$PRTC
PureTech Health plc

2022 Q4 Form 20-F Financial Statement

#000178299923000004 Filed on April 28, 2023

View on sec.gov

Income Statement

Concept 2022 Q4 2022 2021
Revenue $8.588M $15.62M $17.39M
YoY Change -25.66% -10.19% 47.75%
Cost Of Revenue
YoY Change
Gross Profit
YoY Change
Gross Profit Margin
Selling, General & Admin $37.35M $60.99M $57.20M
YoY Change 18.14% 6.63% 15.7%
% of Gross Profit
Research & Development $67.85M $152.4M $110.5M
YoY Change 9.19% 37.99% 34.95%
% of Gross Profit
Depreciation & Amortization $4.599M $8.893M $7.290M
YoY Change 26.38% 21.99% 9.62%
% of Gross Profit
Operating Expenses $105.2M $152.4M $167.7M
YoY Change 12.21% -9.09% 27.7%
Operating Profit
YoY Change
Interest Expense -$7.841M -$80.51M $81.55M
YoY Change -108.13% -198.73% -42.45%
% of Operating Profit
Other Income/Expense, Net $76.16M $138.5M $9.780M
YoY Change 249.79% 1315.7% -408.52%
Pretax Income -$36.83M -$92.78M -$58.95M
YoY Change -202.36% 57.39% -410.75%
Income Tax -$23.23M -$55.72M $3.760M
% Of Pretax Income
Net Earnings -$22.01M -$37.07M -$60.56M
YoY Change -248.35% -38.8% -1111.02%
Net Earnings / Revenue -256.29% -237.32% -348.25%
Basic Earnings Per Share
Diluted Earnings Per Share -$0.08 -$0.18 -$211.3K
COMMON SHARES
Basic Shares Outstanding 278.6M shares
Diluted Shares Outstanding

Balance Sheet

Concept 2022 Q4 2022 2021
SHORT-TERM ASSETS
Cash & Short-Term Investments $352.2M $352.2M $467.8M
YoY Change -24.71% -24.71% 15.22%
Cash & Equivalents $149.9M $149.9M $465.7M
Short-Term Investments $202.4M $202.4M $2.100M
Other Short-Term Assets $11.62M $11.62M $10.80M
YoY Change 8.02% 7.56% 100.0%
Inventory
Prepaid Expenses
Receivables $11.87M $11.87M $3.200M
Other Receivables $10.49M $10.49M $20.00M
Total Short-Term Assets $386.2M $386.2M $501.8M
YoY Change -23.04% -23.04% 21.12%
LONG-TERM ASSETS
Property, Plant & Equipment $37.24M $37.24M $43.90M
YoY Change -15.25% -15.18% 2.33%
Goodwill
YoY Change
Intangibles
YoY Change
Long-Term Investments $261.0M $261.0M $397.2M
YoY Change -34.28% -34.28% -25.08%
Other Assets $11.00K $11.00K $800.0K
YoY Change -98.64% -98.63%
Total Long-Term Assets $316.5M $316.5M $444.2M
YoY Change -28.76% -28.76% -22.84%
TOTAL ASSETS
Total Short-Term Assets $386.2M $386.2M $501.8M
Total Long-Term Assets $316.5M $316.5M $444.2M
Total Assets $702.6M $702.6M $946.0M
YoY Change -25.72% -25.72% -4.44%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable $26.50M $26.50M $11.30M
YoY Change -26.0% 134.54% 26.97%
Accrued Expenses $26.32M $26.32M $22.00M
YoY Change 19.65% 141.76%
Deferred Revenue
YoY Change
Short-Term Debt $2.345M $2.345M $3.900M
YoY Change -40.12% -39.87% -85.28%
Long-Term Debt Due $10.13M $10.13M $4.800M
YoY Change 110.69% 111.0% 45.45%
Total Short-Term Liabilities $96.89M $96.89M $226.1M
YoY Change -57.16% -57.15% 24.99%
LONG-TERM LIABILITIES
Long-Term Debt $34.40M $34.40M $43.30M
YoY Change -20.56% -20.56% -7.68%
Other Long-Term Liabilities $4.129M $4.129M $2.700M
YoY Change 55.34% 52.93%
Total Long-Term Liabilities $38.53M $38.53M $46.00M
YoY Change -16.17% -16.24% -1.92%
TOTAL LIABILITIES
Total Short-Term Liabilities $96.89M $96.89M $226.1M
Total Long-Term Liabilities $38.53M $38.53M $46.00M
Total Liabilities $155.1M $160.4M $352.5M
YoY Change -56.01% -54.49% 10.09%
SHAREHOLDERS EQUITY
Retained Earnings
YoY Change
Common Stock
YoY Change
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity $542.2M $542.2M $593.5M
YoY Change
Total Liabilities & Shareholders Equity $702.6M $702.6M $946.0M
YoY Change -25.72% -25.72% -4.44%

Cashflow Statement

Concept 2022 Q4 2022 2021
OPERATING ACTIVITIES
Net Income -$22.01M -$37.07M -$60.56M
YoY Change -248.35% -38.8% -1111.02%
Depreciation, Depletion And Amortization $4.599M $8.893M $7.290M
YoY Change 26.38% 21.99% 9.62%
Cash From Operating Activities -$91.54M -$178.8M -$158.3M
YoY Change -1.47% 12.97% 20.06%
INVESTING ACTIVITIES
Capital Expenditures $529.0K $2.176M -$5.660M
YoY Change -118.01% -138.45% 4.43%
Acquisitions
YoY Change
Other Investing Activities -$99.81M -$105.0M $203.0M
YoY Change -216.94% -151.74% -45.11%
Cash From Investing Activities -$100.3M -$107.2M $197.4M
YoY Change -221.75% -154.32% -45.85%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net $38.03M
YoY Change 155.58%
Debt Paid & Issued, Net
YoY Change
Cash From Financing Activities -24.16M -29.83M 22.73M
YoY Change -166.31% -231.22% -41.52%
NET CHANGE
Cash From Operating Activities -91.54M -178.8M -158.3M
Cash From Investing Activities -100.3M -107.2M 197.4M
Cash From Financing Activities -24.16M -29.83M 22.73M
Net Change In Cash -216.0M -315.8M 61.84M
YoY Change -932.8% -610.74% -77.22%
FREE CASH FLOW
Cash From Operating Activities -$91.54M -$178.8M -$158.3M
Capital Expenditures $529.0K $2.176M -$5.660M
Free Cash Flow -$92.07M -$181.0M -$152.6M
YoY Change 2.34% 18.58% 20.73%

Facts In Submission

Frame Concept Type Concept / XBRL Key Value Unit
CY2022 dei Document Fiscal Year Focus
DocumentFiscalYearFocus
2022
CY2022 dei Document Fiscal Period Focus
DocumentFiscalPeriodFocus
FY
CY2022 dei Entity Central Index Key
EntityCentralIndexKey
0001782999
CY2022 dei Amendment Flag
AmendmentFlag
false
CY2022 dei Document Accounting Standard
DocumentAccountingStandard
International Financial Reporting Standards
CY2022 dei Entity Emerging Growth Company
EntityEmergingGrowthCompany
false
CY2022 dei Document Type
DocumentType
20-F
CY2022 dei Document Registration Statement
DocumentRegistrationStatement
false
CY2022 dei Document Annual Report
DocumentAnnualReport
true
CY2022 dei Document Period End Date
DocumentPeriodEndDate
2022-12-31
CY2022 dei Current Fiscal Year End Date
CurrentFiscalYearEndDate
--12-31
CY2022 dei Document Transition Report
DocumentTransitionReport
false
CY2022 dei Document Shell Company Report
DocumentShellCompanyReport
false
CY2022 dei Entity File Number
EntityFileNumber
001-39670
CY2022 dei Entity Registrant Name
EntityRegistrantName
PURETECH HEALTH PLC
CY2022 dei Entity Incorporation State Country Code
EntityIncorporationStateCountryCode
X0
CY2022 dei Entity Address Address Line1
EntityAddressAddressLine1
6 Tide Street
CY2022 dei Entity Address Address Line2
EntityAddressAddressLine2
Suite 400
CY2022 dei Entity Address City Or Town
EntityAddressCityOrTown
Boston
CY2022 dei Entity Address State Or Province
EntityAddressStateOrProvince
MA
CY2022 dei Entity Address Postal Zip Code
EntityAddressPostalZipCode
02210
CY2022 dei Entity Address Country
EntityAddressCountry
US
CY2022Q4 dei Entity Common Stock Shares Outstanding
EntityCommonStockSharesOutstanding
278566306 shares
CY2022 dei Entity Well Known Seasoned Issuer
EntityWellKnownSeasonedIssuer
No
CY2022 dei Entity Voluntary Filers
EntityVoluntaryFilers
No
CY2022 dei Entity Current Reporting Status
EntityCurrentReportingStatus
Yes
CY2022 dei Entity Interactive Data Current
EntityInteractiveDataCurrent
Yes
CY2022 dei Entity Filer Category
EntityFilerCategory
Accelerated Filer
CY2022 dei Icfr Auditor Attestation Flag
IcfrAuditorAttestationFlag
true
CY2022 dei Document Accounting Standard
DocumentAccountingStandard
International Financial Reporting Standards
CY2022 dei Entity Shell Company
EntityShellCompany
false
CY2022 dei Auditor Firm
AuditorFirmId
1118
CY2022 dei Auditor Name
AuditorName
KPMG LLPWe have served as the Group’s auditor since 2015.
CY2022 dei Auditor Location
AuditorLocation
London, United Kingdom
CY2022 ifrs-full Revenue From Contracts With Customers
RevenueFromContractsWithCustomers
2090000 usd
CY2021 ifrs-full Revenue From Contracts With Customers
RevenueFromContractsWithCustomers
9979000 usd
CY2020 ifrs-full Revenue From Contracts With Customers
RevenueFromContractsWithCustomers
8341000 usd
CY2022 ifrs-full Disclosure Of Finance Income Expense Explanatory
DisclosureOfFinanceIncomeExpenseExplanatory
Finance Cost, net <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table shows the breakdown of finance income and costs:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:63.330%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance income</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest income from financial assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,799</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">214 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,183 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance income</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,799</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">214 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,183 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance costs</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contractual interest expense on notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(212)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,031)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(96)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest expense on other borrowings</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,759)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,502)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(496)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest expense on lease liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,982)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,181)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,354)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on foreign currency exchange</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(56)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance cost – contractual</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,939)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,771)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,946)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) from change in fair value of warrant liability</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,740</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,419 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(117)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) from change in fair value of preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">130,825</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,362 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,234)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) from change in fair value of convertible debt</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(502)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(175)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance income/(costs) – fair value accounting</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">137,063</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,606 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,351)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance income/(costs), net</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">138,924</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,050 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,115)</span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>
CY2022 ifrs-full Revenue From Government Grants
RevenueFromGovernmentGrants
13528000 usd
CY2021 ifrs-full Revenue From Government Grants
RevenueFromGovernmentGrants
7409000 usd
CY2020 ifrs-full Revenue From Government Grants
RevenueFromGovernmentGrants
3427000 usd
CY2022 ifrs-full Revenue
Revenue
15618000 usd
CY2021 ifrs-full Revenue
Revenue
17388000 usd
CY2020 ifrs-full Revenue
Revenue
11768000 usd
CY2022 ifrs-full General And Administrative Expense
GeneralAndAdministrativeExpense
60991000 usd
CY2021 ifrs-full General And Administrative Expense
GeneralAndAdministrativeExpense
57199000 usd
CY2020 ifrs-full General And Administrative Expense
GeneralAndAdministrativeExpense
49440000 usd
CY2022 ifrs-full Research And Development Expense
ResearchAndDevelopmentExpense
152433000 usd
CY2021 ifrs-full Research And Development Expense
ResearchAndDevelopmentExpense
110471000 usd
CY2020 ifrs-full Research And Development Expense
ResearchAndDevelopmentExpense
81859000 usd
CY2022 ifrs-full Profit Loss From Operating Activities
ProfitLossFromOperatingActivities
-197807000 usd
CY2021 ifrs-full Profit Loss From Operating Activities
ProfitLossFromOperatingActivities
-150282000 usd
CY2020 ifrs-full Profit Loss From Operating Activities
ProfitLossFromOperatingActivities
-119531000 usd
CY2022 ifrs-full Gains Losses Recognised When Control In Subsidiary Is Lost
GainsLossesRecognisedWhenControlInSubsidiaryIsLost
27251000 usd
CY2021 ifrs-full Gains Losses Recognised When Control In Subsidiary Is Lost
GainsLossesRecognisedWhenControlInSubsidiaryIsLost
0 usd
CY2020 ifrs-full Gains Losses Recognised When Control In Subsidiary Is Lost
GainsLossesRecognisedWhenControlInSubsidiaryIsLost
0 usd
CY2022 ifrs-full Gains Losses Recognised In Profit Or Loss Fair Value Measurement Assets
GainsLossesRecognisedInProfitOrLossFairValueMeasurementAssets
-32060000 usd
CY2021 ifrs-full Gains Losses Recognised In Profit Or Loss Fair Value Measurement Assets
GainsLossesRecognisedInProfitOrLossFairValueMeasurementAssets
179316000 usd
CY2020 ifrs-full Gains Losses Recognised In Profit Or Loss Fair Value Measurement Assets
GainsLossesRecognisedInProfitOrLossFairValueMeasurementAssets
232674000 usd
CY2022 ifrs-full Losses On Disposals Of Investments
LossesOnDisposalsOfInvestments
29303000 usd
CY2021 ifrs-full Losses On Disposals Of Investments
LossesOnDisposalsOfInvestments
20925000 usd
CY2020 ifrs-full Losses On Disposals Of Investments
LossesOnDisposalsOfInvestments
54976000 usd
CY2022 ifrs-full Other Gains Losses
OtherGainsLosses
8131000 usd
CY2021 ifrs-full Other Gains Losses
OtherGainsLosses
1592000 usd
CY2020 ifrs-full Other Gains Losses
OtherGainsLosses
1035000 usd
CY2022 ifrs-full Other Operating Income Expense
OtherOperatingIncomeExpense
-25981000 usd
CY2021 ifrs-full Other Operating Income Expense
OtherOperatingIncomeExpense
159983000 usd
CY2020 ifrs-full Other Operating Income Expense
OtherOperatingIncomeExpense
178732000 usd
CY2022 ifrs-full Finance Income
FinanceIncome
5799000 usd
CY2021 ifrs-full Finance Income
FinanceIncome
214000 usd
CY2020 ifrs-full Finance Income
FinanceIncome
1183000 usd
CY2022 ifrs-full Finance Costs
FinanceCosts
3939000 usd
CY2021 ifrs-full Finance Costs
FinanceCosts
4771000 usd
CY2020 ifrs-full Finance Costs
FinanceCosts
2946000 usd
CY2022 ifrs-full Gains Losses Recognised In Profit Or Loss Fair Value Measurement Liabilities
GainsLossesRecognisedInProfitOrLossFairValueMeasurementLiabilities
137063000 usd
CY2021 ifrs-full Gains Losses Recognised In Profit Or Loss Fair Value Measurement Liabilities
GainsLossesRecognisedInProfitOrLossFairValueMeasurementLiabilities
9606000 usd
CY2020 ifrs-full Gains Losses Recognised In Profit Or Loss Fair Value Measurement Liabilities
GainsLossesRecognisedInProfitOrLossFairValueMeasurementLiabilities
-4351000 usd
CY2022 ifrs-full Finance Income Cost
FinanceIncomeCost
138924000 usd
CY2021 ifrs-full Finance Income Cost
FinanceIncomeCost
5050000 usd
CY2020 ifrs-full Finance Income Cost
FinanceIncomeCost
-6115000 usd
CY2022 ifrs-full Share Of Profit Loss Of Associates And Joint Ventures Accounted For Using Equity Method
ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod
-27749000 usd
CY2021 ifrs-full Share Of Profit Loss Of Associates And Joint Ventures Accounted For Using Equity Method
ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod
-73703000 usd
CY2020 ifrs-full Share Of Profit Loss Of Associates And Joint Ventures Accounted For Using Equity Method
ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod
-34117000 usd
CY2022 ptv Gain Loss Recognized On Dilution Of Ownership Interest In Associate
GainLossRecognizedOnDilutionOfOwnershipInterestInAssociate
28220000 usd
CY2021 ptv Gain Loss Recognized On Dilution Of Ownership Interest In Associate
GainLossRecognizedOnDilutionOfOwnershipInterestInAssociate
0 usd
CY2020 ptv Gain Loss Recognized On Dilution Of Ownership Interest In Associate
GainLossRecognizedOnDilutionOfOwnershipInterestInAssociate
0 usd
CY2022 ifrs-full Impairment Loss Recognised In Profit Or Loss
ImpairmentLossRecognisedInProfitOrLoss
8390000 usd
CY2021 ifrs-full Impairment Loss Recognised In Profit Or Loss
ImpairmentLossRecognisedInProfitOrLoss
0 usd
CY2020 ifrs-full Impairment Loss Recognised In Profit Or Loss
ImpairmentLossRecognisedInProfitOrLoss
0 usd
CY2022 ifrs-full Profit Loss Before Tax
ProfitLossBeforeTax
-92783000 usd
CY2021 ifrs-full Profit Loss Before Tax
ProfitLossBeforeTax
-58953000 usd
CY2020 ifrs-full Profit Loss Before Tax
ProfitLossBeforeTax
18969000 usd
CY2022 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
-55719000 usd
CY2021 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
3756000 usd
CY2020 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
14401000 usd
CY2022 ifrs-full Profit Loss
ProfitLoss
-37065000 usd
CY2021 ifrs-full Profit Loss
ProfitLoss
-62709000 usd
CY2020 ifrs-full Profit Loss
ProfitLoss
4568000 usd
CY2022 ifrs-full Gains Losses On Exchange Differences On Translation Before Tax
GainsLossesOnExchangeDifferencesOnTranslationBeforeTax
-166000 usd
CY2021 ifrs-full Gains Losses On Exchange Differences On Translation Before Tax
GainsLossesOnExchangeDifferencesOnTranslationBeforeTax
0 usd
CY2020 ifrs-full Gains Losses On Exchange Differences On Translation Before Tax
GainsLossesOnExchangeDifferencesOnTranslationBeforeTax
469000 usd
CY2022 ifrs-full Other Comprehensive Income Before Tax Gains Losses From Investments In Equity Instruments
OtherComprehensiveIncomeBeforeTaxGainsLossesFromInvestmentsInEquityInstruments
-213000 usd
CY2021 ifrs-full Other Comprehensive Income Before Tax Gains Losses From Investments In Equity Instruments
OtherComprehensiveIncomeBeforeTaxGainsLossesFromInvestmentsInEquityInstruments
0 usd
CY2020 ifrs-full Other Comprehensive Income Before Tax Gains Losses From Investments In Equity Instruments
OtherComprehensiveIncomeBeforeTaxGainsLossesFromInvestmentsInEquityInstruments
0 usd
CY2022 ifrs-full Other Comprehensive Income
OtherComprehensiveIncome
-379000 usd
CY2021 ifrs-full Other Comprehensive Income
OtherComprehensiveIncome
0 usd
CY2020 ifrs-full Other Comprehensive Income
OtherComprehensiveIncome
469000 usd
CY2022 ifrs-full Comprehensive Income
ComprehensiveIncome
-37444000 usd
CY2021 ifrs-full Comprehensive Income
ComprehensiveIncome
-62709000 usd
CY2020 ifrs-full Comprehensive Income
ComprehensiveIncome
5037000 usd
CY2022 ifrs-full Profit Loss Attributable To Owners Of Parent
ProfitLossAttributableToOwnersOfParent
-50354000 usd
CY2021 ifrs-full Profit Loss Attributable To Owners Of Parent
ProfitLossAttributableToOwnersOfParent
-60558000 usd
CY2020 ifrs-full Profit Loss Attributable To Owners Of Parent
ProfitLossAttributableToOwnersOfParent
5985000 usd
CY2022 ifrs-full Profit Loss Attributable To Noncontrolling Interests
ProfitLossAttributableToNoncontrollingInterests
13290000 usd
CY2021 ifrs-full Profit Loss Attributable To Noncontrolling Interests
ProfitLossAttributableToNoncontrollingInterests
-2151000 usd
CY2020 ifrs-full Profit Loss Attributable To Noncontrolling Interests
ProfitLossAttributableToNoncontrollingInterests
-1417000 usd
CY2022 ifrs-full Profit Loss
ProfitLoss
-37065000 usd
CY2021 ifrs-full Profit Loss
ProfitLoss
-62709000 usd
CY2020 ifrs-full Profit Loss
ProfitLoss
4568000 usd
CY2022 ifrs-full Comprehensive Income Attributable To Owners Of Parent
ComprehensiveIncomeAttributableToOwnersOfParent
-50733000 usd
CY2021 ifrs-full Comprehensive Income Attributable To Owners Of Parent
ComprehensiveIncomeAttributableToOwnersOfParent
-60558000 usd
CY2020 ifrs-full Comprehensive Income Attributable To Owners Of Parent
ComprehensiveIncomeAttributableToOwnersOfParent
6454000 usd
CY2022 ifrs-full Comprehensive Income Attributable To Noncontrolling Interests
ComprehensiveIncomeAttributableToNoncontrollingInterests
13290000 usd
CY2021 ifrs-full Comprehensive Income Attributable To Noncontrolling Interests
ComprehensiveIncomeAttributableToNoncontrollingInterests
-2151000 usd
CY2020 ifrs-full Comprehensive Income Attributable To Noncontrolling Interests
ComprehensiveIncomeAttributableToNoncontrollingInterests
-1417000 usd
CY2022 ifrs-full Comprehensive Income
ComprehensiveIncome
-37444000 usd
CY2021 ifrs-full Comprehensive Income
ComprehensiveIncome
-62709000 usd
CY2020 ifrs-full Comprehensive Income
ComprehensiveIncome
5037000 usd
CY2022 ifrs-full Basic Earnings Loss Per Share
BasicEarningsLossPerShare
-0.18
CY2021 ifrs-full Basic Earnings Loss Per Share
BasicEarningsLossPerShare
-0.21
CY2020 ifrs-full Basic Earnings Loss Per Share
BasicEarningsLossPerShare
0.02
CY2022 ifrs-full Diluted Earnings Loss Per Share
DilutedEarningsLossPerShare
-0.18
CY2021 ifrs-full Diluted Earnings Loss Per Share
DilutedEarningsLossPerShare
-0.21
CY2020 ifrs-full Diluted Earnings Loss Per Share
DilutedEarningsLossPerShare
0.02
CY2022Q4 ifrs-full Property Plant And Equipment
PropertyPlantAndEquipment
22957000 usd
CY2021Q4 ifrs-full Property Plant And Equipment
PropertyPlantAndEquipment
26771000 usd
CY2022Q4 ifrs-full Rightofuse Assets
RightofuseAssets
14281000 usd
CY2021Q4 ifrs-full Rightofuse Assets
RightofuseAssets
17166000 usd
CY2022Q4 ifrs-full Intangible Assets Other Than Goodwill
IntangibleAssetsOtherThanGoodwill
831000 usd
CY2021Q4 ifrs-full Intangible Assets Other Than Goodwill
IntangibleAssetsOtherThanGoodwill
987000 usd
CY2022Q4 ifrs-full Noncurrent Financial Assets At Fair Value Through Profit Or Loss
NoncurrentFinancialAssetsAtFairValueThroughProfitOrLoss
251892000 usd
CY2021Q4 ifrs-full Noncurrent Financial Assets At Fair Value Through Profit Or Loss
NoncurrentFinancialAssetsAtFairValueThroughProfitOrLoss
397179000 usd
CY2022Q4 ifrs-full Investments In Associates
InvestmentsInAssociates
9147000 usd
CY2021Q4 ifrs-full Investments In Associates
InvestmentsInAssociates
0 usd
CY2022Q4 ifrs-full Noncurrent Receivables Due From Associates
NoncurrentReceivablesDueFromAssociates
16501000 usd
CY2021Q4 ifrs-full Noncurrent Receivables Due From Associates
NoncurrentReceivablesDueFromAssociates
0 usd
CY2022Q4 ifrs-full Noncurrent Finance Lease Receivables
NoncurrentFinanceLeaseReceivables
835000 usd
CY2021Q4 ifrs-full Noncurrent Finance Lease Receivables
NoncurrentFinanceLeaseReceivables
1285000 usd
CY2022Q4 ifrs-full Other Noncurrent Assets
OtherNoncurrentAssets
10000 usd
CY2021Q4 ifrs-full Other Noncurrent Assets
OtherNoncurrentAssets
810000 usd
CY2022Q4 ifrs-full Noncurrent Assets
NoncurrentAssets
316454000 usd
CY2021Q4 ifrs-full Noncurrent Assets
NoncurrentAssets
444197000 usd
CY2022Q4 ifrs-full Trade And Other Current Receivables
TradeAndOtherCurrentReceivables
11867000 usd
CY2021Q4 ifrs-full Trade And Other Current Receivables
TradeAndOtherCurrentReceivables
3174000 usd
CY2022Q4 ifrs-full Current Tax Assets Current
CurrentTaxAssetsCurrent
10040000 usd
CY2021Q4 ifrs-full Current Tax Assets Current
CurrentTaxAssetsCurrent
4514000 usd
CY2022Q4 ifrs-full Current Prepaid Expenses
CurrentPrepaidExpenses
11617000 usd
CY2021Q4 ifrs-full Current Prepaid Expenses
CurrentPrepaidExpenses
10755000 usd
CY2022Q4 ifrs-full Current Finance Lease Receivables
CurrentFinanceLeaseReceivables
450000 usd
CY2021Q4 ifrs-full Current Finance Lease Receivables
CurrentFinanceLeaseReceivables
415000 usd
CY2022Q4 ifrs-full Restricted Cash And Cash Equivalents
RestrictedCashAndCashEquivalents
2124000 usd
CY2021Q4 ifrs-full Restricted Cash And Cash Equivalents
RestrictedCashAndCashEquivalents
2124000 usd
CY2022Q4 ifrs-full Current Receivables Due From Associates
CurrentReceivablesDueFromAssociates
0 usd
CY2021Q4 ifrs-full Current Receivables Due From Associates
CurrentReceivablesDueFromAssociates
15120000 usd
CY2022Q4 ptv Short Term Investments
ShortTermInvestments
200229000 usd
CY2021Q4 ptv Short Term Investments
ShortTermInvestments
0 usd
CY2022Q4 ifrs-full Cash And Cash Equivalents
CashAndCashEquivalents
149866000 usd
CY2021Q4 ifrs-full Cash And Cash Equivalents
CashAndCashEquivalents
465708000 usd
CY2022Q4 ifrs-full Current Assets
CurrentAssets
386192000 usd
CY2021Q4 ifrs-full Current Assets
CurrentAssets
501809000 usd
CY2022Q4 ifrs-full Assets
Assets
702647000 usd
CY2021Q4 ifrs-full Assets
Assets
946006000 usd
CY2022Q4 ifrs-full Issued Capital
IssuedCapital
5455000 usd
CY2021Q4 ifrs-full Issued Capital
IssuedCapital
5444000 usd
CY2022Q4 ifrs-full Share Premium
SharePremium
289624000 usd
CY2021Q4 ifrs-full Share Premium
SharePremium
289303000 usd
CY2022Q4 ifrs-full Treasury Shares
TreasuryShares
26492000 usd
CY2021Q4 ifrs-full Treasury Shares
TreasuryShares
0 usd
CY2022Q4 ifrs-full Merger Reserve
MergerReserve
138506000 usd
CY2021Q4 ifrs-full Merger Reserve
MergerReserve
138506000 usd
CY2022Q4 ifrs-full Reserve Of Exchange Differences On Translation
ReserveOfExchangeDifferencesOnTranslation
89000 usd
CY2021Q4 ifrs-full Reserve Of Exchange Differences On Translation
ReserveOfExchangeDifferencesOnTranslation
469000 usd
CY2022Q4 ifrs-full Other Reserves
OtherReserves
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CY2021Q4 ifrs-full Other Reserves
OtherReserves
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CY2022Q4 ifrs-full Retained Earnings
RetainedEarnings
149516000 usd
CY2021Q4 ifrs-full Retained Earnings
RetainedEarnings
199871000 usd
CY2022Q4 ifrs-full Equity Attributable To Owners Of Parent
EquityAttributableToOwnersOfParent
542220000 usd
CY2021Q4 ifrs-full Equity Attributable To Owners Of Parent
EquityAttributableToOwnersOfParent
593515000 usd
CY2022Q4 ifrs-full Noncontrolling Interests
NoncontrollingInterests
5369000 usd
CY2021Q4 ifrs-full Noncontrolling Interests
NoncontrollingInterests
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CY2022Q4 ifrs-full Equity
Equity
547589000 usd
CY2021Q4 ifrs-full Equity
Equity
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CY2022Q4 ifrs-full Deferred Tax Liabilities
DeferredTaxLiabilities
19645000 usd
CY2021Q4 ifrs-full Deferred Tax Liabilities
DeferredTaxLiabilities
89765000 usd
CY2022Q4 ifrs-full Noncurrent Lease Liabilities
NoncurrentLeaseLiabilities
24155000 usd
CY2021Q4 ifrs-full Noncurrent Lease Liabilities
NoncurrentLeaseLiabilities
29040000 usd
CY2022Q4 ifrs-full Longterm Borrowings
LongtermBorrowings
10244000 usd
CY2021Q4 ifrs-full Longterm Borrowings
LongtermBorrowings
14261000 usd
CY2022Q4 ptv Non Current Liabilities From Share Based Payment Transactions
NonCurrentLiabilitiesFromShareBasedPaymentTransactions
4128000 usd
CY2021Q4 ptv Non Current Liabilities From Share Based Payment Transactions
NonCurrentLiabilitiesFromShareBasedPaymentTransactions
2659000 usd
CY2022Q4 ifrs-full Noncurrent Liabilities
NoncurrentLiabilities
58172000 usd
CY2021Q4 ifrs-full Noncurrent Liabilities
NoncurrentLiabilities
135725000 usd
CY2022Q4 ifrs-full Current Government Grants
CurrentGovernmentGrants
2185000 usd
CY2021Q4 ifrs-full Current Government Grants
CurrentGovernmentGrants
65000 usd
CY2022Q4 ifrs-full Current Lease Liabilities
CurrentLeaseLiabilities
4972000 usd
CY2021Q4 ifrs-full Current Lease Liabilities
CurrentLeaseLiabilities
3950000 usd
CY2022Q4 ifrs-full Trade And Other Current Payables
TradeAndOtherCurrentPayables
54840000 usd
CY2021Q4 ifrs-full Trade And Other Current Payables
TradeAndOtherCurrentPayables
35817000 usd
CY2022Q4 ifrs-full Notes And Debentures Issued
NotesAndDebenturesIssued
2345000 usd
CY2021Q4 ifrs-full Notes And Debentures Issued
NotesAndDebenturesIssued
4641000 usd
CY2022Q4 ifrs-full Current Derivative Financial Liabilities
CurrentDerivativeFinancialLiabilities
47000 usd
CY2021Q4 ifrs-full Current Derivative Financial Liabilities
CurrentDerivativeFinancialLiabilities
6787000 usd
CY2022Q4 ptv Preferred Share Liability
PreferredShareLiability
27339000 usd
CY2021Q4 ptv Preferred Share Liability
PreferredShareLiability
174017000 usd
CY2022Q4 ifrs-full Current Portion Of Longterm Borrowings
CurrentPortionOfLongtermBorrowings
5156000 usd
CY2021Q4 ifrs-full Current Portion Of Longterm Borrowings
CurrentPortionOfLongtermBorrowings
857000 usd
CY2022Q4 ifrs-full Current Liabilities
CurrentLiabilities
96885000 usd
CY2021Q4 ifrs-full Current Liabilities
CurrentLiabilities
226135000 usd
CY2022Q4 ifrs-full Liabilities
Liabilities
155057000 usd
CY2021Q4 ifrs-full Liabilities
Liabilities
361859000 usd
CY2022Q4 ifrs-full Equity And Liabilities
EquityAndLiabilities
702647000 usd
CY2021Q4 ifrs-full Equity And Liabilities
EquityAndLiabilities
946006000 usd
CY2019Q4 ifrs-full Equity
Equity
650398000 usd
CY2020 ifrs-full Profit Loss
ProfitLoss
4568000 usd
CY2020 ifrs-full Other Comprehensive Income
OtherComprehensiveIncome
469000 usd
CY2020 ifrs-full Comprehensive Income
ComprehensiveIncome
5037000 usd
CY2020 ifrs-full Increase Decrease Through Exercise Of Options
IncreaseDecreaseThroughExerciseOfOptions
1036000 usd
CY2020 ifrs-full Decrease Increase Through Tax On Sharebased Payment Transactions
DecreaseIncreaseThroughTaxOnSharebasedPaymentTransactions
684000 usd
CY2020 ifrs-full Increase Decrease Through Sharebased Payment Transactions
IncreaseDecreaseThroughSharebasedPaymentTransactions
10627000 usd
CY2020 ptv Increase Decrease Through Settlement Of Restricted Stock Units
IncreaseDecreaseThroughSettlementOfRestrictedStockUnits
-12888000 usd
CY2020 ifrs-full Increase Decrease Through Transfers And Other Changes Equity
IncreaseDecreaseThroughTransfersAndOtherChangesEquity
13000 usd
CY2020Q4 ifrs-full Equity
Equity
653539000 usd
CY2021 ifrs-full Profit Loss
ProfitLoss
-62709000 usd
CY2021 ifrs-full Comprehensive Income
ComprehensiveIncome
-62709000 usd
CY2021 ifrs-full Increase Decrease Through Exercise Of Options
IncreaseDecreaseThroughExerciseOfOptions
352000 usd
CY2021 ifrs-full Decrease Increase Through Tax On Sharebased Payment Transactions
DecreaseIncreaseThroughTaxOnSharebasedPaymentTransactions
-615000 usd
CY2021 ifrs-full Increase Decrease Through Sharebased Payment Transactions
IncreaseDecreaseThroughSharebasedPaymentTransactions
13361000 usd
CY2021 ptv Increase Decrease Through Settlement Of Restricted Stock Units
IncreaseDecreaseThroughSettlementOfRestrictedStockUnits
-10749000 usd
CY2021 ptv Increase Decrease In Reclassification Of Equity Settled Awards Into Liability Awards
IncreaseDecreaseInReclassificationOfEquitySettledAwardsIntoLiabilityAwards
-6773000 usd
CY2021 ptv Increase Decrease Through Vesting Of Share Based Awards And Net Share Exercise Equity
IncreaseDecreaseThroughVestingOfShareBasedAwardsAndNetShareExerciseEquity
-2582000 usd
CY2021 ifrs-full Increase Decrease Through Acquisition Of Subsidiary
IncreaseDecreaseThroughAcquisitionOfSubsidiary
-968000 usd
CY2021 ptv Increase Decrease Through Nci Exercise Of Share Based Awards In Subsidiaries
IncreaseDecreaseThroughNCIExerciseOfShareBasedAwardsInSubsidiaries
66000 usd
CY2021 ifrs-full Increase Decrease Through Transfers And Other Changes Equity
IncreaseDecreaseThroughTransfersAndOtherChangesEquity
-6000 usd
CY2021Q4 ifrs-full Equity
Equity
584147000 usd
CY2022 ifrs-full Profit Loss
ProfitLoss
-37065000 usd
CY2022 ifrs-full Other Comprehensive Income
OtherComprehensiveIncome
-379000 usd
CY2022 ifrs-full Comprehensive Income
ComprehensiveIncome
-37444000 usd
CY2022 ifrs-full Increase Decrease Through Change In Equity Of Subsidiaries
IncreaseDecreaseThroughChangeInEquityOfSubsidiaries
11904000 usd
CY2022 ifrs-full Increase Decrease Through Exercise Of Options
IncreaseDecreaseThroughExerciseOfOptions
332000 usd
CY2022 ptv Increase Decrease Through Revaluation Of Deferred Tax Assets Related To Share Based Payment Transactions Equity
IncreaseDecreaseThroughRevaluationOfDeferredTaxAssetsRelatedToShareBasedPaymentTransactionsEquity
45000 usd
CY2022 ifrs-full Purchase Of Treasury Shares
PurchaseOfTreasuryShares
26492000 usd
CY2022 ifrs-full Increase Decrease Through Sharebased Payment Transactions
IncreaseDecreaseThroughSharebasedPaymentTransactions
13567000 usd
CY2022 ptv Ordinary Shares Issued To Settle Share Based Payment Awards
OrdinarySharesIssuedToSettleShareBasedPaymentAwards
1528000 usd
CY2022 ptv Increase Decrease Through Nci Exercise Of Share Based Awards In Subsidiaries
IncreaseDecreaseThroughNCIExerciseOfShareBasedAwardsInSubsidiaries
7000 usd
CY2022 ifrs-full Increase Decrease Through Transfers And Other Changes Equity
IncreaseDecreaseThroughTransfersAndOtherChangesEquity
-4000 usd
CY2022Q4 ifrs-full Equity
Equity
547589000 usd
CY2022 ifrs-full Profit Loss
ProfitLoss
-37065000 usd
CY2021 ifrs-full Profit Loss
ProfitLoss
-62709000 usd
CY2020 ifrs-full Profit Loss
ProfitLoss
4568000 usd
CY2022 ifrs-full Adjustments For Depreciation And Amortisation Expense
AdjustmentsForDepreciationAndAmortisationExpense
8893000 usd
CY2021 ifrs-full Adjustments For Depreciation And Amortisation Expense
AdjustmentsForDepreciationAndAmortisationExpense
7287000 usd
CY2020 ifrs-full Adjustments For Depreciation And Amortisation Expense
AdjustmentsForDepreciationAndAmortisationExpense
6645000 usd
CY2022 ifrs-full Adjustments For Sharebased Payments
AdjustmentsForSharebasedPayments
14698000 usd
CY2021 ifrs-full Adjustments For Sharebased Payments
AdjustmentsForSharebasedPayments
13950000 usd
CY2020 ifrs-full Adjustments For Sharebased Payments
AdjustmentsForSharebasedPayments
10718000 usd
CY2022 ifrs-full Adjustments For Fair Value Gains Losses
AdjustmentsForFairValueGainsLosses
32060000 usd
CY2021 ifrs-full Adjustments For Fair Value Gains Losses
AdjustmentsForFairValueGainsLosses
-179316000 usd
CY2020 ifrs-full Adjustments For Fair Value Gains Losses
AdjustmentsForFairValueGainsLosses
-232674000 usd
CY2022 ifrs-full Adjustments For Losses Gains On Disposal Of Noncurrent Assets
AdjustmentsForLossesGainsOnDisposalOfNoncurrentAssets
29303000 usd
CY2021 ifrs-full Adjustments For Losses Gains On Disposal Of Noncurrent Assets
AdjustmentsForLossesGainsOnDisposalOfNoncurrentAssets
20925000 usd
CY2020 ifrs-full Adjustments For Losses Gains On Disposal Of Noncurrent Assets
AdjustmentsForLossesGainsOnDisposalOfNoncurrentAssets
54976000 usd
CY2022 ptv Gain Loss Recognized On Dilution Of Ownership Interest In Associate
GainLossRecognizedOnDilutionOfOwnershipInterestInAssociate
28220000 usd
CY2021 ptv Gain Loss Recognized On Dilution Of Ownership Interest In Associate
GainLossRecognizedOnDilutionOfOwnershipInterestInAssociate
0 usd
CY2020 ptv Gain Loss Recognized On Dilution Of Ownership Interest In Associate
GainLossRecognizedOnDilutionOfOwnershipInterestInAssociate
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CY2022 ifrs-full Impairment Loss Recognised In Profit Or Loss
ImpairmentLossRecognisedInProfitOrLoss
8390000 usd
CY2021 ifrs-full Impairment Loss Recognised In Profit Or Loss
ImpairmentLossRecognisedInProfitOrLoss
0 usd
CY2020 ifrs-full Impairment Loss Recognised In Profit Or Loss
ImpairmentLossRecognisedInProfitOrLoss
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CY2022 ifrs-full Adjustments For Gain Loss On Disposal Of Investments In Subsidiaries Joint Ventures And Associates
AdjustmentsForGainLossOnDisposalOfInvestmentsInSubsidiariesJointVenturesAndAssociates
27251000 usd
CY2021 ifrs-full Adjustments For Gain Loss On Disposal Of Investments In Subsidiaries Joint Ventures And Associates
AdjustmentsForGainLossOnDisposalOfInvestmentsInSubsidiariesJointVenturesAndAssociates
0 usd
CY2020 ifrs-full Adjustments For Gain Loss On Disposal Of Investments In Subsidiaries Joint Ventures And Associates
AdjustmentsForGainLossOnDisposalOfInvestmentsInSubsidiariesJointVenturesAndAssociates
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CY2022 ifrs-full Share Of Profit Loss Of Associates And Joint Ventures Accounted For Using Equity Method
ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod
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CY2021 ifrs-full Share Of Profit Loss Of Associates And Joint Ventures Accounted For Using Equity Method
ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod
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CY2020 ifrs-full Share Of Profit Loss Of Associates And Joint Ventures Accounted For Using Equity Method
ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod
-34117000 usd
CY2022 ifrs-full Adjustments For Gains Losses On Change In Fair Value Of Derivatives
AdjustmentsForGainsLossesOnChangeInFairValueOfDerivatives
8163000 usd
CY2021 ifrs-full Adjustments For Gains Losses On Change In Fair Value Of Derivatives
AdjustmentsForGainsLossesOnChangeInFairValueOfDerivatives
800000 usd
CY2020 ifrs-full Adjustments For Gains Losses On Change In Fair Value Of Derivatives
AdjustmentsForGainsLossesOnChangeInFairValueOfDerivatives
0 usd
CY2022 ifrs-full Adjustments For Gain Loss On Disposals Property Plant And Equipment
AdjustmentsForGainLossOnDisposalsPropertyPlantAndEquipment
-138000 usd
CY2021 ifrs-full Adjustments For Gain Loss On Disposals Property Plant And Equipment
AdjustmentsForGainLossOnDisposalsPropertyPlantAndEquipment
-53000 usd
CY2020 ifrs-full Adjustments For Gain Loss On Disposals Property Plant And Equipment
AdjustmentsForGainLossOnDisposalsPropertyPlantAndEquipment
-66000 usd
CY2022 ifrs-full Adjustments For Income Tax Expense
AdjustmentsForIncomeTaxExpense
-55719000 usd
CY2021 ifrs-full Adjustments For Income Tax Expense
AdjustmentsForIncomeTaxExpense
3756000 usd
CY2020 ifrs-full Adjustments For Income Tax Expense
AdjustmentsForIncomeTaxExpense
14402000 usd
CY2022 ptv Adjustments For Finance Costs Income
AdjustmentsForFinanceCostsIncome
-138924000 usd
CY2021 ptv Adjustments For Finance Costs Income
AdjustmentsForFinanceCostsIncome
-5050000 usd
CY2020 ptv Adjustments For Finance Costs Income
AdjustmentsForFinanceCostsIncome
6114000 usd
CY2022 ifrs-full Adjustments For Decrease Increase In Trade And Other Receivables
AdjustmentsForDecreaseIncreaseInTradeAndOtherReceivables
-7734000 usd
CY2021 ifrs-full Adjustments For Decrease Increase In Trade And Other Receivables
AdjustmentsForDecreaseIncreaseInTradeAndOtherReceivables
-617000 usd
CY2020 ifrs-full Adjustments For Decrease Increase In Trade And Other Receivables
AdjustmentsForDecreaseIncreaseInTradeAndOtherReceivables
-529000 usd
CY2022 ifrs-full Adjustments For Decrease Increase In Other Current Assets
AdjustmentsForDecreaseIncreaseInOtherCurrentAssets
-862000 usd
CY2021 ifrs-full Adjustments For Decrease Increase In Other Current Assets
AdjustmentsForDecreaseIncreaseInOtherCurrentAssets
-5350000 usd
CY2020 ifrs-full Adjustments For Decrease Increase In Other Current Assets
AdjustmentsForDecreaseIncreaseInOtherCurrentAssets
-3371000 usd
CY2022 ptv Adjustments For Increase Decrease In Deferred Revenue
AdjustmentsForIncreaseDecreaseInDeferredRevenue
2123000 usd
CY2021 ptv Adjustments For Increase Decrease In Deferred Revenue
AdjustmentsForIncreaseDecreaseInDeferredRevenue
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CY2020 ptv Adjustments For Increase Decrease In Deferred Revenue
AdjustmentsForIncreaseDecreaseInDeferredRevenue
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CY2022 ifrs-full Adjustments For Increase Decrease In Trade Account Payable
AdjustmentsForIncreaseDecreaseInTradeAccountPayable
22033000 usd
CY2021 ifrs-full Adjustments For Increase Decrease In Trade Account Payable
AdjustmentsForIncreaseDecreaseInTradeAccountPayable
8338000 usd
CY2020 ifrs-full Adjustments For Increase Decrease In Trade Account Payable
AdjustmentsForIncreaseDecreaseInTradeAccountPayable
605000 usd
CY2022 ifrs-full Other Inflows Outflows Of Cash Classified As Operating Activities
OtherInflowsOutflowsOfCashClassifiedAsOperatingActivities
359000 usd
CY2021 ifrs-full Other Inflows Outflows Of Cash Classified As Operating Activities
OtherInflowsOutflowsOfCashClassifiedAsOperatingActivities
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CY2020 ifrs-full Other Inflows Outflows Of Cash Classified As Operating Activities
OtherInflowsOutflowsOfCashClassifiedAsOperatingActivities
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CY2022 ifrs-full Income Taxes Paid Refund Classified As Operating Activities
IncomeTaxesPaidRefundClassifiedAsOperatingActivities
20696000 usd
CY2021 ifrs-full Income Taxes Paid Refund Classified As Operating Activities
IncomeTaxesPaidRefundClassifiedAsOperatingActivities
27766000 usd
CY2020 ifrs-full Income Taxes Paid Refund Classified As Operating Activities
IncomeTaxesPaidRefundClassifiedAsOperatingActivities
20737000 usd
CY2022 ifrs-full Interest Received Classified As Operating Activities
InterestReceivedClassifiedAsOperatingActivities
3460000 usd
CY2021 ifrs-full Interest Received Classified As Operating Activities
InterestReceivedClassifiedAsOperatingActivities
214000 usd
CY2020 ifrs-full Interest Received Classified As Operating Activities
InterestReceivedClassifiedAsOperatingActivities
1155000 usd
CY2022 ifrs-full Interest Paid Classified As Operating Activities
InterestPaidClassifiedAsOperatingActivities
3366000 usd
CY2021 ifrs-full Interest Paid Classified As Operating Activities
InterestPaidClassifiedAsOperatingActivities
3382000 usd
CY2020 ifrs-full Interest Paid Classified As Operating Activities
InterestPaidClassifiedAsOperatingActivities
2651000 usd
CY2022 ifrs-full Cash Flows From Used In Operating Activities
CashFlowsFromUsedInOperatingActivities
-178792000 usd
CY2021 ifrs-full Cash Flows From Used In Operating Activities
CashFlowsFromUsedInOperatingActivities
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CY2020 ifrs-full Cash Flows From Used In Operating Activities
CashFlowsFromUsedInOperatingActivities
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CY2022 ifrs-full Purchase Of Property Plant And Equipment Classified As Investing Activities
PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities
2176000 usd
CY2021 ifrs-full Purchase Of Property Plant And Equipment Classified As Investing Activities
PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities
5571000 usd
CY2020 ifrs-full Purchase Of Property Plant And Equipment Classified As Investing Activities
PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities
5170000 usd
CY2022 ifrs-full Proceeds From Sales Of Property Plant And Equipment Classified As Investing Activities
ProceedsFromSalesOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities
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CY2021 ifrs-full Proceeds From Sales Of Property Plant And Equipment Classified As Investing Activities
ProceedsFromSalesOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities
30000 usd
CY2020 ifrs-full Proceeds From Sales Of Property Plant And Equipment Classified As Investing Activities
ProceedsFromSalesOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities
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CY2022 ifrs-full Purchase Of Intangible Assets Classified As Investing Activities
PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities
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CY2021 ifrs-full Purchase Of Intangible Assets Classified As Investing Activities
PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities
90000 usd
CY2020 ifrs-full Purchase Of Intangible Assets Classified As Investing Activities
PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities
254000 usd
CY2022 ifrs-full Purchase Of Interests In Associates
PurchaseOfInterestsInAssociates
19961000 usd
CY2021 ifrs-full Purchase Of Interests In Associates
PurchaseOfInterestsInAssociates
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CY2020 ifrs-full Purchase Of Interests In Associates
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CY2022 ifrs-full Purchase Of Investments Other Than Investments Accounted For Using Equity Method
PurchaseOfInvestmentsOtherThanInvestmentsAccountedForUsingEquityMethod
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CY2021 ifrs-full Purchase Of Investments Other Than Investments Accounted For Using Equity Method
PurchaseOfInvestmentsOtherThanInvestmentsAccountedForUsingEquityMethod
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CY2020 ifrs-full Purchase Of Investments Other Than Investments Accounted For Using Equity Method
PurchaseOfInvestmentsOtherThanInvestmentsAccountedForUsingEquityMethod
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CY2022 ifrs-full Other Cash Payments To Acquire Equity Or Debt Instruments Of Other Entities Classified As Investing Activities
OtherCashPaymentsToAcquireEquityOrDebtInstrumentsOfOtherEntitiesClassifiedAsInvestingActivities
5000000 usd
CY2021 ifrs-full Other Cash Payments To Acquire Equity Or Debt Instruments Of Other Entities Classified As Investing Activities
OtherCashPaymentsToAcquireEquityOrDebtInstrumentsOfOtherEntitiesClassifiedAsInvestingActivities
500000 usd
CY2020 ifrs-full Other Cash Payments To Acquire Equity Or Debt Instruments Of Other Entities Classified As Investing Activities
OtherCashPaymentsToAcquireEquityOrDebtInstrumentsOfOtherEntitiesClassifiedAsInvestingActivities
1150000 usd
CY2022 ifrs-full Other Cash Receipts From Sales Of Equity Or Debt Instruments Of Other Entities Classified As Investing Activities
OtherCashReceiptsFromSalesOfEquityOrDebtInstrumentsOfOtherEntitiesClassifiedAsInvestingActivities
118710000 usd
CY2021 ifrs-full Other Cash Receipts From Sales Of Equity Or Debt Instruments Of Other Entities Classified As Investing Activities
OtherCashReceiptsFromSalesOfEquityOrDebtInstrumentsOfOtherEntitiesClassifiedAsInvestingActivities
218125000 usd
CY2020 ifrs-full Other Cash Receipts From Sales Of Equity Or Debt Instruments Of Other Entities Classified As Investing Activities
OtherCashReceiptsFromSalesOfEquityOrDebtInstrumentsOfOtherEntitiesClassifiedAsInvestingActivities
350586000 usd
CY2022 ptv Payment To Acquire Short Term Notes Receivable From Associate
PaymentToAcquireShortTermNotesReceivableFromAssociate
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CY2021 ptv Payment To Acquire Short Term Notes Receivable From Associate
PaymentToAcquireShortTermNotesReceivableFromAssociate
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CY2020 ptv Payment To Acquire Short Term Notes Receivable From Associate
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CY2022 ptv Cash Receipts From Repayment Of Current Receivables Due From Associates Classified As Investing Activities
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CY2021 ptv Cash Receipts From Repayment Of Current Receivables Due From Associates Classified As Investing Activities
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CY2020 ptv Cash Receipts From Repayment Of Current Receivables Due From Associates Classified As Investing Activities
CashReceiptsFromRepaymentOfCurrentReceivablesDueFromAssociatesClassifiedAsInvestingActivities
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CY2022 ptv Purchases Of Convertible Note
PurchasesOfConvertibleNote
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CY2021 ptv Purchases Of Convertible Note
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CY2020 ptv Purchases Of Convertible Note
PurchasesOfConvertibleNote
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CY2022 ptv Cash In Deconsolidated Subsidiary
CashInDeconsolidatedSubsidiary
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CY2021 ptv Cash In Deconsolidated Subsidiary
CashInDeconsolidatedSubsidiary
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CY2020 ptv Cash In Deconsolidated Subsidiary
CashInDeconsolidatedSubsidiary
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CY2022 ifrs-full Purchase Of Financial Instruments Classified As Investing Activities
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CY2021 ifrs-full Purchase Of Financial Instruments Classified As Investing Activities
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CY2020 ifrs-full Purchase Of Financial Instruments Classified As Investing Activities
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CY2022 ifrs-full Proceeds From Sales Or Maturity Of Financial Instruments Classified As Investing Activities
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CY2021 ifrs-full Proceeds From Sales Or Maturity Of Financial Instruments Classified As Investing Activities
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CY2020 ifrs-full Proceeds From Sales Or Maturity Of Financial Instruments Classified As Investing Activities
ProceedsFromSalesOrMaturityOfFinancialInstrumentsClassifiedAsInvestingActivities
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CY2022 ptv Receipt Of Payment Of Sublease
ReceiptOfPaymentOfSublease
415000 usd
CY2021 ptv Receipt Of Payment Of Sublease
ReceiptOfPaymentOfSublease
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CY2020 ptv Receipt Of Payment Of Sublease
ReceiptOfPaymentOfSublease
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CY2022 ifrs-full Cash Flows From Used In Investing Activities
CashFlowsFromUsedInInvestingActivities
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CY2021 ifrs-full Cash Flows From Used In Investing Activities
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CY2020 ifrs-full Cash Flows From Used In Investing Activities
CashFlowsFromUsedInInvestingActivities
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CY2022 ifrs-full Proceeds From Current Borrowings
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CY2021 ifrs-full Proceeds From Current Borrowings
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CY2020 ifrs-full Proceeds From Current Borrowings
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CY2022 ifrs-full Proceeds From Noncurrent Borrowings
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CY2021 ifrs-full Proceeds From Noncurrent Borrowings
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CY2020 ifrs-full Proceeds From Noncurrent Borrowings
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CY2022 ifrs-full Proceeds From Issue Of Preference Shares
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CY2021 ifrs-full Proceeds From Issue Of Preference Shares
ProceedsFromIssueOfPreferenceShares
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CY2020 ifrs-full Proceeds From Issue Of Preference Shares
ProceedsFromIssueOfPreferenceShares
13750000 usd
CY2022 ifrs-full Proceeds From Issue Of Bonds Notes And Debentures
ProceedsFromIssueOfBondsNotesAndDebentures
393000 usd
CY2021 ifrs-full Proceeds From Issue Of Bonds Notes And Debentures
ProceedsFromIssueOfBondsNotesAndDebentures
2215000 usd
CY2020 ifrs-full Proceeds From Issue Of Bonds Notes And Debentures
ProceedsFromIssueOfBondsNotesAndDebentures
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CY2022 ifrs-full Payments Of Lease Liabilities Classified As Financing Activities
PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities
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CY2021 ifrs-full Payments Of Lease Liabilities Classified As Financing Activities
PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities
3375000 usd
CY2020 ifrs-full Payments Of Lease Liabilities Classified As Financing Activities
PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities
2908000 usd
CY2022 ifrs-full Proceeds From Exercise Of Options
ProceedsFromExerciseOfOptions
332000 usd
CY2021 ifrs-full Proceeds From Exercise Of Options
ProceedsFromExerciseOfOptions
352000 usd
CY2020 ifrs-full Proceeds From Exercise Of Options
ProceedsFromExerciseOfOptions
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CY2022 ptv Settlement Of Rs Us
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CY2021 ptv Settlement Of Rs Us
SettlementOfRSUs
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CY2020 ptv Settlement Of Rs Us
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CY2022 ptv Vesting Of Restricted Stock Units
VestingOfRestrictedStockUnits
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CY2021 ptv Vesting Of Restricted Stock Units
VestingOfRestrictedStockUnits
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CY2020 ptv Vesting Of Restricted Stock Units
VestingOfRestrictedStockUnits
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CY2022 ifrs-full Disclosure Of Summary Of Significant Accounting Policies Explanatory
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Accounting policies<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Description of Business</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Health plc (“PureTech,” the “Parent” or the “Company”) is a public company incorporated, domiciled and registered in the United Kingdom (“UK”). The registered number is 09582467 and the registered address is 8th Floor, 20 Farringdon Street, London EC4A 4AB, United Kingdom.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech’s group financial statements consolidate those of the Company and its subsidiaries (together referred to as the “Group”). The Parent company financial statements present financial information about the Company as a separate entity and not about its Group.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The accounting policies set out below have, unless otherwise stated, been applied consistently to all periods presented in these group financial statements.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basis of Presentation</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The consolidated financial statements of the Group are presented as of December 31, 2022 and 2021, and for the years ended December 31, 2022, 2021 and 2020. The Group financial statements have been approved by the Directors on April 27, 2023, and are prepared in accordance with UK-adopted International Financial Reporting Standards (IFRSs). The Consolidated Financial Statements also comply fully with IFRSs as issued by the International Accounting Standards Board (IASB). UK-adopted IFRSs differs in certain respects from IFRS as issued by the IASB. However, the differences have no impact for the periods presented.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For presentation of the Consolidated Statements of Comprehensive Income/(Loss), the Company uses a classification based on the function of expenses, rather than based on their nature, as it is more representative of the format used for internal reporting and management purposes and is consistent with international practice.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain amounts in the Consolidated Financial Statements and accompanying notes may not add due to rounding. All percentages have been calculated using unrounded amounts.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basis of Measurement </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The consolidated financial statements are prepared on the historical cost basis except that the following assets and liabilities are stated at their fair value: investments held at fair value, short-term and convertible note from associate and liabilities classified as fair value through the profit or loss. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Use of Judgments and Estimates </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In preparing these consolidated financial statements, management has made judgements, estimates and assumptions that affect the application of the Group’s accounting policies and the reported amounts of assets, liabilities, income and expenses. Actual results may differ from these estimates. Estimates and underlying assumptions are reviewed on an on-going basis.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Significant estimation is applied in determining the following:</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Financial instruments valuations (Note 16): when estimating the fair value of subsidiary preferred shares, subsidiary warrants, and subsidiary convertible notes carried at fair value through profit and loss (FVTPL) as well as investments held at fair value, at initial recognition and upon subsequent measurement. Valuation of the aforementioned financial instruments (assets and liabilities) includes making significant estimates, specifically determining the appropriate valuation methodology and making certain estimates such as the future expected returns on the financial instrument in different scenarios, earnings potential of the subsidiary businesses, appropriate discount rate, appropriate volatility, appropriate term to exit and other industry and company specific risk factors.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Significant judgement is also applied in determining the following:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Subsidiary preferred shares liability classification (Note 15): when determining the classification of financial instruments in terms of liability or equity. These judgements include an assessment of whether the financial instruments include any embedded derivative features, whether they include contractual obligations of the Group to deliver cash or other financial assets or to exchange financial assets or financial liabilities with another party, and whether that obligation will be settled by the Company exchanging a fixed amount of cash or other financial assets for a fixed number of its own equity instruments. Further information about these critical judgements and estimates is included below under Financial Instruments.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">When the power to control the subsidiaries exists (please refer to Notes 5 and 6 and accounting policy below Subsidiaries). This judgement includes an assessment of whether the Company has (i) power over the investee; (ii) exposure, or rights, to variable returns from its involvement with the investee; and (iii) the ability to use its power over the investee to affect the amount of the investor’s returns. The Company considers among others its voting shares, shareholder agreements, ability to appoint board members, representation on the board, rights to appoint management, de facto control, investee dependence on the Company etc. If the power to control investees exists we consolidate the financial statements of such investee in the consolidated financial statements of the Group. Upon issuance of new shares in a subsidiary and/or a change in any shareholders or governance agreements, the Group reassesses its ability to control the investee based on the revised voting interest and board composition and revised subsidiary governance and management structure. When such new circumstances result in the Group losing its power to control the investee, the investee is deconsolidated.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Whether the Company has significant influence over financial and operating policies of investees in order to determine if the Company should account for its investment as an associate based on IAS 28 or based on IFRS 9, Financial Instruments (please refer to Note 5). This judgement includes, among others, an assessment whether the Company has representation on the Board of Directors of the investee, whether the Company participates in the policy making processes of the investee, whether there is any interchange of managerial personnel, whether there is any essential technical information provided to the investee and if there are any transactions between the Company and the investee.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Upon determining that the Company does have significant influence over the financial and operating policies of an investee, if the Company holds more than a single instrument issued by its equity-accounted investee, judgement is required to determine whether the additional instrument forms part of the investment in the associate, which is accounted for under IAS 28 and scoped out of IFRS 9, or it is a separate financial instrument that falls in the scope of IFRS 9 (please refer to Notes 5 and 6). This judgement includes an assessment of the characteristics of the financial instrument of the investee held by the Company and whether such financial instrument provides access to returns underlying an ownership interest.</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Where the company has other investments in an equity accounted investee that are not accounted for under IAS 28, judgement is required in determining if such investments constitute Long-Term Interests for the purposes of IAS 28 (please refer to Notes 5 and 6). This determination is based on the individual facts and circumstances and characteristics of each investment, but is driven, among other factors, by the intention and likelihood to settle the instrument through redemption or repayment in the foreseeable future, and whether or not the investment is likely to be converted to common stock or other equity instruments (please also refer to accounting policy with regard to Investments in Associates below). When the Group considered the individual facts and circumstances of the Group’s investment in its associate's preferred stock in the manner described above, including the long-term nature of such investment, the ability of the Group to convert its preferred stock investment to an investment in common shares and the likelihood of such conversion, we concluded that such investment was considered a Long Term Interest.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2022, the Group had cash and cash equivalents of $149.9 million and short-term investments of $200.2 million. Considering the Group’s and the Company's financial position as of December 31, 2022, and its principal risks and opportunities, a going concern analysis has been prepared for at least the twelve-month period from the date of signing the Consolidated Financial Statements ("the going concern period") utilizing realistic scenarios and applying a severe but plausible downside scenario. Even under the downside scenario, the analysis demonstrates the Group and the Company continue to maintain sufficient liquidity headroom and continue to comply with all financial obligations. The Directors believe the Group and the Company is adequately resourced to continue in operational existence for at least the twelve-month period from the date of signing the Consolidated Financial Statements. Accordingly, the Directors considered it appropriate to adopt the going concern basis of accounting in preparing the Consolidated Financial Statements and the PureTech Health plc Financial Statements. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basis of consolidation</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The consolidated financial information as of December 31, 2022 and 2021, and for each of the years ended December 31, 2022, 2021 and 2020, comprises an aggregation of financial information of the Company and the consolidated financial information of PureTech Health LLC (“PureTech LLC”). Intra-group balances and transactions, and any unrealized income and expenses arising from intra-group transactions, are eliminated.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiaries </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As used in these financial statements, the term subsidiaries refers to entities that are controlled by the Group. Financial results of subsidiaries of the Group as of December 31, 2022, are reported within the Internal segment, Controlled Founded Entities segment or the Parent Company and Other section (please refer to Note 4). Under applicable accounting rules, the Group controls an entity when it is exposed to, or has the rights to, variable returns from its involvement with the entity and has the ability to affect those returns through its power over the entity. In assessing control, the Group takes into consideration potential voting rights, board representation, shareholders' agreements, ability to appoint Directors and management, de facto control and other related factors. The financial statements of subsidiaries are included in the consolidated financial statements from the date that control commences until the date that control ceases. Losses applicable to the non-controlling interests in a subsidiary are allocated to the non-controlling interests even if doing so causes the non-controlling interests to have a deficit balance.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">A list of all current and former subsidiaries organized with respect to classification as of December 31, 2022, and the Group’s total voting percentage, based on outstanding voting common and preferred shares as of December 31, 2022, 2021 and 2020, is outlined below. All current subsidiaries are domiciled within the United States and conduct business activities solely within the United States. </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:41.489%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.260%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.424%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.260%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.424%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.263%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="24" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Voting percentage at December 31, through the holdings in</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Common</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%"> Preferred</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Common</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%"> Preferred</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Common</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%"> Preferred</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Subsidiary operating companies</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio Therapeutics, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">91.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega, Inc. (indirectly held through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">77.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">77.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">83.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica, Incorporated</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">56.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">56.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">56.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT (formerly Ariya Therapeutics, Inc.) </span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT-100</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Management, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Health LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">59.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences Securities Corp. (indirectly held through Vedanta)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">59.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Deconsolidated former subsidiary operating companies</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde Health, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2,5</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">40.2</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Akili Interactive Labs, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">6</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">26.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2,6</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">22.8</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20.2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna Therapeutics, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3.1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vor Biopharma Inc.1,2 </span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16.4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Nontrading holding companies</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.4pt;font-weight:400;line-height:120%">Endra Holdings, LLC (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.46pt;font-weight:400;line-height:120%;position:relative;top:-2.94pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.4pt;font-weight:400;line-height:120%">Ensof Holdings, LLC (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.46pt;font-weight:400;line-height:120%;position:relative;top:-2.94pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Securities Corp.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Securities II Corp.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Inactive subsidiaries</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Appeering, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Commense Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99.1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Enlight Biosciences, LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8pt;font-weight:400;line-height:120%">Ensof Biosystems, Inc. (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.2pt;font-weight:400;line-height:120%;position:relative;top:-2.8pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">57.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Knode Inc. (indirectly held through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Libra Biosciences, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Mandara Sciences, LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">98.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">98.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">98.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tal Medical, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    The voting percentage is impacted by preferred shares that are classified as liabilities, which results in the ownership percentage not being the same as the ownership percentage used in allocations to non-controlling interests disclosed in Note 18. The allocation of losses/profits to the noncontrolling interest is based on the holdings of subordinated stock that provide ownership rights in the subsidiaries. The ownership of liability classified preferred shares are quantified in Note 15.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Registered address is Corporation Trust Center, 1209 Orange St., Wilmington, DE 19801, USA.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Registered address is 2711 Centerville Rd., Suite 400, Wilmington, DE 19808, USA.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">4    The Company’s interests in its subsidiaries are predominantly in the form of preferred shares, which have a liquidation preference over the common stock, are convertible into common stock at the holder’s discretion or upon certain liquidity events, are entitled to one vote per share on all matters submitted to shareholders for a vote and entitled to receive dividends when and if declared. In the case of Enlight, Mandara and PureTech Health LLC, the holdings are membership interests in an LLC. The holders of common stock are entitled to one vote per share on all matters submitted to shareholders for a vote and entitled to receive dividends when and if declared.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">5    On May 25, 2022 PureTech lost control over Sonde and Sonde was deconsolidated from the Group’s financial statements, resulting in only the profits and losses generated by Sonde through the deconsolidation date being included in the Group’s Consolidated Statement of Comprehensive Income/(Loss). See Notes 5 and 6 for further details about the accounting for the investments in Sonde subsequent to deconsolidation.</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">6    See Notes 5 and 6 for the Gelesis and Akili SPAC merger and for the exchange of the Group's preferred stock investments for common stock of those entities.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span><br/></span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in subsidiary ownership and loss of control </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in the Group’s interest in a subsidiary that do not result in a loss of control are accounted for as equity transactions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Where the Group loses control of a subsidiary, the assets and liabilities are derecognized along with any related non-controlling interest (“NCI”). Any interest retained in the former subsidiary is measured at fair value when control is lost. Any resulting gain or loss is recognized as profit or loss in the Consolidated Statements of Comprehensive Income/(Loss).</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Associates </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As used in these financial statements, the term associates are those entities in which the Group has no control but maintains significant influence over the financial and operating policies. Significant influence is presumed to exist when the Group holds between 20 and 50 percent of the voting power of an entity, unless it can be clearly demonstrated that this is not the case. The Group evaluates if it maintains significant influence over associates by assessing if the Group has lost the power to participate in the financial and operating policy decisions of the associate.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Application of the equity method to associates </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Associates are accounted for using the equity method (equity accounted investees) and are initially recognized at cost, or if recognized upon deconsolidation they are initially recorded at fair value at the date of deconsolidation. The consolidated financial statements include the Group’s share of the total comprehensive income and equity movements of equity accounted investees, from the date that significant influence commences until the date that significant influence ceases. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">To the extent the Group holds interests in associates that are not providing access to returns underlying ownership interests, the instrument held by PureTech is accounted for in accordance with IFRS 9 as investments held at fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">When the Group’s share of losses exceeds its equity method investment in the investee, losses are applied against Long-Term Interests, which are investments accounted for under IFRS 9. Investments are determined to be Long-Term Interests when they are long-term in nature and in substance they form part of the Group's net investment in that associate. This determination is impacted by many factors, among others, whether settlement by the investee through redemption or repayment is planned or likely in the foreseeable future, whether the investment can be converted and/or is likely to be converted to common stock or other equity instrument and other factors regarding the nature of the investment. Whilst this assessment is dependent on many specific facts and circumstances of each investment, typically conversion features whereby the investment is likely to convert to common stock or other equity instruments would point to the investment being a Long-Term Interest. Similarly, where the investment is not planned or likely to be settled through redemption or repayment in the foreseeable future, this would indicate that the investment is a Long-Term Interest. When the net investment in the associate, which includes the Group’s investments in other long-term interests, is reduced to nil, recognition of further losses is discontinued except to the extent that the Group has incurred legal or constructive obligations or made payments on behalf of an investee.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has also adopted the amendments to IAS 28 Investments in Associates that addresses the dual application of IAS 28 and IFRS 9 (see below) when equity method losses are applied against Long-Term Interests (LTI). The amendments provide the annual sequence in which both standards are to be applied in such a case. The Group has applied the equity method losses to the LTIs presented as part of Investments held at fair value subsequent to remeasuring such investments to their fair value at balance sheet date.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Instruments </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Classification </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group classifies its financial assets in the following measurement categories:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Those to be measured subsequently at fair value (either through other comprehensive income, or through profit or loss), and</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Those to be measured at amortized cost.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The classification depends on the Group’s business model for managing the financial assets and the contractual terms of the cash flows.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For assets measured at fair value, gains and losses are recorded in profit or loss. For investments in equity instruments that are not held for trading, this will depend on whether the Group has made an irrevocable election at the time of initial recognition to account for the equity investment at FVOCI. As of balance sheet dates, none of the Company's financial assets are accounted for as FVOCI.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Measurement </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">At initial recognition, the Group measures a financial asset at its fair value plus, in the case of a financial asset not at FVTPL, transaction costs that are directly attributable to the acquisition of the financial asset. Transaction costs of financial assets that are carried at FVTPL are expensed.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group assesses on a forward-looking basis the expected credit losses associated with its debt instruments carried at amortized cost. For trade receivables, the Group applies the simplified approach permitted by IFRS 9, which requires expected lifetime losses to be recognized from initial recognition of the receivables.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s financial assets consist of cash and cash equivalents, investments in debt securities, trade and other receivables, notes, restricted cash deposits and investments in equity securities. The Group’s financial assets are virtually all classified into the following categories: investments held at fair value, notes, trade and other receivables, short-term investments and cash and cash equivalents. The Group determines the classification of financial assets at initial recognition depending on the purpose for which the financial assets were acquired.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value are investments in equity instruments that are not held for trading. Such investments consist of the Group's minority interest holdings where the Group has no significant influence or preferred share investments in the Group's associates that are not providing access to returns underlying ownership interests. These financial assets are initially measured at fair value and subsequently re-measured at fair value at each reporting date. The Company elects if the gain or loss will be recognized in Other Comprehensive Income/(Loss) or through profit and loss on an instrument by instrument basis. The Company has elected to record the changes in fair values for the financial assets falling under this category through profit and loss. Please refer to Note 5.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in the fair value of financial assets at FVTPL are recognized in other income/(expense) in the Consolidated Statements of Comprehensive Income/(Loss) as applicable. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The notes from an associate, since their contractual terms do not consist solely of cash flow payments of principal and interest on the principal amount outstanding, such notes are initially and subsequently measured at fair value, with changes in fair value recognized through profit and loss.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short term investments consist of short-term US treasury bills that are held to maturity. The contractual terms consist solely of payment of the principal and the Group's business model is to hold the treasury bills to maturity. As such, such short term </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">investments are recorded at amortized cost. As of balance sheet date amortized cost approximated the fair value of such short-term investments.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables are non-derivative financial assets with fixed and determinable payments that are not quoted on active markets. These financial assets are carried at the amounts expected to be received less any expected lifetime losses. Such losses are determined taking into account previous experience, credit rating and economic stability of counterparty and economic conditions. When a trade receivable is determined to be uncollectible, it is written off against the available provision. As of balance sheet date, The Group did not incur or record any such expected lifetime losses. Trade and other receivables are included in current assets, unless maturities are greater than 12 months after the end of the reporting period.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Liabilities </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s financial liabilities consist of trade and other payables, subsidiary notes payable, long-term loan, preferred shares, and warrant liability. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrant liabilities are initially recognized at fair value. After initial recognition, these financial liabilities are re-measured at FVTPL using an appropriate valuation technique. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable without embedded derivatives and the long-term loan are accounted for at amortized cost.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The majority of the Group’s subsidiaries have preferred shares and certain notes payable with embedded derivatives, which are classified as current liabilities. When the Group has preferred shares and notes with embedded derivatives that qualify for bifurcation, the Group has elected to account for the entire instrument as FVTPL after determining under IFRS 9 that the instrument qualifies to be accounted for under such FVTPL method.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group derecognizes a financial liability when its contractual obligations are discharged, cancelled or expire.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity Instruments Issued by the Group </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial instruments issued by the Group are treated as equity only to the extent that they meet the following two conditions, in accordance with IAS 32:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:4.26pt">They include no contractual obligations upon the Group to deliver cash or other financial assets or to exchange financial assets or financial liabilities with another party under conditions that are potentially unfavorable to the Group; and</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:4.26pt">Where the instrument will or may be settled in the Group’s own equity instruments, it is either a non-derivative that includes no obligation to deliver a variable number of the Group’s own equity instruments or is a derivative that will be settled by the Group exchanging a fixed amount of cash or other financial assets for a fixed number of its own equity instruments.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">To the extent that this definition is not met, the financial instrument is classified as a financial liability. Where the instrument so classified takes the legal form of the Group’s own shares, the amounts presented in the Group's shareholders' equity exclude amounts in relation to those shares.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in the fair value of liabilities at FVTPL are recognized in Net finance income (costs) in the Consolidated Statements of Comprehensive Income/(Loss) as applicable. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">IFRS 15, Revenue from Contracts with Customers </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The standard establishes a five-step principle-based approach for revenue recognition and is based on the concept of recognizing an amount that reflects the consideration for performance obligations only when they are satisfied and the control of goods or services is transferred.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The majority of the Group’s contract revenue is generated from licenses and services, some of which are part of collaboration arrangements. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Management reviewed contracts where the Group received consideration in order to determine whether or not they should be accounted for in accordance with IFRS 15. To date, PureTech has entered into transactions that generate revenue and meet the scope of either IFRS 15 or IAS 20 Accounting for Government Grants. Contract revenue is recognized at either a point-in-time or over time, depending on the nature of the performance obligations.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group accounts for agreements that meet the definition of IFRS 15 by applying the following five step model:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Identify the contract(s) with a customer – A contract with a customer exists when (i) the Group enters into an enforceable contract with a customer that defines each party’s rights regarding the goods or services to be transferred and identifies the payment terms related to those goods or services, (ii) the contract has commercial substance and, (iii) the Group determines that collection of substantially all consideration for goods or services that are transferred is probable based on the customer’s intent and ability to pay the promised consideration.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Identify the performance obligations in the contract – Performance obligations promised in a contract are identified based on the goods or services that will be transferred to the customer that are both capable of being distinct, whereby the customer can benefit from the good or service either on its own or together with other resources that are readily available from third parties or from the Group, and are distinct in the context of the contract, whereby the transfer of the goods or services is separately identifiable from other promises in the contract.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Determine the transaction price – The transaction price is determined based on the consideration to which the Group will be entitled in exchange for transferring goods or services to the customer. To the extent the transaction price includes variable consideration, the Group estimates the amount of variable consideration that should be included in the transaction price utilizing either the expected value method or the most likely amount method depending on the nature of the variable consideration. Variable consideration is included in the transaction price if, in the Group’s judgement, it is probable that a significant future reversal of cumulative revenue under the contract will not occur. </span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Allocate the transaction price to the performance obligations in the contract – If the contract contains a single performance obligation, the entire transaction price is allocated to the single performance obligation. Contracts that contain multiple performance obligations require an allocation of the transaction price to each performance obligation based on a relative standalone selling price basis. </span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Recognize revenue when (or as) the Group satisfies a performance obligation – The Group satisfies performance obligations either over time or at a point in time as discussed in further detail below. Revenue is recognized at the time the related performance obligation is satisfied by transferring a promised good or service to a customer.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue generated from services agreements (typically where licenses and related services were combined into one performance obligation) is determined to be recognized over time when it can be determined that the services meet one of the following: (a) the customer simultaneously receives and consumes the benefits provided by the entity’s performance as the entity performs; (b) the entity’s performance creates or enhances an asset that the customer controls as the asset is created or enhanced; or (c) the entity’s performance does not create an asset with an alternative use to the entity and the entity has an enforceable right to payment for performance completed to date.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">It was determined that the Group has contracts that meet criteria (a), since the customer simultaneously receives and consumes the benefits provided by the Company’s performance as the Company performs. Therefore revenue is recognized over time using the input method based on costs incurred to date as compared to total contract costs. The Company believes that in research and development service type agreements using costs incurred to date represents the most faithful depiction of the entity’s performance towards complete satisfaction of a performance obligation.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue from licenses that are not part of a combined performance obligation are recognized at a point in time due to the licenses relating to intellectual property that has significant stand-alone functionality and as such represent a right to use the entity's intellectual property as it exists at the point in time at which the license is granted.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Royalty income received in respect of licensing agreements is recognized as the related third party sales in the licensee occur.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amounts that are receivable or have been received per contractual terms but have not been recognized as revenue since performance has not yet occurred or has not yet been completed are recorded as deferred revenue. The Company classifies as non-current deferred revenue amounts received for which performance is expected to occur beyond one year or one operating cycle.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant Income </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company recognizes grants from governmental agencies as grant income in the Consolidated Statement of Comprehensive Income/(Loss), gross of the expenditures that were related to obtaining the grant, when there is reasonable assurance that the Company will comply with the conditions within the grant agreement and there is reasonable assurance that payments under the grants will be received. The Company evaluates the conditions of each grant as of each reporting date to ensure that the Company has reasonable assurance of meeting the conditions of each grant arrangement and that it is expected that the grant payment will be received as a result of meeting the necessary conditions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company submits qualifying expenses for reimbursement after the Company has incurred the research and development expense. The Company records an unbilled receivable upon incurring such expenses. In cases were grant income is received prior to the expenses being incurred or recognized, the amounts received are deferred until the related expense is incurred and/or recognized. Grant income is recognized in the Consolidated Statements of Comprehensive Income/(Loss) at the time in which the Company recognizes the related reimbursable expense for which the grant is intended to compensate.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Functional and Presentation Currency </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">These consolidated financial statements are presented in United States dollars (“US dollars”). The functional currency of all members of the Group is the U.S. dollar. The Group's share in foreign exchange differences in associates were reported in Other Comprehensive Income/(Loss).</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Foreign Currency </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transactions in foreign currencies are translated to the respective functional currencies of Group entities at the foreign exchange rate ruling at the date of the transaction. Monetary assets and liabilities denominated in foreign currencies at the balance sheet date are retranslated to the functional currency at the foreign exchange rate ruling at that date. Foreign exchange differences arising on remeasurement are recognized in the Consolidated Statement of Comprehensive Income/(Loss). Non-monetary assets and liabilities that are measured in terms of historical cost in a foreign currency are translated using the exchange rate at the date of the transaction. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and Cash Equivalents </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and cash equivalents include all highly liquid instruments with original maturities of three months or less.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share Capital </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Ordinary shares are classified as equity. The Group's equity is comprised of share capital, share premium, merger reserve, other reserve, translation reserve, and retained earnings/accumulated deficit.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Treasury Shares</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Treasury shares are recognized at cost and are deducted from shareholders' equity. No gain or loss is recognized in profit and loss for the purchase, sale, re-issue or cancellation of the Company's own equity shares</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Property and Equipment </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Property and equipment is stated at cost less accumulated depreciation and any accumulated impairment losses. Cost includes expenditures that are directly attributable to the acquisition of the asset. Assets under construction represent leasehold improvements and machinery and equipment to be used in operations or research and development activities. When parts of an item of property and equipment have different useful lives, they are accounted for as separate items (major components) of property and equipment. Depreciation is calculated using the straight-line method over the estimated useful life of the related asset: </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:48.821%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:48.979%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Laboratory and manufacturing equipment</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2-8 years</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Furniture and fixtures</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7 years</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Computer equipment and software</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1-5 years</span></div></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Leasehold improvements</span></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5-10 years, or the remaining term of the lease, if shorter</span></div></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation methods, useful lives and residual values are reviewed at each balance sheet date.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Intangible Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Intangible assets, which include purchased patents and licenses with finite useful lives, are carried at historical cost less accumulated amortization, if amortization has commenced. Intangible assets with finite lives are amortized from the time they are available for their intended use. Amortization is calculated using the straight-line method to allocate the costs of patents and licenses over their estimated useful lives. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development intangible assets, which are still under development and have accordingly not yet obtained marketing approval, are presented as In-Process Research and Development (IPR&amp;D). IPR&amp;D is not amortized since it is not yet available for its intended use, but it is evaluated for potential impairment on an annual basis or more frequently when facts and circumstances warrant.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Impairment of Non-Financial Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group reviews the carrying amounts of its property and equipment and intangible assets at each reporting date to determine whether there are indicators of impairment. If any such indicators of impairment exist, then an asset’s recoverable amount is estimated. The recoverable amount is the higher of an asset’s fair value less cost of disposal and value in use.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company’s IPR&amp;D intangible assets are not yet available for their intended use. As such, they are tested for impairment at least annually. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">An impairment loss is recognized when an asset’s carrying amount exceeds its recoverable amount. For the purposes of impairment testing, assets are grouped at the lowest levels for which there are largely independent cash flows. If a non- financial asset instrument is impaired, an impairment loss is recognized in the Consolidated Statements of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments in associates are considered impaired if, and only if, objective evidence indicates that one or more events, which occurred after the initial recognition, have had an impact on the future cash flows from the net investment and that impact can be reliably estimated. If an impairment exists the Company measures an impairment by comparing the carrying value of the net investment in the associate to its recoverable amount and recording any excess as an impairment loss. See Note 6 for impairment recorded in respect of an investment in associate during the year ended December 31, 2022.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Employee Benefits </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Short-Term Employee Benefits </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term employee benefit obligations are measured on an undiscounted basis and expensed as the related service is provided. A liability is recognized for the amount expected to be paid if the Group has a present legal or constructive obligation due to past service provided by the employee, and the obligation can be estimated reliably.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Defined Contribution Plans </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">A defined contribution plan is a post-employment benefit plan under which an entity pays fixed contributions into a separate entity and has no legal or constructive obligation to pay further amounts. Obligations for contributions to defined contribution plans are recognized as an employee benefit expense in the periods during which related services are rendered by employees. Prepaid contributions are recognized as an asset to the extent that a cash refund or a reduction in future payments is available. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Share-based Payments </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment arrangements, in which the Group receives goods or services as consideration for its own equity instruments, are accounted for as equity-settled share-based payment transactions (except certain restricted stock units - see below) in accordance with IFRS 2, regardless of how the equity instruments are obtained by the Group. The grant date fair value of employee share-based payment awards is recognized as an expense with a corresponding increase in equity over the requisite service period related to the awards. The amount recognized as an expense is adjusted to reflect the actual number of awards for which the related service and non-market performance conditions are expected to be met, such that the amount ultimately recognized as an expense is based on the number of awards that do meet the related service and non-market performance conditions at the vesting date. For share-based payment awards with market conditions, the grant date fair value is measured to reflect such conditions and there is no true-up for differences between expected and actual outcomes.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain restricted stock units are treated as liability settled awards starting in 2021. Such awards are remeasured at every reporting date until settlement date and are recognized as compensation expense over the requisite service period. Differences in remeasurement are recognized in profit and loss. The cumulative cost that will ultimately be recognized in respect of these awards will equal to the amount at settlement. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the awards is measured using option pricing models and other appropriate models, which take into account the terms and conditions of the awards granted. See further details in Note 8.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Development Costs </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expenditures on research activities are recognized as incurred in the Consolidated Statements of Comprehensive Income/(Loss). In accordance with IAS 38 development costs are capitalized only if the expenditure can be measured reliably, the product or process is technically and commercially feasible, future economic benefits are probable, the Group can demonstrate its ability to use or sell the intangible asset, the Group intends to and has sufficient resources to complete development and to use or sell the asset, and it is able to measure reliably the expenditure attributable to the intangible asset during its development. The point at which technical feasibility is determined to have been reached is, generally, when regulatory approval has been received where applicable. Management determines that commercial viability has been reached </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">when a clear market and pricing point have been identified, which may coincide with achieving meaningful recurring sales. Otherwise, the development expenditure is recognized as incurred in the Consolidated Statements of Comprehensive Income/(Loss). As of balance sheet date the Group has not capitalized any development costs.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Provisions </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">A provision is recognized in the Consolidated Statements of Financial Position when the Group has a present legal or constructive obligation due to a past event that can be reliably measured, and it is probable that an outflow of economic benefits will be required to settle the obligation. Provisions are determined by discounting the expected future cash flows at a pre-tax rate that reflects risks specific to the liability.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Leases</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group leases real estate (and some minor equipment) for use in operations. These leases generally have lease terms of 1 to 10 years. The Group includes options that are reasonably certain to be exercised as part of the determination of the lease term. The group determines if an arrangement is a lease at inception of the contract in accordance with guidance detailed in IFRS 16. ROU assets represent the Group’s right to use an underlying asset for the lease term and lease liabilities represent the Group's obligation to make lease payments arising from the lease. Operating lease ROU assets and lease liabilities are recognized at commencement date based on the present value of the lease payments over the lease term. As most of the Group's leases do not provide an implicit rate, The Group used its estimated incremental borrowing rate, based on information available at commencement date, in determining the present value of future payments. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s leases are virtually all leases of real estate.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has elected to account for lease payments as an expense on a straight-line basis over the life of the lease for: </span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Leases with a term of 12 months or less and containing no purchase options; and </span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Leases where the underlying asset has a value of less than $5,000. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The right-of-use asset is depreciated on a straight-line basis and the lease liability gives rise to an interest charge. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Further information regarding the subleases, right of use asset and lease liability can be found in Note 21.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance Income and Finance Costs </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income is comprised of income on funds invested in U.S. treasuries, income on money market funds and income on a finance lease. Financing income is recognized as it is earned. Finance costs comprise mainly of loan, notes and lease liability interest expenses and the changes in the fair value of financial liabilities carried at FVTPL (such changes can consist of finance income when the fair value of such financial liabilities decreases).</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax on the profit or loss for the year comprises current and deferred income tax. In accordance with IAS 12, tax is recognized in the Consolidated Statements of Comprehensive Income/(Loss) except to the extent that it relates to items recognized directly in equity.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current income tax is the expected tax payable or receivable on the taxable income or loss for the year, using tax rates enacted or substantially enacted at the reporting date, and any adjustment to tax payable in respect of previous years.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax is recognized due to temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for taxation purposes. Deferred tax assets are recognized for unused tax losses, unused tax credits and deductible temporary differences to the extent that it is probable that future taxable profits will be available against which they can be used. Deferred tax assets with respect to investments in associates are recognized only to the extent that it is probable the temporary difference will reverse in the foreseeable future and taxable profit will be available against which the temporary difference can be utilised. Deferred tax assets are reviewed at each reporting date and are reduced to the extent that it is no longer probable that the related tax benefit will be realized.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax is measured at the tax rates that are expected to be applied to temporary differences when they reverse, using tax rates enacted or substantively enacted at the reporting date.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred income tax assets and liabilities are offset when there is a legally enforceable right to offset current tax assets against current tax liabilities and when the deferred income tax assets and liabilities relate to income taxes levied by the same taxation authority on either the same taxable entity or different taxable entities where there is an intention to settle the balances on a net basis.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair Value Measurements </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s accounting policies require that certain financial assets and certain financial liabilities be measured at their fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group uses valuation techniques that are appropriate in the circumstances and for which sufficient data are available to measure fair value, maximizing the use of relevant observable inputs and minimizing the use of unobservable inputs. Fair values are categorized into different levels in a fair value hierarchy based on the inputs used in the valuation techniques as follows:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 1: quoted prices (unadjusted) in active markets for identical assets or liabilities.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 2: inputs other than quoted prices included in Level 1 that are observable for the asset or liability, either directly (i.e. as prices) or indirectly (i.e. derived from prices).</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 3: inputs for the asset or liability that are not based on observable market data (unobservable inputs).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group recognizes transfers between levels of the fair value hierarchy at the end of the reporting period during which the change has occurred.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The carrying amount of cash and cash equivalents, accounts receivable, restricted cash, deposits, accounts payable, accrued expenses and other current liabilities in the Group’s Consolidated Statements of Financial Position approximates their fair value because of the short maturities of these instruments. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating Segments </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating segments are reported in a manner that is consistent with the internal reporting provided to the chief operating decision maker (“CODM”). The CODM reviews discrete financial information for the operating segments in order to assess their performance and is responsible for making decisions about resources allocated to the segments. The CODM has been identified as the Group’s Directors.</span></div>
CY2022 ifrs-full Explanation Of Measurement Bases Used In Preparing Financial Statements
ExplanationOfMeasurementBasesUsedInPreparingFinancialStatements
Basis of Measurement The consolidated financial statements are prepared on the historical cost basis except that the following assets and liabilities are stated at their fair value: investments held at fair value, short-term and convertible note from associate and liabilities classified as fair value through the profit or loss.
CY2022Q4 ifrs-full Cash And Cash Equivalents
CashAndCashEquivalents
149900000 usd
CY2022Q4 ptv Short Term Investments
ShortTermInvestments
200200000 usd
CY2020 ifrs-full Revenue From Government Grants
RevenueFromGovernmentGrants
3427000 usd
CY2022 ifrs-full Description Of Accounting Policy For Subsidiaries Explanatory
DescriptionOfAccountingPolicyForSubsidiariesExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiaries </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As used in these financial statements, the term subsidiaries refers to entities that are controlled by the Group. Financial results of subsidiaries of the Group as of December 31, 2022, are reported within the Internal segment, Controlled Founded Entities segment or the Parent Company and Other section (please refer to Note 4). Under applicable accounting rules, the Group controls an entity when it is exposed to, or has the rights to, variable returns from its involvement with the entity and has the ability to affect those returns through its power over the entity. In assessing control, the Group takes into consideration potential voting rights, board representation, shareholders' agreements, ability to appoint Directors and management, de facto control and other related factors. The financial statements of subsidiaries are included in the consolidated financial statements from the date that control commences until the date that control ceases. Losses applicable to the non-controlling interests in a subsidiary are allocated to the non-controlling interests even if doing so causes the non-controlling interests to have a deficit balance.</span></div>
CY2022 ifrs-full Disclosure Of Significant Investments In Subsidiaries Explanatory
DisclosureOfSignificantInvestmentsInSubsidiariesExplanatory
All current subsidiaries are domiciled within the United States and conduct business activities solely within the United States. <div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:41.489%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.260%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.424%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.260%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.424%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:8.263%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="24" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Voting percentage at December 31, through the holdings in</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Common</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%"> Preferred</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Common</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%"> Preferred</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Common</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"><span style="font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%"> Preferred</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Subsidiary operating companies</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio Therapeutics, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">91.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega, Inc. (indirectly held through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">77.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">77.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">83.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica, Incorporated</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">56.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">56.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">56.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT (formerly Ariya Therapeutics, Inc.) </span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech LYT-100</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Management, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Health LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">59.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences Securities Corp. (indirectly held through Vedanta)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">59.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Deconsolidated former subsidiary operating companies</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde Health, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2,5</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">40.2</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Akili Interactive Labs, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">6</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">26.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2,6</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">22.8</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.9 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20.2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna Therapeutics, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3.1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">12.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vor Biopharma Inc.1,2 </span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.6 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16.4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Nontrading holding companies</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.4pt;font-weight:400;line-height:120%">Endra Holdings, LLC (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.46pt;font-weight:400;line-height:120%;position:relative;top:-2.94pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:justify"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.4pt;font-weight:400;line-height:120%">Ensof Holdings, LLC (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.46pt;font-weight:400;line-height:120%;position:relative;top:-2.94pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Securities Corp.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PureTech Securities II Corp.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Inactive subsidiaries</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Appeering, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Commense Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99.1</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99.1 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Enlight Biosciences, LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8pt;font-weight:400;line-height:120%">Ensof Biosystems, Inc. (held indirectly through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.2pt;font-weight:400;line-height:120%;position:relative;top:-2.8pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">57.7</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57.7 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">28.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Knode Inc. (indirectly held through Enlight)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">86.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Libra Biosciences, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Mandara Sciences, LLC</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">98.3</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">98.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">98.3 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tal Medical, Inc.</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">100.0</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100.0 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    The voting percentage is impacted by preferred shares that are classified as liabilities, which results in the ownership percentage not being the same as the ownership percentage used in allocations to non-controlling interests disclosed in Note 18. The allocation of losses/profits to the noncontrolling interest is based on the holdings of subordinated stock that provide ownership rights in the subsidiaries. The ownership of liability classified preferred shares are quantified in Note 15.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Registered address is Corporation Trust Center, 1209 Orange St., Wilmington, DE 19801, USA.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Registered address is 2711 Centerville Rd., Suite 400, Wilmington, DE 19808, USA.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">4    The Company’s interests in its subsidiaries are predominantly in the form of preferred shares, which have a liquidation preference over the common stock, are convertible into common stock at the holder’s discretion or upon certain liquidity events, are entitled to one vote per share on all matters submitted to shareholders for a vote and entitled to receive dividends when and if declared. In the case of Enlight, Mandara and PureTech Health LLC, the holdings are membership interests in an LLC. The holders of common stock are entitled to one vote per share on all matters submitted to shareholders for a vote and entitled to receive dividends when and if declared.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">5    On May 25, 2022 PureTech lost control over Sonde and Sonde was deconsolidated from the Group’s financial statements, resulting in only the profits and losses generated by Sonde through the deconsolidation date being included in the Group’s Consolidated Statement of Comprehensive Income/(Loss). See Notes 5 and 6 for further details about the accounting for the investments in Sonde subsequent to deconsolidation.</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">6    See Notes 5 and 6 for the Gelesis and Akili SPAC merger and for the exchange of the Group's preferred stock investments for common stock of those entities.</span></div>
CY2022 ifrs-full Description Of Accounting Policy For Investment In Associates
DescriptionOfAccountingPolicyForInvestmentInAssociates
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Associates </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As used in these financial statements, the term associates are those entities in which the Group has no control but maintains significant influence over the financial and operating policies. Significant influence is presumed to exist when the Group holds between 20 and 50 percent of the voting power of an entity, unless it can be clearly demonstrated that this is not the case. The Group evaluates if it maintains significant influence over associates by assessing if the Group has lost the power to participate in the financial and operating policy decisions of the associate.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Application of the equity method to associates </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Associates are accounted for using the equity method (equity accounted investees) and are initially recognized at cost, or if recognized upon deconsolidation they are initially recorded at fair value at the date of deconsolidation. The consolidated financial statements include the Group’s share of the total comprehensive income and equity movements of equity accounted investees, from the date that significant influence commences until the date that significant influence ceases. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">To the extent the Group holds interests in associates that are not providing access to returns underlying ownership interests, the instrument held by PureTech is accounted for in accordance with IFRS 9 as investments held at fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">When the Group’s share of losses exceeds its equity method investment in the investee, losses are applied against Long-Term Interests, which are investments accounted for under IFRS 9. Investments are determined to be Long-Term Interests when they are long-term in nature and in substance they form part of the Group's net investment in that associate. This determination is impacted by many factors, among others, whether settlement by the investee through redemption or repayment is planned or likely in the foreseeable future, whether the investment can be converted and/or is likely to be converted to common stock or other equity instrument and other factors regarding the nature of the investment. Whilst this assessment is dependent on many specific facts and circumstances of each investment, typically conversion features whereby the investment is likely to convert to common stock or other equity instruments would point to the investment being a Long-Term Interest. Similarly, where the investment is not planned or likely to be settled through redemption or repayment in the foreseeable future, this would indicate that the investment is a Long-Term Interest. When the net investment in the associate, which includes the Group’s investments in other long-term interests, is reduced to nil, recognition of further losses is discontinued except to the extent that the Group has incurred legal or constructive obligations or made payments on behalf of an investee.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has also adopted the amendments to IAS 28 Investments in Associates that addresses the dual application of IAS 28 and IFRS 9 (see below) when equity method losses are applied against Long-Term Interests (LTI). The amendments provide the annual sequence in which both standards are to be applied in such a case. The Group has applied the equity method losses to the LTIs presented as part of Investments held at fair value subsequent to remeasuring such investments to their fair value at balance sheet date.</span></div>
CY2022 ifrs-full Description Of Accounting Policy For Financial Instruments Explanatory
DescriptionOfAccountingPolicyForFinancialInstrumentsExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Instruments </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Classification </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group classifies its financial assets in the following measurement categories:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Those to be measured subsequently at fair value (either through other comprehensive income, or through profit or loss), and</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Those to be measured at amortized cost.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The classification depends on the Group’s business model for managing the financial assets and the contractual terms of the cash flows.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For assets measured at fair value, gains and losses are recorded in profit or loss. For investments in equity instruments that are not held for trading, this will depend on whether the Group has made an irrevocable election at the time of initial recognition to account for the equity investment at FVOCI. As of balance sheet dates, none of the Company's financial assets are accounted for as FVOCI.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Measurement </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">At initial recognition, the Group measures a financial asset at its fair value plus, in the case of a financial asset not at FVTPL, transaction costs that are directly attributable to the acquisition of the financial asset. Transaction costs of financial assets that are carried at FVTPL are expensed.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group assesses on a forward-looking basis the expected credit losses associated with its debt instruments carried at amortized cost. For trade receivables, the Group applies the simplified approach permitted by IFRS 9, which requires expected lifetime losses to be recognized from initial recognition of the receivables.</span></div>
CY2022 ifrs-full Description Of Accounting Policy For Financial Assets Explanatory
DescriptionOfAccountingPolicyForFinancialAssetsExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s financial assets consist of cash and cash equivalents, investments in debt securities, trade and other receivables, notes, restricted cash deposits and investments in equity securities. The Group’s financial assets are virtually all classified into the following categories: investments held at fair value, notes, trade and other receivables, short-term investments and cash and cash equivalents. The Group determines the classification of financial assets at initial recognition depending on the purpose for which the financial assets were acquired.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value are investments in equity instruments that are not held for trading. Such investments consist of the Group's minority interest holdings where the Group has no significant influence or preferred share investments in the Group's associates that are not providing access to returns underlying ownership interests. These financial assets are initially measured at fair value and subsequently re-measured at fair value at each reporting date. The Company elects if the gain or loss will be recognized in Other Comprehensive Income/(Loss) or through profit and loss on an instrument by instrument basis. The Company has elected to record the changes in fair values for the financial assets falling under this category through profit and loss. Please refer to Note 5.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Changes in the fair value of financial assets at FVTPL are recognized in other income/(expense) in the Consolidated Statements of Comprehensive Income/(Loss) as applicable. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The notes from an associate, since their contractual terms do not consist solely of cash flow payments of principal and interest on the principal amount outstanding, such notes are initially and subsequently measured at fair value, with changes in fair value recognized through profit and loss.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short term investments consist of short-term US treasury bills that are held to maturity. The contractual terms consist solely of payment of the principal and the Group's business model is to hold the treasury bills to maturity. As such, such short term </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">investments are recorded at amortized cost. As of balance sheet date amortized cost approximated the fair value of such short-term investments.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables are non-derivative financial assets with fixed and determinable payments that are not quoted on active markets. These financial assets are carried at the amounts expected to be received less any expected lifetime losses. Such losses are determined taking into account previous experience, credit rating and economic stability of counterparty and economic conditions. When a trade receivable is determined to be uncollectible, it is written off against the available provision. As of balance sheet date, The Group did not incur or record any such expected lifetime losses. Trade and other receivables are included in current assets, unless maturities are greater than 12 months after the end of the reporting period.</span></div>
CY2022 ifrs-full Revenue
Revenue
15618000 usd
CY2022 ifrs-full Description Of Accounting Policy For Financial Liabilities Explanatory
DescriptionOfAccountingPolicyForFinancialLiabilitiesExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Liabilities </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s financial liabilities consist of trade and other payables, subsidiary notes payable, long-term loan, preferred shares, and warrant liability. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrant liabilities are initially recognized at fair value. After initial recognition, these financial liabilities are re-measured at FVTPL using an appropriate valuation technique. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable without embedded derivatives and the long-term loan are accounted for at amortized cost.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The majority of the Group’s subsidiaries have preferred shares and certain notes payable with embedded derivatives, which are classified as current liabilities. When the Group has preferred shares and notes with embedded derivatives that qualify for bifurcation, the Group has elected to account for the entire instrument as FVTPL after determining under IFRS 9 that the instrument qualifies to be accounted for under such FVTPL method.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group derecognizes a financial liability when its contractual obligations are discharged, cancelled or expire.</span></div>
CY2022 ifrs-full Description Of Accounting Policy For Recognition Of Revenue
DescriptionOfAccountingPolicyForRecognitionOfRevenue
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">IFRS 15, Revenue from Contracts with Customers </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The standard establishes a five-step principle-based approach for revenue recognition and is based on the concept of recognizing an amount that reflects the consideration for performance obligations only when they are satisfied and the control of goods or services is transferred.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The majority of the Group’s contract revenue is generated from licenses and services, some of which are part of collaboration arrangements. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Management reviewed contracts where the Group received consideration in order to determine whether or not they should be accounted for in accordance with IFRS 15. To date, PureTech has entered into transactions that generate revenue and meet the scope of either IFRS 15 or IAS 20 Accounting for Government Grants. Contract revenue is recognized at either a point-in-time or over time, depending on the nature of the performance obligations.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group accounts for agreements that meet the definition of IFRS 15 by applying the following five step model:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Identify the contract(s) with a customer – A contract with a customer exists when (i) the Group enters into an enforceable contract with a customer that defines each party’s rights regarding the goods or services to be transferred and identifies the payment terms related to those goods or services, (ii) the contract has commercial substance and, (iii) the Group determines that collection of substantially all consideration for goods or services that are transferred is probable based on the customer’s intent and ability to pay the promised consideration.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Identify the performance obligations in the contract – Performance obligations promised in a contract are identified based on the goods or services that will be transferred to the customer that are both capable of being distinct, whereby the customer can benefit from the good or service either on its own or together with other resources that are readily available from third parties or from the Group, and are distinct in the context of the contract, whereby the transfer of the goods or services is separately identifiable from other promises in the contract.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Determine the transaction price – The transaction price is determined based on the consideration to which the Group will be entitled in exchange for transferring goods or services to the customer. To the extent the transaction price includes variable consideration, the Group estimates the amount of variable consideration that should be included in the transaction price utilizing either the expected value method or the most likely amount method depending on the nature of the variable consideration. Variable consideration is included in the transaction price if, in the Group’s judgement, it is probable that a significant future reversal of cumulative revenue under the contract will not occur. </span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Allocate the transaction price to the performance obligations in the contract – If the contract contains a single performance obligation, the entire transaction price is allocated to the single performance obligation. Contracts that contain multiple performance obligations require an allocation of the transaction price to each performance obligation based on a relative standalone selling price basis. </span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Recognize revenue when (or as) the Group satisfies a performance obligation – The Group satisfies performance obligations either over time or at a point in time as discussed in further detail below. Revenue is recognized at the time the related performance obligation is satisfied by transferring a promised good or service to a customer.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue generated from services agreements (typically where licenses and related services were combined into one performance obligation) is determined to be recognized over time when it can be determined that the services meet one of the following: (a) the customer simultaneously receives and consumes the benefits provided by the entity’s performance as the entity performs; (b) the entity’s performance creates or enhances an asset that the customer controls as the asset is created or enhanced; or (c) the entity’s performance does not create an asset with an alternative use to the entity and the entity has an enforceable right to payment for performance completed to date.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">It was determined that the Group has contracts that meet criteria (a), since the customer simultaneously receives and consumes the benefits provided by the Company’s performance as the Company performs. Therefore revenue is recognized over time using the input method based on costs incurred to date as compared to total contract costs. The Company believes that in research and development service type agreements using costs incurred to date represents the most faithful depiction of the entity’s performance towards complete satisfaction of a performance obligation.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue from licenses that are not part of a combined performance obligation are recognized at a point in time due to the licenses relating to intellectual property that has significant stand-alone functionality and as such represent a right to use the entity's intellectual property as it exists at the point in time at which the license is granted.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Royalty income received in respect of licensing agreements is recognized as the related third party sales in the licensee occur.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amounts that are receivable or have been received per contractual terms but have not been recognized as revenue since performance has not yet occurred or has not yet been completed are recorded as deferred revenue. The Company classifies as non-current deferred revenue amounts received for which performance is expected to occur beyond one year or one operating cycle.</span></div>
CY2022 ifrs-full Description Of Accounting Policy For Government Grants
DescriptionOfAccountingPolicyForGovernmentGrants
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant Income </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company recognizes grants from governmental agencies as grant income in the Consolidated Statement of Comprehensive Income/(Loss), gross of the expenditures that were related to obtaining the grant, when there is reasonable assurance that the Company will comply with the conditions within the grant agreement and there is reasonable assurance that payments under the grants will be received. The Company evaluates the conditions of each grant as of each reporting date to ensure that the Company has reasonable assurance of meeting the conditions of each grant arrangement and that it is expected that the grant payment will be received as a result of meeting the necessary conditions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company submits qualifying expenses for reimbursement after the Company has incurred the research and development expense. The Company records an unbilled receivable upon incurring such expenses. In cases were grant income is received prior to the expenses being incurred or recognized, the amounts received are deferred until the related expense is incurred and/or recognized. Grant income is recognized in the Consolidated Statements of Comprehensive Income/(Loss) at the time in which the Company recognizes the related reimbursable expense for which the grant is intended to compensate.</span></div>
CY2022 ifrs-full Description Of Accounting Policy For Functional Currency Explanatory
DescriptionOfAccountingPolicyForFunctionalCurrencyExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Functional and Presentation Currency </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">These consolidated financial statements are presented in United States dollars (“US dollars”). The functional currency of all members of the Group is the U.S. dollar. The Group's share in foreign exchange differences in associates were reported in Other Comprehensive Income/(Loss).</span></div>
CY2022 ifrs-full Description Of Accounting Policy For Foreign Currency Translation Explanatory
DescriptionOfAccountingPolicyForForeignCurrencyTranslationExplanatory
Foreign Currency Transactions in foreign currencies are translated to the respective functional currencies of Group entities at the foreign exchange rate ruling at the date of the transaction. Monetary assets and liabilities denominated in foreign currencies at the balance sheet date are retranslated to the functional currency at the foreign exchange rate ruling at that date. Foreign exchange differences arising on remeasurement are recognized in the Consolidated Statement of Comprehensive Income/(Loss). Non-monetary assets and liabilities that are measured in terms of historical cost in a foreign currency are translated using the exchange rate at the date of the transaction.
CY2022 ifrs-full Description Of Accounting Policy For Restricted Cash And Cash Equivalents Explanatory
DescriptionOfAccountingPolicyForRestrictedCashAndCashEquivalentsExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and Cash Equivalents </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and cash equivalents include all highly liquid instruments with original maturities of three months or less.</span></div>
CY2021 ifrs-full Revenue
Revenue
17388000 usd
CY2022 ifrs-full Description Of Accounting Policy For Issued Capital Explanatory
DescriptionOfAccountingPolicyForIssuedCapitalExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share Capital </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Ordinary shares are classified as equity. The Group's equity is comprised of share capital, share premium, merger reserve, other reserve, translation reserve, and retained earnings/accumulated deficit.</span></div>
CY2022 ifrs-full Description Of Accounting Policy For Treasury Shares Explanatory
DescriptionOfAccountingPolicyForTreasurySharesExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Treasury Shares</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Treasury shares are recognized at cost and are deducted from shareholders' equity. No gain or loss is recognized in profit and loss for the purchase, sale, re-issue or cancellation of the Company's own equity shares</span></div>
CY2022 ifrs-full Description Of Accounting Policy For Property Plant And Equipment Explanatory
DescriptionOfAccountingPolicyForPropertyPlantAndEquipmentExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Property and Equipment </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Property and equipment is stated at cost less accumulated depreciation and any accumulated impairment losses. Cost includes expenditures that are directly attributable to the acquisition of the asset. Assets under construction represent leasehold improvements and machinery and equipment to be used in operations or research and development activities. When parts of an item of property and equipment have different useful lives, they are accounted for as separate items (major components) of property and equipment. Depreciation is calculated using the straight-line method over the estimated useful life of the related asset: </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:48.821%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:48.979%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Laboratory and manufacturing equipment</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2-8 years</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Furniture and fixtures</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7 years</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Computer equipment and software</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1-5 years</span></div></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Leasehold improvements</span></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5-10 years, or the remaining term of the lease, if shorter</span></div></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation methods, useful lives and residual values are reviewed at each balance sheet date.</span></div>
CY2022 ifrs-full Description Of Accounting Policy For Intangible Assets Other Than Goodwill Explanatory
DescriptionOfAccountingPolicyForIntangibleAssetsOtherThanGoodwillExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Intangible Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Intangible assets, which include purchased patents and licenses with finite useful lives, are carried at historical cost less accumulated amortization, if amortization has commenced. Intangible assets with finite lives are amortized from the time they are available for their intended use. Amortization is calculated using the straight-line method to allocate the costs of patents and licenses over their estimated useful lives. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development intangible assets, which are still under development and have accordingly not yet obtained marketing approval, are presented as In-Process Research and Development (IPR&amp;D). IPR&amp;D is not amortized since it is not yet available for its intended use, but it is evaluated for potential impairment on an annual basis or more frequently when facts and circumstances warrant.</span></div>
CY2022 ifrs-full Description Of Accounting Policy For Impairment Of Nonfinancial Assets Explanatory
DescriptionOfAccountingPolicyForImpairmentOfNonfinancialAssetsExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Impairment of Non-Financial Assets </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group reviews the carrying amounts of its property and equipment and intangible assets at each reporting date to determine whether there are indicators of impairment. If any such indicators of impairment exist, then an asset’s recoverable amount is estimated. The recoverable amount is the higher of an asset’s fair value less cost of disposal and value in use.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company’s IPR&amp;D intangible assets are not yet available for their intended use. As such, they are tested for impairment at least annually. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">An impairment loss is recognized when an asset’s carrying amount exceeds its recoverable amount. For the purposes of impairment testing, assets are grouped at the lowest levels for which there are largely independent cash flows. If a non- financial asset instrument is impaired, an impairment loss is recognized in the Consolidated Statements of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments in associates are considered impaired if, and only if, objective evidence indicates that one or more events, which occurred after the initial recognition, have had an impact on the future cash flows from the net investment and that impact can be reliably estimated. If an impairment exists the Company measures an impairment by comparing the carrying value of the net investment in the associate to its recoverable amount and recording any excess as an impairment loss. See Note 6 for impairment recorded in respect of an investment in associate during the year ended December 31, 2022.</span></div>
CY2022 ifrs-full Description Of Accounting Policy For Employee Benefits Explanatory
DescriptionOfAccountingPolicyForEmployeeBenefitsExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Employee Benefits </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Short-Term Employee Benefits </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term employee benefit obligations are measured on an undiscounted basis and expensed as the related service is provided. A liability is recognized for the amount expected to be paid if the Group has a present legal or constructive obligation due to past service provided by the employee, and the obligation can be estimated reliably.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Defined Contribution Plans </span></div>A defined contribution plan is a post-employment benefit plan under which an entity pays fixed contributions into a separate entity and has no legal or constructive obligation to pay further amounts. Obligations for contributions to defined contribution plans are recognized as an employee benefit expense in the periods during which related services are rendered by employees. Prepaid contributions are recognized as an asset to the extent that a cash refund or a reduction in future payments is available.
CY2022 ifrs-full Description Of Accounting Policy For Sharebased Payment Transactions Explanatory
DescriptionOfAccountingPolicyForSharebasedPaymentTransactionsExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Share-based Payments </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment arrangements, in which the Group receives goods or services as consideration for its own equity instruments, are accounted for as equity-settled share-based payment transactions (except certain restricted stock units - see below) in accordance with IFRS 2, regardless of how the equity instruments are obtained by the Group. The grant date fair value of employee share-based payment awards is recognized as an expense with a corresponding increase in equity over the requisite service period related to the awards. The amount recognized as an expense is adjusted to reflect the actual number of awards for which the related service and non-market performance conditions are expected to be met, such that the amount ultimately recognized as an expense is based on the number of awards that do meet the related service and non-market performance conditions at the vesting date. For share-based payment awards with market conditions, the grant date fair value is measured to reflect such conditions and there is no true-up for differences between expected and actual outcomes.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain restricted stock units are treated as liability settled awards starting in 2021. Such awards are remeasured at every reporting date until settlement date and are recognized as compensation expense over the requisite service period. Differences in remeasurement are recognized in profit and loss. The cumulative cost that will ultimately be recognized in respect of these awards will equal to the amount at settlement. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the awards is measured using option pricing models and other appropriate models, which take into account the terms and conditions of the awards granted. See further details in Note 8.</span></div>
CY2022 ifrs-full Description Of Accounting Policy For Research And Development Expense Explanatory
DescriptionOfAccountingPolicyForResearchAndDevelopmentExpenseExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Development Costs </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expenditures on research activities are recognized as incurred in the Consolidated Statements of Comprehensive Income/(Loss). In accordance with IAS 38 development costs are capitalized only if the expenditure can be measured reliably, the product or process is technically and commercially feasible, future economic benefits are probable, the Group can demonstrate its ability to use or sell the intangible asset, the Group intends to and has sufficient resources to complete development and to use or sell the asset, and it is able to measure reliably the expenditure attributable to the intangible asset during its development. The point at which technical feasibility is determined to have been reached is, generally, when regulatory approval has been received where applicable. Management determines that commercial viability has been reached </span></div>when a clear market and pricing point have been identified, which may coincide with achieving meaningful recurring sales. Otherwise, the development expenditure is recognized as incurred in the Consolidated Statements of Comprehensive Income/(Loss). As of balance sheet date the Group has not capitalized any development costs.
CY2022 ifrs-full Description Of Accounting Policy For Provisions Explanatory
DescriptionOfAccountingPolicyForProvisionsExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Provisions </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">A provision is recognized in the Consolidated Statements of Financial Position when the Group has a present legal or constructive obligation due to a past event that can be reliably measured, and it is probable that an outflow of economic benefits will be required to settle the obligation. Provisions are determined by discounting the expected future cash flows at a pre-tax rate that reflects risks specific to the liability.</span></div>
CY2020 ifrs-full Revenue
Revenue
11768000 usd
CY2022 ifrs-full Disclosure Of Disaggregation Of Revenue From Contracts With Customers Explanatory
DisclosureOfDisaggregationOfRevenueFromContractsWithCustomersExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group disaggregates contract revenue in a manner that depicts how the nature, amount, timing, and uncertainty of revenue and cash flows are affected by economic factors. The Group disaggregates revenue based on contract revenue or grant revenue, and further disaggregates contract revenue based on the transfer of control of the underlying performance obligations.</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:63.330%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Timing of contract revenue recognition</span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transferred at a point in time – Licensing Income</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">527</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,809 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,054 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transferred over time</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,563</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,171 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,286 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,090</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,979 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,341 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:13.5pt;text-indent:-13.5pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    2022 – Attributed to Non-Controlled Founded Entities segment ( $19 thousand) and to Parent Company and Other ($509 thousand); 2021 – Attributed to the Internal segment ($6,500 thousand), Non-Controlled Founded Entities segment ($74 thousand), and to Parent Company and Other ($235 thousand); 2020 – Attributed to Parent Company and Other. See note 4, Segment information. </span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    2022 – Attributed to Controlled Founded Entities segment ($1,500 thousand) and to Non-Controlled Founded Entities segment ($63 thousand ); 2021 – Attributed to Internal segment ($1,629 thousand), Non-Controlled Founded Entities segment ($41 thousand), and to Controlled Founded Entities segment ($1,500 thousand). 2020 – Attributed to Internal segment ($5,297 thousand), Controlled Founded Entities segment ($896 thousand), and to Non-Controlled Founded Entities segment ($93 thousand). See Note 4, Segment Information.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:63.330%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Customers over 10% of revenue</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer A</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,518 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer B</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,500</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">896 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer C</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,043 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer D</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,250 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,736 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer E</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer F</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">509</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,009</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,750 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,193 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>
CY2022 ifrs-full Revenue From Contracts With Customers
RevenueFromContractsWithCustomers
2090000 usd
CY2022 ifrs-full Description Of Accounting Policy For Leases Explanatory
DescriptionOfAccountingPolicyForLeasesExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Leases</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group leases real estate (and some minor equipment) for use in operations. These leases generally have lease terms of 1 to 10 years. The Group includes options that are reasonably certain to be exercised as part of the determination of the lease term. The group determines if an arrangement is a lease at inception of the contract in accordance with guidance detailed in IFRS 16. ROU assets represent the Group’s right to use an underlying asset for the lease term and lease liabilities represent the Group's obligation to make lease payments arising from the lease. Operating lease ROU assets and lease liabilities are recognized at commencement date based on the present value of the lease payments over the lease term. As most of the Group's leases do not provide an implicit rate, The Group used its estimated incremental borrowing rate, based on information available at commencement date, in determining the present value of future payments. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s leases are virtually all leases of real estate.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has elected to account for lease payments as an expense on a straight-line basis over the life of the lease for: </span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Leases with a term of 12 months or less and containing no purchase options; and </span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Leases where the underlying asset has a value of less than $5,000. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The right-of-use asset is depreciated on a straight-line basis and the lease liability gives rise to an interest charge. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Further information regarding the subleases, right of use asset and lease liability can be found in Note 21.</span></div>
CY2022 ifrs-full Description Of Accounting Policy For Finance Income And Costs Explanatory
DescriptionOfAccountingPolicyForFinanceIncomeAndCostsExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance Income and Finance Costs </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income is comprised of income on funds invested in U.S. treasuries, income on money market funds and income on a finance lease. Financing income is recognized as it is earned. Finance costs comprise mainly of loan, notes and lease liability interest expenses and the changes in the fair value of financial liabilities carried at FVTPL (such changes can consist of finance income when the fair value of such financial liabilities decreases).</span></div>
CY2022 ifrs-full Description Of Accounting Policy For Income Tax Explanatory
DescriptionOfAccountingPolicyForIncomeTaxExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax on the profit or loss for the year comprises current and deferred income tax. In accordance with IAS 12, tax is recognized in the Consolidated Statements of Comprehensive Income/(Loss) except to the extent that it relates to items recognized directly in equity.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current income tax is the expected tax payable or receivable on the taxable income or loss for the year, using tax rates enacted or substantially enacted at the reporting date, and any adjustment to tax payable in respect of previous years.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax is recognized due to temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for taxation purposes. Deferred tax assets are recognized for unused tax losses, unused tax credits and deductible temporary differences to the extent that it is probable that future taxable profits will be available against which they can be used. Deferred tax assets with respect to investments in associates are recognized only to the extent that it is probable the temporary difference will reverse in the foreseeable future and taxable profit will be available against which the temporary difference can be utilised. Deferred tax assets are reviewed at each reporting date and are reduced to the extent that it is no longer probable that the related tax benefit will be realized.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax is measured at the tax rates that are expected to be applied to temporary differences when they reverse, using tax rates enacted or substantively enacted at the reporting date.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred income tax assets and liabilities are offset when there is a legally enforceable right to offset current tax assets against current tax liabilities and when the deferred income tax assets and liabilities relate to income taxes levied by the same taxation authority on either the same taxable entity or different taxable entities where there is an intention to settle the balances on a net basis.</span></div>
CY2022 ifrs-full Description Of Accounting Policy For Fair Value Measurement Explanatory
DescriptionOfAccountingPolicyForFairValueMeasurementExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair Value Measurements </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s accounting policies require that certain financial assets and certain financial liabilities be measured at their fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group uses valuation techniques that are appropriate in the circumstances and for which sufficient data are available to measure fair value, maximizing the use of relevant observable inputs and minimizing the use of unobservable inputs. Fair values are categorized into different levels in a fair value hierarchy based on the inputs used in the valuation techniques as follows:</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 1: quoted prices (unadjusted) in active markets for identical assets or liabilities.</span></div><div style="padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 2: inputs other than quoted prices included in Level 1 that are observable for the asset or liability, either directly (i.e. as prices) or indirectly (i.e. derived from prices).</span></div><div style="margin-bottom:5pt;padding-left:11.34pt;text-indent:-11.34pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">•</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%;padding-left:7.09pt">Level 3: inputs for the asset or liability that are not based on observable market data (unobservable inputs).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group recognizes transfers between levels of the fair value hierarchy at the end of the reporting period during which the change has occurred.</span></div>The carrying amount of cash and cash equivalents, accounts receivable, restricted cash, deposits, accounts payable, accrued expenses and other current liabilities in the Group’s Consolidated Statements of Financial Position approximates their fair value because of the short maturities of these instruments.
CY2022 ifrs-full Description Of Accounting Policy For Segment Reporting Explanatory
DescriptionOfAccountingPolicyForSegmentReportingExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating Segments </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating segments are reported in a manner that is consistent with the internal reporting provided to the chief operating decision maker (“CODM”). The CODM reviews discrete financial information for the operating segments in order to assess their performance and is responsible for making decisions about resources allocated to the segments. The CODM has been identified as the Group’s Directors.</span></div>
CY2021 ifrs-full Revenue From Contracts With Customers
RevenueFromContractsWithCustomers
9979000 usd
CY2020 ifrs-full Revenue From Contracts With Customers
RevenueFromContractsWithCustomers
8341000 usd
CY2022 ifrs-full Description Of Expected Impact Of Initial Application Of New Standards Or Interpretations
DescriptionOfExpectedImpactOfInitialApplicationOfNewStandardsOrInterpretations
New Standards and Interpretations Not Yet Adopted <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">A number of new standards, interpretations, and amendments to existing standards are effective for annual periods commencing on or after January 1, 2023 and have not been applied in preparing the consolidated financial information. The Company’s assessment of the impact of these new standards and interpretations is set out below.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effective January 1, 2023, the definition of accounting estimates has been amended as an amendment to IAS 8 Accounting Policies, Changes in Accounting Estimates and Errors. The amendments clarify how companies should distinguish changes in accounting policies from changes in accounting estimates. The distinction is important because changes in accounting estimates are applied prospectively only to future transactions and future events, but changes in accounting policies are generally also applied retrospectively to past transactions and other past events. This amendment is not expected to have an impact on the Group's financial statements.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effective January 1, 2023, IAS 1 has been amended to clarify that liabilities are classified as either current or non-current, depending on the rights that exist at the end of the reporting period. Classification is unaffected by the expectations of the entity or events after the reporting date. The Company does not expect this amendment will have a material impact on its financial statements.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effective January 1, 2023, IAS 12 is amended to narrow the scope of the initial recognition exemption (IRE) so that it does not apply to transactions that give rise to equal and offsetting temporary differences. As a result, companies will need to recognise a deferred tax asset and a deferred tax liability for temporary differences arising on initial recognition of a lease and a decommissioning provision. The amendment is not expected to have an impact on the Group's financial statements as the Group has already recognized a deferred tax asset and deferred tax liability that arose on initial recognition of its leases (the Group does not have decommissioning provisions).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">None of the other new standards, interpretations, and amendments are applicable to the Company’s financial statements and therefore will not have an impact on the Company.</span></div>
CY2022 ifrs-full Description Of Expected Impact Of Initial Application Of New Standards Or Interpretations
DescriptionOfExpectedImpactOfInitialApplicationOfNewStandardsOrInterpretations
New Standards and Interpretations Not Yet Adopted <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">A number of new standards, interpretations, and amendments to existing standards are effective for annual periods commencing on or after January 1, 2023 and have not been applied in preparing the consolidated financial information. The Company’s assessment of the impact of these new standards and interpretations is set out below.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effective January 1, 2023, the definition of accounting estimates has been amended as an amendment to IAS 8 Accounting Policies, Changes in Accounting Estimates and Errors. The amendments clarify how companies should distinguish changes in accounting policies from changes in accounting estimates. The distinction is important because changes in accounting estimates are applied prospectively only to future transactions and future events, but changes in accounting policies are generally also applied retrospectively to past transactions and other past events. This amendment is not expected to have an impact on the Group's financial statements.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effective January 1, 2023, IAS 1 has been amended to clarify that liabilities are classified as either current or non-current, depending on the rights that exist at the end of the reporting period. Classification is unaffected by the expectations of the entity or events after the reporting date. The Company does not expect this amendment will have a material impact on its financial statements.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effective January 1, 2023, IAS 12 is amended to narrow the scope of the initial recognition exemption (IRE) so that it does not apply to transactions that give rise to equal and offsetting temporary differences. As a result, companies will need to recognise a deferred tax asset and a deferred tax liability for temporary differences arising on initial recognition of a lease and a decommissioning provision. The amendment is not expected to have an impact on the Group's financial statements as the Group has already recognized a deferred tax asset and deferred tax liability that arose on initial recognition of its leases (the Group does not have decommissioning provisions).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">None of the other new standards, interpretations, and amendments are applicable to the Company’s financial statements and therefore will not have an impact on the Company.</span></div>
CY2022 ifrs-full Disclosure Of Revenue Explanatory
DisclosureOfRevenueExplanatory
Revenue <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue recorded in the Consolidated Statement of Comprehensive Income/(Loss) consists of the following:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:63.330%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,090</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,979 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,341 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant income</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,528</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,409 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,427 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total revenue</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15,618</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,388 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,768 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">All amounts recorded in contract revenue were generated in the United States. For the years ended December 31, 2022, 2021 and 2020 contract revenue includes royalties received from an associate in the amount of $509 thousand, $231 thousand, and $54 thousand, respectively.</span></div>Primarily all of the Company’s other contracts for the years ended December 31, 2022, 2021 and 2020 were determined to have a single performance obligation which consists of a combined deliverable of license to intellectual property and research and development services (not including the license acquired by Imbrium upon option exercise – see below). Therefore, for such contracts, revenue is recognized over time based on the input method which the Company believes is a faithful depiction of the transfer of goods and services. Progress is measured based on costs incurred to date as compared to total projected costs. Payments for such contracts are primarily made up front on a periodic basis.<div style="margin-bottom:5pt;margin-top:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2021, the company received a $6.5 million payment from Imbrium Therapeutics, Inc. following the exercise of the option to acquire an exclusive license for the Initial Product Candidate, as defined in the agreement. Since the license transferred was a functional license, revenue from the option exercise was recognized at a point in time upon transfer of the license, which occurred during the year ended December 31, 2021.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2020, the Company received a $2.0 million milestone payment from Karuna Therapeutics, Inc. following initiation of its KarXT Phase 3 clinical study pursuant to the Exclusive Patent License Agreement between PureTech and Karuna. This milestone was recognized as revenue during the year ended December 31, 2020.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disaggregated Revenue</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group disaggregates contract revenue in a manner that depicts how the nature, amount, timing, and uncertainty of revenue and cash flows are affected by economic factors. The Group disaggregates revenue based on contract revenue or grant revenue, and further disaggregates contract revenue based on the transfer of control of the underlying performance obligations.</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:63.330%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Timing of contract revenue recognition</span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transferred at a point in time – Licensing Income</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">527</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,809 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,054 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transferred over time</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,563</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,171 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,286 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,090</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,979 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,341 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:13.5pt;text-indent:-13.5pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    2022 – Attributed to Non-Controlled Founded Entities segment ( $19 thousand) and to Parent Company and Other ($509 thousand); 2021 – Attributed to the Internal segment ($6,500 thousand), Non-Controlled Founded Entities segment ($74 thousand), and to Parent Company and Other ($235 thousand); 2020 – Attributed to Parent Company and Other. See note 4, Segment information. </span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    2022 – Attributed to Controlled Founded Entities segment ($1,500 thousand) and to Non-Controlled Founded Entities segment ($63 thousand ); 2021 – Attributed to Internal segment ($1,629 thousand), Non-Controlled Founded Entities segment ($41 thousand), and to Controlled Founded Entities segment ($1,500 thousand). 2020 – Attributed to Internal segment ($5,297 thousand), Controlled Founded Entities segment ($896 thousand), and to Non-Controlled Founded Entities segment ($93 thousand). See Note 4, Segment Information.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:63.330%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Customers over 10% of revenue</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer A</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,518 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer B</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,500</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">896 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer C</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,043 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer D</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,250 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,736 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer E</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Customer F</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">509</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,009</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,750 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,193 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accounts receivables represent rights to consideration in exchange for products or services that have been transferred by the Group, when payment is unconditional and only the passage of time is required before payment is due. Accounts receivables do not bear interest and are recorded at the invoiced amount. Accounts receivable are included within Trade and other receivables on the Consolidated Statement of Financial Position.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract liabilities represent the Group’s obligation to transfer products or services to a customer for which consideration has been received, or for which an amount of consideration is due from the customer. Contract liabilities are included within deferred revenue on the Consolidated Statement of Financial Position.</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:75.187%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.757%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Contract Balances</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accounts receivable</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">606</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">704 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred revenue – short term</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">65 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2022, $65 thousand of revenue was recognized from deferred revenue outstanding at December 31, 2021. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Remaining performance obligations represent the transaction price of unsatisfied or partially satisfied performance obligations within contracts with an original expected contract term that is greater than one year and for which fulfillment of the contract has started as of the end of the reporting period. The aggregate amount of transaction consideration allocated to remaining performance obligations as of December 31, 2022, was nil. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2022 the deferred revenue balance related entirely to deferred grant income.</span></div>
CY2022 ifrs-full Disclosure Of Revenue From Contracts With Customers Explanatory
DisclosureOfRevenueFromContractsWithCustomersExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue recorded in the Consolidated Statement of Comprehensive Income/(Loss) consists of the following:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:63.330%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,090</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,979 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,341 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant income</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,528</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,409 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,427 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total revenue</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15,618</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,388 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,768 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>
CY2022 ifrs-full Revenue From Contracts With Customers
RevenueFromContractsWithCustomers
2090000 usd
CY2021 ifrs-full Revenue From Contracts With Customers
RevenueFromContractsWithCustomers
9979000 usd
CY2020 ifrs-full Revenue From Contracts With Customers
RevenueFromContractsWithCustomers
8341000 usd
CY2022 ifrs-full Revenue From Government Grants
RevenueFromGovernmentGrants
13528000 usd
CY2021 ifrs-full Revenue From Government Grants
RevenueFromGovernmentGrants
7409000 usd
CY2022Q4 ifrs-full Receivables From Contracts With Customers
ReceivablesFromContractsWithCustomers
606000 usd
CY2021Q4 ifrs-full Receivables From Contracts With Customers
ReceivablesFromContractsWithCustomers
704000 usd
CY2022Q4 ifrs-full Current Contract Liabilities
CurrentContractLiabilities
0 usd
CY2021Q4 ifrs-full Current Contract Liabilities
CurrentContractLiabilities
65000 usd
CY2022 ptv Revenue Recognized On Deferred Revenue Outstanding At Prior Year End
RevenueRecognizedOnDeferredRevenueOutstandingAtPriorYearEnd
65000 usd
CY2022 ifrs-full Disclosure Of Entitys Reportable Segments Explanatory
DisclosureOfEntitysReportableSegmentsExplanatory
Segment Information<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basis for Segmentation </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Directors are the Group’s strategic decision-makers. The Group’s operating segments are reported based on the financial information provided to the Directors periodically for the purposes of allocating resources and assessing performance. The Group has determined that each entity is representative of a single operating segment as the Directors monitor the financial results at this level. When identifying the reportable segments the Group has determined that it is appropriate to aggregate multiple operating segments into a single reportable segment given the high level of operational and financial similarities across the entities.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has identified multiple reportable segments as presented below. There was no change to reportable segments in 2022, except for the transfer of Sonde Health, Inc. to the Non-Controlled Founded Entities segment due to the deconsolidation of Sonde Health, Inc (Sonde) on May 25, 2022. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Non-Controlled Founded Entities segment includes Sonde Health, Inc. which was deconsolidated on May 25, 2022. Segment results incorporate the operational results of Sonde Health, Inc. to the date of deconsolidation. Following the date of deconsolidation, the Company accounts for its investment in Sonde Health, Inc. at the parent level, and therefore the results associated with investment activity following the date of deconsolidation (including the Group's share in Sonde losses) is included in the Parent Company and Other section.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company has revised in these financial statements the prior year financial information to conform to the presentation as of and for the year ending December 31, 2022 to include Sonde in the Non-Controlled Founded Entities segment. The change in segments reflects how the Company’s Board of Directors reviews the Group’s results, allocates resources and assesses performance of the Group at this time.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Virtually all of the revenue and profit generating activities of the Group are generated within the United States and accordingly, no geographical disclosures are provided.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Internal</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Internal segment (the “Internal segment”), is advancing Wholly Owned Programs which are focused on treatments for patients with devastating diseases. The Internal segment is comprised of the technologies that are wholly owned and will be advanced through either PureTech Health funding or non-dilutive sources of financing in the near-term. The operational management of the Internal segment is conducted by the PureTech Health team, which is responsible for the strategy, business development, and research and development. As of December 31, 2022, this segment included PureTech LYT, PureTech LYT-100 and Alivio Therapeutics, Inc.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Controlled Founded Entities</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Controlled Founded Entity segment (the “Controlled Founded Entity segment”) is comprised of the Group’s subsidiaries that are currently consolidated operational subsidiaries that either have, or have plans to hire, independent management teams and currently have already raised third-party dilutive capital. These subsidiaries have active research and development programs and either have entered into or plan to seek an equity or debt investment partner, who will provide additional industry knowledge and access to networks, as well as additional funding to continue the pursued growth of the company. As of December 31, 2022, this segment included Entrega Inc., Follica Incorporated, and Vedanta Biosciences, Inc.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-Controlled Founded Entities</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Non-Controlled Founded Entities segment (the “Non-Controlled Founded Entities segment”) is comprised of the entities in respect of which PureTech Health no longer has control over the entity. Upon deconsolidation of an entity the segment disclosure is restated to reflect the change on a retrospective basis, as this constitutes a change in the composition of its reportable segments. The Non-Controlled Founded Entities segment includes Sonde Health Inc. which was deconsolidated on May 25, 2022.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Non-Controlled Founded Entities segment incorporates the operational results of the aforementioned entity to the date of deconsolidation. Following the date of deconsolidation, the Company accounts for its investment in each entity at the parent level, and therefore the results associated with investment activity (including the recognition of equity method income/ (losses)) following the date of deconsolidation is included in the Parent Company and Other section.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Parent Company and Other </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Parent Company and Other includes activities that are not directly attributable to the operating segments, such as the activities of the Parent, corporate support functions and certain research and development support functions that are not directly attributable to a strategic business segment as well as the elimination of intercompany transactions. Intercompany transactions between segments consist primarily of management fees charged from the Parent Company to the other segments. This section also captures the accounting for the Company’s holdings in entities for which control has been lost, which is inclusive of the following items: gain on deconsolidation, gain or loss on investments held at fair value, realized loss on sale of investments, the share of net income/ (loss) of associates accounted for using the equity method, gain on dilution of ownership interest in associate, impairment of investment in associate. As of December 31, 2022, this segment included PureTech Health plc, PureTech Health LLC, PureTech Management, Inc., PureTech Securities Corp. and PureTech Securities II Corp., as well as certain other dormant, inactive and shell entities.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Information About Reportable Segments: </span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:40.241%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.600%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.288%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.759%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Internal<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Controlled Founded Entities<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Non-Controlled Founded<br/>Entities<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Parent Company &amp; <br/>Other<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Consolidated<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Consolidated Statements of Comprehensive Income/(Loss)</span></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,500</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">81</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">509</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,090</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,826</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,702</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,528</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,826</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">12,202</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">81</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">509</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15,618</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(8,301)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(16,462)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,296)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(34,933)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(60,991)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(116,054)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(34,668)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(826)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(885)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(152,433)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total operating expense</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(124,355)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(51,130)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,122)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(35,817)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(213,425)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,251</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,251</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investment held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(32,060)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(32,060)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Realized loss on sale of investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(29,303)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(29,303)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(204)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,338</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,131</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total other income/(expense)</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(204)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(25,775)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(25,981)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">615</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">138,006</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,045)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,348</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">138,924</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associates accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(27,749)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(27,749)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on dilution of ownership interest in associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28,220</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28,220</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment of investment in associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(8,390)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(8,390)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) before taxes</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(121,118)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99,075</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,085)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(65,655)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(92,783)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) before taxes pre IFRS 9 fair value accounting, share-based payment expense, depreciation of tangible assets and amortization of intangible assets</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(114,255)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(32,468)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,079)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(57,452)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(206,254)</span></td><td style="border-right:0.25pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income/(costs) – IFRS 9 fair value accounting</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">140,056</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,993)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">137,063</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-right:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,136)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,703)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(8)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,852)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(14,699)</span></td><td style="border-right:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation of tangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,727)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,526)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,588)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,845)</span></td><td style="border-right:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of ROU assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,283)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,764)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,047)</span></td><td style="border-right:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of intangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1)</span></td><td style="border-right:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">55,719</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">55,719</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(121,118)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99,075</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,085)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(9,936)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(37,065)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(379)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(379)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(121,118)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99,075</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,085)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(10,316)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(37,444)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8pt;font-weight:700;line-height:120%">Total comprehensive income/(loss) attributable to:</span></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Owners of the Company</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(121,118)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">85,471</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,755)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(10,331)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(50,733)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-controlling interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,604</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(330)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,290</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="15" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">December 31, 2022 $000s</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Consolidated Statements of Financial Position:</span></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total assets</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">51,599</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,341</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">615,707</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">702,647</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:5.67pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total liabilities</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">271,186</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">76,635</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(192,763)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">155,057</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Net assets/(liabilities)</span></td><td colspan="2" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(219,587)</span></td><td style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(41,294)</span></td><td style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">808,470</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">547,589</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:1pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Parent Company and Other Includes eliminations of intercompany liabilities between the Parent Company and the reportable segments in the amount of $255.5 million.</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Non-Controlled Founded<br/>Entities<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Parent Company &amp;<br/>Other<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Consolidated<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated Statements of Comprehensive Income/(Loss)</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,129 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">115 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">235 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,979 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,253 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,156 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,409 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,382 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,656 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">115 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">235 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,388 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,673)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(17,504)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,225)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(27,797)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(57,199)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(65,444)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(40,667)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,116)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,244)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(110,471)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total Operating expenses</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(74,118)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(58,171)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,341)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(29,041)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(167,671)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investment held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">179,316 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">179,316 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Realized loss on sale of investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(20,925)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(20,925)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">70 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,523 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,593 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total other income/(expense)</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">70 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">159,914 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">159,983 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(16)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,528 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(784)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,679)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,050 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associate accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(73,703)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(73,703)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) before taxes </span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(64,753)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42,917)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,010)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">55,727 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(58,953)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(Loss)/income before taxes pre IFRS 9 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(60,368)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(44,335)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,248)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">63,628 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(47,323)</span></td><td style="border-right:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income/(costs) – IFRS 9 fair value accounting</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,322 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(716)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,606 </span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,066)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,224)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(32)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,628)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(13,950)</span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation of tangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,319)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,506)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(12)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,510)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,347)</span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of ROU assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,174)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,764)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,938)</span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of intangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2)</span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,756)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,756)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(64,753)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42,917)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,010)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51,971 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(62,709)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(64,753)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42,917)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,010)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51,971 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(62,709)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) attributable to:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Owners of the Company</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(64,657)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,283)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,574)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51,956 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(60,558)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-controlling interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(96)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,634)</span></td><td style="border-bottom:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(436)</span></td><td style="border-bottom:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15 </span></td><td style="border-bottom:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,151)</span></td><td style="border-bottom:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="15" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">December 31, 2021 $000s</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated Statements of Financial Position:</span></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total assets</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">125,726 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">64,508 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,765 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">754,007 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">946,006 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:5.67pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total liabilities</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">228,789 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">209,212 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19,645 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(95,787)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">361,859 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net (liabilities)/assets</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(103,063)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(144,704)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(17,880)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">849,794 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">584,147 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Parent Company and Other Includes eliminations of intercompany liabilities between the Parent Company and the reportable segments in the amount of $233.3 million.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The proportion of net assets shown above that is attributable to non-controlling interest is disclosed in Note 18. </span></div><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Non-Controlled Founded<br/>Entities<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Parent Company &amp;<br/>Other<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Consolidated<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated Statements of Comprehensive Loss</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,297 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">896 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">93 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,054 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,341 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,563 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,864 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,427 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,860 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,760 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">93 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,054 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,768 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,482)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,752)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,939)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(32,267)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(49,440)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45,346)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(33,152)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,128)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(234)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(81,859)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total operating expense</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(48,828)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(43,904)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,067)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(32,500)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(131,299)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investment held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">232,674 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">232,674 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Realized loss on sale of investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(54,976)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(54,976)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on disposal of assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(30)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">965 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,065 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">85 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">178,662 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">178,732 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,352)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(852)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(930)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,115)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associate accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(34,117)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(34,117)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) before taxes</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,964)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45,410)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,826)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">113,170 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,969 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(Loss)/income before taxes pre IAS 39 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(38,349)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(36,736)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,866)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">121,644 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">40,694 </span></td><td style="border-right:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income/(costs) – IFRS 9 fair value accounting</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,492)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(859)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,351)</span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,762)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,469)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(83)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,405)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,718)</span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation of tangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(854)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,528)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(17)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,547)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,945)</span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of ROU assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,186)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,523)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,709)</span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of intangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1)</span></td><td style="border-right:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(14,400)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(14,401)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,964)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45,411)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,826)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">98,769 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,568 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">469 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">469 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,964)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45,411)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,826)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99,238 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,037 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) attributable to:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Owners of the Company</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,773)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(44,506)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,519)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99,253 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,454 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-controlling interests</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(191)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(905)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(306)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,417)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table>
CY2022 ifrs-full Disclosure Of Operating Segments Explanatory
DisclosureOfOperatingSegmentsExplanatory
<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Information About Reportable Segments: </span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:40.241%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.600%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.288%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.759%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Internal<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Controlled Founded Entities<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Non-Controlled Founded<br/>Entities<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Parent Company &amp; <br/>Other<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Consolidated<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Consolidated Statements of Comprehensive Income/(Loss)</span></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,500</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">81</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">509</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,090</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,826</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,702</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,528</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,826</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">12,202</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">81</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">509</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15,618</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(8,301)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(16,462)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,296)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(34,933)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(60,991)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(116,054)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(34,668)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(826)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(885)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(152,433)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total operating expense</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(124,355)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(51,130)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,122)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(35,817)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(213,425)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,251</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,251</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investment held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(32,060)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(32,060)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Realized loss on sale of investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(29,303)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(29,303)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(204)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,338</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,131</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total other income/(expense)</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(204)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(25,775)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(25,981)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">615</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">138,006</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,045)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,348</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">138,924</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associates accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(27,749)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(27,749)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on dilution of ownership interest in associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28,220</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">28,220</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment of investment in associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(8,390)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(8,390)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) before taxes</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(121,118)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99,075</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,085)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(65,655)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(92,783)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) before taxes pre IFRS 9 fair value accounting, share-based payment expense, depreciation of tangible assets and amortization of intangible assets</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(114,255)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(32,468)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,079)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(57,452)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(206,254)</span></td><td style="border-right:0.25pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income/(costs) – IFRS 9 fair value accounting</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">140,056</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,993)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">137,063</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-right:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,136)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,703)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(8)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,852)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(14,699)</span></td><td style="border-right:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation of tangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,727)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,526)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,588)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,845)</span></td><td style="border-right:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of ROU assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,283)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,764)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,047)</span></td><td style="border-right:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of intangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1)</span></td><td style="border-right:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">55,719</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">55,719</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(121,118)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99,075</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,085)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(9,936)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(37,065)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(379)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(379)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(121,118)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99,075</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(5,085)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(10,316)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(37,444)</span></td><td style="border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8pt;font-weight:700;line-height:120%">Total comprehensive income/(loss) attributable to:</span></td><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Owners of the Company</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(121,118)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">85,471</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,755)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(10,331)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(50,733)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-controlling interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,604</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(330)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,290</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="15" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">December 31, 2022 $000s</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Consolidated Statements of Financial Position:</span></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total assets</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">51,599</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,341</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">615,707</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">702,647</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:5.67pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total liabilities</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">271,186</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">76,635</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(192,763)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">155,057</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Net assets/(liabilities)</span></td><td colspan="2" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(219,587)</span></td><td style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(41,294)</span></td><td style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">808,470</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">547,589</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000000;border-top:0.25pt solid #000000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:1pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Parent Company and Other Includes eliminations of intercompany liabilities between the Parent Company and the reportable segments in the amount of $255.5 million.</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Non-Controlled Founded<br/>Entities<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Parent Company &amp;<br/>Other<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Consolidated<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated Statements of Comprehensive Income/(Loss)</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,129 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">115 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">235 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,979 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,253 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,156 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,409 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,382 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,656 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">115 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">235 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,388 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,673)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(17,504)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,225)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(27,797)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(57,199)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(65,444)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(40,667)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,116)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,244)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(110,471)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total Operating expenses</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(74,118)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(58,171)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,341)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(29,041)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(167,671)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investment held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">179,316 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">179,316 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Realized loss on sale of investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(20,925)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(20,925)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">70 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,523 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,593 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total other income/(expense)</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">70 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">159,914 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">159,983 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(16)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,528 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(784)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,679)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,050 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associate accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(73,703)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(73,703)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) before taxes </span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(64,753)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42,917)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,010)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">55,727 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(58,953)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(Loss)/income before taxes pre IFRS 9 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(60,368)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(44,335)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,248)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">63,628 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(47,323)</span></td><td style="border-right:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income/(costs) – IFRS 9 fair value accounting</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,322 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(716)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,606 </span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,066)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,224)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(32)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,628)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(13,950)</span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation of tangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,319)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,506)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(12)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,510)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,347)</span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of ROU assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,174)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,764)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,938)</span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of intangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2)</span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,756)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,756)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(64,753)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42,917)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,010)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51,971 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(62,709)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(64,753)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(42,917)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,010)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51,971 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(62,709)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) attributable to:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Owners of the Company</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(64,657)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,283)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,574)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">51,956 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(60,558)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-controlling interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(96)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,634)</span></td><td style="border-bottom:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(436)</span></td><td style="border-bottom:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15 </span></td><td style="border-bottom:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,151)</span></td><td style="border-bottom:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="15" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">December 31, 2021 $000s</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated Statements of Financial Position:</span></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #001544;padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total assets</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">125,726 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">64,508 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,765 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">754,007 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">946,006 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="padding-left:5.67pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total liabilities</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">228,789 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">209,212 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19,645 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(95,787)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">361,859 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net (liabilities)/assets</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(103,063)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(144,704)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(17,880)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">849,794 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">584,147 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Parent Company and Other Includes eliminations of intercompany liabilities between the Parent Company and the reportable segments in the amount of $233.3 million.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The proportion of net assets shown above that is attributable to non-controlling interest is disclosed in Note 18. </span></div><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="15" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Non-Controlled Founded<br/>Entities<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Parent Company &amp;<br/>Other<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Consolidated<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consolidated Statements of Comprehensive Loss</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contract revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,297 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">896 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">93 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,054 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,341 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,563 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,864 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,427 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,860 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,760 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">93 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,054 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,768 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative expenses</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,482)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,752)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,939)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(32,267)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(49,440)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45,346)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(33,152)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,128)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(234)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(81,859)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total operating expense</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(48,828)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(43,904)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,067)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(32,500)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(131,299)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense):</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on investment held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">232,674 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">232,674 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Realized loss on sale of investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(54,976)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(54,976)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on disposal of assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(30)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 12.34pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">965 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,065 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other income/(expense)</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">85 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">178,662 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">178,732 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net finance income/(costs)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,352)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(852)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(930)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,115)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net income/(loss) of associate accounted for using the equity method</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(34,117)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(34,117)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) before taxes</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,964)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45,410)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,826)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">113,170 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,969 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(Loss)/income before taxes pre IAS 39 fair value accounting, finance costs – subsidiary preferred shares, share-based payment expense, depreciation of tangible assets and amortization of intangible assets</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(38,349)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(36,736)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,866)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">121,644 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">40,694 </span></td><td style="border-right:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income/(costs) – IFRS 9 fair value accounting</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,492)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(859)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,351)</span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,762)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,469)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(83)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,405)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,718)</span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation of tangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(854)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,528)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(17)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,547)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,945)</span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of ROU assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,186)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,523)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,709)</span></td><td style="border-right:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-left:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization of intangible assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1)</span></td><td style="border-right:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Taxation</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(14,400)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(14,401)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,964)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45,411)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,826)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">98,769 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,568 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">469 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">469 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,964)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(45,411)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,826)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99,238 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,037 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) attributable to:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Owners of the Company</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(41,773)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(44,506)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,519)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">99,253 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,454 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 6.67pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-controlling interests</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(191)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(905)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(306)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,417)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table>
CY2022Q4 ptv Liabilities Intercompany Eliminations Between Parent Company And Reportable Segments
LiabilitiesIntercompanyEliminationsBetweenParentCompanyAndReportableSegments
255500000 usd
CY2021Q4 ptv Liabilities Intercompany Eliminations Between Parent Company And Reportable Segments
LiabilitiesIntercompanyEliminationsBetweenParentCompanyAndReportableSegments
233300000 usd
CY2022 ifrs-full Disclosure Of Finance Cost Explanatory
DisclosureOfFinanceCostExplanatory
Finance Cost, net <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table shows the breakdown of finance income and costs:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:63.330%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance income</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest income from financial assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,799</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">214 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,183 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance income</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,799</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">214 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,183 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance costs</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Contractual interest expense on notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(212)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,031)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(96)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest expense on other borrowings</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,759)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,502)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(496)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest expense on lease liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,982)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,181)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,354)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) on foreign currency exchange</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(56)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance cost – contractual</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,939)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,771)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,946)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) from change in fair value of warrant liability</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,740</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,419 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(117)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) from change in fair value of preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">130,825</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,362 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,234)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(loss) from change in fair value of convertible debt</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(502)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(175)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total finance income/(costs) – fair value accounting</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">137,063</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,606 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,351)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Finance income/(costs), net</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">138,924</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,050 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,115)</span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>
CY2020Q4 ifrs-full Noncurrent Financial Assets At Fair Value Through Profit Or Loss
NoncurrentFinancialAssetsAtFairValueThroughProfitOrLoss
553167000 usd
CY2021 ifrs-full Losses On Disposals Of Investments
LossesOnDisposalsOfInvestments
20925000 usd
CY2021 ifrs-full Increase Decrease In Fair Value Measurement Assets
IncreaseDecreaseInFairValueMeasurementAssets
179271000 usd
CY2021Q4 ptv Financial Assets At Fair Value Through Profit Or Loss Before Allocation To Long Term Interest
FinancialAssetsAtFairValueThroughProfitOrLossBeforeAllocationToLongTermInterest
493888000 usd
CY2022 ptv Financial Investments Gain Loss Recognised Through Profit Loss When Control Of Subsidiary Is Lost
FinancialInvestmentsGainLossRecognisedThroughProfitLossWhenControlOfSubsidiaryIsLost
11168000 usd
CY2022 ifrs-full Increase Decrease In Fair Value Measurement Assets
IncreaseDecreaseInFairValueMeasurementAssets
-32060000 usd
CY2022Q4 ifrs-full Noncurrent Financial Assets At Fair Value Through Profit Or Loss
NoncurrentFinancialAssetsAtFairValueThroughProfitOrLoss
251892000 usd
CY2022Q4 ptv Share Of Associate Loss Allocated To Long Term Interest
ShareOfAssociateLossAllocatedToLongTermInterest
-96700000 usd
CY2022Q4 ptv Share Of Associate Loss Allocated To Long Term Interest
ShareOfAssociateLossAllocatedToLongTermInterest
-96700000 usd
CY2021 ifrs-full Losses On Disposals Of Investments
LossesOnDisposalsOfInvestments
20900000 usd
CY2022 ifrs-full Gains Losses Recognised When Control In Subsidiary Is Lost
GainsLossesRecognisedWhenControlInSubsidiaryIsLost
27300000 usd
CY2022 ifrs-full Disclosure Of Significant Investments In Associates Explanatory
DisclosureOfSignificantInvestmentsInAssociatesExplanatory
Investments in Associates<div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis was founded by PureTech and raised funding through preferred shares financings as well as issuances of warrants and loans. As of July 1, 2019, Gelesis was deconsolidated from the Group’s financial statements. While the Group no longer controls Gelesis, it was concluded that PureTech still has significant influence over Gelesis and as such Gelesis is accounted for as an associate under IAS 28 in the consolidated financial statements.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Upon the date of deconsolidation, PureTech held preferred shares and common shares of Gelesis and warrants issued by Gelesis to PureTech. PureTech’s investment in common shares of Gelesis is subject to equity method accounting. See table below for the Group's share in the profits and losses of Gelesis for the periods presented.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The preferred shares and warrants held by PureTech fell under the guidance of IFRS 9 and were treated as financial assets held at fair value, where changes to the fair value of the preferred shares and warrants were recorded through the Consolidated Statement of Comprehensive Income/(Loss). See Note 5 above.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Years ended December 31, 2020 and 2021</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the years ended December 31, 2021 and 2020, the Group recorded its share in the losses of Gelesis. In 2020 the Group's investment in associates accounted for under the equity method was reduced to zero. Since the Group had investments in Gelesis warrants and preferred shares that were deemed to be Long-term interests, the Company continued recognizing its share in Gelesis losses while applying such losses to its preferred share and warrant investment in Gelesis accounted for as an investment held at fair value. In 2021, the total investment in Gelesis, including the Long-term interests, was reduced to zero. Since the Group did not incur legal or constructive obligations or made payments on behalf of Gelesis, the Group discontinued recognizing equity method losses in 2021. As of December 31, 2021, unrecognized equity method losses amounted to $38.1 million, which included $0.7 million of unrecognized other comprehensive loss.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During 2021, due to exercise of stock options into common shares in Gelesis the Group's equity interest in Gelesis was reduced from 47.9 percent at December 31, 2020 to 42.0 percent as of December 31, 2021. The gain resulting from the issuance of shares to third parties and the resulting reduction in the Group's share in the accumulated deficit of Gelesis under the equity method was fully offset by the unrecognized equity method losses.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Backstop agreement – 2022 and 2021</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On December 30, 2021, PureTech signed a Backstop agreement with Capstar according to which PureTech had committed to acquire Capstar class A common shares immediately prior to the closing of the business combination between Gelesis and Capstar, in case subsequent to the redemptions of Capstar shares being completed, the Available Funds, as defined in the agreement, were less than$15.0 million. PureTech had committed to acquire two thirds of the necessary shares at $10 per share so that the Available Funds increase to $15.0 million. According to the Backstop agreement, in case PureTech were required to acquire any shares under the agreement, PureTech would receive an additional 1,322,500 class A common shares of Capstar (immediately prior to the closing of the business combination) at no additional consideration.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company determined that such agreement meets the definition of a derivative under IFRS 9 and as such should be recorded at fair value with changes in fair value recorded through profit and loss. The derivative was initially recorded at fair value adjusted to defer the day 1 gain equal to the difference between the fair value of $11.2 million and transaction price of zero on the effective date and as such was initially recorded at zero. The deferred gain was amortized to Other income (expense) in the Consolidated Statement of Income (loss) over the period from the effective date until settlement date, January 13, 2022. During the years ended December 31, 2022 and 2021, the Group recognized income of $10.4 million and $0.8 million, respectively for the amortization of the deferred gain. During the year ended December 31, 2022 the Group recognized a loss of $2.8 million in respect of the decrease in the fair value of the derivative until date of settlement, resulting in a net gain of $7.6 million recorded during the year ended December 31, 2022 in respect of the Backstop agreement. The gain was recorded in the line item Other Income/(expense) in the Consolidated Statements of Comprehensive Income/(Loss). The fair value of the derivative on the date of settlement in the amount of $8.4 million represents an additional investment in Gelesis as part of the SPAC transaction described below.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On January 13, 2022, as part of the conclusion of the aforementioned Backstop agreement, the Group acquired 496,145 class A common shares of Capstar for $5.0 million and received an additional 1,322,500 common A shares of Capstar for no additional consideration.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2022</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Share exchange – Capstar</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On January 13, 2022, Gelesis completed its business combination with Capstar Special Purpose Acquisition Corp ("Capstar"). As part of the business combination, all shares in Gelesis, common and preferred, including the shares held by PureTech, were exchanged for common shares of the merged entity and unvested common shares that will vest upon the stock price of the new combined entity reaching certain target prices (hereinafter "Earn-out shares"). In addition, PureTech invested $15.0 million in the class A common shares of Capstar as part of the PIPE transaction that took place immediately prior to the closing of the business combination and an additional $5.0 million, as part of the Backstop agreement described above. Pursuant to the business combination, Gelesis became a wholly-owned subsidiary of Capstar and Capstar changed its name to Gelesis Holdings, Inc., which began trading on the New York Stock Exchange under the ticker symbol "GLS" on January 14, 2022. Following the closing of the business combination, the PIPE transaction, the settlement of the aforementioned Backstop agreement with Capstar, and the exchange of all preferred shares in Gelesis to common shares in the new combined entity, PureTech holds 16,727,582 common shares of Gelesis Holdings Inc., which was equal to approximately 23.2% of Gelesis Holdings Inc's outstanding common shares at the time of the exchange. Due to PureTech's significant equity holding and voting interest in Gelesis, PureTech continues to maintain significant influence in Gelesis and as such continues to account for its Gelesis equity investment under the equity method.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis was deemed to be the acquirer in Gelesis Holdings Inc. and the financial assets and financial liabilities in Capstar were deemed to be acquired by Gelesis in consideration for the shares held by Capstar legacy shareholders. As such, the Group did </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">not revalue the retained investment in Gelesis but rather treated the exchange as a dilution of its equity interest in Gelesis from 42.0 percent as of December 31, 2021 to 22.8 percent as of January 13, 2022 (including warrants that provide its holders access to returns associated with equity holders). After considering the aforementioned additional investments, the exchange of the preferred stock, previously accounted for as an investment held at fair value, to common stock (and representing an additional equity investment in Gelesis – See Note 5), the Earn-out shares received in Gelesis (see Note 5) and the offset of previously unrecognized equity method losses, the net gain recorded on the dilution of interest amounted to $28.3 million.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Following Gelesis’s decline in its market price in 2022 and its lack of liquidity, the Group recorded an impairment loss of $8.4 million as of December 31, 2022 in respect of its investment in Gelesis. The recoverable amount of the investment in Gelesis was $4.9 million as of December 31, 2022, which was determined based on fair value less costs to sell (costs to sell were estimated to be insignificant). Fair value was determined based on level 1 of the fair value hierarchy as Gelesis shares were traded on an active market as of December 31, 2022.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The impairment loss was presented separately in the Consolidated Statement of Comprehensive Income/ (loss) for the year ended December 31, 2022 in the line item Impairment of investment in associate.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On May 25, 2022, Sonde completed a Series B Preferred Share financing. As a result of the aforementioned financing, the Group's voting interest was reduced below 50% and the Group lost its control over Sonde and as such ceased to consolidate Sonde on the date the round of financing was completed. See Note 5 above for further details. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Following deconsolidation, the Group has significant influence in Sonde through its voting interest in Sonde and its remaining representation on Sonde's Board of Directors. The Group's voting interest at date of deconsolidation and as of December 31, 2022 was 48.2% and 40.17%, respectively. The Group holds Preferred A-1, A-2 and B shares. The Preferred A-1 shares, in substance, have the same terms as common stock and as such provide their shareholders with access to returns associated with a residual equity ownership in Sonde. Consequently, the investment in Preferred A-1 shares is accounted for under the equity method. The Preferred A-2 and B shares, however, do not provide their shareholders with access to returns associated with a residual equity interest and as such are accounted for under IFRS 9, as investments held at fair value. See Note 5.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the Preferred A-1 shares on the date of deconsolidation amounted to $7.7 million, which is the initial value of the equity method investment in Sonde. When applying the equity method, the Group records its share of the losses in Sonde based on its equity interest in Sonde. Since only the common shares and Preferred A-1 shares in Sonde represent a residual equity interest and PureTech is the sole holder of the Preferred A-1 shares, the Group's share in Sonde's equity is 93.6%. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2022 the Company recorded $3.4 million of equity method losses in respect of Sonde.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the activity related to the investment in associates balance for the years ended December 31, 2022 and 2021.</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:87.043%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.757%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Investment in Associates</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000's</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">As of January 1, 2021</span></div></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of net loss in Gelesis - limited to net investment amount</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(73,703)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of losses recorded against Long Term Interests (LTIs)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">73,703 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">As of December 31, 2021 and January 1, 2022</span></div></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash investment in associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19,961 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additional investment as a result of backstop settlement (see above)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,424 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain on dilution of interest in associate (*)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,793 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment in Sonde - deconsolidation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,680 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share in net loss of associates</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(27,749)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reversal of equity method losses recorded against LTIs (due to decrease in LTI fair value)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,406)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share in other comprehensive loss of associates</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(166)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,390)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">As of December 31, 2022</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">9,147</span><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">*    Gain on dilution of interest was further increased due to the receipt of Gelesis earn out shares accounted for as investments held at fair value (see above).</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Summarized financial information</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the financial information of Gelesis as included in its own financial statements, adjusted for fair value adjustments at deconsolidation and differences in accounting policies. The table also reconciles the summarized financial information to the carrying amount of the Company’s interest in Gelesis. </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:63.330%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:0 1pt"/></tr><tr style="height:8pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of and for the year ended December 31,</span></td><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Percentage ownership interest</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">22.5</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">42.0 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-current assets</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">333,040</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">357,508 </span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">23,495</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">66,092 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-current liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(99,053)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(120,786)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(80,010)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(537,432)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non controlling interests and options issued to third parties</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(46,204)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(14,216)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net assets (deficit) attributable to shareholders of Gelesis Inc.</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">131,268</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(248,834)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Group's share of net assets (net deficit)</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">29,504</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(104,527)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Goodwill</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,858</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,211 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Impairment </span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(28,452)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(37,495)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity method losses recorded against Long-term Interests</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">96,709 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Unrecognized equity method losses (*)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">38,101 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Investment in associate</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,910</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/></tr><tr style="height:11pt"><td colspan="3" style="border-top:0.5pt solid #183964;padding:0 1pt"/><td colspan="3" rowspan="2" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:11pt"><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Revenue</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,767</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,185 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21,442 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Loss from continuing operations (100%)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(111,567)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(271,430)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(71,157)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive loss (100%)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(112,285)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(273,005)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(70,178)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Group's share in net losses - limited to net investment amount (**)</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(24,306)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(73,703)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(34,117)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Group's share of total comprehensive loss - limited to net investment amount</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(24,472)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(73,703)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(33,648)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">*    Unrecognized equity method losses includes unrecognized other comprehensive loss of $0.7 million for the year ended December 31, 2021.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">**    For the year ended December 31, 2022 includes $4.4 million reversal of equity method losses recorded against Long-Term Interest (LTI) due to the decrease in fair value of such LTI.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsequent to balance sheet date, on April 10, 2023, the NYSE commenced proceedings to delist the common stock of Gelesis from the NYSE due to Gelesis ceasing to meet certain conditions to trade on such stock exchange. Trading in Gelesis’s common stock was suspended immediately, and it was subsequently delisted from the NYSE. The common stock of Gelesis is currently available for trading in the over-the-counter (“OTC”) market under the symbol GLSH. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In addition, in April 2023 (subsequent to balance sheet date) PureTech submitted a non-binding proposal to acquire all of the outstanding equity of Gelesis. Negotiations related to the proposal and any potential deal remain ongoing and are subject to, among other things, approval of any definitive transaction by independent committees of the boards of both Gelesis and PureTech. </span></div>See note 16 for the note issued to the Group by Gelesis and see Note 26 for additional details, including information related to an additional note issued by Gelesis to the Group subsequent to balance sheet date.
CY2022 ifrs-full Impairment Loss Recognised In Profit Or Loss
ImpairmentLossRecognisedInProfitOrLoss
8400000 usd
CY2020Q4 ifrs-full Investments In Associates
InvestmentsInAssociates
0 usd
CY2021 ptv Share Of Associate Loss Recorded Against Long Term Interest
ShareOfAssociateLossRecordedAgainstLongTermInterest
73703000 usd
CY2021Q4 ifrs-full Investments In Associates
InvestmentsInAssociates
0 usd
CY2022 ifrs-full Purchase Of Interests In Associates
PurchaseOfInterestsInAssociates
19961000 usd
CY2022 ptv Spac Exchange Additional Investment In Associates
SPACExchangeAdditionalInvestmentInAssociates
8424000 usd
CY2022 ptv Gain Loss Recognized On Dilution Of Ownership Interest In Associate Without Earn Out Shares
GainLossRecognizedOnDilutionOfOwnershipInterestInAssociateWithoutEarnOutShares
13793000 usd
CY2022 ifrs-full Share Of Profit Loss Of Associates And Joint Ventures Accounted For Using Equity Method
ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod
-27749000 usd
CY2022 ptv Reversal Of Investment Loss In Associates Accounted For Using Equity Method
ReversalOfInvestmentLossInAssociatesAccountedForUsingEquityMethod
4406000 usd
CY2022 ifrs-full Impairment Loss Recognised In Profit Or Loss
ImpairmentLossRecognisedInProfitOrLoss
8390000 usd
CY2022Q4 ifrs-full Investments In Associates
InvestmentsInAssociates
9147000 usd
CY2022 ptv Reversal Of Investment Loss In Associates Accounted For Using Equity Method
ReversalOfInvestmentLossInAssociatesAccountedForUsingEquityMethod
4400000 usd
CY2022 ifrs-full General And Administrative Expense
GeneralAndAdministrativeExpense
60991000 usd
CY2021 ifrs-full General And Administrative Expense
GeneralAndAdministrativeExpense
57199000 usd
CY2020 ifrs-full General And Administrative Expense
GeneralAndAdministrativeExpense
49440000 usd
CY2022 ifrs-full Research And Development Expense
ResearchAndDevelopmentExpense
152433000 usd
CY2021 ifrs-full Research And Development Expense
ResearchAndDevelopmentExpense
110471000 usd
CY2020 ifrs-full Research And Development Expense
ResearchAndDevelopmentExpense
81859000 usd
CY2022 ifrs-full Operating Expense
OperatingExpense
213425000 usd
CY2021 ifrs-full Operating Expense
OperatingExpense
167671000 usd
CY2020 ifrs-full Operating Expense
OperatingExpense
131299000 usd
CY2022 ifrs-full Disclosure Of Information About Employees Explanatory
DisclosureOfInformationAboutEmployeesExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The average number of persons employed by the Group during the year, analyzed by category, was as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ending December 31,</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">57</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">52 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">43 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">144</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">119 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">95 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">201</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">171 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">138 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>
CY2022 ifrs-full Average Number Of Employees
AverageNumberOfEmployees
201
CY2021 ifrs-full Average Number Of Employees
AverageNumberOfEmployees
171
CY2020 ifrs-full Average Number Of Employees
AverageNumberOfEmployees
138
CY2022 ifrs-full Disclosure Of Other Operating Expense Explanatory
DisclosureOfOtherOperatingExpenseExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Detailed operating expenses were as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ending December 31,</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Salaries and wages</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">41,750</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">36,792 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">29,403 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Healthcare benefits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,908</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,563 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,866 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Payroll taxes</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,286</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,084 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,629 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,699</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,950 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,718 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total payroll costs</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">61,643</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">55,388 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">43,616 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.5pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other general and administrative expenses</span></td><td colspan="2" style="border-top:0.5pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,669</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.5pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30,761 </span></td><td style="border-top:0.5pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">26,497 </span></td><td style="border-top:0.5pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other research and development expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">116,113</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">81,521 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">61,186 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total other operating expenses</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">151,782</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">112,282 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">87,683 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total operating expenses</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">213,425</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">167,671 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">131,299 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>
CY2022 ifrs-full Wages And Salaries
WagesAndSalaries
41750000 usd
CY2021 ifrs-full Wages And Salaries
WagesAndSalaries
36792000 usd
CY2020 ifrs-full Wages And Salaries
WagesAndSalaries
29403000 usd
CY2022 ifrs-full Employee Benefits Expense
EmployeeBenefitsExpense
2908000 usd
CY2021 ifrs-full Employee Benefits Expense
EmployeeBenefitsExpense
2563000 usd
CY2020 ifrs-full Employee Benefits Expense
EmployeeBenefitsExpense
1866000 usd
CY2022 ptv Payroll Taxes
PayrollTaxes
2286000 usd
CY2021 ptv Payroll Taxes
PayrollTaxes
2084000 usd
CY2020 ptv Payroll Taxes
PayrollTaxes
1629000 usd
CY2022 ifrs-full Expense From Sharebased Payment Transactions With Employees
ExpenseFromSharebasedPaymentTransactionsWithEmployees
14699000 usd
CY2021 ifrs-full Expense From Sharebased Payment Transactions With Employees
ExpenseFromSharebasedPaymentTransactionsWithEmployees
13950000 usd
CY2020 ifrs-full Expense From Sharebased Payment Transactions With Employees
ExpenseFromSharebasedPaymentTransactionsWithEmployees
10718000 usd
CY2022 ptv Payroll Costs
PayrollCosts
61643000 usd
CY2021 ptv Payroll Costs
PayrollCosts
55388000 usd
CY2020 ptv Payroll Costs
PayrollCosts
43616000 usd
CY2022 ptv Other Selling General And Administrative Expense
OtherSellingGeneralAndAdministrativeExpense
35669000 usd
CY2021 ptv Other Selling General And Administrative Expense
OtherSellingGeneralAndAdministrativeExpense
30761000 usd
CY2020 ptv Other Selling General And Administrative Expense
OtherSellingGeneralAndAdministrativeExpense
26497000 usd
CY2022 ptv Other Research And Development Expense
OtherResearchAndDevelopmentExpense
116113000 usd
CY2021 ptv Other Research And Development Expense
OtherResearchAndDevelopmentExpense
81521000 usd
CY2020 ptv Other Research And Development Expense
OtherResearchAndDevelopmentExpense
61186000 usd
CY2022 ifrs-full Miscellaneous Other Operating Expense
MiscellaneousOtherOperatingExpense
151782000 usd
CY2021 ifrs-full Miscellaneous Other Operating Expense
MiscellaneousOtherOperatingExpense
112282000 usd
CY2020 ifrs-full Miscellaneous Other Operating Expense
MiscellaneousOtherOperatingExpense
87683000 usd
CY2022 ifrs-full Operating Expense
OperatingExpense
213425000 usd
CY2021 ifrs-full Operating Expense
OperatingExpense
167671000 usd
CY2020 ifrs-full Operating Expense
OperatingExpense
131299000 usd
CY2022 ifrs-full Disclosure Of Auditors Remuneration Explanatory
DisclosureOfAuditorsRemunerationExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Auditor's remuneration:</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ending December 31,</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Audit of these financial statements</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,716</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,183 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,145 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Audit of the financial statements of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">132</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">312 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">291 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Audit of the financial statements of associate**</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">814</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">571 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">350 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Audit-related assurance services*</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,157</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,868 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">490 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-audit related services</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">173 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,819</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,934 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,449 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">*    2021 – $468.2 thousand represents prepaid expenses related to an expected initial public offering of a subsidiary.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">**    Audit fees of $720.0 thousand, $500.0 thousand and $350.0 thousand in respect of financial statements of associates for the years ended December 31, 2022, 2021, and 2020 respectively, are not included within the consolidated financial statements. Fees related to the audit of the financial statements of associates have been disclosed in respect of 2022, 2021, and 2020 as these fees went towards supporting the audit opinion on the Group accounts. Such amounts were not previously disclosed in the 2020 financial statements.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Please refer to Note 8 for further disclosures related to share-based payments and Note 24 for management’s remuneration disclosures.</span></div>
CY2022 ifrs-full Auditors Remuneration For Audit Services
AuditorsRemunerationForAuditServices
1716000 usd
CY2021 ifrs-full Auditors Remuneration For Audit Services
AuditorsRemunerationForAuditServices
1183000 usd
CY2020 ifrs-full Auditors Remuneration For Audit Services
AuditorsRemunerationForAuditServices
1145000 usd
CY2022 ptv Audit Of Financial Statements Of Subsidiaries
AuditOfFinancialStatementsOfSubsidiaries
132000 usd
CY2021 ptv Audit Of Financial Statements Of Subsidiaries
AuditOfFinancialStatementsOfSubsidiaries
312000 usd
CY2020 ptv Audit Of Financial Statements Of Subsidiaries
AuditOfFinancialStatementsOfSubsidiaries
291000 usd
CY2022 ptv Audit Of Financial Statements Of Associates
AuditOfFinancialStatementsOfAssociates
814000 usd
CY2021 ptv Audit Of Financial Statements Of Associates
AuditOfFinancialStatementsOfAssociates
571000 usd
CY2020 ptv Audit Of Financial Statements Of Associates
AuditOfFinancialStatementsOfAssociates
350000 usd
CY2022 ptv Audit Related Assurance Services
AuditRelatedAssuranceServices
1157000 usd
CY2021 ptv Audit Related Assurance Services
AuditRelatedAssuranceServices
1868000 usd
CY2020 ptv Audit Related Assurance Services
AuditRelatedAssuranceServices
490000 usd
CY2022 ifrs-full Auditors Remuneration For Other Services
AuditorsRemunerationForOtherServices
0 usd
CY2021 ifrs-full Auditors Remuneration For Other Services
AuditorsRemunerationForOtherServices
0 usd
CY2020 ifrs-full Auditors Remuneration For Other Services
AuditorsRemunerationForOtherServices
173000 usd
CY2022 ifrs-full Auditors Remuneration
AuditorsRemuneration
3819000 usd
CY2021 ifrs-full Auditors Remuneration
AuditorsRemuneration
3934000 usd
CY2021 ptv Percentage Vote And Value Of Subsidiaries In The Group Consolidated State Tax Return
PercentageVoteAndValueOfSubsidiariesInTheGroupConsolidatedStateTaxReturn
0.50
CY2020 ifrs-full Auditors Remuneration
AuditorsRemuneration
2449000 usd
CY2021 ptv Prepaid Expenses For Expected Subsidiary Ipo Audit Related Assurance Services
PrepaidExpensesForExpectedSubsidiaryIPOAuditRelatedAssuranceServices
468200 usd
CY2022 ifrs-full Disclosure Of Sharebased Payment Arrangements Explanatory
DisclosureOfSharebasedPaymentArrangementsExplanatory
Share-based Payments<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payments includes stock options, restricted stock units (“RSUs”) and performance-based RSUs in which the expense is recognized based on the grant date fair value of these awards, except for performance based RSUs to executives that are treated as liability awards where expense is recognized based on reporting date fair value up until settlement date.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based Payment Expense</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group share-based payment expense for the years ended December 31, 2022, 2021 and 2020, were comprised of charges related to the PureTech Health plc incentive stock and stock option issuances and subsidiary stock plans.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table provides the classification of the Group’s consolidated share-based payment expense as reflected in the Consolidated Statement of Income/(Loss):</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:63.330%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Year ended December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">General and administrative</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,862</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,310 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,650 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Research and development</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,837</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,640 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,068 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,699</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,950 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,718 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Performance Share Plan</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In June 2015, the Group adopted the Performance Stock Plan (“PSP”). Under the PSP and subsequent amendments, awards of ordinary shares may be made to the Directors, senior managers and employees of, and other individuals providing services to the Company and its subsidiaries up to a maximum authorized amount of 10.0 percent of the total ordinary shares outstanding. The shares have various vesting terms over a period of service between two and four years, provided the recipient remains continuously engaged as a service provider.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The share-based awards granted under the PSP are generally equity settled (see cash settlements below) and expire 10 years from the grant date. As of December 31, 2022, the Company had issued share-based awards to purchase an aggregate of 24,889,462 shares under this plan.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSU activity for the years ended December 31, 2022, 2021 and 2020 is detailed as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Number of Shares/Units</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Avg Grant Date Fair Value (GBP) (*)</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at January 1, 2020</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,636,347</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.08</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,759,011 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.80 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,781,687)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.54 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(191,089)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.37 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2020 and January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,422,582</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.46</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,195,133 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.15 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,176,695)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.93 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(808,305)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.25 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,632,715</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.91</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,309,883 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.76 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(696,398)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.80 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,155,420)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.67 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2022</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,090,780</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.74</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">*    2021 – for liability awards based on fair value at reporting date.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span><br/></span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Each RSU entitles the holder to one ordinary share on vesting and the RSU awards are generally based on a cliff vesting schedule over a <span style="-sec-ix-hidden:id3VybDovL2RvY3MudjEvZG9jOjFhZmVlMDFjMjQ4MzQ3ZTNiZWU1ZTFlNTg5ZjBjZDVjL3NlYzoxYWZlZTAxYzI0ODM0N2UzYmVlNWUxZTU4OWYwY2Q1Y18yNDcvZnJhZzoxNWFiYjAwM2I3ZTg0ZGEwYjdiYjg1NGNhOTQ0MGRiNS90ZXh0cmVnaW9uOjE1YWJiMDAzYjdlODRkYTBiN2JiODU0Y2E5NDQwZGI1XzE2NDkyNjc0NjczOTY_9670e928-4eda-4d63-9738-6c2781619cb7">one</span> to <span style="-sec-ix-hidden:id3VybDovL2RvY3MudjEvZG9jOjFhZmVlMDFjMjQ4MzQ3ZTNiZWU1ZTFlNTg5ZjBjZDVjL3NlYzoxYWZlZTAxYzI0ODM0N2UzYmVlNWUxZTU4OWYwY2Q1Y18yNDcvZnJhZzoxNWFiYjAwM2I3ZTg0ZGEwYjdiYjg1NGNhOTQ0MGRiNS90ZXh0cmVnaW9uOjE1YWJiMDAzYjdlODRkYTBiN2JiODU0Y2E5NDQwZGI1XzE2NDkyNjc0Njc0MDY_b2c26493-8dd9-496f-be63-a25ef447ef74">three</span>-year requisite service period in which the Company recognizes compensation expense for the RSUs. Following vesting, each recipient will be required to make a payment of one pence per ordinary share on settlement of the RSUs. Vesting of the majority of the RSUs is subject to the satisfaction of performance and market conditions. The grant date fair value of market condition awards that were treated as equity settled awards were measured to reflect such conditions and there was no true-up for differences between expected and actual outcomes. For liability settled awards, see below.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company recognizes the estimated fair value of performance-based awards as share-based compensation expense over the performance period based upon its determination of whether it is probable that the performance targets will be achieved. The Company assesses the probability of achieving the performance targets at each reporting period. Cumulative adjustments, if any, are recorded to reflect subsequent changes in the estimated outcome of performance-related conditions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the market and performance-based awards is based on the Monte Carlo simulation analysis utilizing a Geometric Brownian Motion process with 100,000 simulations to value those shares. The model considers share price volatility, risk-free rate and other covariance of comparable public companies and other market data to predict distribution of relative share performance.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The performance and market conditions attached to the RSU awards are based on the achievement of total shareholder return (“TSR”), based on the achievement of absolute TSR targets, and to a lesser extent based on TSR as compared to the FTSE 250 Index, and the MSCI Europe Health Care Index. The remaining portion is based on the achievement of strategic targets. The RSU award performance criteria have changed over time as the criteria is continually evaluated by the Group’s Remuneration Committee.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:115%">In 2017, the Company granted certain executives RSUs that vested based on the service, market and performance conditions, as described above. The vesting of all RSUs was achieved by December 31, 2019 where all service, market and performance conditions were met. The remuneration committee of PureTech's Board of Directors approved the achievement of the vesting conditions as of December 31, 2019 and reached the decision during the year ended December 31, 2020 to cash settle the 2017 RSUs. The settlement value was determined based on the 3 day average closing price of the shares. The settlement value was $12.5 million </span><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:115%">(which after deducting tax withheld on behalf of recipients amounted to </span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:115%">$7.2 million</span><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:115%">)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:115%">. The settlement value did not exceed the fair value at settlement date and as such the cash settlement was treated as an equity transaction in the financial statements for the year ended December 31, 2020, whereby the full repurchase cash settlement amount was charged to equity in Other reserves.</span></div><div style="margin-bottom:5pt"><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Similarly in 2018, the Company granted certain executives RSUs that vested based on service, market and performance conditions, as described above. The vesting of all RSUs was achieved by </span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">December 31, 2020</span><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> where all service, market and performance conditions were met. In February 2021 the remuneration committee of PureTech's board of directors approved the achievement of the vesting conditions as of </span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">December 31, 2020 </span><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">and on May 28, 2021 reached the decision to cash settle RSUs to certain employees while others were issued shares. The settlement value was determined based on the three day average closing price of the shares. The settlement va</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">lue was $10.7 million (which </span><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">after deducting tax withheld on behalf of recipients amounted to $6.4 million). The settlement value did not exceed the fair value at settlement date and as such the cash settlement was treated as an equity transaction, whereby the full repurchase cash settlement amount was charged to equity in Other reserves in the financial statements as of and for the </span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">year ended December 31, 2021.</span></div><div style="margin-bottom:5pt"><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Following the different cash settlements, the Company concluded that although the remaining RSUs are to be settled by shares according to their respective agreements, and any cash settlement is at the Company's discretion, due to past practice of cash settlement to multiple employees, some for multiple years, these RSUs to the company executives should be treated as liability awards and as such adjusted to fair value at every reporting date with changes in fair value recorded in earnings as stock based compensation expense.</span></div><div style="margin-bottom:5pt"><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Consequently, the Company reclassified during the year ended December 31, 2021 $1.9 million from equity to other non-current liabilities and $4.8 million from equity to other payables equal to the fair value of the awards at the date of reclassification. The Company treated the excess of the fair value at the reclassification date over the grant date fair value of the RSUs (for the portion of the vesting period that has already elapsed) in the amount of $2.9 million as an equity transaction. Therefore the full amount of the liability at reclassification was recorded as a charge to equity. The changes in fair value of the liability from reclassification date to balance sheet date or settlement date are recorded as stock-based compensation expense in the Consolidated Statement of Comprehensive Income (loss). </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company incurred share-based payment expenses for performance, market and service based RSUs of $1.6 million (including $1.1 million expense in respect of RSU liability awards), $1.5 million (including $0.6 million expense in respect of RSU liability awards), and $5.7 million for the years ended December 31, 2022, 2021 and 2020, respectively. The decrease in the share based compensation expense in respect of the RSUs for the year ended December 31, 2021, as compared to the year ended December 31, 2020 is due to reduction in the fair value of the liability awards as compared to their value at the date the awards were reclassified from equity awards to liability awards, as well as forfeitures of certain awards due to unexpected terminations of RSU holders. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2022, the carrying amount of the RSU liability awards was $5.9 million, $1.8 million current; $4.1 million non current, out of which $1.8 million related to awards that have met all their performance and market conditions.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Stock Options</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Stock option activity for the years ended December 31, 2022, 2021 and 2020, is detailed as follows:</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:51.621%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Number of Options</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average Exercise Price (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average of<br/>remaining contractual<br/>term (in years)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average Stock Price at Exercise (GBP)</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at January 1, 2020</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,472,827</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.16</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.55</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,076,982 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.14 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(514,410)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.52 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.88</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited and expired</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,119,313)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.88 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.19pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2020 and January 1, 2021</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,447,405</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.98</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7.46</span></td><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at December 31, 2020 and January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,916,086</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.81</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.38</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,424,000 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.34 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,238,187)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.70 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.63</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited and expired</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(687,781)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.53 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.19pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,773,873</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.42</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.50</span></td><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,414,118</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.58</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.29</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,881,000 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.04 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(577,022)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.50 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.43</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited and expired</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,924,215)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.89 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2022</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,185,216</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.03</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.21</span></td><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at December 31, 2022</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">17,793,881</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.31</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.03</span></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the stock options awarded by the Company was estimated at the grant date using the Black-Scholes option valuation model, considering the terms and conditions upon which options were granted, with the following weighted-average assumptions:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">At December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected volatility</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">41.70</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41.05 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41.25 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected terms (in years)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.11</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.16</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.11</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Risk-free interest rate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.13</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.06 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.53 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected dividend yield</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant date fair value</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$1.15</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$1.87 </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$1.72 </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company incurred share-based payment expense for the stock options of $8.4 million, $6.2 million and $2.1 million for the years ended December 31, 2022, 2021 and 2020, respectively. The increase in expense for the year ended December 31, 2022, as compared to the year ended December 31, 2021, is due to the new grants granted in 2022. The increase in expense for the year ended December 31, 2021, as compared to the year ended December 31, 2020, is due to new grants granted in 2021.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For shares outstanding as of December 31, 2022, the range of exercise prices is detailed as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Range of Exercise Prices (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Options<br/>Outstanding</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd<br/>Average<br/>Exercise<br/>Price (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average of<br/>remaining contractual<br/>term (in years)</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.01</span></div></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">439,490 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.76</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.00 to 2.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,276,391 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.58 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7.00</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.00 to 3.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,375,750 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.26 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.92</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.00 to 4.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,702,250 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.34 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.40</span></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">17,793,881</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.31</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.03</span></td></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary Plans</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain subsidiaries of the Group have adopted stock option plans. A summary of stock option activity by number of shares in these subsidiaries is presented in the following table:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:14.968%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.692%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.760%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Outstanding as of January 1, 2022</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Granted During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Exercised During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Expired During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Forfeited During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Deconsolidation During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Outstanding as of December 31, 2022</span></div></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">349,500</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">45,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(50,000)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">344,500</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,686,120</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">90,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,776,120</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,049,004</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,049,004)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,991,637</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">490,506</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(400,000)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(65,235)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(192,332)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,824,576</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:14.812%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.848%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.760%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding as of January 1, 2021</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Granted During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Exercised During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Expired During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Forfeited During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Deconsolidation During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding as of December 31, 2021</span></div></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,888,168 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">197,398 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,373,750)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(506,260)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,205,556)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">962,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(525,000)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(87,500)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">349,500 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,309,040 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,383,080 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,000)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,686,120 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,192,834 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(51,507)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(92,323)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,049,004 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,741,888 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">451,532 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(52,938)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(76,491)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(72,354)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,991,637 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:14.812%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.848%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.760%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding as of January 1, 2020</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Granted During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Exercised During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Expired During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Forfeited During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Deconsolidation During the Year</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding as of December 31, 2020</span></div></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,698,244 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">189,924 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,888,168 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">972,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,000)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">962,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,309,040 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,309,040 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,829,004 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">363,830 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,192,834 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,450,100 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">493,951 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(813)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(201,350)</span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,741,888 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span><br/></span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span><br/></span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The weighted-average exercise prices and remaining contractual life for the options outstanding as of December 31, 2022, were as follows:</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Outstanding at December 31, 2022</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of options</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average exercise price</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average contractual life outstanding</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">344,500</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.91</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.92</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,776,120</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.41</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.38</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,824,576</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15.89</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.88</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The weighted average exercise prices for the options granted for the years ended December 31, 2022, 2021 and 2020, were as follows:</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the years ended December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$</span></div></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Alivio</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.47 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.02</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.86</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.86 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.18 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14.94</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19.69 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19.59 </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The weighted average exercise prices for options forfeited during the year ended December 31, 2022, were as follows: </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Forfeited during the year ended December 31, 2022</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of options</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average exercise price</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">192,332</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">19.64</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The weighted average exercise prices for options exercised during the year ended December 31, 2022, were as follows:</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Exercised during the year ended December 31, 2022</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of options</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average exercise price<br/>$</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">400,000</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.02</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The weighted average exercise prices for options exercisable as of December 31, 2022, were as follows:</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:46.096%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Exercisable at December 31, 2022</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of Options</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Weighted-average exercise price</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Exercise Price Range<br/>$</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">344,500</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.91</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.02-2.36</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Follica</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,776,120</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.41</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.03-1.86</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta</span></td><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,824,576</span></td><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15.89</span></td><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.02-21.35</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Significant Subsidiary Plans</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Vedanta 2020 Stock Incentive Plan</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On June 2, 2020, the Company’s Board of Directors approved the 2020 Stock Incentive Plan, or 2020 Plan, which replaced the 2010 Stock Incentive Plan, or 2010 Plan, which was set to expire in December 2020. All authorized and issued shares under the 2010 Plan were transferred to the 2020 Plan. The 2020 Plan provides for the grant of incentive stock options, nonqualified stock options, and restricted stock to employees, directors, and nonemployees of the Company up to an aggregate of 2,145,867 shares of the Company's common stock. In March 2021, the Company’s Board of Directors approved an increase in </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">the authorized shares of 151,188 for a total of 2,297,055. In July 2021, the Company’s Board of Directors approved an increase in the authorized shares of 500,000 for a total of 2,797,055. Under the 2020 Plan, 914,331 shares remained available for issuance as of December 31, 2022.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The options granted under the 2020 Plan are equity settled and expire 10 years from the grant date. Typically, the awards vest in four years but vesting conditions can vary based on the discretion of Vedanta’s Board of Directors.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Options granted under the 2020 Plan are exercisable at a price per share not less than the fair market value of the underlying ordinary shares on the date of grant. The estimated fair value of options, including the effect of estimated forfeitures, is recognized over the options’ vesting period.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the stock option grants has been estimated at the date of grant using the Black-Scholes option pricing model with the following range of assumptions:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:46.096%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Assumption/Input</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected award life (in years)</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.00-8.33</span></div></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.00-7.11</span></div></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.00-10.00</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected award price volatility</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">88.22%-89.68%</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">88.05%-88.59%</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">89.24%-95.46%</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Risk free interest rate</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.67%-3.13%</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.96%-1.32%</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.32%-0.87%</span></div></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected dividend yield</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">—</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant date fair value</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$10.51-$15.14</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$13.84-$16.23</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$13.09-$16.54</span></div></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share price at grant date</span></td><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$14.00-$18.84</span></div></td><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$19.00-$21.35</span></div></td><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$19.59</span></div></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta incurred share-based compensation expense of $4.3 million, $5.4 million and $2.4 million for the years ended December 31, 2022, 2021 and 2020, respectively.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other Plans</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The stock compensation expense under plans at other subsidiaries of the Group not including Vedanta amounted to</span><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$0.4 million, $0.8 million and $0.4 million for the years ended December 31, 2022, 2021 and 2020, respectively.</span></div>
CY2022 ifrs-full Expense From Sharebased Payment Transactions With Employees
ExpenseFromSharebasedPaymentTransactionsWithEmployees
14699000 usd
CY2021 ifrs-full Expense From Sharebased Payment Transactions With Employees
ExpenseFromSharebasedPaymentTransactionsWithEmployees
13950000 usd
CY2020 ifrs-full Expense From Sharebased Payment Transactions With Employees
ExpenseFromSharebasedPaymentTransactionsWithEmployees
10718000 usd
CY2022 ifrs-full Disclosure Of Number And Weighted Average Exercise Prices Of Other Equity Instruments Explanatory
DisclosureOfNumberAndWeightedAverageExercisePricesOfOtherEquityInstrumentsExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSU activity for the years ended December 31, 2022, 2021 and 2020 is detailed as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Number of Shares/Units</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Avg Grant Date Fair Value (GBP) (*)</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at January 1, 2020</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,636,347</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.08</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,759,011 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.80 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,781,687)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.54 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(191,089)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.37 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2020 and January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,422,582</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.46</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,195,133 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.15 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,176,695)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.93 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(808,305)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.25 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,632,715</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.91</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">RSUs Granted in Period</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,309,883 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.76 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vested</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(696,398)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.80 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,155,420)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.67 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding (Non-vested) at December 31, 2022</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,090,780</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.74</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">*    2021 – for liability awards based on fair value at reporting date.</span></div>
CY2022 ptv Share Based Compensation Arrangement By Share Based Payment Award Number Of Common Shares Redeemed Per Restricted Share Unit
ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfCommonSharesRedeemedPerRestrictedShareUnit
1 shares
CY2022 ifrs-full Disclosure Of Number And Weighted Average Exercise Prices Of Share Options Explanatory
DisclosureOfNumberAndWeightedAverageExercisePricesOfShareOptionsExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Stock option activity for the years ended December 31, 2022, 2021 and 2020, is detailed as follows:</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:51.621%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Number of Options</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average Exercise Price (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average of<br/>remaining contractual<br/>term (in years)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average Stock Price at Exercise (GBP)</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at January 1, 2020</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,472,827</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.16</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.55</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,076,982 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.14 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(514,410)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.52 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.88</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited and expired</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,119,313)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.88 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.19pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2020 and January 1, 2021</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,447,405</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.98</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7.46</span></td><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at December 31, 2020 and January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,916,086</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.81</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.38</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,424,000 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.34 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,238,187)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.70 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.63</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited and expired</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(687,781)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.53 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.19pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,773,873</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1.42</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.50</span></td><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,414,118</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.58</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.29</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Granted</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,881,000 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.04 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exercised</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(577,022)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.50 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.43</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Forfeited and expired</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,924,215)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.89 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Options Exercisable at December 31, 2022</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,185,216</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.03</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.21</span></td><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Outstanding at December 31, 2022</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">17,793,881</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.31</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.03</span></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"/></tr></table></div>
CY2019Q4 ifrs-full Number Of Outstanding Share Options
NumberOfOutstandingShareOptions
8472827 shares
CY2019Q4 ifrs-full Weighted Average Exercise Price Of Share Options Outstanding In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsOutstandingInSharebasedPaymentArrangement2019
1.16
CY2019 ifrs-full Weighted Average Remaining Contractual Life Of Outstanding Share Options2019
WeightedAverageRemainingContractualLifeOfOutstandingShareOptions2019
P8Y6M18D
CY2020 ifrs-full Number Of Share Options Granted In Sharebased Payment Arrangement
NumberOfShareOptionsGrantedInSharebasedPaymentArrangement
4076982 shares
CY2020 ifrs-full Weighted Average Exercise Price Of Share Options Granted In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsGrantedInSharebasedPaymentArrangement2019
3.14
CY2020 ifrs-full Number Of Share Options Exercised In Sharebased Payment Arrangement
NumberOfShareOptionsExercisedInSharebasedPaymentArrangement
514410 shares
CY2020 ifrs-full Weighted Average Exercise Price Of Share Options Exercised In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsExercisedInSharebasedPaymentArrangement2019
1.52
CY2020 ptv Weighted Average Stock Price Of Share Options Exercised In Share Based Payment Arrangement
WeightedAverageStockPriceOfShareOptionsExercisedInShareBasedPaymentArrangement
2.88
CY2020 ptv Number Of Share Options Forfeited And Expired In Share Based Payment Arrangement
NumberOfShareOptionsForfeitedAndExpiredInShareBasedPaymentArrangement
1119313 shares
CY2020 ptv Weighted Average Exercise Price Of Share Options Forfeited And Expired In Share Based Payment Arrangement
WeightedAverageExercisePriceOfShareOptionsForfeitedAndExpiredInShareBasedPaymentArrangement
1.88
CY2020Q4 ifrs-full Number Of Share Options Exercisable In Sharebased Payment Arrangement
NumberOfShareOptionsExercisableInSharebasedPaymentArrangement
5447405 shares
CY2020Q4 ifrs-full Weighted Average Exercise Price Of Share Options Exercisable In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsExercisableInSharebasedPaymentArrangement2019
0.98
CY2020 ptv Weighted Average Remaining Contractual Life Of Options Excisable
WeightedAverageRemainingContractualLifeOfOptionsExcisable
P7Y5M15D
CY2020Q4 ifrs-full Number Of Outstanding Share Options
NumberOfOutstandingShareOptions
10916086 shares
CY2020Q4 ifrs-full Weighted Average Exercise Price Of Share Options Outstanding In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsOutstandingInSharebasedPaymentArrangement2019
1.81
CY2020 ifrs-full Weighted Average Remaining Contractual Life Of Outstanding Share Options2019
WeightedAverageRemainingContractualLifeOfOutstandingShareOptions2019
P8Y4M17D
CY2021 ifrs-full Number Of Share Options Granted In Sharebased Payment Arrangement
NumberOfShareOptionsGrantedInSharebasedPaymentArrangement
5424000 shares
CY2021 ifrs-full Weighted Average Exercise Price Of Share Options Granted In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsGrantedInSharebasedPaymentArrangement2019
3.34
CY2021 ifrs-full Number Of Share Options Exercised In Sharebased Payment Arrangement
NumberOfShareOptionsExercisedInSharebasedPaymentArrangement
2238187 shares
CY2021 ifrs-full Weighted Average Exercise Price Of Share Options Exercised In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsExercisedInSharebasedPaymentArrangement2019
0.70
CY2021 ptv Weighted Average Stock Price Of Share Options Exercised In Share Based Payment Arrangement
WeightedAverageStockPriceOfShareOptionsExercisedInShareBasedPaymentArrangement
3.63
CY2021 ptv Number Of Share Options Forfeited And Expired In Share Based Payment Arrangement
NumberOfShareOptionsForfeitedAndExpiredInShareBasedPaymentArrangement
687781 shares
CY2021 ptv Weighted Average Exercise Price Of Share Options Forfeited And Expired In Share Based Payment Arrangement
WeightedAverageExercisePriceOfShareOptionsForfeitedAndExpiredInShareBasedPaymentArrangement
2.53
CY2021Q4 ifrs-full Number Of Share Options Exercisable In Sharebased Payment Arrangement
NumberOfShareOptionsExercisableInSharebasedPaymentArrangement
4773873 shares
CY2021Q4 ifrs-full Weighted Average Exercise Price Of Share Options Exercisable In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsExercisableInSharebasedPaymentArrangement2019
1.42
CY2021 ptv Weighted Average Remaining Contractual Life Of Options Excisable
WeightedAverageRemainingContractualLifeOfOptionsExcisable
P6Y6M
CY2021Q4 ifrs-full Number Of Outstanding Share Options
NumberOfOutstandingShareOptions
13414118 shares
CY2021Q4 ifrs-full Weighted Average Exercise Price Of Share Options Outstanding In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsOutstandingInSharebasedPaymentArrangement2019
2.58
CY2021 ifrs-full Weighted Average Remaining Contractual Life Of Outstanding Share Options2019
WeightedAverageRemainingContractualLifeOfOutstandingShareOptions2019
P8Y3M14D
CY2022 ifrs-full Number Of Share Options Granted In Sharebased Payment Arrangement
NumberOfShareOptionsGrantedInSharebasedPaymentArrangement
8881000 shares
CY2022 ifrs-full Weighted Average Exercise Price Of Share Options Granted In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsGrantedInSharebasedPaymentArrangement2019
2.04
CY2022 ifrs-full Number Of Share Options Exercised In Sharebased Payment Arrangement
NumberOfShareOptionsExercisedInSharebasedPaymentArrangement
577022 shares
CY2022 ifrs-full Weighted Average Exercise Price Of Share Options Exercised In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsExercisedInSharebasedPaymentArrangement2019
0.50
CY2022 ptv Weighted Average Stock Price Of Share Options Exercised In Share Based Payment Arrangement
WeightedAverageStockPriceOfShareOptionsExercisedInShareBasedPaymentArrangement
2.43
CY2022 ptv Number Of Share Options Forfeited And Expired In Share Based Payment Arrangement
NumberOfShareOptionsForfeitedAndExpiredInShareBasedPaymentArrangement
3924215 shares
CY2022 ptv Weighted Average Exercise Price Of Share Options Forfeited And Expired In Share Based Payment Arrangement
WeightedAverageExercisePriceOfShareOptionsForfeitedAndExpiredInShareBasedPaymentArrangement
2.89
CY2022Q4 ifrs-full Number Of Share Options Exercisable In Sharebased Payment Arrangement
NumberOfShareOptionsExercisableInSharebasedPaymentArrangement
6185216 shares
CY2022Q4 ifrs-full Weighted Average Exercise Price Of Share Options Exercisable In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsExercisableInSharebasedPaymentArrangement2019
2.03
CY2022 ptv Weighted Average Remaining Contractual Life Of Options Excisable
WeightedAverageRemainingContractualLifeOfOptionsExcisable
P6Y2M15D
CY2022Q4 ifrs-full Number Of Outstanding Share Options
NumberOfOutstandingShareOptions
17793881 shares
CY2022Q4 ifrs-full Weighted Average Exercise Price Of Share Options Outstanding In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsOutstandingInSharebasedPaymentArrangement2019
2.31
CY2022 ifrs-full Weighted Average Remaining Contractual Life Of Outstanding Share Options2019
WeightedAverageRemainingContractualLifeOfOutstandingShareOptions2019
P8Y10D
CY2022 ifrs-full Disclosure Of Terms And Conditions Of Sharebased Payment Arrangement Explanatory
DisclosureOfTermsAndConditionsOfSharebasedPaymentArrangementExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the stock options awarded by the Company was estimated at the grant date using the Black-Scholes option valuation model, considering the terms and conditions upon which options were granted, with the following weighted-average assumptions:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">At December 31,</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected volatility</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">41.70</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41.05 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41.25 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected terms (in years)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6.11</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.16</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.11</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Risk-free interest rate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.13</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.06 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.53 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Expected dividend yield</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Grant date fair value</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">$1.15</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$1.87 </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">$1.72 </span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:left;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div>
CY2022 ifrs-full Description Of Expected Volatility Share Options Granted
DescriptionOfExpectedVolatilityShareOptionsGranted
0.4170
CY2021 ifrs-full Description Of Expected Volatility Share Options Granted
DescriptionOfExpectedVolatilityShareOptionsGranted
0.4105
CY2020 ifrs-full Description Of Expected Volatility Share Options Granted
DescriptionOfExpectedVolatilityShareOptionsGranted
0.4125
CY2022 ifrs-full Description Of Option Life Share Options Granted
DescriptionOfOptionLifeShareOptionsGranted
6.11 y
CY2021 ifrs-full Description Of Option Life Share Options Granted
DescriptionOfOptionLifeShareOptionsGranted
6.16 y
CY2020 ifrs-full Description Of Option Life Share Options Granted
DescriptionOfOptionLifeShareOptionsGranted
6.11 y
CY2022 ifrs-full Description Of Risk Free Interest Rate Share Options Granted
DescriptionOfRiskFreeInterestRateShareOptionsGranted
0.0213
CY2021 ifrs-full Description Of Risk Free Interest Rate Share Options Granted
DescriptionOfRiskFreeInterestRateShareOptionsGranted
0.0106
CY2020 ifrs-full Description Of Risk Free Interest Rate Share Options Granted
DescriptionOfRiskFreeInterestRateShareOptionsGranted
0.0053
CY2022 ifrs-full Expected Dividend Share Options Granted
ExpectedDividendShareOptionsGranted
0 usd
CY2021 ifrs-full Expected Dividend Share Options Granted
ExpectedDividendShareOptionsGranted
0 usd
CY2020 ifrs-full Expected Dividend Share Options Granted
ExpectedDividendShareOptionsGranted
0 usd
CY2022Q4 ifrs-full Weighted Average Fair Value At Measurement Date Share Options Granted
WeightedAverageFairValueAtMeasurementDateShareOptionsGranted
1.15 usd
CY2021Q4 ifrs-full Weighted Average Fair Value At Measurement Date Share Options Granted
WeightedAverageFairValueAtMeasurementDateShareOptionsGranted
1.87 usd
CY2020Q4 ifrs-full Weighted Average Fair Value At Measurement Date Share Options Granted
WeightedAverageFairValueAtMeasurementDateShareOptionsGranted
1.72 usd
CY2022 ifrs-full Disclosure Of Range Of Exercise Prices Of Outstanding Share Options Explanatory
DisclosureOfRangeOfExercisePricesOfOutstandingShareOptionsExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For shares outstanding as of December 31, 2022, the range of exercise prices is detailed as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Range of Exercise Prices (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Options<br/>Outstanding</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd<br/>Average<br/>Exercise<br/>Price (GBP)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Wtd Average of<br/>remaining contractual<br/>term (in years)</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.01</span></div></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">439,490 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6.76</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.00 to 2.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,276,391 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.58 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7.00</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.00 to 3.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,375,750 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.26 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.92</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.00 to 4.00</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,702,250 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.34 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.40</span></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">17,793,881</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2.31</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.03</span></td></tr></table></div>
CY2022Q4 ifrs-full Number Of Outstanding Share Options
NumberOfOutstandingShareOptions
17793881 shares
CY2022Q4 ifrs-full Weighted Average Exercise Price Of Share Options Outstanding In Sharebased Payment Arrangement2019
WeightedAverageExercisePriceOfShareOptionsOutstandingInSharebasedPaymentArrangement2019
2.31
CY2022 ifrs-full Weighted Average Remaining Contractual Life Of Outstanding Share Options2019
WeightedAverageRemainingContractualLifeOfOutstandingShareOptions2019
P8Y10D
CY2022 ptv Percentage Vote And Value Of Subsidiaries In The Group Consolidated State Tax Return
PercentageVoteAndValueOfSubsidiariesInTheGroupConsolidatedStateTaxReturn
0.50
CY2022 ifrs-full Interest Income For Financial Assets Not At Fair Value Through Profit Or Loss
InterestIncomeForFinancialAssetsNotAtFairValueThroughProfitOrLoss
5799000 usd
CY2021 ifrs-full Interest Income For Financial Assets Not At Fair Value Through Profit Or Loss
InterestIncomeForFinancialAssetsNotAtFairValueThroughProfitOrLoss
214000 usd
CY2020 ifrs-full Interest Income For Financial Assets Not At Fair Value Through Profit Or Loss
InterestIncomeForFinancialAssetsNotAtFairValueThroughProfitOrLoss
1183000 usd
CY2022 ifrs-full Finance Income
FinanceIncome
5799000 usd
CY2021 ifrs-full Finance Income
FinanceIncome
214000 usd
CY2020 ifrs-full Finance Income
FinanceIncome
1183000 usd
CY2022 ptv Contractual Interest Expense On Notes
ContractualInterestExpenseOnNotes
212000 usd
CY2021 ptv Contractual Interest Expense On Notes
ContractualInterestExpenseOnNotes
1031000 usd
CY2020 ptv Contractual Interest Expense On Notes
ContractualInterestExpenseOnNotes
96000 usd
CY2022 ifrs-full Interest Expense On Borrowings
InterestExpenseOnBorrowings
1759000 usd
CY2021 ifrs-full Interest Expense On Borrowings
InterestExpenseOnBorrowings
1502000 usd
CY2020 ifrs-full Interest Expense On Borrowings
InterestExpenseOnBorrowings
496000 usd
CY2022 ifrs-full Interest Expense On Lease Liabilities
InterestExpenseOnLeaseLiabilities
1982000 usd
CY2021 ifrs-full Interest Expense On Lease Liabilities
InterestExpenseOnLeaseLiabilities
2181000 usd
CY2020 ifrs-full Interest Expense On Lease Liabilities
InterestExpenseOnLeaseLiabilities
2354000 usd
CY2022 ptv Gain Loss On Foreign Currency Exchange In Finance Costs
GainLossOnForeignCurrencyExchangeInFinanceCosts
14000 usd
CY2021 ptv Gain Loss On Foreign Currency Exchange In Finance Costs
GainLossOnForeignCurrencyExchangeInFinanceCosts
-56000 usd
CY2020 ptv Gain Loss On Foreign Currency Exchange In Finance Costs
GainLossOnForeignCurrencyExchangeInFinanceCosts
0 usd
CY2022 ifrs-full Finance Costs
FinanceCosts
3939000 usd
CY2021 ifrs-full Finance Costs
FinanceCosts
4771000 usd
CY2020 ifrs-full Finance Costs
FinanceCosts
2946000 usd
CY2022 ptv Gain Loss From Change In Fair Value Of Warrant Liability
GainLossFromChangeInFairValueOfWarrantLiability
6740000 usd
CY2021 ptv Gain Loss From Change In Fair Value Of Warrant Liability
GainLossFromChangeInFairValueOfWarrantLiability
1419000 usd
CY2020 ptv Gain Loss From Change In Fair Value Of Warrant Liability
GainLossFromChangeInFairValueOfWarrantLiability
-117000 usd
CY2022 ptv Gain Loss From Change In Fair Value Of Preferred Shares
GainLossFromChangeInFairValueOfPreferredShares
130825000 usd
CY2021 ptv Gain Loss From Change In Fair Value Of Preferred Shares
GainLossFromChangeInFairValueOfPreferredShares
8362000 usd
CY2020 ptv Gain Loss From Change In Fair Value Of Preferred Shares
GainLossFromChangeInFairValueOfPreferredShares
-4234000 usd
CY2022 ptv Gain Loss From Change In Fair Value Of Convertible Debt
GainLossFromChangeInFairValueOfConvertibleDebt
-502000 usd
CY2021 ptv Gain Loss From Change In Fair Value Of Convertible Debt
GainLossFromChangeInFairValueOfConvertibleDebt
-175000 usd
CY2020 ptv Gain Loss From Change In Fair Value Of Convertible Debt
GainLossFromChangeInFairValueOfConvertibleDebt
0 usd
CY2022 ifrs-full Gains Losses Recognised In Profit Or Loss Fair Value Measurement Liabilities
GainsLossesRecognisedInProfitOrLossFairValueMeasurementLiabilities
137063000 usd
CY2021 ifrs-full Gains Losses Recognised In Profit Or Loss Fair Value Measurement Liabilities
GainsLossesRecognisedInProfitOrLossFairValueMeasurementLiabilities
9606000 usd
CY2020 ifrs-full Gains Losses Recognised In Profit Or Loss Fair Value Measurement Liabilities
GainsLossesRecognisedInProfitOrLossFairValueMeasurementLiabilities
-4351000 usd
CY2022 ifrs-full Finance Income Cost
FinanceIncomeCost
138924000 usd
CY2021 ifrs-full Finance Income Cost
FinanceIncomeCost
5050000 usd
CY2020 ifrs-full Finance Income Cost
FinanceIncomeCost
-6115000 usd
CY2022 ifrs-full Disclosure Of Earnings Per Share Explanatory
DisclosureOfEarningsPerShareExplanatory
Earnings/(Loss) per Share <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The basic and diluted income/(loss) per share has been calculated by dividing the income/(loss) for the year attributable to ordinary shareholders by the weighted average number of ordinary shares outstanding during the years ended December 31, 2022, 2021 and 2020, respectively. During the years ended December 31, 2022 and 2021 the Company incurred a net loss and therefore all outstanding potential securities were considered anti-dilutive. The amount of potential securities that were excluded from the calculation amounted to 3,134,131 and 6,553,905 shares, respectively. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Earnings/(Loss) Attributable to Owners of the Company:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:26.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Basic<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Diluted<br/>$000s</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted<br/>$000s</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year, attributable to the owners of the Company</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(50,354)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(50,354)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(60,558)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(60,558)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,985 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,985 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) attributable to ordinary shareholders</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(50,354)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(50,354)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(60,558)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(60,558)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,985 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,985 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Weighted-Average Number of Ordinary Shares:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:26.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Basic</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Diluted</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.1pt;font-weight:400;line-height:120%">Issued ordinary shares at January 1,</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">287,796,585</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">287,796,585</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">285,885,025 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">285,885,025 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">285,370,619 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">285,370,619 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effect of shares issued</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">690,772</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">690,772</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">705,958 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">705,958 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">233,048 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">233,048 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effect of dilutive shares (please refer to Note 8)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,252,246 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effect of treasury shares purchased</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,727,922)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,727,922)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Weighted average number of ordinary shares at December 31,</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">284,759,435</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">284,759,435</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">286,590,983 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">286,590,983 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #001544;padding:0 1pt"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">285,603,667 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">292,855,913 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Earnings/(Loss) per Share:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:26.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Basic<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Diluted<br/>$</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted<br/>$</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Basic<br/>$</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Diluted<br/>$</span></td></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Basic and diluted earnings/(loss) per share</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(0.18)</span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(0.18)</span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.21)</span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.21)</span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.02 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.02 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>
CY2022Q4 ptv Potential Securities Excluded From Diluted Eps Calculation
PotentialSecuritiesExcludedFromDilutedEPSCalculation
3134131 shares
CY2021Q4 ptv Potential Securities Excluded From Diluted Eps Calculation
PotentialSecuritiesExcludedFromDilutedEPSCalculation
6553905 shares
CY2022 ifrs-full Disclosure Of Property Plant And Equipment Explanatory
DisclosureOfPropertyPlantAndEquipmentExplanatory
Property and Equipment<div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:27.982%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Cost</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Laboratory and Manufacturing Equipment<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Furniture and<br/>Fixtures<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Computer Equipment and<br/>Software<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Leasehold Improvements<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Construction in<br/>process<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,420 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,452 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,519 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,054 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,852 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">33,297 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions, net of transfers</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,424 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">92 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">183 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,723 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,422 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(323)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(282)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(605)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassifications</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,211 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">248 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,459)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,733 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,452 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,329 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,485 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,116 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,115 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions, net of transfers</span></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">390 </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11 </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">412 </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,362 </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,176 </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(118)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(77)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(195)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(58)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(58)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassifications</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,336 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">58 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">137 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,067 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,598)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2022</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,341</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,510</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,419</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">23,964</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,803</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">43,037</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:27.982%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Accumulated depreciation and impairment loss</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Laboratory and Manufacturing Equipment<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Furniture and<br/>Fixtures<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Computer Equipment and<br/>Software<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Leasehold Improvements<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Construction in<br/>process<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,965)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(454)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,287)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,815)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,520)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,973)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(208)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(174)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,991)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,346)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">251 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">271 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">522 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,686)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(663)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,190)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,806)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(14,344)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation</span></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,082)</span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(212)</span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(107)</span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,444)</span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,845)</span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">53 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">53 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2022</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(7,711)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(875)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,244)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(10,250)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(20,080)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:27.982%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Property and Equipment, net</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Laboratory and Manufacturing Equipment<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Furniture and<br/>Fixtures<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Computer Equipment and<br/>Software<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Leasehold Improvements<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Construction in<br/>process<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,047 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">790 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">139 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,679 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,116 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">26,771 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2022</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,630</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">635</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">174</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,714</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,803</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">22,957</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>Depreciation of property and equipment is included in the General and administrative expenses and Research and development expenses line items in the Consolidated Statements of Comprehensive Income/(Loss). The Company recorded depreciation expense of $5.8 million, $4.3 million and $3.9 million for the years ended December 31, 2022, 2021 and 2020, respectively.
CY2022 ifrs-full Disclosure Of Detailed Information About Property Plant And Equipment Explanatory
DisclosureOfDetailedInformationAboutPropertyPlantAndEquipmentExplanatory
<table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:27.982%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Cost</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Laboratory and Manufacturing Equipment<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Furniture and<br/>Fixtures<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Computer Equipment and<br/>Software<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Leasehold Improvements<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Construction in<br/>process<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,420 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,452 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,519 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,054 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,852 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">33,297 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions, net of transfers</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,424 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">92 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">183 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,723 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,422 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(323)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(282)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(605)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassifications</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,211 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">248 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,459)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,733 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,452 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,329 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,485 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,116 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,115 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions, net of transfers</span></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">390 </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11 </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">412 </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,362 </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,176 </span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Disposals</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(118)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(77)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(195)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(58)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(58)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassifications</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,336 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">58 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">137 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,067 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,598)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2022</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,341</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,510</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,419</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">23,964</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,803</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">43,037</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table>
CY2021Q4 ifrs-full Property Plant And Equipment
PropertyPlantAndEquipment
26771000 usd
CY2022Q4 ifrs-full Property Plant And Equipment
PropertyPlantAndEquipment
22957000 usd
CY2022 ifrs-full Depreciation Expense
DepreciationExpense
5800000 usd
CY2021 ifrs-full Depreciation Expense
DepreciationExpense
4300000 usd
CY2020 ifrs-full Depreciation Expense
DepreciationExpense
3900000 usd
CY2022 ifrs-full Disclosure Of Intangible Assets Explanatory
DisclosureOfIntangibleAssetsExplanatory
Intangible Assets<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Intangible assets consist of licenses of intellectual property acquired by the Group through various agreements with third parties and are recorded at the value of the consideration transferred. Information regarding the cost and accumulated amortization of intangible assets is as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Cost</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Licenses<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">900 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">90 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">990 </span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="border-top:0.5pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25 </span></td><td style="border-top:0.5pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Write-off</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(163)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(21)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2022</span></div></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">831</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Accumulated amortization</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Licenses<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amortization</span></td><td colspan="2" style="border-top:0.5pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1)</span></td><td style="border-top:0.5pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiary</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2022</span></div></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Intangible assets, net</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Licenses<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">987 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2022</span></div></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">831</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Substantially all the intangible asset licenses represent in-process-research-and-development assets since they are still being developed and are not ready for their intended use. As such, these assets are not yet amortized but tested for impairment annually. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During 2022, the company wrote off one of its research intangible assets for which research was ceased in the amount of $162.5 thousand.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company tested all other such intangible assets for impairment as of balance sheet date and concluded that none of such assets were impaired. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2022, Sonde Health, Inc. was deconsolidated and as such $17.5 thousand in net assets were derecognised.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The company had negligible Amortization expense for the years ended December 31, 2022 2021 and 2020.</span></div>
CY2022 ifrs-full Disclosure Of Detailed Information About Intangible Assets Explanatory
DisclosureOfDetailedInformationAboutIntangibleAssetsExplanatory
Information regarding the cost and accumulated amortization of intangible assets is as follows:<table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Cost</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Licenses<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">900 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">90 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance as of December 31, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">990 </span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="border-top:0.5pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25 </span></td><td style="border-top:0.5pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Write-off</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(163)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(21)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2022</span></div></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">831</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table>
CY2022 ifrs-full Impairment Loss Recognised In Profit Or Loss Intangible Assets Other Than Goodwill
ImpairmentLossRecognisedInProfitOrLossIntangibleAssetsOtherThanGoodwill
163000 usd
CY2022 ifrs-full Impairment Loss Recognised In Profit Or Loss Intangible Assets Other Than Goodwill
ImpairmentLossRecognisedInProfitOrLossIntangibleAssetsOtherThanGoodwill
162500 usd
CY2022 ifrs-full Disclosure Of Other Assets Explanatory
DisclosureOfOtherAssetsExplanatory
Other Financial Assets <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other financial assets consist of restricted cash held, which represents amounts that are reserved as collateral against letters of credit with a bank that are issued for the benefit of a landlord in lieu of a security deposit for office space leased by the Group. Information regarding restricted cash was as follows: </span></div><div style="margin-bottom:5.25pt;margin-top:4pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31,</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Restricted cash</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,124</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,124 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total other financial assets</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,124</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,124 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div>
CY2022Q4 ifrs-full Restricted Cash And Cash Equivalents
RestrictedCashAndCashEquivalents
2124000 usd
CY2021Q4 ifrs-full Restricted Cash And Cash Equivalents
RestrictedCashAndCashEquivalents
2124000 usd
CY2022Q4 ifrs-full Other Financial Assets
OtherFinancialAssets
2124000 usd
CY2021Q4 ifrs-full Other Financial Assets
OtherFinancialAssets
2124000 usd
CY2022Q4 ifrs-full Par Value Per Share
ParValuePerShare
0.01
CY2021Q4 ifrs-full Par Value Per Share
ParValuePerShare
0.01
CY2022Q4 ifrs-full Number Of Shares Issued And Fully Paid
NumberOfSharesIssuedAndFullyPaid
278566306 shares
CY2021Q4 ifrs-full Number Of Shares Issued And Fully Paid
NumberOfSharesIssuedAndFullyPaid
287796585 shares
CY2022Q4 ifrs-full Issued Capital
IssuedCapital
5455000 usd
CY2021Q4 ifrs-full Issued Capital
IssuedCapital
5444000 usd
CY2022Q4 ifrs-full Merger Reserve
MergerReserve
138506000 usd
CY2021Q4 ifrs-full Merger Reserve
MergerReserve
138506000 usd
CY2022Q4 ifrs-full Share Premium
SharePremium
289624000 usd
CY2021Q4 ifrs-full Share Premium
SharePremium
289303000 usd
CY2022Q4 ifrs-full Treasury Shares
TreasuryShares
26492000 usd
CY2021Q4 ifrs-full Treasury Shares
TreasuryShares
0 usd
CY2022Q4 ifrs-full Reserve Of Exchange Differences On Translation
ReserveOfExchangeDifferencesOnTranslation
89000 usd
CY2021Q4 ifrs-full Reserve Of Exchange Differences On Translation
ReserveOfExchangeDifferencesOnTranslation
469000 usd
CY2022Q4 ifrs-full Other Reserves
OtherReserves
-14478000 usd
CY2021Q4 ifrs-full Other Reserves
OtherReserves
-40077000 usd
CY2022Q4 ifrs-full Retained Earnings
RetainedEarnings
149516000 usd
CY2021Q4 ifrs-full Retained Earnings
RetainedEarnings
199871000 usd
CY2022Q4 ifrs-full Equity Attributable To Owners Of Parent
EquityAttributableToOwnersOfParent
542220000 usd
CY2021Q4 ifrs-full Equity Attributable To Owners Of Parent
EquityAttributableToOwnersOfParent
593515000 usd
CY2022Q4 ifrs-full Noncontrolling Interests
NoncontrollingInterests
5369000 usd
CY2021Q4 ifrs-full Noncontrolling Interests
NoncontrollingInterests
-9368000 usd
CY2022Q4 ifrs-full Equity
Equity
547589000 usd
CY2021Q4 ifrs-full Equity
Equity
584147000 usd
CY2022Q4 ptv Preferred Share Liability
PreferredShareLiability
27339000 usd
CY2021Q4 ptv Preferred Share Liability
PreferredShareLiability
174017000 usd
CY2022Q4 ptv Minimum Liquidation Preference
MinimumLiquidationPreference
158189000 usd
CY2021Q4 ptv Minimum Liquidation Preference
MinimumLiquidationPreference
170189000 usd
CY2022 ifrs-full Disclosure Of Financial Instruments Explanatory
DisclosureOfFinancialInstrumentsExplanatory
Financial Instruments <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s financial instruments consist of financial liabilities, including preferred shares, convertible notes, warrants and loans payable, as well as financial assets. Many of these financial instruments are presented at fair value with fair value changes recorded through profit and loss.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair Value Process</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For financial instruments measured at fair value under IFRS 9, the change in the fair value is reflected through profit and loss. Using the guidance in IFRS 13, the total business enterprise value and allocable equity of each entity being valued was determined using a market backsolve approach through a recent arm’s length financing round (or a future probable arm's length transaction), market PWERM approach, discounted cash flow income approach, or hybrid approaches. The approaches, in order of strongest fair value evidence, are detailed as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:18.712%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:79.088%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Valuation Method</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Description</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Market – Backsolve</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The market backsolve approach benchmarks the original issue price (OIP) of the company’s latest funding transaction as current value.</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Market/Asset – PWERM</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Under a PWERM, the company value is based upon the probability-weighted present value of expected future investment returns, considering each of the possible future outcomes available to the enterprise. An asset approach may be included as an expected future outcome within the PWERM method. Possible future outcomes can include IPO scenarios, potential SPAC transactions, merger and acquisition transactions as well as other similar exit transactions of the investee.</span></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Arial',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">I</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">ncome Based – DCF</span></div></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The income approach is used to estimate fair value based on the income streams, such as cash flows or earnings, that an asset or business can be expected to generate.</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2022 and 2021, at each measurement date, the fair value of preferred shares and warrant liabilities, including embedded conversion rights that are not bifurcated, as well as investments held at fair value (that are not publicly traded), were determined using the following allocation methods: option pricing model (“OPM”), Probability-Weighted Expected Return Method ("PWERM"), or Hybrid allocation framework. The methods are detailed as follows:</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:18.712%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:79.088%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Allocation Method</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Description</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">OPM</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The OPM model treats preferred stock as call options on the enterprise’s equity value, with exercise prices based on the liquidation preferences of the preferred stock.</span><span style="color:#000000;font-family:'Arial',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></div></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PWERM</span></td><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Under a PWERM, share value is based upon the probability-weighted present value of expected future investment returns, considering each of the possible future outcomes available to the enterprise, as well as the rights of each share class. </span></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Hybrid</span></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The hybrid method (“HM”) is a combination of the PWERM and OPM. Under the hybrid method, multiple liquidity scenarios are weighted based on the probability of the scenarios occurrence, similar to the PWERM, while also utilizing the OPM to estimate the allocation of value in one or more of the scenarios. </span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Valuation policies and procedures are regularly monitored by the Company’s finance group. Fair value measurements, including those categorized within Level 3, are prepared and reviewed on their issuance date and then on an annual basis for reasonableness and compliance with the fair value measurements guidance under IFRS. The Group measures fair values using the following fair value hierarchy that reflects the significance of the inputs used in making the measurements:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:18.712%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:79.088%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Fair Value<br/>Hierarchy Level</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Description</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Level 1</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Inputs that are quoted market prices (unadjusted) in active markets for identical instruments.</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Level 2</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Inputs other than quoted prices included within Level 1 that are observable either directly (i.e. as prices) or indirectly (i.e. derived from prices). </span></td></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Level 3</span></td><td colspan="3" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Inputs that are unobservable. This category includes all instruments for which the valuation technique includes inputs not based on observable data and the unobservable inputs have a significant effect on the instrument’s valuation. </span></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Whilst the Group considers the methodologies and assumptions adopted in fair value measurements as supportable, reasonable and robust, because of the inherent uncertainty of valuation, those estimated values may differ significantly from the values that would have been used had a ready market for the investment existed.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary Preferred Shares Liability and Subsidiary Convertible Notes</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the changes in the Group’s subsidiary preferred shares and convertible note liabilities measured at fair value, which were categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary Preferred Shares<br/>$000s</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary Convertible<br/>Notes<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1, 2020</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">100,989 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Value at issuance</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,750 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,233 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2020 and January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">118,972 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25,000 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Value at issuance</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">37,610 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,215 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Conversion to subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">25,797 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(25,797)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accrued interest - contractual</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">867 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,362)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">175 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">174,017 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,461 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Value at issuance</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">393</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accrued interest – contractual</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">48</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(130,825)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">502 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation - Sonde</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,853)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,403)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31, 2022</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,339</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The change in fair value of preferred shares and convertible notes are recorded in Finance income/(costs) – fair value accounting in the Consolidated Statements of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The table below sets out information about the significant unobservable inputs used at December 31, 2022, in the fair value measurement of the Group’s material subsidiary preferred shares liabilities categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:18.712%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:17.776%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:21.208%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.592%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:21.212%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Fair Value at December 31, 2022</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Valuation Technique</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Unobservable Inputs</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Weighted Average</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity to Decrease in Input</span></td></tr><tr style="height:14pt"><td colspan="3" rowspan="4" style="border-bottom:0.25pt solid #183964;border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">26,820</span></td><td colspan="3" rowspan="4" style="border-bottom:0.25pt solid #001544;border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">PWERM based on pro forma backsolve approach that leverages a Monte Carlo simulation</span></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Estimated Time to Exit</span></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.14</span></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value decrease</span></td></tr><tr style="height:14pt"><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity Discount Rate</span></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">30%</span></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value increase</span></td></tr><tr style="height:14pt"><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Debt Discount Rate</span></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15%</span></td><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value decrease</span></td></tr><tr style="height:14pt"><td colspan="3" style="border-bottom:0.25pt solid #001544;border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Volatility</span></td><td colspan="3" style="border-bottom:0.25pt solid #001544;border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">95%</span></td><td colspan="3" style="border-bottom:0.25pt solid #001544;border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value decrease</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary Preferred Shares Sensitivity </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following summarizes the sensitivity from the assumptions made by the Company with respect to the significant unobservable inputs which are categorized as Level 3 in the fair value hierarchy and used in the fair value measurement of the Group’s subsidiary preferred shares liabilities (Please refer to Note 15):</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:63.697%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Input</span></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary Preferred Share Liability</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31, 2022</span></div></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity Range</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Liability Increase/(Decrease)<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Time to Liquidity</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">- 6 Months</span></div></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,322)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+ 6 Months</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">856 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Volatility</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10)</span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,133)</span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+10%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,200 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount Rate</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5)</span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,035)</span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-bottom:0.25pt solid #001544;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+5%</span></td><td colspan="2" style="border-bottom:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,922 </span></td><td style="border-bottom:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial Assets Held at Fair Value</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Karuna, Vor and Akili Valuation</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna (Nasdaq: KRTX), Vor (Nasdaq: VOR), Akili (Nasdaq: AKLI) and additional immaterial investments are listed entities on an active exchange and as such the fair value as of December 31, 2022, was calculated utilizing the quoted common share price. Please refer to Note 5 for further details.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-style:italic;font-weight:400;line-height:120%">Akili, Gelesis and Sonde</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In accordance with IFRS 9, the Company accounted for its preferred share investments in Akili (until the exchange of such shares to common stock traded on Nasdaq) and Gelesis (until the exchange of such shares to common stock) and accounts for its investment in Sonde (investment in Preferred A-2 and B shares, subsequent to the date of deconsolidation) as financial assets held at fair value through the profit and loss. In addition, the Company accounts for its investment in Gelesis Earn-out shares and Akili Earn-out shares (see Note 5) as investments held at fair value. All the valuations of the aforementioned investments are categorized as Level 3 in the fair value hierarchy due to the use of significant unobservable inputs to value such assets. During the year ended December 31, 2022, the Company recorded such investments at fair value and recognized the change in fair value of the investments as a loss of $30.0 million that was recorded to the Consolidated Statements of Comprehensive Income/(Loss) in the line item Gain/(loss) on investments held at fair value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the changes in all the Group’s investments held at fair value, which were categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:5.25pt;text-align:justify"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:87.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.720%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$'000s</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1, 2020</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">154,445 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash purchase of Gelesis preferred shares (please refer to Note 6)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,000 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash purchase of Vor preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,150 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(Loss) on changes in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">41,297 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2020 and January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">206,892 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash purchase of Vor preferred shares</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">500 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassification of Vor from level 3 to level 1</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(33,365)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gain/(Loss) on changes in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">65,505 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1, 2022 before allocation of associate loss to long-term interest</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">239,533 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of Sonde</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,168 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis – New Investment – Earn out Shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,214 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Exchange of Gelesis preferred shares to Gelesis common shares </span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(92,303)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reclassification of Akili to level 1 investment</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(128,764)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(31,253)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2022</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">12,593</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The change in fair value of investments held at fair value are recorded in Gain/(loss) on investments held at fair value in the Consolidated Statements of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The table below sets out information about the significant unobservable inputs used at December 31, 2022, in the fair value measurement of the Group’s material preferred share investments held at fair value categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:19.024%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.592%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:23.080%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:15.592%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:21.212%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Fair Value at December 31, 2022</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Valuation Technique</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Unobservable Inputs</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Weighted Average</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity to Decrease in Input</span></td></tr><tr style="height:11pt"><td colspan="3" rowspan="2" style="border-bottom:0.25pt solid #001544;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,403</span></td><td colspan="3" rowspan="2" style="border-bottom:0.25pt solid #001544;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:middle"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Market Backsolve &amp; OPM</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Estimated time to exit</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2.00</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:middle"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value decrease</span></td></tr><tr style="height:11pt"><td colspan="3" style="border-bottom:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Volatility</span></td><td colspan="3" style="border-bottom:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">55%</span></td><td colspan="3" style="border-bottom:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:middle"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair value decrease</span></td></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As the material investments held at fair value categorized as level 3 in the fair value hierarchy are based on a market backsolve approach using a recent arm's length transaction the change in unobservable inputs in reasonably possible scenarios has an immaterial impact on the financial statements.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrants</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrants issued by subsidiaries within the Group are classified as liabilities, as they will be settled in a variable number of preferred shares. The following table summarizes the changes in the Group’s subsidiary warrant liabilities, which were categorized as Level 3 in the fair value hierarchy:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:87.043%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.757%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary Warrant Liability<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1, 2020</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,997 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrant Issuance</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">92 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value - finance costs (income)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">117 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2020 and January 1, 2021</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,206 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value - finance costs (income)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,419)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,787 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in fair value - finance costs (income)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6,740)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31, 2022</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The change in fair value of warrants are recorded in Finance income/(costs) – fair value accounting in the Consolidated Statements of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In connection with various amendments to its 2010 Loan and Security Agreement, Follica issued Series A-1 preferred share warrants at various dates in 2013 and 2014. In 2017, in conjunction with the issuance of convertible notes, the exercise price of the warrants was adjusted to $0.07 per share. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In connection with the September 2, 2021 Oxford Finance LLC loan issuance, Vedanta also issued Oxford Finance LLC 12,886 Series C-2 preferred share warrants with an exercise price of $23.28 per share, expiring September 2030.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of the warrant liabilities was immaterial as of December 31, 2022 due to the decline in the fair value of the underlying preferred shares in the Follica warrant. See also Note 15 for the fair value of Follica preferred share liabilities.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term Note from Associate</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On December 7, 2021, Gelesis issued PureTech a $15.0 million note to be repaid the earlier of three business days after the closing of the business combination of Gelesis with Capstar Special Acquisition Corp ("Capstar"), or 30 days following the termination of such business combination. In the event of the business combination termination, the Company, who represented the majority of the note holders, could have elected to convert the note at the next equity financing at a discount of 25% from the financing price. The note bore interest at a rate of 10% per annum.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The note was repaid by Gelesis in January 2022 due to the closing of the business combination between Gelesis and Capstar on January 13, 2022.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Note from Associate </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On July 27, 2022, PureTech, as a lender, entered into an unsecured Short Term Promissory Note ("Note") with Gelesis (GLS), as a borrower, in the amount of $15.0 million. The Note bears an annual interest rate of 15% per annum and accrues until the note is repaid. The term of the Note is the earlier of December 31, 2023 or five business days following the consummation of a qualified financing by Gelesis. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In case of default, PureTech will be issued a warrant which shall entitle PureTech to purchase at an exercise price per share of $0.01 a number of shares of Gelesis common Stock equal to (i) (A) 0.2 multiplied by (B) the amount of outstanding principal and accrued interest under the Note as of the date of conversion described below, divided by (ii) the volume weighted average price of each share of Common Stock, as reported by the New York Stock Exchange, for the last five (5) trading days ("the “Common Stock VWAP”) occurring immediately prior to the date of exercise. In addition, PureTech will have the option to convert the amount of outstanding principal and accrued interest under the Note into a number of shares of Gelesis Common Stock (the “Conversion Securities”) equal to (i) the amount of outstanding principal and accrued interest under the Note as of the date of such conversion, divided by (ii) the lesser of the price per share of (A) the Gelesis common Stock, as reported by the New York Stock Exchange, as of 4:00 P.M. Eastern Time on the date of the conversion notice or (B) the Common Stock VWAP as of the day prior to the date of the conversion notice.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Based on the terms of the note, the note is required to be measured at fair value with changes in fair value recorded through profit and loss. The fair value of the note as of December 31, 2022 was $16.5 million. During the year ended December 31, 2022 the Group recorded $963 thousand of interest income and a gain of $539 thousand for the change in the fair value of the note. The change in the fair value of the note was recorded in the line item Other Income/(expense) in the Consolidated Statements of Comprehensive Income/(Loss).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The note was valued using a discounted cash flow approach of the probability weighted future returns on the note, using a discount rate of 28.9%. Increasing or decreasing the discount rate by 5.0% will decrease or increase the value, respectively, by approximately $0.4 million. Also, increasing the estimated term to a qualified financing by 6 months (estimated as 3 months from December 31, 2022) will decrease the fair value by approximately $0.9 million.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsequent to balance sheet date, on April 10, 2023, the NYSE commenced proceedings to delist the common stock of Gelesis from the NYSE due to Gelesis ceasing to meet certain conditions to trade on such stock exchange. Trading in Gelesis’s common stock was suspended immediately, and it was subsequently delisted from the NYSE. The common stock of Gelesis is currently available for trading in the over-the-counter (“OTC”) market under the symbol GLSH. See Note 26 for additional details, including information related to an additional note issued by Gelesis to the Group after balance sheet date.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fair Value Measurement and Classification</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of financial instruments by category at December 31, 2022 and 2021:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:27.360%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="21" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Carrying Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="12" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Fair Value</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Financial Assets<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Financial Liabilities<br/>$000s</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 1<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 2<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 3<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Financial assets:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Money Markets</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">95,249</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">95,249</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">95,249</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term investments</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">200,229</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">200,229</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">200,229</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Note from associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16,501</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16,501</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16,501</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">251,892</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">239,299</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">12,593</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">251,892</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total financial assets</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">575,738</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">534,777</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">29,094</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">575,738</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Financial liabilities:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary warrant liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,339</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,339</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,339</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,345</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,097</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">248</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,345</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share based liability awards</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,932</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,396</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,537</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,932</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total financial liabilities</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,664</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,396</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,097</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">29,171</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,664</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Issued by a diverse group of corporations, largely consisting of financial institutions, virtually all of which are investment grade.</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Included within Cash and cash equivalents</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Outstanding receivables are owed primarily by government agencies and large corporations, virtually all of which are investment grade.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of balance sheet date the long term loan book value (see Note 20) approximated its fair value due to its variable rate.</span></div><div style="margin-bottom:2pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:27.360%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="21" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td></tr><tr><td colspan="3" style="padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Carrying Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="12" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Fair Value</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Assets<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Liabilities<br/>$000s</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 1<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 2<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 3<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial assets:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Money Markets</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">432,649 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">432,649 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">432,649 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term note from associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,120 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,120 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,120 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">493,888 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">254,355 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">239,533 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">493,888 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,174 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,174 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,174 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total financial assets</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">944,832 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">687,005 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,174 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">254,653 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">944,832 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial liabilities:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary warrant liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,787 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,787 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,787 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">174,017 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">174,017 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">174,017 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,641 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,945 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,696 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,641 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share based liability awards</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,362 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,081 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,281 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,362 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total financial liabilities</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">192,808 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,081 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,945 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">184,781 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">192,808 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Issued by a diverse group of corporations, largely consisting of financial institutions, virtually all of which are investment grade. Included within Cash and cash equivalents</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Balance prior to share of associate loss allocated to long-term interest (please refer to Note 5).</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Outstanding receivables are owed primarily by government agencies, virtually all of which are investment grade.</span></div>
CY2022Q4 ifrs-full Financial Assets At Fair Value
FinancialAssetsAtFairValue
575738000 usd
CY2022 ifrs-full Disclosure Of Sensitivity Analysis Of Fair Value Measurement To Changes In Unobservable Inputs Liabilities Explanatory
DisclosureOfSensitivityAnalysisOfFairValueMeasurementToChangesInUnobservableInputsLiabilitiesExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following summarizes the sensitivity from the assumptions made by the Company with respect to the significant unobservable inputs which are categorized as Level 3 in the fair value hierarchy and used in the fair value measurement of the Group’s subsidiary preferred shares liabilities (Please refer to Note 15):</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:63.697%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.501%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:16.502%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Input</span></td><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Subsidiary Preferred Share Liability</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31, 2022</span></div></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Sensitivity Range</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Liability Increase/(Decrease)<br/>$000s</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Time to Liquidity</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">- 6 Months</span></div></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,322)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+ 6 Months</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">856 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Volatility</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10)</span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,133)</span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+10%</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,200 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Discount Rate</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5)</span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">%</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,035)</span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-bottom:0.25pt solid #001544;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">+5%</span></td><td colspan="2" style="border-bottom:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,922 </span></td><td style="border-bottom:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>
CY2022 ifrs-full Disclosure Of Fair Value Measurement Explanatory
DisclosureOfFairValueMeasurementExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The fair value of financial instruments by category at December 31, 2022 and 2021:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:27.360%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="21" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Carrying Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="12" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Fair Value</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Financial Assets<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Financial Liabilities<br/>$000s</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 1<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 2<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Level 3<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Financial assets:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Money Markets</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1,2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">95,249</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">95,249</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">95,249</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term investments</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">200,229</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">200,229</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">200,229</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Note from associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16,501</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16,501</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">16,501</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">251,892</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">239,299</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">12,593</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">251,892</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total financial assets</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">575,738</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">534,777</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">29,094</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">575,738</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Financial liabilities:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary warrant liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,339</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,339</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,339</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,345</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,097</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">248</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,345</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share based liability awards</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,932</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,396</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,537</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,932</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total financial liabilities</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,664</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,396</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,097</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">29,171</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,664</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Issued by a diverse group of corporations, largely consisting of financial institutions, virtually all of which are investment grade.</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Included within Cash and cash equivalents</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Outstanding receivables are owed primarily by government agencies and large corporations, virtually all of which are investment grade.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of balance sheet date the long term loan book value (see Note 20) approximated its fair value due to its variable rate.</span></div><div style="margin-bottom:2pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:27.360%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="21" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td></tr><tr><td colspan="3" style="padding:0 1pt"><div style="margin-bottom:10pt"><span><br/></span></div></td><td colspan="6" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Carrying Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="12" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Fair Value</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Assets<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Financial Liabilities<br/>$000s</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 1<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 2<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Level 3<br/>$000s</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial assets:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Money Markets</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">432,649 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">432,649 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">432,649 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term note from associate</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,120 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,120 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,120 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">493,888 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">254,355 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">239,533 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">493,888 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,174 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,174 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,174 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total financial assets</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">944,832 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">687,005 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,174 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">254,653 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">944,832 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Financial liabilities:</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary warrant liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,787 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,787 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,787 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">174,017 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">174,017 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">174,017 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,641 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,945 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,696 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,641 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share based liability awards</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,362 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,081 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,281 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,362 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total financial liabilities</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">192,808 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,081 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,945 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">184,781 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">192,808 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Issued by a diverse group of corporations, largely consisting of financial institutions, virtually all of which are investment grade. Included within Cash and cash equivalents</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Balance prior to share of associate loss allocated to long-term interest (please refer to Note 5).</span></div><div style="margin-bottom:2pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Outstanding receivables are owed primarily by government agencies, virtually all of which are investment grade.</span></div>
CY2022Q4 ifrs-full Financial Liabilities At Fair Value
FinancialLiabilitiesAtFairValue
35664000 usd
CY2021Q4 ifrs-full Financial Assets At Fair Value
FinancialAssetsAtFairValue
944832000 usd
CY2021Q4 ifrs-full Financial Liabilities At Fair Value
FinancialLiabilitiesAtFairValue
192808000 usd
CY2022Q4 ifrs-full Current Financial Liabilities
CurrentFinancialLiabilities
2345000 usd
CY2021Q4 ifrs-full Current Financial Liabilities
CurrentFinancialLiabilities
4641000 usd
CY2022 ifrs-full Disclosure Of Noncontrolling Interests Explanatory
DisclosureOfNoncontrollingInterestsExplanatory
Non-Controlling Interest<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2022, Sonde Health, Inc was deconsolidated and therefore transferred retroactively to the Non-Controlled Founded Entity segment. See Note 5. Investments Held at Fair Value.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company has revised in the 2022 financial statements the prior period financial information related to the segmentation of NCI, to conform to the presentation as of and for the year ending December 31, 2022. Please refer to Note 4 “Segment Information” for further details regarding reportable segments.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the changes in the equity classified non-controlling ownership interest in subsidiaries by reportable segment:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:39.617%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.759%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Non-Controlled Founded<br/>Entities</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Parent Company &amp; Other<br/>$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1, 2020 *</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,682)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,465 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11,016)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">593 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(17,639)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of comprehensive loss</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(191)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(905)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(306)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,417)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity settled share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">305 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,395 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">122 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,822 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2020 and January 1, 2021 *</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,567)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,966 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11,181)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">574 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(16,209)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of comprehensive loss</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(96)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,634)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(436)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,151)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">NCI exercise of share-based awards in subsidiaries - change in NCI interest</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,922)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,922)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity settled share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,224 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">32 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,252 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Acquisition of a subsidiary non controlling interest</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,668 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,668 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,634 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11,585)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">583 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(9,368)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of comprehensive income (loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,604 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(330)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,290 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">NCI exercise of share-based awards </span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,164)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,164)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,904 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,904 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity settled share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,703 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,711 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2022</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,778</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">592</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,369</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">*    Revised to reclassify Sonde to the Non-controlled Founded Entities segment to comply with current period classification. See Note 4.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following tables summarize the financial information related to the Group’s subsidiaries with material non-controlling interests, aggregated for interests in similar entities, and before and after intra group eliminations.</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.565%"><tr><td style="width:1.0%"/><td style="width:51.325%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.793%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.793%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td style="width:1.0%"/><td style="width:10.793%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.796%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="12" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Internal<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Controlled Founded Entities<br/>$000s</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Intra-group eliminations</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Statement of Comprehensive Loss</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="display:none"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">12,202</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">12,202</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">98,633</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,003</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99,636</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">98,633</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,003</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99,636</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Statement of Financial Position</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="display:none"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,341</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(100)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,241</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">76,635</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(11,057)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">65,578</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Net assets/(liabilities)</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(41,294)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,957</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(30,336)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2022, Controlled Founded Entities with non-controlling interests primarily include Follica Incorporated, Entrega Inc., and Vedanta Biosciences, Inc. Ownership interests of the non-controlling interests in Follica Incorporated, Entrega Inc., and Vedanta Biosciences, Inc are 19.9 percent, 11.7 percent, and 12.2 percent, respectively. In addition, Non-controlling interests include the amounts recorded for subsidiary stock options, with the vast majority comprising of Vedanta stock options.</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:51.474%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="12" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities<br/> $000s</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Intra-group eliminations</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Statement of Comprehensive Loss</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="display:none"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,771 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,771 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(50,436)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">792 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(49,644)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other comprehensive income/(loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(50,436)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">792 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(49,644)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Statement of Financial Position</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="display:none"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">66,279 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(161)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">66,118 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total liabilities</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">228,856 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(10,755)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">218,101 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Net assets/(liabilities)</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(162,576)</span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,594 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(151,982)</span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2021, Controlled Founded Entities with non-controlling interests primarily include, Follica Incorporated, Sonde Health Inc., Entrega Inc. and Vedanta Biosciences, Inc. Ownership interests of the non-controlling interests in Follica Incorporated, Sonde Health Inc., and Vedanta Biosciences, Inc are 19.9 percent, 11.7 percent, 6.2 percent and 3.7 percent, respectively. In addition, Non-controlling interests include the amounts recorded for subsidiary stock options, with the vast majority comprising of Vedanta stock options.</span></div><div style="margin-bottom:2pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:51.474%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="12" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">For the year ended December 31</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities<br/> $000s</span></div></td><td colspan="3" style="display:none"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Intra-group eliminations</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Statement of Comprehensive Loss</span></td><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="display:none"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #000;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total revenue</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,267 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,957 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,224 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,407)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(53,535)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="3" style="display:none"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,073 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(54,869)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:top"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total comprehensive income/(loss) for the year</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,407)</span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(53,535)</span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,073 </span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(54,869)</span></td><td style="border-bottom:0.25pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2020, Internal segment with non-controlling interests includes Alivio, Controlled Founded Entities with non-controlling interests primarily include, Follica Incorporated, Sonde Health Inc., and Vedanta Biosciences, Inc. Ownership interests of the non-controlling interests in Alivio Therapeutics, Inc., Follica Incorporated, Sonde Health Inc., and Vedanta Biosciences, Inc are 8.1 percent, 19.9 percent, 4.5 percent and 0.4 percent, respectively. In addition, Non-controlling interests include the amounts recorded for subsidiary stock options, with the vast majority comprising of Vedanta stock options.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On June 11, 2021, PureTech acquired the remaining 17.1 percent of the minority non-controlling interests of Alivio (after exercise of all in the money stock options) increasing its ownership to 100.0 percent of Alivio. The consideration for such non controlling interests amounted to $1.2 million, to be paid in three equal installments, with the first installment of $0.4 million paid at the effective date of the transaction and two additional installment to be paid upon the occurrence of certain contingent events. The Group recorded a contingent consideration liability of $0.6 million at fair value for the two additional installments, resulting in a total acquisition cost of $1.0 million. The excess of the consideration paid over the book value of the non-controlling interest of approximately $9.6 million was recorded directly as a charge to shareholders’ equity. The second installment of $0.4 million was paid in July 2021, upon the occurrence of the contingent event specified in the agreement. The contingent consideration liability is adjusted to fair value at the end of each reporting period with changes in fair value recorded in earnings. Changes in fair value of the aforementioned contingent consideration liability were not material. As of December 31, 2022, the remaining contingent liability was reduced to zero as the second contingent event did not occur.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On December 1, 2021, options holders in Entrega exercised options into shares of common stock, increasing the NCI interest held from 0.2 percent to 11.7 percent. During 2021 option holders in Vedanta exercised options and increased the NCI interest to 3.7 percent. The exercise of the options resulted in an increase in the NCI share in Entrega's and Vedanta's shareholder's deficit of $5.9 million. The consideration paid by NCI ($0.1 million) together with the increase in NCI share in Entrega's and Vedanta's shareholder deficit ( $5.9 million) amounted to $6.0 million and was recorded as a gain directly in shareholders' equity.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On February 15, 2022, option holders in Vedanta exercised options into shares of common stock, increasing the NCI interest held from 3.7 percent to 12.2 percent. The exercise of the options resulted in an increase in the NCI share in Vedanta's shareholder's deficit of $15.2 million. The consideration paid by NCI ($7.2 thousand) together with the increase in NCI share in Vedanta's shareholder deficit ($15.2 million) amounted to $15.2 million and was recorded as a gain directly in shareholders' equity.</span></div>
CY2022 ifrs-full Disclosure Of Interests In Subsidiaries Explanatory
DisclosureOfInterestsInSubsidiariesExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes the changes in the equity classified non-controlling ownership interest in subsidiaries by reportable segment:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:39.617%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.759%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Internal</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Controlled Founded Entities</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Non-Controlled Founded<br/>Entities</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Parent Company &amp; Other<br/>$000s</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1, 2020 *</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,682)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,465 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11,016)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">593 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(17,639)</span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of comprehensive loss</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(191)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(905)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(306)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,417)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity settled share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">305 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,395 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">122 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,822 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">24 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2020 and January 1, 2021 *</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(8,567)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,966 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11,181)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">574 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(16,209)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of comprehensive loss</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(96)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,634)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(436)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,151)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">NCI exercise of share-based awards in subsidiaries - change in NCI interest</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,922)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,922)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity settled share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,224 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">32 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,252 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Acquisition of a subsidiary non controlling interest</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,668 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,668 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31, 2021 and January 1, 2022</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,634 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11,585)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">583 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(9,368)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share of comprehensive income (loss)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,604 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(330)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,290 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">NCI exercise of share-based awards </span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,164)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,164)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deconsolidation of subsidiaries</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,904 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,904 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity settled share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,703 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,711 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance as of December 31, 2022</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,778</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">592</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,369</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">*    Revised to reclassify Sonde to the Non-controlled Founded Entities segment to comply with current period classification. See Note 4.</span></div>
CY2021Q2 ifrs-full Contingent Consideration Recognised As Of Acquisition Date
ContingentConsiderationRecognisedAsOfAcquisitionDate
600000 usd
CY2021Q2 ifrs-full Consideration Paid Received
ConsiderationPaidReceived
9600000 usd
CY2022Q4 ifrs-full Trade And Other Current Payables
TradeAndOtherCurrentPayables
54840000 usd
CY2021Q4 ifrs-full Trade And Other Current Payables
TradeAndOtherCurrentPayables
35817000 usd
CY2022 ifrs-full Disclosure Of Borrowings Explanatory
DisclosureOfBorrowingsExplanatory
Long-term loan<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In September 2020, Vedanta entered into a $15.0 million loan and security agreement with Oxford Finance LLC. The loan is secured by Vedanta's assets, including equipment, inventory and intellectual property. The loan bears a floating interest rate of 7.7 percent plus the greater of (i) 30 day U.S. Dollar LIBOR reported in the Wall Street Journal or (ii) 0.17 percent. The loan matures September 2025 and requires interest only payments prior to 2023. The loan also carries a final fee upon full repayment of 7.0 percent of the original principal, or $1.1 million. As part of the loan agreement, Vedanta also issued Oxford Finance LLC 12,886 Series C-2 preferred share warrants with an exercise price of $23.28 per share, expiring September 2030. The outstanding loan balance totaled approximately $15.4 million as of December 31, 2022.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes long-term loan activity for the years ended December 31, 2022 and 2021:</span></div><div><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:75.187%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.757%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Long-term loan</span></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="9" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1,</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15,118</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,818 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accrued interest</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,755</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,502 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest paid</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,436)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1,201)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(38)</span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at December 31,</span></div></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15,400</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,118 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes Vedanta's future principal payments for the long-term loan as of December 31, 2022:</span></div><div style="margin-bottom:2pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:51.474%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Balance Type</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2023</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2024</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2025</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Principal</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,156 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,625 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,219 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,000 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance of accreted premium net of unamortized issuance costs</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">400 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15,400</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The long-term loan is presented as follows in the Statement of Financial Position as of December 31, 2022 and 2021: </span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:middle"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Long-term loan</span></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="9" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current portion of Long-term loan</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,156</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">857 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term loan</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,244</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,261 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total Long-term loan</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15,400</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,118 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>
CY2022 ifrs-full Disclosure Of Trade And Other Payables Explanatory
DisclosureOfTradeAndOtherPayablesExplanatory
Trade and Other Payables <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Information regarding Trade and other payables was as follows: </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31,</span></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade payables</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">26,504</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,346 </span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Accrued expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">24,518</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,309 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income tax payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">57</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">57 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Liability settled share based awards</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,805</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,703 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,957</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,403 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total trade and other payables</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">54,840</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35,817 </span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div>
CY2022Q4 ifrs-full Trade And Other Current Payables To Trade Suppliers
TradeAndOtherCurrentPayablesToTradeSuppliers
26504000 usd
CY2021Q4 ifrs-full Trade And Other Current Payables To Trade Suppliers
TradeAndOtherCurrentPayablesToTradeSuppliers
11346000 usd
CY2022Q4 ifrs-full Accruals Classified As Current
AccrualsClassifiedAsCurrent
24518000 usd
CY2021Q4 ifrs-full Accruals Classified As Current
AccrualsClassifiedAsCurrent
17309000 usd
CY2022Q4 ptv Trade Payables Income Tax Payable
TradePayablesIncomeTaxPayable
57000 usd
CY2021Q4 ptv Trade Payables Income Tax Payable
TradePayablesIncomeTaxPayable
57000 usd
CY2022Q4 ptv Other Payables Liability Settled Share Based Awards
OtherPayablesLiabilitySettledShareBasedAwards
1805000 usd
CY2021Q4 ptv Other Payables Liability Settled Share Based Awards
OtherPayablesLiabilitySettledShareBasedAwards
4703000 usd
CY2022Q4 ifrs-full Other Current Payables
OtherCurrentPayables
1957000 usd
CY2021Q4 ifrs-full Other Current Payables
OtherCurrentPayables
2403000 usd
CY2021Q4 ifrs-full Borrowings
Borrowings
15118000 usd
CY2020Q4 ifrs-full Borrowings
Borrowings
14818000 usd
CY2022 ptv Borrowings Accrued Interest
BorrowingsAccruedInterest
1755000 usd
CY2021 ptv Borrowings Accrued Interest
BorrowingsAccruedInterest
1502000 usd
CY2022 ptv Borrowings Interest Paid
BorrowingsInterestPaid
1436000 usd
CY2021 ptv Borrowings Interest Paid
BorrowingsInterestPaid
-1201000 usd
CY2022 ptv Borrowings Other
BorrowingsOther
38000 usd
CY2021 ptv Borrowings Other
BorrowingsOther
0 usd
CY2022Q4 ifrs-full Borrowings
Borrowings
15400000 usd
CY2021Q4 ifrs-full Borrowings
Borrowings
15118000 usd
CY2022 ifrs-full Disclosure Of Borrowing Costs Explanatory
DisclosureOfBorrowingCostsExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table summarizes Vedanta's future principal payments for the long-term loan as of December 31, 2022:</span></div><div style="margin-bottom:2pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:51.474%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Balance Type</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2023</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2024</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2025</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Principal</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,156 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,625 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,219 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,000 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance of accreted premium net of unamortized issuance costs</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">400 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total</span></td><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15,400</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>
CY2022 ifrs-full Additions To Rightofuse Assets
AdditionsToRightofuseAssets
163000 usd
CY2022 ifrs-full Disclosure Of Detailed Information About Borrowings Explanatory
DisclosureOfDetailedInformationAboutBorrowingsExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The long-term loan is presented as follows in the Statement of Financial Position as of December 31, 2022 and 2021: </span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:middle"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Long-term loan</span></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="9" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current portion of Long-term loan</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,156</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">857 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term loan</span></td><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,244</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,261 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total Long-term loan</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15,400</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,118 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>
CY2022Q4 ifrs-full Current Portion Of Longterm Borrowings
CurrentPortionOfLongtermBorrowings
5156000 usd
CY2021Q4 ifrs-full Current Portion Of Longterm Borrowings
CurrentPortionOfLongtermBorrowings
857000 usd
CY2022Q4 ifrs-full Longterm Borrowings
LongtermBorrowings
10244000 usd
CY2021Q4 ifrs-full Longterm Borrowings
LongtermBorrowings
14261000 usd
CY2022Q4 ifrs-full Borrowings
Borrowings
15400000 usd
CY2021Q4 ifrs-full Borrowings
Borrowings
15118000 usd
CY2022 ifrs-full Disclosure Of Leases Explanatory
DisclosureOfLeasesExplanatory
Leases <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The activity related to the Group’s right of use asset and lease liability for the years ended December 31, 2022 and 2021 is as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:75.187%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.757%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Right of use asset, net</span></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="9" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1,</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">17,166</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20,098 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">163</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">739 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tenant improvement - lease incentive</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(733)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,047)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,938)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31,</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,281</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,166 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:75.187%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.757%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total lease liability</span></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="9" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1,</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">32,990</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35,348 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">163</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,016 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash paid for rent - principal - financing cash flow</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(4,025)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,375)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash paid for rent - interest </span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1,982)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,181)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,982</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,181 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31,</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">29,128</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">32,990 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation of the right-of-use assets, which virtually all consist of leased real estate, is included in the General and administrative expenses and Research and development expenses line items in the Consolidated Statements of Comprehensive Income/(Loss). The Company recorded depreciation expense of $3.0 million, $2.9 million and $2.7 million for the years ended December 31, 2022, 2021 and 2020 respectively.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following details the short term and long-term portion of the lease liability as of December 31, 2022 and 2021:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:75.187%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.757%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:middle"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total lease liability</span></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="9" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term Portion of Lease Liability</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,972</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,950 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term Portion of Lease Liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">24,155</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">29,040 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total Lease Liability</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">29,128</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">32,990 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table details the future maturities of the lease liability, showing the undiscounted lease payments to be paid after the reporting date:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:87.043%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.757%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="6" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Less than one year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,673</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">One to two years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,763</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Two to three years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,168</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Three to four years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,419</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Four to five years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,551</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">More than five years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7,483</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total undiscounted lease maturities</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,056</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,928</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total lease liability</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">29,128</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the year ended December 31, 2019, PureTech entered into a lease agreement for certain premises consisting of approximately 50,858 rentable square feet of space located at 6 Tide Street. The lease commenced on April 26, 2019 (“Commencement Date”) for an initial term consisting of ten years and three months and there is an option to extend for two consecutive periods of five years each. The Company assessed at lease commencement date whether it is reasonably certain to exercise the extension options and deemed such options not reasonably certain to be exercised. The Company will reassess whether it is reasonably certain to exercise the options only if there is a significant event or significant changes in circumstances within its control. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On June 26, 2019, PureTech executed a sublease agreement with Gelesis. The lease is for the approximately 9,446 rentable square feet located on the sixth floor of the Company’s former offices at the 501 Boylston Street building. The sublessee obtained possession of the premises on June 1, 2019 and the rent period term began on June 1, 2019 and expires on August 31, 2025. The sublease was determined to be a finance lease. As of December 31, 2022, the balances related to the sublease were as follows:</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:87.043%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.757%"/><td style="width:0.1%"/></tr><tr style="height:20pt"><td colspan="3" rowspan="2" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total lease receivable</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="6" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term Portion of Lease Receivable</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">450 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term Portion of Lease Receivable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">835 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total Lease Receivable</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,285</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table details the future maturities of the lease receivable, showing the undiscounted lease payments to be received after the reporting date:</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:87.043%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.757%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="6" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Less than one year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">513</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">One to two years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">523</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Two to three years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">353</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total undiscounted lease receivable</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,389</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Unearned Finance income</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">103</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Net investment in the lease</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,285</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:1pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On August 6, 2019, PureTech executed a sublease agreement with Dewpoint Therapeutics, Inc. (“Dewpoint”). The sublease was for approximately 11,852 rentable square feet located on the third floor of the 6 Tide Street building, where the Company’s offices are currently located. Dewpoint obtained possession of the premises on September 1, 2019 with a rent period term that began on September 1, 2019, and expired on August 31, 2021. The sublease was determined to be an operating lease.</span></div>Rental income recognized by the Company during the years ended December 31, 2021 and 2020 was $0.6 million and $1.1 million, respectively and is included in the Other income/(expense) line item in the Consolidated Statements of Comprehensive Income/(Loss).
CY2022 ifrs-full Disclosure Of Quantitative Information About Rightofuse Assets Explanatory
DisclosureOfQuantitativeInformationAboutRightofuseAssetsExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The activity related to the Group’s right of use asset and lease liability for the years ended December 31, 2022 and 2021 is as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:75.187%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.757%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Right of use asset, net</span></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="9" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Balance at January 1,</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">17,166</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">20,098 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Additions</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">163</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">739 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tenant improvement - lease incentive</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(733)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Depreciation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,047)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,938)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Balance at December 31,</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,281</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">17,166 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>
CY2021Q4 ifrs-full Rightofuse Assets
RightofuseAssets
17166000 usd
CY2020Q4 ifrs-full Rightofuse Assets
RightofuseAssets
20098000 usd
CY2020Q4 ifrs-full Rightofuse Assets
RightofuseAssets
20098000 usd
CY2020 ptv Percentage Vote And Value Of Subsidiaries Included In The Group Consolidated Federal Tax Return
PercentageVoteAndValueOfSubsidiariesIncludedInTheGroupConsolidatedFederalTaxReturn
0.80
CY2021 ifrs-full Additions To Rightofuse Assets
AdditionsToRightofuseAssets
739000 usd
CY2022 ptv Tenant Improvements Right Of Use Assets
TenantImprovementsRightOfUseAssets
0 usd
CY2021 ptv Tenant Improvements Right Of Use Assets
TenantImprovementsRightOfUseAssets
-733000 usd
CY2022 ifrs-full Depreciation Rightofuse Assets
DepreciationRightofuseAssets
3047000 usd
CY2021 ifrs-full Depreciation Rightofuse Assets
DepreciationRightofuseAssets
2938000 usd
CY2022Q4 ifrs-full Rightofuse Assets
RightofuseAssets
14281000 usd
CY2021Q4 ifrs-full Rightofuse Assets
RightofuseAssets
17166000 usd
CY2021Q4 ifrs-full Lease Liabilities
LeaseLiabilities
32990000 usd
CY2020Q4 ifrs-full Lease Liabilities
LeaseLiabilities
35348000 usd
CY2022 ptv Additions Lease Liabilities
AdditionsLeaseLiabilities
163000 usd
CY2021 ptv Additions Lease Liabilities
AdditionsLeaseLiabilities
1016000 usd
CY2022 ifrs-full Payments Of Lease Liabilities Classified As Financing Activities
PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities
4025000 usd
CY2021 ifrs-full Payments Of Lease Liabilities Classified As Financing Activities
PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities
3375000 usd
CY2022 ifrs-full Cash Outflow For Leases
CashOutflowForLeases
1982000 usd
CY2021 ifrs-full Cash Outflow For Leases
CashOutflowForLeases
2181000 usd
CY2022 ifrs-full Interest Expense On Lease Liabilities
InterestExpenseOnLeaseLiabilities
1982000 usd
CY2021 ifrs-full Interest Expense On Lease Liabilities
InterestExpenseOnLeaseLiabilities
2181000 usd
CY2022Q4 ifrs-full Lease Liabilities
LeaseLiabilities
29128000 usd
CY2021Q4 ifrs-full Lease Liabilities
LeaseLiabilities
32990000 usd
CY2022 ifrs-full Depreciation Rightofuse Assets
DepreciationRightofuseAssets
3000000 usd
CY2021 ifrs-full Depreciation Rightofuse Assets
DepreciationRightofuseAssets
2900000 usd
CY2020 ifrs-full Depreciation Rightofuse Assets
DepreciationRightofuseAssets
2700000 usd
CY2022Q4 ifrs-full Current Lease Liabilities
CurrentLeaseLiabilities
4972000 usd
CY2021Q4 ifrs-full Current Lease Liabilities
CurrentLeaseLiabilities
3950000 usd
CY2022Q4 ifrs-full Noncurrent Lease Liabilities
NoncurrentLeaseLiabilities
24155000 usd
CY2021Q4 ifrs-full Noncurrent Lease Liabilities
NoncurrentLeaseLiabilities
29040000 usd
CY2022Q4 ifrs-full Lease Liabilities
LeaseLiabilities
29128000 usd
CY2021Q4 ifrs-full Lease Liabilities
LeaseLiabilities
32990000 usd
CY2022 ifrs-full Disclosure Of Maturity Analysis Of Operating Lease Payments Explanatory
DisclosureOfMaturityAnalysisOfOperatingLeasePaymentsExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table details the future maturities of the lease liability, showing the undiscounted lease payments to be paid after the reporting date:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:87.043%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.757%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="6" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Less than one year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,673</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">One to two years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">6,763</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Two to three years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,168</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Three to four years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,419</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Four to five years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,551</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">More than five years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7,483</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total undiscounted lease maturities</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">35,056</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,928</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total lease liability</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">29,128</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>
CY2022Q4 ifrs-full Undiscounted Operating Lease Payments To Be Received
UndiscountedOperatingLeasePaymentsToBeReceived
35056000 usd
CY2022 ptv Interest On Undiscounted Lease Payments
InterestOnUndiscountedLeasePayments
5928000 usd
CY2022Q4 ifrs-full Lease Liabilities
LeaseLiabilities
29128000 usd
CY2022Q4 ifrs-full Current Finance Lease Receivables
CurrentFinanceLeaseReceivables
450000 usd
CY2022Q4 ifrs-full Noncurrent Finance Lease Receivables
NoncurrentFinanceLeaseReceivables
835000 usd
CY2022Q4 ifrs-full Finance Lease Receivables
FinanceLeaseReceivables
1285000 usd
CY2022 ifrs-full Disclosure Of Maturity Analysis Of Finance Lease Payments Receivable Explanatory
DisclosureOfMaturityAnalysisOfFinanceLeasePaymentsReceivableExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The following table details the future maturities of the lease receivable, showing the undiscounted lease payments to be received after the reporting date:</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:87.043%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.757%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="6" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Less than one year</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">513</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">One to two years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">523</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Two to three years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">353</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total undiscounted lease receivable</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,389</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Unearned Finance income</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">103</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Net investment in the lease</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,285</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>
CY2022Q4 ifrs-full Undiscounted Finance Lease Payments To Be Received
UndiscountedFinanceLeasePaymentsToBeReceived
1389000 usd
CY2022Q4 ifrs-full Unearned Finance Income Relating To Finance Lease Payments Receivable
UnearnedFinanceIncomeRelatingToFinanceLeasePaymentsReceivable
103000 usd
CY2022Q4 ifrs-full Net Investment In Finance Lease
NetInvestmentInFinanceLease
1285000 usd
CY2021 ifrs-full Rental Income
RentalIncome
600000 usd
CY2020 ifrs-full Rental Income
RentalIncome
1100000 usd
CY2022 ifrs-full Disclosure Of Financial Risk Management Explanatory
DisclosureOfFinancialRiskManagementExplanatory
Capital and Financial Risk Management <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Capital Risk Management</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group's capital and financial risk management policy is to maintain a strong capital base so as to support its strategic priorities, maintain investor, creditor and market confidence as well as sustain the future development of the business. The Group’s objectives when managing capital are to safeguard its ability to continue as a going concern in order to provide returns for shareholders and benefits for other stakeholders and to maintain an optimal capital structure to reduce the cost of capital. To maintain or adjust the capital structure, the Group may issue new shares or incur new debt. The Group has some external debt and no material externally imposed capital requirements. The Group’s share capital is clearly set out in Note 14.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Management continuously monitors the level of capital deployed and available for deployment in the Internal segment and at the corporate level as well as at Controlled Founded Entities. The Directors seek to maintain a balance between the higher returns that might be possible with higher levels of deployed capital and the advantages and security afforded by a sound capital position.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group’s Directors have overall responsibility for establishment and oversight of the Group's capital and risk management framework. The Group is exposed to certain risks through its normal course of operations. The Group’s main objective in using financial instruments is to promote the development and commercialization of intellectual property through the raising and investing of funds for this purpose. The Group’s policies in calculating the nature, amount and timing of investments are determined by planned future investment activity. Due to the nature of activities and with the aim to maintain the investors’ funds as secure and protected, the Group’s policy is to hold any excess funds in highly liquid and readily available financial instruments and maintain insignificant exposure to other financial risks.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group has exposure to the following risks arising from financial instruments:</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Credit Risk</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Credit risk is the risk of financial loss to the Group if a customer or counterparty to a financial instrument fails to meet its contractual obligations. Financial instruments that potentially subject the Group to concentrations of credit risk consist principally of cash and cash equivalents, short term investments, and trade and other receivables. The Group held the following balances (not including the income tax receivable resulting from overpayment of income taxes, see Note 25):</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and cash equivalents</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">149,866</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">465,708 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">200,229</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,174 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">361,961</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">468,882 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group invests its excess cash in U.S. Treasury Bills (presented as short-term investments), and money market accounts, which the Group believes are of high credit quality. Further the Group's cash and cash equivalents and short-term investments are held at diverse, investment-grade financial institutions.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group assesses the credit quality of customers on an ongoing basis. The credit quality of financial assets is assessed by historical and recent payment history, counterparty financial position, reference to credit ratings (if available) or to historical information about counterparty default rates. The Group does not have expected credit losses owing largely to a small number of counterparties and the high credit quality of most counterparties (primarily the US government and large funds with respect to grant income and large high credit quality corporations).</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The aging of trade and other receivables that were not impaired at December 31 is as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Not impaired</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,174 </span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,174 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">With regard to the Note from associate, such note is presented at fair value which incorporates, among other factors, the credit risk of the counterparty. See Note 16 for details.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Liquidity Risk</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Liquidity risk is the risk that the Group will encounter difficulty in meeting the obligations associated with its financial liabilities that are settled by delivering cash or another financial asset. The Group actively manages its risk of a funds shortage by closely monitoring the maturity of its financial assets and liabilities and projected cash flows from operations, under both normal and stressed conditions, without incurring unacceptable losses or risking damage to the Group’s reputation. Due to the nature of these financial liabilities, the funds are available on demand to provide optimal financial flexibility.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The table below summarizes the maturity profile of the Group’s financial liabilities, including subsidiary preferred shares that have customary liquidation preferences, as of December 31, 2022 and 2021, based on contractual undiscounted payments:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></td></tr><tr style="height:26pt"><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Carrying Amount<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Within Three Months<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Three to Twelve Months<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">One to Five Years<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total<br/>$000s (*)</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term loan (non-current + current)</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15,400</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,838</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,281</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,413</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">18,531</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,345</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,345</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,345</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other payables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">54,840</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">54,840</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">54,840</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrants</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares (Note 15)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,339</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,339</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,339</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99,971</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86,409</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,281</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,413</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">103,103</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td></tr><tr style="height:26pt"><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Carrying Amount<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Within Three Months<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Three to Twelve Months<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">One to Five Years<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s (*)</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term loan</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,118 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">296 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,182 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,274 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,752 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,641 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,641 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,641 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other payables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35,817 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35,817 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35,817 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrants</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,787 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,787 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,787 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares (Note 15)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">174,017 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">174,017 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">174,017 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">236,381 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">221,559 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,182 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,274 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">240,015 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Redeemable only upon a liquidation or Deemed liquidation event, as defined in the applicable shareholder documents.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Warrants issued by subsidiaries to third parties to purchase preferred shares.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">*    Does not include payments in respect of lease obligations. For the contractual future payments related to lease obligations, see Note 21.</span></div><div style="margin-bottom:2pt"><span><br/></span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest Rate Sensitivity </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2022, the Group had cash and cash equivalents of $149.9 million, and short term investments of $200.2 million. The Group's exposure to interest rate sensitivity is impacted by changes in the underlying U.K. and U.S. bank interest rates. The Group has not entered into investments for trading or speculative purposes. Due to the conservative nature of the Group's investment portfolio, which is predicated on capital preservation and investments in short duration, high-quality U.S. Treasury Bills and related money market accounts, a change in interest rates would not have a material effect on the fair market value of the Group's portfolio, and therefore the Group does not expect operating results or cash flows to be significantly affected by changes in market interest rates.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Controlled Founded Entity Investments</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group maintains investments in certain Controlled Founded Entities. The Group’s investments in Controlled Founded Entities are eliminated as intercompany transactions upon financial consolidation. The Group is however exposed to a preferred share liability owing to the terms of existing preferred shares and the ownership of Controlled Founded Entities preferred shares by third parties. As discussed in Note 15, certain of the Group’s subsidiaries have issued preferred shares that include the right to receive a payment in the event of any voluntary or involuntary liquidation, dissolution or winding up of a subsidiary, including in the event of "deemed liquidation" as defined in the incorporation documents of the entities, which shall be paid out of the assets of the subsidiary available for distribution to shareholders and before any payment shall be made to holders of ordinary shares. The liability of preferred shares is maintained at fair value through the profit and loss. The Group’s strong cash position, budgeting and forecasting processes, as well as decision making and risk mitigation framework enable the Group to robustly monitor and support the business activities of the Controlled Founded Entities to ensure no exposure to dissolution or liquidation. Accordingly, the Group views exposure to 3rd party preferred share liability as low.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non-Controlled Founded Entity Investments</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group maintains certain investments in Non-Controlled Founded Entities which are deemed either as investments and accounted for as investments held at fair value or associates and accounted for under the equity method (please refer to Note 1). The Group's exposure to investments held at fair value is $251.9 million as of December 31, 2022, and the Group may or may not be able to realize the value in the future. Accordingly, the Group views the risk as high. The Group’s exposure to investments in associates is limited to the carrying amount of the investment in an Associate. The Group is not exposed to further contractual obligations or contingent liabilities beyond the value of the investments. Accordingly, the Group does not view this as a high risk. As of December 31, 2022, Gelesis and Sonde are the only associates. The carrying amount of the investment in Gelesis and Sonde as associates was $9.1 million. Please refer to Notes 5, 6 and 16 for further information regarding the Group's exposure to Non-Controlled Founded Entity Investments. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Equity Price Risk </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">As of December 31, 2022, the Group held 1,054,464 common shares of Karuna, 2,671,800 common shares of Vor and 12,527,477 common shares of Akili. The fair value of these investments in Karuna, Vor and Akili was $239.0 million.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The investments in Karuna, Vor and Akili are exposed to fluctuations in the market price of these common shares. The effect of a 10.0 percent adverse change in the market price of Karuna, Vor and Akili common shares as of December 31, 2022, would have been a loss of approximately $23.9 million, that would have been recognized as a component of Other income (expense) in the Consolidated Statements of Comprehensive Income/(Loss). </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Foreign Exchange Risk</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group maintains consolidated financial statements in the Group's functional currency, which is the U.S. dollar. Monetary assets and liabilities denominated in currencies other than the functional currency are translated into the functional currency at rates of exchange prevailing at the balance sheet dates. Non-monetary assets and liabilities denominated in foreign currencies are translated into the functional currency at the exchange rates prevailing at the date of the transaction. Exchange gains or losses arising from foreign currency transactions are included in the determination of net income (loss) for the respective periods. Such foreign currency gains or losses were not material for all reported periods. See Note 9.</span></div>The Group does not currently engage in currency hedging activities since its foreign currency risk is limited, but the Group may begin to do so in the future if and when its foreign currency risk exposure changes.
CY2022 ifrs-full Disclosure Of Credit Risk Explanatory
DisclosureOfCreditRiskExplanatory
Financial instruments that potentially subject the Group to concentrations of credit risk consist principally of cash and cash equivalents, short term investments, and trade and other receivables. The Group held the following balances (not including the income tax receivable resulting from overpayment of income taxes, see Note 25):<table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Cash and cash equivalents</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">149,866</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">465,708 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term investments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">200,229</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other receivables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,174 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">361,961</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">468,882 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table>
CY2022Q4 ifrs-full Cash And Cash Equivalents
CashAndCashEquivalents
149866000 usd
CY2021Q4 ifrs-full Cash And Cash Equivalents
CashAndCashEquivalents
465708000 usd
CY2022Q4 ptv Short Term Investments
ShortTermInvestments
200229000 usd
CY2021Q4 ptv Short Term Investments
ShortTermInvestments
0 usd
CY2022Q4 ifrs-full Current Trade Receivables
CurrentTradeReceivables
11867000 usd
CY2021Q4 ifrs-full Current Trade Receivables
CurrentTradeReceivables
3174000 usd
CY2022Q4 ifrs-full Credit Exposure
CreditExposure
361961000 usd
CY2021Q4 ifrs-full Credit Exposure
CreditExposure
468882000 usd
CY2022 ifrs-full Information About Credit Quality Of Neither Past Due Nor Impaired Financial Assets
InformationAboutCreditQualityOfNeitherPastDueNorImpairedFinancialAssets
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The aging of trade and other receivables that were not impaired at December 31 is as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:75.260%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:11pt"><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Not impaired</span></td><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,174 </span></td><td style="border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #001544;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,867</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #001544;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,174 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #001544;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">With regard to the Note from associate, such note is presented at fair value which incorporates, among other factors, the credit risk of the counterparty. See Note 16 for details.</span></div>
CY2022Q4 ifrs-full Current Trade Receivables
CurrentTradeReceivables
11867000 usd
CY2021Q4 ifrs-full Current Trade Receivables
CurrentTradeReceivables
3174000 usd
CY2022 ifrs-full Disclosure Of Liquidity Risk Explanatory
DisclosureOfLiquidityRiskExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The table below summarizes the maturity profile of the Group’s financial liabilities, including subsidiary preferred shares that have customary liquidation preferences, as of December 31, 2022 and 2021, based on contractual undiscounted payments:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></td></tr><tr style="height:26pt"><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Carrying Amount<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Within Three Months<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Three to Twelve Months<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">One to Five Years<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Total<br/>$000s (*)</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term loan (non-current + current)</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">15,400</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,838</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,281</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,413</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">18,531</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,345</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,345</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,345</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other payables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">54,840</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">54,840</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">54,840</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrants</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">47</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares (Note 15)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,339</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,339</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">27,339</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">99,971</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">86,409</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,281</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,413</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">103,103</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:39.802%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.722%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="15" style="padding:2px 1pt;text-align:center;vertical-align:top"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td></tr><tr style="height:26pt"><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Carrying Amount<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Within Three Months<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Three to Twelve Months<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">One to Five Years<br/>$000s</span></div></td><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Total<br/>$000s (*)</span></div></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Long-term loan</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">15,118 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">296 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,182 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,274 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,752 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary notes payable</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,641 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,641 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,641 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and other payables</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35,817 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35,817 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">35,817 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Warrants</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">2</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,787 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,787 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">6,787 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Subsidiary preferred shares (Note 15)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">1</span></div></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">174,017 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">174,017 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">174,017 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">236,381 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">221,559 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,182 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,274 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">240,015 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Redeemable only upon a liquidation or Deemed liquidation event, as defined in the applicable shareholder documents.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Warrants issued by subsidiaries to third parties to purchase preferred shares.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.17pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">*    Does not include payments in respect of lease obligations. For the contractual future payments related to lease obligations, see Note 21.</span></div>
CY2022Q4 ifrs-full Financial Liabilities
FinancialLiabilities
103103000 usd
CY2021Q4 ifrs-full Financial Liabilities
FinancialLiabilities
240015000 usd
CY2022Q4 ifrs-full Cash And Cash Equivalents
CashAndCashEquivalents
149900000 usd
CY2022Q4 ptv Short Term Investments
ShortTermInvestments
200200000 usd
CY2022Q4 ifrs-full Noncurrent Financial Assets At Fair Value Through Profit Or Loss
NoncurrentFinancialAssetsAtFairValueThroughProfitOrLoss
251900000 usd
CY2022 ifrs-full Disclosure Of Commitments And Contingent Liabilities Explanatory
DisclosureOfCommitmentsAndContingentLiabilitiesExplanatory
Commitments and Contingencies <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group is party to certain licensing agreements where the Group is licensing IP from third parties. In consideration for such licenses the Group has made upfront payments and may be required to make additional contingent payments based on developmental and sales milestones and/or royalty on future sales. As of December 31, 2022, these milestone events have not yet occurred and therefore the Group does not have a present obligation to make the related payments in respect of the licenses. Such milestones are dependent on events that are outside of the control of the Group and many of these milestone events are remote of occurring. As of December 31, 2022, payments in respect of developmental milestones that are dependent on events that are outside the control of the Group but are reasonably possible to occur amounted to approximately $8.7 million. These milestone amounts represent an aggregate of multiple milestone payments depending on different milestone events in multiple agreements. The probability that all such milestone events will occur in the aggregate is remote. Payments made to license IP represent the acquisition cost of intangible assets. See Note 12.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group is party to certain sponsored research arrangements as well as arrangements with contract manufacturing and contract research organizations, whereby the counterparty provides the Company with research and/or manufacturing services. As of December 31, 2022, the noncancellable commitments in respect of such contracts amounted to approximately $11.3 million.</span></div>
CY2022Q4 ifrs-full Estimated Financial Effect Of Contingent Liabilities
EstimatedFinancialEffectOfContingentLiabilities
8700000 usd
CY2022Q4 ifrs-full Contractual Capital Commitments
ContractualCapitalCommitments
11300000 usd
CY2022 ifrs-full Disclosure Of Transactions Between Related Parties Explanatory
DisclosureOfTransactionsBetweenRelatedPartiesExplanatory
Related Parties Transactions <div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Related Party Subleases and royalties</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During 2019, PureTech executed a sublease agreement with a related party, Gelesis. Please refer to Note 21 for further details regarding the sublease.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group receives royalties from Gelesis on its product sales. Such royalties amounted to $509 thousand and $231 thousand for the years ended December 31, 2022 and 2021, respectively and are presented in Contract revenue in the Consolidated Statements of Comprehensive Income/(Loss).</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Key Management Personnel Compensation</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Key management includes executive directors and members of the executive management team of the Group (not including compensation provided to non-executive directors). The key management personnel compensation of the Group was as follows for the years ended December 31: </span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:63.330%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term employee benefits</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,369</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,666 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,833 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,741</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,045 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,822 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7,109</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,711 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,656 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term employee benefits include salaries, health care and other non-cash benefits. Share-based payments are generally subject to vesting terms over future periods. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For cash settlements of share based awards – see Note 8.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">In addition the Company paid remuneration to non-executive directors in the amounts of $655 thousand, $605 thousand and $690 thousand for the years ended December 31, 2022, 2021, and 2020, respectively. Also, the Company incurred $365 thousand and $161 thousand of stock based compensation expense for such non-executive directors for the years ended December 31, 2022 and 2021, respectively. There is no stock based compensation expense for such non-executive directors for the year ended December 31, 2020. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">During the years ended December 31, 2022 and 2021, the Company incurred $51 thousand, and $181 thousand, respectively of expenses paid to related parties.</span></div><div><span style="background-color:#ffffff;color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Convertible Notes Issued to Directors</span></div><div style="margin-bottom:5pt"><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Certain related parties of the Group have invested in convertible notes issued by the Group’s subsidiaries. As of </span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">December 31, 2022 and 2021,</span><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> the outstanding related party notes payable</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> totaled $99 thousand and $94 thousand</span><span style="background-color:#ffffff;color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> respectively, including principal and interest. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The notes issued to related parties bear interest rates, maturity dates, discounts and other contractual terms that are the same as those issued to outside investors during the same issuances, as described in Note 17.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Directors’ and Senior Managers’ Shareholdings and Share Incentive Awards</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Directors and senior managers hold beneficial interests in shares in the following businesses and sourcing companies as at December 31, 2022:</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:21.208%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:29.165%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.912%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:11.848%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.912%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:9.355%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Business Name (Share Class)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of shares held as of December 31, 2022</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of options held as of December 31, 2022</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Number of RSUs held as of December 31, 2022</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Ownership<br/>Interest¹</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Directors:</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Ms Daphne Zohar²</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">465,121</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3,303,306</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,349,697</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.45</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Robert Langer</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Entrega (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">250,000</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">82,500</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4.09</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Raju Kucherlapati</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Enlight (Class B Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">30,000</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">139,625</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">50,639</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.12</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr John LaMattina</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Akili (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">56,554</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.07</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis (Common)</span><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:5.52pt;font-weight:400;line-height:120%;position:relative;top:-2.97pt;vertical-align:baseline">3</span></div></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">395,035</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">37,129</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.38</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vedanta Biosciences (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">25,000</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.17</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Senior Managers:</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Bharatt Chowrira</span></td><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Karuna (Common)</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,000</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.01</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Dr Joseph Bolen</span></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Vor (Common)</span></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">9,191</span></td><td colspan="3" style="border-bottom:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span></td><td colspan="2" style="border-bottom:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.01</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">%</span></td></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">1    Ownership interests as of December 31, 2022 are calculated on a diluted basis, including issued and outstanding shares, warrants and options (and written commitments to issue options) but excluding unallocated shares authorized to be issued pursuant to equity incentive plans and any shares issuable upon conversion of outstanding convertible promissory notes.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">2    Common shares, RSUs and options held by Yishai Zohar, who is the husband of Ms. Zohar. Ms. Zohar does not have any direct interest in the share capital of Gelesis. Ms. Zohar recuses herself from any and all material decisions with regard to Gelesis.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:6pt;font-weight:400;line-height:120%">3    Dr John and Ms Mary LaMattina hold 345,035 shares of common shares in Gelesis. Individually, Dr LaMattina holds 50,000 shares of Gelesis and convertible notes issued by Appeering in the aggregate principal amount o $50,000.</span></div><div style="margin-bottom:2pt;padding-left:14.17pt;text-indent:-14.18pt"><span><br/></span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Directors and senior managers hold 25,371,839 ordinary shares and 9.1 percent voting rights of the Company as of December 31, 2022. This amount excludes options to purchase 2,350,000 ordinary shares. This amount also excludes 6,448,899 shares, which are issuable based on the terms of performance based RSU awards granted to certain senior managers covering the financial years 2022, 2021 and 2020, and 172,056 shares, which are issuable to directors immediately prior to the Company's 2023 Annual General Meeting of Stockholders based on the terms of the RSU awards granted to non-executive directors in 2022. Such shares will be issued to such senior managers and non executive directors in future periods provided that </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">performance and/or service conditions are met and certain of the shares will be withheld for payment of customary withholding taxes.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Note from Associate</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">See Note 16 for details on the notes issued by Gelesis to the Company. The Company recognized finance income of 1.6 million with respect to interest and changes in fair value related to the notes. </span></div>As of December 31, 2022 the Group has a receivable from an associate in the amount of 1.1 million
CY2022 ifrs-full Disclosure Of Amounts Incurred By Entity For Provision Of Key Management Personnel Services Provided By Separate Management Entities Explanatory
DisclosureOfAmountsIncurredByEntityForProvisionOfKeyManagementPersonnelServicesProvidedBySeparateManagementEntitiesExplanatory
The key management personnel compensation of the Group was as follows for the years ended December 31: <table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:63.330%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Short-term employee benefits</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">4,369</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,666 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,833 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payment expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,741</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,045 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">5,822 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7,109</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,711 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,656 </span></td><td style="border-bottom:0.5pt solid #000;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table>
CY2022 ifrs-full Key Management Personnel Compensation Shortterm Employee Benefits
KeyManagementPersonnelCompensationShorttermEmployeeBenefits
4369000 usd
CY2021 ifrs-full Key Management Personnel Compensation Shortterm Employee Benefits
KeyManagementPersonnelCompensationShorttermEmployeeBenefits
4666000 usd
CY2020 ifrs-full Key Management Personnel Compensation Shortterm Employee Benefits
KeyManagementPersonnelCompensationShorttermEmployeeBenefits
4833000 usd
CY2022 ifrs-full Key Management Personnel Compensation Sharebased Payment
KeyManagementPersonnelCompensationSharebasedPayment
2741000 usd
CY2021 ifrs-full Key Management Personnel Compensation Sharebased Payment
KeyManagementPersonnelCompensationSharebasedPayment
4045000 usd
CY2020 ifrs-full Key Management Personnel Compensation Sharebased Payment
KeyManagementPersonnelCompensationSharebasedPayment
5822000 usd
CY2022 ifrs-full Key Management Personnel Compensation
KeyManagementPersonnelCompensation
7109000 usd
CY2021 ifrs-full Key Management Personnel Compensation
KeyManagementPersonnelCompensation
8711000 usd
CY2020 ifrs-full Key Management Personnel Compensation
KeyManagementPersonnelCompensation
10656000 usd
CY2022Q4 ifrs-full Trade And Other Receivables Due From Related Parties
TradeAndOtherReceivablesDueFromRelatedParties
1100000 usd
CY2022 ifrs-full Disclosure Of Income Tax Explanatory
DisclosureOfIncomeTaxExplanatory
Taxation <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax on the profit or loss for the year comprises current and deferred income tax. Tax is recognized in the Consolidated Statements of Comprehensive Income/(Loss) except to the extent that it relates to items recognized directly in equity.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">For the years ended December 31, 2022, 2021 and 2020, the Group filed a consolidated U.S. federal income tax return which included all subsidiaries in which the Company owned greater than 80 percent of the vote and value. For the years ended December 31, 2022, 2021 and 2020, the Group filed certain consolidated state income tax returns which included all subsidiaries in which the Company owned greater than 50 percent of the vote and value. The remaining subsidiaries file separate U.S. tax returns.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Amounts recognized in Consolidated Statements of Comprehensive Income/(Loss):</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income/(loss) for the year</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(37,065)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(62,709)</span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,568 </span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income tax expense/(benefit)</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(55,719)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,756 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,401 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Income/(loss) before taxes</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(92,783)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(58,953)</span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">18,969 </span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Recognized income tax expense/(benefit):</span></div><div style="margin-bottom:1pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:63.441%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.721%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Federal</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,065</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,138 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21,796 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Foreign</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">State</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,336</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">109 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total current income tax expense/(benefit)</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">14,401</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">22,247 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21,796 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Federal</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(48,240)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(15,416)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,349)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Foreign</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">State</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(21,880)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,075)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(46)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total deferred income tax expense/(benefit)</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(70,120)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(18,491)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(7,395)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total income tax expense/(benefit), recognized</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(55,719)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,756 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,401 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:112%">The tax expense/(benefit) was $(55.7) million, $3.8 million and $14.4 million in 2022, 2021 and 2020 respectively. The increase in tax benefit for the year ended December 31, 2022 is primarily the result of the loss before taxes in entities in the U.S. Federal and Massachusetts consolidated return groups of the Company. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Reconciliation of Effective Tax Rate</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group is primarily subject to taxation in the U.S. A reconciliation of the U.S. federal statutory tax rate to the effective tax rate is as follows:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:100.000%"><tr><td style="width:1.0%"/><td style="width:26.738%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.422%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.719%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.723%"/><td style="width:0.1%"/></tr><tr><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" style="padding:2px 1pt;text-align:center;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2020</span></td></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">%</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">%</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">%</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">US federal statutory rate</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(19,486)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">21.00</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(12,380)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21.00 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,984 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">21.00 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Effects of state tax rate in U.S.</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(8,043)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8.67</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,484)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7.61 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1,844 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9.72 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">R&amp;D and orphan drug tax credits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(6,876)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7.41</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,056)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8.58 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(5,642)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(29.74)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Non deductible share based payment expenses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">788</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(0.85)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">555 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.94)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">327 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.73 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Finance income/(costs) – fair value accounting</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(28,783)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">31.02</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,017)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3.42 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">919 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.84 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Loss with respect to associate for which no deferred tax asset is recognized</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">1,413</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(1.52)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,542 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(19.58)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Change in blended state rate impact due to state apportionment change</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(8,856)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">9.54</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Transaction Costs</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">309 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.52)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">361 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">1.91 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Interest Expense</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">69</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(0.07)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">217 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.37)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(2,258)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(11.91)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Executive Compensation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">300</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(0.32)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">746 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(1.27)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">827 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4.36 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Recognition of deferred tax assets and tax benefits not previously recognized</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(184)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">0.20</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(414)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.70 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Current year losses for which no deferred tax asset is recognized</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">17,287</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(18.63)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,375 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(24.38)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">13,948 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">73.53 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Sonde Deconsolidation</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,572)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">3.85</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">224</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(0.25)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">363 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(0.62)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">91 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">0.48 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(55,719)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">60.05</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">3,756</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(6.37)</span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:0 1pt"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">14,401</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">75.92 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company is also subject to taxation in the UK but to date no taxable income has been generated in the UK. Changes in corporate tax rates can change both the current tax expense (benefit) as well as the deferred tax expense (benefit). </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred Tax Assets and Liabilities </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets have been recognized in the U.S. jurisdiction in respect of the following items:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:75.187%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.757%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating tax losses</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">48,317</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">46,982 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax credits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,101</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,673 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,423</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,265 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Capitalized Research &amp; Experimental Expenditures</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">36,084</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment in Associates</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,036</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,542 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Lease Liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7,143</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,969 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other temporary differences</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,957</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,665 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">127,061</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">88,096 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(47,877)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(96,804)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">ROU asset</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,519)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,667)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fixed assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,348)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,547)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax liabilities</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(53,744)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(105,018)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets (liabilities), net</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">73,317</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(16,922)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax liabilities, net, recognized</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(19,645)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(89,765)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets (liabilities), net, not recognized</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">92,962</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">72,843 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">We have recognized deferred tax assets related to entities in the U.S. Federal and Massachusetts consolidated return groups due to future reversals of existing taxable temporary differences that will be sufficient to recover the net deferred tax assets. Our unrecognized deferred tax assets of $93.0 million are primarily related to tax credit, loss carryforwards and deductible temporary differences in subsidiaries outside the U.S. Federal and Massachusetts consolidated return groups. Such deferred tax assets have not been recognized because it is not probable that future taxable profits will be available to support their realizability. The unrecognized deferred tax assets, to a lesser extent, also relate to unrecognized deferred tax assets with respect to a portion of Section 174 capitalized research &amp; experimental expenditures which became effective in 2022 under the Tax Cuts and Jobs Act and an investment in an associate since the Group does not believe it is probable that such tax benefits will be realized in the foreseeable future.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">There was movement in deferred tax recognized, which impacted income tax expense by approximately $70.1 million benefit, primarily related to changes in the value of investments and Section 174 capitalized research &amp; experimental expenditures. The Company sold a portion of its stock in Karuna and VOR during 2022 resulting in net taxable income and current tax expense of $14.4 million.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Unrecognized Deferred Tax Assets</span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets have not been recognized in respect of the following carryforward losses, credits and temporary differences, because it is not probable that future taxable profit will be available against which the Group can use the benefits therefrom.</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:50.850%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.424%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="6" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" style="padding:0 1pt"/></tr><tr style="height:9pt"><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Gross Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Tax Effected</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Gross Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Tax Effected</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deductible Temporary Difference</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">132,145</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">33,544</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">59,925 </span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,224 </span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax Losses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">219,466</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">48,317</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">215,425 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">46,982 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax Credits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,101</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,101</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,636 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,636 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">362,712</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">92,962</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">284,986 </span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">72,843 </span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax Losses and tax credits carryforwards </span></div><div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax losses and tax credits for which no deferred tax asset was recognized</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:50.850%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.424%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" rowspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="6" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" style="padding:0 1pt"/></tr><tr style="height:9pt"><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Gross Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Tax Effected</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Gross Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Tax Effected</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax losses expiring:</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Within 10 years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">23,930</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">5,387</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">19,735 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,343 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">More than 10 years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">42,822</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,509</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">47,937 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,611 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Available Indefinitely</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">152,714</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">32,421</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">147,753 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">31,028 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">219,466</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">48,317</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">215,425 </span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">46,982 </span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-top:0.5pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax credits expiring:</span></td><td colspan="3" style="border-top:0.5pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.5pt solid #183964;padding:0 1pt"/><td colspan="3" style="border-top:0.5pt solid #183964;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:0.5pt solid #183964;padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:0.5pt solid #183964;padding:0 1pt"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Within 10 years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">43</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">43</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">More than 10 years</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,058</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,058</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,632 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,632 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Available indefinitely</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">—</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,101</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,101</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,636 </span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,636 </span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group had U.S. federal net operating losses carry forwards (“NOLs”) of approximately $219.5 million, $215.4 million and $169.7 million as of December 31, 2022, 2021 and 2020, respectively, which are available to offset future taxable income. These NOLs expire through 2037 with the exception of $152.7 million which is not subject to expiration. The Group had U.S. Federal research and development tax credits of approximately $4.5 million, $3.9 million and $3.9 million as of December 31, 2022, 2021 and 2020, respectively, which are available to offset future taxes that expire at various dates through 2042. The Group also had Federal Orphan Drug credits of approximately $6.1 million and $5.7 million as of December 31, 2022, and 2021, which are available to offset future taxes that expire at various dates through 2042. A portion of these Federal NOLs and credits can only be used to offset the profits from the Company’s subsidiaries who file separate Federal tax returns. These NOLs and credits are subject to review and possible adjustment by the Internal Revenue Service.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Group had state net operating losses carry forwards (“NOLs”) of approximately $71.7 million, $27.9 million and $67.4 million for the years ended December 31, 2022, 2021 and 2020, respectively, which are available to offset future taxable income. These NOLs expire at various dates beginning in 2030. The Group had Massachusetts research and development tax credits of approximately $0.6 million, $1.3 million and $2.1 million for the years ended December 31, 2022, 2021 and 2020, respectively, which are available to offset future taxes and expire at various dates through 2037. These NOLs and credits are subject to review and possible adjustment by the Massachusetts Department of Revenue. </span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Utilization of the NOLs and research and development credit carryforwards may be subject to a substantial annual limitation under Section 382 of the Internal Revenue Code of 1986 due to ownership change limitations that have occurred previously or that could occur in the future. These ownership changes may limit the amount of NOL and research and development credit carryforwards that can be utilized annually to offset future taxable income and tax, respectively. The Company notes that a 382 analysis was performed through December 31, 2022. The results of this analysis concluded that certain net operating losses were subject to limitation under Section 382 of the Internal Revenue Code. None of the Company’s tax attributes which are subject to a restrictive Section 382 limitation have been recognized in the financial statements. </span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax Balances</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The current tax related balances are presented in the Statement of Financial Position as follows:</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:75.187%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.757%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:11pt"><td colspan="9" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Income tax receivable – current </span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">10,040</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">4,514 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Trade and Other Payables</span></td><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(57)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(57)</span></td><td style="border-bottom:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Uncertain Tax Positions</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company has no uncertain tax positions as of December 31, 2022. U.S. corporations are routinely subject to audit by federal and state tax authorities in the normal course of business.</span></div>
CY2021 ptv Percentage Vote And Value Of Subsidiaries Included In The Group Consolidated Federal Tax Return
PercentageVoteAndValueOfSubsidiariesIncludedInTheGroupConsolidatedFederalTaxReturn
0.80
CY2022 ptv Percentage Vote And Value Of Subsidiaries Included In The Group Consolidated Federal Tax Return
PercentageVoteAndValueOfSubsidiariesIncludedInTheGroupConsolidatedFederalTaxReturn
0.80
CY2020 ptv Percentage Vote And Value Of Subsidiaries In The Group Consolidated State Tax Return
PercentageVoteAndValueOfSubsidiariesInTheGroupConsolidatedStateTaxReturn
0.50
CY2022 ifrs-full Profit Loss
ProfitLoss
-37065000 usd
CY2021 ifrs-full Profit Loss
ProfitLoss
-62709000 usd
CY2020 ifrs-full Profit Loss
ProfitLoss
4568000 usd
CY2022 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
-55719000 usd
CY2021 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
3756000 usd
CY2020 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
14401000 usd
CY2022 ifrs-full Profit Loss Before Tax
ProfitLossBeforeTax
-92783000 usd
CY2021 ifrs-full Profit Loss Before Tax
ProfitLossBeforeTax
-58953000 usd
CY2020 ifrs-full Profit Loss Before Tax
ProfitLossBeforeTax
18969000 usd
CY2022 ifrs-full Current Tax Expense Income
CurrentTaxExpenseIncome
14401000 usd
CY2021 ifrs-full Current Tax Expense Income
CurrentTaxExpenseIncome
22247000 usd
CY2020 ifrs-full Current Tax Expense Income
CurrentTaxExpenseIncome
21796000 usd
CY2022 ifrs-full Deferred Tax Expense Income
DeferredTaxExpenseIncome
-70120000 usd
CY2021 ifrs-full Deferred Tax Expense Income
DeferredTaxExpenseIncome
-18491000 usd
CY2020 ifrs-full Deferred Tax Expense Income
DeferredTaxExpenseIncome
-7395000 usd
CY2022 ifrs-full Deferred Tax Expense Income Recognised In Profit Or Loss
DeferredTaxExpenseIncomeRecognisedInProfitOrLoss
-55719000 usd
CY2021 ifrs-full Deferred Tax Expense Income Recognised In Profit Or Loss
DeferredTaxExpenseIncomeRecognisedInProfitOrLoss
3756000 usd
CY2020 ifrs-full Deferred Tax Expense Income Recognised In Profit Or Loss
DeferredTaxExpenseIncomeRecognisedInProfitOrLoss
14401000 usd
CY2022 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
-55700000 usd
CY2021 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
3800000 usd
CY2020 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
14400000 usd
CY2022 ifrs-full Tax Expense Income At Applicable Tax Rate
TaxExpenseIncomeAtApplicableTaxRate
-19486000 usd
CY2022 ifrs-full Applicable Tax Rate
ApplicableTaxRate
0.2100
CY2021 ifrs-full Tax Expense Income At Applicable Tax Rate
TaxExpenseIncomeAtApplicableTaxRate
-12380000 usd
CY2021 ifrs-full Applicable Tax Rate
ApplicableTaxRate
0.2100
CY2020 ifrs-full Tax Expense Income At Applicable Tax Rate
TaxExpenseIncomeAtApplicableTaxRate
3984000 usd
CY2020 ifrs-full Applicable Tax Rate
ApplicableTaxRate
0.2100
CY2022 ptv Effects Of State Tax Rate In Us Reconciliation Of Effective Tax Rate
EffectsOfStateTaxRateInUSReconciliationOfEffectiveTaxRate
-8043000 usd
CY2022 ptv Rate Of Effects Of State Tax Rate In Us
RateOfEffectsOfStateTaxRateInUS
0.0867
CY2021 ptv Effects Of State Tax Rate In Us Reconciliation Of Effective Tax Rate
EffectsOfStateTaxRateInUSReconciliationOfEffectiveTaxRate
-4484000 usd
CY2021 ptv Rate Of Effects Of State Tax Rate In Us
RateOfEffectsOfStateTaxRateInUS
0.0761
CY2020 ptv Effects Of State Tax Rate In Us Reconciliation Of Effective Tax Rate
EffectsOfStateTaxRateInUSReconciliationOfEffectiveTaxRate
1844000 usd
CY2020 ptv Rate Of Effects Of State Tax Rate In Us
RateOfEffectsOfStateTaxRateInUS
0.0972
CY2022 ptv Research And Development And Orphan Drug Tax Credits Reconciliation Of Effective Tax Rate
ResearchAndDevelopmentAndOrphanDrugTaxCreditsReconciliationOfEffectiveTaxRate
6876000 usd
CY2022 ptv Rate Of Research And Development And Orphan Drug Tax Credits Reconciliation Of Effective Tax Rate
RateOfResearchAndDevelopmentAndOrphanDrugTaxCreditsReconciliationOfEffectiveTaxRate
-0.0741
CY2021 ptv Research And Development And Orphan Drug Tax Credits Reconciliation Of Effective Tax Rate
ResearchAndDevelopmentAndOrphanDrugTaxCreditsReconciliationOfEffectiveTaxRate
5056000 usd
CY2021 ptv Rate Of Research And Development And Orphan Drug Tax Credits Reconciliation Of Effective Tax Rate
RateOfResearchAndDevelopmentAndOrphanDrugTaxCreditsReconciliationOfEffectiveTaxRate
-0.0858
CY2020 ptv Research And Development And Orphan Drug Tax Credits Reconciliation Of Effective Tax Rate
ResearchAndDevelopmentAndOrphanDrugTaxCreditsReconciliationOfEffectiveTaxRate
5642000 usd
CY2020 ptv Rate Of Research And Development And Orphan Drug Tax Credits Reconciliation Of Effective Tax Rate
RateOfResearchAndDevelopmentAndOrphanDrugTaxCreditsReconciliationOfEffectiveTaxRate
0.2974
CY2022 ptv Share Based Payment Expenses Non Deductible Reconciliation Of Effective Tax Rate
ShareBasedPaymentExpensesNonDeductibleReconciliationOfEffectiveTaxRate
788000 usd
CY2022 ptv Rate Of Share Based Payment Expenses Non Deductible Reconciliation Of Effective Tax Rate
RateOfShareBasedPaymentExpensesNonDeductibleReconciliationOfEffectiveTaxRate
-0.0085
CY2021 ptv Share Based Payment Expenses Non Deductible Reconciliation Of Effective Tax Rate
ShareBasedPaymentExpensesNonDeductibleReconciliationOfEffectiveTaxRate
555000 usd
CY2021 ptv Rate Of Share Based Payment Expenses Non Deductible Reconciliation Of Effective Tax Rate
RateOfShareBasedPaymentExpensesNonDeductibleReconciliationOfEffectiveTaxRate
-0.0094
CY2020 ptv Share Based Payment Expenses Non Deductible Reconciliation Of Effective Tax Rate
ShareBasedPaymentExpensesNonDeductibleReconciliationOfEffectiveTaxRate
327000 usd
CY2020 ptv Rate Of Share Based Payment Expenses Non Deductible Reconciliation Of Effective Tax Rate
RateOfShareBasedPaymentExpensesNonDeductibleReconciliationOfEffectiveTaxRate
0.0173
CY2022 ptv Finance Income Costs Fair Value Accounting Reconciliation Of Effective Tax Rate
FinanceIncomeCostsFairValueAccountingReconciliationOfEffectiveTaxRate
-28783000 usd
CY2022 ptv Rate Of Finance Income Costs Fair Value Accounting Reconciliation Of Effective Tax Rate
RateOfFinanceIncomeCostsFairValueAccountingReconciliationOfEffectiveTaxRate
0.3102
CY2021 ptv Finance Income Costs Fair Value Accounting Reconciliation Of Effective Tax Rate
FinanceIncomeCostsFairValueAccountingReconciliationOfEffectiveTaxRate
-2017000 usd
CY2021 ptv Rate Of Finance Income Costs Fair Value Accounting Reconciliation Of Effective Tax Rate
RateOfFinanceIncomeCostsFairValueAccountingReconciliationOfEffectiveTaxRate
0.0342
CY2020 ptv Finance Income Costs Fair Value Accounting Reconciliation Of Effective Tax Rate
FinanceIncomeCostsFairValueAccountingReconciliationOfEffectiveTaxRate
919000 usd
CY2020 ptv Rate Of Finance Income Costs Fair Value Accounting Reconciliation Of Effective Tax Rate
RateOfFinanceIncomeCostsFairValueAccountingReconciliationOfEffectiveTaxRate
0.0484
CY2022 ptv Loss With Respect To Associate For Which No Deferred Tax Asset Is Recognized Reconciliation Of Effective Tax Rate
LossWithRespectToAssociateForWhichNoDeferredTaxAssetIsRecognizedReconciliationOfEffectiveTaxRate
1413000 usd
CY2022 ptv Rate Of Loss With Respect To Associate For Which No Deferred Tax Asset Is Recognized Reconciliation Of Effective Tax Rate
RateOfLossWithRespectToAssociateForWhichNoDeferredTaxAssetIsRecognizedReconciliationOfEffectiveTaxRate
-0.0152
CY2021 ptv Loss With Respect To Associate For Which No Deferred Tax Asset Is Recognized Reconciliation Of Effective Tax Rate
LossWithRespectToAssociateForWhichNoDeferredTaxAssetIsRecognizedReconciliationOfEffectiveTaxRate
11542000 usd
CY2021 ptv Rate Of Loss With Respect To Associate For Which No Deferred Tax Asset Is Recognized Reconciliation Of Effective Tax Rate
RateOfLossWithRespectToAssociateForWhichNoDeferredTaxAssetIsRecognizedReconciliationOfEffectiveTaxRate
-0.1958
CY2020 ptv Loss With Respect To Associate For Which No Deferred Tax Asset Is Recognized Reconciliation Of Effective Tax Rate
LossWithRespectToAssociateForWhichNoDeferredTaxAssetIsRecognizedReconciliationOfEffectiveTaxRate
0 usd
CY2020 ptv Rate Of Loss With Respect To Associate For Which No Deferred Tax Asset Is Recognized Reconciliation Of Effective Tax Rate
RateOfLossWithRespectToAssociateForWhichNoDeferredTaxAssetIsRecognizedReconciliationOfEffectiveTaxRate
0
CY2022 ptv Adjustments Related To Change In Blend State Rate
AdjustmentsRelatedToChangeInBlendStateRate
-8856000 usd
CY2022 ptv Tax Rate Effect Of Adjustments Related To Change In Blend State Rate
TaxRateEffectOfAdjustmentsRelatedToChangeInBlendStateRate
0.0954
CY2021 ptv Adjustments Related To Change In Blend State Rate
AdjustmentsRelatedToChangeInBlendStateRate
0 usd
CY2021 ptv Tax Rate Effect Of Adjustments Related To Change In Blend State Rate
TaxRateEffectOfAdjustmentsRelatedToChangeInBlendStateRate
0
CY2020 ptv Adjustments Related To Change In Blend State Rate
AdjustmentsRelatedToChangeInBlendStateRate
0 usd
CY2020 ptv Tax Rate Effect Of Adjustments Related To Change In Blend State Rate
TaxRateEffectOfAdjustmentsRelatedToChangeInBlendStateRate
0
CY2022 ptv Transaction Costs Reconciliation Of Effective Tax Rate
TransactionCostsReconciliationOfEffectiveTaxRate
0 usd
CY2022 ptv Rate Of Transaction Costs Reconciliation Of Effective Tax Rate
RateOfTransactionCostsReconciliationOfEffectiveTaxRate
0
CY2021 ptv Transaction Costs Reconciliation Of Effective Tax Rate
TransactionCostsReconciliationOfEffectiveTaxRate
309000 usd
CY2021 ptv Rate Of Transaction Costs Reconciliation Of Effective Tax Rate
RateOfTransactionCostsReconciliationOfEffectiveTaxRate
-0.0052
CY2020 ptv Transaction Costs Reconciliation Of Effective Tax Rate
TransactionCostsReconciliationOfEffectiveTaxRate
361000 usd
CY2020 ptv Rate Of Transaction Costs Reconciliation Of Effective Tax Rate
RateOfTransactionCostsReconciliationOfEffectiveTaxRate
0.0191
CY2022 ptv Interest Expense Reconciliation Of Effective Tax Rate
InterestExpenseReconciliationOfEffectiveTaxRate
69000 usd
CY2022 ptv Rate Of Interest Expense Reconciliation Of Effective Tax Rate
RateOfInterestExpenseReconciliationOfEffectiveTaxRate
-0.0007
CY2021 ptv Interest Expense Reconciliation Of Effective Tax Rate
InterestExpenseReconciliationOfEffectiveTaxRate
217000 usd
CY2021 ptv Rate Of Interest Expense Reconciliation Of Effective Tax Rate
RateOfInterestExpenseReconciliationOfEffectiveTaxRate
-0.0037
CY2020 ptv Interest Expense Reconciliation Of Effective Tax Rate
InterestExpenseReconciliationOfEffectiveTaxRate
-2258000 usd
CY2020 ptv Rate Of Interest Expense Reconciliation Of Effective Tax Rate
RateOfInterestExpenseReconciliationOfEffectiveTaxRate
-0.1191
CY2022 ptv Executive Compensation Reconciliation Of Effective Tax Rate
ExecutiveCompensationReconciliationOfEffectiveTaxRate
300000 usd
CY2022 ptv Rate Of Executive Compensation Reconciliation Of Effective Tax Rate
RateOfExecutiveCompensationReconciliationOfEffectiveTaxRate
-0.0032
CY2021 ptv Executive Compensation Reconciliation Of Effective Tax Rate
ExecutiveCompensationReconciliationOfEffectiveTaxRate
746000 usd
CY2021 ptv Rate Of Executive Compensation Reconciliation Of Effective Tax Rate
RateOfExecutiveCompensationReconciliationOfEffectiveTaxRate
-0.0127
CY2020 ptv Executive Compensation Reconciliation Of Effective Tax Rate
ExecutiveCompensationReconciliationOfEffectiveTaxRate
827000 usd
CY2020 ptv Rate Of Executive Compensation Reconciliation Of Effective Tax Rate
RateOfExecutiveCompensationReconciliationOfEffectiveTaxRate
0.0436
CY2022 ptv Deferred Tax Assets And Benefits Not Previously Recognised Reconciliation Of Effective Tax Rate
DeferredTaxAssetsAndBenefitsNotPreviouslyRecognisedReconciliationOfEffectiveTaxRate
184000 usd
CY2022 ptv Tax Rate Effect Of Deferred Tax Assets And Benefits Not Previously Recognised
TaxRateEffectOfDeferredTaxAssetsAndBenefitsNotPreviouslyRecognised
-0.0020
CY2021 ptv Deferred Tax Assets And Benefits Not Previously Recognised Reconciliation Of Effective Tax Rate
DeferredTaxAssetsAndBenefitsNotPreviouslyRecognisedReconciliationOfEffectiveTaxRate
414000 usd
CY2021 ptv Tax Rate Effect Of Deferred Tax Assets And Benefits Not Previously Recognised
TaxRateEffectOfDeferredTaxAssetsAndBenefitsNotPreviouslyRecognised
-0.0070
CY2020 ptv Deferred Tax Assets And Benefits Not Previously Recognised Reconciliation Of Effective Tax Rate
DeferredTaxAssetsAndBenefitsNotPreviouslyRecognisedReconciliationOfEffectiveTaxRate
0 usd
CY2020 ptv Tax Rate Effect Of Deferred Tax Assets And Benefits Not Previously Recognised
TaxRateEffectOfDeferredTaxAssetsAndBenefitsNotPreviouslyRecognised
0
CY2022 ifrs-full Tax Effect Of Tax Losses
TaxEffectOfTaxLosses
17287000 usd
CY2022 ifrs-full Tax Rate Effect Of Tax Losses
TaxRateEffectOfTaxLosses
-0.1863
CY2021 ifrs-full Tax Effect Of Tax Losses
TaxEffectOfTaxLosses
14375000 usd
CY2021 ifrs-full Tax Rate Effect Of Tax Losses
TaxRateEffectOfTaxLosses
-0.2438
CY2020 ifrs-full Tax Effect Of Tax Losses
TaxEffectOfTaxLosses
13948000 usd
CY2020 ifrs-full Tax Rate Effect Of Tax Losses
TaxRateEffectOfTaxLosses
0.7353
CY2022 ptv Deconsolidation Adjustments Reconciliation Of Effective Tax Rate
DeconsolidationAdjustmentsReconciliationOfEffectiveTaxRate
3572000 usd
CY2022 ptv Rate Of Deconsolidation Adjustments Reconciliation Of Effective Tax Rate
RateOfDeconsolidationAdjustmentsReconciliationOfEffectiveTaxRate
-0.0385
CY2021 ptv Deconsolidation Adjustments Reconciliation Of Effective Tax Rate
DeconsolidationAdjustmentsReconciliationOfEffectiveTaxRate
0 usd
CY2021 ptv Rate Of Deconsolidation Adjustments Reconciliation Of Effective Tax Rate
RateOfDeconsolidationAdjustmentsReconciliationOfEffectiveTaxRate
0
CY2020 ptv Deconsolidation Adjustments Reconciliation Of Effective Tax Rate
DeconsolidationAdjustmentsReconciliationOfEffectiveTaxRate
0 usd
CY2020 ptv Rate Of Deconsolidation Adjustments Reconciliation Of Effective Tax Rate
RateOfDeconsolidationAdjustmentsReconciliationOfEffectiveTaxRate
0
CY2022 ifrs-full Other Tax Effects For Reconciliation Between Accounting Profit And Tax Expense Income
OtherTaxEffectsForReconciliationBetweenAccountingProfitAndTaxExpenseIncome
224000 usd
CY2022 ifrs-full Other Tax Rate Effects For Reconciliation Between Accounting Profit And Tax Expense Income
OtherTaxRateEffectsForReconciliationBetweenAccountingProfitAndTaxExpenseIncome
-0.0025
CY2021 ifrs-full Other Tax Effects For Reconciliation Between Accounting Profit And Tax Expense Income
OtherTaxEffectsForReconciliationBetweenAccountingProfitAndTaxExpenseIncome
363000 usd
CY2021 ifrs-full Other Tax Rate Effects For Reconciliation Between Accounting Profit And Tax Expense Income
OtherTaxRateEffectsForReconciliationBetweenAccountingProfitAndTaxExpenseIncome
-0.0062
CY2020 ifrs-full Other Tax Effects For Reconciliation Between Accounting Profit And Tax Expense Income
OtherTaxEffectsForReconciliationBetweenAccountingProfitAndTaxExpenseIncome
91000 usd
CY2020 ifrs-full Other Tax Rate Effects For Reconciliation Between Accounting Profit And Tax Expense Income
OtherTaxRateEffectsForReconciliationBetweenAccountingProfitAndTaxExpenseIncome
0.0048
CY2022 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
-55719000 usd
CY2022 ifrs-full Average Effective Tax Rate
AverageEffectiveTaxRate
0.6005
CY2021 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
3756000 usd
CY2021 ifrs-full Average Effective Tax Rate
AverageEffectiveTaxRate
-0.0637
CY2020 ifrs-full Income Tax Expense Continuing Operations
IncomeTaxExpenseContinuingOperations
14401000 usd
CY2020 ifrs-full Average Effective Tax Rate
AverageEffectiveTaxRate
0.7592
CY2022 ifrs-full Disclosure Of Deferred Taxes Explanatory
DisclosureOfDeferredTaxesExplanatory
<div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets have been recognized in the U.S. jurisdiction in respect of the following items:</span></div><div style="margin-bottom:5.25pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:75.187%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.757%"/><td style="width:0.1%"/><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:right"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:right"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td><td colspan="3" style="display:none"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #000;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Operating tax losses</span></td><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">48,317</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #000;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">46,982 </span></td><td style="border-top:0.25pt solid #000;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax credits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,101</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">10,673 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Share-based payments</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">8,423</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">7,265 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Capitalized Research &amp; Experimental Expenditures</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">36,084</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">— </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investment in Associates</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">13,036</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">11,542 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Lease Liability</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">7,143</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">8,969 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Other temporary differences</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">2,957</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">2,665 </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">127,061</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">88,096 </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Investments held at fair value</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(47,877)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(96,804)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">ROU asset</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(3,519)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(4,667)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Fixed assets</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(2,348)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(3,547)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax liabilities</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(53,744)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(105,018)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets (liabilities), net</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">73,317</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(16,922)</span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax liabilities, net, recognized</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">(19,645)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">(89,765)</span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/><td colspan="3" style="display:none"/></tr><tr><td colspan="3" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets (liabilities), net, not recognized</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">92,962</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">72,843 </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="display:none"/></tr></table></div>
CY2022 ifrs-full Deferred Tax Expense Income
DeferredTaxExpenseIncome
-70100000 usd
CY2022 ifrs-full Current Tax Expense Income
CurrentTaxExpenseIncome
14400000 usd
CY2022 ifrs-full Disclosure Of Temporary Difference Unused Tax Losses And Unused Tax Credits Explanatory
DisclosureOfTemporaryDifferenceUnusedTaxLossesAndUnusedTaxCreditsExplanatory
<div><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deferred tax assets have not been recognized in respect of the following carryforward losses, credits and temporary differences, because it is not probable that future taxable profit will be available against which the Group can use the benefits therefrom.</span></div><div style="margin-bottom:5pt"><table style="border-collapse:collapse;display:inline-table;margin-bottom:5pt;vertical-align:text-bottom;width:99.877%"><tr><td style="width:1.0%"/><td style="width:50.850%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:0.1%"/><td style="width:0.424%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.756%"/><td style="width:0.1%"/><td style="width:1.0%"/><td style="width:10.758%"/><td style="width:0.1%"/></tr><tr style="height:9pt"><td colspan="3" style="background-color:#ffffff;padding:0 1pt"/><td colspan="6" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">2022</span></div><div style="text-align:center"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">$000s</span></div></td><td colspan="3" style="padding:0 1pt"/><td colspan="6" rowspan="2" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">2021</span></div><div style="text-align:center"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">$000s</span></div></td></tr><tr style="height:9pt"><td colspan="3" rowspan="2" style="background-color:#ffffff;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">As of December 31</span></td><td colspan="3" style="padding:0 1pt"/></tr><tr style="height:9pt"><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Gross Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:7pt;font-weight:700;line-height:120%">Tax Effected</span></td><td colspan="3" style="padding:0 1pt"/><td colspan="3" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Gross Amount</span></td><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:7pt;font-weight:400;line-height:120%">Tax Effected</span></td></tr><tr><td colspan="3" style="border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Deductible Temporary Difference</span></td><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">132,145</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">33,544</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">59,925 </span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">16,224 </span></td><td style="background-color:#ffffff;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax Losses</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">219,466</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">48,317</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">215,425 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">46,982 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Tax Credits</span></td><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,101</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">11,101</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,636 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">9,636 </span></td><td style="background-color:#ffffff;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr><tr><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt;text-align:left;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Total</span></td><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">362,712</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:700;line-height:120%">92,962</span><span style="color:#000000;font-family:'Avenir LT Pro 85 Heavy',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%"> </span></td><td style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="3" style="border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:0 1pt"/><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">284,986 </span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/><td colspan="2" style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 0 2px 1pt;text-align:right;vertical-align:bottom"><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">72,843 </span></td><td style="background-color:#ffffff;border-bottom:0.5pt solid #183964;border-top:0.25pt solid #183964;padding:2px 1pt 2px 0;text-align:right;vertical-align:bottom"/></tr></table></div>
CY2022Q4 ptv Trade Receivables Income Tax Receivable
TradeReceivablesIncomeTaxReceivable
10040000 usd
CY2021Q4 ptv Trade Receivables Income Tax Receivable
TradeReceivablesIncomeTaxReceivable
4514000 usd
CY2022Q4 ptv Trade Payables Income Tax Payable
TradePayablesIncomeTaxPayable
57000 usd
CY2021Q4 ptv Trade Payables Income Tax Payable
TradePayablesIncomeTaxPayable
57000 usd
CY2022 ifrs-full Disclosure Of Events After Reporting Period Explanatory
DisclosureOfEventsAfterReportingPeriodExplanatory
Subsequent Events <div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">The Company has evaluated subsequent events after December 31, 2022, the date of issuance of the Consolidated Financial Statements, and has not identified any recordable or disclosable events not otherwise reported in these Consolidated Financial Statements or notes thereto, except for the following:</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On March 1, 2023 Vedanta issued convertible debt to a syndicate of investors. The initial close of the debt was for proceeds of approximately $88.5 million. The note carries an interest rate of 9 percent per annum. The debt has various conversion triggers and the conversion price is established at the lower of 80% of the equity price of the last financing round, or a certain pre-money valuation cap established in the agreement. As part of the issuance of the debt, the convertible debt holders were granted representation in Vedanta's Board of Directors and PureTech lost control over Vedanta. On April 24, 2023, Vedanta closed the second tranche of the convertible debt for additional proceeds of $18.0 million, of which $5.0 million were invested by the Company.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On March 22, 2023, the Company entered into an agreement with Royalty Pharma according to which Royalty Pharma acquired an interset in the Group's royalty from Karuna's KarXT, with $100.0 million in cash up-front, and up to $400.0 million in additional cash consideration, contingent on the achievement of certain regulatory and commercial milestones.</span></div><div><span style="color:#183964;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">Gelesis</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On February 21, 2023, the Company entered into a Note and Warrant Purchase agreement with Gelesis for $5.0 million cash consideration. As part of the agreement, the Company received a short term convertible senior secured note of $5.0 million and warrants to purchase additional shares of Gelesis' common stock. The note carries an interest rate of 12 percent per annum and holds an initial maturity date of July 31, 2023 unless the note is earlier converted or redeemed by the issuer.</span></div><div style="margin-bottom:5pt"><span style="color:#000000;font-family:'Avenir LT Pro 45 Book',sans-serif;font-size:8.5pt;font-weight:400;line-height:120%">On April 10, 2023, the NYSE commenced proceedings to delist the common stock of Gelesis from the NYSE due to Gelesis ceasing to meet certain conditions to trade on such stock exchange. Trading in the Gelesis’s common stock was suspended immediately, and it was subsequently delisted from the NYSE. The common stock of Gelesis is currently available for trading in the over-the-counter (“OTC”) market under the symbol GLSH. </span></div>In addition, in April 2023 PureTech submitted a non-binding proposal to acquire all of the outstanding equity of Gelesis. Negotiations related to the proposal and any potential deal remain ongoing and are subject to, among other things, approval of any definitive transaction by independent committees of the boards of both Gelesis and PureTech.

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