2021 Q4 Form 10-Q Financial Statement
#000155837021014043 Filed on November 02, 2021
Income Statement
Concept | 2021 Q4 | 2021 Q3 | 2020 Q3 |
---|---|---|---|
Revenue | $1.817M | $1.028M | $0.00 |
YoY Change | |||
Cost Of Revenue | $236.0K | $222.0K | |
YoY Change | |||
Gross Profit | $1.581M | $806.0K | |
YoY Change | |||
Gross Profit Margin | 87.01% | 78.4% | |
Selling, General & Admin | $21.00M | $17.51M | $11.29M |
YoY Change | 60.03% | 55.08% | 7.16% |
% of Gross Profit | 1328.02% | 2172.08% | |
Research & Development | $31.57M | $27.54M | $23.00M |
YoY Change | 43.85% | 19.76% | -13.46% |
% of Gross Profit | 1997.09% | 3416.75% | |
Depreciation & Amortization | $325.0K | $315.0K | $170.0K |
YoY Change | 80.56% | 85.29% | -10.53% |
% of Gross Profit | 20.56% | 39.08% | |
Operating Expenses | $52.57M | $45.05M | $34.28M |
YoY Change | 49.9% | 31.39% | -7.61% |
Operating Profit | -$50.99M | -$44.24M | -$34.28M |
YoY Change | 29.04% | -7.61% | |
Interest Expense | $134.0K | $138.0K | $470.0K |
YoY Change | -25.56% | -70.64% | -57.27% |
% of Operating Profit | |||
Other Income/Expense, Net | $0.00 | $138.0K | $466.0K |
YoY Change | -70.39% | -57.79% | |
Pretax Income | -$50.86M | -$44.10M | -$33.82M |
YoY Change | 45.72% | 30.4% | -6.06% |
Income Tax | -$7.989M | -$8.995M | |
% Of Pretax Income | |||
Net Earnings | -$42.87M | -$35.11M | -$33.82M |
YoY Change | 22.83% | 3.81% | -6.07% |
Net Earnings / Revenue | -2359.16% | -3415.08% | |
Basic Earnings Per Share | -$0.70 | ||
Diluted Earnings Per Share | -$852.6K | -$698.7K | -$766.2K |
COMMON SHARES | |||
Basic Shares Outstanding | 50.27M | 50.23M | 44.12M |
Diluted Shares Outstanding | 50.25M |
Balance Sheet
Concept | 2021 Q4 | 2021 Q3 | 2020 Q3 |
---|---|---|---|
SHORT-TERM ASSETS | |||
Cash & Short-Term Investments | $294.9M | $328.4M | $201.8M |
YoY Change | 70.63% | 62.71% | 24.26% |
Cash & Equivalents | $59.25M | $92.37M | $67.67M |
Short-Term Investments | $235.6M | $236.0M | $134.1M |
Other Short-Term Assets | $4.103M | $7.282M | $8.100M |
YoY Change | 34.61% | -10.1% | -3.57% |
Inventory | $111.0K | ||
Prepaid Expenses | |||
Receivables | $1.025M | ||
Other Receivables | $0.00 | ||
Total Short-Term Assets | $308.4M | $335.6M | $209.9M |
YoY Change | 69.75% | 59.89% | 22.83% |
LONG-TERM ASSETS | |||
Property, Plant & Equipment | $2.813M | $2.956M | $3.289M |
YoY Change | -11.96% | -10.12% | -45.18% |
Goodwill | |||
YoY Change | |||
Intangibles | |||
YoY Change | |||
Long-Term Investments | |||
YoY Change | |||
Other Assets | $12.14M | $10.86M | $400.0K |
YoY Change | 2935.75% | 2615.25% | -42.86% |
Total Long-Term Assets | $21.14M | $20.19M | $5.563M |
YoY Change | 291.05% | 262.88% | -15.71% |
TOTAL ASSETS | |||
Total Short-Term Assets | $308.4M | $335.6M | $209.9M |
Total Long-Term Assets | $21.14M | $20.19M | $5.563M |
Total Assets | $329.5M | $355.8M | $215.5M |
YoY Change | 76.15% | 65.13% | 21.4% |
SHORT-TERM LIABILITIES | |||
YoY Change | |||
Accounts Payable | $5.737M | $4.614M | $3.793M |
YoY Change | 17.08% | 21.65% | -50.74% |
Accrued Expenses | $30.08M | $18.27M | $11.54M |
YoY Change | 139.54% | 58.33% | -34.08% |
Deferred Revenue | |||
YoY Change | |||
Short-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Long-Term Debt Due | |||
YoY Change | |||
Total Short-Term Liabilities | $43.43M | $23.47M | $15.85M |
YoY Change | 141.34% | 48.08% | -37.11% |
LONG-TERM LIABILITIES | |||
Long-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Other Long-Term Liabilities | $1.945M | $2.104M | $2.700M |
YoY Change | -25.19% | -22.07% | -15.63% |
Total Long-Term Liabilities | $1.945M | $2.104M | $2.700M |
YoY Change | -25.19% | -22.07% | -15.63% |
TOTAL LIABILITIES | |||
Total Short-Term Liabilities | $43.43M | $23.47M | $15.85M |
Total Long-Term Liabilities | $1.945M | $2.104M | $2.700M |
Total Liabilities | $45.37M | $33.56M | $18.54M |
YoY Change | 120.84% | 81.01% | -34.72% |
SHAREHOLDERS EQUITY | |||
Retained Earnings | -$528.9M | -$486.1M | -$424.4M |
YoY Change | 15.16% | 14.52% | |
Common Stock | $50.00K | $50.00K | $44.00K |
YoY Change | 13.64% | 13.64% | |
Preferred Stock | |||
YoY Change | |||
Treasury Stock (at cost) | |||
YoY Change | |||
Treasury Stock Shares | |||
Shareholders Equity | $284.2M | $322.3M | $196.9M |
YoY Change | |||
Total Liabilities & Shareholders Equity | $329.5M | $355.8M | $215.5M |
YoY Change | 76.15% | 65.13% | 21.4% |
Cashflow Statement
Concept | 2021 Q4 | 2021 Q3 | 2020 Q3 |
---|---|---|---|
OPERATING ACTIVITIES | |||
Net Income | -$42.87M | -$35.11M | -$33.82M |
YoY Change | 22.83% | 3.81% | -6.07% |
Depreciation, Depletion And Amortization | $325.0K | $315.0K | $170.0K |
YoY Change | 80.56% | 85.29% | -10.53% |
Cash From Operating Activities | -$40.47M | -$40.16M | -$27.03M |
YoY Change | 38.98% | 48.58% | -19.58% |
INVESTING ACTIVITIES | |||
Capital Expenditures | -$68.00K | -$106.0K | -$130.0K |
YoY Change | -15.0% | -18.46% | -50.0% |
Acquisitions | |||
YoY Change | |||
Other Investing Activities | $7.316M | $62.89M | $35.04M |
YoY Change | -88.2% | 79.47% | -16.03% |
Cash From Investing Activities | $7.248M | $62.78M | $34.91M |
YoY Change | -88.29% | 79.83% | -15.82% |
FINANCING ACTIVITIES | |||
Cash Dividend Paid | |||
YoY Change | |||
Common Stock Issuance & Retirement, Net | |||
YoY Change | |||
Debt Paid & Issued, Net | |||
YoY Change | |||
Cash From Financing Activities | 100.0K | 413.0K | 700.0K |
YoY Change | -76.19% | -41.0% | 0.0% |
NET CHANGE | |||
Cash From Operating Activities | -40.47M | -40.16M | -27.03M |
Cash From Investing Activities | 7.248M | 62.78M | 34.91M |
Cash From Financing Activities | 100.0K | 413.0K | 700.0K |
Net Change In Cash | -33.12M | 23.03M | 8.580M |
YoY Change | -199.8% | 168.45% | 0.23% |
FREE CASH FLOW | |||
Cash From Operating Activities | -$40.47M | -$40.16M | -$27.03M |
Capital Expenditures | -$68.00K | -$106.0K | -$130.0K |
Free Cash Flow | -$40.40M | -$40.05M | -$26.90M |
YoY Change | 39.13% | 48.9% | -19.34% |
Facts In Submission
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2021-09-30 | ||
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RHYTHM PHARMACEUTICALS, INC. | ||
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DE | ||
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Other Comprehensive Income Loss Available For Sale Securities Adjustment Net Of Tax
OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax
|
-392000 | |
us-gaap |
Other Comprehensive Income Loss Available For Sale Securities Adjustment Net Of Tax
OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax
|
-107000 | ||
us-gaap |
Other Comprehensive Income Loss Available For Sale Securities Adjustment Net Of Tax
OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax
|
238000 | ||
CY2021Q3 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-35107000 | |
CY2020Q3 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-34210000 | |
us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-26853000 | ||
us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-98861000 | ||
CY2020Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
166528000 | |
CY2021Q1 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
5191000 | |
CY2021Q1 | us-gaap |
Stock Issued During Period Value Employee Stock Purchase Plan
StockIssuedDuringPeriodValueEmployeeStockPurchasePlan
|
388000 | |
CY2021Q1 | rytm |
Stock Issued During Period Value Stock Options And Restricted Stock Units Vesting
StockIssuedDuringPeriodValueStockOptionsAndRestrictedStockUnitsVesting
|
3466000 | |
CY2021Q1 | us-gaap |
Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
|
161731000 | |
CY2021Q1 | us-gaap |
Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
|
-107000 | |
CY2021Q1 | us-gaap |
Net Income Loss
NetIncomeLoss
|
43750000 | |
CY2021Q1 | us-gaap |
Stockholders Equity
StockholdersEquity
|
380947000 | |
CY2021Q2 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
5669000 | |
CY2021Q2 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
383000 | |
CY2021Q2 | us-gaap |
Marketable Securities Unrealized Gain Loss
MarketableSecuritiesUnrealizedGainLoss
|
79000 | |
CY2021Q2 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-35389000 | |
CY2021Q2 | us-gaap |
Stockholders Equity
StockholdersEquity
|
351689000 | |
CY2021Q3 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
5268000 | |
CY2021Q3 | us-gaap |
Stock Issued During Period Value Employee Stock Purchase Plan
StockIssuedDuringPeriodValueEmployeeStockPurchasePlan
|
233000 | |
CY2021Q3 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
180000 | |
CY2021Q3 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-35107000 | |
CY2021Q3 | us-gaap |
Stockholders Equity
StockholdersEquity
|
322263000 | |
CY2019Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
281020000 | |
CY2020Q1 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
5475000 | |
CY2020Q1 | us-gaap |
Stock Issued During Period Value Employee Stock Purchase Plan
StockIssuedDuringPeriodValueEmployeeStockPurchasePlan
|
324000 | |
CY2020Q1 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
383000 | |
CY2020Q1 | us-gaap |
Marketable Securities Unrealized Gain Loss
MarketableSecuritiesUnrealizedGainLoss
|
63000 | |
CY2020Q1 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-34164000 | |
CY2020Q1 | us-gaap |
Stockholders Equity
StockholdersEquity
|
253101000 | |
CY2020Q3 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
501000 | |
CY2020Q3 | us-gaap |
Marketable Securities Unrealized Gain Loss
MarketableSecuritiesUnrealizedGainLoss
|
-392000 | |
us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
512000 | ||
rytm |
Deferred Rent Expense
DeferredRentExpense
|
-185000 | ||
CY2020Q2 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
3028000 | |
CY2020Q2 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
174000 | |
CY2020Q2 | us-gaap |
Marketable Securities Unrealized Gain Loss
MarketableSecuritiesUnrealizedGainLoss
|
567000 | |
CY2020Q2 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-31117000 | |
CY2020Q2 | us-gaap |
Stockholders Equity
StockholdersEquity
|
225753000 | |
CY2020Q3 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
4695000 | |
CY2020Q3 | us-gaap |
Stock Issued During Period Value Employee Stock Purchase Plan
StockIssuedDuringPeriodValueEmployeeStockPurchasePlan
|
198000 | |
CY2020Q3 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-33818000 | |
CY2020Q3 | us-gaap |
Stockholders Equity
StockholdersEquity
|
196937000 | |
us-gaap |
Profit Loss
ProfitLoss
|
-26746000 | ||
us-gaap |
Profit Loss
ProfitLoss
|
-99100000 | ||
us-gaap |
Share Based Compensation
ShareBasedCompensation
|
16128000 | ||
us-gaap |
Share Based Compensation
ShareBasedCompensation
|
13198000 | ||
rytm |
Gain On Sale Of Priority Review Voucher
GainOnSaleOfPriorityReviewVoucher
|
100000000 | ||
us-gaap |
Deferred Income Tax Expense Benefit
DeferredIncomeTaxExpenseBenefit
|
7989000 | ||
us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
833000 | ||
rytm |
Deferred Rent Expense
DeferredRentExpense
|
-173000 | ||
us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
-1591000 | ||
us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
-1092000 | ||
us-gaap |
Increase Decrease In Other Noncurrent Assets
IncreaseDecreaseInOtherNoncurrentAssets
|
10533000 | ||
us-gaap |
Increase Decrease In Accounts Payable And Accrued Liabilities
IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
|
5392000 | ||
us-gaap |
Increase Decrease In Accounts Payable And Accrued Liabilities
IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
|
-8387000 | ||
us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-105531000 | ||
us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-92858000 | ||
us-gaap |
Payments To Acquire Short Term Investments
PaymentsToAcquireShortTermInvestments
|
456238000 | ||
us-gaap |
Payments To Acquire Short Term Investments
PaymentsToAcquireShortTermInvestments
|
53398000 | ||
us-gaap |
Proceeds From Maturities Prepayments And Calls Of Shortterm Investments
ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments
|
292197000 | ||
us-gaap |
Proceeds From Maturities Prepayments And Calls Of Shortterm Investments
ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments
|
150172000 | ||
rytm |
Proceeds From Sale Of Priority Review Voucher
ProceedsFromSaleOfPriorityReviewVoucher
|
100000000 | ||
rytm |
Milestone Obligation Under License Agreement
MilestoneObligationUnderLicenseAgreement
|
5000000 | ||
us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
366000 | ||
us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
130000 | ||
us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
-69407000 | ||
us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
96644000 | ||
us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
161731000 | ||
us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
4029000 | ||
us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
1067000 | ||
us-gaap |
Proceeds From Stock Plans
ProceedsFromStockPlans
|
621000 | ||
us-gaap |
Proceeds From Stock Plans
ProceedsFromStockPlans
|
522000 | ||
us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
166381000 | ||
us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
1589000 | ||
us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
-8557000 | ||
us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
5375000 | ||
CY2020Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
|
101257000 | |
CY2019Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
|
62697000 | |
CY2021Q3 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
|
92700000 | |
CY2020Q3 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
|
68072000 | |
us-gaap |
Nature Of Operations
NatureOfOperations
|
<p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:center;text-indent:0pt;margin:0pt 0pt 12pt 0pt;"><b style="font-weight:bold;">Rhythm Pharmaceuticals, Inc.</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin-bottom:12pt;margin-left:0pt;margin-top:0pt;overflow:hidden;position:relative;"><span style="padding-bottom:2.0pt;padding-right:2.0pt;position:relative;text-indent:0pt;z-index:1;background:white;"><span style="display:inline-block;width:20.86%;"> </span><b style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-style:normal;font-weight:bold;text-align:left;">Notes to Unaudited Condensed Consolidated Financial Statements</b></span><span style="display:block;height:1px;position:absolute;width:100%;z-index:0;"></span><span style="float:right;padding-left:2.0pt;position:relative;text-indent:0pt;z-index:1;background:white;"/></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:center;text-indent:0pt;margin:0pt 0pt 12pt 0pt;"><b style="font-weight:bold;white-space:pre-wrap;"> (In thousands, except share and per share information)</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-weight:bold;margin:0pt 0pt 12pt 0pt;">1. Nature of Business</p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;text-indent:36pt;margin:0pt 0pt 12pt 0pt;">Rhythm Pharmaceuticals, Inc. (the “Company” or “we”) is a commercial-stage biopharmaceutical company focused on changing the paradigm for the treatment of rare genetic diseases of obesity, which are characterized by early-onset, severe obesity and an insatiable hunger or hyperphagia. Our lead product candidate is IMCIVREE<sup style="font-size:7.5pt;line-height:100%;top:0pt;vertical-align:top;">®</sup> (setmelanotide), a potent melanocortin-4 receptor, or MC4R, agonist for the treatment of rare genetic diseases of obesity. We believe IMCIVREE, for which we have exclusive worldwide rights, has the potential to restore dysfunctional MC4R signaling due to impaired MC4R pathway function. MC4R pathway deficiencies result in the disruption of satiety signals and energy homeostasis in the body, which, in turn, leads to intense feelings of hunger and to obesity. IMCIVREE has been approved by the U.S. Food and Drug Administration, or FDA, for chronic weight management in adult and pediatric patients six years of age and older with obesity due to proopiomelanocortin, or POMC, proprotein convertase subtilisin/kexin type 1, or PCSK1, or leptin receptor, or LEPR, deficiency confirmed by genetic testing. IMCIVREE also has been approved by the European Commission for the treatment of obesity and the control of hunger associated with genetically confirmed loss-of-function biallelic POMC, including PCSK1, deficiency or biallelic LEPR deficiency in adults and children 6 years of age and above. IMCIVREE is now commercially available in the United States, and we are pursuing an international strategy to establish access and reimbursement for IMCIVREE in the European Union, or EU, and Great Britain. We also have completed and submitted a supplemental New Drug Application, or sNDA, to the U.S. Food and Drug Administration or FDA, and a Type II variation marketing authorization application, or MAA, to the EMA for IMCIVREE for the treatment of obesity and control of hunger in adult and pediatric patients 6 years of age and older with Bardet-Biedl syndrome, or BBS, or Alström syndrome. </p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;text-indent:36pt;margin:0pt 0pt 12pt 0pt;">The Company is a Delaware corporation organized in February 2013 under the name Rhythm Metabolic, Inc., and as of October 2015, under the name Rhythm Pharmaceuticals, Inc. </p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;text-indent:36pt;margin:0pt 0pt 12pt 0pt;">The Company’s continued development efforts are focused on obesity related to several single gene-related, or monogenic, MC4R pathway deficiencies: Bardet-Biedl and Alstrom syndromes; obesity due to a genetic variant in one of the two alleles of the POMC, PCSK1 or LEPR gene, or heterozygous POMC, PCSK1 or LEPR obesity (collectively HETs); obesity due to steroid receptor coactivator 1, or SRC1, deficiency; obesity due to SH2B adapter protein 1, or SH2B1, deficiency; hypothalamic obesity; and MC4R deficiency obesity. In addition, we have expanded our development program to explore setmelotide’s potential efficacy in patients with severe obesity which may be due to variants in an additional 31 genes that are related to the MC4R pathway. There are additional diseases being studied as part of investigator-initiated protocols. Currently, there are no effective or approved treatments for these MC4R pathway-related diseases. The Company believes that the MC4R pathway is a compelling target for treating these genetic diseases because of its critical role in regulating appetite and weight by promoting satiety and weight control, and that peptide therapeutics are uniquely suited for activating this target. </p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;text-indent:36pt;margin:0pt 0pt 12pt 0pt;"> <span style="background-color:#ffffff;">The Company is subject to risks and uncertainties common to commercial-stage companies in the biotechnology industry, including but not limited to risks associated with the commercialization of approved products, completing preclinical studies and clinical trials, receiving regulatory approvals for product candidates, development by competitors of new biopharmaceutical products, dependence on key personnel, protection of proprietary technology, compliance with government regulations and the ability to secure additional capital to fund operations. Commercialization of approved products will require significant resources and in order to market IMCIVREE, the Company must continue to build its sales, marketing, managerial and other non-technical capabilities or make arrangements with third parties to perform these services. Product candidates currently under development will require significant additional research and development efforts, including preclinical and clinical testing and regulatory approval, prior to commercialization. These efforts require significant amounts of additional capital, adequate personnel and infrastructure and extensive compliance-reporting capabilities. </span></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-style:italic;font-weight:bold;margin:0pt 0pt 12pt 0pt;">Liquidity</p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;text-indent:36pt;margin:0pt 0pt 12pt 0pt;">The Company has incurred operating losses and negative cash flows from operations since inception. As of September 30, 2021, the Company had an accumulated deficit of $486,073. The Company has primarily funded these losses through the proceeds from the sales of common and preferred stock, asset sales as well as capital contributions received from the former parent company, Rhythm Holdings LLC. To date, the Company has minimal product revenue and management expects operating losses to continue for the foreseeable future. The Company has devoted substantially all of its resources to its drug development efforts, comprising of research and development, manufacturing, conducting clinical trials for its product candidates, protecting its intellectual property, pre-commercialization activities and general and administrative functions relating to these operations. The future success of the Company is dependent on its ability to develop its product candidates and ultimately upon its ability to attain profitable operations.</p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;text-indent:36pt;margin:0pt 0pt 12pt 0pt;">In February 2021, the Company completed the sale of a Rare Pediatric Disease Priority Review Voucher, or PRV, that it received in connection with the approval of IMCIVREE for $100,000. As the PRV did not have a carrying value, the gain recognized within Other income (loss) was equal to the gross proceeds received, with costs related to the sale of the voucher recorded within selling, general and administrative expenses. </p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;text-indent:36pt;margin:0pt 0pt 12pt 0pt;">At September 30, 2021, the Company had $328,354 of cash and cash equivalents and short-term investments on hand. In the future, the Company will be dependent on obtaining funding from third parties, such as proceeds from the issuance of debt, sale of equity, product sales and funded research and development programs to maintain the Company's operations and meet the Company's obligations. There is no guarantee that additional equity or other financings will be available to the Company on acceptable terms, or at all. If the Company fails to obtain additional funding when needed, the Company would be forced to scale back, terminate its operations or seek to merge with or be acquired by another company. Management believes that the Company's existing cash resources will be sufficient to fund the Company's operations into at least the second half of 2023.</p> | ||
CY2021Q3 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-486073000 | |
CY2021Q1 | rytm |
Proceeds From Sale Of Priority Review Voucher
ProceedsFromSaleOfPriorityReviewVoucher
|
100000000 | |
CY2021Q3 | us-gaap |
Cash Cash Equivalents And Short Term Investments
CashCashEquivalentsAndShortTermInvestments
|
328354000 | |
CY2020Q1 | us-gaap |
Marketable Securities Unrealized Gain Loss
MarketableSecuritiesUnrealizedGainLoss
|
63000 | |
us-gaap |
Use Of Estimates
UseOfEstimates
|
<p style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-style:italic;font-weight:bold;margin:0pt 0pt 12pt 0pt;">Use of Estimates</p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;text-indent:36pt;margin:0pt 0pt 12pt 0pt;">The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent liabilities at the date of the financial statements and the reported amounts of revenue and expenses during the reporting period. The Company bases its estimates on historical experience and other market-specific or other relevant assumptions that it believes to be reasonable under the circumstances. This process may result in actual results differing materially from those estimated amounts used in the preparation of the financial statements if these results differ from historical experience, or other assumptions do not turn out to be substantially accurate, even if such assumptions are reasonable when made. Significant estimates relied upon in preparing these financial statements include accruals related to research and development expenses, assumptions used to record stock-based compensation expense and the valuation allowance on the Company's deferred tax assets. Estimates are periodically reviewed in light of changes in circumstances, facts and experience. Changes in estimates are recorded in the period in which they become known. Actual results could differ materially from those estimates.</p> | ||
rytm |
Number Of Federally Insured Financial Institutions
NumberOfFederallyInsuredFinancialInstitutions
|
2 | ||
rytm |
Number Of Federally Insured Financial Institutions
NumberOfFederallyInsuredFinancialInstitutions
|
2 | ||
us-gaap |
Number Of Operating Segments
NumberOfOperatingSegments
|
1 | ||
us-gaap |
Number Of Reportable Segments
NumberOfReportableSegments
|
1 | ||
rytm |
Revenue Performance Obligation Payment Terms
RevenuePerformanceObligationPaymentTerms
|
P45D | ||
CY2021Q3 | us-gaap |
Revenue From Contract With Customer Including Assessed Tax
RevenueFromContractWithCustomerIncludingAssessedTax
|
1028000 | |
us-gaap |
Revenue From Contract With Customer Including Assessed Tax
RevenueFromContractWithCustomerIncludingAssessedTax
|
1337000 | ||
rytm |
Accounts Receivable Terms
AccountsReceivableTerms
|
P45D | ||
us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
5275914 | ||
CY2021Q3 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
6406621 | |
CY2020Q3 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
5275914 | |
us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
6406621 | ||
CY2021Q3 | rytm |
Accrued Research And Development Costs
AccruedResearchAndDevelopmentCosts
|
8943000 | |
CY2020Q4 | rytm |
Accrued Research And Development Costs
AccruedResearchAndDevelopmentCosts
|
5815000 | |
CY2021Q3 | us-gaap |
Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
|
2560000 | |
CY2020Q4 | us-gaap |
Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
|
648000 | |
CY2021Q3 | rytm |
Accrued Payroll Related Expense Current
AccruedPayrollRelatedExpenseCurrent
|
6008000 | |
CY2020Q4 | rytm |
Accrued Payroll Related Expense Current
AccruedPayrollRelatedExpenseCurrent
|
5916000 | |
CY2021Q3 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
754000 | |
CY2020Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
180000 | |
CY2021Q3 | us-gaap |
Accrued Liabilities Current
AccruedLiabilitiesCurrent
|
18265000 | |
CY2020Q4 | us-gaap |
Accrued Liabilities Current
AccruedLiabilitiesCurrent
|
12559000 | |
CY2021Q3 | us-gaap |
Cash Cash Equivalents And Short Term Investments
CashCashEquivalentsAndShortTermInvestments
|
328354000 | |
CY2020Q4 | us-gaap |
Cash Cash Equivalents And Short Term Investments
CashCashEquivalentsAndShortTermInvestments
|
172792000 | |
CY2021Q3 | us-gaap |
Available For Sale Debt Securities Amortized Cost Basis
AvailableForSaleDebtSecuritiesAmortizedCostBasis
|
235961000 | |
CY2021Q3 | us-gaap |
Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
|
29000 | |
CY2021Q3 | us-gaap |
Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
|
8000 | |
CY2021Q3 | us-gaap |
Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
|
235982000 | |
CY2020Q4 | us-gaap |
Available For Sale Debt Securities Amortized Cost Basis
AvailableForSaleDebtSecuritiesAmortizedCostBasis
|
71895000 | |
CY2020Q4 | us-gaap |
Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
|
43000 | |
CY2020Q4 | us-gaap |
Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
|
71938000 | |
CY2021Q3 | us-gaap |
Lessee Operating Lease Remaining Lease Term
LesseeOperatingLeaseRemainingLeaseTerm
|
P3Y9M18D | |
CY2021Q3 | us-gaap |
Lessee Operating Lease Discount Rate
LesseeOperatingLeaseDiscountRate
|
0.10 | |
CY2021Q3 | us-gaap |
Lessee Operating Lease Term Of Contract
LesseeOperatingLeaseTermOfContract
|
P6Y | |
CY2021Q3 | us-gaap |
Lessee Operating Lease Renewal Term
LesseeOperatingLeaseRenewalTerm
|
P5Y | |
us-gaap |
Lessee Operating Lease Existence Of Option To Extend
LesseeOperatingLeaseExistenceOfOptionToExtend
|
true | ||
CY2021Q3 | us-gaap |
Lessee Operating Lease Renewal Term
LesseeOperatingLeaseRenewalTerm
|
P5Y | |
CY2021Q3 | us-gaap |
Lessee Operating Lease Liability Payments Remainder Of Fiscal Year
LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear
|
203000 | |
CY2021Q3 | us-gaap |
Lessee Operating Lease Liability Payments Due Next Twelve Months
LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
|
818000 | |
CY2021Q3 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Two
LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
|
834000 | |
CY2021Q3 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Three
LesseeOperatingLeaseLiabilityPaymentsDueYearThree
|
851000 | |
CY2021Q3 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Four
LesseeOperatingLeaseLiabilityPaymentsDueYearFour
|
502000 | |
CY2021Q3 | us-gaap |
Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
|
3208000 | |
CY2021Q3 | us-gaap |
Lessee Operating Lease Liability Undiscounted Excess Amount
LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
|
516000 | |
CY2021Q3 | us-gaap |
Operating Lease Liability
OperatingLeaseLiability
|
2692000 | |
CY2021Q3 | us-gaap |
Finite Lived Intangible Assets Amortization Expense Year Four
FiniteLivedIntangibleAssetsAmortizationExpenseYearFour
|
455000 | |
CY2021Q3 | rytm |
Finite Lived Intangible Asset Expected Amortization After Year Four
FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour
|
2838000 | |
CY2021Q3 | us-gaap |
Finite Lived Intangible Assets Net
FiniteLivedIntangibleAssetsNet
|
4772000 | |
CY2021Q3 | us-gaap |
Finite Lived Intangible Assets Net
FiniteLivedIntangibleAssetsNet
|
4772000 | |
CY2021Q3 | us-gaap |
Finite Lived Intangible Assets Amortization Expense Remainder Of Fiscal Year
FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear
|
114000 | |
CY2021Q3 | us-gaap |
Finite Lived Intangible Assets Amortization Expense Next Twelve Months
FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths
|
455000 | |
CY2021Q3 | us-gaap |
Finite Lived Intangible Assets Amortization Expense Year Two
FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo
|
455000 | |
CY2021Q3 | us-gaap |
Finite Lived Intangible Assets Amortization Expense Year Three
FiniteLivedIntangibleAssetsAmortizationExpenseYearThree
|
455000 | |
us-gaap |
Finite Lived Intangible Assets Remaining Amortization Period1
FiniteLivedIntangibleAssetsRemainingAmortizationPeriod1
|
P11Y | ||
CY2021Q3 | us-gaap |
Amortization Of Intangible Assets
AmortizationOfIntangibleAssets
|
114000 | |
us-gaap |
Amortization Of Intangible Assets
AmortizationOfIntangibleAssets
|
228000 | ||
CY2021Q3 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
-8995000 | |
us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
7989000 | ||
CY2021Q1 | us-gaap |
Stock Issued During Period Shares New Issues
StockIssuedDuringPeriodSharesNewIssues
|
5750000 | |
CY2021Q1 | us-gaap |
Share Price
SharePrice
|
30.00 | |
CY2021Q1 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
161731000 | |
us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Accelerated Compensation Cost
ShareBasedCompensationArrangementByShareBasedPaymentAwardAcceleratedCompensationCost
|
2811000 |