| Insider Name | Current Shares | Net Change (1yr) | Buy/Sell Ratio |
|---|---|---|---|
| AG NOVARTIS | 5,652,903 | 0 | - |
| Institutes for BioMedical Research, Inc. Novartis | 4,129,903 | 0 | - |
| Biosciences, Inc. Caribou | 3,994,355 | 0 | - |
| Venture Associates IX, LLC Atlas | 3,579,788 | 0 | - |
| SAMUEL D ISALY | 2,603,646 | 0 | - |
| JOHN M LEONARD | 1,169,739 | +130,811 | 2.56 |
| Beta Pte. Ltd. TLS | 790,527 | 0 | - |
| JOHN M. LEONARD | 467,352 | 0 | - |
| Rachel E. Haurwitz | 349,612 | 0 | - |
| Nessan Bermingham | 292,500 | 0 | - |
| Fred E Cohen | 207,453 | +158,000 | ∞ |
| Edward J III Dulac | 160,963 | +47,439 | 4.43 |
| JAMES BASTA | 156,794 | +34,472 | 3.97 |
| Jose E Rivera | 146,832 | 0 | - |
| Birgit C Schultes | 137,733 | +30,661 | 4.59 |
| WILLIAM J CHASE | 134,693 | +108,000 | ∞ |
| David Lebwohl | 131,192 | -1,960 | 0.84 |
| Eliana Clark | 93,864 | -3,791 | 0.66 |
| Bros. Advisors (GP) LLC Baker | 85,906 | 0 | - |
| ANDREW SCHIERMEIER | 78,750 | 0 | - |
| Laura Sepp-Lorenzino | 77,388 | 0 | - |
| Michael P Dube | 69,527 | +9,887 | 2.34 |
| Glenn Goddard | 69,213 | 0 | - |
| Derek Hicks | 59,878 | 0 | - |
| Thomas M. Barnes | 50,500 | 0 | - |
| Moncef Slaoui | 38,000 | 0 | - |
| PERRY A KARSEN | 36,764 | 0 | - |
| Georgia Keresty | 31,883 | +8,000 | ∞ |
| David V Morrissey | 30,000 | 0 | - |
| Nicole Heifner | 28,500 | 0 | - |
| Muna Bhanji | 27,203 | +8,000 | ∞ |
| Frank Verwiel | 25,948 | +8,000 | ∞ |
| JESSE GOODMAN | 24,359 | +4,906 | 2.59 |
| Brian Goff | 23,409 | +8,000 | ∞ |
| Graeme Bell | 21,400 | 0 | - |
| CARL L GORDON | 19,000 | 0 | - |
| CAROLINE DORSA | 12,701 | 0 | - |
| John F Crowley | 11,716 | 0 | - |
| JEAN FRANCOIS FORMELA | 7,291 | 0 | - |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| JAMES BASTA | Mar 03 |
Open Market Sale (S)
Market Sale
|
156,794 | -1,211 | $13.78 | -$16,687 |
| Eliana Clark | Mar 03 |
Open Market Sale (S)
Market Sale
|
93,864 | -607 | $13.78 | -$8,364 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Michael P Dube | Mar 03 |
Grant/Award Acquisition (A)
Compensation/Award
|
69,527 | +17,250 | $0.00 | +$0 |
| Birgit C Schultes | Mar 03 |
Grant/Award Acquisition (A)
Compensation/Award
|
137,733 | +39,200 | $0.00 | +$0 |
| Edward J III Dulac | Mar 03 |
Grant/Award Acquisition (A)
Compensation/Award
|
160,963 | +61,280 | $0.00 | +$0 |
| David Lebwohl | Mar 03 |
Grant/Award Acquisition (A)
Compensation/Award
|
131,192 | +9,943 | $0.00 | +$0 |
| JOHN M LEONARD | Mar 03 |
Grant/Award Acquisition (A)
Compensation/Award
|
1,169,739 | +156,400 | $0.00 | +$0 |
| Eliana Clark | Mar 03 |
Grant/Award Acquisition (A)
Compensation/Award
|
94,471 | +7,353 | $0.00 | +$0 |
| JAMES BASTA | Mar 03 |
Grant/Award Acquisition (A)
Compensation/Award
|
158,005 | +46,080 | $0.00 | +$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Birgit C Schultes | Jan 07 |
Open Market Sale (S)
Market Sale
|
98,533 | -8,508 | $9.21 | -$78,358 |
| JAMES BASTA | Jan 07 |
Open Market Sale (S)
Market Sale
|
101,528 | -10,397 | $9.21 | -$95,756 |
| David Lebwohl | Jan 07 |
Open Market Sale (S)
Market Sale
|
121,249 | -11,903 | $9.21 | -$109,626 |
| Eliana Clark | Jan 07 |
Open Market Sale (S)
Market Sale
|
87,118 | -9,515 | $9.21 | -$87,633 |
| Edward J III Dulac | Jan 07 |
Open Market Sale (S)
Market Sale
|
99,683 | -6,379 | $9.21 | -$58,750 |
| Michael P Dube | Jan 07 |
Open Market Sale (S)
Market Sale
|
52,277 | -2,989 | $9.21 | -$27,528 |
| JOHN M LEONARD | Jan 07 |
Open Market Sale (S)
Market Sale
|
1,013,339 | -34,146 | $9.21 | -$314,484 |
| Fred E Cohen | Jan 07 |
Open Market Purchase (P)
Market Purchase
|
207,453 | +150,000 | $9.35 | +$1,402,500 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| JOHN M LEONARD | Dec 12 |
Option Exercise/Conversion (M)
Compensation/Award
|
1,047,485 | +8,557 | $6.83 | +$58,444 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| JOHN M LEONARD | Dec 12 |
Open Market Sale (S)
Market Sale
|
1,077,115 | -49,959 | $9.49 | -$474,110 |
| JOHN M LEONARD | Dec 12 |
Option Exercise/Conversion (M)
Compensation/Award
|
1,127,074 | +49,959 | $6.83 | +$341,219 |
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