2020 Form 10-K Financial Statement
#000155837021002121 Filed on March 01, 2021
Income Statement
Concept | 2020 | 2019 Q4 | 2019 |
---|---|---|---|
Revenue | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Cost Of Revenue | |||
YoY Change | |||
Gross Profit | |||
YoY Change | |||
Gross Profit Margin | |||
Selling, General & Admin | $46.13M | $9.420M | $36.55M |
YoY Change | 26.2% | 12.28% | 30.16% |
% of Gross Profit | |||
Research & Development | $90.45M | $24.81M | $109.5M |
YoY Change | -17.36% | 32.25% | 117.43% |
% of Gross Profit | |||
Depreciation & Amortization | $690.0K | $190.0K | $834.0K |
YoY Change | -17.27% | -9.52% | 88.69% |
% of Gross Profit | |||
Operating Expenses | $136.6M | $34.22M | $146.0M |
YoY Change | -6.46% | 26.04% | 86.18% |
Operating Profit | -$136.6M | -$146.0M | |
YoY Change | -6.46% | 86.18% | |
Interest Expense | $2.580M | $1.270M | $5.270M |
YoY Change | -51.04% | -22.56% | 21.15% |
% of Operating Profit | |||
Other Income/Expense, Net | $2.579M | $0.00 | $5.271M |
YoY Change | -51.07% | 21.09% | |
Pretax Income | -$134.0M | -$32.96M | -$140.7M |
YoY Change | -4.78% | 29.2% | 90.02% |
Income Tax | |||
% Of Pretax Income | |||
Net Earnings | -$134.0M | -$32.96M | -$140.7M |
YoY Change | -4.78% | 29.2% | 90.01% |
Net Earnings / Revenue | |||
Basic Earnings Per Share | -$3.04 | -$3.86 | |
Diluted Earnings Per Share | -$3.04 | -$779.6K | -$3.86 |
COMMON SHARES | |||
Basic Shares Outstanding | 44.13M | 36.42M | |
Diluted Shares Outstanding | 44.13M | 36.42M |
Balance Sheet
Concept | 2020 | 2019 Q4 | 2019 |
---|---|---|---|
SHORT-TERM ASSETS | |||
Cash & Short-Term Investments | $172.8M | $292.5M | $292.5M |
YoY Change | -40.92% | 16.03% | 16.03% |
Cash & Equivalents | $100.9M | $62.29M | $62.30M |
Short-Term Investments | $71.90M | $230.2M | $230.2M |
Other Short-Term Assets | $8.800M | $3.507M | $9.900M |
YoY Change | -11.11% | -46.86% | 50.0% |
Inventory | |||
Prepaid Expenses | |||
Receivables | |||
Other Receivables | |||
Total Short-Term Assets | $181.7M | $302.4M | $302.4M |
YoY Change | -39.91% | 16.89% | 16.89% |
LONG-TERM ASSETS | |||
Property, Plant & Equipment | $5.000M | $3.671M | $5.700M |
YoY Change | -12.28% | 233.73% | 418.18% |
Goodwill | |||
YoY Change | |||
Intangibles | |||
YoY Change | |||
Long-Term Investments | |||
YoY Change | |||
Other Assets | $400.0K | $400.0K | $400.0K |
YoY Change | 0.0% | 0.0% | 0.0% |
Total Long-Term Assets | $5.400M | $6.119M | $6.100M |
YoY Change | -11.48% | 307.93% | 306.67% |
TOTAL ASSETS | |||
Total Short-Term Assets | $181.7M | $302.4M | $302.4M |
Total Long-Term Assets | $5.400M | $6.119M | $6.100M |
Total Assets | $187.1M | $308.5M | $308.5M |
YoY Change | -39.35% | 18.57% | 18.56% |
SHORT-TERM LIABILITIES | |||
YoY Change | |||
Accounts Payable | $4.900M | $10.42M | $10.40M |
YoY Change | -52.88% | 37.04% | 36.84% |
Accrued Expenses | $13.10M | $13.53M | $14.00M |
YoY Change | -6.43% | 129.32% | 137.29% |
Deferred Revenue | |||
YoY Change | |||
Short-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Long-Term Debt Due | |||
YoY Change | |||
Total Short-Term Liabilities | $18.00M | $24.42M | $24.40M |
YoY Change | -26.23% | 79.54% | 79.41% |
LONG-TERM LIABILITIES | |||
Long-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Other Long-Term Liabilities | $2.600M | $3.100M | $3.100M |
YoY Change | -16.13% | 675.0% | 675.0% |
Total Long-Term Liabilities | $2.600M | $3.100M | $3.100M |
YoY Change | -16.13% | 675.0% | 675.0% |
TOTAL LIABILITIES | |||
Total Short-Term Liabilities | $18.00M | $24.42M | $24.40M |
Total Long-Term Liabilities | $2.600M | $3.100M | $3.100M |
Total Liabilities | $20.50M | $27.50M | $27.50M |
YoY Change | -25.45% | 96.45% | 96.43% |
SHAREHOLDERS EQUITY | |||
Retained Earnings | -$325.3M | ||
YoY Change | |||
Common Stock | $44.00K | ||
YoY Change | |||
Preferred Stock | |||
YoY Change | |||
Treasury Stock (at cost) | |||
YoY Change | |||
Treasury Stock Shares | |||
Shareholders Equity | $166.5M | $281.0M | $281.0M |
YoY Change | |||
Total Liabilities & Shareholders Equity | $187.1M | $308.5M | $308.5M |
YoY Change | -39.35% | 18.57% | 18.56% |
Cashflow Statement
Concept | 2020 | 2019 Q4 | 2019 |
---|---|---|---|
OPERATING ACTIVITIES | |||
Net Income | -$134.0M | -$32.96M | -$140.7M |
YoY Change | -4.78% | 29.2% | 90.01% |
Depreciation, Depletion And Amortization | $690.0K | $190.0K | $834.0K |
YoY Change | -17.27% | -9.52% | 88.69% |
Cash From Operating Activities | -$122.0M | -$32.22M | -$122.8M |
YoY Change | -0.63% | 53.5% | 97.81% |
INVESTING ACTIVITIES | |||
Capital Expenditures | $214.0K | $0.00 | $3.385M |
YoY Change | -93.68% | -100.0% | 368.84% |
Acquisitions | |||
YoY Change | |||
Other Investing Activities | $158.8M | -$139.1M | -$24.59M |
YoY Change | -745.59% | -1198.11% | -71.55% |
Cash From Investing Activities | $158.5M | -$139.1M | -$27.97M |
YoY Change | -666.79% | -1233.9% | -67.91% |
FINANCING ACTIVITIES | |||
Cash Dividend Paid | |||
YoY Change | |||
Common Stock Issuance & Retirement, Net | $161.4M | $161.4M | |
YoY Change | -0.94% | ||
Debt Paid & Issued, Net | |||
YoY Change | |||
Cash From Financing Activities | 2.009M | 162.0M | 163.5M |
YoY Change | -98.77% | 101125.0% | -0.74% |
NET CHANGE | |||
Cash From Operating Activities | -122.0M | -32.22M | -122.8M |
Cash From Investing Activities | 158.5M | -139.1M | -27.97M |
Cash From Financing Activities | 2.009M | 162.0M | 163.5M |
Net Change In Cash | 38.56M | -9.390M | 12.75M |
YoY Change | 202.34% | 9.7% | -17.62% |
FREE CASH FLOW | |||
Cash From Operating Activities | -$122.0M | -$32.22M | -$122.8M |
Capital Expenditures | $214.0K | $0.00 | $3.385M |
Free Cash Flow | -$122.2M | -$32.22M | -$126.1M |
YoY Change | -3.12% | 56.41% | 100.92% |
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MarketableSecuritiesUnrealizedGainLoss
|
49000 | |
CY2020 | us-gaap |
Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
|
-133996000 | |
CY2020Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
166528000 | |
CY2020 | us-gaap |
Profit Loss
ProfitLoss
|
-133996000 | |
CY2019 | us-gaap |
Profit Loss
ProfitLoss
|
-140729000 | |
CY2018 | us-gaap |
Profit Loss
ProfitLoss
|
-74064000 | |
CY2018 | rytm |
Non Cash Research And Development License Expense
NonCashResearchAndDevelopmentLicenseExpense
|
4448000 | |
CY2020 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
17455000 | |
CY2018 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
442000 | |
CY2020 | rytm |
Deferred Rent Expense
DeferredRentExpense
|
-234000 | |
CY2019 | rytm |
Deferred Rent Expense
DeferredRentExpense
|
203000 | |
CY2018 | rytm |
Deferred Rent Expense
DeferredRentExpense
|
61000 | |
CY2020 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
-551000 | |
CY2019 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
6378000 | |
CY2018 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
6286000 | |
CY2019 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
11875000 | |
CY2018 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
6390000 | |
CY2020 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
690000 | |
CY2019 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
834000 | |
CY2019 | rytm |
Increase Decrease In Tenant Improvement Allowance
IncreaseDecreaseInTenantImprovementAllowance
|
-938000 | |
CY2020 | us-gaap |
Increase Decrease In Accounts Payable And Accrued Liabilities
IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
|
-6446000 | |
CY2019 | us-gaap |
Increase Decrease In Accounts Payable And Accrued Liabilities
IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
|
10507000 | |
CY2018 | us-gaap |
Increase Decrease In Accounts Payable And Accrued Liabilities
IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
|
6953000 | |
CY2020 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-121980000 | |
CY2019 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-122750000 | |
CY2018 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-62056000 | |
CY2020 | us-gaap |
Payments To Acquire Short Term Investments
PaymentsToAcquireShortTermInvestments
|
86869000 | |
CY2019 | us-gaap |
Payments To Acquire Short Term Investments
PaymentsToAcquireShortTermInvestments
|
295825000 | |
CY2018 | us-gaap |
Payments To Acquire Short Term Investments
PaymentsToAcquireShortTermInvestments
|
248592000 | |
CY2020 | us-gaap |
Proceeds From Maturities Prepayments And Calls Of Shortterm Investments
ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments
|
245614000 | |
CY2019 | us-gaap |
Proceeds From Maturities Prepayments And Calls Of Shortterm Investments
ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments
|
271240000 | |
CY2018 | us-gaap |
Proceeds From Maturities Prepayments And Calls Of Shortterm Investments
ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments
|
162166000 | |
CY2020 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
214000 | |
CY2019 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
3385000 | |
CY2018 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
722000 | |
CY2020 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
158531000 | |
CY2019 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
-27970000 | |
CY2018 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
-87148000 | |
CY2019 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
161352000 | |
CY2018 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
162878000 | |
CY2020 | us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
1487000 | |
CY2019 | us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
1564000 | |
CY2018 | us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
1808000 | |
CY2020 | us-gaap |
Proceeds From Stock Plans
ProceedsFromStockPlans
|
522000 | |
CY2019 | us-gaap |
Proceeds From Stock Plans
ProceedsFromStockPlans
|
558000 | |
CY2020 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
2009000 | |
CY2019 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
163474000 | |
CY2018 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
164686000 | |
CY2020 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
38560000 | |
CY2019 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
12754000 | |
CY2018 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
15482000 | |
CY2019Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
62697000 | |
CY2018Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
49943000 | |
CY2017Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
34461000 | |
CY2020Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
101257000 | |
CY2019Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
62697000 | |
CY2018Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
49943000 | |
CY2020 | us-gaap |
Nature Of Operations
NatureOfOperations
|
<p style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-weight:bold;margin:0pt 0pt 12pt 0pt;">1. Nature of Business</p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;text-indent:43.2pt;margin:0pt 0pt 12pt 0pt;">Rhythm Pharmaceuticals, Inc. (the “Company” or “We”), is a commercial-stage biopharmaceutical company focused on changing the paradigm for the treatment of rare genetic diseases of obesity, which are characterized by early-onset, severe obesity and an insatiable hunger or hyperphagia. Our lead product candidate is IMCIVREE (setmelanotide), a potent melanocortin-4 receptor, or MC4R, agonist for the treatment of rare genetic diseases of obesity. We believe IMCIVREE, for which we have exclusive worldwide rights, has the potential to restore dysfunctional MC4R signaling due to impaired MC4R pathway function. MC4R pathway deficiencies result in the disruption of satiety signals and energy homeostasis in the body, which, in turn, leads to intense feelings of hunger and to obesity. IMCIVREE has been approved by the U.S. Food and Drug Administration, or FDA, for chronic weight management in adult and pediatric patients six years of age and older with obesity due to proopiomelanocortin, or POMC, proprotein convertase subtilisin/kexin type 1, or PCSK1, or leptin receptor, or LEPR, deficiency confirmed by genetic testing. We expect IMCIVREE to be commercially available in the first quarter of 2021.</p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;text-indent:43.2pt;margin:0pt 0pt 12pt 0pt;">The Company is a Delaware corporation organized in February 2013 under the name Rhythm Metabolic, Inc., and as of October 2015, under the name Rhythm Pharmaceuticals, Inc.</p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;text-indent:36pt;margin:0pt 0pt 12pt 0pt;">The Company’s continued development efforts are focused on obesity related to several single gene-related, or monogenic, MC4R pathway deficiencies: Bardet-Biedl syndrome, or BBS; Alström syndrome; POMC or LEPR heterozygous deficiency obesity; steroid receptor coactivator 1, or SRC1, deficiency obesity; SH2B adapter protein 1, or SH2B1, deficiency obesity; MC4R deficiency obesity and Smith-Magenis syndrome, as well as additional disorders as part of investigator-initiated protocols. Currently, there are no effective or approved treatments for these MC4R pathway-related disorders. The Company believes that the MC4R pathway is a compelling target for treating these genetic disorders because of its critical role in regulating appetite and weight by promoting satiety and weight control, and that peptide therapeutics are uniquely suited for activating this target. </p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;text-indent:36pt;margin:0pt 0pt 12pt 0pt;"><span style="white-space:pre-wrap;"> </span>In March 2018, the Company acquired exclusive, worldwide rights from Takeda Pharmaceutical Company Limited (“Takeda”) to develop and commercialize T-3525770 (now “RM-853”). RM-853 is a potent, orally available ghrelin o-acyltransferase (“GOAT”) inhibitor currently in preclinical development for Prader-Willi Syndrome (“PWS”). PWS is a rare genetic disorder that results in hyperphagia and early-onset, life-threatening obesity, for which there are no approved therapeutic options.</p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;text-indent:36pt;margin:0pt 0pt 12pt 0pt;"><span style="background-color:#ffffff;">The Company is subject to risks and uncertainties common to late-stage companies in the biotechnology industry, including but not limited to, risks associated with the commercialization of approved products, completing preclinical studies and clinical trials, receiving regulatory approvals for product candidates, development by competitors of new biopharmaceutical products, dependence on key personnel, protection of proprietary technology, compliance with government regulations and the ability to secure additional capital to fund operations. Commercialization of approved products will require significant resources and in order to market IMCIVREE, the Company must continue to build its sales, marketing, managerial and other non-technical capabilities or make arrangements with third parties to perform these services. Product candidates currently under development will require significant additional research and development efforts, including preclinical and clinical testing and regulatory approval, prior to commercialization. These efforts require significant amounts of additional capital, adequate personnel and infrastructure and extensive compliance-reporting capabilities. Even though the Company has an approved product, and even if the Company’s further product development efforts are successful, it is uncertain when, if ever, the Company will realize revenue from product sales.</span> </p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-style:italic;font-weight:bold;margin:0pt 0pt 12pt 0pt;">Liquidity</p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;text-indent:36pt;margin:0pt 0pt 12pt 0pt;">The Company has incurred operating losses and negative cash flows from operations since inception. As of December 31, 2020, the Company had an accumulated deficit of $459,327. The Company has primarily funded these losses through the proceeds from the sales of common and preferred stock as well as capital contributions received from the former parent company, Rhythm Holdings LLC. To date, the Company has no product revenue and management expects operating losses to continue for the foreseeable future. The Company has devoted substantially all of its resources to its drug development efforts, comprising of research and development, manufacturing, conducting clinical trials for its product candidates, protecting its intellectual property, pre-commercialization activities and general and administrative functions relating to these operations. The future success of the Company is dependent on its ability to develop its product candidates and ultimately upon its ability to attain profitable operations. </p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;text-indent:36pt;margin:0pt;">At December 31, 2020, the Company had $172,792 of cash and cash equivalents and short-term investments on hand. Subsequent to year end, the Company received additional funding in connection with the sale of a Rare Pediatric Disease Priority Review Voucher, or PRV, and a public offering (see Note 12, “Subsequent Events”). The net proceeds from the sale of the PRV Transfer and this offering, or the February 2021 public offering, were approximately $260,050 after deducting underwriting discounts and commissions and estimated offering expenses. In the future, the Company will be dependent on obtaining funding from third parties, such as proceeds from the issuance of debt, sale of equity and funded research and development programs, to maintain the Company's operations and meet the Company's obligations. There is no guarantee that additional equity or other financings will be available to the Company on acceptable terms, or at all. If the Company fails to obtain additional funding when needed, the Company would be forced to scale back, terminate its operations or seek to merge with or be acquired by another company. Management believes that the Company's existing cash resources will be sufficient to fund the Company's operations through at least the next twelve months from the filing of this Annual Report on Form 10-K with the SEC. </p> | |
CY2020Q4 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-459327000 | |
CY2018 | us-gaap |
Revenue From Contract With Customer Including Assessed Tax
RevenueFromContractWithCustomerIncludingAssessedTax
|
0 | |
CY2019 | us-gaap |
Revenue From Contract With Customer Including Assessed Tax
RevenueFromContractWithCustomerIncludingAssessedTax
|
0 | |
CY2020 | us-gaap |
Revenue From Contract With Customer Including Assessed Tax
RevenueFromContractWithCustomerIncludingAssessedTax
|
0 | |
CY2020Q4 | us-gaap |
Cash Cash Equivalents And Short Term Investments
CashCashEquivalentsAndShortTermInvestments
|
172792000 | |
CY2021Q1 | us-gaap |
Proceeds From Divestiture Of Businesses Net Of Cash Divested
ProceedsFromDivestitureOfBusinessesNetOfCashDivested
|
260050000 | |
CY2020 | us-gaap |
Use Of Estimates
UseOfEstimates
|
<p style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-style:italic;font-weight:bold;margin:0pt 0pt 12pt 0pt;">Use of Estimates</p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;text-indent:36pt;margin:0pt 0pt 12pt 0pt;">The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent liabilities at the date of the financial statements and the reported amounts of revenue and expenses during the reporting period. The Company bases its estimates on historical experience and other market-specific or other relevant assumptions that it believes to be reasonable under the circumstances. This process may result in actual results differing materially from those estimated amounts used in the preparation of the financial statements if these results differ from historical experience, or other assumptions do not turn out to be substantially accurate, even if such assumptions are reasonable when made. Significant estimates relied upon in preparing these financial statements include accruals related to research and development expenses, assumptions used to record stock-based compensation expense and the valuation allowance on the Company's deferred tax assets. Estimates are periodically reviewed in light of changes in circumstances, facts and experience. Changes in estimates are recorded in the period in which they become known. Actual results could differ materially from those estimates.</p> | |
CY2020 | rytm |
Number Of Federally Insured Financial Institutions
NumberOfFederallyInsuredFinancialInstitutions
|
2 | |
CY2020 | rytm |
Number Of Federally Insured Financial Institutions
NumberOfFederallyInsuredFinancialInstitutions
|
2 | |
CY2020 | us-gaap |
Number Of Operating Segments
NumberOfOperatingSegments
|
1 | |
CY2020Q4 | rytm |
Prepaid Research And Development Expense
PrepaidResearchAndDevelopmentExpense
|
5828000 | |
CY2019Q4 | rytm |
Prepaid Research And Development Expense
PrepaidResearchAndDevelopmentExpense
|
6438000 | |
CY2020Q4 | us-gaap |
Other Assets Current
OtherAssetsCurrent
|
3048000 | |
CY2019Q4 | us-gaap |
Other Assets Current
OtherAssetsCurrent
|
3507000 | |
CY2020Q4 | us-gaap |
Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
|
8876000 | |
CY2019Q4 | us-gaap |
Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
|
9945000 | |
CY2020Q4 | us-gaap |
Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
|
4637000 | |
CY2019Q4 | us-gaap |
Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
|
4423000 | |
CY2020Q4 | us-gaap |
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
|
1442000 | |
CY2019Q4 | us-gaap |
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
|
752000 | |
CY2020Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
3195000 | |
CY2019Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
3671000 | |
CY2020 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
690000 | |
CY2019 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
834000 | |
CY2018 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
442000 | |
CY2020 | rytm |
Number Of Patients
NumberOfPatients
|
36 | |
CY2020 | rytm |
Maximum Amount Of Grants To Be Received
MaximumAmountOfGrantsToBeReceived
|
999000 | |
CY2020 | us-gaap |
Unrecognized Tax Benefits Income Tax Penalties And Interest Expense
UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense
|
0 | |
CY2020 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
5375772 | |
CY2019 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
3428497 | |
CY2018 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
2616530 | |
CY2018Q4 | us-gaap |
Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
|
3265000 | |
CY2018Q4 | us-gaap |
Operating Lease Liability
OperatingLeaseLiability
|
3636000 | |
CY2020Q4 | rytm |
Accrued Research And Development Costs
AccruedResearchAndDevelopmentCosts
|
5815000 | |
CY2019Q4 | rytm |
Accrued Research And Development Costs
AccruedResearchAndDevelopmentCosts
|
8059000 | |
CY2020Q4 | us-gaap |
Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
|
648000 | |
CY2019Q4 | us-gaap |
Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
|
1439000 | |
CY2020Q4 | rytm |
Accrued Payroll Related Expense Current
AccruedPayrollRelatedExpenseCurrent
|
5916000 | |
CY2019Q4 | rytm |
Accrued Payroll Related Expense Current
AccruedPayrollRelatedExpenseCurrent
|
3655000 | |
CY2020Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
180000 | |
CY2019Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
377000 | |
CY2020Q4 | us-gaap |
Accrued Liabilities Current
AccruedLiabilitiesCurrent
|
12559000 | |
CY2019Q4 | us-gaap |
Accrued Liabilities Current
AccruedLiabilitiesCurrent
|
13530000 | |
CY2020Q4 | us-gaap |
Cash Cash Equivalents And Short Term Investments
CashCashEquivalentsAndShortTermInvestments
|
172792000 | |
CY2019Q4 | us-gaap |
Cash Cash Equivalents And Short Term Investments
CashCashEquivalentsAndShortTermInvestments
|
292459000 | |
CY2020Q4 | us-gaap |
Available For Sale Debt Securities Amortized Cost Basis
AvailableForSaleDebtSecuritiesAmortizedCostBasis
|
71895000 | |
CY2020Q4 | us-gaap |
Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
|
43000 | |
CY2020Q4 | us-gaap |
Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
|
71938000 | |
CY2019Q4 | us-gaap |
Available For Sale Debt Securities Amortized Cost Basis
AvailableForSaleDebtSecuritiesAmortizedCostBasis
|
230155000 | |
CY2019Q4 | us-gaap |
Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
|
54000 | |
CY2019Q4 | us-gaap |
Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
|
44000 | |
CY2019Q4 | us-gaap |
Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
|
230165000 | |
CY2020Q4 | us-gaap |
Lessee Operating Lease Remaining Lease Term
LesseeOperatingLeaseRemainingLeaseTerm
|
P4Y7M6D | |
CY2020Q4 | us-gaap |
Lessee Operating Lease Discount Rate
LesseeOperatingLeaseDiscountRate
|
0.10 | |
CY2018 | us-gaap |
Lease Practical Expedients Package
LeasePracticalExpedientsPackage
|
true | |
CY2018Q4 | us-gaap |
Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
|
3265000 | |
CY2018Q4 | us-gaap |
Operating Lease Liability
OperatingLeaseLiability
|
3636000 | |
CY2019Q2 | us-gaap |
Lessee Operating Lease Term Of Contract
LesseeOperatingLeaseTermOfContract
|
P6Y | |
CY2019Q2 | us-gaap |
Lessee Operating Lease Renewal Term
LesseeOperatingLeaseRenewalTerm
|
P5Y | |
CY2018Q4 | us-gaap |
Lessee Operating Lease Renewal Term
LesseeOperatingLeaseRenewalTerm
|
P5Y | |
CY2020 | us-gaap |
Operating Lease Expense
OperatingLeaseExpense
|
551000 | |
CY2019 | us-gaap |
Operating Lease Expense
OperatingLeaseExpense
|
629000 | |
CY2018 | us-gaap |
Operating Lease Expense
OperatingLeaseExpense
|
359000 | |
CY2020 | us-gaap |
Operating Lease Payments Use
OperatingLeasePaymentsUse
|
786000 | |
CY2020Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Next Twelve Months
LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
|
802000 | |
CY2020Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Two
LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
|
818000 | |
CY2020Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Three
LesseeOperatingLeaseLiabilityPaymentsDueYearThree
|
834000 | |
CY2020Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Four
LesseeOperatingLeaseLiabilityPaymentsDueYearFour
|
851000 | |
CY2020Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Five
LesseeOperatingLeaseLiabilityPaymentsDueYearFive
|
502000 | |
CY2020Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
|
3807000 | |
CY2020Q4 | us-gaap |
Lessee Operating Lease Liability Undiscounted Excess Amount
LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
|
721000 | |
CY2020Q4 | us-gaap |
Operating Lease Liability
OperatingLeaseLiability
|
3086000 | |
CY2018Q2 | us-gaap |
Stock Issued During Period Shares New Issues
StockIssuedDuringPeriodSharesNewIssues
|
6591800 | |
CY2018Q2 | us-gaap |
Share Price
SharePrice
|
26.42 | |
CY2018Q2 | rytm |
Proceeds From Issuance Initial Public Offering Net Issuance Cost
ProceedsFromIssuanceInitialPublicOfferingNetIssuanceCost
|
162878000 | |
CY2019Q4 | us-gaap |
Stock Issued During Period Shares New Issues
StockIssuedDuringPeriodSharesNewIssues
|
9324324 | |
CY2019Q4 | us-gaap |
Share Price
SharePrice
|
18.50 | |
CY2019Q4 | rytm |
Proceeds From Issuance Initial Public Offering Net Issuance Cost
ProceedsFromIssuanceInitialPublicOfferingNetIssuanceCost
|
161352000 | |
CY2018 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
7980000 | |
CY2020 | rytm |
Potential Milestone Payment
PotentialMilestonePayment
|
9000000 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.2100 | |
CY2019 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.2100 | |
CY2018 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.2100 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.0632 | |
CY2019 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.0675 | |
CY2018 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.0690 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits Research
EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
|
0.0146 | |
CY2019 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits Research
EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
|
0.0249 | |
CY2018 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits Research
EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
|
0.0152 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation Deductions Medicare Prescription Drug Benefit
EffectiveIncomeTaxRateReconciliationDeductionsMedicarePrescriptionDrugBenefit
|
0.0240 | |
CY2019 | us-gaap |
Effective Income Tax Rate Reconciliation Deductions Medicare Prescription Drug Benefit
EffectiveIncomeTaxRateReconciliationDeductionsMedicarePrescriptionDrugBenefit
|
0.0185 | |
CY2018 | us-gaap |
Effective Income Tax Rate Reconciliation Deductions Medicare Prescription Drug Benefit
EffectiveIncomeTaxRateReconciliationDeductionsMedicarePrescriptionDrugBenefit
|
0.0195 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
|
0.0053 | |
CY2019 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
|
0.0010 | |
CY2018 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
|
-0.0046 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation Other Adjustments
EffectiveIncomeTaxRateReconciliationOtherAdjustments
|
0.0030 | |
CY2019 | us-gaap |
Effective Income Tax Rate Reconciliation Other Adjustments
EffectiveIncomeTaxRateReconciliationOtherAdjustments
|
-0.0020 | |
CY2018 | us-gaap |
Effective Income Tax Rate Reconciliation Other Adjustments
EffectiveIncomeTaxRateReconciliationOtherAdjustments
|
-0.0005 | |
CY2020 | rytm |
Effective Income Tax Rate Reconciliation Change In Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInValuationAllowance
|
0.3035 | |
CY2019 | rytm |
Effective Income Tax Rate Reconciliation Change In Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInValuationAllowance
|
0.3219 | |
CY2018 | rytm |
Effective Income Tax Rate Reconciliation Change In Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInValuationAllowance
|
0.3188 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
102367000 | |
CY2019Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
71524000 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets In Process Research And Development
DeferredTaxAssetsInProcessResearchAndDevelopment
|
10347000 | |
CY2019Q4 | us-gaap |
Deferred Tax Assets In Process Research And Development
DeferredTaxAssetsInProcessResearchAndDevelopment
|
7876000 | |
CY2020Q4 | rytm |
Deferred Tax Assets Orphan Drug Credit
DeferredTaxAssetsOrphanDrugCredit
|
10110000 | |
CY2019Q4 | rytm |
Deferred Tax Assets Orphan Drug Credit
DeferredTaxAssetsOrphanDrugCredit
|
6889000 | |
CY2020Q4 | rytm |
Deferred Tax Assets Capitalized License Fee
DeferredTaxAssetsCapitalizedLicenseFee
|
2492000 | |
CY2019Q4 | rytm |
Deferred Tax Assets Capitalized License Fee
DeferredTaxAssetsCapitalizedLicenseFee
|
1734000 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits
|
6621000 | |
CY2019Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits
|
3628000 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Other
DeferredTaxAssetsOther
|
2267000 | |
CY2019Q4 | us-gaap |
Deferred Tax Assets Other
DeferredTaxAssetsOther
|
2006000 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Gross
DeferredTaxAssetsGross
|
134204000 | |
CY2019Q4 | us-gaap |
Deferred Tax Assets Gross
DeferredTaxAssetsGross
|
93657000 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
133596000 | |
CY2019Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
92943000 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Net
DeferredTaxAssetsNet
|
608000 | |
CY2019Q4 | us-gaap |
Deferred Tax Assets Net
DeferredTaxAssetsNet
|
714000 | |
CY2020Q4 | rytm |
Deferred Tax Liabilities Right Of Use Assets And Other
DeferredTaxLiabilitiesRightOfUseAssetsAndOther
|
608000 | |
CY2019Q4 | rytm |
Deferred Tax Liabilities Right Of Use Assets And Other
DeferredTaxLiabilitiesRightOfUseAssetsAndOther
|
714000 | |
CY2020Q4 | us-gaap |
Deferred Income Tax Liabilities
DeferredIncomeTaxLiabilities
|
608000 | |
CY2019Q4 | us-gaap |
Deferred Income Tax Liabilities
DeferredIncomeTaxLiabilities
|
714000 | |
CY2020 | us-gaap |
Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
|
40653000 | |
CY2019 | us-gaap |
Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
|
45264000 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards Domestic
DeferredTaxAssetsOperatingLossCarryforwardsDomestic
|
382314000 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards State And Local
DeferredTaxAssetsOperatingLossCarryforwardsStateAndLocal
|
351187000 | |
CY2020Q4 | rytm |
Deferred Tax Assets Operating Loss Carryforwards Indefinite
DeferredTaxAssetsOperatingLossCarryforwardsIndefinite
|
309147000 | |
CY2020Q4 | rytm |
Deferred Tax Assets Tax Credit Carry Forwards Federal Orphan Drug Qualifying Research
DeferredTaxAssetsTaxCreditCarryForwardsFederalOrphanDrugQualifyingResearch
|
10110000 | |
CY2019Q4 | us-gaap |
Income Tax Examination Penalties And Interest Accrued
IncomeTaxExaminationPenaltiesAndInterestAccrued
|
0 | |
CY2020Q4 | us-gaap |
Income Tax Examination Penalties And Interest Accrued
IncomeTaxExaminationPenaltiesAndInterestAccrued
|
0 |