$RGLS
Regulus Therapeutics Inc. Stock $rgls

$rgls Overview Financials Valuation SEC Filings Company Website

2019 Q1 Form 10-K Financial Statement

#000162828019003037 Filed on March 18, 2019

Income Statement

Concept	2019 Q1	2017 Q4	2017 Q3
Revenue	$6.778M	$18.00K	$18.00K
YoY Change	37555.56%	0.0%	-91.18%
Cost Of Revenue
YoY Change
Gross Profit
YoY Change
Gross Profit Margin
Selling, General & Admin	$3.530M	$3.260M	$2.740M
YoY Change	-6.37%	-31.8%	-43.39%
% of Gross Profit
Research & Development	$5.983M	$10.47M	$12.70M
YoY Change	-49.42%	-30.11%	-12.76%
% of Gross Profit
Depreciation & Amortization	$502.0K	$580.0K	$580.0K
YoY Change	-10.83%	-15.94%	-12.12%
% of Gross Profit
Operating Expenses	$9.516M	$13.72M	$15.43M
YoY Change	-39.0%	-30.55%	-20.43%
Operating Profit	-$2.738M		-$15.42M
YoY Change	-82.43%		-19.68%
Interest Expense	$578.0K	-$800.0K	$580.0K
YoY Change	-4.46%	196.3%	3.57%
% of Operating Profit
Other Income/Expense, Net
YoY Change
Pretax Income	-$3.260M	-$14.51M	-$15.84M
YoY Change	-79.66%	-27.52%	-18.86%
Income Tax	$0.00	-$36.31M	-$7.000K
% Of Pretax Income
Net Earnings	-$3.260M	-$14.45M	-$15.83M
YoY Change	-79.66%	-27.83%	-18.91%
Net Earnings / Revenue	-48.1%	-80266.67%	-87933.33%
Basic Earnings Per Share
Diluted Earnings Per Share	-$314.1K	-$1.663M	-$2.108M
COMMON SHARES
Basic Shares Outstanding	10.74M shares	104.0M shares	103.8M shares
Diluted Shares Outstanding

Balance Sheet

Concept	2019 Q1	2017 Q4	2017 Q3
SHORT-TERM ASSETS
Cash & Short-Term Investments	$10.30M	$60.10M	$71.40M
YoY Change	-77.16%	-21.02%	-22.05%
Cash & Equivalents	$10.32M	$13.52M	$20.22M
Short-Term Investments		$46.60M	$51.10M
Other Short-Term Assets	$801.0K	$1.506M	$1.752M
YoY Change	-44.8%	-63.75%	556.18%
Inventory
Prepaid Expenses	$3.826M	$4.783M	$5.912M
Receivables	$2.800M	$400.0K	$500.0K
Other Receivables	$0.00	$0.00	$0.00
Total Short-Term Assets	$17.74M	$66.74M	$79.57M
YoY Change	-65.51%	-23.71%	-22.62%
LONG-TERM ASSETS
Property, Plant & Equipment	$1.598M	$9.708M	$10.17M
YoY Change	-82.83%	-17.94%	-15.53%
Goodwill
YoY Change
Intangibles	$407.0K	$775.0K	$802.0K
YoY Change	-43.94%	-23.65%	-23.69%
Long-Term Investments
YoY Change
Other Assets	$133.0K	$590.0K	$307.0K
YoY Change	-78.55%	72.51%	-10.5%
Total Long-Term Assets	$2.138M	$11.07M	$11.28M
YoY Change	-79.93%	-16.03%	-16.04%
TOTAL ASSETS
Total Short-Term Assets	$17.74M	$66.74M	$79.57M
Total Long-Term Assets	$2.138M	$11.07M	$11.28M
Total Assets	$19.88M	$77.81M	$90.85M
YoY Change	-67.98%	-22.7%	-21.86%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable	$2.650M	$5.743M	$5.229M
YoY Change	-39.72%	-1.66%	-8.65%
Accrued Expenses	$1.745M	$4.941M	$4.770M
YoY Change	-48.23%	-11.4%	-5.84%
Deferred Revenue	$60.00K	$72.00K
YoY Change
Short-Term Debt	$0.00	$0.00	$0.00
YoY Change
Long-Term Debt Due	$15.50M	$19.90M
YoY Change	-22.11%
Total Short-Term Liabilities	$24.84M	$32.60M	$11.76M
YoY Change	-19.7%	136.11%	-10.6%
LONG-TERM LIABILITIES
Long-Term Debt	$200.0K	$0.00	$19.80M
YoY Change		-100.0%	0.0%
Other Long-Term Liabilities	$1.106M	$0.00	$351.0K
YoY Change	152.51%	-100.0%	-95.93%
Total Long-Term Liabilities	$1.106M	$0.00	$351.0K
YoY Change	152.51%	-100.0%	-95.93%
TOTAL LIABILITIES
Total Short-Term Liabilities	$24.84M	$32.60M	$11.76M
Total Long-Term Liabilities	$1.106M	$0.00	$351.0K
Total Liabilities	$25.95M	$42.59M	$42.27M
YoY Change	-33.82%	-4.47%	-3.02%
SHAREHOLDERS EQUITY
Retained Earnings	-$396.0M	-$345.9M	-$331.4M
YoY Change	15.11%	26.53%	30.82%
Common Stock	$389.9M	$381.2M	$380.1M
YoY Change	1.79%	15.68%	16.55%
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity	-$6.069M	$35.22M	$48.58M
YoY Change
Total Liabilities & Shareholders Equity	$19.88M	$77.81M	$90.85M
YoY Change	-67.98%	-22.7%	-21.86%

Cashflow Statement

Concept	2019 Q1	2017 Q4	2017 Q3
OPERATING ACTIVITIES
Net Income	-$3.260M	-$14.45M	-$15.83M
YoY Change	-79.66%	-27.83%	-18.91%
Depreciation, Depletion And Amortization	$502.0K	$580.0K	$580.0K
YoY Change	-10.83%	-15.94%	-12.12%
Cash From Operating Activities	-$4.433M	-$11.10M	-$11.66M
YoY Change	-71.59%	-26.49%	-24.77%
INVESTING ACTIVITIES
Capital Expenditures		-$80.00K	-$100.0K
YoY Change		-50.0%	-79.17%
Acquisitions
YoY Change
Other Investing Activities	$160.0K	$4.480M	-$23.70M
YoY Change	-98.6%	-71.19%	-795.01%
Cash From Investing Activities	$161.0K	$4.400M	-$23.80M
YoY Change	-98.59%	-71.39%	-909.52%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net	$2.086M
YoY Change	902.88%
Debt Paid & Issued, Net
YoY Change
Cash From Financing Activities	$657.0K	0.000	43.15M
YoY Change	-6.28%	-100.0%	18660.87%
NET CHANGE
Cash From Operating Activities	-$4.433M	-11.10M	-11.66M
Cash From Investing Activities	$161.0K	4.400M	-23.80M
Cash From Financing Activities	$657.0K	0.000	43.15M
Net Change In Cash	-$3.615M	-6.700M	7.690M
YoY Change	4.42%	-2891.67%	-162.37%
FREE CASH FLOW
Cash From Operating Activities	-$4.433M	-$11.10M	-$11.66M
Capital Expenditures		-$80.00K	-$100.0K
Free Cash Flow		-$11.02M	-$11.56M
YoY Change		-26.24%	-23.04%

Facts In Submission

Frame	Concept Type	Concept / XBRL Key	Value	Unit
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CY2018	dei	Entity Current Reporting Status EntityCurrentReportingStatus	Yes
CY2018	dei	Entity Emerging Growth Company EntityEmergingGrowthCompany	false
CY2018	dei	Entity Filer Category EntityFilerCategory	Accelerated Filer
CY2018Q2	dei	Entity Public Float EntityPublicFloat	66800000	USD
CY2018	dei	Entity Registrant Name EntityRegistrantName	REGULUS THERAPEUTICS INC.
CY2018	dei	Entity Shell Company EntityShellCompany	false
CY2018	dei	Entity Small Business EntitySmallBusiness	true
CY2018	dei	Entity Voluntary Filers EntityVoluntaryFilers	No
CY2018	dei	Amendment Flag AmendmentFlag	false
CY2018	dei	Current Fiscal Year End Date CurrentFiscalYearEndDate	--12-31
CY2018	dei	Document Fiscal Period Focus DocumentFiscalPeriodFocus	FY
CY2018	dei	Document Fiscal Year Focus DocumentFiscalYearFocus	2018
CY2018	dei	Document Period End Date DocumentPeriodEndDate	2018-12-31
CY2018	dei	Document Type DocumentType	10-K
CY2018	dei	Entity Central Index Key EntityCentralIndexKey	0001505512
CY2018	dei	Entity Well Known Seasoned Issuer EntityWellKnownSeasonedIssuer	No
CY2018	dei	Trading Symbol TradingSymbol	RGLS
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CY2018	rgls	Defined Contribution Minimum Age Requirement Of Eligible Employees DefinedContributionMinimumAgeRequirementOfEligibleEmployees	P18Y
CY2018	rgls	Defined Contribution Plan Employee Contributions Percentageof Eligible Compensation DefinedContributionPlanEmployeeContributionsPercentageofEligibleCompensation	0.5
CY2016	rgls	Effective Income Tax Rate Reconciliation Reservefor Uncertain Tax Positions Amount EffectiveIncomeTaxRateReconciliationReserveforUncertainTaxPositionsAmount	1314000	USD
CY2017	rgls	Effective Income Tax Rate Reconciliation Reservefor Uncertain Tax Positions Amount EffectiveIncomeTaxRateReconciliationReserveforUncertainTaxPositionsAmount	311000	USD
CY2018	rgls	Effective Income Tax Rate Reconciliation Reservefor Uncertain Tax Positions Amount EffectiveIncomeTaxRateReconciliationReserveforUncertainTaxPositionsAmount	3596000	USD
CY2016	rgls	Effective Income Tax Rate Reconciliation Tax Cutsand Jobs Actof2017 Amount EffectiveIncomeTaxRateReconciliationTaxCutsandJobsActof2017Amount	0	USD
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CY2018Q4	rgls	Numberof Optionholders NumberofOptionholders	31	optionholder
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CY2018Q4	us-gaap	Allocated Share Based Compensation Expense AllocatedShareBasedCompensationExpense	400000	USD
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CY2018Q4	us-gaap	Deferred Tax Assets Tax Credit Carryforwards Research DeferredTaxAssetsTaxCreditCarryforwardsResearch	33121000	USD
CY2017Q4	us-gaap	Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost	4238000	USD
CY2018Q4	us-gaap	Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost	5033000	USD
CY2017Q4	us-gaap	Deferred Tax Assets Valuation Allowance DeferredTaxAssetsValuationAllowance	102641000	USD
CY2018Q4	us-gaap	Deferred Tax Assets Valuation Allowance DeferredTaxAssetsValuationAllowance	114960000	USD
CY2018Q4	us-gaap	Deferred Tax Assets Valuation Allowance DeferredTaxAssetsValuationAllowance	115000000	USD
CY2017Q4	us-gaap	Deferred Tax Liabilities DeferredTaxLiabilities	408000	USD
CY2018Q4	us-gaap	Deferred Tax Liabilities DeferredTaxLiabilities	176000	USD
CY2016	us-gaap	Defined Contribution Plan Cost Recognized DefinedContributionPlanCostRecognized	200000	USD
CY2017	us-gaap	Defined Contribution Plan Cost Recognized DefinedContributionPlanCostRecognized	100000	USD
CY2018	us-gaap	Defined Contribution Plan Cost Recognized DefinedContributionPlanCostRecognized	100000	USD
CY2018	us-gaap	Defined Contribution Plan Employer Matching Contribution Percent DefinedContributionPlanEmployerMatchingContributionPercent	0.25
CY2018	us-gaap	Defined Contribution Plan Maximum Annual Contributions Per Employee Percent DefinedContributionPlanMaximumAnnualContributionsPerEmployeePercent	0.06
CY2016	us-gaap	Depreciation Depletion And Amortization DepreciationDepletionAndAmortization	2276000	USD
CY2017	us-gaap	Depreciation Depletion And Amortization DepreciationDepletionAndAmortization	2524000	USD
CY2018	us-gaap	Depreciation Depletion And Amortization DepreciationDepletionAndAmortization	2262000	USD
CY2016	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-18.59
CY2017Q1	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-4.53
CY2017Q2	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-4.87
CY2017Q3	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-2.11
CY2017Q4	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-1.67
CY2017	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-11.47
CY2018Q1	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-1.85
CY2018Q2	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-1.59
CY2018Q3	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-1.18
CY2018Q4	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-0.98
CY2018	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-5.59
CY2018	us-gaap	Effective Income Tax Rate Reconciliation Share Based Compensation Excess Tax Benefit Amount EffectiveIncomeTaxRateReconciliationShareBasedCompensationExcessTaxBenefitAmount	-7700000	USD
CY2017Q2	us-gaap	Employee Benefits And Share Based Compensation Noncash EmployeeBenefitsAndShareBasedCompensationNoncash	1300000	USD
CY2017Q4	us-gaap	Employee Related Liabilities Current EmployeeRelatedLiabilitiesCurrent	1985000	USD
CY2018Q4	us-gaap	Employee Related Liabilities Current EmployeeRelatedLiabilitiesCurrent	1601000	USD
CY2017Q4	us-gaap	Finite Lived Intangible Assets Accumulated Amortization FiniteLivedIntangibleAssetsAccumulatedAmortization	475000	USD
CY2018Q4	us-gaap	Finite Lived Intangible Assets Accumulated Amortization FiniteLivedIntangibleAssetsAccumulatedAmortization	221000	USD
CY2018Q4	us-gaap	Finite Lived Intangible Assets Amortization Expense Next Twelve Months FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths	100000	USD
CY2018Q4	us-gaap	Finite Lived Intangible Assets Amortization Expense Year Five FiniteLivedIntangibleAssetsAmortizationExpenseYearFive	100000	USD
CY2018Q4	us-gaap	Finite Lived Intangible Assets Amortization Expense Year Four FiniteLivedIntangibleAssetsAmortizationExpenseYearFour	100000	USD
CY2018Q4	us-gaap	Finite Lived Intangible Assets Amortization Expense Year Three FiniteLivedIntangibleAssetsAmortizationExpenseYearThree	100000	USD
CY2018Q4	us-gaap	Finite Lived Intangible Assets Amortization Expense Year Two FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo	100000	USD
CY2017Q4	us-gaap	Finite Lived Intangible Assets Gross FiniteLivedIntangibleAssetsGross	1250000	USD
CY2018Q4	us-gaap	Finite Lived Intangible Assets Gross FiniteLivedIntangibleAssetsGross	721000	USD
CY2017Q4	us-gaap	Finite Lived Intangible Assets Net FiniteLivedIntangibleAssetsNet	775000	USD
CY2018Q4	us-gaap	Finite Lived Intangible Assets Net FiniteLivedIntangibleAssetsNet	500000	USD
CY2016	us-gaap	General And Administrative Expense GeneralAndAdministrativeExpense	18391000	USD
CY2017	us-gaap	General And Administrative Expense GeneralAndAdministrativeExpense	17011000	USD
CY2018	us-gaap	General And Administrative Expense GeneralAndAdministrativeExpense	12860000	USD
CY2015Q3	us-gaap	Incentive From Lessor IncentiveFromLessor	1400000	USD
CY2016	us-gaap	Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest	-81840000	USD
CY2017	us-gaap	Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest	-72102000	USD
CY2018	us-gaap	Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest	-48647000	USD
CY2016	us-gaap	Income Tax Expense Benefit IncomeTaxExpenseBenefit	-4000	USD
CY2017	us-gaap	Income Tax Expense Benefit IncomeTaxExpenseBenefit	-197000	USD
CY2018	us-gaap	Income Tax Expense Benefit IncomeTaxExpenseBenefit	62000	USD
CY2016	us-gaap	Income Tax Reconciliation Change In Deferred Tax Assets Valuation Allowance IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance	31990000	USD
CY2017	us-gaap	Income Tax Reconciliation Change In Deferred Tax Assets Valuation Allowance IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance	-8705000	USD
CY2018	us-gaap	Income Tax Reconciliation Change In Deferred Tax Assets Valuation Allowance IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance	12706000	USD
CY2016	us-gaap	Income Tax Reconciliation Income Tax Expense Benefit At Federal Statutory Income Tax Rate IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate	-27826000	USD
CY2017	us-gaap	Income Tax Reconciliation Income Tax Expense Benefit At Federal Statutory Income Tax Rate IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate	-24515000	USD
CY2018	us-gaap	Income Tax Reconciliation Income Tax Expense Benefit At Federal Statutory Income Tax Rate IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate	-10216000	USD
CY2016	us-gaap	Income Tax Reconciliation Nondeductible Expense Share Based Compensation Cost IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost	2458000	USD
CY2017	us-gaap	Income Tax Reconciliation Nondeductible Expense Share Based Compensation Cost IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost	1135000	USD
CY2018	us-gaap	Income Tax Reconciliation Nondeductible Expense Share Based Compensation Cost IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost	251000	USD
CY2016	us-gaap	Income Tax Reconciliation Other Reconciling Items IncomeTaxReconciliationOtherReconcilingItems	-21000	USD
CY2017	us-gaap	Income Tax Reconciliation Other Reconciling Items IncomeTaxReconciliationOtherReconcilingItems	477000	USD
CY2018	us-gaap	Income Tax Reconciliation Other Reconciling Items IncomeTaxReconciliationOtherReconcilingItems	-45000	USD
CY2016	us-gaap	Income Tax Reconciliation Prior Year Income Taxes IncomeTaxReconciliationPriorYearIncomeTaxes	-1320000	USD
CY2017	us-gaap	Income Tax Reconciliation Prior Year Income Taxes IncomeTaxReconciliationPriorYearIncomeTaxes	1000	USD
CY2018	us-gaap	Income Tax Reconciliation Prior Year Income Taxes IncomeTaxReconciliationPriorYearIncomeTaxes	441000	USD
CY2016	us-gaap	Income Tax Reconciliation State And Local Income Taxes IncomeTaxReconciliationStateAndLocalIncomeTaxes	-1152000	USD
CY2017	us-gaap	Income Tax Reconciliation State And Local Income Taxes IncomeTaxReconciliationStateAndLocalIncomeTaxes	1000	USD
CY2018	us-gaap	Income Tax Reconciliation State And Local Income Taxes IncomeTaxReconciliationStateAndLocalIncomeTaxes	-3005000	USD
CY2016	us-gaap	Income Tax Reconciliation Tax Credits IncomeTaxReconciliationTaxCredits	5447000	USD
CY2017	us-gaap	Income Tax Reconciliation Tax Credits IncomeTaxReconciliationTaxCredits	5151000	USD
CY2018	us-gaap	Income Tax Reconciliation Tax Credits IncomeTaxReconciliationTaxCredits	3666000	USD
CY2018	us-gaap	Increase Decrease In Accrued Liabilities IncreaseDecreaseInAccruedLiabilities	-1370000	USD
CY2016	us-gaap	Increase Decrease In Contract With Customer Liability IncreaseDecreaseInContractWithCustomerLiability	-1194000	USD
CY2016	us-gaap	Income Taxes Paid IncomeTaxesPaid	1000	USD
CY2017	us-gaap	Income Taxes Paid IncomeTaxesPaid	1000	USD
CY2018	us-gaap	Income Taxes Paid IncomeTaxesPaid	1000	USD
CY2016	us-gaap	Increase Decrease In Accounts And Other Receivables IncreaseDecreaseInAccountsAndOtherReceivables	-8364000	USD
CY2017	us-gaap	Increase Decrease In Accounts And Other Receivables IncreaseDecreaseInAccountsAndOtherReceivables	-1284000	USD
CY2018	us-gaap	Increase Decrease In Accounts And Other Receivables IncreaseDecreaseInAccountsAndOtherReceivables	-347000	USD
CY2016	us-gaap	Increase Decrease In Accounts Payable IncreaseDecreaseInAccountsPayable	3123000	USD
CY2017	us-gaap	Increase Decrease In Accounts Payable IncreaseDecreaseInAccountsPayable	-65000	USD
CY2018	us-gaap	Increase Decrease In Accounts Payable IncreaseDecreaseInAccountsPayable	-4029000	USD
CY2016	us-gaap	Increase Decrease In Accrued Liabilities IncreaseDecreaseInAccruedLiabilities	-871000	USD
CY2017	us-gaap	Increase Decrease In Accrued Liabilities IncreaseDecreaseInAccruedLiabilities	-492000	USD
CY2017	us-gaap	Increase Decrease In Contract With Customer Liability IncreaseDecreaseInContractWithCustomerLiability	-72000	USD
CY2018	us-gaap	Increase Decrease In Contract With Customer Liability IncreaseDecreaseInContractWithCustomerLiability	2428000	USD
CY2016	us-gaap	Increase Decrease In Deferred Liabilities IncreaseDecreaseInDeferredLiabilities	143000	USD
CY2017	us-gaap	Increase Decrease In Deferred Liabilities IncreaseDecreaseInDeferredLiabilities	-1068000	USD
CY2018	us-gaap	Increase Decrease In Deferred Liabilities IncreaseDecreaseInDeferredLiabilities	-927000	USD
CY2016	us-gaap	Increase Decrease In Employee Related Liabilities IncreaseDecreaseInEmployeeRelatedLiabilities	-74000	USD
CY2017	us-gaap	Increase Decrease In Employee Related Liabilities IncreaseDecreaseInEmployeeRelatedLiabilities	-333000	USD
CY2018	us-gaap	Increase Decrease In Employee Related Liabilities IncreaseDecreaseInEmployeeRelatedLiabilities	-384000	USD
CY2016	us-gaap	Increase Decrease In Other Operating Assets IncreaseDecreaseInOtherOperatingAssets	778000	USD
CY2017	us-gaap	Increase Decrease In Other Operating Assets IncreaseDecreaseInOtherOperatingAssets	-2369000	USD
CY2018	us-gaap	Increase Decrease In Other Operating Assets IncreaseDecreaseInOtherOperatingAssets	-630000	USD
CY2016	us-gaap	Increase Decrease In Prepaid Expense IncreaseDecreaseInPrepaidExpense	616000	USD
CY2017	us-gaap	Increase Decrease In Prepaid Expense IncreaseDecreaseInPrepaidExpense	-394000	USD
CY2018	us-gaap	Increase Decrease In Prepaid Expense IncreaseDecreaseInPrepaidExpense	-134000	USD
CY2017Q4	us-gaap	Intangible Assets Net Excluding Goodwill IntangibleAssetsNetExcludingGoodwill	775000	USD
CY2018Q4	us-gaap	Intangible Assets Net Excluding Goodwill IntangibleAssetsNetExcludingGoodwill	500000	USD
CY2016	us-gaap	Interest And Other Income InterestAndOtherIncome	844000	USD
CY2017	us-gaap	Interest And Other Income InterestAndOtherIncome	752000	USD
CY2018	us-gaap	Interest And Other Income InterestAndOtherIncome	459000	USD
CY2016	us-gaap	Interest Expense InterestExpense	1182000	USD
CY2017	us-gaap	Interest Expense InterestExpense	2723000	USD
CY2018	us-gaap	Interest Expense InterestExpense	2343000	USD
CY2016	us-gaap	Interest Paid Net InterestPaidNet	981000	USD
CY2017	us-gaap	Interest Paid Net InterestPaidNet	1944000	USD
CY2018	us-gaap	Interest Paid Net InterestPaidNet	2073000	USD
CY2016	us-gaap	Lease And Rental Expense LeaseAndRentalExpense	1200000	USD
CY2017	us-gaap	Lease And Rental Expense LeaseAndRentalExpense	1400000	USD
CY2018	us-gaap	Lease And Rental Expense LeaseAndRentalExpense	1300000	USD
CY2018Q4	us-gaap	Lessee Operating Lease Renewal Term LesseeOperatingLeaseRenewalTerm	P5Y
CY2015Q3	us-gaap	Lessee Operating Lease Term Of Contract LesseeOperatingLeaseTermOfContract	P96M
CY2017Q4	us-gaap	Liabilities Liabilities	42593000	USD
CY2018Q4	us-gaap	Liabilities Liabilities	33781000	USD
CY2017Q4	us-gaap	Liabilities And Stockholders Equity LiabilitiesAndStockholdersEquity	77809000	USD
CY2018Q4	us-gaap	Liabilities And Stockholders Equity LiabilitiesAndStockholdersEquity	27927000	USD
CY2017Q4	us-gaap	Liabilities Current LiabilitiesCurrent	32600000	USD
CY2018Q4	us-gaap	Liabilities Current LiabilitiesCurrent	26646000	USD
CY2016	us-gaap	Net Cash Provided By Used In Financing Activities NetCashProvidedByUsedInFinancingActivities	20552000	USD
CY2017Q1	us-gaap	Net Income Loss NetIncomeLoss	-20021000	USD
CY2017Q2	us-gaap	Net Income Loss NetIncomeLoss	-21608000	USD
CY2017	us-gaap	Net Cash Provided By Used In Financing Activities NetCashProvidedByUsedInFinancingActivities	43415000	USD
CY2018	us-gaap	Net Cash Provided By Used In Financing Activities NetCashProvidedByUsedInFinancingActivities	-2830000	USD
CY2016	us-gaap	Net Cash Provided By Used In Investing Activities NetCashProvidedByUsedInInvestingActivities	35311000	USD
CY2017	us-gaap	Net Cash Provided By Used In Investing Activities NetCashProvidedByUsedInInvestingActivities	13936000	USD
CY2018	us-gaap	Net Cash Provided By Used In Investing Activities NetCashProvidedByUsedInInvestingActivities	46519000	USD
CY2016	us-gaap	Net Cash Provided By Used In Operating Activities NetCashProvidedByUsedInOperatingActivities	-56882000	USD
CY2017	us-gaap	Net Cash Provided By Used In Operating Activities NetCashProvidedByUsedInOperatingActivities	-58773000	USD
CY2018	us-gaap	Net Cash Provided By Used In Operating Activities NetCashProvidedByUsedInOperatingActivities	-43273000	USD
CY2016	us-gaap	Net Income Loss NetIncomeLoss	-81836000	USD
CY2017Q3	us-gaap	Net Income Loss NetIncomeLoss	-15828000	USD
CY2017Q4	us-gaap	Net Income Loss NetIncomeLoss	-14448000	USD
CY2017	us-gaap	Net Income Loss NetIncomeLoss	-71905000	USD
CY2018Q1	us-gaap	Net Income Loss NetIncomeLoss	-16025000	USD
CY2018Q2	us-gaap	Net Income Loss NetIncomeLoss	-13847000	USD
CY2018Q3	us-gaap	Net Income Loss NetIncomeLoss	-10273000	USD
CY2018Q4	us-gaap	Net Income Loss NetIncomeLoss	-8563000	USD
CY2018	us-gaap	Net Income Loss NetIncomeLoss	-48709000	USD
CY2018	us-gaap	Number Of Operating Segments NumberOfOperatingSegments	1	segment
CY2016	us-gaap	Operating Expenses OperatingExpenses	82696000	USD
CY2017Q1	us-gaap	Operating Expenses OperatingExpenses	19711000	USD
CY2017Q2	us-gaap	Operating Expenses OperatingExpenses	21335000	USD
CY2017Q3	us-gaap	Operating Expenses OperatingExpenses	15433000	USD
CY2017Q4	us-gaap	Operating Expenses OperatingExpenses	13724000	USD
CY2017	us-gaap	Operating Expenses OperatingExpenses	70203000	USD
CY2018Q1	us-gaap	Operating Expenses OperatingExpenses	15601000	USD
CY2018Q2	us-gaap	Operating Expenses OperatingExpenses	13362000	USD
CY2018Q3	us-gaap	Operating Expenses OperatingExpenses	9872000	USD
CY2018Q4	us-gaap	Operating Expenses OperatingExpenses	8000000	USD
CY2018	us-gaap	Operating Expenses OperatingExpenses	46835000	USD
CY2016	us-gaap	Operating Income Loss OperatingIncomeLoss	-81502000	USD
CY2017	us-gaap	Operating Income Loss OperatingIncomeLoss	-70131000	USD
CY2018	us-gaap	Operating Income Loss OperatingIncomeLoss	-46763000	USD
CY2018Q4	us-gaap	Operating Leases Future Minimum Payments Due OperatingLeasesFutureMinimumPaymentsDue	15094000	USD
CY2018Q4	us-gaap	Operating Leases Future Minimum Payments Due Current OperatingLeasesFutureMinimumPaymentsDueCurrent	2654000	USD
CY2018Q4	us-gaap	Operating Leases Future Minimum Payments Due In Five Years OperatingLeasesFutureMinimumPaymentsDueInFiveYears	2986000	USD
CY2018Q4	us-gaap	Operating Leases Future Minimum Payments Due In Four Years OperatingLeasesFutureMinimumPaymentsDueInFourYears	2901000	USD
CY2018Q4	us-gaap	Operating Leases Future Minimum Payments Due In Three Years OperatingLeasesFutureMinimumPaymentsDueInThreeYears	2815000	USD
CY2018Q4	us-gaap	Operating Leases Future Minimum Payments Due In Two Years OperatingLeasesFutureMinimumPaymentsDueInTwoYears	2733000	USD
CY2018Q4	us-gaap	Operating Leases Future Minimum Payments Due Thereafter OperatingLeasesFutureMinimumPaymentsDueThereafter	1005000	USD
CY2017Q4	us-gaap	Other Assets Noncurrent OtherAssetsNoncurrent	590000	USD
CY2018Q4	us-gaap	Other Assets Noncurrent OtherAssetsNoncurrent	326000	USD
CY2016	us-gaap	Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax	10000	USD
CY2016	us-gaap	Payments To Acquire Property Plant And Equipment PaymentsToAcquirePropertyPlantAndEquipment	913000	USD
CY2017	us-gaap	Payments To Acquire Property Plant And Equipment PaymentsToAcquirePropertyPlantAndEquipment	303000	USD
CY2017	us-gaap	Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax	-11000	USD
CY2018	us-gaap	Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax	0	USD
CY2017Q4	us-gaap	Other Liabilities Noncurrent OtherLiabilitiesNoncurrent	0	USD
CY2018Q4	us-gaap	Other Liabilities Noncurrent OtherLiabilitiesNoncurrent	309000	USD
CY2016	us-gaap	Other Operating Activities Cash Flow Statement OtherOperatingActivitiesCashFlowStatement	1043000	USD
CY2017	us-gaap	Other Operating Activities Cash Flow Statement OtherOperatingActivitiesCashFlowStatement	600000	USD
CY2018	us-gaap	Other Operating Activities Cash Flow Statement OtherOperatingActivitiesCashFlowStatement	756000	USD
CY2017Q4	us-gaap	Other Prepaid Expense Current OtherPrepaidExpenseCurrent	4783000	USD
CY2018Q4	us-gaap	Other Prepaid Expense Current OtherPrepaidExpenseCurrent	4194000	USD
CY2016	us-gaap	Other Significant Noncash Transaction Value Of Consideration Received1 OtherSignificantNoncashTransactionValueOfConsiderationReceived1	6653000	USD
CY2017	us-gaap	Other Significant Noncash Transaction Value Of Consideration Received1 OtherSignificantNoncashTransactionValueOfConsiderationReceived1	0	USD
CY2018	us-gaap	Other Significant Noncash Transaction Value Of Consideration Received1 OtherSignificantNoncashTransactionValueOfConsiderationReceived1	0	USD
CY2016	us-gaap	Payments To Acquire Intangible Assets PaymentsToAcquireIntangibleAssets	53000	USD
CY2017	us-gaap	Payments To Acquire Intangible Assets PaymentsToAcquireIntangibleAssets	16000	USD
CY2018	us-gaap	Payments To Acquire Intangible Assets PaymentsToAcquireIntangibleAssets	0	USD
CY2018	us-gaap	Payments To Acquire Property Plant And Equipment PaymentsToAcquirePropertyPlantAndEquipment	22000	USD
CY2016	us-gaap	Payments To Acquire Short Term Investments PaymentsToAcquireShortTermInvestments	65110000	USD
CY2017	us-gaap	Payments To Acquire Short Term Investments PaymentsToAcquireShortTermInvestments	55686000	USD
CY2018	us-gaap	Payments To Acquire Short Term Investments PaymentsToAcquireShortTermInvestments	0	USD
CY2017Q4	us-gaap	Prepaid Expense And Other Assets Current PrepaidExpenseAndOtherAssetsCurrent	1506000	USD
CY2018Q4	us-gaap	Prepaid Expense And Other Assets Current PrepaidExpenseAndOtherAssetsCurrent	1140000	USD
CY2016	us-gaap	Proceeds From Issuance Of Common Stock ProceedsFromIssuanceOfCommonStock	641000	USD
CY2017	us-gaap	Proceeds From Issuance Of Common Stock ProceedsFromIssuanceOfCommonStock	43411000	USD
CY2018	us-gaap	Proceeds From Issuance Of Common Stock ProceedsFromIssuanceOfCommonStock	219000	USD
CY2016	us-gaap	Proceeds From Issuance Of Other Long Term Debt ProceedsFromIssuanceOfOtherLongTermDebt	19768000	USD
CY2017	us-gaap	Proceeds From Issuance Of Other Long Term Debt ProceedsFromIssuanceOfOtherLongTermDebt	0	USD
CY2018	us-gaap	Proceeds From Issuance Of Other Long Term Debt ProceedsFromIssuanceOfOtherLongTermDebt	0	USD
CY2016	us-gaap	Proceeds From Sale Maturity And Collection Of Shortterm Investments ProceedsFromSaleMaturityAndCollectionOfShorttermInvestments	101387000	USD
CY2017	us-gaap	Proceeds From Sale Maturity And Collection Of Shortterm Investments ProceedsFromSaleMaturityAndCollectionOfShorttermInvestments	69941000	USD
CY2018	us-gaap	Proceeds From Sale Maturity And Collection Of Shortterm Investments ProceedsFromSaleMaturityAndCollectionOfShorttermInvestments	46541000	USD
CY2016	us-gaap	Proceeds From Stock Options Exercised ProceedsFromStockOptionsExercised	310000	USD
CY2017	us-gaap	Proceeds From Stock Options Exercised ProceedsFromStockOptionsExercised	4000	USD
CY2018	us-gaap	Proceeds From Stock Options Exercised ProceedsFromStockOptionsExercised	1000	USD
CY2017Q4	us-gaap	Property Plant And Equipment Gross PropertyPlantAndEquipmentGross	17967000	USD
CY2018Q4	us-gaap	Property Plant And Equipment Gross PropertyPlantAndEquipmentGross	17700000	USD
CY2017Q4	us-gaap	Property Plant And Equipment Net PropertyPlantAndEquipmentNet	9708000	USD
CY2018Q4	us-gaap	Property Plant And Equipment Net PropertyPlantAndEquipmentNet	7806000	USD
CY2016	us-gaap	Repayments Of Other Long Term Debt RepaymentsOfOtherLongTermDebt	167000	USD
CY2017	us-gaap	Repayments Of Other Long Term Debt RepaymentsOfOtherLongTermDebt	0	USD
CY2018	us-gaap	Repayments Of Other Long Term Debt RepaymentsOfOtherLongTermDebt	3342000	USD
CY2016	us-gaap	Research And Development Expense ResearchAndDevelopmentExpense	64305000	USD
CY2017	us-gaap	Research And Development Expense ResearchAndDevelopmentExpense	53192000	USD
CY2018	us-gaap	Research And Development Expense ResearchAndDevelopmentExpense	33975000	USD
CY2017Q4	us-gaap	Restricted Cash And Cash Equivalents At Carrying Value RestrictedCashAndCashEquivalentsAtCarryingValue	0	USD
CY2018Q4	us-gaap	Retained Earnings Accumulated Deficit RetainedEarningsAccumulatedDeficit	-392723000	USD
CY2018Q1	us-gaap	Retained Earnings Accumulated Deficit RetainedEarningsAccumulatedDeficit	-344014000	USD
CY2018Q4	us-gaap	Restricted Cash And Cash Equivalents At Carrying Value RestrictedCashAndCashEquivalentsAtCarryingValue	0	USD
CY2017Q4	us-gaap	Retained Earnings Accumulated Deficit RetainedEarningsAccumulatedDeficit	-345858000	USD
CY2016	us-gaap	Revenue From Contract With Customer Excluding Assessed Tax RevenueFromContractWithCustomerExcludingAssessedTax	1194000	USD
CY2017Q1	us-gaap	Revenue From Contract With Customer Excluding Assessed Tax RevenueFromContractWithCustomerExcludingAssessedTax	18000	USD
CY2017Q2	us-gaap	Revenue From Contract With Customer Excluding Assessed Tax RevenueFromContractWithCustomerExcludingAssessedTax	18000	USD
CY2017Q3	us-gaap	Revenue From Contract With Customer Excluding Assessed Tax RevenueFromContractWithCustomerExcludingAssessedTax	18000	USD
CY2017Q4	us-gaap	Revenue From Contract With Customer Excluding Assessed Tax RevenueFromContractWithCustomerExcludingAssessedTax	18000	USD
CY2017	us-gaap	Revenue From Contract With Customer Excluding Assessed Tax RevenueFromContractWithCustomerExcludingAssessedTax	72000	USD
CY2018Q1	us-gaap	Revenue From Contract With Customer Excluding Assessed Tax RevenueFromContractWithCustomerExcludingAssessedTax	18000	USD
CY2018Q2	us-gaap	Revenue From Contract With Customer Excluding Assessed Tax RevenueFromContractWithCustomerExcludingAssessedTax	18000	USD
CY2018Q3	us-gaap	Revenue From Contract With Customer Excluding Assessed Tax RevenueFromContractWithCustomerExcludingAssessedTax	18000	USD
CY2018Q4	us-gaap	Revenue From Contract With Customer Excluding Assessed Tax RevenueFromContractWithCustomerExcludingAssessedTax	18000	USD
CY2018	us-gaap	Revenue From Contract With Customer Excluding Assessed Tax RevenueFromContractWithCustomerExcludingAssessedTax	72000	USD
CY2017Q2	us-gaap	Severance Costs1 SeveranceCosts1	3200000	USD
CY2018Q3	us-gaap	Severance Costs1 SeveranceCosts1	800000	USD
CY2016	us-gaap	Share Based Compensation ShareBasedCompensation	12872000	USD
CY2017	us-gaap	Share Based Compensation ShareBasedCompensation	7642000	USD
CY2018	us-gaap	Share Based Compensation ShareBasedCompensation	5441000	USD
CY2018Q4	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice	4.56
CY2018Q4	us-gaap	Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber	59000	shares
CY2017Q4	us-gaap	Short Term Investments ShortTermInvestments	46555000	USD
CY2018Q4	us-gaap	Short Term Investments ShortTermInvestments	0	USD
CY2018Q4	us-gaap	Stock Issued During Period Shares Restricted Stock Award Gross StockIssuedDuringPeriodSharesRestrictedStockAwardGross	603058	shares
CY2016	us-gaap	Stock Issued During Period Value Employee Stock Purchase Plan StockIssuedDuringPeriodValueEmployeeStockPurchasePlan	641000	USD
CY2017	us-gaap	Stock Issued During Period Value Employee Stock Purchase Plan StockIssuedDuringPeriodValueEmployeeStockPurchasePlan	419000	USD
CY2018	us-gaap	Stock Issued During Period Value Employee Stock Purchase Plan StockIssuedDuringPeriodValueEmployeeStockPurchasePlan	219000	USD
CY2017	us-gaap	Stock Issued During Period Value New Issues StockIssuedDuringPeriodValueNewIssues	42992000	USD
CY2016	us-gaap	Stock Issued During Period Value Stock Options Exercised StockIssuedDuringPeriodValueStockOptionsExercised	310000	USD
CY2017	us-gaap	Stock Issued During Period Value Stock Options Exercised StockIssuedDuringPeriodValueStockOptionsExercised	4000	USD
CY2018	us-gaap	Stock Issued During Period Value Stock Options Exercised StockIssuedDuringPeriodValueStockOptionsExercised	1000	USD
CY2015Q4	us-gaap	Stockholders Equity StockholdersEquity	124078000	USD
CY2016Q4	us-gaap	Stockholders Equity StockholdersEquity	56075000	USD
CY2017Q4	us-gaap	Stockholders Equity StockholdersEquity	35216000	USD
CY2018Q4	us-gaap	Stockholders Equity StockholdersEquity	-5854000	USD
CY2018	us-gaap	Stockholders Equity Note Stock Split Conversion Ratio1 StockholdersEquityNoteStockSplitConversionRatio1	0.08333
CY2015Q4	us-gaap	Unrecognized Tax Benefits UnrecognizedTaxBenefits	2298000	USD
CY2016Q4	us-gaap	Unrecognized Tax Benefits UnrecognizedTaxBenefits	5632000	USD
CY2017Q4	us-gaap	Unrecognized Tax Benefits UnrecognizedTaxBenefits	4421000	USD
CY2018Q4	us-gaap	Unrecognized Tax Benefits UnrecognizedTaxBenefits	14700000	USD
CY2018Q4	us-gaap	Unrecognized Tax Benefits UnrecognizedTaxBenefits	14700000	USD
CY2016Q4	us-gaap	Unrecognized Tax Benefits Income Tax Penalties And Interest Accrued UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued	0	USD
CY2017Q4	us-gaap	Unrecognized Tax Benefits Income Tax Penalties And Interest Accrued UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued	0	USD
CY2018Q4	us-gaap	Unrecognized Tax Benefits Income Tax Penalties And Interest Accrued UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued	0	USD
CY2016	us-gaap	Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions	1343000	USD
CY2017	us-gaap	Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions	1255000	USD
CY2018	us-gaap	Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions	4318000	USD
CY2018Q4	us-gaap	Unrecognized Tax Benefits That Would Impact Effective Tax Rate UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate	11800000	USD
CY2017	us-gaap	Valuation Allowance Deferred Tax Asset Change In Amount ValuationAllowanceDeferredTaxAssetChangeInAmount	-36200000	USD
CY2016	us-gaap	Weighted Average Number Of Share Outstanding Basic And Diluted WeightedAverageNumberOfShareOutstandingBasicAndDiluted	4401701	shares
CY2017	us-gaap	Weighted Average Number Of Share Outstanding Basic And Diluted WeightedAverageNumberOfShareOutstandingBasicAndDiluted	6269758	shares
CY2018	us-gaap	Weighted Average Number Of Share Outstanding Basic And Diluted WeightedAverageNumberOfShareOutstandingBasicAndDiluted	8718563	shares
CY2018	us-gaap	Concentration Risk Credit Risk ConcentrationRiskCreditRisk	<div style="font-family:Times New Roman;font-size:10pt;"><div style="line-height:120%;padding-top:20px;text-align:left;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;font-weight:bold;">Concentrations of Credit Risk </font></div><div style="line-height:120%;padding-top:4px;text-align:left;text-indent:32px;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">Financial instruments that potentially subject us to significant concentrations of credit risk consist primarily of cash equivalents and short-term investments. We maintain deposits in federally insured financial institutions in excess of federally insured limits. We have not experienced any material losses in such accounts and believe we are not exposed to significant risk. We maintain our cash equivalents and short-term investments with two highly accredited financial institutions. We have historically invested our excess cash primarily in certificates of deposit and debt instruments of financial institutions and corporations, United States Treasury securities and United States government-sponsored enterprise securities. Additionally, we adhere to established guidelines regarding approved investments and maturities of investments, which are designed to preserve their principal value and maintain liquidity.</font></div></div>
CY2018	us-gaap	Use Of Estimates UseOfEstimates	<div style="font-family:Times New Roman;font-size:10pt;"><div style="line-height:120%;padding-top:24px;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;font-weight:bold;">Use of Estimates</font></div><div style="line-height:120%;padding-top:8px;text-indent:32px;font-size:10pt;"><font style="font-family:inherit;font-size:10pt;">Our financial statements are prepared in accordance with U.S. generally accepted accounting principles ("GAAP"), which requires us to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenues and expenses and the disclosure of contingent assets and liabilities in our financial statements and accompanying notes. An estimated loss contingency is accrued in our financial statements if it is probable that a liability has been incurred and the amount of the loss can be reasonably estimated. Although these estimates are based on our knowledge of current events and actions we may undertake in the future, actual results may ultimately differ from these estimates and assumptions.</font></div></div>

Files In Submission

Name	View Source	Status
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rgls-20181231_pre.xml	Edgar Link	unprocessable
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$RGLS
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2019 Q1 Form 10-K Financial Statement

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$RGLS Regulus Therapeutics Inc. Stock $rgls

2019 Q1 Form 10-K Financial Statement

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$RGLS
Regulus Therapeutics Inc. Stock $rgls