$PRTA
PROTHENA CORP PUBLIC LTD CO Stock $prta

$prta Overview Financials Valuation SEC Filings Company Website

2019 Q2 Form 10-Q Financial Statement

#000155905319000013 Filed on May 07, 2019

Income Statement

Concept	2019 Q2	2019 Q1	2018 Q1
Revenue	$167.0K	$186.0K	$227.0K
YoY Change	-40.14%	-18.06%	-12.36%
Cost Of Revenue
YoY Change
Gross Profit
YoY Change
Gross Profit Margin
Selling, General & Admin	$9.080M	$9.910M	$14.23M
YoY Change	-17.38%	-30.36%	31.39%
% of Gross Profit
Research & Development	$9.583M	$13.30M	$34.71M
YoY Change	-69.53%	-61.69%	35.05%
% of Gross Profit
Depreciation & Amortization	$400.0K	$385.0K	$797.0K
YoY Change	-50.0%	-51.69%	5.01%
% of Gross Profit
Operating Expenses	$18.66M	$23.14M	$48.94M
YoY Change	-70.54%	-52.71%	33.96%
Operating Profit	-$18.50M	-$22.95M	-$48.71M
YoY Change	-70.67%	-52.87%	34.29%
Interest Expense	$2.300M	$2.300M	$200.0K
YoY Change	177.11%	1050.0%	-155.56%
% of Operating Profit
Other Income/Expense, Net	$2.531M	$2.287M	-$72.00K
YoY Change	103.95%	-3276.39%	-90.7%
Pretax Income	-$15.97M	-$20.67M	-$48.78M
YoY Change	-74.18%	-57.63%	31.68%
Income Tax	-$156.0K	$198.0K	-$37.00K
% Of Pretax Income
Net Earnings	-$15.81M	-$20.87M	-$48.74M
YoY Change	-73.6%	-57.19%	37.75%
Net Earnings / Revenue	-9467.07%	-11217.74%	-21472.69%
Basic Earnings Per Share	-$0.40	-$0.52	-$1.26
Diluted Earnings Per Share	-$0.40	-$0.52	-$1.26
COMMON SHARES
Basic Shares Outstanding	39.86M shares	39.86M shares	38.54M shares
Diluted Shares Outstanding

Balance Sheet

Concept	2019 Q2	2019 Q1	2018 Q1
SHORT-TERM ASSETS
Cash & Short-Term Investments	$398.1M	$410.1M	$429.0M
YoY Change	-18.12%	-4.41%	-15.32%
Cash & Equivalents	$398.1M	$410.1M	$429.0M
Short-Term Investments
Other Short-Term Assets	$3.462M	$5.100M	$8.100M
YoY Change	-55.62%	-37.04%	9.46%
Inventory
Prepaid Expenses
Receivables			$12.00K
Other Receivables			$0.00
Total Short-Term Assets	$418.7M	$415.2M	$537.2M
YoY Change	-15.25%	-22.7%	4.46%
LONG-TERM ASSETS
Property, Plant & Equipment	$4.318M	$4.976M	$54.28M
YoY Change	-91.91%	-90.83%	-3.22%
Goodwill
YoY Change
Intangibles
YoY Change
Long-Term Investments
YoY Change
Other Assets	$923.0K	$868.0K	$2.840M
YoY Change	83.86%	-69.44%	16.87%
Total Long-Term Assets	$43.36M	$44.34M	$69.49M
YoY Change	-37.39%	-36.19%	2.58%
TOTAL ASSETS
Total Short-Term Assets	$418.7M	$415.2M	$537.2M
Total Long-Term Assets	$43.36M	$44.34M	$69.49M
Total Assets	$462.1M	$459.5M	$606.6M
YoY Change	-17.97%	-24.25%	4.24%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable	$1.525M	$2.103M	$11.59M
YoY Change	-84.83%	-81.86%	85.32%
Accrued Expenses	$10.00M	$11.70M	$20.20M
YoY Change	-29.08%	-42.08%	-20.78%
Deferred Revenue
YoY Change
Short-Term Debt	$0.00	$0.00	$0.00
YoY Change
Long-Term Debt Due	$0.00	$0.00	$1.100M
YoY Change	-100.0%	-100.0%
Total Short-Term Liabilities	$28.02M	$14.91M	$35.56M
YoY Change	-39.27%	-58.08%	5.57%
LONG-TERM LIABILITIES
Long-Term Debt	$0.00	$0.00	$51.10M
YoY Change	-100.0%	-100.0%
Other Long-Term Liabilities	$553.0K	$553.0K	$110.5M
YoY Change	-99.5%	-99.5%	112.5%
Total Long-Term Liabilities	$131.2M	$132.5M	$161.6M
YoY Change	-18.56%	-18.0%	210.61%
TOTAL LIABILITIES
Total Short-Term Liabilities	$28.02M	$14.91M	$35.56M
Total Long-Term Liabilities	$131.2M	$132.5M	$161.6M
Total Liabilities	$159.3M	$147.4M	$197.1M
YoY Change	-23.17%	-25.23%	130.03%
SHAREHOLDERS EQUITY
Retained Earnings	-$630.9M	-$594.2M	-$491.1M
YoY Change	14.5%	21.0%	51.34%
Common Stock	$399.0K	$399.0K	$398.0K
YoY Change	0.25%	0.25%	4.74%
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity	$302.8M	$312.1M	$409.5M
YoY Change
Total Liabilities & Shareholders Equity	$462.1M	$459.5M	$606.6M
YoY Change	-17.97%	-24.25%	4.24%

Cashflow Statement

Concept	2019 Q2	2019 Q1	2018 Q1
OPERATING ACTIVITIES
Net Income	-$15.81M	-$20.87M	-$48.74M
YoY Change	-73.6%	-57.19%	37.75%
Depreciation, Depletion And Amortization	$400.0K	$385.0K	$797.0K
YoY Change	-50.0%	-51.69%	5.01%
Cash From Operating Activities	-$12.10M	-$17.44M	-$31.58M
YoY Change	-120.82%	-44.8%	-16.54%
INVESTING ACTIVITIES
Capital Expenditures	-$70.00K	-$130.0K	-$180.0K
YoY Change	-30.0%	-27.78%	-92.8%
Acquisitions
YoY Change
Other Investing Activities	$0.00	$10.00K	$0.00
YoY Change			-100.0%
Cash From Investing Activities	-$70.00K	-$123.0K	-$181.0K
YoY Change	-30.0%	-32.04%	-92.46%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net			$0.00
YoY Change			-100.0%
Debt Paid & Issued, Net
YoY Change
Cash From Financing Activities	210.0K	$5.000K	$43.18M
YoY Change	-124.42%	-99.99%	-72.99%
NET CHANGE
Cash From Operating Activities	-12.10M	-$17.44M	-$31.58M
Cash From Investing Activities	-70.00K	-$123.0K	-$181.0K
Cash From Financing Activities	210.0K	$5.000K	$43.18M
Net Change In Cash	-11.96M	-$17.55M	$11.42M
YoY Change	-120.92%	-253.72%	-90.45%
FREE CASH FLOW
Cash From Operating Activities	-$12.10M	-$17.44M	-$31.58M
Capital Expenditures	-$70.00K	-$130.0K	-$180.0K
Free Cash Flow	-$12.03M	-$17.31M	-$31.40M
YoY Change	-120.66%	-44.9%	-11.14%

Facts In Submission

Frame	Concept Type	Concept / XBRL Key	Value	Unit
CY2019Q1	dei	Amendment Flag AmendmentFlag	false
CY2019Q1	dei	Current Fiscal Year End Date CurrentFiscalYearEndDate	--12-31
CY2019Q1	dei	Document Fiscal Period Focus DocumentFiscalPeriodFocus	Q1
CY2019Q1	dei	Document Fiscal Year Focus DocumentFiscalYearFocus	2019
CY2019Q1	dei	Document Period End Date DocumentPeriodEndDate	2019-03-31
CY2019Q1	dei	Document Type DocumentType	10-Q
CY2019Q1	dei	Entity Central Index Key EntityCentralIndexKey	0001559053
CY2019Q2	dei	Entity Common Stock Shares Outstanding EntityCommonStockSharesOutstanding	39864561	shares
CY2019Q1	dei	Entity Emerging Growth Company EntityEmergingGrowthCompany	false
CY2019Q1	dei	Entity Filer Category EntityFilerCategory	Accelerated Filer
CY2019Q1	dei	Entity Registrant Name EntityRegistrantName	Prothena Corp plc
CY2019Q1	dei	Entity Small Business EntitySmallBusiness	true
CY2019Q1	dei	Trading Symbol TradingSymbol	PRTA
CY2018Q4	prta	Accrued Research And Development Current AccruedResearchAndDevelopmentCurrent	5370000	USD
CY2019Q1	prta	Accrued Research And Development Current AccruedResearchAndDevelopmentCurrent	4738000	USD
CY2018Q1	prta	Amortizationofrightofuseasset Amortizationofrightofuseasset	0	USD
CY2019Q1	prta	Amortizationofrightofuseasset Amortizationofrightofuseasset	1296000	USD
CY2018Q1	prta	Buildto Suit Leases Increase Decreaseto Obligation BuildtoSuitLeasesIncreaseDecreasetoObligation	954000	USD
CY2019Q1	prta	Buildto Suit Leases Increase Decreaseto Obligation BuildtoSuitLeasesIncreaseDecreasetoObligation	0	USD
CY2018Q4	prta	Buildto Suit Property Gross BuildtoSuitPropertyGross	52245000	USD
CY2019Q1	prta	Buildto Suit Property Gross BuildtoSuitPropertyGross	0	USD
CY2018Q4	prta	Buildtosuit Lease Obligation Current BuildtosuitLeaseObligationCurrent	1645000	USD
CY2019Q1	prta	Buildtosuit Lease Obligation Current BuildtosuitLeaseObligationCurrent	0	USD
CY2019Q1	prta	Buildtosuit Lease Obligation Current BuildtosuitLeaseObligationCurrent	0	USD
CY2018Q4	us-gaap	Restricted Cash Current RestrictedCashCurrent	0	USD
CY2018Q4	prta	Buildtosuit Lease Obligation Currentand Noncurrent BuildtosuitLeaseObligationCurrentandNoncurrent	51500000	USD
CY2016Q1	prta	Buildtosuit Lease Termof Contract BuildtosuitLeaseTermofContract	P7Y9M30D
CY2018Q4	prta	Deferred Shares Par Value DeferredSharesParValue	22
CY2019Q1	prta	Deferred Shares Par Value DeferredSharesParValue	22
CY2018Q4	prta	Buildtosuitleaseobligationnoncurrent Buildtosuitleaseobligationnoncurrent	49901000	USD
CY2019Q1	prta	Buildtosuitleaseobligationnoncurrent Buildtosuitleaseobligationnoncurrent	0	USD
CY2019Q1	prta	Buildtosuitleaseobligationnoncurrent Buildtosuitleaseobligationnoncurrent	0	USD
CY2018Q4	prta	Builtto Suit Leases At Cost BuilttoSuitLeasesAtCost	52300000	USD
CY2018Q4	prta	Deferred Shares Share Issued DeferredSharesShareIssued	0	shares
CY2018Q4	prta	Deferred Shares Share Outstanding DeferredSharesShareOutstanding	0	shares
CY2018Q1	prta	Collaboration Revenue CollaborationRevenue	227000	USD
CY2019Q1	prta	Collaboration Revenue CollaborationRevenue	186000	USD
CY2018Q1	prta	Interest Expenseunderbuildtosuittransaction InterestExpenseunderbuildtosuittransaction	908000	USD
CY2019Q1	prta	Interest Expenseunderbuildtosuittransaction InterestExpenseunderbuildtosuittransaction	0	USD
CY2019Q1	prta	Lessee Operating Lease Liability Nominal Payments LesseeOperatingLeaseLiabilityNominalPayments	-17000	USD
CY2019Q1	prta	Numberof Votes NumberofVotes	1	vote
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CY2018Q4	prta	Operating Leases Future Minimum Subsublease Rentals Duein Five Years OperatingLeasesFutureMinimumSubsubleaseRentalsDueinFiveYears	3019000	USD
CY2018Q4	prta	Operating Leases Future Minimum Subsublease Rentals Duein Four Years OperatingLeasesFutureMinimumSubsubleaseRentalsDueinFourYears	3047000	USD
CY2019Q1	prta	Deferred Shares Share Outstanding DeferredSharesShareOutstanding	0.0	shares
CY2019Q1	prta	Deferred Shares Share Outstanding DeferredSharesShareOutstanding	0	shares
CY2018Q4	prta	Deferred Shares Shares Authorized DeferredSharesSharesAuthorized	10000	shares
CY2019Q1	prta	Deferred Shares Shares Authorized DeferredSharesSharesAuthorized	10000	shares
CY2018Q4	prta	Deferred Shares Value DeferredSharesValue	0	USD
CY2019Q1	prta	Deferred Shares Value DeferredSharesValue	0	USD
CY2018Q1	prta	Increase Decreasein Operating Lease Liability IncreaseDecreaseinOperatingLeaseLiability	0	USD
CY2019Q1	prta	Increase Decreasein Operating Lease Liability IncreaseDecreaseinOperatingLeaseLiability	1143000	USD
CY2018Q4	prta	Operating Leases Future Minimum Subsublease Rentals Duein Three Years OperatingLeasesFutureMinimumSubsubleaseRentalsDueinThreeYears	2944000	USD
CY2018Q4	prta	Operating Leases Future Minimum Subsublease Rentals Duein Two Years OperatingLeasesFutureMinimumSubsubleaseRentalsDueinTwoYears	2843000	USD
CY2018Q4	prta	Operating Leases Future Minimum Subsublease Rentals Next Twelve Months OperatingLeasesFutureMinimumSubsubleaseRentalsNextTwelveMonths	2746000	USD
CY2018Q3	prta	Operating Leases Sublease Rentals Areaof Sublease Rental OperatingLeasesSubleaseRentalsAreaofSubleaseRental	46641	sqft
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CY2019Q1	prta	Purchaseand Contractual Obligation Duein Fifth Year PurchaseandContractualObligationDueinFifthYear	80000	USD
CY2019Q1	prta	Purchaseand Contractual Obligation Duein Fourth Year PurchaseandContractualObligationDueinFourthYear	80000	USD
CY2019Q1	prta	Purchaseand Contractual Obligation Duein Second Year PurchaseandContractualObligationDueinSecondYear	95000	USD
CY2019Q1	prta	Purchaseand Contractual Obligation Duein Third Year PurchaseandContractualObligationDueinThirdYear	95000	USD
CY2019Q1	prta	Purchaseand Contractual Obligation Remainderof Fiscal Year PurchaseandContractualObligationRemainderofFiscalYear	1449000	USD
CY2019Q1	prta	Purchaseand Contractual Obligation Total PurchaseandContractualObligationTotal	2334000	USD
CY2018Q1	prta	Receivable Stock Option Exercises ReceivableStockOptionExercises	19000	USD
CY2019Q1	prta	Receivable Stock Option Exercises ReceivableStockOptionExercises	0	USD
CY2018Q1	prta	Reductionof Amounts Capitalized Under Buildtosuit Lease Transaction ReductionofAmountsCapitalizedUnderBuildtosuitLeaseTransaction	0	USD
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CY2018Q1	prta	Reductionof Buildtosuit Lease Obligation ReductionofBuildtosuitLeaseObligation	0	USD
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CY2018Q1	prta	Reductionof Capitalized Interest During Construction Periodfor Buildtosuit Lease Transaction ReductionofCapitalizedInterestDuringConstructionPeriodforBuildtosuitLeaseTransaction	0	USD
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CY2019Q1	prta	Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value Related To Vested Options ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValueRelatedToVestedOptions	3211000	USD
CY2019Q1	prta	Share Based Compensation Arrangement By Share Based Payment Award Options Vested Outstanding Number ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedOutstandingNumber	2635745	shares
CY2019Q1	prta	Share Based Compensation Arrangement By Share Based Payment Award Options Vested Outstanding Weighted Average Remaining Contractual Term ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedOutstandingWeightedAverageRemainingContractualTerm	P5Y7M13D
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CY2018Q1	prta	Sharebased Compensation Net Tax Shortfall Excess Tax Benefit Amount Bookedto Income Tax Provision SharebasedCompensationNetTaxShortfallExcessTaxBenefitAmountBookedtoIncomeTaxProvision	300000	USD
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CY2018Q1	prta	Sharebased Compensationnonrestructuring SharebasedCompensationnonrestructuring	6902000	USD
CY2019Q1	prta	Sharebased Compensationnonrestructuring SharebasedCompensationnonrestructuring	6205000	USD
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CY2019Q1	us-gaap	Accrued Income Taxes Current AccruedIncomeTaxesCurrent	290000	USD
CY2018Q4	us-gaap	Accrued Professional Fees Current AccruedProfessionalFeesCurrent	1097000	USD
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CY2018Q4	us-gaap	Common Stock Value CommonStockValue	399000	USD
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CY2018Q1	us-gaap	Depreciation Depreciation	800000	USD
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CY2019Q1	us-gaap	Income Loss From Continuing Operations Before Income Taxes Minority Interest And Income Loss From Equity Method Investments IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments	-20667000	USD
CY2018Q1	us-gaap	Income Tax Expense Benefit IncomeTaxExpenseBenefit	-37000	USD
CY2019Q1	us-gaap	Income Tax Expense Benefit IncomeTaxExpenseBenefit	198000	USD
CY2018Q1	us-gaap	Income Taxes Paid IncomeTaxesPaid	0	USD
CY2019Q1	us-gaap	Income Taxes Paid IncomeTaxesPaid	54000	USD
CY2018Q1	us-gaap	Increase Decrease In Accounts Payable And Accrued Liabilities IncreaseDecreaseInAccountsPayableAndAccruedLiabilities	-2735000	USD
CY2019Q1	us-gaap	Increase Decrease In Accounts Payable And Accrued Liabilities IncreaseDecreaseInAccountsPayableAndAccruedLiabilities	-2598000	USD
CY2018Q1	us-gaap	Increase Decrease In Accounts Receivable IncreaseDecreaseInAccountsReceivable	99772000	USD
CY2019Q1	us-gaap	Increase Decrease In Accounts Receivable IncreaseDecreaseInAccountsReceivable	5000	USD
CY2018Q1	us-gaap	Increase Decrease In Deferred Revenue IncreaseDecreaseInDeferredRevenue	110242000	USD
CY2019Q1	us-gaap	Increase Decrease In Deferred Revenue IncreaseDecreaseInDeferredRevenue	0	USD
CY2018Q1	us-gaap	Increase Decrease In Other Operating Assets IncreaseDecreaseInOtherOperatingAssets	-422000	USD
CY2019Q1	us-gaap	Increase Decrease In Other Operating Assets IncreaseDecreaseInOtherOperatingAssets	54000	USD
CY2018Q1	us-gaap	Increase Decrease In Restructuring Reserve IncreaseDecreaseInRestructuringReserve	0	USD
CY2019Q1	us-gaap	Increase Decrease In Restructuring Reserve IncreaseDecreaseInRestructuringReserve	-461000	USD
CY2018Q1	us-gaap	Interest Income Expense Net InterestIncomeExpenseNet	200000	USD
CY2019Q1	us-gaap	Interest Income Expense Net InterestIncomeExpenseNet	2304000	USD
CY2016Q1	us-gaap	Lease Expiration Date1 LeaseExpirationDate1	2023-12-31
CY2018Q4	us-gaap	Leasehold Improvements Gross LeaseholdImprovementsGross	98000	USD
CY2019Q1	us-gaap	Leasehold Improvements Gross LeaseholdImprovementsGross	974000	USD
CY2019Q1	us-gaap	Lessee Operating Lease Liability Payments Due LesseeOperatingLeaseLiabilityPaymentsDue	29416000	USD
CY2019Q1	us-gaap	Lessee Operating Lease Liability Payments Due Year Five LesseeOperatingLeaseLiabilityPaymentsDueYearFive	6535000	USD
CY2019Q1	us-gaap	Lessee Operating Lease Liability Payments Due Year Four LesseeOperatingLeaseLiabilityPaymentsDueYearFour	6350000	USD
CY2019Q1	us-gaap	Lessee Operating Lease Liability Payments Due Year Three LesseeOperatingLeaseLiabilityPaymentsDueYearThree	6165000	USD
CY2019Q1	us-gaap	Lessee Operating Lease Liability Payments Due Year Two LesseeOperatingLeaseLiabilityPaymentsDueYearTwo	5979000	USD
CY2019Q1	us-gaap	Lessee Operating Lease Liability Payments Remainder Of Fiscal Year LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear	4387000	USD
CY2019Q1	us-gaap	Lessee Operating Lease Liability Undiscounted Excess Amount LesseeOperatingLeaseLiabilityUndiscountedExcessAmount	2886000	USD
CY2019Q1	us-gaap	Lessor Operating Lease Payments To Be Received LessorOperatingLeasePaymentsToBeReceived	13920000	USD
CY2019Q1	us-gaap	Lessor Operating Lease Payments To Be Received Five Years LessorOperatingLeasePaymentsToBeReceivedFiveYears	3019000	USD
CY2019Q1	us-gaap	Lessor Operating Lease Payments To Be Received Four Years LessorOperatingLeasePaymentsToBeReceivedFourYears	3047000	USD
CY2019Q1	us-gaap	Lessor Operating Lease Payments To Be Received Remainder Of Fiscal Year LessorOperatingLeasePaymentsToBeReceivedRemainderOfFiscalYear	2067000	USD
CY2019Q1	us-gaap	Lessor Operating Lease Payments To Be Received Three Years LessorOperatingLeasePaymentsToBeReceivedThreeYears	2944000	USD
CY2019Q1	us-gaap	Lessor Operating Lease Payments To Be Received Two Years LessorOperatingLeasePaymentsToBeReceivedTwoYears	2843000	USD
CY2018Q4	us-gaap	Liabilities Liabilities	175798000	USD
CY2019Q1	us-gaap	Liabilities Liabilities	147404000	USD
CY2018Q4	us-gaap	Liabilities And Stockholders Equity LiabilitiesAndStockholdersEquity	498796000	USD
CY2019Q1	us-gaap	Liabilities And Stockholders Equity LiabilitiesAndStockholdersEquity	459534000	USD
CY2018Q4	us-gaap	Liabilities Current LiabilitiesCurrent	14926000	USD
CY2019Q1	us-gaap	Liabilities Current LiabilitiesCurrent	14906000	USD
CY2018Q4	us-gaap	Liabilities Noncurrent LiabilitiesNoncurrent	160872000	USD
CY2019Q1	us-gaap	Liabilities Noncurrent LiabilitiesNoncurrent	132498000	USD
CY2018Q4	us-gaap	Machinery And Equipment Gross MachineryAndEquipmentGross	9693000	USD
CY2019Q1	us-gaap	Machinery And Equipment Gross MachineryAndEquipmentGross	9212000	USD
CY2018Q1	us-gaap	Net Cash Provided By Used In Financing Activities NetCashProvidedByUsedInFinancingActivities	43184000	USD
CY2019Q1	us-gaap	Net Cash Provided By Used In Financing Activities NetCashProvidedByUsedInFinancingActivities	5000	USD
CY2018Q1	us-gaap	Net Cash Provided By Used In Investing Activities NetCashProvidedByUsedInInvestingActivities	-181000	USD
CY2019Q1	us-gaap	Net Cash Provided By Used In Investing Activities NetCashProvidedByUsedInInvestingActivities	-123000	USD
CY2018Q1	us-gaap	Net Cash Provided By Used In Operating Activities NetCashProvidedByUsedInOperatingActivities	-31584000	USD
CY2019Q1	us-gaap	Net Cash Provided By Used In Operating Activities NetCashProvidedByUsedInOperatingActivities	-17435000	USD
CY2018Q1	us-gaap	Net Income Loss NetIncomeLoss	-48743000	USD
CY2019Q1	us-gaap	Net Income Loss NetIncomeLoss	-20865000	USD
CY2018Q1	us-gaap	Noncash Or Part Noncash Acquisition Fixed Assets Acquired1 NoncashOrPartNoncashAcquisitionFixedAssetsAcquired1	79000	USD
CY2019Q1	us-gaap	Noncash Or Part Noncash Acquisition Fixed Assets Acquired1 NoncashOrPartNoncashAcquisitionFixedAssetsAcquired1	8000	USD
CY2018Q1	us-gaap	Nonoperating Income Expense NonoperatingIncomeExpense	-72000	USD
CY2019Q1	us-gaap	Nonoperating Income Expense NonoperatingIncomeExpense	2287000	USD
CY2018Q1	us-gaap	Operating Expenses OperatingExpenses	48935000	USD
CY2019Q1	us-gaap	Operating Expenses OperatingExpenses	23140000	USD
CY2018Q1	us-gaap	Operating Income Loss OperatingIncomeLoss	-48708000	USD
CY2019Q1	us-gaap	Operating Income Loss OperatingIncomeLoss	-22954000	USD
CY2019Q1	us-gaap	Operating Lease Cost OperatingLeaseCost	1600000	USD
CY2019Q1	us-gaap	Operating Lease Liability OperatingLeaseLiability	26513000	USD
CY2018Q4	us-gaap	Operating Lease Liability Current OperatingLeaseLiabilityCurrent	0	USD
CY2019Q1	us-gaap	Operating Lease Liability Current OperatingLeaseLiabilityCurrent	4810000	USD
CY2019Q1	us-gaap	Operating Lease Liability Current OperatingLeaseLiabilityCurrent	4717000	USD
CY2018Q4	us-gaap	Operating Lease Liability Noncurrent OperatingLeaseLiabilityNoncurrent	0	USD
CY2019Q1	us-gaap	Operating Lease Liability Noncurrent OperatingLeaseLiabilityNoncurrent	21703000	USD
CY2019Q1	us-gaap	Operating Lease Liability Noncurrent OperatingLeaseLiabilityNoncurrent	22939000	USD
CY2019Q1	us-gaap	Operating Lease Payments OperatingLeasePayments	1400000	USD
CY2018Q4	us-gaap	Operating Lease Right Of Use Asset OperatingLeaseRightOfUseAsset	0	USD
CY2019Q1	us-gaap	Operating Lease Right Of Use Asset OperatingLeaseRightOfUseAsset	27234000	USD
CY2019Q1	us-gaap	Operating Lease Right Of Use Asset OperatingLeaseRightOfUseAsset	28530000	USD
CY2019Q1	us-gaap	Operating Lease Weighted Average Remaining Lease Term1 OperatingLeaseWeightedAverageRemainingLeaseTerm1	P4Y9M
CY2018Q4	us-gaap	Other Assets Noncurrent OtherAssetsNoncurrent	813000	USD
CY2019Q1	us-gaap	Other Assets Noncurrent OtherAssetsNoncurrent	868000	USD
CY2018Q4	us-gaap	Operating Leases Future Minimum Payments Due OperatingLeasesFutureMinimumPaymentsDue	23000	USD
CY2018Q4	us-gaap	Operating Leases Future Minimum Payments Due Current OperatingLeasesFutureMinimumPaymentsDueCurrent	23000	USD
CY2018Q4	us-gaap	Operating Leases Future Minimum Payments Due Future Minimum Sublease Rentals OperatingLeasesFutureMinimumPaymentsDueFutureMinimumSubleaseRentals	14599000	USD
CY2018Q4	us-gaap	Operating Leases Future Minimum Payments Due In Five Years OperatingLeasesFutureMinimumPaymentsDueInFiveYears	0	USD
CY2018Q4	us-gaap	Operating Leases Future Minimum Payments Due In Four Years OperatingLeasesFutureMinimumPaymentsDueInFourYears	0	USD
CY2018Q4	us-gaap	Operating Leases Future Minimum Payments Due In Three Years OperatingLeasesFutureMinimumPaymentsDueInThreeYears	0	USD
CY2018Q4	us-gaap	Operating Leases Future Minimum Payments Due In Two Years OperatingLeasesFutureMinimumPaymentsDueInTwoYears	0	USD
CY2018Q1	us-gaap	Operating Leases Rent Expense Net OperatingLeasesRentExpenseNet	200000	USD
CY2018Q4	us-gaap	Other Liabilities Current OtherLiabilitiesCurrent	5926000	USD
CY2019Q1	us-gaap	Other Liabilities Current OtherLiabilitiesCurrent	2965000	USD
CY2019Q1	us-gaap	Other Liabilities Current OtherLiabilitiesCurrent	5882000	USD
CY2018Q4	us-gaap	Other Liabilities Noncurrent OtherLiabilitiesNoncurrent	553000	USD
CY2019Q1	us-gaap	Other Liabilities Noncurrent OtherLiabilitiesNoncurrent	553000	USD
CY2018Q1	us-gaap	Other Nonoperating Income Expense OtherNonoperatingIncomeExpense	-272000	USD
CY2019Q1	us-gaap	Other Nonoperating Income Expense OtherNonoperatingIncomeExpense	-17000	USD
CY2018Q4	us-gaap	Other Sundry Liabilities Current OtherSundryLiabilitiesCurrent	278000	USD
CY2019Q1	us-gaap	Other Sundry Liabilities Current OtherSundryLiabilitiesCurrent	384000	USD
CY2019Q1	us-gaap	Payments For Restructuring PaymentsForRestructuring	400000	USD
CY2018Q1	us-gaap	Payments To Acquire Machinery And Equipment PaymentsToAcquireMachineryAndEquipment	181000	USD
CY2019Q1	us-gaap	Payments To Acquire Machinery And Equipment PaymentsToAcquireMachineryAndEquipment	131000	USD
CY2018Q4	us-gaap	Prepaid Expense And Other Assets Current PrepaidExpenseAndOtherAssetsCurrent	3731000	USD
CY2019Q1	us-gaap	Prepaid Expense And Other Assets Current PrepaidExpenseAndOtherAssetsCurrent	3735000	USD
CY2018Q1	us-gaap	Proceeds From Issuance Of Private Placement ProceedsFromIssuanceOfPrivatePlacement	39758000	USD
CY2019Q1	us-gaap	Proceeds From Issuance Of Private Placement ProceedsFromIssuanceOfPrivatePlacement	0	USD
CY2018Q1	us-gaap	Proceeds From Sale Of Property Plant And Equipment ProceedsFromSaleOfPropertyPlantAndEquipment	0	USD
CY2019Q1	us-gaap	Proceeds From Sale Of Property Plant And Equipment ProceedsFromSaleOfPropertyPlantAndEquipment	8000	USD
CY2018Q1	us-gaap	Proceeds From Stock Options Exercised ProceedsFromStockOptionsExercised	4380000	USD
CY2019Q1	us-gaap	Proceeds From Stock Options Exercised ProceedsFromStockOptionsExercised	5000	USD
CY2018Q4	us-gaap	Property Plant And Equipment Gross PropertyPlantAndEquipmentGross	63339000	USD
CY2019Q1	us-gaap	Property Plant And Equipment Gross PropertyPlantAndEquipmentGross	11489000	USD
CY2018Q4	us-gaap	Property Plant And Equipment Net PropertyPlantAndEquipmentNet	52835000	USD
CY2019Q1	us-gaap	Property Plant And Equipment Net PropertyPlantAndEquipmentNet	4632000	USD
CY2019Q1	us-gaap	Property Plant And Equipment Net PropertyPlantAndEquipmentNet	4976000	USD
CY2019Q1	us-gaap	Purchase Obligation PurchaseObligation	1174000	USD
CY2019Q1	us-gaap	Purchase Obligation Due After Fifth Year PurchaseObligationDueAfterFifthYear	0	USD
CY2019Q1	us-gaap	Purchase Obligation Due In Fifth Year PurchaseObligationDueInFifthYear	0	USD
CY2019Q1	us-gaap	Purchase Obligation Due In Fourth Year PurchaseObligationDueInFourthYear	0	USD
CY2019Q1	us-gaap	Purchase Obligation Due In Second Year PurchaseObligationDueInSecondYear	0	USD
CY2019Q1	us-gaap	Purchase Obligation Due In Third Year PurchaseObligationDueInThirdYear	0	USD
CY2019Q1	us-gaap	Purchase Obligation Future Minimum Payments Remainder Of Fiscal Year PurchaseObligationFutureMinimumPaymentsRemainderOfFiscalYear	1174000	USD
CY2018Q1	us-gaap	Research And Development Expense ResearchAndDevelopmentExpense	34706000	USD
CY2019Q1	us-gaap	Research And Development Expense ResearchAndDevelopmentExpense	13296000	USD
CY2018Q1	us-gaap	Restricted Cash Current RestrictedCashCurrent	0	USD
CY2019Q1	us-gaap	Restricted Cash Current RestrictedCashCurrent	1352000	USD
CY2018Q1	us-gaap	Restricted Cash Noncurrent RestrictedCashNoncurrent	4056000	USD
CY2018Q4	us-gaap	Restricted Cash Noncurrent RestrictedCashNoncurrent	4056000	USD
CY2019Q1	us-gaap	Restricted Cash Noncurrent RestrictedCashNoncurrent	2704000	USD
CY2019Q1	us-gaap	Restructuring And Related Cost Cost Incurred To Date1 RestructuringAndRelatedCostCostIncurredToDate1	16100000	USD
CY2019Q1	us-gaap	Restructuring Charges RestructuringCharges	-61000	USD
CY2018Q1	us-gaap	Restructuring Costs RestructuringCosts	0	USD
CY2019Q1	us-gaap	Restructuring Costs RestructuringCosts	-61000	USD
CY2018Q4	us-gaap	Restructuring Reserve Current RestructuringReserveCurrent	461000	USD
CY2019Q1	us-gaap	Restructuring Reserve Current RestructuringReserveCurrent	0	USD
CY2018Q4	us-gaap	Retained Earnings Accumulated Deficit RetainedEarningsAccumulatedDeficit	-597995000	USD
CY2019Q1	us-gaap	Retained Earnings Accumulated Deficit RetainedEarningsAccumulatedDeficit	-615073000	USD
CY2019Q1	us-gaap	Retained Earnings Accumulated Deficit RetainedEarningsAccumulatedDeficit	-594208000	USD
CY2018Q1	us-gaap	Revenues Revenues	227000	USD
CY2019Q1	us-gaap	Revenues Revenues	186000	USD
CY2018Q1	us-gaap	Right Of Use Asset Obtained In Exchange For Operating Lease Liability RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability	0	USD
CY2019Q1	us-gaap	Right Of Use Asset Obtained In Exchange For Operating Lease Liability RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability	28530000	USD
CY2018Q1	us-gaap	Share Based Compensation ShareBasedCompensation	6902000	USD
CY2019Q1	us-gaap	Share Based Compensation ShareBasedCompensation	6205000	USD
CY2019Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Period1 ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1	P4Y
CY2018Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate	0.000
CY2019Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate	0.000
CY2018Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate	0.672
CY2019Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate	0.815
CY2018Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate	0.028
CY2019Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate	0.025
CY2019Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod	325792	shares
CY2018Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod	1093100	shares
CY2019Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod	852975	shares
CY2018Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue	20.67
CY2019Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue	9.48
CY2018Q4	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue	2168908	USD
CY2019Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue	3270000	USD
CY2018Q4	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber	6726715	shares
CY2019Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber	7253048	shares
CY2018Q4	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice	26.82
CY2019Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice	24.69
CY2019Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Aggregate Intrinsic Value ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue	3262000	USD
CY2019Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber	6743549	shares
CY2019Q1	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Exercise Price ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice	25.10
CY2019Q1	us-gaap	Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice	6.41
CY2019Q1	us-gaap	Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice	39.28
CY2019Q1	us-gaap	Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice	13.44
CY2018Q1	us-gaap	Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1 SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1	P6Y
CY2019Q1	us-gaap	Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1 SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1	P6Y
CY2019Q1	us-gaap	Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Exercisable Weighted Average Remaining Contractual Term1 SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageRemainingContractualTerm1	P7Y9M0D
CY2018	us-gaap	Sharebased Compensation Shares Authorized Under Stock Option Plans Exercise Price Range Outstanding Options Weighted Average Remaining Contractual Term2 SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageRemainingContractualTerm2	P7Y4M21D
CY2019Q1	us-gaap	Sharebased Compensation Shares Authorized Under Stock Option Plans Exercise Price Range Outstanding Options Weighted Average Remaining Contractual Term2 SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeOutstandingOptionsWeightedAverageRemainingContractualTerm2	P7Y10M10D
CY2019Q1	us-gaap	Stock Issued During Period Shares Stock Options Exercised StockIssuedDuringPeriodSharesStockOptionsExercised	850	shares
CY2018Q1	us-gaap	Weighted Average Number Of Share Outstanding Basic And Diluted WeightedAverageNumberOfShareOutstandingBasicAndDiluted	38684000	shares
CY2019Q1	us-gaap	Sublease Income SubleaseIncome	733000	USD
CY2018Q1	us-gaap	Stock Issued During Period Value New Issues StockIssuedDuringPeriodValueNewIssues	39758000	USD
CY2018Q1	us-gaap	Stock Issued During Period Value Stock Options Exercised StockIssuedDuringPeriodValueStockOptionsExercised	4399000	USD
CY2019Q1	us-gaap	Stock Issued During Period Value Stock Options Exercised StockIssuedDuringPeriodValueStockOptionsExercised	5000	USD
CY2018Q4	us-gaap	Stockholders Equity StockholdersEquity	322998000	USD
CY2019Q1	us-gaap	Stockholders Equity StockholdersEquity	312130000	USD
CY2017Q4	us-gaap	Stockholders Equity Including Portion Attributable To Noncontrolling Interest StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest	407189000	USD
CY2018Q1	us-gaap	Stockholders Equity Including Portion Attributable To Noncontrolling Interest StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest	409505000	USD
CY2018Q4	us-gaap	Stockholders Equity Including Portion Attributable To Noncontrolling Interest StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest	322998000	USD
CY2019Q1	us-gaap	Stockholders Equity Including Portion Attributable To Noncontrolling Interest StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest	312130000	USD
CY2019Q1	us-gaap	Weighted Average Number Of Share Outstanding Basic And Diluted WeightedAverageNumberOfShareOutstandingBasicAndDiluted	39864000	shares
CY2019Q1	us-gaap	Concentration Risk Credit Risk ConcentrationRiskCreditRisk	<div style="font-family:Times New Roman;font-size:10pt;"><div style="line-height:120%;text-indent:12px;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;font-style:italic;font-weight:bold;">Segment and Concentration of Risks</font></div><div style="line-height:120%;padding-top:12px;text-align:justify;text-indent:32px;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">The Company operates in one segment. The Company’s chief operating decision maker (the “CODM”), its Chief Executive Officer, manages the Company’s operations on a consolidated basis for purposes of allocating resources. When evaluating the Company’s financial performance, the CODM reviews all financial information on a consolidated basis.</font></div><div style="line-height:120%;padding-top:12px;text-align:justify;text-indent:32px;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">Financial instruments that potentially subject the Company to concentration of credit risk consist of cash and cash equivalents and accounts receivable. The Company places its cash equivalents with high credit quality financial institutions and by policy, limits the amount of credit exposure with any one financial institution. Deposits held with banks may exceed the amount of insurance provided on such deposits. The Company has not experienced any losses on its deposits of cash and cash equivalents and its credit risk exposure is up to the extent recorded on the Company's Consolidated Balance Sheet.</font></div><div style="line-height:120%;padding-top:12px;text-align:justify;text-indent:32px;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">The receivable from Roche recorded in prepaid expenses and other current assets in the Condensed Consolidated Balance Sheet are amounts due from a Roche entity located in Switzerland under the License Agreement that became effective January 22, 2014. Revenue recorded in the Condensed Consolidated Statements of Operations consists of reimbursement from Roche for research and development services. The Company's credit risk exposure is up to the extent recorded on the Company's Condensed Consolidated Balance Sheet.</font></div><div style="line-height:120%;padding-top:12px;text-align:justify;text-indent:32px;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;"> As of </font><font style="font-family:inherit;font-size:10pt;">March 31, 2019</font><font style="font-family:inherit;font-size:10pt;">, </font><font style="font-family:inherit;font-size:10pt;">$4.6 million</font><font style="font-family:inherit;font-size:10pt;"> of the Company’s long-lived assets were held in the U.S. and </font><font style="font-family:inherit;font-size:10pt;">none</font><font style="font-family:inherit;font-size:10pt;"> were in Ireland. As of </font><font style="font-family:inherit;font-size:10pt;">December 31, 2018</font><font style="font-family:inherit;font-size:10pt;">, </font><font style="font-family:inherit;font-size:10pt;">$52.8 million</font><font style="font-family:inherit;font-size:10pt;"> of the Company's long-lived assets were held in the U.S. and </font><font style="font-family:inherit;font-size:10pt;">none</font><font style="font-family:inherit;font-size:10pt;"> were in Ireland.</font></div><div style="line-height:120%;padding-top:12px;text-align:justify;text-indent:36px;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">The Company does not own or operate facilities for the manufacture, packaging, labeling, storage, testing or distribution of nonclinical or clinical supplies of any of its drug candidates. The Company instead contracts with and relies on third-parties to manufacture, package, label, store, test and distribute all preclinical development and clinical supplies of our drug candidates, and it plans to continue to do so for the foreseeable future. The Company also relies on third-party consultants to assist in managing these third-parties and assist with its manufacturing strategy.</font></div></div>
CY2019Q1	us-gaap	Use Of Estimates UseOfEstimates	<div style="font-family:Times New Roman;font-size:10pt;"><div style="line-height:120%;padding-top:12px;text-indent:30px;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;font-style:italic;font-weight:bold;">Use of Estimates</font></div><div style="line-height:120%;padding-top:12px;text-align:justify;text-indent:30px;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">The preparation of the Condensed Consolidated Financial Statements in conformity with GAAP requires management to make judgments, estimates and assumptions that affect the reported amounts of assets, liabilities, revenues and expenses, and related disclosures. On an ongoing basis, management evaluates its estimates, including critical accounting policies or estimates related to revenue recognition, share-based compensation and research and development expenses. The Company bases its estimates on historical experience and on various other market specific and other relevant assumptions that management believes to be reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and liabilities that are not readily apparent from other sources. Because of the uncertainties inherent in such estimates, actual results may differ materially from these estimates.</font></div></div>

Files In Submission

Name	View Source	Status
0001559053-19-000013-index-headers.html	Edgar Link	pending
0001559053-19-000013-index.html	Edgar Link	pending
0001559053-19-000013.txt	Edgar Link	pending
0001559053-19-000013-xbrl.zip	Edgar Link	pending
FilingSummary.xml	Edgar Link	unprocessable
Financial_Report.xlsx	Edgar Link	pending
prta-20190331.xml	Edgar Link	completed
prta-20190331.xsd	Edgar Link	pending
prta-20190331_cal.xml	Edgar Link	unprocessable
prta-20190331_def.xml	Edgar Link	unprocessable
prta-20190331_lab.xml	Edgar Link	unprocessable
prta-20190331_pre.xml	Edgar Link	unprocessable
prta2019q110-q.htm	Edgar Link	pending
prta2019q110-qxex311.htm	Edgar Link	pending
prta2019q110-qxex312.htm	Edgar Link	pending
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PROTHENA CORP PUBLIC LTD CO Stock $prta

2019 Q2 Form 10-Q Financial Statement

#000155905319000013 Filed on May 07, 2019

Income Statement

Balance Sheet

Cashflow Statement

Facts In Submission

Files In Submission

$PRTA PROTHENA CORP PUBLIC LTD CO Stock $prta

2019 Q2 Form 10-Q Financial Statement

#000155905319000013 Filed on May 07, 2019

Income Statement

Balance Sheet

Cashflow Statement

Facts In Submission

Files In Submission

$PRTA
PROTHENA CORP PUBLIC LTD CO Stock $prta