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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation and amortization | |||||
| Stock-based compensation | |||||
| Issuance of PIK interest debt | |||||
| Accrued interest on revenue interest financing liability | |||||
| Accrued payment-in-kind interest on debt | |||||
| Accrued interest on revenue interest financing liability, net of payments | |||||
| Amortization of debt discount | |||||
| Inventory reserve | |||||
| Other | |||||
| Changes in operating assets and liabilities: | |||||
| Prepaid expenses and other current assets | |||||
| Accounts receivable, net | |||||
| Accounts payable and accrued expenses | |||||
| Accrued clinical trial expenses | |||||
| Accrued interest | |||||
| Operating right-of-use assets and lease liabilities | |||||
| Inventory | |||||
| Other long-term assets | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities | |||||
| Cash paid for property and equipment | |||||
| Net cash used in investing activities | |||||
| Cash flows from financing activities | |||||
| Proceeds from issuance of common stock from exercise of stock options | |||||
| Net proceeds from issuance of debt | |||||
| Net proceeds from underwritten public offering | |||||
| Payment of employee tax obligations related to vesting of PSUs and RSUs | |||||
| Net proceeds from revenue interest financing transaction | |||||
| Net proceeds from issuance of common stock | |||||
| At-the-Market Offering Program | |||||
| Total net proceeds from issuance of common stock | |||||
| Net cash (used in) provided by financing activities | |||||
| Net decrease in cash and cash equivalents and restricted cash | |||||
| Cash and cash equivalents and restricted cash - beginning of period | |||||
| Cash and cash equivalents and restricted cash - end of period | |||||
| Supplemental disclosure of cash flow information | |||||
| Interest paid | |||||
| Supplemental disclosure of noncash investing and financing activities | |||||
| Property and equipment purchases included in accounts payable and accrued expenses | |||||
| Final interest payment fee | |||||
| Settlement of ESPP liability in common stock | |||||
| Settlement of 401(k) liability in common stock | |||||
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