1104000
CY2015Q4 us-gaap Liabilities
Liabilities
11506000
CY2014Q4 us-gaap Common Stock Value
CommonStockValue
7000
CY2015Q4 us-gaap Commitments And Contingencies
CommitmentsAndContingencies
CY2015 dei Entity Registrant Name
EntityRegistrantName
Seres Therapeutics, Inc.
CY2015Q4 us-gaap Assets Current
AssetsCurrent
207610000
CY2015Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
7751000
CY2015Q4 us-gaap Assets
Assets
216900000
CY2014Q4 us-gaap Assets
Assets
117345000
CY2015Q4 us-gaap Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
2528000
CY2015Q4 us-gaap Accounts Payable Current
AccountsPayableCurrent
5397000
CY2015 dei Current Fiscal Year End Date
CurrentFiscalYearEndDate
--12-31
CY2015 dei Entity Well Known Seasoned Issuer
EntityWellKnownSeasonedIssuer
Yes
CY2015 dei Entity Current Reporting Status
EntityCurrentReportingStatus
Yes
CY2015 dei Entity Voluntary Filers
EntityVoluntaryFilers
No
CY2015 dei Entity Filer Category
EntityFilerCategory
Non-accelerated Filer
CY2015 us-gaap Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
-2.33
CY2014 us-gaap Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
-2.67
CY2015 us-gaap Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
23532400
CY2015Q4 us-gaap Common Stock Shares Outstanding
CommonStockSharesOutstanding
39082017
CY2015Q4 us-gaap Common Stock Shares Authorized
CommonStockSharesAuthorized
200000000
CY2015Q4 us-gaap Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
0.001
CY2014Q4 us-gaap Common Stock Shares Outstanding
CommonStockSharesOutstanding
6890250
CY2014Q4 us-gaap Common Stock Shares Authorized
CommonStockSharesAuthorized
38000000
CY2015Q4 us-gaap Common Stock Shares Issued
CommonStockSharesIssued
39082017
CY2014Q4 us-gaap Common Stock Shares Issued
CommonStockSharesIssued
6890250
CY2014Q4 us-gaap Liabilities
Liabilities
7989000
CY2014Q4 us-gaap Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
0.001
CY2014 us-gaap General And Administrative Expense
GeneralAndAdministrativeExpense
4364000
CY2015 us-gaap Research And Development Expense
ResearchAndDevelopmentExpense
38095000
CY2015 dei Trading Symbol
TradingSymbol
MCRB
CY2014 us-gaap Research And Development Expense
ResearchAndDevelopmentExpense
10718000
CY2013 us-gaap Research And Development Expense
ResearchAndDevelopmentExpense
4805000
CY2013 us-gaap General And Administrative Expense
GeneralAndAdministrativeExpense
1247000
CY2013 us-gaap Operating Expenses
OperatingExpenses
6052000
CY2015Q4 us-gaap Liabilities Current
LiabilitiesCurrent
10920000
CY2015Q4 mcrb Lease Incentive Payable Noncurrent
LeaseIncentivePayableNoncurrent
586000
CY2015 us-gaap Other Comprehensive Income Loss Available For Sale Securities Adjustment Before Reclassification Adjustments Net Of Tax
OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentBeforeReclassificationAdjustmentsNetOfTax
30000
CY2015Q4 us-gaap Additional Paid In Capital Common Stock
AdditionalPaidInCapitalCommonStock
287937000
CY2015Q4 us-gaap Restricted Cash And Cash Equivalents Noncurrent
RestrictedCashAndCashEquivalentsNoncurrent
1539000
CY2015Q4 us-gaap Common Stock Value
CommonStockValue
39000
CY2015Q4 us-gaap Accumulated Other Comprehensive Income Loss Net Of Tax
AccumulatedOtherComprehensiveIncomeLossNetOfTax
30000
CY2015Q4 us-gaap Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
-82612000
CY2014Q4 us-gaap Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
-27832000
CY2015Q4 us-gaap Stockholders Equity
StockholdersEquity
205394000
CY2014Q4 us-gaap Stockholders Equity
StockholdersEquity
-26721000
CY2015Q4 us-gaap Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
216900000
CY2014Q4 us-gaap Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
117345000
CY2014 us-gaap Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
5000
CY2013 us-gaap Operating Income Loss
OperatingIncomeLoss
-6052000
CY2014 us-gaap Share Based Compensation
ShareBasedCompensation
2068000
CY2013 us-gaap Share Based Compensation
ShareBasedCompensation
209000
CY2014 us-gaap Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
190000
CY2013 us-gaap Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
88000
CY2015 us-gaap Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
2470000
CY2014 us-gaap Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
810000
CY2013 us-gaap Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
281000
CY2014 us-gaap Increase Decrease In Accrued Liabilities And Other Operating Liabilities
IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities
1474000
CY2013 us-gaap Increase Decrease In Accrued Liabilities And Other Operating Liabilities
IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities
197000
CY2013 us-gaap Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
6394916
CY2013 us-gaap Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
-1.09
CY2015 us-gaap Operating Expenses
OperatingExpenses
54856000
CY2015 us-gaap Operating Income Loss
OperatingIncomeLoss
-54856000
CY2014 us-gaap Operating Income Loss
OperatingIncomeLoss
-15082000
CY2015 us-gaap Fair Value Option Changes In Fair Value Gain Loss1
FairValueOptionChangesInFairValueGainLoss1
-7000
CY2014 us-gaap Fair Value Option Changes In Fair Value Gain Loss1
FairValueOptionChangesInFairValueGainLoss1
-1418000
CY2015 us-gaap Nonoperating Income Expense
NonoperatingIncomeExpense
76000
CY2014 us-gaap Nonoperating Income Expense
NonoperatingIncomeExpense
-1627000
CY2015 us-gaap Net Income Loss
NetIncomeLoss
-54780000
CY2014 us-gaap Net Income Loss
NetIncomeLoss
-16709000
CY2014 us-gaap Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
1001000
CY2013 us-gaap Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
174000
CY2015 us-gaap Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
262000
CY2014 us-gaap Increase Decrease In Restricted Cash
IncreaseDecreaseInRestrictedCash
102000
CY2015 dei Entity Incorporation Date Of Incorporation
EntityIncorporationDateOfIncorporation
2010-10-31
CY2015 dei Entity Incorporation State Country Name
EntityIncorporationStateCountryName
State of Delaware
CY2013 us-gaap Temporary Equity Accretion To Redemption Value Adjustment
TemporaryEquityAccretionToRedemptionValueAdjustment
875000
CY2014Q4 us-gaap Restricted Cash And Cash Equivalents Noncurrent
RestrictedCashAndCashEquivalentsNoncurrent
139000
CY2014Q4 mcrb Deferred Offering Costs Non Current
DeferredOfferingCostsNonCurrent
1684000
CY2014Q4 us-gaap Deferred Finance Costs Noncurrent Net
DeferredFinanceCostsNoncurrentNet
15000
CY2014Q4 us-gaap Accounts Payable Current
AccountsPayableCurrent
2166000
CY2014Q4 us-gaap Long Term Notes Payable
LongTermNotesPayable
1304000
CY2014Q4 mcrb Preferred Stock Warrant Liability
PreferredStockWarrantLiability
1582000
CY2015 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
0
CY2015 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
-0.340
CY2015 us-gaap Effective Income Tax Rate Reconciliation Tax Credits Research
EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
0.057
CY2015 us-gaap Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
-0.053
CY2015 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
0.041
CY2015 us-gaap Effective Income Tax Rate Reconciliation Other Reconciling Items Percent
EffectiveIncomeTaxRateReconciliationOtherReconcilingItemsPercent
0.003
CY2015 us-gaap Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
0.406
CY2014 us-gaap Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
0.373
CY2015 us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
0.00
CY2014 us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
0.00
CY2014Q4 us-gaap Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
7946000
CY2015Q4 us-gaap Deferred Tax Assets Tax Credit Carryforwards Research
DeferredTaxAssetsTaxCreditCarryforwardsResearch
4180000
CY2014Q4 us-gaap Deferred Tax Assets Tax Credit Carryforwards Research
DeferredTaxAssetsTaxCreditCarryforwardsResearch
1055000
CY2015Q4 mcrb Deferred Tax Assets Capitalized Organization Costs
DeferredTaxAssetsCapitalizedOrganizationCosts
527000
CY2014Q4 mcrb Deferred Tax Assets Capitalized Organization Costs
DeferredTaxAssetsCapitalizedOrganizationCosts
571000
CY2015Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost
1897000
CY2014Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost
436000
CY2015Q4 us-gaap Deferred Tax Assets Charitable Contribution Carryforwards
DeferredTaxAssetsCharitableContributionCarryforwards
5000
CY2014Q4 us-gaap Notes Payable Current
NotesPayableCurrent
1200000
CY2015 us-gaap General And Administrative Expense
GeneralAndAdministrativeExpense
16761000
CY2014 us-gaap Operating Expenses
OperatingExpenses
15082000
CY2015 us-gaap Interest Income Other
InterestIncomeOther
638000
CY2015 us-gaap Interest Expense Other
InterestExpenseOther
555000
CY2014 us-gaap Interest Expense Other
InterestExpenseOther
209000
CY2013 us-gaap Interest Expense Other
InterestExpenseOther
42000
CY2013 us-gaap Fair Value Option Changes In Fair Value Gain Loss1
FairValueOptionChangesInFairValueGainLoss1
-8000
CY2013 us-gaap Nonoperating Income Expense
NonoperatingIncomeExpense
-50000
CY2013 us-gaap Net Income Loss
NetIncomeLoss
-6102000
CY2014 us-gaap Temporary Equity Accretion To Redemption Value Adjustment
TemporaryEquityAccretionToRedemptionValueAdjustment
1291000
CY2015 us-gaap Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
-54780000
CY2014 us-gaap Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
-18000000
CY2013 us-gaap Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
-6977000
CY2014 us-gaap Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
6748037
CY2015 us-gaap Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
30000
CY2015 us-gaap Other Comprehensive Income Loss Net Of Tax
OtherComprehensiveIncomeLossNetOfTax
30000
CY2015 us-gaap Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
-54750000
CY2014 us-gaap Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
-18000000
CY2013 us-gaap Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
-6977000
CY2015 us-gaap Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodTax
0
CY2014 us-gaap Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodTax
0
CY2013 us-gaap Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodTax
0
CY2012Q4 us-gaap Stockholders Equity
StockholdersEquity
-4348000
CY2013 us-gaap Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
209000
CY2013 us-gaap Temporary Equity Accretion To Redemption Value
TemporaryEquityAccretionToRedemptionValue
-875000
CY2013Q4 us-gaap Stockholders Equity
StockholdersEquity
-11116000
CY2014 us-gaap Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
5000
CY2014 us-gaap Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
5000
CY2014 mcrb Stock Issued During Period Value Common Stock Warrants Exercised
StockIssuedDuringPeriodValueCommonStockWarrantsExercised
317000
CY2014 us-gaap Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
2068000
CY2014 us-gaap Temporary Equity Accretion To Redemption Value
TemporaryEquityAccretionToRedemptionValue
-1291000
CY2015 us-gaap Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
93000
CY2015 mcrb Stock Issued During Period Value Common Stock Warrants Exercised
StockIssuedDuringPeriodValueCommonStockWarrantsExercised
169000
CY2015 us-gaap Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
139267000
CY2015 us-gaap Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
9694000
CY2015 us-gaap Adjustments To Additional Paid In Capital Warrant Issued
AdjustmentsToAdditionalPaidInCapitalWarrantIssued
1589000
CY2015 us-gaap Stock Issued During Period Value Conversion Of Convertible Securities
StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
136053000
CY2015 us-gaap Share Based Compensation
ShareBasedCompensation
9694000
CY2015 us-gaap Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
728000
CY2015 us-gaap Fair Value Adjustment Of Warrants
FairValueAdjustmentOfWarrants
7000
CY2014 us-gaap Fair Value Adjustment Of Warrants
FairValueAdjustmentOfWarrants
1418000
CY2013 us-gaap Fair Value Adjustment Of Warrants
FairValueAdjustmentOfWarrants
8000
CY2014 mcrb Payment Of License Fees In Common Stock Warrant
PaymentOfLicenseFeesInCommonStockWarrant
317000
CY2015 us-gaap Other Noncash Expense
OtherNoncashExpense
367000
CY2014 us-gaap Other Noncash Expense
OtherNoncashExpense
81000
CY2013 us-gaap Other Noncash Expense
OtherNoncashExpense
19000
CY2014 us-gaap Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
7000
CY2013 us-gaap Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
21000
CY2015 us-gaap Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
2682000
CY2015 us-gaap Increase Decrease In Accrued Liabilities And Other Operating Liabilities
IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities
2928000
CY2015 us-gaap Net Cash Provided By Used In Operating Activities Continuing Operations
NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
-40844000
CY2014 us-gaap Net Cash Provided By Used In Operating Activities Continuing Operations
NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
-10358000
CY2013 us-gaap Net Cash Provided By Used In Operating Activities Continuing Operations
NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
-5321000
CY2015 us-gaap Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
4362000
CY2014Q4 us-gaap Operating Expenses
OperatingExpenses
7213000
CY2014Q4 us-gaap Operating Income Loss
OperatingIncomeLoss
-7213000
CY2014Q4 us-gaap Net Income Loss
NetIncomeLoss
-8182000
CY2014Q4 us-gaap Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
-1.24
CY2015 us-gaap Payments To Acquire Short Term Investments
PaymentsToAcquireShortTermInvestments
267761000
CY2015 us-gaap Proceeds From Sale Maturity And Collections Of Investments
ProceedsFromSaleMaturityAndCollectionsOfInvestments
136390000
CY2015 us-gaap Increase Decrease In Restricted Cash
IncreaseDecreaseInRestrictedCash
1400000
CY2013 us-gaap Increase Decrease In Restricted Cash
IncreaseDecreaseInRestrictedCash
10000
CY2015 us-gaap Net Cash Provided By Used In Investing Activities Continuing Operations
NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
-137133000
CY2014 us-gaap Net Cash Provided By Used In Investing Activities Continuing Operations
NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
-1103000
CY2013 us-gaap Net Cash Provided By Used In Investing Activities Continuing Operations
NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
-184000
CY2015 mcrb Proceeds From Issuance Of Convertible Preferred Stock Net Of Issuance Costs
ProceedsFromIssuanceOfConvertiblePreferredStockNetOfIssuanceCosts
-24000
CY2014 mcrb Proceeds From Issuance Of Convertible Preferred Stock Net Of Issuance Costs
ProceedsFromIssuanceOfConvertiblePreferredStockNetOfIssuanceCosts
123203000
CY2014 mcrb Proceeds From Issuance Of Notes Payable And Preferred Stock Warrants Net Of Issuance Costs
ProceedsFromIssuanceOfNotesPayableAndPreferredStockWarrantsNetOfIssuanceCosts
2000000
CY2013 mcrb Proceeds From Issuance Of Notes Payable And Preferred Stock Warrants Net Of Issuance Costs
ProceedsFromIssuanceOfNotesPayableAndPreferredStockWarrantsNetOfIssuanceCosts
944000
CY2015 us-gaap Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
143015000
CY2014 mcrb Proceeds From Issuance Of Common And Restricted Stocks
ProceedsFromIssuanceOfCommonAndRestrictedStocks
5000
CY2015 us-gaap Repayments Of Notes Payable
RepaymentsOfNotesPayable
2600000
CY2014 us-gaap Repayments Of Notes Payable
RepaymentsOfNotesPayable
400000
CY2015 us-gaap Payments For Repurchase Of Initial Public Offering
PaymentsForRepurchaseOfInitialPublicOffering
2928000
CY2014 us-gaap Payments For Repurchase Of Initial Public Offering
PaymentsForRepurchaseOfInitialPublicOffering
821000
CY2015 us-gaap Net Cash Provided By Used In Financing Activities Continuing Operations
NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
137725000
CY2014 us-gaap Net Cash Provided By Used In Financing Activities Continuing Operations
NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
123992000
CY2013 us-gaap Net Cash Provided By Used In Financing Activities Continuing Operations
NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
944000
CY2015 us-gaap Cash And Cash Equivalents Period Increase Decrease
CashAndCashEquivalentsPeriodIncreaseDecrease
-40252000
CY2014 us-gaap Cash And Cash Equivalents Period Increase Decrease
CashAndCashEquivalentsPeriodIncreaseDecrease
112531000
CY2013 us-gaap Cash And Cash Equivalents Period Increase Decrease
CashAndCashEquivalentsPeriodIncreaseDecrease
-4561000
CY2013Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
1654000
CY2012Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
6215000
CY2015 us-gaap Interest Paid
InterestPaid
163000
CY2014 us-gaap Interest Paid
InterestPaid
122000
CY2013 us-gaap Interest Paid
InterestPaid
20000
CY2013 mcrb Issuance Of Warrants In Connection With Notes Payable
IssuanceOfWarrantsInConnectionWithNotesPayable
156000
CY2014 us-gaap Liabilities Assumed1
LiabilitiesAssumed1
863000
CY2015 us-gaap Capital Expenditures Incurred But Not Yet Paid
CapitalExpendituresIncurredButNotYetPaid
2953000
CY2014 us-gaap Capital Expenditures Incurred But Not Yet Paid
CapitalExpendituresIncurredButNotYetPaid
101000
CY2015 us-gaap Use Of Estimates
UseOfEstimates
<div> <p style="margin-top:6pt;margin-bottom:0pt;text-indent:0%;font-weight:bold;font-family:Times New Roman;font-size:10pt;font-style:normal;text-transform:none;font-variant: normal;">Use of Estimates</p> <p style="margin-top:6pt;margin-bottom:0pt;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;text-indent:4.54%;">The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, the disclosure of contingent assets and liabilities at the date of the consolidated financial statements and the reported amounts of expenses during the reporting periods. Significant estimates and assumptions reflected in these consolidated financial statements include, but are not limited to, the accrual of research and development expenses and the valuation of common stock, stock-based awards and the preferred stock warrant liability. Estimates are periodically reviewed in light of changes in circumstances, facts and experience. Actual results could differ from the Company&#8217;s estimates.</p></div>
CY2015 us-gaap Concentration Risk Credit Risk
ConcentrationRiskCreditRisk
<div> <p style="margin-top:18pt;margin-bottom:0pt;text-indent:0%;font-weight:bold;font-family:Times New Roman;font-size:10pt;font-style:normal;text-transform:none;font-variant: normal;">Concentration of Credit Risk and of Significant Suppliers</p> <p style="margin-top:6pt;margin-bottom:0pt;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;text-indent:4.54%;">Financial instruments that potentially expose the Company to concentrations of credit risk consist primarily of cash, cash equivalents and investments. The Company has all cash, cash equivalents and investments balances at one accredited financial institution, in amounts that exceed federally insured limits. The Company does not believe that it is subject to unusual credit risk beyond the normal credit risk associated with commercial banking relationships.</p> <p style="margin-top:12pt;margin-bottom:0pt;text-indent:4.54%;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">The Company is dependent on third-party manufacturers to supply products for research and development activities of its programs, including pre-clinical and clinical testing. These programs could be adversely affected by a significant interruption in the supply of such drug substance products.</p></div>
CY2015Q4 us-gaap Fair Value Assets Level2 To Level1 Transfers Amount
FairValueAssetsLevel2ToLevel1TransfersAmount
0
CY2014Q4 us-gaap Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
1547000
CY2015Q4 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
1011000
CY2015Q4 us-gaap Fair Value Assets Level1 To Level2 Transfers Amount
FairValueAssetsLevel1ToLevel2TransfersAmount
0
CY2014Q4 us-gaap Fair Value Assets Level1 To Level2 Transfers Amount
FairValueAssetsLevel1ToLevel2TransfersAmount
0
CY2015Q4 us-gaap Cash Cash Equivalents And Short Term Investments
CashCashEquivalentsAndShortTermInvestments
205082000
CY2015 mcrb Cash Equivalents Original Maturity Maximum Period
CashEquivalentsOriginalMaturityMaximumPeriod
P90D
CY2015Q3 mcrb Reclassification Of Deferred Offering Costs To Additional Paid In Capital
ReclassificationOfDeferredOfferingCostsToAdditionalPaidInCapital
3748000
CY2015 us-gaap Impairment Of Long Lived Assets Held For Use
ImpairmentOfLongLivedAssetsHeldForUse
0
CY2015 mcrb Minimum Percentage Of Likelihood Of Tax Benefit Being Realized Upon Settlement
MinimumPercentageOfLikelihoodOfTaxBenefitBeingRealizedUponSettlement
0.50
CY2015 us-gaap Revenues
Revenues
0
CY2014Q4 us-gaap Fair Value Assets Level2 To Level1 Transfers Amount
FairValueAssetsLevel2ToLevel1TransfersAmount
0
CY2015 us-gaap Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers Net
FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetTransfersNet
0
CY2014 us-gaap Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers Net
FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetTransfersNet
0
CY2015Q4 us-gaap Available For Sale Securities Amortized Cost
AvailableForSaleSecuritiesAmortizedCost
131116000
CY2015Q4 us-gaap Available For Sale Securities Accumulated Gross Unrealized Gain Before Tax
AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
87000
CY2015Q4 us-gaap Available For Sale Securities Accumulated Gross Unrealized Loss Before Tax
AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
54000
CY2015Q4 us-gaap Available For Sale Securities
AvailableForSaleSecurities
131149000
CY2015Q4 us-gaap Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
8762000
CY2014Q4 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
283000
CY2015Q4 mcrb Accrued Development And Clinical Manufacturing Costs Current
AccruedDevelopmentAndClinicalManufacturingCostsCurrent
1436000
CY2014Q4 mcrb Accrued Development And Clinical Manufacturing Costs Current
AccruedDevelopmentAndClinicalManufacturingCostsCurrent
598000
CY2015Q4 us-gaap Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
2756000
CY2014Q4 us-gaap Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
547000
CY2015Q4 us-gaap Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
184000
CY2014Q4 us-gaap Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
314000
CY2015Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
1147000
CY2014Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
278000
CY2015 us-gaap Fair Value Assumptions Risk Free Interest Rate
FairValueAssumptionsRiskFreeInterestRate
0.0240
CY2014 us-gaap Fair Value Assumptions Risk Free Interest Rate
FairValueAssumptionsRiskFreeInterestRate
0.0217
CY2013 us-gaap Fair Value Assumptions Risk Free Interest Rate
FairValueAssumptionsRiskFreeInterestRate
0.0320
CY2015 us-gaap Fair Value Assumptions Expected Term
FairValueAssumptionsExpectedTerm
P8Y2M12D
CY2014 us-gaap Fair Value Assumptions Expected Term
FairValueAssumptionsExpectedTerm
P8Y8M12D
CY2013 us-gaap Fair Value Assumptions Expected Term
FairValueAssumptionsExpectedTerm
P9Y8M12D
CY2015 us-gaap Fair Value Assumptions Expected Volatility Rate
FairValueAssumptionsExpectedVolatilityRate
0.912
CY2014 us-gaap Fair Value Assumptions Expected Volatility Rate
FairValueAssumptionsExpectedVolatilityRate
0.840
CY2013 us-gaap Fair Value Assumptions Expected Volatility Rate
FairValueAssumptionsExpectedVolatilityRate
0.860
CY2015 us-gaap Fair Value Assumptions Expected Dividend Rate
FairValueAssumptionsExpectedDividendRate
0.00
CY2014 us-gaap Fair Value Assumptions Expected Dividend Rate
FairValueAssumptionsExpectedDividendRate
0.00
CY2013 us-gaap Fair Value Assumptions Expected Dividend Rate
FairValueAssumptionsExpectedDividendRate
0.00
CY2012Q4 us-gaap Warrants Not Settleable In Cash Fair Value Disclosure
WarrantsNotSettleableInCashFairValueDisclosure
0
CY2013Q4 us-gaap Warrants Not Settleable In Cash Fair Value Disclosure
WarrantsNotSettleableInCashFairValueDisclosure
164000
CY2014Q4 us-gaap Warrants Not Settleable In Cash Fair Value Disclosure
WarrantsNotSettleableInCashFairValueDisclosure
1582000
CY2015 mcrb Reclassification Of Warrant Liabilities To Equity
ReclassificationOfWarrantLiabilitiesToEquity
1589000
CY2015Q4 us-gaap Warrants Not Settleable In Cash Fair Value Disclosure
WarrantsNotSettleableInCashFairValueDisclosure
0
CY2014Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
3579342
CY2015 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
1750124
CY2015 us-gaap Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
232970
CY2015 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod
70250
CY2015Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
5026246
CY2015Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber
5026246
CY2015Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber
1643955
CY2014Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
1.38
CY2015 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
20.44
CY2015 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
0.40
CY2015 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice
5.04
CY2015Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
8.01
CY2015Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice
8.01
CY2015Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice
1.33
CY2014 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
P9Y2M16D
CY2015 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
P8Y8M12D
CY2015 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1
P8Y8M12D
CY2015 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1
P8Y1M17D
CY2014Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
59498000
CY2014 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
4.25
CY2015Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
136945000
CY2013 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
0.35
CY2015Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Reserves And Accruals Accrued Liabilities
DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities
977000
CY2015Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Aggregate Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue
136945000
CY2015Q4 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1
55507000
CY2013 us-gaap Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
2695000
CY2015Q1 us-gaap Operating Expenses
OperatingExpenses
8167000
CY2015Q2 us-gaap Operating Expenses
OperatingExpenses
12340000
CY2014Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Reserves And Accruals Accrued Liabilities
DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities
447000
CY2015Q4 mcrb Deferred Tax Assets Deferred Expense Capitalized Research And Development Costs
DeferredTaxAssetsDeferredExpenseCapitalizedResearchAndDevelopmentCosts
126000
CY2014Q4 mcrb Deferred Tax Assets Deferred Expense Capitalized Research And Development Costs
DeferredTaxAssetsDeferredExpenseCapitalizedResearchAndDevelopmentCosts
136000
CY2015Q4 us-gaap Deferred Tax Assets Gross
DeferredTaxAssetsGross
33005000
CY2015 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
14.56
CY2015 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
4125000
CY2015Q4 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Number Of Shares
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares
27750
CY2014Q4 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Number Of Shares
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares
69688
CY2015 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
9694000
CY2014 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
2068000
CY2013 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
209000
CY2015Q4 us-gaap Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Share Based Awards Other Than Options
EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions
32665000
CY2015 us-gaap Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1
EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1
P3Y1M6D
CY2015 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
5026246
CY2014 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
25940702
CY2013 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
12030902
CY2015 us-gaap Lease Expiration Date1
LeaseExpirationDate1
2018-01-31
CY2015Q4 us-gaap Operating Leases Future Minimum Payments Due Current
OperatingLeasesFutureMinimumPaymentsDueCurrent
1274000
CY2015Q4 us-gaap Operating Leases Future Minimum Payments Due In Two Years
OperatingLeasesFutureMinimumPaymentsDueInTwoYears
1162000
CY2015Q4 us-gaap Operating Leases Future Minimum Payments Due In Three Years
OperatingLeasesFutureMinimumPaymentsDueInThreeYears
643000
CY2015Q4 us-gaap Operating Leases Future Minimum Payments Due In Four Years
OperatingLeasesFutureMinimumPaymentsDueInFourYears
478000
CY2015Q4 us-gaap Operating Leases Future Minimum Payments Due In Five Years
OperatingLeasesFutureMinimumPaymentsDueInFiveYears
80000
CY2015Q4 us-gaap Operating Leases Future Minimum Payments Due
OperatingLeasesFutureMinimumPaymentsDue
3637000
CY2014 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
0
CY2013 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
0
CY2014 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
-0.340
CY2013 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
-0.340
CY2014 us-gaap Effective Income Tax Rate Reconciliation Tax Credits Research
EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
0.038
CY2013 us-gaap Effective Income Tax Rate Reconciliation Tax Credits Research
EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
0.061
CY2014 us-gaap Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
-0.053
CY2013 us-gaap Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
-0.053
CY2014 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
0.023
CY2013 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
0.012
CY2014 mcrb Effective Income Tax Rate Reconciliation Revaluation Of Preferred Stock Warrant Liability
EffectiveIncomeTaxRateReconciliationRevaluationOfPreferredStockWarrantLiability
0.033
CY2014 us-gaap Effective Income Tax Rate Reconciliation Other Reconciling Items Percent
EffectiveIncomeTaxRateReconciliationOtherReconcilingItemsPercent
0.002
CY2013 us-gaap Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
0.442
CY2013 us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
0.00
CY2015Q4 us-gaap Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
25293000
CY2014Q4 us-gaap Deferred Tax Assets Gross
DeferredTaxAssetsGross
10591000
CY2015Q4 us-gaap Deferred Tax Liabilities Property Plant And Equipment
DeferredTaxLiabilitiesPropertyPlantAndEquipment
228000
CY2014Q4 us-gaap Deferred Tax Liabilities Property Plant And Equipment
DeferredTaxLiabilitiesPropertyPlantAndEquipment
69000
CY2015Q4 us-gaap Deferred Income Tax Liabilities
DeferredIncomeTaxLiabilities
228000
CY2014Q4 us-gaap Deferred Income Tax Liabilities
DeferredIncomeTaxLiabilities
69000
CY2015Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
32777000
CY2014Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
10522000
CY2015Q4 us-gaap Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
0
CY2014Q4 us-gaap Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
0
CY2013Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
4294000
CY2012Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
1599000
CY2015 us-gaap Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
22255000
CY2014 us-gaap Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
6228000
CY2015Q3 us-gaap Operating Expenses
OperatingExpenses
14561000
CY2015Q4 us-gaap Operating Expenses
OperatingExpenses
19788000
CY2015Q1 us-gaap Operating Income Loss
OperatingIncomeLoss
-8167000
CY2015Q2 us-gaap Operating Income Loss
OperatingIncomeLoss
-12340000
CY2015Q3 us-gaap Operating Income Loss
OperatingIncomeLoss
-14561000
CY2015Q4 us-gaap Operating Income Loss
OperatingIncomeLoss
-19788000
CY2015Q1 us-gaap Net Income Loss
NetIncomeLoss
-7971000
CY2015Q2 us-gaap Net Income Loss
NetIncomeLoss
-12555000
CY2015Q3 us-gaap Net Income Loss
NetIncomeLoss
-14620000
CY2015Q4 us-gaap Net Income Loss
NetIncomeLoss
-19634000
CY2015Q1 us-gaap Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
-1.15
CY2015Q2 us-gaap Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
-1.45
CY2015Q3 us-gaap Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
-0.38
CY2015Q4 us-gaap Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
-0.50
CY2014Q1 us-gaap Operating Expenses
OperatingExpenses
1672000
CY2014Q2 us-gaap Operating Expenses
OperatingExpenses
2618000
CY2014Q3 us-gaap Operating Expenses
OperatingExpenses
3579000
CY2014Q1 us-gaap Operating Income Loss
OperatingIncomeLoss
-1672000
CY2014Q2 us-gaap Operating Income Loss
OperatingIncomeLoss
-2618000
CY2014Q3 us-gaap Operating Income Loss
OperatingIncomeLoss
-3579000
CY2014Q1 us-gaap Net Income Loss
NetIncomeLoss
-1689000
CY2014Q2 us-gaap Net Income Loss
NetIncomeLoss
-2677000
CY2014Q3 us-gaap Net Income Loss
NetIncomeLoss
-4161000
CY2014Q1 us-gaap Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
-0.29
CY2014Q2 us-gaap Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
-0.45
CY2014Q3 us-gaap Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
-0.68

Files In Submission

Name View Source Status
0001564590-16-014692-index-headers.html Edgar Link pending
0001564590-16-014692-index.html Edgar Link pending
0001564590-16-014692.txt Edgar Link pending
0001564590-16-014692-xbrl.zip Edgar Link pending
FilingSummary.xml Edgar Link unprocessable
Financial_Report.xlsx Edgar Link pending
g2016031418140029012535.jpg Edgar Link pending
g2016031418140130612536.jpg Edgar Link pending
g2016031418140155612537.jpg Edgar Link pending
g2016031418140165012538.jpg Edgar Link pending
g2016031418140210312539.jpg Edgar Link pending
g2016031418141748412540.jpg Edgar Link pending
g2016031418155455112541.jpg Edgar Link pending
g2016031418155458212542.jpg Edgar Link pending
g2016031418155462912543.jpg Edgar Link pending
g2016031418155466012544.jpg Edgar Link pending
g2016031418155469112545.jpg Edgar Link pending
g2016031418155472212546.jpg Edgar Link pending
g2016031418155476912547.jpg Edgar Link pending
g2016031418155480112548.jpg Edgar Link pending
g2016031418155484712549.jpg Edgar Link pending
g2016031418155487912550.jpg Edgar Link pending
g2016031418155491012551.jpg Edgar Link pending
g2016031418155494112552.jpg Edgar Link pending
g2016031418155520712553.jpg Edgar Link pending
g2016031418155522212554.jpg Edgar Link pending
g2016031418155541012555.jpg Edgar Link pending
g2016031418155717812556.jpg Edgar Link pending
g2016031418155722512557.jpg Edgar Link pending
g2016031418155725712558.jpg Edgar Link pending
g2016031418155728812559.jpg Edgar Link pending
g2016031418155731912560.jpg Edgar Link pending
g2016031418155736612561.jpg Edgar Link pending
g2016031418155739712562.jpg Edgar Link pending
g2016031418155742812563.jpg Edgar Link pending
g2016031418155747512564.jpg Edgar Link pending
g2016031418155752212565.jpg Edgar Link pending
g2016031418155755312566.jpg Edgar Link pending
g2016031418155760012567.jpg Edgar Link pending
g2016031418155763212568.jpg Edgar Link pending
g2016031418155766312569.jpg Edgar Link pending
g2016031418155769412570.jpg Edgar Link pending
g2016031418155774112571.jpg Edgar Link pending
g2016031418155778812572.jpg Edgar Link pending
g2016031418155783512573.jpg Edgar Link pending
g2016031418155788212574.jpg Edgar Link pending
g2016031418155791312575.jpg Edgar Link pending
g2016031418155794412576.jpg Edgar Link pending
g2016031418155797512577.jpg Edgar Link pending
g2016031418155806912578.jpg Edgar Link pending
g2016031418160227612579.jpg Edgar Link pending
g2016031418160333812580.jpg Edgar Link pending
g2016031418160340012580.jpg Edgar Link pending
g2016031418160346312580.jpg Edgar Link pending
g2016031418160350912581.jpg Edgar Link pending
g2016031418160354112582.jpg Edgar Link pending
g2016031418160357212583.jpg Edgar Link pending
g2016031418160361912584.jpg Edgar Link pending
g2016031418160366612585.jpg Edgar Link pending
g2016031418160369712586.jpg Edgar Link pending
g2016031418160374412587.jpg Edgar Link pending
g2016031418160379112588.jpg Edgar Link pending
g2016031418160382212589.jpg Edgar Link pending
g2016031418160386912590.jpg Edgar Link pending
g2016031418160393112591.jpg Edgar Link pending
g2016031418160396312592.jpg Edgar Link pending
g2016031418160400912593.jpg Edgar Link pending
g2016031418160404112594.jpg Edgar Link pending
g2016031418160407212595.jpg Edgar Link pending
g2016031418160411912596.jpg Edgar Link pending
g2016031418160415012597.jpg Edgar Link pending
g2016031418160419712598.jpg Edgar Link pending
g2016031418160422812599.jpg Edgar Link pending
g2016031418160425912600.jpg Edgar Link pending
g2016031418160430612601.jpg Edgar Link pending
g2016031418160433812602.jpg Edgar Link pending
g2016031418160436912603.jpg Edgar Link pending
g2016031418160441612604.jpg Edgar Link pending
g2016031418160444712605.jpg Edgar Link pending
g2016031418160449412606.jpg Edgar Link pending
g2016031418160452512607.jpg Edgar Link pending
g2016031418160458812608.jpg Edgar Link pending
g2016031418160463412609.jpg Edgar Link pending
g2016031418160466612610.jpg Edgar Link pending
g2016031418160471312611.jpg Edgar Link pending
g2016031418160474412612.jpg Edgar Link pending
g2016031418160569712613.jpg Edgar Link pending
g2016031418160675912614.jpg Edgar Link pending
g2016031418160691612615.jpg Edgar Link pending
g2016031418160972812616.jpg Edgar Link pending
g2016031418160979112617.jpg Edgar Link pending
g2016031418161136912618.jpg Edgar Link pending
g2016031418161246312619.jpg Edgar Link pending
g2016031418161522912620.jpg Edgar Link pending
g2016031418161527512621.jpg Edgar Link pending
g2016031418161533812622.jpg Edgar Link pending
g2016031418161540012623.jpg Edgar Link pending
g2016031418161546312624.jpg Edgar Link pending
g2016031418161555712625.jpg Edgar Link pending
g2016031418161561912626.jpg Edgar Link pending
g2016031418161566612627.jpg Edgar Link pending
g2016031418161572912628.jpg Edgar Link pending
g2016031418161622912629.jpg Edgar Link pending
g2016031418161635412630.jpg Edgar Link pending
g2016031418162009112630.jpg Edgar Link pending
g2016031418162020012631.jpg Edgar Link pending
g2016031418162174712632.jpg Edgar Link pending
mcrb-10k_20151231.htm Edgar Link pending
mcrb-20151231.xml Edgar Link completed
mcrb-20151231.xsd Edgar Link pending
mcrb-20151231_cal.xml Edgar Link unprocessable
mcrb-20151231_def.xml Edgar Link unprocessable
mcrb-20151231_lab.xml Edgar Link unprocessable
mcrb-20151231_pre.xml Edgar Link unprocessable
mcrb-ex1013_656.htm Edgar Link pending
mcrb-ex231_1760.htm Edgar Link pending
mcrb-ex311_7.htm Edgar Link pending
mcrb-ex312_9.htm Edgar Link pending
mcrb-ex321_8.htm Edgar Link pending
mcrb-ex322_171.htm Edgar Link pending
R1.htm Edgar Link pending
R10.htm Edgar Link pending
R11.htm Edgar Link pending
R12.htm Edgar Link pending
R13.htm Edgar Link pending
R14.htm Edgar Link pending
R15.htm Edgar Link pending
R16.htm Edgar Link pending
R17.htm Edgar Link pending
R18.htm Edgar Link pending
R19.htm Edgar Link pending
R2.htm Edgar Link pending
R20.htm Edgar Link pending
R21.htm Edgar Link pending
R22.htm Edgar Link pending
R23.htm Edgar Link pending
R24.htm Edgar Link pending
R25.htm Edgar Link pending
R26.htm Edgar Link pending
R27.htm Edgar Link pending
R28.htm Edgar Link pending
R29.htm Edgar Link pending
R3.htm Edgar Link pending
R30.htm Edgar Link pending
R31.htm Edgar Link pending
R32.htm Edgar Link pending
R33.htm Edgar Link pending
R34.htm Edgar Link pending
R35.htm Edgar Link pending
R36.htm Edgar Link pending
R37.htm Edgar Link pending
R38.htm Edgar Link pending
R39.htm Edgar Link pending
R4.htm Edgar Link pending
R40.htm Edgar Link pending
R41.htm Edgar Link pending
R42.htm Edgar Link pending
R43.htm Edgar Link pending
R44.htm Edgar Link pending
R45.htm Edgar Link pending
R46.htm Edgar Link pending
R47.htm Edgar Link pending
R48.htm Edgar Link pending
R49.htm Edgar Link pending
R5.htm Edgar Link pending
R50.htm Edgar Link pending
R51.htm Edgar Link pending
R52.htm Edgar Link pending
R53.htm Edgar Link pending
R54.htm Edgar Link pending
R55.htm Edgar Link pending
R56.htm Edgar Link pending
R57.htm Edgar Link pending
R58.htm Edgar Link pending
R59.htm Edgar Link pending
R6.htm Edgar Link pending
R60.htm Edgar Link pending
R61.htm Edgar Link pending
R62.htm Edgar Link pending
R63.htm Edgar Link pending
R64.htm Edgar Link pending
R65.htm Edgar Link pending
R66.htm Edgar Link pending
R67.htm Edgar Link pending
R68.htm Edgar Link pending
R69.htm Edgar Link pending
R7.htm Edgar Link pending
R70.htm Edgar Link pending
R71.htm Edgar Link pending
R72.htm Edgar Link pending
R73.htm Edgar Link pending
R8.htm Edgar Link pending
R9.htm Edgar Link pending
report.css Edgar Link pending
Show.js Edgar Link pending