2023 Q4 Form 20-F Financial Statement

#000162828024017913 Filed on April 25, 2024

View on sec.gov

Income Statement

Concept 2023 Q4 2023
Revenue $180.0K $3.330M
YoY Change -97.9% -78.68%
Cost Of Revenue
YoY Change
Gross Profit
YoY Change
Gross Profit Margin
Selling, General & Admin $27.13M $53.30M
YoY Change -27.36% -12.62%
% of Gross Profit
Research & Development $43.09M $96.24M
YoY Change -36.5% -36.87%
% of Gross Profit
Depreciation & Amortization $1.872M $4.933M
YoY Change -59.3% -44.53%
% of Gross Profit
Operating Expenses $70.22M $96.24M
YoY Change -33.26% -36.87%
Operating Profit
YoY Change
Interest Expense $53.88M $56.76M
YoY Change -787.21% -170.5%
% of Operating Profit
Other Income/Expense, Net -$6.207M -$8.450M
YoY Change -108.15% -106.1%
Pretax Income -$22.36M -$36.10M
YoY Change -39.28% -61.09%
Income Tax $18.72M $30.53M
% Of Pretax Income
Net Earnings -$40.69M -$66.63M
YoY Change 84.88% 79.76%
Net Earnings / Revenue -22607.22% -2000.84%
Basic Earnings Per Share
Diluted Earnings Per Share -$0.15 -$0.24
COMMON SHARES
Basic Shares Outstanding 271.9M shares
Diluted Shares Outstanding

Balance Sheet

Concept 2023 Q4 2023
SHORT-TERM ASSETS
Cash & Short-Term Investments $328.8M $328.8M
YoY Change -6.66% -6.66%
Cash & Equivalents $191.1M $191.1M
Short-Term Investments $137.7M $137.7M
Other Short-Term Assets $4.308M $4.308M
YoY Change -62.91% -62.91%
Inventory
Prepaid Expenses
Receivables $2.376M $2.376M
Other Receivables $11.75M $11.75M
Total Short-Term Assets $347.2M $347.2M
YoY Change -10.1% -10.1%
LONG-TERM ASSETS
Property, Plant & Equipment $19.36M $19.36M
YoY Change -48.01% -48.01%
Goodwill
YoY Change
Intangibles
YoY Change
Long-Term Investments $321.0M $321.0M
YoY Change 22.98% 22.98%
Other Assets $879.0K $879.0K
YoY Change 7890.91% 7890.91%
Total Long-Term Assets $346.8M $346.8M
YoY Change 9.58% 9.58%
TOTAL ASSETS
Total Short-Term Assets $347.2M $347.2M
Total Long-Term Assets $346.8M $346.8M
Total Assets $694.0M $694.0M
YoY Change -1.23% -1.23%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable $14.64M $14.64M
YoY Change -44.78% -44.78%
Accrued Expenses $29.47M $29.47M
YoY Change 11.95% 11.95%
Deferred Revenue
YoY Change
Short-Term Debt $3.699M $3.699M
YoY Change 57.74% 57.74%
Long-Term Debt Due $3.394M $3.394M
YoY Change -66.49% -66.49%
Total Short-Term Liabilities $51.37M $51.37M
YoY Change -46.98% -46.98%
LONG-TERM LIABILITIES
Long-Term Debt $18.25M $18.25M
YoY Change -46.95% -46.95%
Other Long-Term Liabilities $113.7M $113.7M
YoY Change 2652.7% 2652.7%
Total Long-Term Liabilities $131.9M $131.9M
YoY Change 242.37% 242.37%
TOTAL LIABILITIES
Total Short-Term Liabilities $51.37M $51.37M
Total Long-Term Liabilities $131.9M $131.9M
Total Liabilities $235.7M $229.9M
YoY Change 52.04% 43.31%
SHAREHOLDERS EQUITY
Retained Earnings
YoY Change
Common Stock
YoY Change
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity $464.1M $464.1M
YoY Change
Total Liabilities & Shareholders Equity $694.0M $694.0M
YoY Change -1.23% -1.23%

Cashflow Statement

Concept 2023 Q4 2023
OPERATING ACTIVITIES
Net Income -$40.69M -$66.63M
YoY Change 84.88% 79.76%
Depreciation, Depletion And Amortization $1.872M $4.933M
YoY Change -59.3% -44.53%
Cash From Operating Activities -$40.78M -$105.9M
YoY Change -55.45% -40.76%
INVESTING ACTIVITIES
Capital Expenditures $175.0K $245.0K
YoY Change -66.92% -88.74%
Acquisitions
YoY Change
Other Investing Activities -$104.7M $69.24M
YoY Change 4.92% -165.91%
Cash From Investing Activities -$104.9M $68.99M
YoY Change 4.54% -164.34%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net
YoY Change
Debt Paid & Issued, Net
YoY Change
Cash From Financing Activities -13.76M 78.14M
YoY Change -43.07% -361.99%
NET CHANGE
Cash From Operating Activities -40.78M -105.9M
Cash From Investing Activities -104.9M 68.99M
Cash From Financing Activities -13.76M 78.14M
Net Change In Cash -159.4M 41.22M
YoY Change -26.2% -113.05%
FREE CASH FLOW
Cash From Operating Activities -$40.78M -$105.9M
Capital Expenditures $175.0K $245.0K
Free Cash Flow -$40.96M -$106.2M
YoY Change -55.51% -41.34%

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CY2021 ptv Proceeds From Issue Of Shares To Nci
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CY2023 ptv Payment To Purchase Treasury Stock
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CY2021 ptv Purchase Of Intangible Assets But Not Yet Paid
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CY2021 ptv Purchase Of Property Plant And Equipment Against Trade And Other Payables
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CY2022 ptv Leasehold Improvements Purchased Through Lease Incentives
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CY2021 ptv Leasehold Improvements Purchased Through Lease Incentives
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CY2022 ptv Conversion Of Subsidiary Convertible Note Into Preferred Share Liabilities
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CY2021 ptv Conversion Of Subsidiary Convertible Note Into Preferred Share Liabilities
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CY2023 ifrs-full Disclosure Of Material Accounting Policy Information Explanatory
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Material Accounting Policies<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Description of Business</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Health plc (the “Parent”) is a public company incorporated, domiciled and registered in the United Kingdom (“UK”). The registered number is 09582467 and the registered address is 13th Floor, One Angel Court, London, EC2R 7HJ, United Kingdom.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Parent and its subsidiaries are together referred to as the “Group”.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The accounting policies set out below have, unless otherwise stated, been applied consistently to all periods presented in these group financial statements.</span></div><div style="margin-bottom:5pt;margin-top:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For presentation of the Consolidated Statement of Comprehensive Income/(Loss), the Group uses a classification based on the function of expenses, rather than based on their nature, as it is more representative of the format used for internal reporting and management purposes and is consistent with international practice.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain amounts in the Consolidated Financial Statements and accompanying notes may not add due to rounding. All percentages have been calculated using unrounded amounts.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basis of Measurement </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Consolidated Financial Statements are prepared on the historical cost basis except that the following assets and liabilities are stated at their fair value: investments held at fair value, investments in notes from associates and liabilities classified as fair value through the profit or loss. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Use of Judgments and Estimates </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In preparing the Consolidated Financial Statements, management has made judgements, estimates and assumptions that affect the application of the Group’s accounting policies and the reported amounts of assets, liabilities, income and expenses. Actual results may differ from these estimates. Estimates and underlying assumptions are reviewed on an on-going basis.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Significant estimation is applied in determining the following:</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Financial instruments valuations (see Note 18. Financial Instruments): In accordance with IFRS 9, the Group carries certain financial assets and financial liabilities at fair value, with changes in fair value through profit and loss ("FVTPL"). Valuation of the aforementioned financial instruments (assets and liabilities) includes making significant estimates, specifically determining the appropriate valuation methodology and making certain estimates such as the future expected returns on the financial instrument in different scenarios, appropriate discount rate, volatility, and term to exit. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Significant judgement is also applied in determining the following:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Whether financial instruments should be classified as liability or equity (see Note 16. Subsidiary Preferred Shares.). The judgement includes an assessment of whether the financial instruments include contractual obligations of the Group to deliver cash or other financial assets or to exchange financial assets or financial liabilities with another party, and whether those obligations could be settled by the Group exchanging a fixed amount of cash or other financial assets for a fixed number of its own equity instruments. Further information about these critical judgements and estimates is included below under Financial Instruments.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Whether the power to control investees exists (see Note 5. Investments Held at Fair Value and Note 6. Investments in Associates and accounting policy with regard to Subsidiaries below). The judgement includes an assessment of whether the Group has (i) power over the investee; (ii) exposure, or rights, to variable returns from its involvement with the investee; and (iii) the ability to use its power over the investee to affect the amount of its own returns. The Group considers among others its voting shares, shareholder agreements, ability to appoint board members, representation on the board, rights to appoint management, de facto control, investee dependence on the Group, etc. If the power to control the investee exists, it consolidates the financial statements of such investee in the Consolidated Financial Statements of the Group. Upon issuance of new shares in an investee and/or a change in any shareholders or governance agreements, the Group reassesses its ability to control the investee based on the revised voting interest, revised board composition and revised subsidiary governance and management structure. When such new circumstances result in the Group losing its power to control the investee, the investee is deconsolidated. On March 1 2023 Vedanta was deconsolidated. Although the Group holds 47% of the voting rights and the other shareholders are widely dispersed, the Group does not have de facto control because the investor rights agreement stipulates that the relevant activities of Vedanta are directed by Vedanta's Board and the Group does not control Vedanta's Board decision making. Voting rights are not the dominant factor for directing Vedanta's relevant activities.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Whether the Group has significant influence over financial and operating policies of investees in order to determine if the Group should account for its investment as an associate based on IAS 28 or a financial instrument based on IFRS 9. (refer to Note 5. Investments Held at Fair Value and Note 6. Investments in Associates ). This judgement includes, among others, an assessment whether the Group has representation on the board of directors of the investee, whether the Group participates in the policy making processes of the investee, whether there is any interchange of managerial personnel, whether there is any essential technical information provided to the investee and if there are any transactions between the Group and the investee.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Upon determining that the Group does have significant influence over the financial and operating policies of an investee, if the Group holds more than a single instrument issued by its equity-accounted investee, judgement is required to determine whether the additional instrument forms part of the investment in the associate, which is accounted for under IAS 28 and </span></div><div style="padding-left:11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">scoped out of IFRS 9, or it is a separate financial instrument that falls in the scope of IFRS 9. This judgement includes an assessment of the characteristics of the financial instrument of the investee held by the Group and whether such financial instrument provides access to returns underlying an ownership interest.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">When the Group has other investments in an equity accounted investee that are not accounted for under IAS 28, judgement is required in determining if such investments constitute long-term interests ("LTI") for the purposes of IAS 28. This determination is based on the individual facts and circumstances and characteristics of each investment, but is driven, among other factors, by the intention and likelihood to settle the instrument through redemption or repayment in the foreseeable future, and whether or not the investment is likely to be converted to common stock or other equity instruments. After considering the individual facts and circumstances of the Group’s investment in its associate's preferred stock in the manner described above, including the long-term nature of such investment, the ability of the Group to convert its preferred stock investment to an investment in common shares and the likelihood of such conversion, the Group concluded that such investment was considered a long term interest.</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">In determining the appropriate accounting treatment for the Royalty Purchase Agreement, management applied significant judgement (refer to Note 17. Sale of Future Royalties Liability).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2023, the Group had cash and cash equivalents of $191,081 and short-term investments of $136,062. Considering the Group’s financial position as of December 31, 2023, and its principal risks and opportunities, the Group prepared a going concern analysis covering a period of at least the twelve-month period from the date of signing the Consolidated Financial Statements ("the going concern period") utilizing realistic scenarios and applying a severe but plausible downside scenario. Even under the downside scenario, the analysis demonstrates the Group continues to maintain sufficient liquidity headroom and continues to comply with all financial obligations. The Board of Directors believe the Group and the Parent is adequately resourced to continue in operational existence for at least the twelve-month period from the date of signing the Consolidated Financial Statements. Accordingly, the Board of Directors considered it appropriate to adopt the going concern basis of accounting in preparing the Consolidated Financial Statements and the PureTech Health plc Financial Statements. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basis of consolidation</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Consolidated Financial Statements as of December 31, 2023 and 2022, and for each of the years ended December 31, 2023, 2022 and 2021, comprises PureTech Health plc and its consolidated subsidiaries. Intra-group balances and transactions, and any unrealized income and expenses arising from intra-group transactions, are eliminated.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiaries </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As used in these financial statements, the term subsidiaries refers to entities that are controlled by the Group. Under applicable accounting rules, the Group controls an entity when it is exposed to, or has the rights to, variable returns from its involvement with the entity and has the ability to affect those returns through its power over the entity. In assessing control, the Group takes into consideration potential voting rights, board representation, shareholders' agreements, ability to appoint board of directors and management, de facto control and other related factors. The financial statements of subsidiaries are included in the Consolidated Financial Statements from the date that control commences until the date that control ceases. Losses applicable to the non-controlling interests in a subsidiary are allocated to the non-controlling interests even if doing so causes the non-controlling interests to have a deficit balance.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">A list of all current and former subsidiaries organized with respect to classification as of December 31, 2023, and the Group’s total voting percentage, based on outstanding voting common and preferred shares as of December 31, 2023, 2022 and 2021, is outlined below. All current subsidiaries are domiciled within the United States and conduct business activities solely within the United States. </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:43.142%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.990%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.990%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.990%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.990%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.990%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.996%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="24" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Voting percentage at December 31, through the holdings in</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Common</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%"> Preferred</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Common</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%"> Preferred</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Common</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%"> Preferred</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Subsidiary operating companies</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio Therapeutics, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega, Inc. (indirectly held through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">77.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">77.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">77.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT, Inc. (formerly Ariya Therapeutics, Inc.)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT 100, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Management, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Health LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Deconsolidated former subsidiary operating companies</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde Health, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2,5</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">40.2</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">40.2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Akili Interactive Labs, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2,6</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14.6</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">26.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna Therapeutics, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2,6</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2, 4</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences Securities Corp. (indirectly held through Vedanta)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2, 4</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vor Biopharma Inc</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">.2,6</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3.9</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Nontrading holding companies</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.4pt;font-weight:400;line-height:120%">Endra Holdings, LLC (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.46pt;font-weight:400;line-height:120%;position:relative;top:-2.94pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.4pt;font-weight:400;line-height:120%">Ensof Holdings, LLC (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.46pt;font-weight:400;line-height:120%;position:relative;top:-2.94pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Securities Corp.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Securities II Corp.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Inactive subsidiaries</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Appeering, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Commense Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99.1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Enlight Biosciences, LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8pt;font-weight:400;line-height:120%">Ensof Biosystems, Inc. (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.2pt;font-weight:400;line-height:120%;position:relative;top:-2.8pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">57.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica, LLC </span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">56.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">56.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">56.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Knode Inc. (indirectly held through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Libra Biosciences, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Mandara Sciences, LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">98.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">98.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">98.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tal Medical, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    On October 30, 2023, Gelesis ceased operations and filed a voluntary petition for relief under the United States bankruptcy code. See Note 6. Investments in Associates for details.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Registered address is Corporation Trust Center, 1209 Orange St., Wilmington, DE 19801, USA.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Registered address is 2711 Centerville Rd., Suite 400, Wilmington, DE 19808, USA.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">4    On March 1, 2023, the Group lost control over Vedanta and Vedanta was deconsolidated from the Group’s financial statements, resulting in only the profits and losses generated by Vedanta through the deconsolidation date being included in the Group’s Consolidated Statement of Comprehensive Income/(Loss). See Notes 5. Investments Held at Fair Value for further details about the accounting for the investments in Vedanta subsequent to deconsolidation.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">5    On May 25, 2022, the Group lost control over Sonde and Sonde was deconsolidated from the Group’s financial statements, resulting in only the profits and losses generated by Sonde through the deconsolidation date being included in the Group’s Consolidated Statement of Comprehensive Income/(Loss). See Notes 5. Investments Held at Fair Value and 6. Investments in Associates for further details about the accounting for the investments in Sonde subsequent to deconsolidation.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">6    See Notes 5. Investments Held at Fair Value and 6. Investments in Associates for additional discussion on the Group's investment held in Akili, Karuna and Vor.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">7    Follica became inactive during 2023.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span><br/></span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in Subsidiary Ownership and Loss of Control </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in the Group’s interest in a subsidiary that do not result in a loss of control are accounted for as equity transactions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Where the Group loses control of a subsidiary, the assets and liabilities are derecognized along with any related non-controlling interest (“NCI”). Any interest retained in the former subsidiary is measured at fair value when control is lost. Any resulting gain or loss is recognized as profit or loss in the Consolidated Statement of Comprehensive Income/(Loss).</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Associates </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As used in these financial statements, the term associates are those entities in which the Group has no control but maintains significant influence over the financial and operating policies. Significant influence is presumed to exist when the Group holds between 20 and 50 percent of the voting power of an entity, unless it can be clearly demonstrated that this is not the case. The Group evaluates if it maintains significant influence over associates by assessing if the Group has the power to participate in the financial and operating policy decisions of the associate.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Application of the Equity Method to Associates </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Associates are accounted for using the equity method (equity accounted investees) and are initially recognized at cost, or if recognized upon deconsolidation, they are initially recorded at fair value at the date of deconsolidation. The Consolidated </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Statements include the Group’s share of the total comprehensive income or loss of equity accounted investees, from the date that significant influence commences until the date that significant influence ceases. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">To the extent the Group holds interests in associates that are not providing access to returns underlying ownership interests, the instrument is accounted for in accordance with IFRS 9 as investments held at fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">When the Group’s share of losses exceeds its equity method investment in the investee, losses are applied against long-term interests, which are investments accounted for under IFRS 9. Investments are determined to be long-term interests when they are long-term in nature and in substance they form part of the Group's net investment in that associate. This determination is impacted by many factors, among others, whether settlement by the investee through redemption or repayment is planned or likely in the foreseeable future, whether the investment can be converted and/or is likely to be converted to common stock or other equity instrument and other factors regarding the nature of the investment. Whilst this assessment is dependent on many specific facts and circumstances of each investment, typically conversion features whereby the investment is likely to convert to common stock or other equity instruments would point to the investment being a long-term interest. Similarly, where the investment is not planned or likely to be settled through redemption or repayment in the foreseeable future, this would indicate that the investment is a long-term interest. When the net investment in the associate, which includes the Group’s investments in other long-term interests, is reduced to nil, recognition of further losses is discontinued except to the extent that the Group has incurred legal or constructive obligations or made payments on behalf of an investee.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has adopted the amendments to IAS 28 Investments in Associates that addresses the dual application of IAS 28 and IFRS 9 when equity method losses are applied against long-term interests. The amendments provide the annual sequence in which both standards are to be applied in such a case. The Group has applied the equity method losses to the long-term interests presented as part of Investments held at fair value subsequent to remeasuring such investments to their fair value at balance sheet date.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sale of Future Royalties Liability</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group accounts for the sale of future royalties liability as a financial liability, as it continues to hold the rights under the royalty bearing licensing agreement and has a contractual obligation to deliver cash to an investor for a portion of the royalty it receives. Interest on the sale of future royalties liability is recognized using the effective interest rate over the life of the related royalty stream.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The sale of future royalties liability and the related interest expense are based on the Group’s current estimates of future royalties expected to be paid over the life of the arrangement. Forecasts are updated periodically as new data is obtained. Any increases, decreases or a shift in timing of estimated cash flows require the Group to re-calculate the amortized cost of the sale of future royalties liability as the present value of the estimated future contractual cash flows that are discounted at the liability’s original effective interest rate. The adjustment is recognized immediately in profit or loss as income or expense.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Instruments </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Classification </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group classifies its financial assets in the following measurement categories:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Those to be measured subsequently at fair value either through other comprehensive income "FVOCI", or through profit or loss "FVTPL", and</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Those to be measured at amortized cost.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The classification depends on the Group’s business model for managing the financial assets and the contractual terms of the cash flows.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For assets measured at fair value, gains and losses are recorded in profit or loss. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Measurement </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">At initial recognition, the Group measures a financial asset at its fair value plus, in the case of a financial asset not at FVTPL, transaction costs that are directly attributable to the acquisition of the financial asset. Transaction costs of financial assets that are carried at FVTPL are expensed.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Impairment </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group assesses on a forward-looking basis the expected credit losses associated with its debt instruments carried at amortized cost. For trade receivables, the Group applies the simplified approach permitted by IFRS 9, which requires expected lifetime losses to be recognized from initial recognition of the receivables.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Financial Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s financial assets consist of cash and cash equivalents, investments in debt securities, trade and other receivables, notes, restricted cash deposits and investments in equity securities. The Group’s financial assets are virtually all classified into the following categories: investments held at fair value, notes, trade and other receivables, short-term investments and cash and cash equivalents. The Group determines the classification of financial assets at initial recognition depending on the purpose for which the financial assets were acquired.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value are investments in equity instruments. Such investments consist of the Group's minority interest holdings where the Group has no significant influence or preferred share investments that are not providing access to returns underlying ownership interests and are categorized as debt instruments that are presented at fair value through profit and loss because the amounts receivable do not represent solely payments of principal and interest. These financial assets are initially measured at fair value and subsequently re-measured at fair value at each reporting date. The Group has elected to record the changes in fair values for the financial assets falling under this category through profit and loss. Please refer to Note 5. Investments Held at Fair Value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in the fair value of financial assets at FVTPL are recognized in other income/(expense) in the Consolidated Statement of Comprehensive Income/(Loss) as applicable. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The notes from an associate, since their contractual terms do not consist solely of cash flow payments of principal and interest on the principal amount outstanding, are initially and subsequently measured at fair value, with changes in fair value recognized through profit and loss.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and cash equivalents consist of demand deposits with banks and other financial institutions and highly liquid instruments with original maturities of three months or less at the date of purchase. Cash and cash equivalents are carried at cost, which approximates their fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term investments consist of short-term US treasury bills that are held to maturity. The contractual terms consist solely of payment of the principal and interest and the Group's business model is to hold the treasury bills to maturity. As such, such short-term investments are recorded at amortized cost. As of balance sheet date, amortized cost approximated the fair value of such short-term investments.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables are non-derivative financial assets with fixed and determinable payments that are not quoted on active markets. These financial assets are carried at the amounts expected to be received less any expected lifetime losses. Such losses are determined taking into account previous experience, credit rating and economic stability of counterparty and economic conditions. When a trade receivable is determined to be uncollectible, it is written off against the available provision. As of balance sheet date, the Group did not record any such expected lifetime losses related to the outstanding trade and other receivable balances. Trade and other receivables are included in current assets, unless maturities are greater than 12 months after the end of the reporting period.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Financial Liabilities </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s financial liabilities primarily consist of trade and other payables, and preferred shares. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The majority of the Group’s subsidiaries have preferred shares and certain notes payable with embedded derivatives, which are classified as current liabilities. When the Group has preferred shares and notes with embedded derivatives that qualify for bifurcation, the Group has elected to account for the entire instrument as FVTPL after determining under IFRS 9 that the instrument qualifies to be accounted for under such FVTPL method.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group derecognizes a financial liability when its contractual obligations are discharged, cancelled or expire.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity Instruments Issued by the Group </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial instruments issued by the Group are treated as equity only to the extent that they meet the following two conditions, in accordance with IAS 32:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:4.26pt">They include no contractual obligations upon the Group to deliver cash or other financial assets or to exchange financial assets or financial liabilities with another party under conditions that are potentially unfavorable to the Group; and</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:4.26pt">Where the instrument will or may be settled in the Group’s own equity instruments, it is either a non-derivative that includes no obligation to deliver a variable number of the Group’s own equity instruments or is a derivative that will be settled by the Group exchanging a fixed amount of cash or other financial assets for a fixed number of its own equity instruments.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">To the extent that this definition is not met, the financial instrument is classified as a financial liability. Where the instrument so classified takes the legal form of the Group’s own shares, the amounts presented in the Group's shareholders' equity exclude amounts in relation to those shares.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in the fair value of liabilities at FVTPL are recognized in net finance income /(costs) in the Consolidated Statement of Comprehensive Income/(Loss) as applicable. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">IFRS 15, Revenue from Contracts with Customers </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The standard establishes a five-step principle-based approach for revenue recognition and is based on the concept of recognizing an amount that reflects the consideration for performance obligations only when they are satisfied and the control of goods or services is transferred.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The majority of the Group’s contract revenue is generated from licenses and services, some of which are part of collaboration arrangements. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Management reviewed contracts where the Group received consideration in order to determine whether or not they should be accounted for in accordance with IFRS 15. To date, the Group has entered into transactions that generate revenue and meet the scope of either IFRS 15 or IAS 20 Accounting for Government Grants. Contract revenue is recognized at either a point-in-time or over time, depending on the nature of the performance obligations.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group accounts for agreements that meet the definition of IFRS 15 by applying the following five step model:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Identify the contract(s) with a customer – A contract with a customer exists when (i) the Group enters into an enforceable contract with a customer that defines each party’s rights regarding the goods or services to be transferred and identifies the payment terms related to those goods or services, (ii) the contract has commercial substance and, (iii) the Group determines that collection of substantially all consideration for goods or services that are transferred is probable based on the customer’s intent and ability to pay the promised consideration.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Identify the performance obligations in the contract – Performance obligations promised in a contract are identified based on the goods or services that will be transferred to the customer that are both capable of being distinct, whereby the customer can benefit from the good or service either on its own or together with other resources that are readily available from third parties or from the Group, and are distinct in the context of the contract, whereby the transfer of the goods or services is separately identifiable from other promises in the contract.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Determine the transaction price – The transaction price is determined based on the consideration to which the Group will be entitled in exchange for transferring goods or services to the customer. To the extent the transaction price includes variable consideration, the Group estimates the amount of variable consideration that should be included in the transaction price utilizing either the expected value method or the most likely amount method depending on the nature of the variable consideration. Variable consideration is included in the transaction price if, in the Group’s judgement, it is probable that a significant future reversal of cumulative revenue under the contract will not occur. </span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Allocate the transaction price to the performance obligations in the contract – If the contract contains a single performance obligation, the entire transaction price is allocated to the single performance obligation. Contracts that contain multiple performance obligations require an allocation of the transaction price to each performance obligation based on a relative standalone selling price basis. </span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Recognize revenue when (or as) the Group satisfies a performance obligation – The Group satisfies performance obligations either over time or at a point in time as discussed in further detail below. Revenue is recognized at the time the related performance obligation is satisfied by transferring a promised good or service to a customer.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue generated from services agreements (typically where licenses and related services were combined into one performance obligation) is determined to be recognized over time when it can be determined that the services meet one of the following: (a) the customer simultaneously receives and consumes the benefits provided by the entity’s performance as the entity performs; (b) the entity’s performance creates or enhances an asset that the customer controls as the asset is created or enhanced; or (c) the entity’s performance does not create an asset with an alternative use to the entity and the entity has an enforceable right to payment for performance completed to date.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">It was determined that the Group has contracts that meet criteria (a), since the customer simultaneously receives and consumes the benefits provided by the Group’s performance as the Group performs. Therefore revenue is recognized over time using the input method based on costs incurred to date as compared to total contract costs. The Group believes that in research and development service type agreements using costs incurred to date represents the most faithful depiction of the entity’s performance towards complete satisfaction of a performance obligation.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue from licenses that are not part of a combined performance obligation are recognized at a point in time due to the licenses relating to intellectual property that has significant stand-alone functionality and as such represent a right to use the entity's intellectual property as it exists at the point in time at which the license is granted.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Royalty income received in respect of licensing agreements when the license of intellectual property is the predominant item in the arrangement is recognized as the related third-party sales in the licensee occur.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amounts that are receivable or have been received per contractual terms but have not been recognized as revenue since performance has not yet occurred or has not yet been completed are recorded as deferred revenue. The Group classifies as non-current deferred revenue amounts received for which performance is expected to occur beyond one year or one operating cycle.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Grant Revenue</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group recognizes grants from governmental agencies as grant revenue in the Consolidated Statement of Comprehensive Income/(Loss), gross of the expenditures that were related to obtaining the grant, when there is reasonable assurance that the Group will comply with the conditions within the grant agreement and there is reasonable assurance that payments under the grants will be received. The Group evaluates the conditions of each grant as of each reporting date to ensure that the Group has reasonable assurance of meeting the conditions of each grant arrangement and that it is expected that the grant payment will be received as a result of meeting the necessary conditions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group submits qualifying expenses for reimbursement after the Group has incurred the research and development expense. The Group records an unbilled receivable upon incurring such expenses. In cases in which the grant revenue is received prior to the expenses being incurred or recognized, the amounts received are deferred until the related expense is incurred and/or recognized. Grant revenue is recognized in the Consolidated Statement of Comprehensive Income/(Loss) at the time in which the Group recognizes the related reimbursable expense for which the grant is intended to compensate.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Functional and Presentation Currency </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Consolidated Financial Statements are presented in United States dollars (“US dollars”). The functional currency of all members of the Group is the U.S. dollar. The Group's share in foreign exchange differences in associates were reported in other comprehensive income/(loss).</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Foreign Currency </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transactions in foreign currencies are translated to the respective functional currencies of Group entities at the foreign exchange rate ruling at the date of the transaction. Monetary assets and liabilities denominated in foreign currencies at the balance sheet date are retranslated to the functional currency at the foreign exchange rate ruling at that date. Foreign exchange differences arising on remeasurement are recognized in the Consolidated Statement of Comprehensive Income/(Loss). Non-monetary assets and liabilities that are measured in terms of historical cost in a foreign currency are translated using the exchange rate at the date of the transaction. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share Capital </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Ordinary shares are classified as equity. The Group's equity is comprised of share capital, share premium, merger reserve, other reserve, translation reserve, and retained earnings/accumulated deficit.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Treasury Shares</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Treasury shares are recognized at cost and are deducted from shareholders' equity. No gain or loss is recognized in profit and loss for the purchase, sale, re-issue or cancellation of the Group's own equity shares.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Property and Equipment </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Property and equipment is stated at cost less accumulated depreciation and any accumulated impairment losses. Cost includes expenditures that are directly attributable to the acquisition of the asset. Assets under construction represent leasehold improvements and machinery and equipment to be used in operations or research and development activities. When parts of an item of property and equipment have different useful lives, they are accounted for as separate items (major components) of property and equipment. Depreciation is calculated using the straight-line method over the estimated useful life of the related asset: </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:47.384%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:50.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Laboratory and manufacturing equipment</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2-8 years</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Furniture and fixtures</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7 years</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Computer equipment and software</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1-5 years</span></div></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Leasehold improvements</span></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5-10 years, or the remaining term of the lease, if shorter</span></div></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation methods, useful lives and residual values are reviewed at each balance sheet date.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Intangible Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Intangible assets, which include purchased patents and licenses with finite useful lives, are carried at historical cost less accumulated amortization, if amortization has commenced. Intangible assets with finite lives are amortized from the time they are available for their intended use. Amortization is calculated using the straight-line method to allocate the costs of patents and licenses over their estimated useful lives. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development intangible assets, which are still under development and have accordingly not yet obtained marketing approval, are presented as In-Process Research and Development (IPR&amp;D). The cost of IPR&amp;D represents upfront payments as well as additional contingent payments based on development, regulatory and sales milestones related to certain license agreement where the Group licenses IP from a third party. These milestones are capitalized as the milestone is triggered. See Note 25. Commitments and Contingencies. IPR&amp;D is not amortized since it is not yet available for its intended use, but it is evaluated for potential impairment on an annual basis or more frequently when facts and circumstances warrant.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment of Non-Financial Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group reviews the carrying amounts of its property and equipment and intangible assets at each reporting date to determine whether there are indicators of impairment. If any such indicators of impairment exist, then an asset’s recoverable amount is estimated. The recoverable amount is the higher of an asset’s fair value less cost of disposal and value in use.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s IPR&amp;D intangible assets are not yet available for their intended use. As such, they are tested for impairment at least annually. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">An impairment loss is recognized when an asset’s carrying amount exceeds its recoverable amount. For the purposes of impairment testing, assets are grouped at the lowest levels for which there are largely independent cash flows. If a non- financial asset instrument is impaired, an impairment loss is recognized in the Consolidated Statement of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments in associates are considered impaired if, and only if, objective evidence indicates that one or more events, which occurred after the initial recognition, have had an impact on the future cash flows from the net investment and that impact can be reliably estimated. If an impairment exists, the Group measures an impairment by comparing the carrying value of the net investment in the associate to its recoverable amount and recording any excess as an impairment loss. See Note 6. Investments in Associates for impairment recorded in respect of an investment in associate during the year ended December 31, 2022.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Employee Benefits </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Short-Term Employee Benefits </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term employee benefit obligations are measured on an undiscounted basis and expensed as the related service is provided. A liability is recognized for the amount expected to be paid if the Group has a present legal or constructive obligation due to past service provided by the employee, and the obligation can be estimated reliably.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Defined Contribution Plans </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">A defined contribution plan is a post-employment benefit plan under which an entity pays fixed contributions into a separate entity and has no legal or constructive obligation to pay further amounts. Obligations for contributions to defined contribution plans are recognized as an employee benefit expense in the periods during which related services are rendered by employees. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Share-based Payments </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment arrangements, in which the Group receives goods or services as consideration for its own equity instruments, are accounted for as equity-settled share-based payment transactions (except certain restricted stock units - see below) in accordance with IFRS 2, regardless of how the equity instruments are obtained by the Group. The grant date fair value of employee share-based payment awards is recognized as an expense with a corresponding increase in equity over the requisite service period related to the awards. The amount recognized as an expense is adjusted to reflect the actual number of awards for which the related service and non-market performance conditions are expected to be met, such that the amount ultimately recognized as an expense is based on the number of awards that do meet the related service and non-market performance conditions at the vesting date. For share-based payment awards with market conditions, the grant date fair value is measured to reflect such conditions and there is no true-up for differences between expected and actual outcomes.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain restricted stock units are treated as liability settled awards starting in 2021. Such awards are remeasured at every reporting date until settlement date and are recognized as compensation expense over the requisite service period. Differences in remeasurement are recognized in profit and loss. The cumulative cost that will ultimately be recognized in respect of these awards will equal to the amount at settlement. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the awards is measured using option pricing models and other appropriate models, which take into account the terms and conditions of the awards granted. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Development Costs </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expenditures on research activities are recognized as incurred in the Consolidated Statement of Comprehensive Income/(Loss). In accordance with IAS 38, development costs are capitalized only if the expenditure can be measured reliably, the product or process is technically and commercially feasible, future economic benefits are probable, the Group can demonstrate its ability to use or sell the intangible asset, the Group intends to and has sufficient resources to complete development and to use or sell the asset, and it is able to measure reliably the expenditure attributable to the intangible asset during its development. The point at which technical feasibility is determined to have been reached is, generally, when regulatory approval has been received where applicable. Management determines that commercial viability has been reached when a clear market and pricing point have been identified, which may coincide with achieving meaningful recurring sales. Otherwise, the development expenditure is recognized </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">as incurred in the Consolidated Statement of Comprehensive Income/(Loss). As of balance sheet date, the Group has not capitalized any development costs.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Provisions </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">A provision is recognized in the Consolidated Statement of Financial Position when the Group has a present legal or constructive obligation due to a past event that can be reliably measured, and it is probable that an outflow of economic benefits will be required to settle the obligation. Provisions are determined by discounting the expected future cash flows at a pre-tax rate that reflects risks specific to the liability.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Leases</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group leases real estate for use in operations. These leases have lease terms of approximately 10 years. The Group includes options that are reasonably certain to be exercised as part of the determination of the lease term. The group determines if an arrangement is a lease at inception of the contract in accordance with guidance detailed in IFRS 16. Right-of-use (ROU) assets represent the Group’s right to use an underlying asset for the lease term and lease liabilities represent the Group's obligation to make lease payments arising from the lease. Operating lease ROU assets and lease liabilities are recognized at commencement date based on the present value of the lease payments over the lease term. As most of the Group's leases do not provide an implicit rate, the Group used its estimated incremental borrowing rate, based on information available at commencement date, in determining the present value of future payments. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s leases are virtually all leases of real estate.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has elected to account for lease payments as an expense on a straight-line basis over the life of the lease for: </span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Leases with a term of 12 months or less and containing no purchase options; and </span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Leases where the underlying asset has a value of less than $5,000. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The right-of-use asset is depreciated on a straight-line basis and the lease liability gives rise to an interest charge. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance Income and Finance Costs </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income consists of interest income on funds invested in money market funds and U.S. treasuries. Finance income is recognized as it is earned. Finance costs consist mainly of loan, notes and lease liability interest expenses, interest expense due to accretion of and adjustment to sale of future royalties liability as well as the changes in the fair value of financial liabilities carried at FVTPL (such changes can consist of finance income when the fair value of such financial liabilities decreases).</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax on the profit or loss for the year comprises current and deferred income tax. In accordance with IAS 12, tax is recognized in the Consolidated Statement of Comprehensive Income/(Loss) except to the extent that it relates to items recognized directly in equity.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current income tax is the expected tax payable or receivable on the taxable income or loss for the year, using tax rates enacted or substantially enacted at the reporting date, and any adjustment to tax payable in respect of previous years.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax is recognized due to temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for taxation purposes. Deferred tax assets are recognized for unused tax losses, unused tax credits and deductible temporary differences to the extent that it is probable that future taxable profits will be available against which they can be used. Deferred tax assets with respect to investments in associates are recognized only to the extent that it is probable the temporary difference will reverse in the foreseeable future and taxable profit will be available against which the temporary difference can be utilized. Deferred tax assets are reviewed at each reporting date and are reduced to the extent that it is no longer probable that the related tax benefit will be realized.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax is measured at the tax rates that are expected to be applied to temporary differences when they reverse, using tax rates enacted or substantively enacted at the reporting date.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred income tax assets and liabilities are offset when there is a legally enforceable right to offset current tax assets against current tax liabilities and when the deferred income tax assets and liabilities relate to income taxes levied by the same taxation authority on either the same taxable entity or different taxable entities where there is an intention to settle the balances on a net basis.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair Value Measurements </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s accounting policies require that certain financial assets and certain financial liabilities be measured at their fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group uses valuation techniques that are appropriate in the circumstances and for which sufficient data are available to measure fair value, maximizing the use of relevant observable inputs and minimizing the use of unobservable inputs. Fair values are categorized into different levels in a fair value hierarchy based on the inputs used in the valuation techniques as follows:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 1: quoted prices (unadjusted) in active markets for identical assets or liabilities.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 2: inputs other than quoted prices included in Level 1 that are observable for the asset or liability, either directly (i.e. as prices) or indirectly (i.e. derived from prices).</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 3: inputs for the asset or liability that are not based on observable market data (unobservable inputs).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group recognizes transfers between levels of the fair value hierarchy at the end of the reporting period during which the change has occurred.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The carrying amount of cash and cash equivalents, accounts receivable, restricted cash, deposits, accounts payable, accrued expenses and other current liabilities in the Group’s Consolidated Statement of Financial Position approximates their fair value because of the short maturities of these instruments. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating Segments </span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating segments are reported in a manner that is consistent with the internal reporting provided to the chief operating decision maker (“CODM”). The CODM reviews discrete financial information for the operating segments in order to assess their </span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">performance and is responsible for making decisions about resources allocated to the segments. The CODM has been identified as the Group’s Board of Directors.</span></div>
CY2023Q4 ifrs-full Cash And Cash Equivalents
CashAndCashEquivalents
191081000 usd
CY2023Q4 ptv Short Term Investment
ShortTermInvestment
136062000 usd
CY2023 ifrs-full Description Of Accounting Policy For Subsidiaries Explanatory
DescriptionOfAccountingPolicyForSubsidiariesExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiaries </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As used in these financial statements, the term subsidiaries refers to entities that are controlled by the Group. Under applicable accounting rules, the Group controls an entity when it is exposed to, or has the rights to, variable returns from its involvement with the entity and has the ability to affect those returns through its power over the entity. In assessing control, the Group takes into consideration potential voting rights, board representation, shareholders' agreements, ability to appoint board of directors and management, de facto control and other related factors. The financial statements of subsidiaries are included in the Consolidated Financial Statements from the date that control commences until the date that control ceases. Losses applicable to the non-controlling interests in a subsidiary are allocated to the non-controlling interests even if doing so causes the non-controlling interests to have a deficit balance.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in Subsidiary Ownership and Loss of Control </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in the Group’s interest in a subsidiary that do not result in a loss of control are accounted for as equity transactions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Where the Group loses control of a subsidiary, the assets and liabilities are derecognized along with any related non-controlling interest (“NCI”). Any interest retained in the former subsidiary is measured at fair value when control is lost. Any resulting gain or loss is recognized as profit or loss in the Consolidated Statement of Comprehensive Income/(Loss).</span></div>
CY2023 ifrs-full Disclosure Of Significant Investments In Subsidiaries Explanatory
DisclosureOfSignificantInvestmentsInSubsidiariesExplanatory
All current subsidiaries are domiciled within the United States and conduct business activities solely within the United States. <div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:43.142%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.990%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.990%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.990%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.990%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.990%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:7.996%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="24" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Voting percentage at December 31, through the holdings in</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Common</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%"> Preferred</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Common</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%"> Preferred</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Common</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%"> Preferred</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Subsidiary operating companies</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio Therapeutics, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega, Inc. (indirectly held through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">77.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">77.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">77.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT, Inc. (formerly Ariya Therapeutics, Inc.)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT 100, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Management, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Health LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Deconsolidated former subsidiary operating companies</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde Health, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2,5</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">40.2</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">40.2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Akili Interactive Labs, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2,6</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14.6</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">26.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna Therapeutics, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2,6</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2, 4</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences Securities Corp. (indirectly held through Vedanta)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2, 4</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vor Biopharma Inc</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">.2,6</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3.9</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Nontrading holding companies</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.4pt;font-weight:400;line-height:120%">Endra Holdings, LLC (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.46pt;font-weight:400;line-height:120%;position:relative;top:-2.94pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.4pt;font-weight:400;line-height:120%">Ensof Holdings, LLC (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.46pt;font-weight:400;line-height:120%;position:relative;top:-2.94pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Securities Corp.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Securities II Corp.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Inactive subsidiaries</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Appeering, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Commense Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99.1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Enlight Biosciences, LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8pt;font-weight:400;line-height:120%">Ensof Biosystems, Inc. (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.2pt;font-weight:400;line-height:120%;position:relative;top:-2.8pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">57.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica, LLC </span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">56.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">56.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">56.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Knode Inc. (indirectly held through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Libra Biosciences, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Mandara Sciences, LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">98.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">98.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">98.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tal Medical, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    On October 30, 2023, Gelesis ceased operations and filed a voluntary petition for relief under the United States bankruptcy code. See Note 6. Investments in Associates for details.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Registered address is Corporation Trust Center, 1209 Orange St., Wilmington, DE 19801, USA.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Registered address is 2711 Centerville Rd., Suite 400, Wilmington, DE 19808, USA.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">4    On March 1, 2023, the Group lost control over Vedanta and Vedanta was deconsolidated from the Group’s financial statements, resulting in only the profits and losses generated by Vedanta through the deconsolidation date being included in the Group’s Consolidated Statement of Comprehensive Income/(Loss). See Notes 5. Investments Held at Fair Value for further details about the accounting for the investments in Vedanta subsequent to deconsolidation.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">5    On May 25, 2022, the Group lost control over Sonde and Sonde was deconsolidated from the Group’s financial statements, resulting in only the profits and losses generated by Sonde through the deconsolidation date being included in the Group’s Consolidated Statement of Comprehensive Income/(Loss). See Notes 5. Investments Held at Fair Value and 6. Investments in Associates for further details about the accounting for the investments in Sonde subsequent to deconsolidation.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">6    See Notes 5. Investments Held at Fair Value and 6. Investments in Associates for additional discussion on the Group's investment held in Akili, Karuna and Vor.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">7    Follica became inactive during 2023.</span></div>
CY2023 ifrs-full Description Of Accounting Policy For Investment In Associates
DescriptionOfAccountingPolicyForInvestmentInAssociates
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Associates </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As used in these financial statements, the term associates are those entities in which the Group has no control but maintains significant influence over the financial and operating policies. Significant influence is presumed to exist when the Group holds between 20 and 50 percent of the voting power of an entity, unless it can be clearly demonstrated that this is not the case. The Group evaluates if it maintains significant influence over associates by assessing if the Group has the power to participate in the financial and operating policy decisions of the associate.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Application of the Equity Method to Associates </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Associates are accounted for using the equity method (equity accounted investees) and are initially recognized at cost, or if recognized upon deconsolidation, they are initially recorded at fair value at the date of deconsolidation. The Consolidated </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Statements include the Group’s share of the total comprehensive income or loss of equity accounted investees, from the date that significant influence commences until the date that significant influence ceases. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">To the extent the Group holds interests in associates that are not providing access to returns underlying ownership interests, the instrument is accounted for in accordance with IFRS 9 as investments held at fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">When the Group’s share of losses exceeds its equity method investment in the investee, losses are applied against long-term interests, which are investments accounted for under IFRS 9. Investments are determined to be long-term interests when they are long-term in nature and in substance they form part of the Group's net investment in that associate. This determination is impacted by many factors, among others, whether settlement by the investee through redemption or repayment is planned or likely in the foreseeable future, whether the investment can be converted and/or is likely to be converted to common stock or other equity instrument and other factors regarding the nature of the investment. Whilst this assessment is dependent on many specific facts and circumstances of each investment, typically conversion features whereby the investment is likely to convert to common stock or other equity instruments would point to the investment being a long-term interest. Similarly, where the investment is not planned or likely to be settled through redemption or repayment in the foreseeable future, this would indicate that the investment is a long-term interest. When the net investment in the associate, which includes the Group’s investments in other long-term interests, is reduced to nil, recognition of further losses is discontinued except to the extent that the Group has incurred legal or constructive obligations or made payments on behalf of an investee.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has adopted the amendments to IAS 28 Investments in Associates that addresses the dual application of IAS 28 and IFRS 9 when equity method losses are applied against long-term interests. The amendments provide the annual sequence in which both standards are to be applied in such a case. The Group has applied the equity method losses to the long-term interests presented as part of Investments held at fair value subsequent to remeasuring such investments to their fair value at balance sheet date.</span></div>
CY2023 ifrs-full Description Of Accounting Policy For Issued Capital Explanatory
DescriptionOfAccountingPolicyForIssuedCapitalExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share Capital </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Ordinary shares are classified as equity. The Group's equity is comprised of share capital, share premium, merger reserve, other reserve, translation reserve, and retained earnings/accumulated deficit.</span></div>
CY2023 ifrs-full Description Of Accounting Policy For Financial Instruments Explanatory
DescriptionOfAccountingPolicyForFinancialInstrumentsExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Instruments </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Classification </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group classifies its financial assets in the following measurement categories:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Those to be measured subsequently at fair value either through other comprehensive income "FVOCI", or through profit or loss "FVTPL", and</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Those to be measured at amortized cost.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The classification depends on the Group’s business model for managing the financial assets and the contractual terms of the cash flows.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For assets measured at fair value, gains and losses are recorded in profit or loss. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Measurement </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">At initial recognition, the Group measures a financial asset at its fair value plus, in the case of a financial asset not at FVTPL, transaction costs that are directly attributable to the acquisition of the financial asset. Transaction costs of financial assets that are carried at FVTPL are expensed.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Impairment </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group assesses on a forward-looking basis the expected credit losses associated with its debt instruments carried at amortized cost. For trade receivables, the Group applies the simplified approach permitted by IFRS 9, which requires expected lifetime losses to be recognized from initial recognition of the receivables.</span></div>
CY2023 ifrs-full Description Of Accounting Policy For Financial Assets Explanatory
DescriptionOfAccountingPolicyForFinancialAssetsExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Financial Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s financial assets consist of cash and cash equivalents, investments in debt securities, trade and other receivables, notes, restricted cash deposits and investments in equity securities. The Group’s financial assets are virtually all classified into the following categories: investments held at fair value, notes, trade and other receivables, short-term investments and cash and cash equivalents. The Group determines the classification of financial assets at initial recognition depending on the purpose for which the financial assets were acquired.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value are investments in equity instruments. Such investments consist of the Group's minority interest holdings where the Group has no significant influence or preferred share investments that are not providing access to returns underlying ownership interests and are categorized as debt instruments that are presented at fair value through profit and loss because the amounts receivable do not represent solely payments of principal and interest. These financial assets are initially measured at fair value and subsequently re-measured at fair value at each reporting date. The Group has elected to record the changes in fair values for the financial assets falling under this category through profit and loss. Please refer to Note 5. Investments Held at Fair Value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in the fair value of financial assets at FVTPL are recognized in other income/(expense) in the Consolidated Statement of Comprehensive Income/(Loss) as applicable. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The notes from an associate, since their contractual terms do not consist solely of cash flow payments of principal and interest on the principal amount outstanding, are initially and subsequently measured at fair value, with changes in fair value recognized through profit and loss.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and cash equivalents consist of demand deposits with banks and other financial institutions and highly liquid instruments with original maturities of three months or less at the date of purchase. Cash and cash equivalents are carried at cost, which approximates their fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term investments consist of short-term US treasury bills that are held to maturity. The contractual terms consist solely of payment of the principal and interest and the Group's business model is to hold the treasury bills to maturity. As such, such short-term investments are recorded at amortized cost. As of balance sheet date, amortized cost approximated the fair value of such short-term investments.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables are non-derivative financial assets with fixed and determinable payments that are not quoted on active markets. These financial assets are carried at the amounts expected to be received less any expected lifetime losses. Such losses are determined taking into account previous experience, credit rating and economic stability of counterparty and economic conditions. When a trade receivable is determined to be uncollectible, it is written off against the available provision. As of balance sheet date, the Group did not record any such expected lifetime losses related to the outstanding trade and other receivable balances. Trade and other receivables are included in current assets, unless maturities are greater than 12 months after the end of the reporting period.</span></div>
CY2023 ifrs-full Description Of Accounting Policy For Financial Liabilities Explanatory
DescriptionOfAccountingPolicyForFinancialLiabilitiesExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Financial Liabilities </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s financial liabilities primarily consist of trade and other payables, and preferred shares. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The majority of the Group’s subsidiaries have preferred shares and certain notes payable with embedded derivatives, which are classified as current liabilities. When the Group has preferred shares and notes with embedded derivatives that qualify for bifurcation, the Group has elected to account for the entire instrument as FVTPL after determining under IFRS 9 that the instrument qualifies to be accounted for under such FVTPL method.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group derecognizes a financial liability when its contractual obligations are discharged, cancelled or expire.</span></div>
CY2023 ifrs-full Description Of Accounting Policy For Recognition Of Revenue
DescriptionOfAccountingPolicyForRecognitionOfRevenue
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">IFRS 15, Revenue from Contracts with Customers </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The standard establishes a five-step principle-based approach for revenue recognition and is based on the concept of recognizing an amount that reflects the consideration for performance obligations only when they are satisfied and the control of goods or services is transferred.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The majority of the Group’s contract revenue is generated from licenses and services, some of which are part of collaboration arrangements. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Management reviewed contracts where the Group received consideration in order to determine whether or not they should be accounted for in accordance with IFRS 15. To date, the Group has entered into transactions that generate revenue and meet the scope of either IFRS 15 or IAS 20 Accounting for Government Grants. Contract revenue is recognized at either a point-in-time or over time, depending on the nature of the performance obligations.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group accounts for agreements that meet the definition of IFRS 15 by applying the following five step model:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Identify the contract(s) with a customer – A contract with a customer exists when (i) the Group enters into an enforceable contract with a customer that defines each party’s rights regarding the goods or services to be transferred and identifies the payment terms related to those goods or services, (ii) the contract has commercial substance and, (iii) the Group determines that collection of substantially all consideration for goods or services that are transferred is probable based on the customer’s intent and ability to pay the promised consideration.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Identify the performance obligations in the contract – Performance obligations promised in a contract are identified based on the goods or services that will be transferred to the customer that are both capable of being distinct, whereby the customer can benefit from the good or service either on its own or together with other resources that are readily available from third parties or from the Group, and are distinct in the context of the contract, whereby the transfer of the goods or services is separately identifiable from other promises in the contract.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Determine the transaction price – The transaction price is determined based on the consideration to which the Group will be entitled in exchange for transferring goods or services to the customer. To the extent the transaction price includes variable consideration, the Group estimates the amount of variable consideration that should be included in the transaction price utilizing either the expected value method or the most likely amount method depending on the nature of the variable consideration. Variable consideration is included in the transaction price if, in the Group’s judgement, it is probable that a significant future reversal of cumulative revenue under the contract will not occur. </span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Allocate the transaction price to the performance obligations in the contract – If the contract contains a single performance obligation, the entire transaction price is allocated to the single performance obligation. Contracts that contain multiple performance obligations require an allocation of the transaction price to each performance obligation based on a relative standalone selling price basis. </span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Recognize revenue when (or as) the Group satisfies a performance obligation – The Group satisfies performance obligations either over time or at a point in time as discussed in further detail below. Revenue is recognized at the time the related performance obligation is satisfied by transferring a promised good or service to a customer.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue generated from services agreements (typically where licenses and related services were combined into one performance obligation) is determined to be recognized over time when it can be determined that the services meet one of the following: (a) the customer simultaneously receives and consumes the benefits provided by the entity’s performance as the entity performs; (b) the entity’s performance creates or enhances an asset that the customer controls as the asset is created or enhanced; or (c) the entity’s performance does not create an asset with an alternative use to the entity and the entity has an enforceable right to payment for performance completed to date.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">It was determined that the Group has contracts that meet criteria (a), since the customer simultaneously receives and consumes the benefits provided by the Group’s performance as the Group performs. Therefore revenue is recognized over time using the input method based on costs incurred to date as compared to total contract costs. The Group believes that in research and development service type agreements using costs incurred to date represents the most faithful depiction of the entity’s performance towards complete satisfaction of a performance obligation.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue from licenses that are not part of a combined performance obligation are recognized at a point in time due to the licenses relating to intellectual property that has significant stand-alone functionality and as such represent a right to use the entity's intellectual property as it exists at the point in time at which the license is granted.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Royalty income received in respect of licensing agreements when the license of intellectual property is the predominant item in the arrangement is recognized as the related third-party sales in the licensee occur.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amounts that are receivable or have been received per contractual terms but have not been recognized as revenue since performance has not yet occurred or has not yet been completed are recorded as deferred revenue. The Group classifies as non-current deferred revenue amounts received for which performance is expected to occur beyond one year or one operating cycle.</span></div>
CY2023 ifrs-full Description Of Accounting Policy For Government Grants
DescriptionOfAccountingPolicyForGovernmentGrants
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Grant Revenue</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group recognizes grants from governmental agencies as grant revenue in the Consolidated Statement of Comprehensive Income/(Loss), gross of the expenditures that were related to obtaining the grant, when there is reasonable assurance that the Group will comply with the conditions within the grant agreement and there is reasonable assurance that payments under the grants will be received. The Group evaluates the conditions of each grant as of each reporting date to ensure that the Group has reasonable assurance of meeting the conditions of each grant arrangement and that it is expected that the grant payment will be received as a result of meeting the necessary conditions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group submits qualifying expenses for reimbursement after the Group has incurred the research and development expense. The Group records an unbilled receivable upon incurring such expenses. In cases in which the grant revenue is received prior to the expenses being incurred or recognized, the amounts received are deferred until the related expense is incurred and/or recognized. Grant revenue is recognized in the Consolidated Statement of Comprehensive Income/(Loss) at the time in which the Group recognizes the related reimbursable expense for which the grant is intended to compensate.</span></div>
CY2023 ifrs-full Description Of Accounting Policy For Functional Currency Explanatory
DescriptionOfAccountingPolicyForFunctionalCurrencyExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Functional and Presentation Currency </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Consolidated Financial Statements are presented in United States dollars (“US dollars”). The functional currency of all members of the Group is the U.S. dollar. The Group's share in foreign exchange differences in associates were reported in other comprehensive income/(loss).</span></div>
CY2023 ifrs-full Description Of Accounting Policy For Foreign Currency Translation Explanatory
DescriptionOfAccountingPolicyForForeignCurrencyTranslationExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Foreign Currency </span></div>Transactions in foreign currencies are translated to the respective functional currencies of Group entities at the foreign exchange rate ruling at the date of the transaction. Monetary assets and liabilities denominated in foreign currencies at the balance sheet date are retranslated to the functional currency at the foreign exchange rate ruling at that date. Foreign exchange differences arising on remeasurement are recognized in the Consolidated Statement of Comprehensive Income/(Loss). Non-monetary assets and liabilities that are measured in terms of historical cost in a foreign currency are translated using the exchange rate at the date of the transaction.
CY2023 ifrs-full Description Of Accounting Policy For Treasury Shares Explanatory
DescriptionOfAccountingPolicyForTreasurySharesExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Treasury Shares</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Treasury shares are recognized at cost and are deducted from shareholders' equity. No gain or loss is recognized in profit and loss for the purchase, sale, re-issue or cancellation of the Group's own equity shares.</span></div>
CY2023 ifrs-full Description Of Accounting Policy For Property Plant And Equipment Explanatory
DescriptionOfAccountingPolicyForPropertyPlantAndEquipmentExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Property and Equipment </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Property and equipment is stated at cost less accumulated depreciation and any accumulated impairment losses. Cost includes expenditures that are directly attributable to the acquisition of the asset. Assets under construction represent leasehold improvements and machinery and equipment to be used in operations or research and development activities. When parts of an item of property and equipment have different useful lives, they are accounted for as separate items (major components) of property and equipment. Depreciation is calculated using the straight-line method over the estimated useful life of the related asset: </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:47.384%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:50.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Laboratory and manufacturing equipment</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2-8 years</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Furniture and fixtures</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7 years</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Computer equipment and software</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1-5 years</span></div></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Leasehold improvements</span></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5-10 years, or the remaining term of the lease, if shorter</span></div></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation methods, useful lives and residual values are reviewed at each balance sheet date.</span></div>
CY2023 ifrs-full Description Of Accounting Policy For Intangible Assets Other Than Goodwill Explanatory
DescriptionOfAccountingPolicyForIntangibleAssetsOtherThanGoodwillExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Intangible Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Intangible assets, which include purchased patents and licenses with finite useful lives, are carried at historical cost less accumulated amortization, if amortization has commenced. Intangible assets with finite lives are amortized from the time they are available for their intended use. Amortization is calculated using the straight-line method to allocate the costs of patents and licenses over their estimated useful lives. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development intangible assets, which are still under development and have accordingly not yet obtained marketing approval, are presented as In-Process Research and Development (IPR&amp;D). The cost of IPR&amp;D represents upfront payments as well as additional contingent payments based on development, regulatory and sales milestones related to certain license agreement where the Group licenses IP from a third party. These milestones are capitalized as the milestone is triggered. See Note 25. Commitments and Contingencies. IPR&amp;D is not amortized since it is not yet available for its intended use, but it is evaluated for potential impairment on an annual basis or more frequently when facts and circumstances warrant.</span></div>
CY2023 ifrs-full Description Of Accounting Policy For Impairment Of Nonfinancial Assets Explanatory
DescriptionOfAccountingPolicyForImpairmentOfNonfinancialAssetsExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment of Non-Financial Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group reviews the carrying amounts of its property and equipment and intangible assets at each reporting date to determine whether there are indicators of impairment. If any such indicators of impairment exist, then an asset’s recoverable amount is estimated. The recoverable amount is the higher of an asset’s fair value less cost of disposal and value in use.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s IPR&amp;D intangible assets are not yet available for their intended use. As such, they are tested for impairment at least annually. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">An impairment loss is recognized when an asset’s carrying amount exceeds its recoverable amount. For the purposes of impairment testing, assets are grouped at the lowest levels for which there are largely independent cash flows. If a non- financial asset instrument is impaired, an impairment loss is recognized in the Consolidated Statement of Comprehensive Income/(Loss).</span></div>Investments in associates are considered impaired if, and only if, objective evidence indicates that one or more events, which occurred after the initial recognition, have had an impact on the future cash flows from the net investment and that impact can be reliably estimated. If an impairment exists, the Group measures an impairment by comparing the carrying value of the net investment in the associate to its recoverable amount and recording any excess as an impairment loss.
CY2023 ifrs-full Description Of Accounting Policy For Employee Benefits Explanatory
DescriptionOfAccountingPolicyForEmployeeBenefitsExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Employee Benefits </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Short-Term Employee Benefits </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term employee benefit obligations are measured on an undiscounted basis and expensed as the related service is provided. A liability is recognized for the amount expected to be paid if the Group has a present legal or constructive obligation due to past service provided by the employee, and the obligation can be estimated reliably.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Defined Contribution Plans </span></div>A defined contribution plan is a post-employment benefit plan under which an entity pays fixed contributions into a separate entity and has no legal or constructive obligation to pay further amounts. Obligations for contributions to defined contribution plans are recognized as an employee benefit expense in the periods during which related services are rendered by employees.
CY2023 ifrs-full Description Of Accounting Policy For Sharebased Payment Transactions Explanatory
DescriptionOfAccountingPolicyForSharebasedPaymentTransactionsExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Share-based Payments </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment arrangements, in which the Group receives goods or services as consideration for its own equity instruments, are accounted for as equity-settled share-based payment transactions (except certain restricted stock units - see below) in accordance with IFRS 2, regardless of how the equity instruments are obtained by the Group. The grant date fair value of employee share-based payment awards is recognized as an expense with a corresponding increase in equity over the requisite service period related to the awards. The amount recognized as an expense is adjusted to reflect the actual number of awards for which the related service and non-market performance conditions are expected to be met, such that the amount ultimately recognized as an expense is based on the number of awards that do meet the related service and non-market performance conditions at the vesting date. For share-based payment awards with market conditions, the grant date fair value is measured to reflect such conditions and there is no true-up for differences between expected and actual outcomes.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain restricted stock units are treated as liability settled awards starting in 2021. Such awards are remeasured at every reporting date until settlement date and are recognized as compensation expense over the requisite service period. Differences in remeasurement are recognized in profit and loss. The cumulative cost that will ultimately be recognized in respect of these awards will equal to the amount at settlement. </span></div>The fair value of the awards is measured using option pricing models and other appropriate models, which take into account the terms and conditions of the awards granted.
CY2023 ifrs-full Description Of Accounting Policy For Research And Development Expense Explanatory
DescriptionOfAccountingPolicyForResearchAndDevelopmentExpenseExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Development Costs </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expenditures on research activities are recognized as incurred in the Consolidated Statement of Comprehensive Income/(Loss). In accordance with IAS 38, development costs are capitalized only if the expenditure can be measured reliably, the product or process is technically and commercially feasible, future economic benefits are probable, the Group can demonstrate its ability to use or sell the intangible asset, the Group intends to and has sufficient resources to complete development and to use or sell the asset, and it is able to measure reliably the expenditure attributable to the intangible asset during its development. The point at which technical feasibility is determined to have been reached is, generally, when regulatory approval has been received where applicable. Management determines that commercial viability has been reached when a clear market and pricing point have been identified, which may coincide with achieving meaningful recurring sales. Otherwise, the development expenditure is recognized </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">as incurred in the Consolidated Statement of Comprehensive Income/(Loss). As of balance sheet date, the Group has not capitalized any development costs.</span></div>
CY2023 ifrs-full Description Of Accounting Policy For Provisions Explanatory
DescriptionOfAccountingPolicyForProvisionsExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Provisions </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">A provision is recognized in the Consolidated Statement of Financial Position when the Group has a present legal or constructive obligation due to a past event that can be reliably measured, and it is probable that an outflow of economic benefits will be required to settle the obligation. Provisions are determined by discounting the expected future cash flows at a pre-tax rate that reflects risks specific to the liability.</span></div>
CY2023 ifrs-full Description Of Accounting Policy For Leases Explanatory
DescriptionOfAccountingPolicyForLeasesExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Leases</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group leases real estate for use in operations. These leases have lease terms of approximately 10 years. The Group includes options that are reasonably certain to be exercised as part of the determination of the lease term. The group determines if an arrangement is a lease at inception of the contract in accordance with guidance detailed in IFRS 16. Right-of-use (ROU) assets represent the Group’s right to use an underlying asset for the lease term and lease liabilities represent the Group's obligation to make lease payments arising from the lease. Operating lease ROU assets and lease liabilities are recognized at commencement date based on the present value of the lease payments over the lease term. As most of the Group's leases do not provide an implicit rate, the Group used its estimated incremental borrowing rate, based on information available at commencement date, in determining the present value of future payments. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s leases are virtually all leases of real estate.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has elected to account for lease payments as an expense on a straight-line basis over the life of the lease for: </span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Leases with a term of 12 months or less and containing no purchase options; and </span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Leases where the underlying asset has a value of less than $5,000. </span></div>The right-of-use asset is depreciated on a straight-line basis and the lease liability gives rise to an interest charge.
CY2023 ptv Lease Term Of Contract
LeaseTermOfContract
P10Y
CY2023 ifrs-full Description Of Accounting Policy For Finance Income And Costs Explanatory
DescriptionOfAccountingPolicyForFinanceIncomeAndCostsExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance Income and Finance Costs </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income consists of interest income on funds invested in money market funds and U.S. treasuries. Finance income is recognized as it is earned. Finance costs consist mainly of loan, notes and lease liability interest expenses, interest expense due to accretion of and adjustment to sale of future royalties liability as well as the changes in the fair value of financial liabilities carried at FVTPL (such changes can consist of finance income when the fair value of such financial liabilities decreases).</span></div>
CY2023 ifrs-full Description Of Accounting Policy For Income Tax Explanatory
DescriptionOfAccountingPolicyForIncomeTaxExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax on the profit or loss for the year comprises current and deferred income tax. In accordance with IAS 12, tax is recognized in the Consolidated Statement of Comprehensive Income/(Loss) except to the extent that it relates to items recognized directly in equity.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current income tax is the expected tax payable or receivable on the taxable income or loss for the year, using tax rates enacted or substantially enacted at the reporting date, and any adjustment to tax payable in respect of previous years.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax is recognized due to temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for taxation purposes. Deferred tax assets are recognized for unused tax losses, unused tax credits and deductible temporary differences to the extent that it is probable that future taxable profits will be available against which they can be used. Deferred tax assets with respect to investments in associates are recognized only to the extent that it is probable the temporary difference will reverse in the foreseeable future and taxable profit will be available against which the temporary difference can be utilized. Deferred tax assets are reviewed at each reporting date and are reduced to the extent that it is no longer probable that the related tax benefit will be realized.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax is measured at the tax rates that are expected to be applied to temporary differences when they reverse, using tax rates enacted or substantively enacted at the reporting date.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred income tax assets and liabilities are offset when there is a legally enforceable right to offset current tax assets against current tax liabilities and when the deferred income tax assets and liabilities relate to income taxes levied by the same taxation authority on either the same taxable entity or different taxable entities where there is an intention to settle the balances on a net basis.</span></div>
CY2023 ifrs-full Description Of Accounting Policy For Fair Value Measurement Explanatory
DescriptionOfAccountingPolicyForFairValueMeasurementExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair Value Measurements </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s accounting policies require that certain financial assets and certain financial liabilities be measured at their fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group uses valuation techniques that are appropriate in the circumstances and for which sufficient data are available to measure fair value, maximizing the use of relevant observable inputs and minimizing the use of unobservable inputs. Fair values are categorized into different levels in a fair value hierarchy based on the inputs used in the valuation techniques as follows:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 1: quoted prices (unadjusted) in active markets for identical assets or liabilities.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 2: inputs other than quoted prices included in Level 1 that are observable for the asset or liability, either directly (i.e. as prices) or indirectly (i.e. derived from prices).</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 3: inputs for the asset or liability that are not based on observable market data (unobservable inputs).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group recognizes transfers between levels of the fair value hierarchy at the end of the reporting period during which the change has occurred.</span></div>The carrying amount of cash and cash equivalents, accounts receivable, restricted cash, deposits, accounts payable, accrued expenses and other current liabilities in the Group’s Consolidated Statement of Financial Position approximates their fair value because of the short maturities of these instruments.
CY2023 ifrs-full Description Of Accounting Policy For Segment Reporting Explanatory
DescriptionOfAccountingPolicyForSegmentReportingExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating Segments </span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating segments are reported in a manner that is consistent with the internal reporting provided to the chief operating decision maker (“CODM”). The CODM reviews discrete financial information for the operating segments in order to assess their </span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">performance and is responsible for making decisions about resources allocated to the segments. The CODM has been identified as the Group’s Board of Directors.</span></div>
CY2023 ifrs-full Disclosure Of Changes In Accounting Policies Explanatory
DisclosureOfChangesInAccountingPoliciesExplanatory
New Standards and Interpretations<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has applied the following amendments for the first time for its annual reporting period commencing January 1, 2023:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">IFRS 17 </span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Insurance Contracts</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%;padding-left:7.09pt">Definition of Accounting Estimates</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> (Amendments to IAS 8)</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%;padding-left:7.09pt">Deferred Tax related to Assets and Liabilities Arising from a Single Transaction</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> (Amendments to IAS 12)</span></div><div style="margin-bottom:5pt;margin-top:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The amendments listed above did not have any impact on the amounts recognized in prior and current periods and are not expected to significantly affect the future periods.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain new accounting standards, amendments to accounting standards and interpretations have been published that are not mandatory for December 31, 2023 reporting periods and have not been early adopted by the Group. These standards, amendments or interpretations are not expected to have a material impact on the Group in the current or future reporting periods and on foreseeable future transactions.</span></div>
CY2023 ifrs-full Description Of Expected Impact Of Initial Application Of New Standards Or Interpretations
DescriptionOfExpectedImpactOfInitialApplicationOfNewStandardsOrInterpretations
New Standards and Interpretations<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has applied the following amendments for the first time for its annual reporting period commencing January 1, 2023:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">IFRS 17 </span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Insurance Contracts</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%;padding-left:7.09pt">Definition of Accounting Estimates</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> (Amendments to IAS 8)</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%;padding-left:7.09pt">Deferred Tax related to Assets and Liabilities Arising from a Single Transaction</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> (Amendments to IAS 12)</span></div><div style="margin-bottom:5pt;margin-top:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The amendments listed above did not have any impact on the amounts recognized in prior and current periods and are not expected to significantly affect the future periods.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain new accounting standards, amendments to accounting standards and interpretations have been published that are not mandatory for December 31, 2023 reporting periods and have not been early adopted by the Group. These standards, amendments or interpretations are not expected to have a material impact on the Group in the current or future reporting periods and on foreseeable future transactions.</span></div>
CY2023 ifrs-full Disclosure Of Revenue Explanatory
DisclosureOfRevenueExplanatory
Revenue <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue recorded in the Consolidated Statement of Comprehensive Income/(Loss) consists of the following:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,090 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,979 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,580</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,528 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,409 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total revenue</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,330</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,618 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,388 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">All amounts recorded in contract revenue were generated in the United States. </span></div><div style="margin-bottom:5pt;margin-top:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For the years ended December 31, 2023, 2022 and 2021, contract revenue includes royalties received from an associate in the amounts of zero, $509 and $231, respectively.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Substantially all of the Group’s contracts related to contract revenue for the years ended December 31, 2023, 2022 and 2021 were determined to have a single performance obligation which consists of a combined deliverable of license of intellectual property and research and development services. Therefore, for such contracts, revenue is recognized over time based on the input method which the Group believes is a faithful depiction of the transfer of goods and services. Progress is measured based on costs incurred to date as compared to total projected costs. Payments for such contracts are primarily made up-front on a periodic basis.</span></div><div style="margin-bottom:5pt;margin-top:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2021, the Group received a $6,500 payment from Imbrium Therapeutics, Inc. following the exercise of the option to acquire an exclusive license for the Initial Product Candidate, as defined in the agreement. Since the license transferred was a right to use license, revenue from the option exercise was recognized at a point in time upon transfer of the license, which occurred during the year ended December 31, 2021.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disaggregated Revenue</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group disaggregates contract revenue in a manner that depicts how the nature, amount, timing, and uncertainty of revenue and cash flows are affected by economic factors. The Group disaggregates revenue based on contract revenue or grant revenue, and further disaggregates contract revenue based on the transfer of control of the underlying performance obligations.</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Timing of contract revenue recognition</span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transferred at a point in time – Licensing Income</span></div></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">527 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,809 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transferred over time</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,563 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,171 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,090 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,979 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:2pt;padding-left:13.5pt;text-indent:-13.5pt"><span><br/></span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Customers over 10% of revenue</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer A</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,500 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,500 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer B</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,250 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer C</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">509 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,009 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,750 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div>Accounts receivables represent rights to consideration in exchange for products or services that have been transferred by the Group, when payment is unconditional and only the passage of time is required before payment is due. Accounts receivables do not bear interest and are recorded at the invoiced amount. Accounts receivables are included within trade and other receivables on the Consolidated Statement of Financial Position. The accounts receivables related to contract revenue were $555 and $606 as of December 31, 2023 and 2022, respectively.
CY2023 ifrs-full Disclosure Of Revenue From Contracts With Customers Explanatory
DisclosureOfRevenueFromContractsWithCustomersExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue recorded in the Consolidated Statement of Comprehensive Income/(Loss) consists of the following:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,090 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,979 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,580</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,528 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,409 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total revenue</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,330</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,618 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,388 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div>
CY2023 ifrs-full Revenue From Contracts With Customers
RevenueFromContractsWithCustomers
750000 usd
CY2022 ifrs-full Revenue From Contracts With Customers
RevenueFromContractsWithCustomers
2090000 usd
CY2021 ifrs-full Revenue From Contracts With Customers
RevenueFromContractsWithCustomers
9979000 usd
CY2023 ifrs-full Revenue From Government Grants
RevenueFromGovernmentGrants
2580000 usd
CY2022 ifrs-full Revenue From Government Grants
RevenueFromGovernmentGrants
13528000 usd
CY2021 ifrs-full Revenue From Government Grants
RevenueFromGovernmentGrants
7409000 usd
CY2023 ifrs-full Revenue
Revenue
3330000 usd
CY2022 ifrs-full Revenue
Revenue
15618000 usd
CY2021 ifrs-full Revenue
Revenue
17388000 usd
CY2023 ifrs-full Disclosure Of Disaggregation Of Revenue From Contracts With Customers Explanatory
DisclosureOfDisaggregationOfRevenueFromContractsWithCustomersExplanatory
<div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Timing of contract revenue recognition</span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transferred at a point in time – Licensing Income</span></div></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">527 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,809 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transferred over time</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,563 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,171 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,090 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,979 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:2pt;padding-left:13.5pt;text-indent:-13.5pt"><span><br/></span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Customers over 10% of revenue</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer A</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,500 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,500 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer B</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,250 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer C</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">509 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,009 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,750 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div>
CY2023 ifrs-full Revenue From Contracts With Customers
RevenueFromContractsWithCustomers
750000 usd
CY2022 ifrs-full Revenue From Contracts With Customers
RevenueFromContractsWithCustomers
2090000 usd
CY2021 ifrs-full Revenue From Contracts With Customers
RevenueFromContractsWithCustomers
9979000 usd
CY2023Q4 ifrs-full Receivables From Contracts With Customers
ReceivablesFromContractsWithCustomers
555000 usd
CY2022Q4 ifrs-full Receivables From Contracts With Customers
ReceivablesFromContractsWithCustomers
606000 usd
CY2023 ifrs-full Disclosure Of Entitys Reportable Segments Explanatory
DisclosureOfEntitysReportableSegmentsExplanatory
Segment Information<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basis for Segmentation </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Directors are the Group’s chief operating decision-makers. The Group’s operating segments are determined based on the financial information provided to the Board of Directors periodically for the purposes of allocating resources and assessing performance. During the second half of 2023, the Group changed the financial information that was regularly reviewed by the Board of Directors to allocate resources and assess performance. The Group has determined each of its Wholly-Owned Programs represents an operating segment and the Group has aggregated each of these operating segments into one reportable segment, the Wholly-Owned Programs segment, given the high level of operational and financial similarities across its Wholly-Owned Programs. Each of the Group’s Controlled Founded Entities represents an operating segment. The Group aggregates each Controlled Founded Entity operating segment into one reportable segment, the Controlled Founded Entities segment. For the Group’s entities that do not meet the definition of an operating segment, the Group presents this information in the Parent &amp; Other column in its segment footnote to reconcile the information in this footnote to the Consolidated Financial Statements. Substantially all of the Group’s revenue and profit generating activities are generated within the United States and, accordingly, no geographical disclosures are provided. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has retroactively recast its fiscal year 2022 and 2021 results on the new basis for comparability.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Following is the description of the Group's reportable segments:</span></div><div style="margin-top:5pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Wholly-Owned Programs</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Wholly-Owned Programs segment is advancing Wholly-Owned Programs which are focused on treatments for patients with devastating diseases. The Wholly-Owned Programs segment is comprised of the technologies that are wholly-owned and will be advanced through with either the Group's funding or non-dilutive sources of financing. The operational management of the Wholly-Owned Programs segment is conducted by the PureTech Health team, which is responsible for the strategy, business development, and research and development. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Controlled Founded Entities</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Controlled Founded Entities segment is comprised of the Group’s consolidated operational subsidiaries as of December 31, 2023 that either have, or have plans to hire, independent management teams and currently have already raised third-party dilutive capital. These subsidiaries have active research and development programs and either have entered into or plan to seek an equity or debt investment partner, who will provide additional industry knowledge and access to networks, as well as additional funding to continue the pursued growth of the entity. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s entities that were determined not to meet the definition of an operating segment are included in the Parent Company and Other column to reconcile the information in this footnote to the financial statements. This column captures activities not directly attributable to the Group's operating segments and includes the activities of the Parent, corporate support functions and certain research and development support functions that are not directly attributable to a strategic business segment as well as the elimination of intercompany transactions. This column also captures the operating results for the deconsolidated entities through the date of deconsolidation (e.g. Vedanta in 2023 and Sonde in 2022) and accounting for the Group's holdings in Founded Entities for which control has been lost, which primarily represents: the activity associated with deconsolidating an entity when the Group no longer controls the entity (e.g. Vedanta in 2023 and Sonde in 2022), the gain or loss on the Group's investments accounted for at fair value (e.g. the Group's ownership stakes in Karuna, Vor and Akili) and the Group's net income or loss of associates accounted for using the equity method. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(The term "Founded Entities" refers to entities which the Company incorporated and announced the incorporation as a Founded Entity externally. It includes certain of the Company’s wholly-owned subsidiaries which have been announced by the Company as Founded Entities, Controlled Founded Entities and deconsolidated Founded Entities.)</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In January 2024, the Group launched two new Founded Entities to advance certain programs from the Wholly-Owned Programs segment. Refer to Note 28. Subsequent Events for detail. The financial results of these programs were included in the Wholly-Owned Programs segment as of December 31, 2023 and 2022 and for the three years ended December 31, 2023, 2022 and 2021, respectively. Upon raising dilutive third-party financing, the financial results of these two entities will be included in the Controlled Founded Entities segment to the extent that the Group maintains control over these entities.</span></div><div style="margin-bottom:5pt;margin-top:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s Board of Directors reviews segment performance and allocates resources based upon revenue and operating loss as well as the funds available for each segment. The Board of Directors do not review any other information for purposes of assessing segment performance or allocating resources. </span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:52.839%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="12" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">For the year ended December 31, 2023</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Wholly-Owned Programs</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Controlled Founded Entities</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Parent Company &amp; </span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Other</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Consolidated</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">853</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,727</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,580</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">853</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,727</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,330</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(14,020)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(562)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(38,713)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(53,295)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(89,495)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(672)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(6,068)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(96,235)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total operating expense</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(103,516)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,233)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(44,781)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(149,530)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Operating income/(loss)</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(102,662)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(483)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(43,054)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(146,199)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/expenses not allocated to segments</span></div></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation of subsidiary</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">61,787</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investment held at fair value</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">77,945</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Realized loss on sale of investments</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(122)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investment in notes from associates</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(27,630)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(908)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total other income/(expense)</span></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">111,072</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,078</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associates accounted for using the equity method</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(6,055)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) before taxes</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(36,103)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:0 1pt"></td><td colspan="12" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">As of December 31, 2023</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Available Funds</span></div></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and cash equivalents</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,140</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">675</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">188,266</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">191,081</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term Investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">136,062</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">136,062</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated cash, cash equivalents and short-term investments</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,140</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">675</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">324,328</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">327,143</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:1pt;padding-left:11.34pt;text-indent:-11.34pt"><span><br/></span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:52.839%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="12" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31, 2022</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wholly-Owned Programs<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Parent</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Company &amp;</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Other</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Consolidated</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,500 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">590 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,090 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,826 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,702 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,528 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,826 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,500 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,292 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,618 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,301)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(419)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(52,272)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(60,991)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(116,054)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,051)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(35,328)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(152,433)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total Operating expenses</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(124,355)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,470)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(87,600)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(213,425)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating income/(loss)</span></div></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(121,529)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(76,308)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(197,807)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/expenses not allocated to segments</span></div></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,251 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investment held at fair value</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(32,060)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Realized loss on sale of investments</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(29,303)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,131 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total other income/(expense)</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(25,981)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">138,924 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associate accounted for using the equity method</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(27,749)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on dilution of ownership interest in associate</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28,220 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment of investment in associates</span></div></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,390)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) before taxes </span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(92,783)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:0 1pt"></td><td colspan="12" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31, 2022</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Available Funds</span></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and cash equivalents</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,306 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">823 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">141,737 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">149,866 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term Investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">200,229 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">200,229 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated cash, cash equivalents and short-term investments</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,306 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">823 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">341,966 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">350,095 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:52.839%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="12" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31, 2021</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wholly-Owned Programs<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Parent</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Company &amp;</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Other</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Consolidated</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.5pt solid #6d6d6d;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="border-top:0.5pt solid #6d6d6d;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,129 </span></td><td style="border-top:0.5pt solid #6d6d6d;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #6d6d6d;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,500 </span></td><td style="border-top:0.5pt solid #6d6d6d;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.5pt solid #6d6d6d;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">350 </span></td><td style="border-top:0.5pt solid #6d6d6d;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #6d6d6d;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,979 </span></td><td style="border-top:0.5pt solid #6d6d6d;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,253 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,156 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,409 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,382 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,500 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,506 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,388 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,673)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(365)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(48,161)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(57,199)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(65,444)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(918)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(44,108)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(110,471)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total operating expense</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(74,118)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,284)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(92,269)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(167,671)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating income/(loss)</span></div></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(64,736)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">216 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(85,763)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(150,282)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/expenses not allocated to segments</span></div></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investment held at fair value</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">179,316 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Realized loss on sale of investments</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(20,925)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,592 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">159,983 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,050 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associate accounted for using the equity method</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(73,703)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) before taxes</span></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(58,953)</span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr></table></div>
CY2023 ifrs-full Disclosure Of Operating Segments Explanatory
DisclosureOfOperatingSegmentsExplanatory
<div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:52.839%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="12" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">For the year ended December 31, 2023</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Wholly-Owned Programs</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Controlled Founded Entities</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Parent Company &amp; </span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Other</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Consolidated</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">853</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,727</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,580</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">853</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,727</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,330</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(14,020)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(562)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(38,713)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(53,295)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(89,495)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(672)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(6,068)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(96,235)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total operating expense</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(103,516)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,233)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(44,781)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(149,530)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Operating income/(loss)</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(102,662)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(483)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(43,054)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(146,199)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/expenses not allocated to segments</span></div></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation of subsidiary</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">61,787</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investment held at fair value</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">77,945</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Realized loss on sale of investments</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(122)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investment in notes from associates</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(27,630)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(908)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total other income/(expense)</span></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">111,072</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,078</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associates accounted for using the equity method</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(6,055)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) before taxes</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(36,103)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:0 1pt"></td><td colspan="12" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">As of December 31, 2023</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Available Funds</span></div></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and cash equivalents</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,140</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">675</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">188,266</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">191,081</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term Investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">136,062</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">136,062</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated cash, cash equivalents and short-term investments</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,140</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">675</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">324,328</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">327,143</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:1pt;padding-left:11.34pt;text-indent:-11.34pt"><span><br/></span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:52.839%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="12" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31, 2022</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wholly-Owned Programs<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Parent</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Company &amp;</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Other</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Consolidated</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,500 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">590 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,090 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,826 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,702 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,528 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,826 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,500 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,292 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,618 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,301)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(419)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(52,272)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(60,991)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(116,054)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,051)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(35,328)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(152,433)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total Operating expenses</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(124,355)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,470)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(87,600)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(213,425)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating income/(loss)</span></div></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(121,529)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(76,308)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(197,807)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/expenses not allocated to segments</span></div></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,251 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investment held at fair value</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(32,060)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Realized loss on sale of investments</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(29,303)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,131 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total other income/(expense)</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(25,981)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">138,924 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associate accounted for using the equity method</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(27,749)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on dilution of ownership interest in associate</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28,220 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment of investment in associates</span></div></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,390)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) before taxes </span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(92,783)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:0 1pt"></td><td colspan="12" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31, 2022</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Available Funds</span></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and cash equivalents</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,306 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">823 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">141,737 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">149,866 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term Investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">200,229 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">200,229 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated cash, cash equivalents and short-term investments</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,306 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">823 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">341,966 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">350,095 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:52.839%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="12" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31, 2021</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wholly-Owned Programs<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Parent</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Company &amp;</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Other</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Consolidated</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.5pt solid #6d6d6d;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="border-top:0.5pt solid #6d6d6d;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,129 </span></td><td style="border-top:0.5pt solid #6d6d6d;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #6d6d6d;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,500 </span></td><td style="border-top:0.5pt solid #6d6d6d;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.5pt solid #6d6d6d;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">350 </span></td><td style="border-top:0.5pt solid #6d6d6d;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #6d6d6d;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,979 </span></td><td style="border-top:0.5pt solid #6d6d6d;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,253 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,156 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,409 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,382 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,500 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,506 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,388 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,673)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(365)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(48,161)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(57,199)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(65,444)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(918)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(44,108)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(110,471)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total operating expense</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(74,118)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,284)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(92,269)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(167,671)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating income/(loss)</span></div></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(64,736)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">216 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(85,763)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(150,282)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/expenses not allocated to segments</span></div></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investment held at fair value</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">179,316 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Realized loss on sale of investments</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(20,925)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,592 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">159,983 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,050 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associate accounted for using the equity method</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(73,703)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) before taxes</span></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(58,953)</span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr></table></div>
CY2021Q4 ifrs-full Noncurrent Financial Assets At Fair Value Through Profit Or Loss
NoncurrentFinancialAssetsAtFairValueThroughProfitOrLoss
493888000 usd
CY2022 ifrs-full Losses On Disposals Of Investments
LossesOnDisposalsOfInvestments
29303000 usd
CY2022 ifrs-full Increase Decrease In Fair Value Measurement Assets
IncreaseDecreaseInFairValueMeasurementAssets
-32060000 usd
CY2022Q4 ifrs-full Noncurrent Financial Assets At Fair Value Through Profit Or Loss
NoncurrentFinancialAssetsAtFairValueThroughProfitOrLoss
251892000 usd
CY2023 ifrs-full Losses On Disposals Of Investments
LossesOnDisposalsOfInvestments
265000 usd
CY2023 ifrs-full Gains Losses Recognised In Profit Or Loss Excluding Exchange Differences Fair Value Measurement Assets
GainsLossesRecognisedInProfitOrLossExcludingExchangeDifferencesFairValueMeasurementAssets
77945000 usd
CY2023Q4 ifrs-full Noncurrent Financial Assets At Fair Value Through Profit Or Loss
NoncurrentFinancialAssetsAtFairValueThroughProfitOrLoss
317841000 usd
CY2022 ifrs-full Gains Losses Recognised When Control In Subsidiary Is Lost
GainsLossesRecognisedWhenControlInSubsidiaryIsLost
27251000 usd
CY2023 ifrs-full Disclosure Of Significant Investments In Associates Explanatory
DisclosureOfSignificantInvestmentsInAssociatesExplanatory
Investments in Associates<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis was founded by the Group and raised funding through preferred shares financings as well as issuances of warrants and loans. As of July 1, 2019, Gelesis was deconsolidated from the Group’s financial statements. Upon deconsolidation, the preferred shares and warrants held by the Group fell under the guidance of IFRS 9 </span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Financial Instruments</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> and were treated as financial assets held at fair value and the investment in common shares of Gelesis was subject to IAS 28 </span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Investment in Associates</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> as the Group had significant influence over Gelesis. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">2021</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Due to the Group's share in the losses of Gelesis, in 2020, the Group's investment in Gelesis accounted for under the equity method was reduced to zero. Since the Group had investments in Gelesis warrants and preferred shares that were deemed to be long-term interests, the Group continued recognizing its share in Gelesis losses while applying such losses to its preferred share and warrant investment in Gelesis accounted for as an investment held at fair value. In 2021, total investment in Gelesis, including the long-term interests, was reduced to zero. Since the Group did not incur legal or constructive obligations or made payments on behalf of Gelesis, the Group discontinued recognizing equity method losses in 2021. As of December 31, 2021, unrecognized equity method losses amounted to $38,101, which included $709 of unrecognized other comprehensive loss.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During 2021, due to exercise of stock options into common shares in Gelesis, the Group's equity interest in Gelesis was reduced from 47.9 percent at December 31, 2020 to 42.0 percent as of December 31, 2021. The gain resulting from the issuance of shares to third parties and the resulting reduction in the Group's share in the accumulated deficit of Gelesis under the equity method was fully offset by the unrecognized equity method losses.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Backstop agreement – 2022 and 2021</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On December 30, 2021, the Group signed a Backstop agreement with Capstar and had committed to acquire Capstar class A common shares at $10 per share immediately prior to the closing of the business combination between Gelesis and Capstar, in case, the Available Funds, as defined in the agreement, were less than $15,000. According to the Backstop agreement, if the Group had to acquire any shares under the agreement, the Group would receive an additional 1,322,500 class A common shares of Capstar at no additional consideration.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group determined that such agreement meets the definition of a derivative under IFRS 9 and as such should be recorded at fair value with changes in fair value recorded through profit and loss. The derivative was initially recorded at fair value adjusted to defer the day 1 gain equal to the difference between the fair value of $11,200 and transaction price of zero on the effective date of the Backstop agreement and as such was initially recorded at zero. The deferred gain was amortized over the period from the effective date until settlement date, January 13, 2022. During the years ended December 31, 2022 and 2021, the Group recognized income of $10,400 and $800, respectively, for the amortization of the deferred gain. During the year ended December 31, 2022, the Group recognized a loss of $2,776 in respect of the decrease in the fair value of the derivative until the settlement date, resulting in a net gain of $7,624 recorded during the year ended December 31, 2022 in respect of the Backstop agreement. The gain was included in other Income/(expense) in the Consolidated Statement of Comprehensive Income/(Loss). The fair value of the derivative on the settlement date in the amount of $8,424 represents an additional investment in Gelesis as part of the SPAC transaction described below.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On January 13, 2022, as part of the conclusion of the aforementioned Backstop agreement, the Group acquired 496,145 class A common shares of Capstar for $4,961 and received an additional 1,322,500 class A common shares of Capstar for no additional consideration.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">2022</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Share exchange – Capstar</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On January 13, 2022, Gelesis completed its business combination with Capstar. As part of the business combination, all shares in Gelesis, common and preferred, including the shares held by the Group, were exchanged for common shares of the merged entity and unvested common shares that will vest upon the stock price of the new combined entity reaching certain target prices (the "Gelesis Earn-out Shares"). In addition, the Group invested $15,000 in the class A common shares of Capstar as part of the PIPE transaction that took place immediately prior to the closing of the business combination and an additional $4,961, as part of the Backstop agreement described above. Pursuant to the business combination, Gelesis became a wholly-owned subsidiary of Capstar and Capstar changed its name to Gelesis Holdings, Inc., which began trading on the New York Stock Exchange under the ticker symbol "GLS" on January 14, 2022. Following the closing of the business combination, the PIPE transaction, the settlement of the aforementioned Backstop agreement with Capstar, and the exchange of all preferred shares in Gelesis to common shares in the new combined entity, the Group holds 16,727,582 common shares of Gelesis Holdings Inc., which was equal to approximately 23.2% of Gelesis Holdings Inc's outstanding common shares at the time of the exchange. Due to the Group's significant equity holding and voting interest in Gelesis, the Group continued to maintain significant influence in Gelesis and as such continued to account for its Gelesis equity investment under the equity method.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis was deemed to be the acquirer in Gelesis Holdings Inc. and the financial assets and financial liabilities in Capstar were deemed to be acquired by Gelesis in consideration for the shares held by Capstar legacy shareholders. As such, the Group did not revalue the retained investment in Gelesis but rather treated the exchange as a dilution of its equity interest in Gelesis from 42.0 percent as of December 31, 2021 to 22.8 percent as of January 13, 2022 (including warrants that provide its holders access to returns associated with equity holders). After considering the aforementioned additional investments, the exchange of the preferred stock, previously accounted for as an investment held at fair value, to common stock (and representing an additional equity investment in Gelesis), the earn-out shares received in Gelesis (see Note 5. Investments Held at Fair Value) and the offset of previously unrecognized equity method losses, the net gain recorded on the dilution of interest amounted to $28,255.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Impairment</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Following Gelesis’ decline in its market price in 2022 and its lack of liquidity, the Group recorded an impairment loss of $8,390 as of December 31, 2022 in respect of its investment in Gelesis. The recoverable amount of the investment in Gelesis was $4,910 as of December 31, 2022, which was determined based on fair value less costs to sell (which were estimated to be insignificant). Fair value was determined based on level 1 of the fair value hierarchy as Gelesis shares were traded on an active market as of December 31, 2022.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The impairment loss was presented separately in the Consolidated Statement of Comprehensive Income/(loss) for the year ended December 31, 2022 in the line item impairment of investment in associates.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">2023</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2023, the Group entered into agreements with Gelesis to purchase senior secured convertible promissory notes and warrants for shares of Gelesis common stock (see Note 7. Investment in Notes from Associates). The warrants to purchase shares of Gelesis common stock represented potential voting rights to the Group and it is therefore </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">necessary to consider whether they were substantive. If these potential voting rights were substantive and the Group had the practical ability to exercise the rights and take control of greater than 50% of Gelesis common stock, the Group would be required to consolidate Gelesis under the accounting standards.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In February 2023, the Group obtained warrants to purchase 23,688,047 shares of Gelesis common stock (the “February Warrants”) at an exercise price of $0.2744 per share. The exercise of the February Warrants was subject to the approval of the Gelesis stockholders until May 1, 2023. On May 1, 2023, stockholder approval was no longer required for the Group to exercise the February Warrants. The potential voting rights associated with the February Warrants were not substantive as the exercise price of the February Warrants was at a significant premium to the fair value of the Gelesis common stock.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In May 2023, the Group obtained warrants to purchase 235,441,495 shares of Gelesis common stock (the “May Warrants”). The May Warrants were exercisable at the option of the Group and had an exercise price of either $0.0182 or $0.0142. The May Warrants were substantive as the Group would have benefited from exercising such warrants since their exercise price was at the money or at an insignificant premium over the fair value of the Gelesis common stock. However, that benefit from exercising the May Warrants only existed for a short period of time because in June 2023, the potential voting rights associated with the May Warrants were impacted by the terms and conditions of the Merger Agreement as described below and were no longer substantive. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In October 2023, the Group terminated the Merger Agreement with Gelesis and the potential voting rights associated with the May Warrants were not substantive. Also, in October 2023, Gelesis ceased operations and filed a voluntary petition for relief under the provisions of Chapter 7 of Title 11 of the United States Bankruptcy Code. A Chapter 7 trustee has been appointed by the Bankruptcy Court who has control over the assets and liabilities of Gelesis, effectively eliminating the authority and powers of the Board of Directors of Gelesis and its executive officers to act on behalf of Gelesis. The assets of Gelesis will be liquidated and Gelesis no longer has any officers or employees. The Group ceased accounting for Gelesis as an equity method investment as it no longer had significant influence in Gelesis. During the year ended December 31, 2023, the Group recorded $4,910 as its share in the losses of Gelesis and the Group’s balance in this equity method investment was zero as of December 31, 2023. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Merger Agreement </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On June 12, 2023, PureTech Health LLC and Caviar Merger Sub LLC, a Delaware limited liability company and a wholly-owned subsidiary of PureTech (“Merger Sub”), entered into an agreement (the "Merger Agreement"), pursuant to which Gelesis would merge with and into Merger Sub, with Merger Sub continuing as the surviving company ( the “Merger”). If the Merger had been completed, PureTech would have acquired all issued and outstanding shares of common stock of Gelesis not otherwise held by PureTech, and Gelesis would have become an indirect wholly-owned subsidiary of PureTech. On October 12, 2023, the Group terminated the Merger Agreement. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On May 25, 2022, Sonde completed a Series B preferred share financing. As a result of the aforementioned financing, the Group's voting interest was reduced below 50% and the Group lost its control over Sonde and as such ceased to consolidate Sonde on the date the round of financing was completed. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Following deconsolidation, the Group has significant influence in Sonde through its voting interest in Sonde and its remaining representation on Sonde's Board of Directors. The Group's voting interest at date of deconsolidation and as of December 31, 2022 was 48.2% and 40.17%, respectively. The Group holds Preferred A-1, A-2 and B shares. The Preferred A-1 shares, in substance, have the same terms as common stock and as such provide their shareholders with access to returns associated with a residual equity ownership in Sonde. Consequently, the investment in Preferred A-1 shares is accounted for under the equity method. The Preferred A-2 and B shares, however, do not provide their shareholders with access to returns associated with a residual equity interest and as such are accounted for under IFRS 9, as investments held at fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the Preferred A-1 shares on the date of deconsolidation amounted to $7,716, which is the initial value of the equity method investment in Sonde. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the years ended December 31, 2023 and 2022, the Group recorded losses of $1,052 and $3,443, respectively, related to Sonde's equity method of accounting. As of December 31, 2023, the Sonde equity method investment has a balance of $3,185.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the activity related to the investment in associates balance for the years ended December 31, 2023 and 2022.</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:87.384%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Investment in Associates</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">As of January 1, 2022</span></div></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash investment in associates</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19,961 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additional investment as a result of settling the Backstop agreement (see above)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,424 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on dilution of interest in associate (*)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,793 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment in Sonde - deconsolidation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,680 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share in net loss of associates</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(27,749)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reversal of equity method losses recorded against LTI (due to decrease in the fair value of such LTI):</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,406)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share in other comprehensive loss of associates</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(166)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,390)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">As of December 31, 2022 and January 1, 2023</span></div></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,147 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share in net loss of associates</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,055)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share in other comprehensive income of associates</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">92 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">As of December 31, 2023</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,185</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">*    Gain on dilution of interest was further increased due to the receipt of Gelesis Earn-out Shares accounted for as investments held at fair value (see above).</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Summarized financial information</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the financial information of Gelesis as of December 31, 2022 and for the years ended December 31, 2022 and 2021, as included in its own financial statements, adjusted for fair value adjustments at deconsolidation and differences in accounting policies. The table also reconciles the summarized financial information to the carrying amount of the Group’s interest in Gelesis. As of December 31, 2023, the Group’s investment in Gelesis is $0 and Gelesis does not represent a significant equity method investment. As a result, such a disclosure for Gelesis is not presented for the year ended December 31, 2023. </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:0 1pt"></td></tr><tr style="height:12pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of and for the year ended December 31,</span></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Percentage ownership interest</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22.5 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-current assets</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">333,040 </span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current assets</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">23,495 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-current liabilities</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(99,053)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current liabilities</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(80,010)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-controlling interests and options issued to third parties</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(46,204)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net assets (deficit) attributable to shareholders of Gelesis Inc.</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">131,268 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Group's share of net assets (net deficit)</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">29,504 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Goodwill</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,858 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment </span></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(28,452)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Investment in associates</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,910 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr style="height:11pt"><td colspan="3" style="border-top:0.5pt solid #183964;padding:0 1pt"></td><td colspan="3" style="display:none"></td><td colspan="3" rowspan="2" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:11pt"><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25,767 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,185 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Loss from continuing operations (100%)</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(111,567)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(271,430)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive loss (100%)</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(112,285)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(273,005)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Group's share in net losses - limited to net investment amount (*)</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(24,306)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(73,703)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Group's share of total comprehensive loss - limited to net investment amount</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(24,472)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(73,703)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">*    For the year ended December 31, 2022, the amount includes $4,406 reversal of equity method losses recorded against long-term Interests ("LTI") due to the decrease in fair value of such LTI.</span></div>Investment in Notes from Associates <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Unsecured Promissory Note</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On July 27, 2022, the Group, as a lender, entered into an unsecured promissory note (the "Junior Note") with Gelesis, as a borrower, in the amount of $15,000. The Junior Note bears an annual interest rate of 15% per annum. The maturity date of the Junior Note is the earlier of December 31, 2023 or five business days following the consummation of a qualified financing by Gelesis. Based on the terms of the Junior Note, due to the option to convert to a variable amount of shares at the time of default, the Junior Note is required to be measured at fair value with changes in fair value recorded through profit and loss. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2023 and December 31, 2022 the fair value of the Junior Note was $0 and $16,501, respectively. In the year ended December 31, 2023, the Group recorded a loss of $16,501 for the change in the fair value of the Junior Note which was included in gain/(loss) on investments in notes from associates within the Consolidated Statement of Comprehensive Income/(Loss). The fair value of the Junior Note was determined to be $0 as of December 31, 2023 as Gelesis has ceased operations and filed for bankruptcy. In the year ended December 31, 2022, the Group recorded interest income of $963 and a gain of $539 for the change in the fair value of the Junior Note which was included in other income/(expense) in the Consolidated Statement of Comprehensive Income/(Loss). </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Senior Secured Convertible Promissory Notes</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2023, the Group entered into multiple agreements with Gelesis to purchase for $11,850 senior secured convertible promissory notes (the "Senior Notes") and warrants for share of Gelesis common stock. The initial fair value of the Senior Notes was determined to be $10,729 while $1,121 was determined to be the initial fair value of the warrants. The Senior Notes represent debt instruments that are presented at fair value through profit and loss as the amounts receivable do not solely represent payments of principal and interest as the Senior Notes are convertible into Gelesis common stock. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Senior Notes are secured by a first-priority lien on substantially all assets of Gelesis and the guarantors (other than the equity interests in, and assets held by Gelesis s.r.l., a subsidiary of Gelesis, and certain other exceptions).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In October 2023, Gelesis ceased operations and filed a voluntary petition for relief under the provisions of Chapter 7 of Title 11 of the United States Bankruptcy Code. Therefore, the Group determined that the fair value of the Senior Notes was $0 as of December 31, 2023 and the Group recorded a loss of $10,729 for the changes in the fair value of the Senior Notes. The loss was included in gain/(loss) on investments in notes from associates in the Consolidated Statement of Comprehensive Income/(Loss). </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On April 24, 2023, Vedanta closed the second tranche of its convertible debt for additional proceeds of $18,000, of which $5,000 were invested by the Group. The convertible debt carries an interest rate of 9 percent per annum. The debt has various conversion triggers and the conversion price is established at the lower of 80% of the equity price of the last financing round, or a certain pre-money valuation cap established in the agreement. If the convertible debt is not earlier converted or repaid, the entire outstanding amount of the convertible debt shall be due and payable upon the earliest to occur of (a) the later of (x) November 1, 2025 and (y) the date which is sixty (60) days after all amounts owed under, or in connection with, the loan Vedanta received from a certain investor have been paid in full, or (b) the consummation of a Deemed Liquidation Event (as defined in Vedanta’s Amended and Restated Certificate of Incorporation).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Due to the terms of the convertible debt, the investment in such convertible debt is measured at fair value with changes in the fair value recorded through profit and loss. During the years ended December 31, 2023, the Group recorded a loss of $400 for the changes in the fair value of the Vedanta convertible debt which was included in gain/(loss) on investments in notes from associates in the Consolidated Statement of Comprehensive Income/(Loss). </span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:112%">Following is the activity in respect of investments in notes from associates during the periods</span><span style="color:#000000;font-family:'Arial',sans-serif;font-size:11pt;font-weight:400;line-height:112%">.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:112%"> The fair value of the $4,600 note from associate as of December 31, 2023 is determined using unobservable Level 3 inputs. See Note 18. Financial Instruments for additional information.</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:87.384%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Investment in notes from associates</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment In Gelesis notes</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in the fair value of the notes</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,501 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2022 and January 1, 2023</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,501 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment In Gelesis notes</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,729 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment in Vedanta convertible debt</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in the fair value of the notes and convertible debt</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(27,630)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2023 </span></div></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,600</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div>
CY2022 ifrs-full Impairment Loss Recognised In Profit Or Loss
ImpairmentLossRecognisedInProfitOrLoss
8390000 usd
CY2021Q4 ifrs-full Investments In Associates
InvestmentsInAssociates
0 usd
CY2022 ifrs-full Purchase Of Interests In Associates
PurchaseOfInterestsInAssociates
19961000 usd
CY2022 ptv Spac Exchange Additional Investment In Associates
SPACExchangeAdditionalInvestmentInAssociates
8424000 usd
CY2022 ptv Gain Loss Recognized On Dilution Of Ownership Interest In Associate Without Earn Out Shares
GainLossRecognizedOnDilutionOfOwnershipInterestInAssociateWithoutEarnOutShares
13793000 usd
CY2022 ifrs-full Share Of Profit Loss Of Associates And Joint Ventures Accounted For Using Equity Method
ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod
-27749000 usd
CY2022 ptv Reversal Of Investment Loss In Associates Accounted For Using Equity Method
ReversalOfInvestmentLossInAssociatesAccountedForUsingEquityMethod
4406000 usd
CY2022 ifrs-full Impairment Loss Recognised In Profit Or Loss
ImpairmentLossRecognisedInProfitOrLoss
8390000 usd
CY2022Q4 ifrs-full Investments In Associates
InvestmentsInAssociates
9147000 usd
CY2023 ifrs-full Share Of Profit Loss Of Associates And Joint Ventures Accounted For Using Equity Method
ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod
-6055000 usd
CY2023Q4 ifrs-full Investments In Associates
InvestmentsInAssociates
3185000 usd
CY2022 ptv Reversal Of Investment Loss In Associates Accounted For Using Equity Method
ReversalOfInvestmentLossInAssociatesAccountedForUsingEquityMethod
4406000 usd
CY2023 ifrs-full General And Administrative Expense
GeneralAndAdministrativeExpense
53295000 usd
CY2022 ifrs-full General And Administrative Expense
GeneralAndAdministrativeExpense
60991000 usd
CY2021 ifrs-full General And Administrative Expense
GeneralAndAdministrativeExpense
57199000 usd
CY2023 ifrs-full Research And Development Expense
ResearchAndDevelopmentExpense
96235000 usd
CY2022 ifrs-full Research And Development Expense
ResearchAndDevelopmentExpense
152433000 usd
CY2021 ifrs-full Research And Development Expense
ResearchAndDevelopmentExpense
110471000 usd
CY2023 ifrs-full Operating Expense
OperatingExpense
149530000 usd
CY2022 ifrs-full Operating Expense
OperatingExpense
213425000 usd
CY2021 ifrs-full Operating Expense
OperatingExpense
167671000 usd
CY2023 ifrs-full Average Number Of Employees
AverageNumberOfEmployees
96 employee
CY2022 ifrs-full Average Number Of Employees
AverageNumberOfEmployees
201 employee
CY2021 ifrs-full Average Number Of Employees
AverageNumberOfEmployees
171 employee
CY2023 ptv Payroll Costs
PayrollCosts
45688000 usd
CY2022 ptv Payroll Costs
PayrollCosts
61643000 usd
CY2021 ptv Payroll Costs
PayrollCosts
55388000 usd
CY2023 ifrs-full Wages And Salaries
WagesAndSalaries
37084000 usd
CY2022 ifrs-full Wages And Salaries
WagesAndSalaries
41750000 usd
CY2021 ifrs-full Wages And Salaries
WagesAndSalaries
36792000 usd
CY2023 ifrs-full Employee Benefits Expense
EmployeeBenefitsExpense
2599000 usd
CY2022 ifrs-full Employee Benefits Expense
EmployeeBenefitsExpense
2908000 usd
CY2021 ifrs-full Employee Benefits Expense
EmployeeBenefitsExpense
2563000 usd
CY2023 ptv Payroll Taxes
PayrollTaxes
1590000 usd
CY2022 ptv Payroll Taxes
PayrollTaxes
2286000 usd
CY2021 ptv Payroll Taxes
PayrollTaxes
2084000 usd
CY2023 ifrs-full Expense From Sharebased Payment Transactions With Employees
ExpenseFromSharebasedPaymentTransactionsWithEmployees
4415000 usd
CY2022 ifrs-full Expense From Sharebased Payment Transactions With Employees
ExpenseFromSharebasedPaymentTransactionsWithEmployees
14699000 usd
CY2021 ifrs-full Expense From Sharebased Payment Transactions With Employees
ExpenseFromSharebasedPaymentTransactionsWithEmployees
13950000 usd
CY2023 ptv Payroll Costs
PayrollCosts
45688000 usd
CY2022 ptv Payroll Costs
PayrollCosts
61643000 usd
CY2021 ptv Payroll Costs
PayrollCosts
55388000 usd
CY2023 ifrs-full Amortisation Expense
AmortisationExpense
1979000 usd
CY2022 ifrs-full Amortisation Expense
AmortisationExpense
3048000 usd
CY2021 ifrs-full Amortisation Expense
AmortisationExpense
2940000 usd
CY2023 ifrs-full Depreciation Expense
DepreciationExpense
2955000 usd
CY2022 ifrs-full Depreciation Expense
DepreciationExpense
5845000 usd
CY2021 ifrs-full Depreciation Expense
DepreciationExpense
4347000 usd
CY2023 ifrs-full Depreciation And Amortisation Expense
DepreciationAndAmortisationExpense
4933000 usd
CY2022 ifrs-full Depreciation And Amortisation Expense
DepreciationAndAmortisationExpense
8893000 usd
CY2021 ifrs-full Depreciation And Amortisation Expense
DepreciationAndAmortisationExpense
7287000 usd
CY2023 ptv Other Selling General And Administrative Expense1
OtherSellingGeneralAndAdministrativeExpense1
25180000 usd
CY2022 ptv Other Selling General And Administrative Expense1
OtherSellingGeneralAndAdministrativeExpense1
31600000 usd
CY2021 ptv Other Selling General And Administrative Expense1
OtherSellingGeneralAndAdministrativeExpense1
26714000 usd
CY2023 ptv Other Research And Development Expenses
OtherResearchAndDevelopmentExpenses
73729000 usd
CY2022 ptv Other Research And Development Expenses
OtherResearchAndDevelopmentExpenses
111288000 usd
CY2021 ptv Other Research And Development Expenses
OtherResearchAndDevelopmentExpenses
78282000 usd
CY2023 ifrs-full Miscellaneous Other Operating Expense
MiscellaneousOtherOperatingExpense
98909000 usd
CY2022 ifrs-full Miscellaneous Other Operating Expense
MiscellaneousOtherOperatingExpense
142888000 usd
CY2021 ifrs-full Miscellaneous Other Operating Expense
MiscellaneousOtherOperatingExpense
104996000 usd
CY2023 ifrs-full Operating Expense
OperatingExpense
149530000 usd
CY2022 ifrs-full Operating Expense
OperatingExpense
213425000 usd
CY2021 ifrs-full Operating Expense
OperatingExpense
167671000 usd
CY2023 ifrs-full Disclosure Of Sharebased Payment Arrangements Explanatory
DisclosureOfSharebasedPaymentArrangementsExplanatory
<span style="color:#183964;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Share-based Payments</span><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payments includes stock options, time-based restricted stock units (“RSUs”) and performance-based RSUs in which the expense is recognized based on the grant date fair value of these awards, except for performance-based RSUs to executives that are treated as liability awards where expense is recognized based on reporting date fair value up until settlement date.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based Payment Expense</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group's share-based payment expense for the years ended December 31, 2023, 2022 and 2021, was $4,415, $14,699, and $13,950 respectively. The following table provides the classification of the Group’s consolidated share-based payment expense as reflected in the Consolidated Statement of Income/(Loss):</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Year ended December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,185</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,862 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,310 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,230</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,837 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,640 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,415</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,699 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,950 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Performance Share Plan</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In June 2015, the Group adopted the Performance Stock Plan (the “2015 PSP”). Under the 2015 PSP and subsequent amendments, awards of ordinary shares may be made to the Directors, senior managers and employees, and other individuals providing services to the Group up to a maximum authorized amount of 10.0 percent of the total ordinary shares outstanding. The shares have various vesting terms over a period of service between <span style="-sec-ix-hidden:f-1294">one</span> and four years, provided the recipient remains continuously engaged as a service provider. The options awards expire 10 years from the grant date.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In June 2023 the Group adopted a new Performance Stock Plan (the "2023 PSP") that has the same terms as the 2015 PSP but instituted for all new awards a limit of 10.0 percent of the total ordinary shares outstanding over a five-year period.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The share-based awards granted under the PSPs are generally equity-settled (see cash settlements below). As of December 31, 2023, the Group had issued 27,384,777 units of share-based awards under these plans.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSU activity for the years ended December 31, 2023, 2022 and 2021 is detailed as follows:</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Number of Shares/Units</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Weighted Average Grant Date Fair Value (GBP) (*)</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,422,582 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.46 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,195,133 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.15 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,176,695)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.93 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(808,305)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.25 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,632,715 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.91 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,309,883 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.76 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(696,398)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.80 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,155,420)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.67 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2022 and January 1, 2023</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,090,780</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.74</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,679,669 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.28 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(716,029)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,880,274)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.94 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2023</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7,174,146</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.10</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">*    For liability awards - based on fair value at reporting date.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span><br/></span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Each RSU entitles the holder to one ordinary share on vesting and the RSU awards are generally based on a vesting schedule over a <span style="-sec-ix-hidden:f-1328">one</span> to three-year requisite service period in which the Group recognizes compensation expense for the RSUs. Following vesting, each recipient will be required to make a payment of one pence per ordinary share on settlement of the RSUs. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs granted to the non-executive directors are time-based and equity-settled. The grant date fair value on such RSUs is recognized over the vesting term.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs granted to executives are performance-based and vesting of such RSUs is subject to the satisfaction of both performance and market conditions. The performance condition is based on the achievement of the Group's strategic targets. The market conditions are based on the achievement of the absolute total shareholder return (“TSR”), TSR as compared to the FTSE 250 Index, and TSR as compared to the MSCI Europe Health Care Index. The RSU award performance criteria have changed over time as the criteria are continually evaluated by the Group’s Remuneration Committee.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group recognizes the estimated fair value of performance-based awards with non-market conditions as share-based compensation expense over the performance period based upon its determination of whether it is probable that the performance targets will be achieved. The Group assesses the probability of achieving the performance targets at each reporting period. Cumulative adjustments, if any, are recorded to reflect subsequent changes in the estimated outcome of performance-related conditions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the performance-based awards with market conditions is based on the Monte Carlo simulation analysis utilizing a Geometric Brownian Motion process with 100,000 simulations to value those shares. The model considers share price volatility, risk-free rate and other covariance of comparable public companies and other market data to predict distribution of relative share performance.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Liability settled RSUs classification</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The RSUs to executives are treated as liability awards as the Group has a historical practice of settling these awards in cash, and as such adjusted to fair value at every reporting date until settlement with changes in fair value recorded in earnings as stock based compensation expense.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group incurred share-based payment expenses for RSUs of $827 (including $402 expense in respect of RSU liability awards), $1,637 (including $1,131 expense in respect of RSU liability awards), and $1,540 (including $589 expense in respect of RSU liability awards) for the years ended December 31, 2023, 2022 and 2021, respectively. The decrease in the share-based compensation expense in respect of the RSUs for the year ended December 31, 2023, as compared to the year ended December 31, 2022 is due to reduction in the fair value of the liability awards.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2023, the carrying amount of the RSU liability awards was $4,782, $1,281 current; $3,501 non current, out of which $1,283 related to awards that have met all their performance and market conditions.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Stock Options</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Stock option activity for the years ended December 31, 2023, 2022 and 2021, is detailed as follows:</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:52.839%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Number of Options</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average Exercise Price (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average of<br/>remaining contractual<br/>term (in years)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average Stock Price at Exercise (GBP)</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,916,086 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.81 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.38</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,424,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.34 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,238,187)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.70 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.63</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited and expired</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(687,781)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.53 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.19pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,773,873 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.42 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.50</span></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,414,118 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.58 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.29</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,881,000 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.04 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(577,022)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.50 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.43</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited and expired</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,924,215)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.89 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.19pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2022 and January 1, 2023</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,185,216</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.03</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.21</span></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at December 31, 2022 and January 1, 2023</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">17,793,881</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.31</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.03</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,120,975 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.22 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(534,034)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.71 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.46</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited and expired</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,424,232)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.40 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2023</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">9,065,830</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.19</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.01</span></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at December 31, 2023</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16,956,590</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.29</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7.20</span></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the stock options awarded by the Group was estimated at the grant date using the Black-Scholes option valuation model, considering the terms and conditions upon which options were granted, with the following weighted-average assumptions:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">At December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected volatility</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">43.69</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41.70 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41.05 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected terms (in years)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.16</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.11</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.16</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Risk-free interest rate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.04</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.13 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.06 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected dividend yield</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercise price (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.22</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.04</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.34</span></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Underlying stock price (GBP)</span></td><td colspan="3" style="border-bottom:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.22</span></td><td colspan="3" style="border-bottom:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.04</span></td><td colspan="3" style="border-bottom:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.34</span></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">These assumptions resulted in an estimated weighted-average grant-date fair value per share of stock options granted during the years ended December 31, 2023, 2022 and 2021 of $1.37 ,$1.15 and $1.87, respectively.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group incurred share-based payment expense for the stock options of $3,310, $8,351 and $6,158 for the years ended December 31, 2023, 2022 and 2021, respectively. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For shares outstanding as of December 31, 2023, the range of exercise prices is detailed as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Range of Exercise Prices (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Options<br/>Outstanding</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd<br/>Average<br/>Exercise<br/>Price (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average of<br/>remaining contractual<br/>term (in years)</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.01</span></div></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">439,490 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.76</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.00 to 2.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,989,572 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.54 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.64</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.00 to 3.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,664,028 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.25 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.55</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.00 to 4.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,863,500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.33 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7.10</span></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16,956,590</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.29</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7.20</span></td></tr></table></div><div style="margin-top:6pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary Plans</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain subsidiaries of the Group have adopted stock option plans. A summary of stock option activity by number of shares in these subsidiaries is presented in the following table:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:17.384%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.324%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.417%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Outstanding as of January 1, 2023</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Granted During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Exercised During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Expired During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Forfeited During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Deconsolidation During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Outstanding as of December 31, 2023</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">344,500</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">344,500</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,776,120</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,170,547)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(605,573)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,824,576</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,313)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(29,607)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,793,656)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:17.233%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.475%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.417%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding as of January 1, 2022</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Granted During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Exercised During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Expired During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Forfeited During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Deconsolidation During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding as of December 31, 2022</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">349,500 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">45,000 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(50,000)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">344,500 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,686,120 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">90,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,776,120 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,049,004 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,049,004)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,991,637 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">490,506 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(400,000)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(65,235)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(192,332)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,824,576 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:17.233%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.475%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.417%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding as of January 1, 2021</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Granted During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Exercised During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Expired During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Forfeited During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Deconsolidation During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding as of December 31, 2021</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,888,168 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">197,398 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,373,750)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(506,260)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,205,556)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">962,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(525,000)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(87,500)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">349,500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,309,040 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,383,080 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,000)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,686,120 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,192,834 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(51,507)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(92,323)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,049,004 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,741,888 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">451,532 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(52,938)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(76,491)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(72,354)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,991,637 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The weighted-average exercise prices and remaining contractual life for the options outstanding as of December 31, 2023, were as follows:</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding at December 31, 2023</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of options</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average exercise price</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average contractual life outstanding</span></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="border-bottom:0.25pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">344,500</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.91</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.25pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3.92</span></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">There were no grants in 2023 under any of the subsidiary option plans. The weighted average exercise prices for the options granted for the years ended December 31, 2022 and 2021, were as follows:</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td><td colspan="3" style="display:none"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.02 </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="3" style="display:none"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.86 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.86 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></div></td><td colspan="3" style="display:none"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14.94 </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19.69 </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The weighted average exercise prices for options forfeited during the year ended December 31, 2023, were as follows: </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Forfeited during the year ended December 31, 2023</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of options</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average exercise price</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">605,573</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.86</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">29,607</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">17.06</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The weighted average exercise prices for options exercisable as of December 31, 2023, were as follows:</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Exercisable at December 31, 2023</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of Options</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average exercise price</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Exercise Price Range<br/>$</span></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #494949;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #494949;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">329,500</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #494949;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #494949;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.99</span></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #494949;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.02-2.36</span></div></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">There were no subsidiary options exercised during the year ended December 31, 2023.</span></div>For the years ended December 31, 2023, 2022 and 2021, the subsidiaries incurred share-based payment expense of $277, $4,711 and $6,252, respectively.
CY2023 ifrs-full Expense From Sharebased Payment Transactions With Employees
ExpenseFromSharebasedPaymentTransactionsWithEmployees
4415000 usd
CY2022 ifrs-full Expense From Sharebased Payment Transactions With Employees
ExpenseFromSharebasedPaymentTransactionsWithEmployees
14699000 usd
CY2021 ifrs-full Expense From Sharebased Payment Transactions With Employees
ExpenseFromSharebasedPaymentTransactionsWithEmployees
13950000 usd
CY2023 ifrs-full Expense From Sharebased Payment Transactions With Employees
ExpenseFromSharebasedPaymentTransactionsWithEmployees
4415000 usd
CY2022 ifrs-full Expense From Sharebased Payment Transactions With Employees
ExpenseFromSharebasedPaymentTransactionsWithEmployees
14699000 usd
CY2021 ifrs-full Expense From Sharebased Payment Transactions With Employees
ExpenseFromSharebasedPaymentTransactionsWithEmployees
13950000 usd
CY2023 ifrs-full Disclosure Of Number And Weighted Average Exercise Prices Of Other Equity Instruments Explanatory
DisclosureOfNumberAndWeightedAverageExercisePricesOfOtherEquityInstrumentsExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSU activity for the years ended December 31, 2023, 2022 and 2021 is detailed as follows:</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Number of Shares/Units</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Weighted Average Grant Date Fair Value (GBP) (*)</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,422,582 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.46 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,195,133 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.15 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,176,695)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.93 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(808,305)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.25 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,632,715 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.91 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,309,883 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.76 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(696,398)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.80 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,155,420)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.67 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2022 and January 1, 2023</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,090,780</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.74</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,679,669 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.28 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(716,029)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.00 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,880,274)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.94 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2023</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7,174,146</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.10</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">*    For liability awards - based on fair value at reporting date.</span></div>
CY2023 ptv Share Based Compensation Arrangement By Share Based Payment Award Number Of Common Shares Redeemed Per Restricted Share Unit
ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfCommonSharesRedeemedPerRestrictedShareUnit
1 shares
CY2023 ifrs-full Disclosure Of Number And Weighted Average Exercise Prices Of Share Options Explanatory
DisclosureOfNumberAndWeightedAverageExercisePricesOfShareOptionsExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Stock option activity for the years ended December 31, 2023, 2022 and 2021, is detailed as follows:</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:52.839%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Number of Options</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average Exercise Price (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average of<br/>remaining contractual<br/>term (in years)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average Stock Price at Exercise (GBP)</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,916,086 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.81 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.38</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,424,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.34 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,238,187)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.70 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.63</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited and expired</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(687,781)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.53 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.19pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,773,873 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.42 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.50</span></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,414,118 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.58 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.29</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,881,000 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.04 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(577,022)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.50 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.43</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited and expired</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,924,215)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.89 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.19pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2022 and January 1, 2023</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,185,216</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.03</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.21</span></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at December 31, 2022 and January 1, 2023</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">17,793,881</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.31</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.03</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,120,975 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.22 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(534,034)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.71 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.46</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited and expired</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,424,232)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.40 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2023</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">9,065,830</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.19</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.01</span></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at December 31, 2023</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16,956,590</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.29</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7.20</span></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"></td></tr></table></div>
CY2020Q4 ifrs-full Number Of Outstanding Share Options
NumberOfOutstandingShareOptions
10916086 shares
CY2020Q4 ifrs-full Weighted Average Exercise Price Of Share Options Outstanding In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsOutstandingInSharebasedPaymentArrangement2019
1.81
CY2020 ifrs-full Weighted Average Remaining Contractual Life Of Outstanding Share Options2019
WeightedAverageRemainingContractualLifeOfOutstandingShareOptions2019
P8Y4M17D
CY2021 ifrs-full Number Of Share Options Granted In Sharebased Payment Arrangement
NumberOfShareOptionsGrantedInSharebasedPaymentArrangement
5424000 shares
CY2021 ifrs-full Weighted Average Exercise Price Of Share Options Granted In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsGrantedInSharebasedPaymentArrangement2019
3.34
CY2021 ifrs-full Number Of Share Options Exercised In Sharebased Payment Arrangement
NumberOfShareOptionsExercisedInSharebasedPaymentArrangement
2238187 shares
CY2021 ifrs-full Weighted Average Exercise Price Of Share Options Exercised In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsExercisedInSharebasedPaymentArrangement2019
0.70
CY2021 ptv Weighted Average Stock Price Of Share Options Exercised In Share Based Payment Arrangement
WeightedAverageStockPriceOfShareOptionsExercisedInShareBasedPaymentArrangement
3.63
CY2021 ptv Number Of Share Options Forfeited And Expired In Share Based Payment Arrangement
NumberOfShareOptionsForfeitedAndExpiredInShareBasedPaymentArrangement
687781 shares
CY2021 ptv Weighted Average Exercise Price Of Share Options Forfeited And Expired In Share Based Payment Arrangement
WeightedAverageExercisePriceOfShareOptionsForfeitedAndExpiredInShareBasedPaymentArrangement
2.53
CY2021Q4 ifrs-full Number Of Share Options Exercisable In Sharebased Payment Arrangement
NumberOfShareOptionsExercisableInSharebasedPaymentArrangement
4773873 shares
CY2021Q4 ifrs-full Weighted Average Exercise Price Of Share Options Exercisable In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsExercisableInSharebasedPaymentArrangement2019
1.42
CY2021 ptv Weighted Average Remaining Contractual Life Of Options Excisable
WeightedAverageRemainingContractualLifeOfOptionsExcisable
P6Y6M
CY2021Q4 ifrs-full Number Of Outstanding Share Options
NumberOfOutstandingShareOptions
13414118 shares
CY2021Q4 ifrs-full Weighted Average Exercise Price Of Share Options Outstanding In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsOutstandingInSharebasedPaymentArrangement2019
2.58
CY2021 ifrs-full Weighted Average Remaining Contractual Life Of Outstanding Share Options2019
WeightedAverageRemainingContractualLifeOfOutstandingShareOptions2019
P8Y3M14D
CY2022 ifrs-full Number Of Share Options Granted In Sharebased Payment Arrangement
NumberOfShareOptionsGrantedInSharebasedPaymentArrangement
8881000 shares
CY2022 ifrs-full Weighted Average Exercise Price Of Share Options Granted In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsGrantedInSharebasedPaymentArrangement2019
2.04
CY2022 ifrs-full Number Of Share Options Exercised In Sharebased Payment Arrangement
NumberOfShareOptionsExercisedInSharebasedPaymentArrangement
577022 shares
CY2022 ifrs-full Weighted Average Exercise Price Of Share Options Exercised In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsExercisedInSharebasedPaymentArrangement2019
0.50
CY2022 ptv Weighted Average Stock Price Of Share Options Exercised In Share Based Payment Arrangement
WeightedAverageStockPriceOfShareOptionsExercisedInShareBasedPaymentArrangement
2.43
CY2022 ptv Number Of Share Options Forfeited And Expired In Share Based Payment Arrangement
NumberOfShareOptionsForfeitedAndExpiredInShareBasedPaymentArrangement
3924215 shares
CY2022 ptv Weighted Average Exercise Price Of Share Options Forfeited And Expired In Share Based Payment Arrangement
WeightedAverageExercisePriceOfShareOptionsForfeitedAndExpiredInShareBasedPaymentArrangement
2.89
CY2022Q4 ifrs-full Number Of Share Options Exercisable In Sharebased Payment Arrangement
NumberOfShareOptionsExercisableInSharebasedPaymentArrangement
6185216 shares
CY2022Q4 ifrs-full Weighted Average Exercise Price Of Share Options Exercisable In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsExercisableInSharebasedPaymentArrangement2019
2.03
CY2022 ptv Weighted Average Remaining Contractual Life Of Options Excisable
WeightedAverageRemainingContractualLifeOfOptionsExcisable
P6Y2M15D
CY2022Q4 ifrs-full Number Of Outstanding Share Options
NumberOfOutstandingShareOptions
17793881 shares
CY2022Q4 ifrs-full Weighted Average Exercise Price Of Share Options Outstanding In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsOutstandingInSharebasedPaymentArrangement2019
2.31
CY2022 ifrs-full Weighted Average Remaining Contractual Life Of Outstanding Share Options2019
WeightedAverageRemainingContractualLifeOfOutstandingShareOptions2019
P8Y10D
CY2023 ifrs-full Number Of Share Options Granted In Sharebased Payment Arrangement
NumberOfShareOptionsGrantedInSharebasedPaymentArrangement
3120975 shares
CY2023 ifrs-full Weighted Average Exercise Price Of Share Options Granted In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsGrantedInSharebasedPaymentArrangement2019
2.22
CY2023 ifrs-full Number Of Share Options Exercised In Sharebased Payment Arrangement
NumberOfShareOptionsExercisedInSharebasedPaymentArrangement
534034 shares
CY2023 ifrs-full Weighted Average Exercise Price Of Share Options Exercised In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsExercisedInSharebasedPaymentArrangement2019
1.71
CY2023 ptv Weighted Average Stock Price Of Share Options Exercised In Share Based Payment Arrangement
WeightedAverageStockPriceOfShareOptionsExercisedInShareBasedPaymentArrangement
2.46
CY2023 ptv Number Of Share Options Forfeited And Expired In Share Based Payment Arrangement
NumberOfShareOptionsForfeitedAndExpiredInShareBasedPaymentArrangement
3424232 shares
CY2023 ptv Weighted Average Exercise Price Of Share Options Forfeited And Expired In Share Based Payment Arrangement
WeightedAverageExercisePriceOfShareOptionsForfeitedAndExpiredInShareBasedPaymentArrangement
2.40
CY2023Q4 ifrs-full Number Of Share Options Exercisable In Sharebased Payment Arrangement
NumberOfShareOptionsExercisableInSharebasedPaymentArrangement
9065830 shares
CY2023Q4 ifrs-full Weighted Average Exercise Price Of Share Options Exercisable In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsExercisableInSharebasedPaymentArrangement2019
2.19
CY2023 ptv Weighted Average Remaining Contractual Life Of Options Excisable
WeightedAverageRemainingContractualLifeOfOptionsExcisable
P6Y3D
CY2023Q4 ifrs-full Number Of Outstanding Share Options
NumberOfOutstandingShareOptions
16956590 shares
CY2023Q4 ifrs-full Weighted Average Exercise Price Of Share Options Outstanding In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsOutstandingInSharebasedPaymentArrangement2019
2.29
CY2023 ifrs-full Weighted Average Remaining Contractual Life Of Outstanding Share Options2019
WeightedAverageRemainingContractualLifeOfOutstandingShareOptions2019
P7Y2M12D
CY2023 ifrs-full Disclosure Of Terms And Conditions Of Sharebased Payment Arrangement Explanatory
DisclosureOfTermsAndConditionsOfSharebasedPaymentArrangementExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the stock options awarded by the Group was estimated at the grant date using the Black-Scholes option valuation model, considering the terms and conditions upon which options were granted, with the following weighted-average assumptions:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">At December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected volatility</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">43.69</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41.70 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41.05 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected terms (in years)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.16</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.11</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.16</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Risk-free interest rate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.04</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.13 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.06 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected dividend yield</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercise price (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.22</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.04</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.34</span></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Underlying stock price (GBP)</span></td><td colspan="3" style="border-bottom:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.22</span></td><td colspan="3" style="border-bottom:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.04</span></td><td colspan="3" style="border-bottom:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.34</span></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr></table></div>
CY2023 ifrs-full Description Of Expected Volatility Share Options Granted
DescriptionOfExpectedVolatilityShareOptionsGranted
0.4369
CY2022 ifrs-full Description Of Expected Volatility Share Options Granted
DescriptionOfExpectedVolatilityShareOptionsGranted
0.4170
CY2021 ifrs-full Description Of Expected Volatility Share Options Granted
DescriptionOfExpectedVolatilityShareOptionsGranted
0.4105
CY2023 ifrs-full Description Of Option Life Share Options Granted
DescriptionOfOptionLifeShareOptionsGranted
6.16 y
CY2022 ifrs-full Description Of Option Life Share Options Granted
DescriptionOfOptionLifeShareOptionsGranted
6.11 y
CY2021 ifrs-full Description Of Option Life Share Options Granted
DescriptionOfOptionLifeShareOptionsGranted
6.16 y
CY2023 ifrs-full Description Of Risk Free Interest Rate Share Options Granted
DescriptionOfRiskFreeInterestRateShareOptionsGranted
0.0404
CY2022 ifrs-full Description Of Risk Free Interest Rate Share Options Granted
DescriptionOfRiskFreeInterestRateShareOptionsGranted
0.0213
CY2021 ifrs-full Description Of Risk Free Interest Rate Share Options Granted
DescriptionOfRiskFreeInterestRateShareOptionsGranted
0.0106
CY2023 ifrs-full Expected Dividend Share Options Granted
ExpectedDividendShareOptionsGranted
0 usd
CY2022 ifrs-full Expected Dividend Share Options Granted
ExpectedDividendShareOptionsGranted
0 usd
CY2021 ifrs-full Expected Dividend Share Options Granted
ExpectedDividendShareOptionsGranted
0 usd
CY2023 ifrs-full Exercise Price Share Options Granted2019
ExercisePriceShareOptionsGranted2019
2.22
CY2022 ifrs-full Exercise Price Share Options Granted2019
ExercisePriceShareOptionsGranted2019
2.04
CY2021 ifrs-full Exercise Price Share Options Granted2019
ExercisePriceShareOptionsGranted2019
3.34
CY2023 ifrs-full Weighted Average Share Price Share Options Granted2019
WeightedAverageSharePriceShareOptionsGranted2019
2.22
CY2022 ifrs-full Weighted Average Share Price Share Options Granted2019
WeightedAverageSharePriceShareOptionsGranted2019
2.04
CY2021 ifrs-full Weighted Average Share Price Share Options Granted2019
WeightedAverageSharePriceShareOptionsGranted2019
3.34
CY2023 ifrs-full Weighted Average Share Price Share Options Granted2019
WeightedAverageSharePriceShareOptionsGranted2019
1.37
CY2022 ifrs-full Weighted Average Share Price Share Options Granted2019
WeightedAverageSharePriceShareOptionsGranted2019
1.15
CY2021 ifrs-full Weighted Average Share Price Share Options Granted2019
WeightedAverageSharePriceShareOptionsGranted2019
1.87
CY2023 ifrs-full Disclosure Of Range Of Exercise Prices Of Outstanding Share Options Explanatory
DisclosureOfRangeOfExercisePricesOfOutstandingShareOptionsExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For shares outstanding as of December 31, 2023, the range of exercise prices is detailed as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.844%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Range of Exercise Prices (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Options<br/>Outstanding</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd<br/>Average<br/>Exercise<br/>Price (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average of<br/>remaining contractual<br/>term (in years)</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.01</span></div></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">439,490 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.76</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.00 to 2.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,989,572 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.54 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.64</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.00 to 3.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,664,028 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.25 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.55</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.00 to 4.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,863,500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.33 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7.10</span></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16,956,590</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.29</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7.20</span></td></tr></table></div>
CY2023Q4 ifrs-full Number Of Outstanding Share Options
NumberOfOutstandingShareOptions
16956590 shares
CY2023Q4 ifrs-full Weighted Average Exercise Price Of Share Options Outstanding In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsOutstandingInSharebasedPaymentArrangement2019
2.29
CY2023 ifrs-full Weighted Average Remaining Contractual Life Of Outstanding Share Options2019
WeightedAverageRemainingContractualLifeOfOutstandingShareOptions2019
P7Y2M12D
CY2023 ifrs-full Disclosure Of Finance Cost Explanatory
DisclosureOfFinanceCostExplanatory
Finance Income/(Costs), net <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table shows the breakdown of finance income and costs:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance income</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest income from financial assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16,012</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,799 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">214 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance income</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16,012</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,799 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">214 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance costs</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contractual interest expense on notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,422)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(212)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,031)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest expense on other borrowings</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(363)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,759)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,502)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest expense on lease liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,544)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,982)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,181)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on foreign currency exchange</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(94)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(56)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance cost – contractual</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,424)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,939)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,771)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) from change in fair value of warrant liability</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">33</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,740 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,419 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) from change in fair value of preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,617</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">130,825 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,362 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) from change in fair value of convertible debt</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(502)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(175)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance income/(costs) – fair value accounting</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,650</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">137,063 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,606 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance costs - non cash interest expense related to sale of future royalties</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(10,159)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance income/(costs), net</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,078</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">138,924 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,050 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div>
CY2023 ifrs-full Disclosure Of Finance Income Expense Explanatory
DisclosureOfFinanceIncomeExpenseExplanatory
Finance Income/(Costs), net <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table shows the breakdown of finance income and costs:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance income</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest income from financial assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16,012</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,799 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">214 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance income</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16,012</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,799 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">214 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance costs</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contractual interest expense on notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,422)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(212)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,031)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest expense on other borrowings</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(363)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,759)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,502)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest expense on lease liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,544)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,982)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,181)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on foreign currency exchange</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(94)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(56)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance cost – contractual</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,424)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,939)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,771)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) from change in fair value of warrant liability</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">33</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,740 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,419 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) from change in fair value of preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,617</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">130,825 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,362 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) from change in fair value of convertible debt</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(502)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(175)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance income/(costs) – fair value accounting</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,650</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">137,063 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,606 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance costs - non cash interest expense related to sale of future royalties</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(10,159)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance income/(costs), net</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,078</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">138,924 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,050 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div>
CY2023 ptv Interest Income From Financial Assets
InterestIncomeFromFinancialAssets
16012000 usd
CY2022 ptv Interest Income From Financial Assets
InterestIncomeFromFinancialAssets
5799000 usd
CY2021 ptv Interest Income From Financial Assets
InterestIncomeFromFinancialAssets
214000 usd
CY2023 ifrs-full Finance Income
FinanceIncome
16012000 usd
CY2022 ifrs-full Finance Income
FinanceIncome
5799000 usd
CY2021 ifrs-full Finance Income
FinanceIncome
214000 usd
CY2023 ptv Contractual Interest Expense On Notes
ContractualInterestExpenseOnNotes
1422000 usd
CY2022 ptv Contractual Interest Expense On Notes
ContractualInterestExpenseOnNotes
212000 usd
CY2021 ptv Contractual Interest Expense On Notes
ContractualInterestExpenseOnNotes
1031000 usd
CY2023 ifrs-full Interest Expense On Borrowings
InterestExpenseOnBorrowings
363000 usd
CY2022 ifrs-full Interest Expense On Borrowings
InterestExpenseOnBorrowings
1759000 usd
CY2021 ifrs-full Interest Expense On Borrowings
InterestExpenseOnBorrowings
1502000 usd
CY2023 ifrs-full Interest Expense On Lease Liabilities
InterestExpenseOnLeaseLiabilities
1544000 usd
CY2022 ifrs-full Interest Expense On Lease Liabilities
InterestExpenseOnLeaseLiabilities
1982000 usd
CY2021 ifrs-full Interest Expense On Lease Liabilities
InterestExpenseOnLeaseLiabilities
2181000 usd
CY2023 ptv Gain Loss On Foreign Currency Exchange In Finance Costs
GainLossOnForeignCurrencyExchangeInFinanceCosts
-94000 usd
CY2022 ptv Gain Loss On Foreign Currency Exchange In Finance Costs
GainLossOnForeignCurrencyExchangeInFinanceCosts
14000 usd
CY2021 ptv Gain Loss On Foreign Currency Exchange In Finance Costs
GainLossOnForeignCurrencyExchangeInFinanceCosts
-56000 usd
CY2023 ifrs-full Finance Costs
FinanceCosts
3424000 usd
CY2022 ifrs-full Finance Costs
FinanceCosts
3939000 usd
CY2021 ifrs-full Finance Costs
FinanceCosts
4771000 usd
CY2023 ptv Gain Loss From Change In Fair Value Of Warrant Liability
GainLossFromChangeInFairValueOfWarrantLiability
33000 usd
CY2022 ptv Gain Loss From Change In Fair Value Of Warrant Liability
GainLossFromChangeInFairValueOfWarrantLiability
6740000 usd
CY2021 ptv Gain Loss From Change In Fair Value Of Warrant Liability
GainLossFromChangeInFairValueOfWarrantLiability
1419000 usd
CY2023 ptv Gain Loss From Change In Fair Value Of Preferred Shares
GainLossFromChangeInFairValueOfPreferredShares
2617000 usd
CY2022 ptv Gain Loss From Change In Fair Value Of Preferred Shares
GainLossFromChangeInFairValueOfPreferredShares
130825000 usd
CY2021 ptv Gain Loss From Change In Fair Value Of Preferred Shares
GainLossFromChangeInFairValueOfPreferredShares
8362000 usd
CY2023 ptv Gain Loss From Change In Fair Value Of Convertible Debt
GainLossFromChangeInFairValueOfConvertibleDebt
0 usd
CY2022 ptv Gain Loss From Change In Fair Value Of Convertible Debt
GainLossFromChangeInFairValueOfConvertibleDebt
-502000 usd
CY2021 ptv Gain Loss From Change In Fair Value Of Convertible Debt
GainLossFromChangeInFairValueOfConvertibleDebt
-175000 usd
CY2023 ifrs-full Gains Losses Recognised In Profit Or Loss Fair Value Measurement Liabilities
GainsLossesRecognisedInProfitOrLossFairValueMeasurementLiabilities
2650000 usd
CY2022 ifrs-full Gains Losses Recognised In Profit Or Loss Fair Value Measurement Liabilities
GainsLossesRecognisedInProfitOrLossFairValueMeasurementLiabilities
137063000 usd
CY2021 ifrs-full Gains Losses Recognised In Profit Or Loss Fair Value Measurement Liabilities
GainsLossesRecognisedInProfitOrLossFairValueMeasurementLiabilities
9606000 usd
CY2023 ptv Noncash Interest Expense Royalty Liability
NoncashInterestExpenseRoyaltyLiability
10159000 usd
CY2022 ptv Noncash Interest Expense Royalty Liability
NoncashInterestExpenseRoyaltyLiability
0 usd
CY2021 ptv Noncash Interest Expense Royalty Liability
NoncashInterestExpenseRoyaltyLiability
0 usd
CY2023 ifrs-full Finance Income Cost
FinanceIncomeCost
5078000 usd
CY2022 ifrs-full Finance Income Cost
FinanceIncomeCost
138924000 usd
CY2021 ifrs-full Finance Income Cost
FinanceIncomeCost
5050000 usd
CY2023 ifrs-full Disclosure Of Earnings Per Share Explanatory
DisclosureOfEarningsPerShareExplanatory
Earnings/(Loss) per Share <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basic earnings/(loss) per share is calculated by dividing the Group's net income or loss for the year attributable to ordinary shareholders by the weighted average number of ordinary shares outstanding, net of treasury shares.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Diluted EPS is calculated by dividing the Group's net income or loss for the year by the weighted average number of ordinary shares outstanding, net of treasury shares, plus the weighted average number of ordinary shares that would be issued at conversion of all the dilutive potential ordinary shares into ordinary shares. Dilutive effects arise from equity-settled shares from the Group's share-based plans. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For the years ended December 31, 2023, 2022 and 2021, the Group incurred a net loss and therefore all outstanding potential securities were considered anti-dilutive. The amount of potential securities that were excluded from the diluted calculation amounted to 1,509,900, 3,134,131 and 6,553,905 shares, respectively. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Earnings/(Loss) Attributable to Owners of the Group:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:28.596%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.417%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Basic $</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Diluted $</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic $</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted $</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic $</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted $</span></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year, attributable to the owners of the Group</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(65,697)</span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(65,697)</span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(50,354)</span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(50,354)</span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(60,558)</span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(60,558)</span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Weighted-Average Number of Ordinary Shares:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:28.596%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.417%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Basic</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Diluted</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.1pt;font-weight:400;line-height:120%">Issued ordinary shares at January 1,</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">278,566,306</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">278,566,306</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">287,796,585 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">287,796,585 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">285,885,025 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">285,885,025 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effect of shares issued &amp; treasury shares purchased</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,263,773)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,263,773)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,037,150)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,037,150)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">705,958 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">705,958 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Weighted average number of ordinary shares at December 31,</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">276,302,533</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">276,302,533</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.5pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.5pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">284,759,435 </span></td><td style="border-bottom:0.5pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">284,759,435 </span></td><td style="border-bottom:0.5pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.5pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.5pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">286,590,983 </span></td><td style="border-bottom:0.5pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">286,590,983 </span></td><td style="border-bottom:0.5pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Earnings/(Loss) per Share:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:28.596%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.417%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Basic $</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Diluted $</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic $</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted $</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic $</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted $</span></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basic and diluted earnings/(loss) per share</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(0.24)</span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(0.24)</span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.18)</span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.18)</span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.21)</span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.21)</span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div>
CY2023 ifrs-full Number Of Potential Ordinary Shares That Are Antidilutive In Period Presented
NumberOfPotentialOrdinarySharesThatAreAntidilutiveInPeriodPresented
1509900 shares
CY2022 ifrs-full Number Of Potential Ordinary Shares That Are Antidilutive In Period Presented
NumberOfPotentialOrdinarySharesThatAreAntidilutiveInPeriodPresented
3134131 shares
CY2021 ifrs-full Number Of Potential Ordinary Shares That Are Antidilutive In Period Presented
NumberOfPotentialOrdinarySharesThatAreAntidilutiveInPeriodPresented
6553905 shares
CY2023 ifrs-full Profit Loss Attributable To Ordinary Equity Holders Of Parent Entity
ProfitLossAttributableToOrdinaryEquityHoldersOfParentEntity
-65697000 usd
CY2023 ifrs-full Profit Loss Attributable To Ordinary Equity Holders Of Parent Entity Including Dilutive Effects
ProfitLossAttributableToOrdinaryEquityHoldersOfParentEntityIncludingDilutiveEffects
-65697000 usd
CY2022 ifrs-full Profit Loss Attributable To Ordinary Equity Holders Of Parent Entity
ProfitLossAttributableToOrdinaryEquityHoldersOfParentEntity
-50354000 usd
CY2022 ifrs-full Profit Loss Attributable To Ordinary Equity Holders Of Parent Entity Including Dilutive Effects
ProfitLossAttributableToOrdinaryEquityHoldersOfParentEntityIncludingDilutiveEffects
-50354000 usd
CY2021 ifrs-full Profit Loss Attributable To Ordinary Equity Holders Of Parent Entity
ProfitLossAttributableToOrdinaryEquityHoldersOfParentEntity
-60558000 usd
CY2021 ifrs-full Profit Loss Attributable To Ordinary Equity Holders Of Parent Entity Including Dilutive Effects
ProfitLossAttributableToOrdinaryEquityHoldersOfParentEntityIncludingDilutiveEffects
-60558000 usd
CY2022Q4 ifrs-full Number Of Shares Outstanding
NumberOfSharesOutstanding
278566306 shares
CY2022Q4 ifrs-full Number Of Shares Outstanding
NumberOfSharesOutstanding
278566306 shares
CY2021Q4 ifrs-full Number Of Shares Outstanding
NumberOfSharesOutstanding
287796585 shares
CY2021Q4 ifrs-full Number Of Shares Outstanding
NumberOfSharesOutstanding
287796585 shares
CY2020Q4 ifrs-full Number Of Shares Outstanding
NumberOfSharesOutstanding
285885025 shares
CY2020Q4 ifrs-full Number Of Shares Outstanding
NumberOfSharesOutstanding
285885025 shares
CY2023 ptv Dilutive Effect Of All Instruments On Weighted Average Number Of Ordinary Shares Including Effect Of Treasury Shares Purchased
DilutiveEffectOfAllInstrumentsOnWeightedAverageNumberOfOrdinarySharesIncludingEffectOfTreasurySharesPurchased
2263773 shares
CY2023 ptv Dilutive Effect Of All Instruments On Weighted Average Number Of Ordinary Shares Including Effect Of Treasury Shares Purchased
DilutiveEffectOfAllInstrumentsOnWeightedAverageNumberOfOrdinarySharesIncludingEffectOfTreasurySharesPurchased
2263773 shares
CY2022 ptv Dilutive Effect Of All Instruments On Weighted Average Number Of Ordinary Shares Including Effect Of Treasury Shares Purchased
DilutiveEffectOfAllInstrumentsOnWeightedAverageNumberOfOrdinarySharesIncludingEffectOfTreasurySharesPurchased
3037150 shares
CY2022 ptv Dilutive Effect Of All Instruments On Weighted Average Number Of Ordinary Shares Including Effect Of Treasury Shares Purchased
DilutiveEffectOfAllInstrumentsOnWeightedAverageNumberOfOrdinarySharesIncludingEffectOfTreasurySharesPurchased
3037150 shares
CY2021 ptv Dilutive Effect Of All Instruments On Weighted Average Number Of Ordinary Shares Including Effect Of Treasury Shares Purchased
DilutiveEffectOfAllInstrumentsOnWeightedAverageNumberOfOrdinarySharesIncludingEffectOfTreasurySharesPurchased
-705958 shares
CY2021 ptv Dilutive Effect Of All Instruments On Weighted Average Number Of Ordinary Shares Including Effect Of Treasury Shares Purchased
DilutiveEffectOfAllInstrumentsOnWeightedAverageNumberOfOrdinarySharesIncludingEffectOfTreasurySharesPurchased
-705958 shares
CY2023 ifrs-full Weighted Average Shares
WeightedAverageShares
276302533 shares
CY2023 ifrs-full Adjusted Weighted Average Shares
AdjustedWeightedAverageShares
276302533 shares
CY2022 ifrs-full Weighted Average Shares
WeightedAverageShares
284759435 shares
CY2022 ifrs-full Adjusted Weighted Average Shares
AdjustedWeightedAverageShares
284759435 shares
CY2021 ifrs-full Weighted Average Shares
WeightedAverageShares
286590983 shares
CY2021 ifrs-full Adjusted Weighted Average Shares
AdjustedWeightedAverageShares
286590983 shares
CY2023 ifrs-full Basic Earnings Loss Per Share
BasicEarningsLossPerShare
-0.24
CY2023 ifrs-full Diluted Earnings Loss Per Share
DilutedEarningsLossPerShare
-0.24
CY2022 ifrs-full Basic Earnings Loss Per Share
BasicEarningsLossPerShare
-0.18
CY2022 ifrs-full Diluted Earnings Loss Per Share
DilutedEarningsLossPerShare
-0.18
CY2021 ifrs-full Basic Earnings Loss Per Share
BasicEarningsLossPerShare
-0.21
CY2021 ifrs-full Diluted Earnings Loss Per Share
DilutedEarningsLossPerShare
-0.21
CY2023 ifrs-full Disclosure Of Property Plant And Equipment Explanatory
DisclosureOfPropertyPlantAndEquipmentExplanatory
Property and Equipment<div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:29.809%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Cost</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Laboratory and Manufacturing Equipment</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Furniture and</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Fixtures</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Computer Equipment and</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Software</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Leasehold Improvements</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Construction in</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">process</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,733 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,452 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,329 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,485 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,116 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,115 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions, net of transfers</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">390 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">412 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,362 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,176 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(118)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(77)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(195)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(58)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(58)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassifications</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,336 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">58 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">137 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,067 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,598)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,341 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,510 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,419 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">23,964 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,803 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">43,037 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions, net of transfers</span></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">87 </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">87 </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals/Impairment</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,886)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(137)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,023)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,092)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(438)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(365)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,799)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,871)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(17,565)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassifications</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(18)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(18)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2023</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,363</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,072</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">917</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15,165</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">22,518</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:29.809%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Accumulated depreciation and impairment loss</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Laboratory and Manufacturing Equipment</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Furniture and</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Fixtures</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Computer Equipment and</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Software</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Leasehold Improvements</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Construction in</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">process</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,686)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(663)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,190)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,806)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(14,344)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,082)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(212)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(107)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,444)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,845)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">53 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">53 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,711)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(875)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,244)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,250)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(20,080)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation</span></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(892)</span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(162)</span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45)</span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,856)</span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,955)</span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">543 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">38 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">581 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,917 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">339 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">357 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,858 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,472 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2023</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,142)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(698)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(894)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(7,248)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(12,982)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:29.809%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Property and Equipment, net</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Laboratory and Manufacturing Equipment</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Furniture and</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Fixtures</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Computer Equipment and</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Software</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Leasehold Improvements</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Construction in</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">process</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,630 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">635 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">174 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,714 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,803 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,957 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2023</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,221</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">375</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">23</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7,917</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">9,536</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation of property and equipment is included in the general and administrative expenses and research and development expenses in the Consolidated Statement of Comprehensive Income/(Loss). The Group recorded depreciation expense of $2,955, $5,845 and $4,347 for the years ended December 31, 2023, 2022 and 2021, respectively.</span></div>
CY2023 ifrs-full Disclosure Of Detailed Information About Property Plant And Equipment Explanatory
DisclosureOfDetailedInformationAboutPropertyPlantAndEquipmentExplanatory
<div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:29.809%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Cost</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Laboratory and Manufacturing Equipment</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Furniture and</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Fixtures</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Computer Equipment and</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Software</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Leasehold Improvements</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Construction in</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">process</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,733 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,452 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,329 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,485 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,116 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,115 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions, net of transfers</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">390 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">412 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,362 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,176 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(118)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(77)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(195)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(58)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(58)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassifications</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,336 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">58 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">137 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,067 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,598)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,341 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,510 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,419 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">23,964 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,803 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">43,037 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions, net of transfers</span></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">87 </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">87 </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals/Impairment</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,886)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(137)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,023)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,092)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(438)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(365)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,799)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,871)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(17,565)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassifications</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(18)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(18)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2023</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,363</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,072</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">917</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15,165</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">22,518</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div>
CY2022Q4 ifrs-full Property Plant And Equipment
PropertyPlantAndEquipment
22957000 usd
CY2023Q4 ifrs-full Property Plant And Equipment
PropertyPlantAndEquipment
9536000 usd
CY2023 ifrs-full Depreciation Expense
DepreciationExpense
2955000 usd
CY2022 ifrs-full Depreciation Expense
DepreciationExpense
5845000 usd
CY2021 ifrs-full Depreciation Expense
DepreciationExpense
4347000 usd
CY2023 ifrs-full Disclosure Of Intangible Assets Explanatory
DisclosureOfIntangibleAssetsExplanatory
Intangible Assets<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Intangible assets consist of licenses of intellectual property acquired by the Group through various agreements with third parties and are recorded at the value of the consideration transferred. Information regarding the cost and accumulated amortization of intangible assets is as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:87.384%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Cost</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Licenses</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">990 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(163)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(21)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">831 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="border-top:0.5pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">200 </span></td><td style="border-top:0.5pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(105)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(19)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2023</span></div></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">906</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:87.384%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Accumulated amortization</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Licenses</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization</span></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2023</span></div></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:87.384%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Intangible assets, net</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Licenses</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">831 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2023</span></div></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">906</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Substantially all the intangible asset licenses represent in-process-research-and-development assets since they are still being developed and not ready for their intended use. As such, these assets are not amortized but tested for impairment annually. </span></div><div style="margin-bottom:5pt;margin-top:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2023, the Group wrote off two of its research intangible assets for which research was ceased in the amount of $105.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2023, Vedanta , Inc. was deconsolidated and as such, $19 net in intangible assets were derecognized.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31,2022, the Group wrote off one of its research intangible assets for which research was ceased in the amount of $163.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2022, Sonde Health, Inc. was deconsolidated and as such, $18 net intangible assets were derecognized.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group tested all intangible assets for impairment as of the balance sheet date and concluded that none of such assets were impaired. </span></div>The Group had negligible amortization expense for the years ended December 31, 2022 and 2021 and no amortization expense for the year ended December 31, 2023.
CY2023Q4 ifrs-full Retained Earnings
RetainedEarnings
83820000 usd
CY2022Q4 ifrs-full Retained Earnings
RetainedEarnings
149516000 usd
CY2023Q4 ifrs-full Equity Attributable To Owners Of Parent
EquityAttributableToOwnersOfParent
464066000 usd
CY2022Q4 ifrs-full Equity Attributable To Owners Of Parent
EquityAttributableToOwnersOfParent
542220000 usd
CY2023Q4 ifrs-full Noncontrolling Interests
NoncontrollingInterests
-5835000 usd
CY2022Q4 ifrs-full Noncontrolling Interests
NoncontrollingInterests
5369000 usd
CY2023Q4 ifrs-full Equity
Equity
458232000 usd
CY2022Q4 ifrs-full Equity
Equity
547589000 usd
CY2023Q4 ptv Number Of Votes Per Ordinary Share
NumberOfVotesPerOrdinaryShare
1 vote
CY2023 ifrs-full Disclosure Of Detailed Information About Intangible Assets Explanatory
DisclosureOfDetailedInformationAboutIntangibleAssetsExplanatory
Information regarding the cost and accumulated amortization of intangible assets is as follows:<div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:87.384%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Cost</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Licenses</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">990 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(163)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(21)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">831 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="border-top:0.5pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">200 </span></td><td style="border-top:0.5pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(105)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(19)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2023</span></div></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">906</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div>
CY2023 ptv Number Of Intangible Written Off Assets
NumberOfIntangibleWrittenOffAssets
2 asset
CY2022 ifrs-full Impairment Loss Recognised In Profit Or Loss Intangible Assets Other Than Goodwill
ImpairmentLossRecognisedInProfitOrLossIntangibleAssetsOtherThanGoodwill
163000 usd
CY2023 ifrs-full Disclosure Of Other Assets Explanatory
DisclosureOfOtherAssetsExplanatory
Other Financial Assets <div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other financial assets consist primarily of restricted cash reserved as collateral against a letter of credit with a bank that is issued for the benefit of a landlord in lieu of a security deposit for office space leased by the Group. The restricted cash was $1,628 and $2,124 as of December 31, 2023 and 2022, respectively.</span></div>
CY2023Q4 ifrs-full Restricted Cash And Cash Equivalents
RestrictedCashAndCashEquivalents
1628000 usd
CY2022Q4 ifrs-full Restricted Cash And Cash Equivalents
RestrictedCashAndCashEquivalents
2124000 usd
CY2023Q4 ifrs-full Par Value Per Share
ParValuePerShare
0.01
CY2022Q4 ifrs-full Par Value Per Share
ParValuePerShare
0.01
CY2023Q4 ifrs-full Number Of Shares Issued And Fully Paid
NumberOfSharesIssuedAndFullyPaid
271853731 shares
CY2022Q4 ifrs-full Number Of Shares Issued And Fully Paid
NumberOfSharesIssuedAndFullyPaid
278566306 shares
CY2023Q4 ifrs-full Issued Capital
IssuedCapital
5461000 usd
CY2022Q4 ifrs-full Issued Capital
IssuedCapital
5455000 usd
CY2023Q4 ifrs-full Share Premium
SharePremium
290262000 usd
CY2022Q4 ifrs-full Share Premium
SharePremium
289624000 usd
CY2023Q4 ifrs-full Treasury Shares
TreasuryShares
44626000 usd
CY2022Q4 ifrs-full Treasury Shares
TreasuryShares
26492000 usd
CY2023Q4 ifrs-full Merger Reserve
MergerReserve
138506000 usd
CY2022Q4 ifrs-full Merger Reserve
MergerReserve
138506000 usd
CY2023Q4 ifrs-full Reserve Of Exchange Differences On Translation
ReserveOfExchangeDifferencesOnTranslation
182000 usd
CY2022Q4 ifrs-full Reserve Of Exchange Differences On Translation
ReserveOfExchangeDifferencesOnTranslation
89000 usd
CY2023Q4 ifrs-full Other Reserves
OtherReserves
-9538000 usd
CY2022Q4 ifrs-full Other Reserves
OtherReserves
-14478000 usd
CY2023Q4 ifrs-full Number Of Shares Issued
NumberOfSharesIssued
289468159 shares
CY2022Q4 ptv Preferred Share Liability
PreferredShareLiability
27339000 usd
CY2023Q4 ptv Preferred Share Liability
PreferredShareLiability
169000 usd
CY2023Q4 ptv Minimum Liquidation Preference
MinimumLiquidationPreference
8621000 usd
CY2022Q4 ptv Minimum Liquidation Preference
MinimumLiquidationPreference
158189000 usd
CY2023 ifrs-full Disclosure Of Financial Liabilities Explanatory
DisclosureOfFinancialLiabilitiesExplanatory
Sale of Future Royalties Liability<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On March 4, 2011, the Group entered into a license agreement with Karuna Therapeutics, Inc. (“Karuna”) according to which the Group granted Karuna an exclusive license to research, develop and sell KarXT in exchange for a royalty on annual net sales, development and regulatory milestones and a fixed portion of sublicensing income, if any (hereinafter “License Agreement”).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On March 22, 2023, the Group signed an agreement with Royalty Pharma (hereinafter "Royalty Purchase Agreement"), according to which the Group sold Royalty Pharma a partial right to receive royalty payments made by Karuna in respect of net sales of KarXT, if and when received. According to the Royalty Purchase Agreement, all royalties due to the Group under the License Agreement will be paid to Royalty Pharma up until an annual threshold of $60,000, while all royalties above such annual threshold in a given year will be split 33% to Royalty Pharma and 67% to the Group. Under the terms of the Royalty Purchase Agreement, the Group received a non-refundable initial payment of $100,000 at the execution of the Royalty Purchase Agreement and is eligible to receive additional payments in the aggregate of up to an additional $400,000 based on the achievement of certain regulatory and commercial milestones.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group continues to hold the rights under the License Agreement and has a contractual obligation to deliver cash to Royalty Pharma for a portion of the royalties it receives. Therefore, the Group will continue to account for any royalties and regulatory milestones due to the Group under the License Agreement as revenue in its Consolidated Statement of Comprehensive Income/(Loss) and record the proceeds from the Royalty Purchase Agreement as a financial liability on its Consolidated Statement of Financial Position. In determining the appropriate accounting treatment for the Royalty Purchase Agreement, management applied significant judgement.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The acquisition of Karuna by Bristol Meyers Squibb (NYSE: BMY), which closed on March 18, 2024, had no impact on the Group's rights or obligations under the License Agreement or Royalty Purchase Agreement, each of which remains in full force and effect.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In order to determine the amortized cost of the sale of future royalties liability, management is required to estimate the total amount of future receipts from and payments to Royalty Pharma under the Royalty Purchase Agreement over the life of the agreement. The $100,000 liability, recorded at execution of the Royalty Purchase Agreement, will be accreted to the total of these receipts and payments as interest expense over the life of the Royalty Purchase Agreement. These estimates contain assumptions that impact both the amortized cost of the liability and the interest expense that will be recognized in future periods. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additional proceeds received from Royalty Pharma will increase the Group’s financial liability. As royalty payments are made to Royalty Pharma, the balance of the liability will be effectively repaid over the life of the Royalty Purchase Agreement. The estimated timing and amount of royalty payments to and proceeds from Royalty Pharma are likely to change over the life of the Royalty Purchase Agreement. A significant increase or decrease in estimated royalty payments, or a significant shift in the timing of cash flows, will materially impact the sale of future royalties liability, interest expense and the time period for repayment. The Group will periodically assess the expected payments to, or proceeds from, Royalty Pharma, and any such changes in amount or timing of cash flows will require the Group to re-calculate the amortized cost of the sale of future royalties liability as the present value of the estimated future cash flows from the Royalty Purchase Agreement that are discounted at the liability’s original effective interest rate. The adjustment is recognized immediately in profit or loss as income or expense. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following shows the activity in respect of the sale of future royalties liability:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:87.384%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sale of future royalties liability</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2023</span></div></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amounts received at closing</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non cash interest expense recognized</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,159 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2023</span></div></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">110,159</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div>
CY2023Q1 ptv Royalty Agreement Percentage Of Royalties Received Above Annual Threshold
RoyaltyAgreementPercentageOfRoyaltiesReceivedAboveAnnualThreshold
0.67
CY2023Q1 ptv Royalties Liabilities Initial Payment Received At Closing
RoyaltiesLiabilitiesInitialPaymentReceivedAtClosing
100000000 usd
CY2023Q1 ptv Royalties Liabilities Eligibility To Receive Additional Royalty Payment Amount
RoyaltiesLiabilitiesEligibilityToReceiveAdditionalRoyaltyPaymentAmount
400000000 usd
CY2023Q1 ptv Royalties Liabilities Initial Payment Received At Closing
RoyaltiesLiabilitiesInitialPaymentReceivedAtClosing
100000000 usd
CY2022Q4 ptv Non Current Liabilities Royalty Liabilities
NonCurrentLiabilitiesRoyaltyLiabilities
0 usd
CY2023 ptv Royalties Liabilities Initial Payment Received At Closing
RoyaltiesLiabilitiesInitialPaymentReceivedAtClosing
100000000 usd
CY2023 ptv Noncash Interest Expense Royalty Liability
NoncashInterestExpenseRoyaltyLiability
10159000 usd
CY2023Q4 ptv Non Current Liabilities Royalty Liabilities
NonCurrentLiabilitiesRoyaltyLiabilities
110159000 usd
CY2023 ifrs-full Disclosure Of Financial Instruments Explanatory
DisclosureOfFinancialInstrumentsExplanatory
Financial Instruments <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s financial instruments consist of financial assets in the form of notes, convertible notes and investment in shares, and financial liabilities, including preferred shares. Many of these financial instruments are presented at fair value, with changes in fair value recorded through profit and loss.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair Value Process</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For financial instruments measured at fair value under IFRS 9, the change in the fair value is reflected through profit and loss. Using the guidance in IFRS 13, the total business enterprise value and allocable equity of each entity being valued can be determined using a market backsolve approach through a recent arm’s length financing round (or a future probable arm's length transaction), market/asset probability-weighted expected return method ("PWERM") approach, discounted cash flow approach, or hybrid approaches. The approaches, in order of strongest fair value evidence, are detailed as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:21.021%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:76.779%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Valuation Method</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Description</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Market – Backsolve</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The market backsolve approach benchmarks the original issue price (OIP) of the company’s latest funding transaction as current value.</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Market/Asset – PWERM</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Under a PWERM, the company value is based upon the probability-weighted present value of expected future investment returns, considering each of the possible future outcomes available to the enterprise. Possible future outcomes can include IPO scenarios, potential SPAC transactions, merger and acquisition transactions as well as other similar exit transactions of the investee.</span></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Arial',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">I</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">ncome Based – DCF</span></div></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The income approach is used to estimate fair value based on the income streams, such as cash flows or earnings, that an asset or business can be expected to generate.</span></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">At each measurement date, investments held at fair value (that are not publicly traded) as well as the fair value of preferred share liabilities, including embedded conversion rights that are not bifurcated, were determined using the following allocation methods: option pricing model (“OPM”), PWERM, or hybrid allocation framework. The methods are detailed as follows:</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:21.021%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:76.779%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Allocation Method</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Description</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">OPM</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The OPM model treats preferred stock as call options on the enterprise’s equity value, with exercise prices based on the liquidation preferences of the preferred stock.</span><span style="color:#000000;font-family:'Arial',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PWERM</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Under a PWERM, share value is based upon the probability-weighted present value of expected future investment returns, considering each of the possible future outcomes available to the enterprise, as well as the rights of each share class. </span></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Hybrid</span></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The hybrid method is a combination of the PWERM and OPM. Under the hybrid method, multiple liquidity scenarios are weighted based on the probability of the scenario's occurrence, similar to the PWERM, while also utilizing the OPM to estimate the allocation of value in one or more of the scenarios. </span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Valuation policies and procedures are regularly monitored by the Group. Fair value measurements, including those categorized within Level 3, are prepared and reviewed for reasonableness and compliance with the fair value measurements guidance under IFRS accounting standards. The Group measures fair value using the following fair value hierarchy that reflects the significance of the inputs used in making the measurements:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:21.021%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:76.779%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Fair Value<br/>Hierarchy Level</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Description</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Level 1</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Inputs that are quoted market prices (unadjusted) in active markets for identical instruments.</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Level 2</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Inputs other than quoted prices included within Level 1 that are observable either directly (i.e. as prices) or indirectly (i.e. derived from prices). </span></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Level 3</span></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Inputs that are unobservable. This category includes all instruments for which the valuation technique includes inputs not based on observable data and the unobservable inputs have a significant effect on the instruments' valuation. </span></div></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Whilst the Group considers the methodologies and assumptions adopted in fair value measurements as supportable and reasonable, because of the inherent uncertainty of valuation, those estimated values may differ significantly from the values that would have been used had a ready market for the investment existed.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary Preferred Shares Liability and Subsidiary Convertible Notes</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the changes in the Group’s subsidiary preferred shares and convertible notes liabilities measured at fair value, which were categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary Preferred Shares<br/>$</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary Convertible<br/>Notes<br/>$</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">118,972 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25,000 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Value at issuance</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">37,610 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,215 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Conversion to subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25,797 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(25,797)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accrued interest - contractual</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">867 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,362)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">175 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">174,017 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,461 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Value at issuance</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">393 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accrued interest - contractual</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation - Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,853)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,403)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(130,825)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">502 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2022 and January 1, 2023</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,339 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,617)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation - Vedanta</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(24,554)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31, 2023</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">169</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The change in fair value of preferred shares and convertible notes liabilities are recorded in finance income/(costs) – fair value accounting in the Consolidated Statement of Comprehensive Income/(Loss).</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments Held at Fair Value</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Karuna, Vor and Akili Valuation</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna (Nasdaq: KRTX), Vor (Nasdaq: VOR), Akili (Nasdaq: AKLI) and additional immaterial investments are listed entities on an active exchange, and as such, the fair value as of December 31, 2023, was calculated utilizing the quoted common share price which is categorized as Level 1 in the fair value hierarchy. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Vedanta and Sonde</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2023, the Group accounts for the following investments under IFRS 9 as investments held at fair value with changes in fair value through the profit and loss: Sonde preferred A-2 and B shares and Vedanta convertible preferred shares (subsequent to the date of deconsolidation). The valuation of the aforementioned investments is categorized as Level 3 in the fair value hierarchy due to the use of significant unobservable inputs to value such assets. During the year ended December 31, 2023, the Group recorded such investments at fair value and recognized a loss of $7,298 for the change in fair value of the investments. In addition, the Group determined that the fair value of its investment in the Gelesis 2023 Warrants was $0 as Gelesis ceased operations in October 2023.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the changes in all the Group’s investments held at fair value, which were categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:5.25pt;text-align:justify"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:87.384%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">206,892 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash purchase of Vor preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassification of Vor from level 3 to level 1</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(33,365)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">65,505 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">239,533 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of Sonde</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,168 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis Earn-out Shares received in the SPAC exchange</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,214 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exchange of Gelesis preferred shares to Gelesis common shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(92,303)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassification of Akili to level 1 investment</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(128,764)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(31,253)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,593 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of Vedanta - new investment in Vedanta preferred shares</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20,456 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment in Gelesis 2023 Warrants</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,121 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on changes in fair value</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(9,299)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2023</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">24,872</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The change in fair value of investments held at fair value is recorded in gain/(loss) on investments held at fair value in the Consolidated Statement of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">At December 31, 2023, the Group’s material investments held at fair value categorized as Level 3 in the fair value hierarchy include the preferred shares of Sonde and Vedanta, with fair value of $10,408 and $14,153, respectively. The significant unobservable inputs used at December 31, 2023 in the fair value measurement of these investments and the sensitivity of the fair value measurements for these investments to changes to these significant unobservable inputs are summarized in the table below. </span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:47.536%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:16.021%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:16.021%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:16.022%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31, 2023</span></div></td><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Investment (Sonde) Measured through </span></div><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Market Backsolve &amp; OPM</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Unobservable Inputs</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Input Value </span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity Range</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Investment Fair Value Increase/(Decrease)</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity Value</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">53,242</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-5 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(464)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+5%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">463 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Time to Liquidity</span></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.00</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-6 Months</span></div></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">39 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+ 6 Months</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Volatility</span></div></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">60 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-10 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19</span></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+10%</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(35)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:47.536%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:16.021%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:16.021%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:16.022%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31, 2023</span></div></td><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Investment (Vedanta) Measured through Market Backsolve that Leverages a Monte Carlo Simulation</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Unobservable Inputs</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Input Value </span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity Range</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Investment Fair Value Increase/(Decrease)</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity Value</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">127,883</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-5 </span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,416)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+5%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,069 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Time to Liquidity</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.23</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">- 6 Months</span></div></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,907)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+ 6 Months</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,261 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Volatility</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">120 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-10 </span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(954)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-bottom:0.25pt solid #001544;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+10%</span></td><td colspan="2" style="border-bottom:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">474 </span></td><td style="border-bottom:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments in Notes from Associates</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2022, the investment in notes from associates was $16,501 and represents investments the Group made in convertible promissory notes of Gelesis. During the year ended December 31, 2023, the Group invested $10,729 in convertible promissory notes of Gelesis and $5,000 in a convertible note of Vedanta. The Group recorded a loss of $27,630 for the change in fair value of the notes from associates in the gain/(loss) on investments in notes from associates within the Consolidated Statement of Comprehensive Income/Loss. The loss was driven by a reduction in the fair value of the Gelesis convertible promissory notes of $27,230 as Gelesis filed for bankruptcy in October 2023 and a change in the fair value of the Vedanata convertible note of $400. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The convertible debt issued by Vedanta was valued using a market backsolve approach that leverages a Monte Carlo simulation. The significant unobservable inputs categorized as Level 3 in the fair value hierarchy used at December 31, 2023, in the fair value measurement of the convertible debt are the same as the inputs disclosed above for Vedanta preferred shares. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair Value Measurement and Classification</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of financial instruments by category as of December 31, 2023 and 2022:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:29.960%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.657%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.417%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="21" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Carrying Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="12" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Fair Value</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Financial Assets<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Financial Liabilities<br/>$</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 1<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 2<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 3<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total<br/>$</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Financial assets</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:5.52pt;font-weight:700;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">:</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Money Markets</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">156,705</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">156,705</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">156,705</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment in notes from associates</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,600</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,600</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,600</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">317,841</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">292,970</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">24,872</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">317,841</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total financial assets</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">479,146</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">449,675</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">29,472</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">479,146</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Financial liabilities:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">169</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">169</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">169</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based liability awards</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,782</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,782</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,782</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total financial liabilities</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,951</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,951</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,951</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Issued by a diverse group of corporations, largely consisting of financial institutions, virtually all of which are investment grade.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Included within cash and cash equivalents.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3. Excluded from the table above are short-term investments of $136,062 that are classified at amortized cost as of December 31, 2023. The cost of these short-term investments approximates current fair value. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has a number of financial instruments that are not measured at fair value in the Consolidated Statement of Financial Position. For these instruments the fair values are not materially different from their carrying amounts.</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:29.203%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="21" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></td></tr><tr><td colspan="3" style="padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Carrying Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="12" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Fair Value</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Assets<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Liabilities<br/>$</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 1<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 2<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 3<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial assets:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Money Markets</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">95,249 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">95,249 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">95,249 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term investments</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">200,229 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">200,229 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">200,229 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Note from associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,501 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,501 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,501 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">251,892 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">239,299 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,593 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">251,892 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,867 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,867 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,867 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total financial assets</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">575,738 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">534,777 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,867 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">29,094 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">575,738 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial liabilities:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary warrant liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,339 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,339 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,339 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,345 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,097 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">248 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,345 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based liability awards</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,932 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,396 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,537 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,932 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total financial liabilities</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35,664 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,396 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,097 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">29,171 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35,664 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Issued by a diverse group of corporations, largely consisting of financial institutions, virtually all of which are investment grade.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Included within cash and cash equivalents.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3 Outstanding receivables are owed primarily by government agencies and large corporations, virtually all of which are investment grade.</span></div>
CY2023 ifrs-full Disclosure Of Sensitivity Analysis Of Fair Value Measurement To Changes In Unobservable Inputs Liabilities Explanatory
DisclosureOfSensitivityAnalysisOfFairValueMeasurementToChangesInUnobservableInputsLiabilitiesExplanatory
The significant unobservable inputs used at December 31, 2023 in the fair value measurement of these investments and the sensitivity of the fair value measurements for these investments to changes to these significant unobservable inputs are summarized in the table below. <div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:47.536%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:16.021%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:16.021%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:16.022%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31, 2023</span></div></td><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Investment (Sonde) Measured through </span></div><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Market Backsolve &amp; OPM</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Unobservable Inputs</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Input Value </span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity Range</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Investment Fair Value Increase/(Decrease)</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity Value</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">53,242</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-5 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(464)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+5%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">463 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Time to Liquidity</span></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.00</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-6 Months</span></div></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">39 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+ 6 Months</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Volatility</span></div></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">60 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-10 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19</span></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+10%</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 35 Light',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(35)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:47.536%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:16.021%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:16.021%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:16.022%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31, 2023</span></div></td><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Investment (Vedanta) Measured through Market Backsolve that Leverages a Monte Carlo Simulation</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Unobservable Inputs</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Input Value </span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity Range</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Investment Fair Value Increase/(Decrease)</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity Value</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">127,883</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-5 </span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,416)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+5%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,069 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Time to Liquidity</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.23</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">- 6 Months</span></div></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,907)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+ 6 Months</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,261 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Volatility</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">120 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">-10 </span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(954)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-bottom:0.25pt solid #001544;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+10%</span></td><td colspan="2" style="border-bottom:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">474 </span></td><td style="border-bottom:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr></table></div>
CY2023 ptv Gain Loss On Investment In Notes Receivable From Associates
GainLossOnInvestmentInNotesReceivableFromAssociates
-27630000 usd
CY2023 ifrs-full Disclosure Of Fair Value Measurement Explanatory
DisclosureOfFairValueMeasurementExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of financial instruments by category as of December 31, 2023 and 2022:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:29.960%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.657%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.417%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="21" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Carrying Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="12" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Fair Value</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Financial Assets<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Financial Liabilities<br/>$</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 1<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 2<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 3<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total<br/>$</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Financial assets</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:5.52pt;font-weight:700;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">:</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Money Markets</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">156,705</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">156,705</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">156,705</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment in notes from associates</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,600</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,600</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,600</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">317,841</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">292,970</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">24,872</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">317,841</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total financial assets</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">479,146</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">449,675</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">29,472</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">479,146</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Financial liabilities:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">169</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">169</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">169</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based liability awards</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,782</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,782</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,782</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total financial liabilities</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,951</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,951</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,951</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Issued by a diverse group of corporations, largely consisting of financial institutions, virtually all of which are investment grade.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Included within cash and cash equivalents.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3. Excluded from the table above are short-term investments of $136,062 that are classified at amortized cost as of December 31, 2023. The cost of these short-term investments approximates current fair value. </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:29.203%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="21" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></td></tr><tr><td colspan="3" style="padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Carrying Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="12" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Fair Value</span></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Assets<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Liabilities<br/>$</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 1<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 2<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 3<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial assets:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Money Markets</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">95,249 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">95,249 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">95,249 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term investments</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">200,229 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">200,229 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">200,229 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Note from associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,501 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,501 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,501 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">251,892 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">239,299 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12,593 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">251,892 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,867 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,867 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,867 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total financial assets</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">575,738 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">534,777 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,867 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">29,094 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">575,738 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial liabilities:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary warrant liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,339 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,339 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,339 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,345 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,097 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">248 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,345 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based liability awards</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,932 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,396 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,537 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,932 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total financial liabilities</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35,664 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,396 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,097 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">29,171 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35,664 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Issued by a diverse group of corporations, largely consisting of financial institutions, virtually all of which are investment grade.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Included within cash and cash equivalents.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3 Outstanding receivables are owed primarily by government agencies and large corporations, virtually all of which are investment grade.</span></div>
CY2023Q4 ifrs-full Financial Assets At Fair Value
FinancialAssetsAtFairValue
479146000 usd
CY2023Q4 ifrs-full Financial Liabilities At Fair Value
FinancialLiabilitiesAtFairValue
4951000 usd
CY2022Q4 ifrs-full Financial Assets At Fair Value
FinancialAssetsAtFairValue
575738000 usd
CY2022Q4 ifrs-full Financial Liabilities At Fair Value
FinancialLiabilitiesAtFairValue
35664000 usd
CY2023Q4 ifrs-full Current Financial Liabilities
CurrentFinancialLiabilities
3699000 usd
CY2022Q4 ifrs-full Current Financial Liabilities
CurrentFinancialLiabilities
2345000 usd
CY2023 ifrs-full Disclosure Of Noncontrolling Interests Explanatory
DisclosureOfNoncontrollingInterestsExplanatory
Non-Controlling Interest<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2023, non-controlling interests include Entrega and Follica. Ownership interests of the non-controlling interests in these entities as of December 31, 2023 were 11.7 percent, and 19.9 percent, respectively. As of December 31, 2022, non-controlling interests include Entrega, Follica, and Vedanta. Ownership interests of the non-controlling interests in these entities were 11.7 percent , 19.9 percent, and 12.2 percent, respectively. As of December 31, 2021, non-controlling interests include Entrega, Follica, Sonde, and Vedanta. Ownership interests of the non-controlling interests in these entities were 11.7 percent, 19.9 percent, 6.2 percent and 3.7 percent, respectively. During the year ended December 31, 2023, Vedanta Biosciences, Inc was deconsolidated. During the year ended December 31, 2022, Sonde Health, Inc was deconsolidated. See Note 5. Investments Held at Fair Value. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-controlling interests include the amounts recorded for subsidiary stock options.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On June 11, 2021, the Group acquired the remaining 17.1 percent of the minority non-controlling interests of Alivio (after exercise of all in the money stock options) increasing its ownership to 100.0 percent of Alivio. The consideration for such non-controlling interests amounted to $1,224, to be paid in three equal installments, with the first installment of $408 paid at the effective date of the transaction and two additional installments to be paid upon the occurrence of certain contingent events. The Group recorded a contingent consideration liability of $560 at fair value for the two additional installments, resulting in a total acquisition cost of $968. The excess of the consideration paid over the book value of the non-controlling interest of approximately $9,636 was recorded directly as a charge to shareholders’ equity. The second installment of $408 was paid in July 2021, upon the occurrence of the contingent event specified in the agreement. The contingent consideration liability was adjusted to fair value at the end of each reporting period with changes in fair value recorded in earnings. Changes in fair value of the aforementioned contingent consideration liability were not material. As of December 31, 2022, the remaining contingent liability was reduced to zero as the second contingent event did not occur.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On December 1, 2021, option holders in Entrega exercised options into shares of common stock, increasing the NCI interest held from 0.2 percent to 11.7 percent. During 2021, option holders in Vedanta exercised options and increased the NCI interest to 3.7 percent. The exercise of the options resulted in an increase in the NCI share in Entrega and Vedanta shareholder's deficit of $5,887. The amount together with the consideration paid by NCI ($101) amounted to $5,988 and was recorded as a gain directly in shareholders' equity.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On February 15, 2022, option holders in Vedanta exercised options into shares of common stock, increasing the NCI interest held from 3.7 percent to 12.2 percent. The exercise of the options resulted in an increase in the NCI share in Vedanta shareholder's deficit of $15,171. The amount together with the consideration paid by NCI ($7) amounted to $15,171 and was recorded as a gain directly in shareholders' equity.</span></div>
CY2021Q2 ifrs-full Contingent Consideration Recognised As Of Acquisition Date
ContingentConsiderationRecognisedAsOfAcquisitionDate
560000 usd
CY2021Q2 ifrs-full Consideration Paid Received
ConsiderationPaidReceived
9636000 usd
CY2023 ifrs-full Disclosure Of Trade And Other Payables Explanatory
DisclosureOfTradeAndOtherPayablesExplanatory
Trade and Other Payables <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Information regarding Trade and other payables was as follows: </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31,</span></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="display:none"></td></tr><tr style="height:9pt"><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade payables</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,637</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">26,504 </span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accrued expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28,187</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24,518 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income tax payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Liability for share-based awards</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,281</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,805 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,957 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total trade and other payables</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">44,107</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">54,840 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr></table></div>
CY2023Q4 ifrs-full Trade And Other Current Payables To Trade Suppliers
TradeAndOtherCurrentPayablesToTradeSuppliers
14637000 usd
CY2022Q4 ifrs-full Trade And Other Current Payables To Trade Suppliers
TradeAndOtherCurrentPayablesToTradeSuppliers
26504000 usd
CY2023Q4 ifrs-full Accruals Classified As Current
AccrualsClassifiedAsCurrent
28187000 usd
CY2022Q4 ifrs-full Accruals Classified As Current
AccrualsClassifiedAsCurrent
24518000 usd
CY2023Q4 ptv Income Tax Payable
IncomeTaxPayable
0 usd
CY2022Q4 ptv Income Tax Payable
IncomeTaxPayable
57000 usd
CY2023Q4 ptv Other Payables Liability Settled Share Based Awards
OtherPayablesLiabilitySettledShareBasedAwards
1281000 usd
CY2022Q4 ptv Other Payables Liability Settled Share Based Awards
OtherPayablesLiabilitySettledShareBasedAwards
1805000 usd
CY2023Q4 ifrs-full Other Current Payables
OtherCurrentPayables
3000 usd
CY2022Q4 ifrs-full Other Current Payables
OtherCurrentPayables
1957000 usd
CY2023Q4 ifrs-full Trade And Other Current Payables
TradeAndOtherCurrentPayables
44107000 usd
CY2022Q4 ifrs-full Trade And Other Current Payables
TradeAndOtherCurrentPayables
54840000 usd
CY2023 ifrs-full Disclosure Of Borrowings Explanatory
DisclosureOfBorrowingsExplanatory
Long-term loan<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In September 2020, Vedanta entered into a $15,000 loan and security agreement with Oxford Finance LLC. The loan is secured by Vedanta's assets, including equipment, inventory and intellectual property. The loan bears a floating interest rate of 7.7 percent plus the greater of (i) 30 day U.S. Dollar LIBOR reported in the Wall Street Journal or (ii) 0.17 percent. The loan matures September 2025 and requires interest-only payments prior to 2023. The loan also carries a final fee upon full repayment of 7.0 percent of the original principal, or $1,050. As part of the loan agreement, Vedanta also issued Oxford Finance LLC 12,886 Series C-2 preferred share warrants with an exercise price of $23.28 per share, expiring September 2030. The outstanding loan balance totaled approximately $15,400 as of December 31, 2022. On March 1, 2023, the Group derecognized the loan in connection with Vedanta's deconsolidation. Refer to Note 5. Investments Held at Fair Value. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes long-term loan activity for the years ended December 31, 2023 and 2022:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Long-term loan</span></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="9" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1,</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15,400</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,118 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accrued interest</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">363</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,755 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest paid</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(300)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,436)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(17)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(38)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(15,446)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31,</span></div></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,400 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The long-term loan is presented as follows in the Statement of Financial Position as of December 31, 2023 and 2022: </span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:middle"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Long-term loan</span></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="9" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current portion of long-term loan</span></div></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,156 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term loan</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,244 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total Long-term loan</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,400 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div>
CY2022Q4 ifrs-full Borrowings
Borrowings
15400000 usd
CY2021Q4 ifrs-full Borrowings
Borrowings
15118000 usd
CY2023 ptv Borrowings Accrued Interest
BorrowingsAccruedInterest
363000 usd
CY2022 ptv Borrowings Accrued Interest
BorrowingsAccruedInterest
1755000 usd
CY2023 ptv Borrowings Interest Paid
BorrowingsInterestPaid
300000 usd
CY2022 ptv Borrowings Interest Paid
BorrowingsInterestPaid
1436000 usd
CY2023 ptv Borrowings Other
BorrowingsOther
17000 usd
CY2022 ptv Borrowings Other
BorrowingsOther
38000 usd
CY2023 ptv Borrowings Deconsolidation Of Subsidiary
BorrowingsDeconsolidationOfSubsidiary
15446000 usd
CY2022 ptv Borrowings Deconsolidation Of Subsidiary
BorrowingsDeconsolidationOfSubsidiary
0 usd
CY2023Q4 ifrs-full Borrowings
Borrowings
0 usd
CY2022Q4 ifrs-full Borrowings
Borrowings
15400000 usd
CY2023 ifrs-full Disclosure Of Detailed Information About Borrowings Explanatory
DisclosureOfDetailedInformationAboutBorrowingsExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The long-term loan is presented as follows in the Statement of Financial Position as of December 31, 2023 and 2022: </span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:middle"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Long-term loan</span></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="9" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current portion of long-term loan</span></div></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,156 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term loan</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,244 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total Long-term loan</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,400 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div>
CY2023Q4 ifrs-full Current Portion Of Longterm Borrowings
CurrentPortionOfLongtermBorrowings
0 usd
CY2022Q4 ifrs-full Current Portion Of Longterm Borrowings
CurrentPortionOfLongtermBorrowings
5156000 usd
CY2023Q4 ifrs-full Longterm Borrowings
LongtermBorrowings
0 usd
CY2022Q4 ifrs-full Longterm Borrowings
LongtermBorrowings
10244000 usd
CY2023Q4 ifrs-full Borrowings
Borrowings
0 usd
CY2022Q4 ifrs-full Borrowings
Borrowings
15400000 usd
CY2023 ifrs-full Disclosure Of Leases Explanatory
DisclosureOfLeasesExplanatory
Leases and subleases<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The activity related to the Group’s right of use asset and lease liability for the years ended December 31, 2023 and 2022 is as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Right of use asset, net</span></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="9" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1,</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,281</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,166 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">163 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,979)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,047)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidated</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,477)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31,</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">9,825</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,281 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total lease liability</span></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="9" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1,</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">29,128</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">32,990 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">163 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash paid for rent - principal - financing cash flow</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,338)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,025)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash paid for rent - interest </span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,544)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,982)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,544</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,982 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidated</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,146)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31,</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,644</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">29,128 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation of the right-of-use assets, which virtually all consist of leased real estate, is included in the general and administrative expenses and research and development expenses line items in the Statement of Comprehensive Income/(Loss). The Group recorded depreciation expense of $1,979, $3,047 and $2,938 for the years ended December 31, 2023, 2022 and 2021, respectively.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table details the short-term and long-term portion of the lease liability as of December 31, 2023 and 2022:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:middle"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total lease liability</span></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="9" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term portion of lease liability</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,394</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,972 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term portion of lease liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">18,250</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24,155 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total lease liability</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,644</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">29,128 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table details the future maturities of the lease liability, showing the undiscounted lease payments to be paid after the reporting date:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:87.384%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="6" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Less than one year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,689</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">One to two years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,644</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Two to three years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,419</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Three to four years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,551</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Four to five years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,687</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">More than five years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,796</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total undiscounted lease maturities</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,785</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,141</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total lease liability</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,644</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2019, the Group entered into a lease agreement for certain premises consisting of 50,858 rentable square feet of space located at 6 Tide Street, Boston, Massachusetts. The lease commenced on April 26, 2019 for an initial term consisting of ten years and three months, and there is an option to extend the lease for two consecutive periods of five years each. The Group assessed at the lease commencement date whether it was reasonably certain to exercise the extension options, and deemed such options were not reasonably certain to be exercised. The Group will reassess whether it is reasonably certain to exercise the options only if there is a significant event or significant change in circumstances within its control. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On June 26, 2019, the Group executed a sublease agreement with Gelesis. The lease is for 9,446 rentable square feet located on the sixth floor of the Group’s former office at 501 Boylston Street, Boston, Massachusetts. The sublease was set to expire on August 31, 2025, and was determined to be a finance lease. Gelesis ceased operations and filed for bankruptcy on October 30, 2023. As a result, the Group wrote off its receivable in the lease of $1,266 in 2023. </span></div>On January 23, 2023, the Group executed a sublease agreement with Allonnia, LLC (“Allonnia”). The sublease is for approximately 11,000 rentable square feet located on the third floor of the 6 Tide Street building where the Group’s offices are currently located. Allonnia obtained possession of the premises on February 17, 2023 with a rent commencement date of May 17, 2023. The lease term is two years from the rent commencement date, and Allonnia has the option to extend the sublease for an additional year at the same terms. The annual lease fee is $1,111 per year. The sublease was determined to be an operating lease, and as such, the total lease payments under the sublease agreement are recognized over the lease term on a straight-line basis. In February 2024, Allonnia exercised the option and extended the lease term through May 31, 2026<div style="margin-bottom:5pt;margin-top:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Rental income recognized by the Group during the year ended December 31, 2023 was $781 which was included in the other income/(expense) line item in the Consolidated Statement of Comprehensive Income/(Loss). In the year ended December 31, 2022, the Group did not recognize any rental income.</span></div>
CY2023 ifrs-full Disclosure Of Quantitative Information About Rightofuse Assets Explanatory
DisclosureOfQuantitativeInformationAboutRightofuseAssetsExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The activity related to the Group’s right of use asset and lease liability for the years ended December 31, 2023 and 2022 is as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Right of use asset, net</span></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="9" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1,</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,281</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,166 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">163 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,979)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,047)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidated</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,477)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31,</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">9,825</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,281 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div>
CY2022Q4 ifrs-full Rightofuse Assets
RightofuseAssets
14281000 usd
CY2021Q4 ifrs-full Rightofuse Assets
RightofuseAssets
17166000 usd
CY2021Q4 ifrs-full Rightofuse Assets
RightofuseAssets
17166000 usd
CY2023 ifrs-full Additions To Rightofuse Assets
AdditionsToRightofuseAssets
0 usd
CY2022 ifrs-full Additions To Rightofuse Assets
AdditionsToRightofuseAssets
163000 usd
CY2023 ifrs-full Depreciation Rightofuse Assets
DepreciationRightofuseAssets
1979000 usd
CY2022 ifrs-full Depreciation Rightofuse Assets
DepreciationRightofuseAssets
3047000 usd
CY2023 ptv Deconsolidation Right Of Use Assets
DeconsolidationRightOfUseAssets
2477000 usd
CY2022 ptv Deconsolidation Right Of Use Assets
DeconsolidationRightOfUseAssets
0 usd
CY2023Q4 ifrs-full Rightofuse Assets
RightofuseAssets
9825000 usd
CY2022Q4 ifrs-full Rightofuse Assets
RightofuseAssets
14281000 usd
CY2022Q4 ifrs-full Lease Liabilities
LeaseLiabilities
29128000 usd
CY2021Q4 ifrs-full Lease Liabilities
LeaseLiabilities
32990000 usd
CY2023 ptv Additions Lease Liabilities
AdditionsLeaseLiabilities
0 usd
CY2022 ptv Additions Lease Liabilities
AdditionsLeaseLiabilities
163000 usd
CY2023 ifrs-full Payments Of Lease Liabilities Classified As Financing Activities
PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities
3338000 usd
CY2022 ifrs-full Payments Of Lease Liabilities Classified As Financing Activities
PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities
4025000 usd
CY2023 ifrs-full Cash Outflow For Leases
CashOutflowForLeases
1544000 usd
CY2022 ifrs-full Cash Outflow For Leases
CashOutflowForLeases
1982000 usd
CY2023 ifrs-full Interest Expense On Lease Liabilities
InterestExpenseOnLeaseLiabilities
1544000 usd
CY2022 ifrs-full Interest Expense On Lease Liabilities
InterestExpenseOnLeaseLiabilities
1982000 usd
CY2023 ptv Deconsolidated Lease Liabilities
DeconsolidatedLeaseLiabilities
4146000 usd
CY2022 ptv Deconsolidated Lease Liabilities
DeconsolidatedLeaseLiabilities
0 usd
CY2023Q4 ifrs-full Lease Liabilities
LeaseLiabilities
21644000 usd
CY2022Q4 ifrs-full Lease Liabilities
LeaseLiabilities
29128000 usd
CY2023 ifrs-full Depreciation Rightofuse Assets
DepreciationRightofuseAssets
1979000 usd
CY2022 ifrs-full Depreciation Rightofuse Assets
DepreciationRightofuseAssets
3047000 usd
CY2021 ifrs-full Depreciation Rightofuse Assets
DepreciationRightofuseAssets
2938000 usd
CY2023Q4 ifrs-full Current Lease Liabilities
CurrentLeaseLiabilities
3394000 usd
CY2022Q4 ifrs-full Current Lease Liabilities
CurrentLeaseLiabilities
4972000 usd
CY2023Q4 ifrs-full Noncurrent Lease Liabilities
NoncurrentLeaseLiabilities
18250000 usd
CY2022Q4 ifrs-full Noncurrent Lease Liabilities
NoncurrentLeaseLiabilities
24155000 usd
CY2023Q4 ifrs-full Lease Liabilities
LeaseLiabilities
21644000 usd
CY2022Q4 ifrs-full Lease Liabilities
LeaseLiabilities
29128000 usd
CY2023 ifrs-full Disclosure Of Maturity Analysis Of Operating Lease Payments Explanatory
DisclosureOfMaturityAnalysisOfOperatingLeasePaymentsExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table details the future maturities of the lease liability, showing the undiscounted lease payments to be paid after the reporting date:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:87.384%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="6" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Less than one year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,689</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">One to two years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,644</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Two to three years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,419</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Three to four years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,551</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Four to five years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,687</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">More than five years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,796</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total undiscounted lease maturities</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,785</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,141</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total lease liability</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21,644</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div>
CY2023Q4 ifrs-full Undiscounted Operating Lease Payments To Be Received
UndiscountedOperatingLeasePaymentsToBeReceived
25785000 usd
CY2023 ptv Interest On Undiscounted Lease Payments
InterestOnUndiscountedLeasePayments
4141000 usd
CY2023Q4 ifrs-full Lease Liabilities
LeaseLiabilities
21644000 usd
CY2023 ifrs-full Rental Income
RentalIncome
781000 usd
CY2022 ifrs-full Rental Income
RentalIncome
0 usd
CY2023 ifrs-full Disclosure Of Financial Risk Management Explanatory
DisclosureOfFinancialRiskManagementExplanatory
Capital and Financial Risk Management <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Capital Risk Management</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group's capital and financial risk management policy is to maintain a strong capital base to support its strategic priorities, maintain investor, creditor and market confidence as well as sustain the future development of the business. The Group’s objectives when managing capital are to safeguard its ability to continue as a going concern, to provide returns for shareholders and benefits for other stakeholders, and to maintain an optimal capital structure to reduce the cost of capital. To maintain or adjust the capital structure, the Group may issue new shares or incur new debt. The Group has no material externally imposed capital requirements. The Group’s share capital is set out in Note 15. Equity.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Management continuously monitors the level of capital deployed and available for deployment in the Wholly-Owned Programs segment and at Founded Entities. The Directors seek to maintain a balance between the higher returns that might be possible with higher levels of deployed capital and the advantages and security afforded by a sound capital position.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s Directors have overall responsibility for the establishment and oversight of the Group's capital and risk management framework. The Group is exposed to certain risks through its normal course of operations. The Group’s main objective in using financial instruments is to promote the development and commercialization of intellectual property through the raising and investing of funds for this purpose. The nature, amount and timing of investments are determined by planned future investment activity. Due to the nature of activities and with the aim to maintain the investors’ funds as secure and protected, the Group’s policy is to hold any excess funds in highly liquid and readily available financial instruments and maintain minimal exposure to other financial risks.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has exposure to the following risks arising from financial instruments:</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Credit Risk</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Credit risk is the risk of financial loss to the Group if a customer or counterparty to a financial instrument fails to meet its contractual obligations. Financial instruments that potentially subject the Group to concentrations of credit risk consist principally of cash and cash equivalents, short-term investments, and trade and other receivables. The Group held the following balances (not including the income tax receivable resulting from overpayment of income taxes as of December 31, 2022. See Note 27. Taxation):</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="display:none"></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and cash equivalents</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">191,081</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">149,866 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">136,062</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">200,229 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,376</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,867 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">329,518</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">361,961 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group invests its excess cash in U.S. Treasury Bills (presented as short-term investments), and money market accounts, which the Group believes are of high credit quality. Further, the Group's cash and cash equivalents and short-term investments are held at diverse, investment-grade financial institutions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group assesses the credit quality of customers on an ongoing basis. The credit quality of financial assets is assessed by historical and recent payment history, counterparty financial position, and reference to credit ratings (if available) or to historical information about counterparty default rates. The Group does not have expected credit losses due to the high credit quality or healthy financial conditions of these counterparties. As of December 31, 2023 and 2022, none of the trade and other receivables were impaired.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Liquidity Risk</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Liquidity risk is the risk that the Group will encounter difficulty in meeting the obligations associated with its financial liabilities that are settled by delivering cash or another financial asset. The Group actively manages its liquidity risk by closely monitoring the maturity of its financial assets and liabilities and projected cash flows from operations, under both normal and stressed conditions, without incurring unacceptable losses or risking damage to the Group’s reputation. Due to the nature of these financial liabilities, the funds are available on demand to provide optimal financial flexibility.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The table below summarizes the maturity profile of the Group’s financial liabilities, including subsidiary preferred shares that have customary liquidation preferences, as of December 31, 2023 and 2022, based on contractual undiscounted payments:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:41.324%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></td></tr><tr style="height:26pt"><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Carrying Amount<br/>$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Within Three Months<br/>$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Three to Twelve Months<br/>$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">One to Five Years<br/>$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total<br/>$ (*)</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></div></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,699</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,699</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,699</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other payables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">44,107</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">44,107</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">44,107</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares (Note 16)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">169</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">169</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">169</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47,975</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47,975</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47,975</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:41.324%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></td></tr><tr style="height:26pt"><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Carrying Amount<br/>$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Within Three Months<br/>$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Three to Twelve Months<br/>$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">One to Five Years<br/>$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$ (*)</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term loan</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,400 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,838 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,281 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,413 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,531 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,345 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,345 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,345 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other payables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">54,840 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">54,840 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">54,840 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrants</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares (Note 16)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,339 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,339 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,339 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99,971 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86,409 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,281 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,413 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">103,103 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Redeemable only upon a liquidation or deemed liquidation event, as defined in the applicable shareholder documents.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Warrants issued by subsidiaries to third parties to purchase preferred shares.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">*    Does not include payments in respect of lease obligations. For the contractual future payments related to lease obligation</span><span style="background-color:#ffffff;color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">s, see Note 23. Leases and subleases.</span></div><div style="margin-bottom:2pt;padding-left:11.34pt;text-indent:-11.34pt"><span><br/></span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest Rate Sensitivity </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2023, the Group had cash and cash equivalents of $191,081, and short-term investments of $136,062. The Group's exposure to interest rate sensitivity is impacted by changes in the underlying U.K. and U.S. bank interest rates. The Group has not entered into investments for trading or speculative purposes. Due to the conservative nature of the Group's investment portfolio, which is predicated on capital preservation and investments in short duration, high-quality U.S. Treasury Bills and related money market accounts, a change in interest rates would not have a material effect on the fair market value of the Group's portfolio, and therefore, the Group does not expect operating results or cash flows to be significantly affected by changes in market interest rates.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Controlled Founded Entity Investments</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group maintains investments in certain Controlled Founded Entities. The Group’s investments in Controlled Founded Entities are eliminated as intercompany transactions upon financial consolidation. The Group is, however, exposed to a preferred share liability owing to the terms of existing preferred shares and the ownership of Controlled Founded Entities preferred shares by third parties. As discussed in Note 16. Subsidiary Preferred Shares, certain of the Group’s subsidiaries have issued preferred shares that include the right to receive a payment in the event of any voluntary or involuntary liquidation, dissolution or winding up of a subsidiary, including in the event of "deemed liquidation" as defined in the incorporation documents of the entities, which shall be paid out of the assets of the subsidiary available for distribution to shareholders, and before any payment shall be made to holders of ordinary shares. The liability of preferred shares is maintained at fair value through the profit and loss. The Group’s cash position supports the business activities of the Controlled Founded Entities. Accordingly, the Group views exposure to the third party preferred share liability as low.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidated Founded Entity Investments</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group maintains certain debt or equity holdings in Founded Entities that are deconsolidated. These holdings are deemed either as investments and accounted for as investments held at fair value, or as associates and accounted for under the equity method. The Group's exposure to investments held at fair value is $317,841 as of December 31, 2023, and the Group may or may not be able to realize the value in the future. Accordingly, the Group views the risk as high. The Group’s exposure to investments in associates is limited to the carrying amount of the investment in an associate. The Group is not exposed to further contractual obligations or contingent liabilities beyond the value of the initial investments. Accordingly, the Group does not view this as a high risk. As of December 31, 2023, Sonde is the only associate, and the carrying amount of the investment as associate is $3,185.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity Price Risk</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2023, the Group held 886,885 common shares of Karuna, 2,671,800 common shares of Vor and 12,527,477 common shares of Akili. The fair value of these investments in Karuna, Vor and Akili was $292,831, of which approximately 96% is related to the Karuna common shares. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The investments in Karuna, Vor and Akili are exposed to fluctuations in the market price of these common shares. The effect of a 10.0 percent adverse change in the market price of Karuna, Vor and Akili common shares would cause a loss of approximately $29,283 to be recognized as a component of other income (expense) in the Consolidated Statement of Comprehensive Income/(Loss). However, the Group views exposure to equity price risk as low due to the definitive merger agreement Karuna entered into with Bristol Myers Squibb "BMS") in December 2023 under which Karuna common shares were acquired by Bristol Myers Squibb for $330 per share in March 2024. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Foreign Exchange Risk</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group maintains consolidated financial statements in the Group's functional currency, which is the U.S. dollar. Monetary assets and liabilities denominated in currencies other than the functional currency are translated into the functional currency at exchange rates prevailing at the balance sheet dates. Non-monetary assets and liabilities denominated in foreign currencies are translated into the functional currency at the exchange rates prevailing at the date of the transaction. Exchange gains or losses arising from foreign currency transactions are included in the determination of net income (loss) for the respective periods. Such foreign currency gains or losses were not material for all reported periods. </span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group does not currently engage in currency hedging activities since its foreign currency risk is limited, but the Group may begin to do so in the future if and when its foreign currency risk exposure changes.</span></div>
CY2023 ifrs-full Disclosure Of Credit Risk Explanatory
DisclosureOfCreditRiskExplanatory
The Group held the following balances (not including the income tax receivable resulting from overpayment of income taxes as of December 31, 2022. See Note 27. Taxation):<div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="display:none"></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and cash equivalents</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">191,081</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">149,866 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">136,062</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">200,229 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,376</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,867 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">329,518</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">361,961 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr></table></div>
CY2023Q4 ifrs-full Cash And Cash Equivalents
CashAndCashEquivalents
191081000 usd
CY2022Q4 ifrs-full Cash And Cash Equivalents
CashAndCashEquivalents
149866000 usd
CY2023Q4 ptv Short Term Investment
ShortTermInvestment
136062000 usd
CY2022Q4 ptv Short Term Investment
ShortTermInvestment
200229000 usd
CY2023Q4 ifrs-full Current Trade Receivables
CurrentTradeReceivables
2376000 usd
CY2022Q4 ifrs-full Current Trade Receivables
CurrentTradeReceivables
11867000 usd
CY2023Q4 ifrs-full Credit Exposure
CreditExposure
329518000 usd
CY2022Q4 ifrs-full Credit Exposure
CreditExposure
361961000 usd
CY2023 ifrs-full Disclosure Of Liquidity Risk Explanatory
DisclosureOfLiquidityRiskExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The table below summarizes the maturity profile of the Group’s financial liabilities, including subsidiary preferred shares that have customary liquidation preferences, as of December 31, 2023 and 2022, based on contractual undiscounted payments:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:41.324%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></td></tr><tr style="height:26pt"><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Carrying Amount<br/>$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Within Three Months<br/>$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Three to Twelve Months<br/>$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">One to Five Years<br/>$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total<br/>$ (*)</span></div></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></div></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,699</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,699</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,699</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other payables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">44,107</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">44,107</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">44,107</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares (Note 16)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">169</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">169</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">169</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47,975</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47,975</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47,975</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:41.324%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></td></tr><tr style="height:26pt"><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Carrying Amount<br/>$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Within Three Months<br/>$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Three to Twelve Months<br/>$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">One to Five Years<br/>$</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$ (*)</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term loan</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,400 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,838 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,281 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,413 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,531 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,345 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,345 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,345 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other payables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">54,840 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">54,840 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">54,840 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrants</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares (Note 16)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,339 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,339 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">27,339 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99,971 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86,409 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,281 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,413 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">103,103 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Redeemable only upon a liquidation or deemed liquidation event, as defined in the applicable shareholder documents.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Warrants issued by subsidiaries to third parties to purchase preferred shares.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">*    Does not include payments in respect of lease obligations. For the contractual future payments related to lease obligation</span><span style="background-color:#ffffff;color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">s, see Note 23. Leases and subleases.</span></div>
CY2023Q4 ifrs-full Financial Liabilities
FinancialLiabilities
47975000 usd
CY2022Q4 ifrs-full Financial Liabilities
FinancialLiabilities
103103000 usd
CY2023Q4 ifrs-full Cash And Cash Equivalents
CashAndCashEquivalents
191081000 usd
CY2023Q4 ptv Short Term Investment
ShortTermInvestment
136062000 usd
CY2023Q4 ifrs-full Noncurrent Financial Assets At Fair Value Through Profit Or Loss
NoncurrentFinancialAssetsAtFairValueThroughProfitOrLoss
317841000 usd
CY2023 ifrs-full Disclosure Of Commitments And Contingent Liabilities Explanatory
DisclosureOfCommitmentsAndContingentLiabilitiesExplanatory
Commitments and Contingencies <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group is a party to certain licensing agreements where the Group is licensing IP from third parties. In consideration for such licenses, the Group has made upfront payments and may be required to make additional contingent payments based on developmental and sales milestones and/or royalty on future sales. As of December 31, 2023, certain milestone events have not yet occurred, and therefore, the Group does not have a present obligation to make the related payments in respect of the licenses. Such milestones are dependent on events that are outside of the control of the Group, and many of these milestone events are remote of occurring. As of December 31, 2023 and December 31, 2022, payments in respect of developmental milestones that are dependent on events that are outside the control of the Group but are reasonably possible to occur amounted to approximately $7,371 and $8,666, respectively. These milestone amounts represent an aggregate of multiple milestone payments depending on different milestone events in multiple agreements. The probability that all such milestone events will occur in the aggregate is remote. Payments made to license IP represent the acquisition cost of intangible assets. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group was a party to certain sponsored research arrangements and is a party to arrangements with contract manufacturing and contract research organizations, whereby the counterparty provides the Group with research and/or manufacturing services. As of December 31, 2023 and 2022, the noncancellable commitments in respect of such contracts amounted to approximately $16,422 and $11,288, respectively.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In March 2024, a complaint was filed in Massachusetts District Court against the Group alleging breach of contract with respect to certain payments alleged to be owed to a previous employee of a Group subsidiary based on purported terms of a contract between such individual and the Group. The Group intends to defend itself vigorously though the ultimate outcome of this matter and the timing for resolution remains uncertain. No determination has been made that a loss, if any, arising from this matter is probable or that the amount of any such loss, or range of loss, is reasonably estimable.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group is involved from time-to-time in various legal proceedings arising in the normal course of business. Although the outcomes of these legal proceedings are inherently difficult to predict, the Group does not expect the resolution of such legal proceedings to have a material adverse effect on its financial position or results of operations. The Group did not book any provisions and did not identify any contingent liabilities requiring disclosure for any legal proceedings other than already included above for the years ended December 31, 2023 and 2022.</span></div>
CY2023Q4 ifrs-full Estimated Financial Effect Of Contingent Liabilities
EstimatedFinancialEffectOfContingentLiabilities
7371000 usd
CY2022Q4 ifrs-full Estimated Financial Effect Of Contingent Liabilities
EstimatedFinancialEffectOfContingentLiabilities
8666000 usd
CY2023Q4 ifrs-full Contractual Capital Commitments
ContractualCapitalCommitments
16422000 usd
CY2022Q4 ifrs-full Contractual Capital Commitments
ContractualCapitalCommitments
11288000 usd
CY2023 ifrs-full Disclosure Of Transactions Between Related Parties Explanatory
DisclosureOfTransactionsBetweenRelatedPartiesExplanatory
Related Parties Transactions <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Related Party Subleases and Royalties </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During 2019, the Group executed a sublease agreement with a related party, Gelesis. As of December 31, 2022, the sublease receivable amounted to $1,285. During 2023, the sublease receivable was written down to $0 as Gelesis ceased operations and filed for bankruptcy.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group recorded $23, $89 and $113 of interest income with respect to the sublease during the years ended December 31, 2023, 2022, and 2021, respectively, which is presented within finance income in the Consolidated Statement of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group received royalties from Gelesis on its product sales. The Group recorded zero, $509, and $231 of royalty revenue during the years ended December 31, 2023, 2022, 2021, respectively, which is presented in contract revenue in the Consolidated Statement of Comprehensive Income/(Loss).</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Key Management Personnel Compensation</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Key management includes executive directors and members of the executive management team of the Group (not including non-executive directors). The key management personnel compensation of the Group was as follows for the years ended December 31: </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term employee benefits</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">9,714</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,162 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,612 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Post-employment benefits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">41</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">55 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">54 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Termination Benefits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">417</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">152 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">599</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,741 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,045 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,772</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,109 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,711 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term employee benefits include salaries, health care and other non-cash benefits. Post-employment benefits include 401K contributions from the Group. Termination benefits include severance pay. Share-based payments are generally subject to vesting terms over future periods. See Note 9. Share-based Payments. As of 12/31/2023, the payable due to the key management employees was $4,732.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In addition the Group paid remuneration to non-executive directors in the amounts of $475, $655 and $605 for the years ended December 31, 2023, 2022 and 2021, respectively. Also, the Group incurred $373, $365, and $161 of stock based compensation expense for such non-executive directors for the years ended December 31, 2023, 2022, and 2021, respectively.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the years ended December 31, 2023 and 2022, the Group incurred $46, and $51, respectively, of expenses paid to related parties.</span></div><div><span style="background-color:#ffffff;color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Convertible Notes Issued to Directors</span></div><div style="margin-bottom:5pt"><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain related parties of the Group have invested in convertible notes issued by the Group’s subsidiaries. As of </span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">December 31, 2023 and December 31, 2022,</span><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> the outstanding related party notes payable</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> totaled $104 and $99,</span><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> respectively, including principal and interest. </span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The notes issued to related parties bear interest rates, maturity dates, discounts and other contractual terms that are the same as those issued to outside investors during the same issuances.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Directors’ and Senior Managers’ Shareholdings and Share Incentive Awards</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Directors and senior managers hold beneficial interests in shares in the following businesses and sourcing companies as of December 31, 2023:</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:23.445%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:28.293%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.566%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:11.475%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.566%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:9.055%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Business name (share class)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of shares held as of December 31, 2023</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of options held as of December 31, 2023</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of RSUs held as of December 31, 2023</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Ownership<br/>interest¹</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Directors:</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Robert Langer</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">250,000</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">82,500</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.09</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Raju Kucherlapati</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Enlight (Class B Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">30,000</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr John LaMattina</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Akili (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">56,554</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.07</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,000</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15,000</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.24</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Senior Managers:</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="padding:0 1pt"></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Bharatt Chowrira</span></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna (Common)</span></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,000</span></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.01</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Ownership interests as of December 31, 2023 are calculated on a diluted basis, including issued and outstanding shares, warrants and options (and written commitments to issue options) but excluding unallocated shares authorized to be issued pursuant to equity incentive plans and any shares issuable upon conversion of outstanding convertible promissory notes.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Dr John LaMattina holds convertible notes issued by Appeering in the aggregate principal amount of $50,000.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span><br/></span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Directors and senior managers hold 23,547,554 ordinary shares and 11.5 percent voting rights of the Group as of December 31, 2023. This amount excludes options to purchase 2,262,500 ordinary shares. This amount also excludes 7,301,547 shares, which are issuable based on the terms of performance based RSU awards granted to certain senior managers covering the financial years 2023, 2022 and 2021, and 102,732 shares, which are issuable to directors immediately prior to the Group's 2024 Annual General Meeting of Stockholders, based on the terms of the RSU awards granted to non-executive directors in 2023. Such shares will be issued to such senior managers and non-executive directors in future periods provided that performance and/or service conditions are met, and certain of the shares will be withheld for payment of customary withholding taxes.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">See Note 7. Investment in Notes from Associates for details on the notes issued by Gelesis and Vedanta to the Group. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2023, the Group has a receivable from Sonde and Vedanta in the amount of $1,569.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">See Note 6. Investments in Associates for details on the execution and termination of Merger Agreement with Gelesis.</span></div>
CY2023 ifrs-full Disclosure Of Amounts Incurred By Entity For Provision Of Key Management Personnel Services Provided By Separate Management Entities Explanatory
DisclosureOfAmountsIncurredByEntityForProvisionOfKeyManagementPersonnelServicesProvidedBySeparateManagementEntitiesExplanatory
The key management personnel compensation of the Group was as follows for the years ended December 31: <div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term employee benefits</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">9,714</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,162 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,612 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Post-employment benefits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">41</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">55 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">54 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Termination Benefits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">417</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">152 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">599</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,741 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,045 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,772</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,109 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,711 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div>
CY2023 ifrs-full Key Management Personnel Compensation Shortterm Employee Benefits
KeyManagementPersonnelCompensationShorttermEmployeeBenefits
9714000 usd
CY2022 ifrs-full Key Management Personnel Compensation Shortterm Employee Benefits
KeyManagementPersonnelCompensationShorttermEmployeeBenefits
4162000 usd
CY2021 ifrs-full Key Management Personnel Compensation Shortterm Employee Benefits
KeyManagementPersonnelCompensationShorttermEmployeeBenefits
4612000 usd
CY2023 ifrs-full Key Management Personnel Compensation Postemployment Benefits
KeyManagementPersonnelCompensationPostemploymentBenefits
41000 usd
CY2022 ifrs-full Key Management Personnel Compensation Postemployment Benefits
KeyManagementPersonnelCompensationPostemploymentBenefits
55000 usd
CY2021 ifrs-full Key Management Personnel Compensation Postemployment Benefits
KeyManagementPersonnelCompensationPostemploymentBenefits
54000 usd
CY2023 ifrs-full Key Management Personnel Compensation Termination Benefits
KeyManagementPersonnelCompensationTerminationBenefits
417000 usd
CY2022 ifrs-full Key Management Personnel Compensation Termination Benefits
KeyManagementPersonnelCompensationTerminationBenefits
152000 usd
CY2021 ifrs-full Key Management Personnel Compensation Termination Benefits
KeyManagementPersonnelCompensationTerminationBenefits
0 usd
CY2023 ifrs-full Key Management Personnel Compensation Sharebased Payment
KeyManagementPersonnelCompensationSharebasedPayment
599000 usd
CY2022 ifrs-full Key Management Personnel Compensation Sharebased Payment
KeyManagementPersonnelCompensationSharebasedPayment
2741000 usd
CY2021 ifrs-full Key Management Personnel Compensation Sharebased Payment
KeyManagementPersonnelCompensationSharebasedPayment
4045000 usd
CY2023 ifrs-full Key Management Personnel Compensation
KeyManagementPersonnelCompensation
10772000 usd
CY2022 ifrs-full Key Management Personnel Compensation
KeyManagementPersonnelCompensation
7109000 usd
CY2021 ifrs-full Key Management Personnel Compensation
KeyManagementPersonnelCompensation
8711000 usd
CY2023 ifrs-full Disclosure Of Income Tax Explanatory
DisclosureOfIncomeTaxExplanatory
Taxation <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax on the profit or loss for the year comprises current and deferred income tax. Tax is recognized in the Consolidated Statement of Comprehensive Income/(Loss) except to the extent that it relates to items recognized directly in equity.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For the years ended December 31, 2023, 2022 and 2021, the Group filed a consolidated U.S. federal income tax return which included all subsidiaries in which the Group owned greater than 80 percent of the vote and value. For the years ended December 31, 2023, 2022 and 2021, the Group filed certain consolidated state income tax returns which included all subsidiaries in which the Group owned greater than 50 percent of the vote and value. The remaining subsidiaries file separate U.S. tax returns.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amounts recognized in Consolidated Statement of Comprehensive Income/(Loss):</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(66,628)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(37,065)</span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(62,709)</span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income tax expense/(benefit)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">30,525</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(55,719)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,756 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) before taxes</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(36,103)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(92,783)</span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(58,953)</span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Recognized Income Tax Expense/(Benefit):</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Federal - current</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,246)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,065 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,138 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">State - current</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(46)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,336 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">109 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total current income tax expense/(benefit)</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,292)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,401 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,247 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Federal - deferred</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">29,294</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(48,240)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,416)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">State - deferred</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,523</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(21,880)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,075)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:64.354%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total deferred income tax expense/(benefit)</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">32,817</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(70,120)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(18,491)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total income tax expense/(benefit), recognized</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">30,525</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(55,719)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,756 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The income tax expense/(benefit) was $30,525, $(55,719) and $3,756 in 2023, 2022 and 2021 respectively. The increase in tax expense for the year ended December 31, 2023 was primarily attributable to a lower pre-tax loss in the tax consolidated U.S. group, the tax in respect of the sale of future royalties to Royalty Pharma and the tax impact of derecognizing previously recognized deferred tax assets that are no longer expected to be utilized.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reconciliation of Effective Tax Rate</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group is primarily subject to taxation in the U.S. A reconciliation of the U.S. federal statutory tax rate to the effective tax rate is as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:28.596%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.417%"></td><td style="width:0.1%"></td></tr><tr><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></td><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">%</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">US federal statutory rate</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(7,573)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(19,486)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21.00 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(12,380)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21.00 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">State taxes, net of federal effect</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,974)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11.01</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,043)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.67 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,484)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7.61 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax credits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(9,167)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25.39</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,876)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7.41 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,056)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.58 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Stock-based compensation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">589</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1.63)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">788 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.85)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">555 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.94)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income/(costs) – fair value accounting</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(556)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.54</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(28,783)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">31.02 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,017)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.42 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Loss with respect to associate for which no deferred tax asset is recognized</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">249</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(0.69)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,413 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1.52)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,542 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(19.58)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revaluation of deferred due to rate change</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,856)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9.54 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Nondeductible compensation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">872</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2.42)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">300 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.32)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">746 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1.27)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Recognition of deferred tax assets and tax benefits not previously recognized</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(433)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.20</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(184)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.20 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(414)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.70 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Unrecognized deferred tax asset</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">83,984</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(232.63)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,287 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(18.63)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,375 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(24.38)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(17,506)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">48.49</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,572)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.85 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,321</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3.65)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">293 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.32)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">889 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1.51)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Worthless stock deduction</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(17,281)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47.87</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">30,525</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(84.52)</span></td><td style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:0 1pt"></td><td colspan="2" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(55,719)</span></td><td style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">60.05 </span></td><td style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:0 1pt"></td><td colspan="3" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,756</span></td><td colspan="2" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6.37)</span></td><td style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group is also subject to taxation in the UK, but to date, no taxable income has been generated in the UK. Changes in corporate tax rates can change both the current tax expense (benefit) as well as the deferred tax expense (benefit). </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred Tax Assets and Liabilities </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets have been recognized in the U.S. jurisdiction in respect of the following items:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="display:none"></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating tax losses</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,849</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48,317 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax credits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,425</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,101 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,210</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,423 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Capitalized research &amp; development expenditures</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">39,422</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">36,084 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment in Associates</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,036 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Lease liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,133</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,143 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sale of future royalties </span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,920</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other temporary differences</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,770</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,957 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">93,729</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">127,061 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(53,411)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(47,877)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Right of use assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,330)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,519)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Property and equipment, net</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,637)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,348)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment in Associates</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(755)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax liabilities</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(58,133)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(53,744)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets (liabilities), net</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,596</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">73,317 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax liabilities, net, recognized</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(52,462)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(19,645)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets (liabilities), net, not recognized</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">88,058</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">92,962 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has recognized deferred tax assets due to future reversals of existing taxable temporary differences that will be sufficient to recover the deferred tax assets. Our unrecognized deferred tax assets of $88,058 are primarily related to tax credits, capitalized research &amp; development expenditures and deferred tax asset related to the sale of future royalties to Royalty Pharma. The Group does not believe it is probable that future taxable profit will be available to support the realizability of these unrecognized deferred tax assets. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Unrecognized Deferred Tax Assets</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets have not been recognized in respect of the following carryforward losses, credits and temporary differences, because it is not probable that future taxable profit will be available against which the Group can use the benefits therefrom.</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:52.233%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="6" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:0 1pt"></td><td colspan="6" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></td><td colspan="3" style="padding:0 1pt"></td></tr><tr style="height:9pt"><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Gross Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Tax Effected</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Gross Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Tax Effected</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deductible temporary difference</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">353,323</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">83,741</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">132,145 </span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">33,544 </span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax losses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,681</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,849</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">219,466 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48,317 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax credits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">468</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">468</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,101 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,101 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">367,472</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">88,058</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">362,712 </span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">92,962 </span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax Losses and Tax Credits Carryforwards </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax losses and tax credits for which no deferred tax asset was recognized are presented below:</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:52.233%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" rowspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="6" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:0 1pt"></td><td colspan="6" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"></td></tr><tr style="height:9pt"><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Gross Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Tax Effected</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Gross Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Tax Effected</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax losses expiring:</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Within 10 years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,741</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,284</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">23,930 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,387 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">More than 10 years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,635</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,455</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">42,822 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,509 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Available Indefinitely</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,305</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,110</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">152,714 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">32,421 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,681</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,849</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">219,466 </span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48,317 </span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax credits expiring:</span></td><td colspan="3" style="border-top:0.5pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.5pt solid #183964;padding:0 1pt"></td><td colspan="3" style="border-top:0.5pt solid #183964;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;border-top:0.5pt solid #183964;padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;border-top:0.5pt solid #183964;padding:0 1pt"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Within 10 years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">43</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">43</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">43 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">43 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">More than 10 years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">425</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">425</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,058 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,058 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Available indefinitely</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">468</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">468</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,101 </span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,101 </span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group had U.S. federal net operating losses carry forwards (“NOLs”) of $13,681, $219,466 and $215,400 as of December 31, 2023, 2022 and 2021, respectively, which are available to offset future taxable income. These NOLs expire through 2037 with the exception of $2,305 which is not subject to expiration. The Group had U.S. federal research and development tax credits of approximately $1,396, $4,500 and $3,900 as of December 31, 2023, 2022 and 2021, respectively, which are available to offset future taxes that expire at various dates through 2043. The Group also had Federal Orphan Drug credits of approximately $930 and $6,100 as of December 31, 2023, and 2022, which are available to offset future taxes that expire at various dates through 2043. A portion of these federal NOLs and credits can only be used to offset the profits from the Group’s subsidiaries who file separate federal tax returns. These NOLs and credits are subject to review and possible adjustment by the Internal Revenue Service.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group had state net operating losses carry forwards (“NOLs”) of approximately $111,446, $71,700 and $27,900 for the years ended December 31, 2023, 2022 and 2021, respectively, which are available to offset future taxable income. These NOLs expire at various dates beginning in 2030. The Group had Massachusetts research and development tax credits of approximately $98, $600 and $1,300 for the years ended December 31, 2023, 2022 and 2021, respectively, which are available to offset future taxes and expire at various dates through 2038. These NOLs and credits are subject to review and possible adjustment by state taxing authority.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Utilization of the NOLs and research and development credit carryforwards may be subject to a substantial annual limitation under Section 382 of the Internal Revenue Code of 1986 due to ownership change limitations that have occurred previously or that could occur in the future. These ownership changes may limit the amount of NOL and research and development credit carryforwards that can be utilized annually to offset future taxable income and tax, respectively. The Group has performed a Section 382 analysis through December 31, 2023. The results of this analysis concluded that certain net operating losses were subject to limitation under Section 382 of the Internal Revenue Code. None of the Group’s net operating losses which are subject to a Section 382 limitation has been recognized in the financial statements. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax Balances</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The tax related balances presented in the Statement of Financial Position are as follows:</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:11pt"><td colspan="9" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income tax receivable – current </span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,746</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,040 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other payables</span></div></td><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(57)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Uncertain Tax Positions</span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has no uncertain tax positions as of December 31, 2023. U.S. corporations are routinely subject to audit by federal and state tax authorities in the normal course of business.</span></div>
CY2023 ptv Percentage Vote And Value Of Subsidiaries Included In The Group Consolidated Federal Tax Return
PercentageVoteAndValueOfSubsidiariesIncludedInTheGroupConsolidatedFederalTaxReturn
0.80
CY2022 ptv Percentage Vote And Value Of Subsidiaries Included In The Group Consolidated Federal Tax Return
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CY2021 ptv Percentage Vote And Value Of Subsidiaries Included In The Group Consolidated Federal Tax Return
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0.80
CY2023 ptv Percentage Vote And Value Of Subsidiaries In The Group Consolidated State Tax Return
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CY2022 ptv Percentage Vote And Value Of Subsidiaries In The Group Consolidated State Tax Return
PercentageVoteAndValueOfSubsidiariesInTheGroupConsolidatedStateTaxReturn
0.50
CY2021 ptv Percentage Vote And Value Of Subsidiaries In The Group Consolidated State Tax Return
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CY2021 ptv Rate Of Tax Credits Reconciliation Of Effective Tax Rate
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-0.0858
CY2023 ptv Share Based Payment Expenses Non Deductible Reconciliation Of Effective Tax Rate
ShareBasedPaymentExpensesNonDeductibleReconciliationOfEffectiveTaxRate
589000 usd
CY2023 ptv Rate Of Share Based Payment Expenses Non Deductible Reconciliation Of Effective Tax Rate
RateOfShareBasedPaymentExpensesNonDeductibleReconciliationOfEffectiveTaxRate
-0.0163
CY2022 ptv Tax Credit Reconciliation Of Effective Tax Rate
TaxCreditReconciliationOfEffectiveTaxRate
6876000 usd
CY2022 ptv Rate Of Tax Credits Reconciliation Of Effective Tax Rate
RateOfTaxCreditsReconciliationOfEffectiveTaxRate
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CY2021 ptv Tax Credit Reconciliation Of Effective Tax Rate
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CY2023 ifrs-full Profit Loss
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CY2022 ifrs-full Profit Loss
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CY2021 ifrs-full Profit Loss
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CY2023 ifrs-full Income Tax Expense Continuing Operations
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CY2022 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
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CY2021 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
3756000 usd
CY2023 ifrs-full Profit Loss Before Tax
ProfitLossBeforeTax
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CY2022 ifrs-full Profit Loss Before Tax
ProfitLossBeforeTax
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CY2021 ifrs-full Profit Loss Before Tax
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CY2023 ifrs-full Current Tax Expense Income
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-2292000 usd
CY2022 ifrs-full Current Tax Expense Income
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14401000 usd
CY2021 ifrs-full Current Tax Expense Income
CurrentTaxExpenseIncome
22247000 usd
CY2023 ifrs-full Deferred Tax Expense Income
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CY2022 ifrs-full Deferred Tax Expense Income
DeferredTaxExpenseIncome
-70120000 usd
CY2021 ifrs-full Deferred Tax Expense Income
DeferredTaxExpenseIncome
-18491000 usd
CY2023 ifrs-full Deferred Tax Expense Income Recognised In Profit Or Loss
DeferredTaxExpenseIncomeRecognisedInProfitOrLoss
30525000 usd
CY2022 ifrs-full Deferred Tax Expense Income Recognised In Profit Or Loss
DeferredTaxExpenseIncomeRecognisedInProfitOrLoss
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CY2021 ifrs-full Deferred Tax Expense Income Recognised In Profit Or Loss
DeferredTaxExpenseIncomeRecognisedInProfitOrLoss
3756000 usd
CY2023 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
30525000 usd
CY2022 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
-55719000 usd
CY2021 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
3756000 usd
CY2023 ifrs-full Tax Expense Income At Applicable Tax Rate
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-7573000 usd
CY2023 ifrs-full Applicable Tax Rate
ApplicableTaxRate
0.2100
CY2022 ifrs-full Tax Expense Income At Applicable Tax Rate
TaxExpenseIncomeAtApplicableTaxRate
-19486000 usd
CY2022 ifrs-full Applicable Tax Rate
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0.2100
CY2021 ifrs-full Tax Expense Income At Applicable Tax Rate
TaxExpenseIncomeAtApplicableTaxRate
-12380000 usd
CY2021 ifrs-full Applicable Tax Rate
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0.2100
CY2023 ptv Effects Of State Tax Rate In Us Reconciliation Of Effective Tax Rate
EffectsOfStateTaxRateInUSReconciliationOfEffectiveTaxRate
-3974000 usd
CY2023 ptv Rate Of Effects Of State Tax Rate In Us
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CY2022 ptv Effects Of State Tax Rate In Us Reconciliation Of Effective Tax Rate
EffectsOfStateTaxRateInUSReconciliationOfEffectiveTaxRate
-8043000 usd
CY2022 ptv Rate Of Effects Of State Tax Rate In Us
RateOfEffectsOfStateTaxRateInUS
0.0867
CY2021 ptv Effects Of State Tax Rate In Us Reconciliation Of Effective Tax Rate
EffectsOfStateTaxRateInUSReconciliationOfEffectiveTaxRate
-4484000 usd
CY2021 ptv Rate Of Effects Of State Tax Rate In Us
RateOfEffectsOfStateTaxRateInUS
0.0761
CY2023 ptv Tax Credit Reconciliation Of Effective Tax Rate
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CY2023 ptv Rate Of Tax Credits Reconciliation Of Effective Tax Rate
RateOfTaxCreditsReconciliationOfEffectiveTaxRate
-0.2539
CY2022 ptv Share Based Payment Expenses Non Deductible Reconciliation Of Effective Tax Rate
ShareBasedPaymentExpensesNonDeductibleReconciliationOfEffectiveTaxRate
788000 usd
CY2022 ptv Rate Of Share Based Payment Expenses Non Deductible Reconciliation Of Effective Tax Rate
RateOfShareBasedPaymentExpensesNonDeductibleReconciliationOfEffectiveTaxRate
-0.0085
CY2021 ptv Share Based Payment Expenses Non Deductible Reconciliation Of Effective Tax Rate
ShareBasedPaymentExpensesNonDeductibleReconciliationOfEffectiveTaxRate
555000 usd
CY2021 ptv Rate Of Share Based Payment Expenses Non Deductible Reconciliation Of Effective Tax Rate
RateOfShareBasedPaymentExpensesNonDeductibleReconciliationOfEffectiveTaxRate
-0.0094
CY2023 ptv Finance Income Costs Fair Value Accounting Reconciliation Of Effective Tax Rate
FinanceIncomeCostsFairValueAccountingReconciliationOfEffectiveTaxRate
-556000 usd
CY2023 ptv Rate Of Finance Income Costs Fair Value Accounting Reconciliation Of Effective Tax Rate
RateOfFinanceIncomeCostsFairValueAccountingReconciliationOfEffectiveTaxRate
0.0154
CY2022 ptv Finance Income Costs Fair Value Accounting Reconciliation Of Effective Tax Rate
FinanceIncomeCostsFairValueAccountingReconciliationOfEffectiveTaxRate
-28783000 usd
CY2022 ptv Rate Of Finance Income Costs Fair Value Accounting Reconciliation Of Effective Tax Rate
RateOfFinanceIncomeCostsFairValueAccountingReconciliationOfEffectiveTaxRate
0.3102
CY2021 ptv Finance Income Costs Fair Value Accounting Reconciliation Of Effective Tax Rate
FinanceIncomeCostsFairValueAccountingReconciliationOfEffectiveTaxRate
-2017000 usd
CY2021 ptv Rate Of Finance Income Costs Fair Value Accounting Reconciliation Of Effective Tax Rate
RateOfFinanceIncomeCostsFairValueAccountingReconciliationOfEffectiveTaxRate
0.0342
CY2023 ptv Loss With Respect To Associate For Which No Deferred Tax Asset Is Recognized Reconciliation Of Effective Tax Rate
LossWithRespectToAssociateForWhichNoDeferredTaxAssetIsRecognizedReconciliationOfEffectiveTaxRate
249000 usd
CY2023 ptv Rate Of Loss With Respect To Associate For Which No Deferred Tax Asset Is Recognized Reconciliation Of Effective Tax Rate
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-0.0069
CY2022 ptv Loss With Respect To Associate For Which No Deferred Tax Asset Is Recognized Reconciliation Of Effective Tax Rate
LossWithRespectToAssociateForWhichNoDeferredTaxAssetIsRecognizedReconciliationOfEffectiveTaxRate
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CY2022 ptv Rate Of Loss With Respect To Associate For Which No Deferred Tax Asset Is Recognized Reconciliation Of Effective Tax Rate
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-0.0152
CY2021 ptv Loss With Respect To Associate For Which No Deferred Tax Asset Is Recognized Reconciliation Of Effective Tax Rate
LossWithRespectToAssociateForWhichNoDeferredTaxAssetIsRecognizedReconciliationOfEffectiveTaxRate
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CY2021 ptv Rate Of Loss With Respect To Associate For Which No Deferred Tax Asset Is Recognized Reconciliation Of Effective Tax Rate
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-0.1958
CY2023 ptv Adjustments Related To Change In Blend State Rate
AdjustmentsRelatedToChangeInBlendStateRate
0 usd
CY2023 ptv Tax Rate Effect Of Adjustments Related To Change In Blend State Rate
TaxRateEffectOfAdjustmentsRelatedToChangeInBlendStateRate
0.0000
CY2022 ptv Adjustments Related To Change In Blend State Rate
AdjustmentsRelatedToChangeInBlendStateRate
-8856000 usd
CY2022 ptv Tax Rate Effect Of Adjustments Related To Change In Blend State Rate
TaxRateEffectOfAdjustmentsRelatedToChangeInBlendStateRate
0.0954
CY2021 ptv Adjustments Related To Change In Blend State Rate
AdjustmentsRelatedToChangeInBlendStateRate
0 usd
CY2021 ptv Tax Rate Effect Of Adjustments Related To Change In Blend State Rate
TaxRateEffectOfAdjustmentsRelatedToChangeInBlendStateRate
0
CY2023 ptv Executive Compensation Reconciliation Of Effective Tax Rate
ExecutiveCompensationReconciliationOfEffectiveTaxRate
872000 usd
CY2023 ptv Rate Of Executive Compensation Reconciliation Of Effective Tax Rate
RateOfExecutiveCompensationReconciliationOfEffectiveTaxRate
-0.0242
CY2022 ptv Executive Compensation Reconciliation Of Effective Tax Rate
ExecutiveCompensationReconciliationOfEffectiveTaxRate
300000 usd
CY2022 ptv Rate Of Executive Compensation Reconciliation Of Effective Tax Rate
RateOfExecutiveCompensationReconciliationOfEffectiveTaxRate
-0.0032
CY2021 ptv Executive Compensation Reconciliation Of Effective Tax Rate
ExecutiveCompensationReconciliationOfEffectiveTaxRate
746000 usd
CY2021 ptv Rate Of Executive Compensation Reconciliation Of Effective Tax Rate
RateOfExecutiveCompensationReconciliationOfEffectiveTaxRate
-0.0127
CY2023 ptv Deferred Tax Assets And Benefits Not Previously Recognised Reconciliation Of Effective Tax Rate
DeferredTaxAssetsAndBenefitsNotPreviouslyRecognisedReconciliationOfEffectiveTaxRate
433000 usd
CY2023 ptv Tax Rate Effect Of Deferred Tax Assets And Benefits Not Previously Recognised
TaxRateEffectOfDeferredTaxAssetsAndBenefitsNotPreviouslyRecognised
-0.0120
CY2022 ptv Deferred Tax Assets And Benefits Not Previously Recognised Reconciliation Of Effective Tax Rate
DeferredTaxAssetsAndBenefitsNotPreviouslyRecognisedReconciliationOfEffectiveTaxRate
184000 usd
CY2022 ptv Tax Rate Effect Of Deferred Tax Assets And Benefits Not Previously Recognised
TaxRateEffectOfDeferredTaxAssetsAndBenefitsNotPreviouslyRecognised
-0.0020
CY2021 ptv Deferred Tax Assets And Benefits Not Previously Recognised Reconciliation Of Effective Tax Rate
DeferredTaxAssetsAndBenefitsNotPreviouslyRecognisedReconciliationOfEffectiveTaxRate
414000 usd
CY2021 ptv Tax Rate Effect Of Deferred Tax Assets And Benefits Not Previously Recognised
TaxRateEffectOfDeferredTaxAssetsAndBenefitsNotPreviouslyRecognised
-0.0070
CY2023 ifrs-full Tax Effect Of Tax Losses
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83984000 usd
CY2023 ifrs-full Tax Rate Effect Of Tax Losses
TaxRateEffectOfTaxLosses
-2.3263
CY2022 ifrs-full Tax Effect Of Tax Losses
TaxEffectOfTaxLosses
17287000 usd
CY2022 ifrs-full Tax Rate Effect Of Tax Losses
TaxRateEffectOfTaxLosses
-0.1863
CY2021 ifrs-full Tax Effect Of Tax Losses
TaxEffectOfTaxLosses
14375000 usd
CY2021 ifrs-full Tax Rate Effect Of Tax Losses
TaxRateEffectOfTaxLosses
-0.2438
CY2023 ptv Deconsolidation Adjustments Reconciliation Of Effective Tax Rate
DeconsolidationAdjustmentsReconciliationOfEffectiveTaxRate
17506000 usd
CY2023 ptv Rate Of Deconsolidation Adjustments Reconciliation Of Effective Tax Rate
RateOfDeconsolidationAdjustmentsReconciliationOfEffectiveTaxRate
-0.4849
CY2022 ptv Deconsolidation Adjustments Reconciliation Of Effective Tax Rate
DeconsolidationAdjustmentsReconciliationOfEffectiveTaxRate
3572000 usd
CY2022 ptv Rate Of Deconsolidation Adjustments Reconciliation Of Effective Tax Rate
RateOfDeconsolidationAdjustmentsReconciliationOfEffectiveTaxRate
-0.0385
CY2021 ptv Deconsolidation Adjustments Reconciliation Of Effective Tax Rate
DeconsolidationAdjustmentsReconciliationOfEffectiveTaxRate
0 usd
CY2021 ptv Rate Of Deconsolidation Adjustments Reconciliation Of Effective Tax Rate
RateOfDeconsolidationAdjustmentsReconciliationOfEffectiveTaxRate
0
CY2023 ifrs-full Other Tax Effects For Reconciliation Between Accounting Profit And Tax Expense Income
OtherTaxEffectsForReconciliationBetweenAccountingProfitAndTaxExpenseIncome
1321000 usd
CY2023 ifrs-full Other Tax Rate Effects For Reconciliation Between Accounting Profit And Tax Expense Income
OtherTaxRateEffectsForReconciliationBetweenAccountingProfitAndTaxExpenseIncome
-0.0365
CY2022 ifrs-full Other Tax Effects For Reconciliation Between Accounting Profit And Tax Expense Income
OtherTaxEffectsForReconciliationBetweenAccountingProfitAndTaxExpenseIncome
293000 usd
CY2022 ifrs-full Other Tax Rate Effects For Reconciliation Between Accounting Profit And Tax Expense Income
OtherTaxRateEffectsForReconciliationBetweenAccountingProfitAndTaxExpenseIncome
-0.0032
CY2021 ifrs-full Other Tax Effects For Reconciliation Between Accounting Profit And Tax Expense Income
OtherTaxEffectsForReconciliationBetweenAccountingProfitAndTaxExpenseIncome
889000 usd
CY2021 ifrs-full Other Tax Rate Effects For Reconciliation Between Accounting Profit And Tax Expense Income
OtherTaxRateEffectsForReconciliationBetweenAccountingProfitAndTaxExpenseIncome
-0.0151
CY2023 ptv Stock Deduction Reconciliation Of Effective Tax Rate
StockDeductionReconciliationOfEffectiveTaxRate
-17281000 usd
CY2023 ptv Tax Rate Effect Of Stock Deduction Reconciliation Of Effective Tax Rate
TaxRateEffectOfStockDeductionReconciliationOfEffectiveTaxRate
0.4787
CY2022 ptv Stock Deduction Reconciliation Of Effective Tax Rate
StockDeductionReconciliationOfEffectiveTaxRate
0 usd
CY2022 ptv Tax Rate Effect Of Stock Deduction Reconciliation Of Effective Tax Rate
TaxRateEffectOfStockDeductionReconciliationOfEffectiveTaxRate
0
CY2021 ptv Stock Deduction Reconciliation Of Effective Tax Rate
StockDeductionReconciliationOfEffectiveTaxRate
0 usd
CY2021 ptv Tax Rate Effect Of Stock Deduction Reconciliation Of Effective Tax Rate
TaxRateEffectOfStockDeductionReconciliationOfEffectiveTaxRate
0
CY2023 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
30525000 usd
CY2023 ifrs-full Average Effective Tax Rate
AverageEffectiveTaxRate
-0.8452
CY2022 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
-55719000 usd
CY2022 ifrs-full Average Effective Tax Rate
AverageEffectiveTaxRate
0.6005
CY2021 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
3756000 usd
CY2021 ifrs-full Average Effective Tax Rate
AverageEffectiveTaxRate
-0.0637
CY2023 ifrs-full Disclosure Of Deferred Taxes Explanatory
DisclosureOfDeferredTaxesExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets have been recognized in the U.S. jurisdiction in respect of the following items:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:75.869%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td><td colspan="3" style="display:none"></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="display:none"></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating tax losses</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,849</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48,317 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax credits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,425</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,101 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,210</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,423 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Capitalized research &amp; development expenditures</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">39,422</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">36,084 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment in Associates</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,036 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Lease liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,133</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,143 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sale of future royalties </span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,920</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other temporary differences</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,770</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,957 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">93,729</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">127,061 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(53,411)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(47,877)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Right of use assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,330)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,519)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Property and equipment, net</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,637)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,348)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment in Associates</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(755)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax liabilities</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(58,133)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(53,744)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets (liabilities), net</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,596</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">73,317 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax liabilities, net, recognized</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(52,462)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(19,645)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td><td colspan="3" style="display:none"></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets (liabilities), net, not recognized</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">88,058</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">92,962 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="display:none"></td></tr></table></div>
CY2023 ifrs-full Disclosure Of Temporary Difference Unused Tax Losses And Unused Tax Credits Explanatory
DisclosureOfTemporaryDifferenceUnusedTaxLossesAndUnusedTaxCreditsExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets have not been recognized in respect of the following carryforward losses, credits and temporary differences, because it is not probable that future taxable profit will be available against which the Group can use the benefits therefrom.</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.899%"><tr><td style="width:1.0%"></td><td style="width:52.233%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:0.1%"></td><td style="width:0.406%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.415%"></td><td style="width:0.1%"></td><td style="width:1.0%"></td><td style="width:10.416%"></td><td style="width:0.1%"></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"></td><td colspan="6" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2023</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:0 1pt"></td><td colspan="6" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2022</span></div><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></td><td colspan="3" style="padding:0 1pt"></td></tr><tr style="height:9pt"><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Gross Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Tax Effected</span></td><td colspan="3" style="padding:0 1pt"></td><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Gross Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Tax Effected</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deductible temporary difference</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">353,323</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">83,741</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">132,145 </span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">33,544 </span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax losses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,681</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,849</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">219,466 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48,317 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax credits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">468</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">468</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,101 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,101 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">367,472</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">88,058</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"></td><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">362,712 </span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">92,962 </span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"></td></tr></table></div>
CY2023Q4 ptv Trade Receivables Income Tax Receivable
TradeReceivablesIncomeTaxReceivable
11746000 usd
CY2022Q4 ptv Trade Receivables Income Tax Receivable
TradeReceivablesIncomeTaxReceivable
10040000 usd
CY2023Q4 ptv Income Tax Payable
IncomeTaxPayable
0 usd
CY2022Q4 ptv Income Tax Payable
IncomeTaxPayable
57000 usd
CY2023 ifrs-full Disclosure Of Events After Reporting Period Explanatory
DisclosureOfEventsAfterReportingPeriodExplanatory
Subsequent Events <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has evaluated subsequent events after December 31, 2023, up to the date of issuance, April 25, 2024, of the Consolidated Financial Statements, and has not identified any recordable or disclosable events not otherwise reported in these Consolidated Financial Statements or notes thereto, except for the following:</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In January 2024, the Group launched two new Founded Entities (Seaport Therapeutics and Gallop Oncology) to advance certain programs from the Wholly-Owned Programs segment. Seaport Therapeutics ("Seaport") will advance certain central nervous system programs and relevant Glyph intellectual property. Gallop Oncology will advance LYT-200 and other galectin-9 intellectual property. The financial results of these programs were included in the Wholly-Owned Programs segment in the footnotes to the Consolidated Financial Statements, as of December 31, 2023 and 2022, and for the three years ended December 31, 2023, 2022 and 2021, respectively. Upon raising dilutive third-party financing, the financial results of these two entities will be included in the Controlled Founded Entities segment to the extent that the Group maintains control over these entities.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On May 9, 2022, the Group announced the commencement of a $50,000 share repurchase program ( the "Program") of its ordinary shares of one pence each. In February 2024, the Group completed the Program and has repurchased an aggregate of 20,182,863 ordinary shares under the Program. These shares have been held as treasury shares and are being used to settle the vesting of restricted stock units or exercise of options.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In March 2024, Karuna was acquired by Bristol Myers Squibb (“BMS”) in accordance with a definitive merger agreement signed in December 2023. As a result of this transaction, the Group received total proceeds of <span id="i5771117341fa4c339e6c04f3bed8c381_12477"></span>$292,672 before income tax in exchange for its holding of 886,885 shares of Karuna common stock. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In March 2024, the Group announced a proposed capital return of $100,000 to its shareholders by way of a tender offer (the "Tender Offer"). The Tender Offer is expected to be launched in early May, subject to market conditions and shareholder approval. If the full $100,000 is not returned, then the Group intends to return any remainder following the completion of the Tender Offer, by way of a special dividend.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In April 2024, Seaport Therapeutics, the Group's latest Founded Entity, raised $100,000 in a Series A financing, out of which $32,000 was invested by the Group. Following the Series A financing, the Group holds equity ownership in Seaport of 61.5 percent on a diluted basis. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In April 2024, the Gelesis' Chapter 7 Trustee provided notice that a third party bid to purchase the assets subject to the bankruptcy had been accepted as a stalking horse bid, subject to Bankruptcy Court approval. If such sale of the assets is ultimately approved by the Bankruptcy Court and consummated, it is expected that PureTech could recover a portion of its investment in Gelesis senior secured convertible promissory notes. The ultimate resolution of this matter, any potential recovery, and the associated timing remain uncertain. The Group has not recorded any amount in its Consolidated Financial Statements related to amounts that may be received as a result of the bankruptcy process.</span></div>

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