2021 Form 10-K Financial Statement

#000155837022003452 Filed on March 11, 2022

View on sec.gov

Income Statement

Concept 2021 2020 Q4 2020
Revenue $2.113M $600.0K $2.948M
YoY Change -28.33% -70.0% -3.32%
Cost Of Revenue
YoY Change
Gross Profit
YoY Change
Gross Profit Margin
Selling, General & Admin $16.83M $3.280M $14.93M
YoY Change 12.68% 47.09% 58.35%
% of Gross Profit
Research & Development $18.82M $4.190M $12.94M
YoY Change 45.46% 27.36% -0.57%
% of Gross Profit
Depreciation & Amortization $607.7K $90.00K $333.2K
YoY Change 82.4% 80.0% 43.29%
% of Gross Profit
Operating Expenses $37.53M $7.630M $29.07M
YoY Change 29.1% 41.3% 26.08%
Operating Profit -$35.42M -$26.12M
YoY Change 35.58%
Interest Expense $838.1K $340.0K -$512.2K
YoY Change -263.62% 466.67% -218.62%
% of Operating Profit
Other Income/Expense, Net -$127.7K $130.0K -$257.0K
YoY Change -50.3% 160.0% 905.58%
Pretax Income -$35.55M -$6.550M -$26.38M
YoY Change 34.74% 99.09% 29.7%
Income Tax -$146.0K $0.00 $0.00
% Of Pretax Income
Net Earnings -$35.07M -$6.450M -$26.05M
YoY Change 34.63% 93.11% 30.13%
Net Earnings / Revenue -1659.95% -1075.0% -883.65%
Basic Earnings Per Share -$1.41 -$1.63
Diluted Earnings Per Share -$1.49 -$0.29 -$1.63
COMMON SHARES
Basic Shares Outstanding 24.91M 15.98M
Diluted Shares Outstanding 24.91M 15.98M

Balance Sheet

Concept 2021 2020 Q4 2020
SHORT-TERM ASSETS
Cash & Short-Term Investments $96.38M $111.8M $111.8M
YoY Change -13.77% 655.41% 657.6%
Cash & Equivalents $8.054M $10.93M $10.93M
Short-Term Investments $88.32M $100.8M $100.8M
Other Short-Term Assets $2.887M $1.800M $1.843M
YoY Change 56.65% 350.0% 338.37%
Inventory
Prepaid Expenses
Receivables $66.05K $177.2K $177.2K
Other Receivables $0.00 $0.00 $0.00
Total Short-Term Assets $99.33M $113.8M $113.8M
YoY Change -12.71% 648.65% 648.2%
LONG-TERM ASSETS
Property, Plant & Equipment $4.412M $676.3K $2.959M
YoY Change 49.09% -77.46% -2.48%
Goodwill $1.452M
YoY Change
Intangibles
YoY Change
Long-Term Investments
YoY Change
Other Assets $12.40M $9.724M $122.8K
YoY Change 9998.91% 2331.05% -68.89%
Total Long-Term Assets $21.63M $10.40M $10.40M
YoY Change 107.97% -3.7% -3.23%
TOTAL ASSETS
Total Short-Term Assets $99.33M $113.8M $113.8M
Total Long-Term Assets $21.63M $10.40M $10.40M
Total Assets $121.0M $124.2M $124.2M
YoY Change -2.6% 377.67% 378.47%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable $922.8K $1.052M $1.052M
YoY Change -12.26% -29.88% -30.04%
Accrued Expenses $2.770M $1.615M $1.893M
YoY Change 46.31% -15.02% 0.0%
Deferred Revenue $603.7K
YoY Change
Short-Term Debt $0.00 $0.00 $0.00
YoY Change
Long-Term Debt Due $260.6K $100.0K $108.1K
YoY Change 140.98% 120.22%
Total Short-Term Liabilities $4.721M $3.657M $3.657M
YoY Change 29.09% -56.47% -56.65%
LONG-TERM LIABILITIES
Long-Term Debt $255.4K $200.0K $160.2K
YoY Change 59.4% 100.0% 12.32%
Other Long-Term Liabilities $3.736M $36.24K $4.522M
YoY Change -17.39% -99.07% 17.18%
Total Long-Term Liabilities $3.991M $36.24K $4.682M
YoY Change -14.76% -99.09% 17.01%
TOTAL LIABILITIES
Total Short-Term Liabilities $4.721M $3.657M $3.657M
Total Long-Term Liabilities $3.991M $36.24K $4.682M
Total Liabilities $7.853M $8.701M $7.955M
YoY Change -1.29% -29.83% -35.77%
SHAREHOLDERS EQUITY
Retained Earnings -$130.6M
YoY Change
Common Stock $4.519K
YoY Change
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity $113.1M $116.2M $116.2M
YoY Change
Total Liabilities & Shareholders Equity $121.0M $124.2M $124.2M
YoY Change -2.6% 377.67% 378.47%

Cashflow Statement

Concept 2021 2020 Q4 2020
OPERATING ACTIVITIES
Net Income -$35.07M -$6.450M -$26.05M
YoY Change 34.63% 93.11% 30.13%
Depreciation, Depletion And Amortization $607.7K $90.00K $333.2K
YoY Change 82.4% 80.0% 43.29%
Cash From Operating Activities -$38.13M -$6.440M -$22.02M
YoY Change 73.15% 2476.0% 71.54%
INVESTING ACTIVITIES
Capital Expenditures $1.905M $20.00K $338.0K
YoY Change 463.57% -84.62% -227.45%
Acquisitions
YoY Change
Other Investing Activities $11.67M -$8.340M -$95.08M
YoY Change -112.28% -10525.0% 329929.43%
Cash From Investing Activities $9.770M -$8.360M -$95.42M
YoY Change -110.24% 20800.0% 32355.59%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net $26.30M $117.4M
YoY Change -77.59% 558289.61%
Debt Paid & Issued, Net
YoY Change
Cash From Financing Activities 25.49M 920.0K 119.3M
YoY Change -78.64% 626299.25%
NET CHANGE
Cash From Operating Activities -38.13M -6.440M -22.02M
Cash From Investing Activities 9.770M -8.360M -95.42M
Cash From Financing Activities 25.49M 920.0K 119.3M
Net Change In Cash -2.878M -13.88M 1.892M
YoY Change -252.11% 4686.21% -114.43%
FREE CASH FLOW
Cash From Operating Activities -$38.13M -$6.440M -$22.02M
Capital Expenditures $1.905M $20.00K $338.0K
Free Cash Flow -$40.03M -$6.460M -$22.36M
YoY Change 79.05% 1600.0% 77.84%

Facts In Submission

Frame Concept Type Concept / XBRL Key Value Unit
CY2021Q4 us-gaap Commitments And Contingencies
CommitmentsAndContingencies
CY2020Q4 us-gaap Commitments And Contingencies
CommitmentsAndContingencies
CY2020 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-1.63
CY2020 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
15982568
CY2021Q4 us-gaap Goodwill Gross
GoodwillGross
CY2021 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
24913942
CY2020 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
15982568
CY2021 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-1.49
CY2020 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-1.63
CY2020Q4 us-gaap Preferred Stock Shares Outstanding
PreferredStockSharesOutstanding
0
CY2021Q4 us-gaap Preferred Stock Shares Outstanding
PreferredStockSharesOutstanding
0
CY2020Q4 us-gaap Common Stock Shares Issued
CommonStockSharesIssued
22832428
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice
12.12
CY2021Q4 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1
37130
CY2021 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1
P8Y2M19D
CY2021Q4 us-gaap Common Stock Shares Outstanding
CommonStockSharesOutstanding
25649824
CY2021Q4 us-gaap Common Stock Shares Issued
CommonStockSharesIssued
25649824
CY2021 dei Entity Central Index Key
EntityCentralIndexKey
0001476963
CY2021 dei Current Fiscal Year End Date
CurrentFiscalYearEndDate
--12-31
CY2021 dei Document Fiscal Year Focus
DocumentFiscalYearFocus
2021
CY2021 dei Document Fiscal Period Focus
DocumentFiscalPeriodFocus
FY
CY2021 dei Amendment Flag
AmendmentFlag
false
CY2021 dei Security Exchange Name
SecurityExchangeName
NASDAQ
CY2020 us-gaap Goodwill Impairment Loss
GoodwillImpairmentLoss
0
CY2020Q4 us-gaap Stockholders Equity Note Stock Split Conversion Ratio1
StockholdersEquityNoteStockSplitConversionRatio1
0.1429
CY2020Q4 us-gaap Common Stock Shares Outstanding
CommonStockSharesOutstanding
22800000
CY2020Q4 us-gaap Common Stock Shares Issued
CommonStockSharesIssued
159800000
CY2020Q4 us-gaap Stockholders Equity Note Stock Split Conversion Ratio1
StockholdersEquityNoteStockSplitConversionRatio1
0.1429
CY2020Q4 us-gaap Common Stock Shares Outstanding
CommonStockSharesOutstanding
22832428
CY2020 htbx Decrease In Tax Credit Carryforward Valuation Allowance
DecreaseInTaxCreditCarryforwardValuationAllowance
3000000
CY2021 dei Document Type
DocumentType
10-K
CY2021 dei Document Annual Report
DocumentAnnualReport
true
CY2021 dei Document Period End Date
DocumentPeriodEndDate
2021-12-31
CY2021 dei Document Transition Report
DocumentTransitionReport
false
CY2021 dei Entity File Number
EntityFileNumber
001-35994
CY2021 dei Entity Registrant Name
EntityRegistrantName
HEAT BIOLOGICS, INC.
CY2021 dei Entity Incorporation State Country Code
EntityIncorporationStateCountryCode
DE
CY2021 dei Entity Tax Identification Number
EntityTaxIdentificationNumber
26-2844103
CY2021 dei Entity Address Address Line1
EntityAddressAddressLine1
627 Davis Drive, Suite 400
CY2021 dei Entity Address City Or Town
EntityAddressCityOrTown
Morrisville
CY2021 dei Entity Address State Or Province
EntityAddressStateOrProvince
NC
CY2021 dei Entity Address Postal Zip Code
EntityAddressPostalZipCode
27560
CY2021 dei City Area Code
CityAreaCode
919
CY2021 dei Local Phone Number
LocalPhoneNumber
240-7133
CY2021 dei Security12b Title
Security12bTitle
Common Stock, $0.0002 par value per share
CY2021 dei Trading Symbol
TradingSymbol
HTBX
CY2021 dei Entity Well Known Seasoned Issuer
EntityWellKnownSeasonedIssuer
No
CY2021 dei Entity Voluntary Filers
EntityVoluntaryFilers
No
CY2021 dei Entity Current Reporting Status
EntityCurrentReportingStatus
Yes
CY2021 dei Entity Interactive Data Current
EntityInteractiveDataCurrent
Yes
CY2021 dei Entity Filer Category
EntityFilerCategory
Non-accelerated Filer
CY2021 dei Entity Small Business
EntitySmallBusiness
true
CY2021 dei Entity Emerging Growth Company
EntityEmergingGrowthCompany
false
CY2021 dei Icfr Auditor Attestation Flag
IcfrAuditorAttestationFlag
false
CY2021 dei Entity Shell Company
EntityShellCompany
false
CY2021Q2 dei Entity Public Float
EntityPublicFloat
169016850
CY2022Q1 dei Entity Common Stock Shares Outstanding
EntityCommonStockSharesOutstanding
25649824
CY2021 dei Auditor Name
AuditorName
BDO USA, LLP
CY2021 dei Auditor Location
AuditorLocation
Raleigh, NC
CY2021 dei Auditor Firm
AuditorFirmId
243
CY2021Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
8053879
CY2020Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
10931890
CY2021Q4 us-gaap Short Term Investments
ShortTermInvestments
88324922
CY2020Q4 us-gaap Short Term Investments
ShortTermInvestments
100842438
CY2021Q4 us-gaap Accounts Receivable Net Current
AccountsReceivableNetCurrent
66049
CY2020Q4 us-gaap Accounts Receivable Net Current
AccountsReceivableNetCurrent
177239
CY2021Q4 us-gaap Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
2886520
CY2020Q4 us-gaap Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
1842620
CY2021Q4 us-gaap Assets Current
AssetsCurrent
99331370
CY2020Q4 us-gaap Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
0.0002
CY2021Q4 us-gaap Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
0.0002
CY2021Q4 us-gaap Common Stock Shares Authorized
CommonStockSharesAuthorized
250000000
CY2020Q4 us-gaap Assets Current
AssetsCurrent
113794187
CY2021Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
2158479
CY2020Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
676262
CY2021Q4 us-gaap Finite Lived Intangible Assets Net
FiniteLivedIntangibleAssetsNet
3500000
CY2020Q4 us-gaap Finite Lived Intangible Assets Net
FiniteLivedIntangibleAssetsNet
5866000
CY2020Q4 us-gaap Goodwill
Goodwill
1452338
CY2021Q4 us-gaap Grants Receivable Noncurrent
GrantsReceivableNoncurrent
1318359
CY2021Q4 us-gaap Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
1782884
CY2020Q4 us-gaap Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
2035882
CY2021Q4 us-gaap Finance Lease Right Of Use Asset
FinanceLeaseRightOfUseAsset
470700
CY2020Q4 us-gaap Finance Lease Right Of Use Asset
FinanceLeaseRightOfUseAsset
247194
CY2021Q4 us-gaap Other Assets Miscellaneous Noncurrent
OtherAssetsMiscellaneousNoncurrent
12193540
CY2021Q4 us-gaap Deposits Assets Noncurrent
DepositsAssetsNoncurrent
205901
CY2020Q4 us-gaap Deposits Assets Noncurrent
DepositsAssetsNoncurrent
122779
CY2021Q4 us-gaap Other Assets Noncurrent
OtherAssetsNoncurrent
19471384
CY2020Q4 us-gaap Other Assets Noncurrent
OtherAssetsNoncurrent
9724193
CY2021Q4 us-gaap Assets
Assets
120961233
CY2020Q4 us-gaap Assets
Assets
124194642
CY2021Q4 us-gaap Accounts Payable Current
AccountsPayableCurrent
922782
CY2020Q4 us-gaap Accounts Payable Current
AccountsPayableCurrent
1051764
CY2020Q4 us-gaap Contract With Customer Liability Current
ContractWithCustomerLiabilityCurrent
603717
CY2021Q4 us-gaap Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
350343
CY2020Q4 us-gaap Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
278753
CY2021Q4 us-gaap Finance Lease Liability Current
FinanceLeaseLiabilityCurrent
260574
CY2020Q4 us-gaap Finance Lease Liability Current
FinanceLeaseLiabilityCurrent
108127
CY2021Q4 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
2419676
CY2020Q4 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
1614534
CY2021Q4 us-gaap Business Combination Contingent Consideration Liability Current
BusinessCombinationContingentConsiderationLiabilityCurrent
593037
CY2021Q4 htbx Business Combination Contingent Consideration Liability Related Party Current
BusinessCombinationContingentConsiderationLiabilityRelatedPartyCurrent
174333
CY2021Q4 us-gaap Liabilities Current
LiabilitiesCurrent
4720745
CY2020Q4 us-gaap Liabilities Current
LiabilitiesCurrent
3656895
CY2021Q4 us-gaap Other Liabilities Noncurrent
OtherLiabilitiesNoncurrent
53530
CY2020Q4 us-gaap Other Liabilities Noncurrent
OtherLiabilitiesNoncurrent
36243
CY2021Q4 us-gaap Derivative Liabilities Noncurrent
DerivativeLiabilitiesNoncurrent
11020
CY2020Q4 us-gaap Derivative Liabilities Noncurrent
DerivativeLiabilitiesNoncurrent
33779
CY2021Q4 us-gaap Deferred Income Tax Liabilities Net
DeferredIncomeTaxLiabilitiesNet
215937
CY2020Q4 us-gaap Deferred Income Tax Liabilities Net
DeferredIncomeTaxLiabilitiesNet
361911
CY2021Q4 us-gaap Contract With Customer Liability Noncurrent
ContractWithCustomerLiabilityNoncurrent
35000
CY2020Q4 us-gaap Contract With Customer Liability Noncurrent
ContractWithCustomerLiabilityNoncurrent
237500
CY2021Q4 us-gaap Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
1060856
CY2020Q4 us-gaap Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
1301636
CY2021Q4 us-gaap Finance Lease Liability Noncurrent
FinanceLeaseLiabilityNoncurrent
255429
CY2020Q4 us-gaap Finance Lease Liability Noncurrent
FinanceLeaseLiabilityNoncurrent
160240
CY2021Q4 us-gaap Business Combination Contingent Consideration Liability Noncurrent
BusinessCombinationContingentConsiderationLiabilityNoncurrent
1990118
CY2020Q4 us-gaap Business Combination Contingent Consideration Liability Noncurrent
BusinessCombinationContingentConsiderationLiabilityNoncurrent
2250844
CY2021Q4 htbx Business Combination Contingent Consideration Liability Related Party Noncurrent
BusinessCombinationContingentConsiderationLiabilityRelatedPartyNoncurrent
585027
CY2020Q4 htbx Business Combination Contingent Consideration Liability Related Party Noncurrent
BusinessCombinationContingentConsiderationLiabilityRelatedPartyNoncurrent
661671
CY2021Q4 us-gaap Liabilities
Liabilities
8927662
CY2020Q4 us-gaap Liabilities
Liabilities
8700719
CY2020Q4 us-gaap Common Stock Shares Authorized
CommonStockSharesAuthorized
250000000
CY2021Q4 us-gaap Common Stock Shares Outstanding
CommonStockSharesOutstanding
25649824
CY2020Q4 us-gaap Common Stock Shares Issued
CommonStockSharesIssued
22832428
CY2021Q4 us-gaap Common Stock Value
CommonStockValue
5055
CY2020Q4 us-gaap Common Stock Value
CommonStockValue
4519
CY2021Q4 us-gaap Additional Paid In Capital
AdditionalPaidInCapital
278890153
CY2020Q4 us-gaap Additional Paid In Capital
AdditionalPaidInCapital
247048349
CY2021Q4 us-gaap Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
-165718953
CY2020Q4 us-gaap Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
-130647485
CY2021Q4 us-gaap Accumulated Other Comprehensive Income Loss Net Of Tax
AccumulatedOtherComprehensiveIncomeLossNetOfTax
-67941
CY2020Q4 us-gaap Accumulated Other Comprehensive Income Loss Net Of Tax
AccumulatedOtherComprehensiveIncomeLossNetOfTax
-166056
CY2021Q4 us-gaap Stockholders Equity
StockholdersEquity
113108314
CY2020Q4 us-gaap Stockholders Equity
StockholdersEquity
116239327
CY2021Q4 us-gaap Minority Interest
MinorityInterest
-1074743
CY2020Q4 us-gaap Minority Interest
MinorityInterest
-745404
CY2021Q4 us-gaap Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
112033571
CY2020Q4 us-gaap Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
115493923
CY2021Q4 us-gaap Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
120961233
CY2020Q4 us-gaap Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
124194642
CY2021 us-gaap Revenue From Contract With Customer Including Assessed Tax
RevenueFromContractWithCustomerIncludingAssessedTax
2112806
CY2020 us-gaap Revenue From Contract With Customer Including Assessed Tax
RevenueFromContractWithCustomerIncludingAssessedTax
2947969
CY2021 us-gaap Research And Development Expense
ResearchAndDevelopmentExpense
18821278
CY2020 us-gaap Research And Development Expense
ResearchAndDevelopmentExpense
12938895
CY2021 us-gaap General And Administrative Expense
GeneralAndAdministrativeExpense
16828229
CY2020 us-gaap General And Administrative Expense
GeneralAndAdministrativeExpense
14934436
CY2021 us-gaap Goodwill Impairment Loss
GoodwillImpairmentLoss
1452338
CY2021 htbx Change In Fair Value Of Contingent Consideration
ChangeInFairValueOfContingentConsideration
430000
CY2020 htbx Change In Fair Value Of Contingent Consideration
ChangeInFairValueOfContingentConsideration
1199000
CY2021 us-gaap Operating Expenses
OperatingExpenses
37531845
CY2020 us-gaap Operating Expenses
OperatingExpenses
29072331
CY2021 us-gaap Operating Income Loss
OperatingIncomeLoss
-35419039
CY2020 us-gaap Operating Income Loss
OperatingIncomeLoss
-26124362
CY2021 us-gaap Fair Value Adjustment Of Warrants
FairValueAdjustmentOfWarrants
-22758
CY2020 us-gaap Fair Value Adjustment Of Warrants
FairValueAdjustmentOfWarrants
1012167
CY2020 htbx Noncash Investor Relations Expense
NoncashInvestorRelationsExpense
66767
CY2021 us-gaap Interest Income Other
InterestIncomeOther
815316
CY2020 us-gaap Interest Income Other
InterestIncomeOther
566718
CY2021 us-gaap Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
-965816
CY2020 us-gaap Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
255189
CY2021 us-gaap Nonoperating Income Expense
NonoperatingIncomeExpense
-127742
CY2020 us-gaap Nonoperating Income Expense
NonoperatingIncomeExpense
-257027
CY2021 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-35546781
CY2020 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-26381389
CY2021 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
-145974
CY2021 us-gaap Profit Loss
ProfitLoss
-35400807
CY2020 us-gaap Profit Loss
ProfitLoss
-26381389
CY2021 us-gaap Net Income Loss Attributable To Noncontrolling Interest
NetIncomeLossAttributableToNoncontrollingInterest
-329339
CY2020 us-gaap Net Income Loss Attributable To Noncontrolling Interest
NetIncomeLossAttributableToNoncontrollingInterest
-331652
CY2021 us-gaap Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1
EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1
P1Y6M25D
CY2020 us-gaap Fair Value Adjustment Of Warrants
FairValueAdjustmentOfWarrants
1012167
CY2021 us-gaap Net Income Loss
NetIncomeLoss
-35071468
CY2020 us-gaap Net Income Loss
NetIncomeLoss
-26049737
CY2021 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-1.41
CY2020 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-1.63
CY2021 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
24913942
CY2020 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
15982568
CY2021 us-gaap Profit Loss
ProfitLoss
-35400807
CY2020 us-gaap Profit Loss
ProfitLoss
-26381389
CY2021 us-gaap Other Comprehensive Income Loss Foreign Currency Transaction And Translation Adjustment Net Of Tax
OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
98115
CY2020 us-gaap Other Comprehensive Income Loss Foreign Currency Transaction And Translation Adjustment Net Of Tax
OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax
-154806
CY2021 us-gaap Comprehensive Income Net Of Tax Including Portion Attributable To Noncontrolling Interest
ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest
-35302692
CY2020 us-gaap Comprehensive Income Net Of Tax Including Portion Attributable To Noncontrolling Interest
ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest
-26536195
CY2021 us-gaap Comprehensive Income Net Of Tax Attributable To Noncontrolling Interest
ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest
-329339
CY2020 us-gaap Comprehensive Income Net Of Tax Attributable To Noncontrolling Interest
ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest
-331652
CY2021 us-gaap Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
-34973353
CY2020 us-gaap Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
-26204543
CY2019Q4 us-gaap Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
13157850
CY2020 htbx Stock Issued During Period Value New Issues1
StockIssuedDuringPeriodValueNewIssues1
4106149
CY2020 htbx Stock Issued During Period Value New Issues2
StockIssuedDuringPeriodValueNewIssues2
117373495
CY2020 us-gaap Adjustments To Additional Paid In Capital Stock Issued Issuance Costs
AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts
3103833
CY2020 us-gaap Stock Granted During Period Value Sharebased Compensation
StockGrantedDuringPeriodValueSharebasedCompensation
6377857
CY2020 htbx Exercise Of Warrants Amounts
ExerciseOfWarrantsAmounts
3442322
CY2020 htbx Exchange Of Warrants Amount
ExchangeOfWarrantsAmount
773330
CY2020 htbx Adjustments To Additional Paid In Capital Cash Paid In Lieu Of Fractional Shares
AdjustmentsToAdditionalPaidInCapitalCashPaidInLieuOfFractionalShares
97052
CY2020 us-gaap Other Comprehensive Income Loss Net Of Tax
OtherComprehensiveIncomeLossNetOfTax
-154806
CY2020 us-gaap Profit Loss
ProfitLoss
-26381389
CY2020Q4 us-gaap Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
115493923
CY2021 htbx Stock Issued During Period Value New Issues2
StockIssuedDuringPeriodValueNewIssues2
26304282
CY2021 us-gaap Adjustments To Additional Paid In Capital Stock Issued Issuance Costs
AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts
658184
CY2021 us-gaap Stock Granted During Period Value Sharebased Compensation
StockGrantedDuringPeriodValueSharebasedCompensation
6168981
CY2021 us-gaap Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
27261
CY2021 us-gaap Other Comprehensive Income Loss Net Of Tax
OtherComprehensiveIncomeLossNetOfTax
98115
CY2021 us-gaap Profit Loss
ProfitLoss
-35400807
CY2021Q4 us-gaap Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
112033571
CY2021 us-gaap Profit Loss
ProfitLoss
-35400807
CY2020 us-gaap Profit Loss
ProfitLoss
-26381389
CY2021 us-gaap Goodwill Impairment Loss
GoodwillImpairmentLoss
1452338
CY2021 us-gaap Impairment Of Intangible Assets Finitelived
ImpairmentOfIntangibleAssetsFinitelived
2366000
CY2021 us-gaap Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
607667
CY2020 us-gaap Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
333152
CY2021 htbx Noncash Lease Expense
NoncashLeaseExpense
83809
CY2020 htbx Noncash Lease Expense
NoncashLeaseExpense
95600
CY2021 htbx Noncash Interest Expense
NoncashInterestExpense
21970
CY2020 htbx Noncash Interest Expense
NoncashInterestExpense
17972
CY2020 htbx Noncash Investor Relations Expense
NoncashInvestorRelationsExpense
66767
CY2021 us-gaap Share Based Compensation
ShareBasedCompensation
6168981
CY2020 us-gaap Share Based Compensation
ShareBasedCompensation
6377857
CY2021 us-gaap Fair Value Adjustment Of Warrants
FairValueAdjustmentOfWarrants
-22758
CY2021 htbx Change In Fair Value Of Contingent Consideration
ChangeInFairValueOfContingentConsideration
430000
CY2020 htbx Change In Fair Value Of Contingent Consideration
ChangeInFairValueOfContingentConsideration
1199000
CY2021 us-gaap Unrealized Gain Loss On Investments
UnrealizedGainLossOnInvestments
-842538
CY2020 us-gaap Unrealized Gain Loss On Investments
UnrealizedGainLossOnInvestments
44871
CY2021 us-gaap Increase Decrease In Accounts Receivable
IncreaseDecreaseInAccountsReceivable
-110111
CY2020 us-gaap Increase Decrease In Accounts Receivable
IncreaseDecreaseInAccountsReceivable
140559
CY2021 us-gaap Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
1060915
CY2020 us-gaap Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
1419395
CY2021 htbx Increase Decrease In Grants Receivable
IncreaseDecreaseInGrantsReceivable
1318359
CY2021 htbx Increase Decrease In Other Assets Miscellaneous Noncurrent
IncreaseDecreaseInOtherAssetsMiscellaneousNoncurrent
12193540
CY2021 us-gaap Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
-126937
CY2020 us-gaap Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
-452778
CY2021 us-gaap Increase Decrease In Accrued Liabilities And Other Operating Liabilities
IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities
929023
CY2020 us-gaap Increase Decrease In Accrued Liabilities And Other Operating Liabilities
IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities
-223882
CY2021 us-gaap Increase Decrease In Deferred Revenue
IncreaseDecreaseInDeferredRevenue
-806217
CY2020 us-gaap Increase Decrease In Deferred Revenue
IncreaseDecreaseInDeferredRevenue
-2769101
CY2021 us-gaap Increase Decrease In Deferred Liabilities
IncreaseDecreaseInDeferredLiabilities
-145974
CY2021 us-gaap Increase Decrease In Other Noncurrent Liabilities
IncreaseDecreaseInOtherNoncurrentLiabilities
17286
CY2020 us-gaap Increase Decrease In Other Noncurrent Liabilities
IncreaseDecreaseInOtherNoncurrentLiabilities
36243
CY2021 htbx Increase Decrease In Deposits Operating Activity
IncreaseDecreaseInDepositsOperatingActivity
-83122
CY2020 htbx Increase Decrease In Deposits Operating Activity
IncreaseDecreaseInDepositsOperatingActivity
271858
CY2021 us-gaap Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
-38128906
CY2020 us-gaap Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
-22021359
CY2021 us-gaap Payments To Acquire Short Term Investments
PaymentsToAcquireShortTermInvestments
66960279
CY2020 us-gaap Payments To Acquire Short Term Investments
PaymentsToAcquireShortTermInvestments
105925802
CY2021 us-gaap Proceeds From Sale Maturity And Collection Of Shortterm Investments
ProceedsFromSaleMaturityAndCollectionOfShorttermInvestments
78635257
CY2020 us-gaap Proceeds From Sale Maturity And Collection Of Shortterm Investments
ProceedsFromSaleMaturityAndCollectionOfShorttermInvestments
10842157
CY2021 us-gaap Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
1904713
CY2020 us-gaap Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
337972
CY2020 us-gaap Proceeds From Sale Of Property Plant And Equipment
ProceedsFromSaleOfPropertyPlantAndEquipment
2168
CY2021 us-gaap Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
9770265
CY2020 us-gaap Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
-95419449
CY2020 us-gaap Proceeds From Issuance Initial Public Offering
ProceedsFromIssuanceInitialPublicOffering
6600971
CY2021 us-gaap Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
26304282
CY2020 us-gaap Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
117373495
CY2021 us-gaap Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
27261
CY2020 us-gaap Proceeds From Warrant Exercises
ProceedsFromWarrantExercises
675675
CY2021 us-gaap Payments Of Stock Issuance Costs
PaymentsOfStockIssuanceCosts
658184
CY2020 us-gaap Payments Of Stock Issuance Costs
PaymentsOfStockIssuanceCosts
3103833
CY2020 htbx Payment For Fractional Shares From Reverse Stock Split Financing Activities
PaymentForFractionalSharesFromReverseStockSplitFinancingActivities
97052
CY2020 us-gaap Payment For Contingent Consideration Liability Financing Activities
PaymentForContingentConsiderationLiabilityFinancingActivities
2005000
CY2020 htbx Proceeds From Paycheck Protection Program Loans
ProceedsFromPaycheckProtectionProgramLoans
702000
CY2020 htbx Repayments Of Paycheck Protection Program Loans
RepaymentsOfPaycheckProtectionProgramLoans
702000
CY2021 us-gaap Finance Lease Principal Payments
FinanceLeasePrincipalPayments
183010
CY2020 us-gaap Finance Lease Principal Payments
FinanceLeasePrincipalPayments
115199
CY2021 us-gaap Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
25490349
CY2020 us-gaap Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
119329057
CY2021 us-gaap Effect Of Exchange Rate On Cash And Cash Equivalents
EffectOfExchangeRateOnCashAndCashEquivalents
-9719
CY2020 us-gaap Effect Of Exchange Rate On Cash And Cash Equivalents
EffectOfExchangeRateOnCashAndCashEquivalents
3754
CY2020 htbx Common Shares Issued In Exchange For Warrants
CommonSharesIssuedInExchangeForWarrants
319756
CY2021Q4 us-gaap Business Combination Contingent Consideration Liability
BusinessCombinationContingentConsiderationLiability
3342515
CY2021 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
-2878011
CY2020 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
1892003
CY2020Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
10931890
CY2019Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
9039887
CY2021Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
8053879
CY2020Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
10931890
CY2021 us-gaap Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
88596
CY2020 us-gaap Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
75244
CY2021 htbx Right Of Use Asset Obtained In Exchange For Operating Lease Liability Modifications
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiabilityModifications
37767
CY2021 us-gaap Right Of Use Asset Obtained In Exchange For Finance Lease Liability
RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability
408677
CY2020 us-gaap Right Of Use Asset Obtained In Exchange For Finance Lease Liability
RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability
173822
CY2020 htbx Proceeds From Proceeds Allocated To Warrant Liability
ProceedsFromProceedsAllocatedToWarrantLiability
2494823
CY2020 htbx Cashless Exercise Of Warrants Classified As Liabilities
CashlessExerciseOfWarrantsClassifiedAsLiabilities
2766647
CY2020 htbx Cashless Exchange Of Warrants Classified As Liabilities
CashlessExchangeOfWarrantsClassifiedAsLiabilities
773330
CY2021Q4 us-gaap Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
-165700000
CY2021 us-gaap Profit Loss
ProfitLoss
-35400000
CY2021Q4 us-gaap Cash Cash Equivalents And Short Term Investments
CashCashEquivalentsAndShortTermInvestments
96400000
CY2021 us-gaap Use Of Estimates
UseOfEstimates
<p style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-style:italic;font-weight:bold;text-align:justify;margin:0pt 0pt 12pt 0pt;">Use of Estimates</p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;margin:0pt 0pt 12pt 0pt;">The preparation of financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the amounts reported in the financial statements and accompanying notes. Estimates are used for, but not limited to, useful lives of fixed assets, contingent consideration, valuation of goodwill and in process research and development (“IPR&amp;D”), income taxes, valuation of warrant liabilities, and stock-based compensation. Actual results may differ from those estimates.</p>
CY2021 us-gaap Prior Period Reclassification Adjustment Description
PriorPeriodReclassificationAdjustmentDescription
<p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"><span style="font-style:italic;font-weight:bold;">Immaterial Revision</span></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"><span style="font-size:13.5pt;font-style:italic;visibility:hidden;">​</span></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;">During the course of preparing the Company’s consolidated financial statements as of and for the year ended December 31 2021, the Company completed an Internal Revenue Code Section 382 and 383 analysis of its historical net operating loss and tax credit carryforward amounts. As a result, a portion of the prior year net operating loss and tax credit carryforwards were limited and incorrectly presented in the deferred tax table within Note 12. See Note 12—Income Taxes, for further details.</p>
CY2021 us-gaap Prior Period Reclassification Adjustment Description
PriorPeriodReclassificationAdjustmentDescription
<p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"><span style="font-style:italic;font-weight:bold;">Immaterial Revision</span></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"><span style="font-size:13.5pt;font-style:italic;visibility:hidden;">​</span></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;">During the course of preparing the Company’s consolidated financial statements as of and for the year ended December 31 2021, the Company completed an Internal Revenue Code Section 382 and 383 analysis of its historical net operating loss and tax credit carryforward amounts. As a result, a portion of the prior year net operating loss and tax credit carryforwards were limited and incorrectly presented in the deferred tax table within Note 12. See Note 12—Income Taxes, for further details.</p>
CY2020 htbx Percentage Of Revenue Generated In United States
PercentageOfRevenueGeneratedInUnitedStates
1
CY2021 htbx Percentage Of Revenue Generated In United States
PercentageOfRevenueGeneratedInUnitedStates
1
CY2021 us-gaap Number Of Reportable Segments
NumberOfReportableSegments
1
CY2021 us-gaap Concentration Risk Credit Risk
ConcentrationRiskCreditRisk
<p style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-style:italic;font-weight:bold;text-align:justify;margin:0pt 0pt 12pt 0pt;">Concentration of Credit Risk</p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;margin:0pt 0pt 12pt 0pt;">At times, cash balances may exceed the Federal Deposit Insurance Corporation (“FDIC”) insurable limits. The Company has never experienced any losses related to these balances. As of December 31, 2021, and 2020, cash amounts in excess of $250,000 were not fully insured. The uninsured cash balance as of December 31, 2021 was $7,500,658. The Company does not believe it is exposed to significant credit risk on cash and cash equivalents.</p>
CY2020Q4 us-gaap Cash Fdic Insured Amount
CashFDICInsuredAmount
250000
CY2021Q4 us-gaap Cash Fdic Insured Amount
CashFDICInsuredAmount
250000
CY2021Q4 us-gaap Cash Uninsured Amount
CashUninsuredAmount
7500658
CY2021Q4 us-gaap Derivative Liabilities Noncurrent
DerivativeLiabilitiesNoncurrent
11020
CY2020Q4 us-gaap Derivative Liabilities Noncurrent
DerivativeLiabilitiesNoncurrent
33779
CY2021Q4 us-gaap Other Assets Miscellaneous Noncurrent
OtherAssetsMiscellaneousNoncurrent
12200000
CY2021Q4 us-gaap Derivative Liabilities Noncurrent
DerivativeLiabilitiesNoncurrent
11020
CY2021Q4 us-gaap Short Term Investments
ShortTermInvestments
88324922
CY2020Q4 us-gaap Short Term Investments
ShortTermInvestments
100842438
CY2020Q4 us-gaap Business Combination Contingent Consideration Liability
BusinessCombinationContingentConsiderationLiability
2912515
CY2020Q4 us-gaap Derivative Liabilities Noncurrent
DerivativeLiabilitiesNoncurrent
33779
CY2019Q4 us-gaap Business Combination Contingent Consideration Liability
BusinessCombinationContingentConsiderationLiability
3718515
CY2020 htbx Warrant Fair Value At Issuance
WarrantFairValueAtIssuance
2494823
CY2020 htbx Reclassification Of Warrants From Equity To Liability Due To Modification
ReclassificationOfWarrantsFromEquityToLiabilityDueToModification
869078
CY2020 htbx Warrant Liability Reclassification To Equity
WarrantLiabilityReclassificationToEquity
2766647
CY2020 htbx Reclassification Of Warrant Liability To Equity Upon Exchange Of Warrants
ReclassificationOfWarrantLiabilityToEquityUponExchangeOfWarrants
1575642
CY2020 us-gaap Payment For Contingent Consideration Liability Financing Activities
PaymentForContingentConsiderationLiabilityFinancingActivities
2005000
CY2020 htbx Change In Fair Value Of Contingent Consideration
ChangeInFairValueOfContingentConsideration
1199000
CY2020 us-gaap Fair Value Adjustment Of Warrants
FairValueAdjustmentOfWarrants
1012167
CY2020Q4 us-gaap Business Combination Contingent Consideration Liability
BusinessCombinationContingentConsiderationLiability
2912515
CY2020Q4 us-gaap Derivative Liabilities Noncurrent
DerivativeLiabilitiesNoncurrent
33779
CY2021 htbx Change In Fair Value Of Contingent Consideration
ChangeInFairValueOfContingentConsideration
430000
CY2021 us-gaap Fair Value Adjustment Of Warrants
FairValueAdjustmentOfWarrants
-22758
CY2021Q4 us-gaap Business Combination Contingent Consideration Liability
BusinessCombinationContingentConsiderationLiability
3342515
CY2021Q4 us-gaap Derivative Liabilities Noncurrent
DerivativeLiabilitiesNoncurrent
11020
CY2021 htbx Change In Fair Value Of Contingent Consideration
ChangeInFairValueOfContingentConsideration
430000
CY2020 htbx Change In Fair Value Of Contingent Consideration
ChangeInFairValueOfContingentConsideration
1199000
CY2021 htbx Fair Value Measurements Valuation Technique
FairValueMeasurementsValuationTechnique
Probability weighted income approach
CY2021 htbx Fair Value Measurements Significant Unobservable Input Milestone Dates
FairValueMeasurementsSignificantUnobservableInputMilestoneDates
2022-2031
CY2021 htbx Fair Value Inputs Discount Rate1
FairValueInputsDiscountRate1
0.0751
CY2021 htbx Fair Value Inputs Probability Of Occurrence Minimum
FairValueInputsProbabilityOfOccurrenceMinimum
0.049
CY2021 htbx Fair Value Inputs Probability Of Occurrence Maximum
FairValueInputsProbabilityOfOccurrenceMaximum
0.75
CY2020 htbx Fair Value Measurements Valuation Technique
FairValueMeasurementsValuationTechnique
Probability weighted income approach
CY2020 htbx Fair Value Measurements Significant Unobservable Input Milestone Dates
FairValueMeasurementsSignificantUnobservableInputMilestoneDates
2022-2030
CY2020 htbx Fair Value Inputs Discount Rate1
FairValueInputsDiscountRate1
0.0766
CY2020 htbx Fair Value Inputs Probability Of Occurrence Minimum
FairValueInputsProbabilityOfOccurrenceMinimum
0.027
CY2020 htbx Fair Value Inputs Probability Of Occurrence Maximum
FairValueInputsProbabilityOfOccurrenceMaximum
0.68
CY2020Q4 us-gaap Goodwill Gross
GoodwillGross
1500000
CY2021 us-gaap Goodwill Impairment Loss
GoodwillImpairmentLoss
1500000
CY2020Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
0
CY2021Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
0
CY2020Q4 us-gaap Equity Method Investment Ownership Percentage
EquityMethodInvestmentOwnershipPercentage
0.15
CY2021Q4 us-gaap Equity Method Investment Ownership Percentage
EquityMethodInvestmentOwnershipPercentage
0.15
CY2021Q4 us-gaap Grants Receivable
GrantsReceivable
1300000
CY2021 htbx Amount Of Allowable Expenses Incurred Under Grant
AmountOfAllowableExpensesIncurredUnderGrant
100000
CY2021Q4 us-gaap Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
1000000.0
CY2020Q4 us-gaap Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
200000
CY2021Q4 htbx Prepaid Manufacturing Expense
PrepaidManufacturingExpense
563280
CY2020Q4 htbx Prepaid Manufacturing Expense
PrepaidManufacturingExpense
316411
CY2021Q4 us-gaap Prepaid Insurance
PrepaidInsurance
704650
CY2020Q4 us-gaap Prepaid Insurance
PrepaidInsurance
612293
CY2021Q4 htbx Prepaid Preclinical And Clinical Expenses
PrepaidPreclinicalAndClinicalExpenses
1158560
CY2020Q4 htbx Prepaid Preclinical And Clinical Expenses
PrepaidPreclinicalAndClinicalExpenses
690543
CY2021Q4 us-gaap Other Prepaid Expense Current
OtherPrepaidExpenseCurrent
460030
CY2020Q4 us-gaap Other Prepaid Expense Current
OtherPrepaidExpenseCurrent
223373
CY2021Q4 us-gaap Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
2886520
CY2020Q4 us-gaap Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
1842620
CY2021Q4 us-gaap Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
3662215
CY2020Q4 us-gaap Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
1765382
CY2021Q4 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
1503736
CY2020Q4 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
1089120
CY2021Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
2158479
CY2020Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
676262
CY2021 us-gaap Depreciation
Depreciation
422496
CY2020 us-gaap Depreciation
Depreciation
218951
CY2021Q4 us-gaap Goodwill Impaired Accumulated Impairment Loss
GoodwillImpairedAccumulatedImpairmentLoss
2200000
CY2020Q4 us-gaap Goodwill Impaired Accumulated Impairment Loss
GoodwillImpairedAccumulatedImpairmentLoss
700000
CY2020Q4 us-gaap Goodwill Gross
GoodwillGross
1500000
CY2020 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Terms Of Award
ShareBasedCompensationArrangementByShareBasedPaymentAwardTermsOfAward
P10Y
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Terms Of Award
ShareBasedCompensationArrangementByShareBasedPaymentAwardTermsOfAward
P10Y
CY2021 us-gaap Goodwill Impairment Loss
GoodwillImpairmentLoss
1500000
CY2020Q4 us-gaap Finite Lived Intangible Assets Net
FiniteLivedIntangibleAssetsNet
5900000
CY2021Q4 us-gaap Finite Lived Intangible Assets Fair Value Disclosure
FiniteLivedIntangibleAssetsFairValueDisclosure
3500000
CY2021 us-gaap Impairment Of Intangible Assets Finitelived
ImpairmentOfIntangibleAssetsFinitelived
2400000
CY2020Q4 us-gaap Goodwill Gross
GoodwillGross
1452338
CY2021 us-gaap Goodwill Impairment Loss
GoodwillImpairmentLoss
1452338
CY2021Q4 htbx Accrued Clinical Trial Expense Current
AccruedClinicalTrialExpenseCurrent
955013
CY2020Q4 htbx Accrued Clinical Trial Expense Current
AccruedClinicalTrialExpenseCurrent
628000
CY2021Q4 htbx Accrued Manufacturing Expenses
AccruedManufacturingExpenses
179173
CY2020Q4 htbx Accrued Manufacturing Expenses
AccruedManufacturingExpenses
175089
CY2021Q4 us-gaap Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
459178
CY2020Q4 us-gaap Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
209600
CY2021Q4 htbx Accrued Franchise Tax
AccruedFranchiseTax
195000
CY2020Q4 htbx Accrued Franchise Tax
AccruedFranchiseTax
172500
CY2021Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
631312
CY2020Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
429345
CY2021Q4 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
2419676
CY2020Q4 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
1614534
CY2021Q4 htbx Future Minimum Royalty Payments Due In Three Years
FutureMinimumRoyaltyPaymentsDueInThreeYears
775000000
CY2021Q4 htbx Future Minimum Royalty Payments Due Current
FutureMinimumRoyaltyPaymentsDueCurrent
34000000
CY2021Q4 htbx Future Minimum Royalty Payments Due In Two Years
FutureMinimumRoyaltyPaymentsDueInTwoYears
74000000
CY2021Q4 htbx Future Minimum Royalty Payments Due In Four Years
FutureMinimumRoyaltyPaymentsDueInFourYears
25000000
CY2021Q4 htbx Future Minimum Royalty Payments Due In Five Years
FutureMinimumRoyaltyPaymentsDueInFiveYears
50000000
CY2021Q4 htbx Future Minimum Royalty Payments Due
FutureMinimumRoyaltyPaymentsDue
958000000
CY2021 us-gaap Share Based Compensation
ShareBasedCompensation
6168981
CY2021 us-gaap Employee Service Share Based Compensation Allocation Of Recognized Period Costs Capitalized Amount
EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsCapitalizedAmount
0
CY2021Q4 us-gaap Grants Receivable Noncurrent
GrantsReceivableNoncurrent
1300000
CY2020Q4 us-gaap Preferred Stock Shares Authorized
PreferredStockSharesAuthorized
10000000
CY2021Q4 us-gaap Preferred Stock Shares Authorized
PreferredStockSharesAuthorized
10000000
CY2020Q4 us-gaap Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
0.0001
CY2021Q4 us-gaap Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
0.0001
CY2020Q4 us-gaap Preferred Stock Shares Issued
PreferredStockSharesIssued
0
CY2021Q4 us-gaap Preferred Stock Shares Issued
PreferredStockSharesIssued
0
CY2020Q4 us-gaap Common Stock Shares Authorized
CommonStockSharesAuthorized
250000000
CY2021Q4 us-gaap Common Stock Shares Authorized
CommonStockSharesAuthorized
250000000
CY2020Q4 us-gaap Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
0.0002
CY2021Q4 us-gaap Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
0.0002
CY2020Q1 us-gaap Common Stock Shares Authorized
CommonStockSharesAuthorized
250000000
CY2020Q4 us-gaap Common Stock Shares Outstanding
CommonStockSharesOutstanding
159800000
CY2020Q4 us-gaap Common Stock Shares Issued
CommonStockSharesIssued
22800000
CY2021Q4 us-gaap Common Stock Shares Issued
CommonStockSharesIssued
25649824
CY2020Q4 us-gaap Common Stock Shares Outstanding
CommonStockSharesOutstanding
22832428
CY2020 us-gaap Share Based Compensation
ShareBasedCompensation
6377857
CY2021 us-gaap Share Based Compensation
ShareBasedCompensation
6168981
CY2020 us-gaap Share Based Compensation
ShareBasedCompensation
6377857
CY2020 us-gaap Employee Service Share Based Compensation Allocation Of Recognized Period Costs Capitalized Amount
EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsCapitalizedAmount
0
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
0
CY2020 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
0
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
3.67
CY2020 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
5.92
CY2019Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
437603
CY2019Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
17.90
CY2019Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
44196
CY2020 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
1167749
CY2020 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
7.90
CY2020 us-gaap Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
7140
CY2020 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
3.99
CY2020 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
9813
CY2020 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Expirations In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod
118073
CY2020 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Expirations In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice
5.80
CY2020Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
1480139
CY2020Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
11.05
CY2020Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
9213
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
1674153
CY2021 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
4.65
CY2021 us-gaap Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
70967
CY2021 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
6.53
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Expirations In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod
49532
CY2021 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Expirations In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice
14.26
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod
79478
CY2021 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice
5.55
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
2954315
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
7.62
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
100419
CY2021 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
P9Y7D
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber
1161021
CY2021Q4 us-gaap Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Stock Options
EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions
5900000
CY2020 htbx Effective Income Tax Rate Reconciliation Nondeductible Expense Executive Compensation Amount
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseExecutiveCompensationAmount
248000
CY2020 htbx Income Tax Reconciliation Nondeductible Expense Payout Of Contingent Consideration
IncomeTaxReconciliationNondeductibleExpensePayoutOfContingentConsideration
421000
CY2021 us-gaap Income Tax Reconciliation Nondeductible Expense Impairment Losses
IncomeTaxReconciliationNondeductibleExpenseImpairmentLosses
305000
CY2021 htbx Income Tax Reconciliation Reserve For Loss Carryforwards Limited By Section382
IncomeTaxReconciliationReserveForLossCarryforwardsLimitedBySection382
8000
CY2020 htbx Income Tax Reconciliation Reserve For Loss Carryforwards Limited By Section382
IncomeTaxReconciliationReserveForLossCarryforwardsLimitedBySection382
15270000
CY2020Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
0
CY2021Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
0
CY2020Q4 us-gaap Unrecognized Tax Benefits That Would Impact Effective Tax Rate
UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate
0
CY2021Q4 us-gaap Unrecognized Tax Benefits That Would Impact Effective Tax Rate
UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate
0
CY2020Q4 us-gaap Unrecognized Tax Benefits Income Tax Penalties And Interest Accrued
UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued
0
CY2021Q4 us-gaap Unrecognized Tax Benefits Income Tax Penalties And Interest Accrued
UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued
0
CY2021 us-gaap Deferred Federal Income Tax Expense Benefit
DeferredFederalIncomeTaxExpenseBenefit
-145974
CY2021 us-gaap Income Tax Expense Benefit Intraperiod Tax Allocation
IncomeTaxExpenseBenefitIntraperiodTaxAllocation
-145974
CY2020 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
0.21
CY2021 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
0.21
CY2021 us-gaap Income Tax Reconciliation Income Tax Expense Benefit At Federal Statutory Income Tax Rate
IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate
-7465000
CY2020 us-gaap Income Tax Reconciliation Income Tax Expense Benefit At Federal Statutory Income Tax Rate
IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate
-5540000
CY2021 us-gaap Income Tax Reconciliation State And Local Income Taxes
IncomeTaxReconciliationStateAndLocalIncomeTaxes
556000
CY2020 us-gaap Income Tax Reconciliation State And Local Income Taxes
IncomeTaxReconciliationStateAndLocalIncomeTaxes
833000
CY2021 us-gaap Income Tax Reconciliation Foreign Income Tax Rate Differential
IncomeTaxReconciliationForeignIncomeTaxRateDifferential
-16000
CY2020 us-gaap Income Tax Reconciliation Foreign Income Tax Rate Differential
IncomeTaxReconciliationForeignIncomeTaxRateDifferential
5000
CY2021 us-gaap Income Tax Reconciliation Nondeductible Expense
IncomeTaxReconciliationNondeductibleExpense
1000
CY2020 us-gaap Income Tax Reconciliation Nondeductible Expense
IncomeTaxReconciliationNondeductibleExpense
210000
CY2021 htbx Income Tax Reconciliation Nondeductible Expense Research And Development Expense
IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentExpense
-836000
CY2020 htbx Income Tax Reconciliation Nondeductible Expense Research And Development Expense
IncomeTaxReconciliationNondeductibleExpenseResearchAndDevelopmentExpense
-682000
CY2021 us-gaap Income Tax Reconciliation Nondeductible Expense Share Based Compensation Cost
IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost
164000
CY2020 us-gaap Income Tax Reconciliation Nondeductible Expense Share Based Compensation Cost
IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost
113000
CY2021 htbx Effective Income Tax Rate Reconciliation Nondeductible Expense Executive Compensation Amount
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseExecutiveCompensationAmount
259000
CY2021 us-gaap Income Tax Reconciliation Other Reconciling Items
IncomeTaxReconciliationOtherReconcilingItems
-32974
CY2020 us-gaap Income Tax Reconciliation Other Reconciling Items
IncomeTaxReconciliationOtherReconcilingItems
-41000
CY2021 us-gaap Income Tax Reconciliation Change In Deferred Tax Assets Valuation Allowance
IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance
6911000
CY2020 us-gaap Income Tax Reconciliation Change In Deferred Tax Assets Valuation Allowance
IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance
-10837000
CY2021 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
-145974
CY2021Q4 us-gaap Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
17830889
CY2020Q4 us-gaap Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
13012193
CY2021Q4 us-gaap Deferred Tax Assets In Process Research And Development
DeferredTaxAssetsInProcessResearchAndDevelopment
2538168
CY2020Q4 us-gaap Deferred Tax Assets In Process Research And Development
DeferredTaxAssetsInProcessResearchAndDevelopment
1528044
CY2021Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Compensation And Benefits
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits
2344902
CY2020Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Compensation And Benefits
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits
1931784
CY2021Q4 htbx Deferred Tax Assets Contingent Consideration
DeferredTaxAssetsContingentConsideration
767763
CY2020Q4 htbx Deferred Tax Assets Contingent Consideration
DeferredTaxAssetsContingentConsideration
668994
CY2021Q4 us-gaap Deferred Tax Assets Deferred Income
DeferredTaxAssetsDeferredIncome
8039
CY2021Q4 htbx Deferred Tax Assets Unrealized Gains Losses
DeferredTaxAssetsUnrealizedGainsLosses
210300
CY2021Q4 us-gaap Deferred Tax Assets Net
DeferredTaxAssetsNet
23700061
CY2020Q4 us-gaap Deferred Tax Assets Net
DeferredTaxAssetsNet
17141015
CY2021Q4 us-gaap Deferred Tax Liabilities Goodwill And Intangible Assets Intangible Assets
DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets
803937
CY2020Q4 us-gaap Deferred Tax Liabilities Goodwill And Intangible Assets Intangible Assets
DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets
1347399
CY2021Q4 us-gaap Deferred Tax Liabilities Property Plant And Equipment
DeferredTaxLiabilitiesPropertyPlantAndEquipment
83122
CY2020Q4 us-gaap Deferred Tax Liabilities Property Plant And Equipment
DeferredTaxLiabilitiesPropertyPlantAndEquipment
69882
CY2021Q4 htbx Deferred Tax Liabilities Lease Liability
DeferredTaxLiabilitiesLeaseLiability
78035
CY2020Q4 htbx Deferred Tax Liabilities Lease Liability
DeferredTaxLiabilitiesLeaseLiability
99761
CY2021Q4 us-gaap Deferred Tax Liabilities Other
DeferredTaxLiabilitiesOther
83931
CY2020Q4 us-gaap Deferred Tax Liabilities Other
DeferredTaxLiabilitiesOther
29781
CY2021Q4 us-gaap Deferred Income Tax Liabilities
DeferredIncomeTaxLiabilities
1049025
CY2020Q4 us-gaap Deferred Income Tax Liabilities
DeferredIncomeTaxLiabilities
1546823
CY2021Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
22866973
CY2020Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
15956103
CY2021Q4 us-gaap Deferred Tax Liabilities
DeferredTaxLiabilities
215937
CY2020Q4 us-gaap Deferred Tax Liabilities
DeferredTaxLiabilities
361911
CY2019Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
32484566
CY2020Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
15956103
CY2021Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
22866973
CY2020Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
0
CY2021Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
0
CY2020Q4 us-gaap Unrecognized Tax Benefits That Would Impact Effective Tax Rate
UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate
0
CY2021Q4 us-gaap Unrecognized Tax Benefits That Would Impact Effective Tax Rate
UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate
0
CY2020Q4 us-gaap Unrecognized Tax Benefits Income Tax Penalties And Interest Accrued
UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued
0
CY2021Q4 us-gaap Unrecognized Tax Benefits Income Tax Penalties And Interest Accrued
UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued
0
CY2020 htbx Decrease In Deferred Tax Assets Operating Loss Carryforwards Total
DecreaseInDeferredTaxAssetsOperatingLossCarryforwardsTotal
13500000
CY2020 htbx Reduction In Tax Credit Carryforward Amount
ReductionInTaxCreditCarryforwardAmount
3000000
CY2020Q4 htbx Overstatement Of Gross Deferred Tax Asset And Valuation Allowance
OverstatementOfGrossDeferredTaxAssetAndValuationAllowance
16500000
CY2021 us-gaap Operating Lease Payments
OperatingLeasePayments
400000
CY2020 us-gaap Operating Lease Payments
OperatingLeasePayments
300000
CY2021 htbx Leases Effective Interest Rate Percent
LeasesEffectiveInterestRatePercent
0.0552
CY2020 htbx Leases Effective Interest Rate Percent
LeasesEffectiveInterestRatePercent
0.0617
CY2021 us-gaap Operating Lease Cost
OperatingLeaseCost
474135
CY2020 us-gaap Operating Lease Cost
OperatingLeaseCost
435024
CY2021 us-gaap Finance Lease Right Of Use Asset Amortization
FinanceLeaseRightOfUseAssetAmortization
185171
CY2020 us-gaap Finance Lease Right Of Use Asset Amortization
FinanceLeaseRightOfUseAssetAmortization
114201
CY2021 us-gaap Finance Lease Interest Expense
FinanceLeaseInterestExpense
21970
CY2020 us-gaap Finance Lease Interest Expense
FinanceLeaseInterestExpense
17972
CY2021 us-gaap Lease Cost
LeaseCost
207141
CY2020 us-gaap Lease Cost
LeaseCost
132173
CY2021Q4 us-gaap Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
P5Y
CY2020Q4 us-gaap Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
P5Y10M24D
CY2021Q4 us-gaap Finance Lease Weighted Average Remaining Lease Term1
FinanceLeaseWeightedAverageRemainingLeaseTerm1
P2Y
CY2020Q4 us-gaap Finance Lease Weighted Average Remaining Lease Term1
FinanceLeaseWeightedAverageRemainingLeaseTerm1
P2Y
CY2021Q4 us-gaap Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
0.0632
CY2020Q4 us-gaap Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
0.0649
CY2021Q4 us-gaap Finance Lease Weighted Average Discount Rate Percent
FinanceLeaseWeightedAverageDiscountRatePercent
0.0530
CY2020Q4 us-gaap Finance Lease Weighted Average Discount Rate Percent
FinanceLeaseWeightedAverageDiscountRatePercent
0.0617
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due Next Twelve Months
LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
426539
CY2021Q4 us-gaap Finance Lease Liability Payments Due Next Twelve Months
FinanceLeaseLiabilityPaymentsDueNextTwelveMonths
281042
CY2021Q4 htbx Lease Liability To Be Paid Year One
LeaseLiabilityToBePaidYearOne
707581
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Two
LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
292921
CY2021Q4 us-gaap Finance Lease Liability Payments Due Year Two
FinanceLeaseLiabilityPaymentsDueYearTwo
135632
CY2021Q4 htbx Lease Liability To Be Paid Year Two
LeaseLiabilityToBePaidYearTwo
428553
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Three
LesseeOperatingLeaseLiabilityPaymentsDueYearThree
231503
CY2021Q4 us-gaap Finance Lease Liability Payments Due Year Three
FinanceLeaseLiabilityPaymentsDueYearThree
131256
CY2021Q4 htbx Lease Liability To Be Paid Year Three
LeaseLiabilityToBePaidYearThree
362759
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Four
LesseeOperatingLeaseLiabilityPaymentsDueYearFour
238452
CY2021Q4 htbx Lease Liability To Be Paid Year Four
LeaseLiabilityToBePaidYearFour
238452
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Five
LesseeOperatingLeaseLiabilityPaymentsDueYearFive
245607
CY2021Q4 htbx Lease Liability To Be Paid Year Five
LeaseLiabilityToBePaidYearFive
245607
CY2021Q4 htbx Lessee Operating Lease Liability To Be Paid Year Six
LesseeOperatingLeaseLiabilityToBePaidYearSix
209214
CY2021Q4 htbx Lease Liability To Be Paid Year Six
LeaseLiabilityToBePaidYearSix
209214
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
1644236
CY2021Q4 us-gaap Finance Lease Liability Payments Due
FinanceLeaseLiabilityPaymentsDue
547930
CY2021Q4 htbx Lease Liability Payment Due
LeaseLiabilityPaymentDue
2192166
CY2021Q4 us-gaap Lessee Operating Lease Liability Undiscounted Excess Amount
LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
233037
CY2021Q4 us-gaap Finance Lease Liability Undiscounted Excess Amount
FinanceLeaseLiabilityUndiscountedExcessAmount
31927
CY2021Q4 htbx Lease Liability Undiscounted Excess Amount
LeaseLiabilityUndiscountedExcessAmount
264964
CY2021Q4 us-gaap Operating Lease Liability
OperatingLeaseLiability
1411199
CY2021Q4 us-gaap Finance Lease Liability
FinanceLeaseLiability
516003
CY2021Q4 htbx Lease Liability
LeaseLiability
1927202
CY2020Q4 us-gaap Lessee Operating Lease Liability Payments Due Next Twelve Months
LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
369995
CY2020Q4 us-gaap Finance Lease Liability Payments Due Next Twelve Months
FinanceLeaseLiabilityPaymentsDueNextTwelveMonths
120684
CY2020Q4 htbx Lease Liability To Be Paid Year One
LeaseLiabilityToBePaidYearOne
490679
CY2020Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Two
LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
360839
CY2020Q4 us-gaap Finance Lease Liability Payments Due Year Two
FinanceLeaseLiabilityPaymentsDueYearTwo
155694
CY2020Q4 htbx Lease Liability To Be Paid Year Two
LeaseLiabilityToBePaidYearTwo
516533
CY2020Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Three
LesseeOperatingLeaseLiabilityPaymentsDueYearThree
244973
CY2020Q4 us-gaap Finance Lease Liability Payments Due Year Three
FinanceLeaseLiabilityPaymentsDueYearThree
10284
CY2020Q4 htbx Lease Liability To Be Paid Year Three
LeaseLiabilityToBePaidYearThree
255257
CY2020Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Four
LesseeOperatingLeaseLiabilityPaymentsDueYearFour
231503
CY2020Q4 htbx Lease Liability To Be Paid Year Four
LeaseLiabilityToBePaidYearFour
231503
CY2020Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Five
LesseeOperatingLeaseLiabilityPaymentsDueYearFive
238452
CY2020Q4 htbx Lease Liability To Be Paid Year Five
LeaseLiabilityToBePaidYearFive
238452
CY2020Q4 us-gaap Lessee Operating Lease Liability Payments Due After Year Five
LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive
454820
CY2020Q4 htbx Lease Liability To Be Paid After Year Five
LeaseLiabilityToBePaidAfterYearFive
454820
CY2020Q4 us-gaap Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
1900582
CY2020Q4 us-gaap Finance Lease Liability Payments Due
FinanceLeaseLiabilityPaymentsDue
286662
CY2020Q4 htbx Lease Liability Payment Due
LeaseLiabilityPaymentDue
2187244
CY2020Q4 us-gaap Lessee Operating Lease Liability Undiscounted Excess Amount
LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
320193
CY2020Q4 us-gaap Finance Lease Liability Undiscounted Excess Amount
FinanceLeaseLiabilityUndiscountedExcessAmount
18295
CY2020Q4 htbx Lease Liability Undiscounted Excess Amount
LeaseLiabilityUndiscountedExcessAmount
338488
CY2020Q4 us-gaap Operating Lease Liability
OperatingLeaseLiability
1580389
CY2020Q4 us-gaap Finance Lease Liability
FinanceLeaseLiability
268367
CY2020Q4 htbx Lease Liability
LeaseLiability
1848756
CY2021 us-gaap Profit Loss
ProfitLoss
-35400807
CY2020 us-gaap Profit Loss
ProfitLoss
-26381389
CY2021 us-gaap Net Income Loss Attributable To Noncontrolling Interest
NetIncomeLossAttributableToNoncontrollingInterest
-329339
CY2020 us-gaap Net Income Loss Attributable To Noncontrolling Interest
NetIncomeLossAttributableToNoncontrollingInterest
-331652
CY2021 us-gaap Net Income Loss
NetIncomeLoss
-35071468
CY2020 us-gaap Net Income Loss
NetIncomeLoss
-26049737
CY2021 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
24913942
CY2020 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
15982568
CY2021 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-1.41
CY2020 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-1.63

Files In Submission

Name View Source Status
0001558370-22-003452-index-headers.html Edgar Link pending
0001558370-22-003452-index.html Edgar Link pending
0001558370-22-003452.txt Edgar Link pending
0001558370-22-003452-xbrl.zip Edgar Link pending
FilingSummary.xml Edgar Link unprocessable
Financial_Report.xlsx Edgar Link pending
htbx-20211231.xsd Edgar Link pending
htbx-20211231x10k.htm Edgar Link pending
htbx-20211231x10k_htm.xml Edgar Link completed
htbx-20211231xex10d22.htm Edgar Link pending
htbx-20211231xex10d23.htm Edgar Link pending
htbx-20211231xex10d24.htm Edgar Link pending
htbx-20211231xex10d25.htm Edgar Link pending
htbx-20211231xex10d26.htm Edgar Link pending
htbx-20211231xex10d27.htm Edgar Link pending
htbx-20211231xex10d27001.jpg Edgar Link pending
htbx-20211231xex10d27002.jpg Edgar Link pending
htbx-20211231xex10d27004.jpg Edgar Link pending
htbx-20211231xex10d28.htm Edgar Link pending
htbx-20211231xex21d1.htm Edgar Link pending
htbx-20211231xex23d1.htm Edgar Link pending
htbx-20211231xex31d1.htm Edgar Link pending
htbx-20211231xex31d2.htm Edgar Link pending
htbx-20211231xex32d1.htm Edgar Link pending
htbx-20211231xex32d2.htm Edgar Link pending
htbx-20211231xex4d19.htm Edgar Link pending
htbx-20211231_cal.xml Edgar Link unprocessable
htbx-20211231_def.xml Edgar Link unprocessable
htbx-20211231_lab.xml Edgar Link unprocessable
htbx-20211231_pre.xml Edgar Link unprocessable
MetaLinks.json Edgar Link pending
R1.htm Edgar Link pending
R10.htm Edgar Link pending
R11.htm Edgar Link pending
R12.htm Edgar Link pending
R13.htm Edgar Link pending
R14.htm Edgar Link pending
R15.htm Edgar Link pending
R16.htm Edgar Link pending
R17.htm Edgar Link pending
R18.htm Edgar Link pending
R19.htm Edgar Link pending
R2.htm Edgar Link pending
R20.htm Edgar Link pending
R21.htm Edgar Link pending
R22.htm Edgar Link pending
R23.htm Edgar Link pending
R24.htm Edgar Link pending
R25.htm Edgar Link pending
R26.htm Edgar Link pending
R27.htm Edgar Link pending
R28.htm Edgar Link pending
R29.htm Edgar Link pending
R3.htm Edgar Link pending
R30.htm Edgar Link pending
R31.htm Edgar Link pending
R32.htm Edgar Link pending
R33.htm Edgar Link pending
R34.htm Edgar Link pending
R35.htm Edgar Link pending
R36.htm Edgar Link pending
R37.htm Edgar Link pending
R38.htm Edgar Link pending
R39.htm Edgar Link pending
R4.htm Edgar Link pending
R40.htm Edgar Link pending
R41.htm Edgar Link pending
R42.htm Edgar Link pending
R43.htm Edgar Link pending
R44.htm Edgar Link pending
R45.htm Edgar Link pending
R46.htm Edgar Link pending
R47.htm Edgar Link pending
R48.htm Edgar Link pending
R49.htm Edgar Link pending
R5.htm Edgar Link pending
R50.htm Edgar Link pending
R51.htm Edgar Link pending
R52.htm Edgar Link pending
R53.htm Edgar Link pending
R54.htm Edgar Link pending
R55.htm Edgar Link pending
R56.htm Edgar Link pending
R57.htm Edgar Link pending
R58.htm Edgar Link pending
R59.htm Edgar Link pending
R6.htm Edgar Link pending
R60.htm Edgar Link pending
R61.htm Edgar Link pending
R62.htm Edgar Link pending
R63.htm Edgar Link pending
R64.htm Edgar Link pending
R65.htm Edgar Link pending
R66.htm Edgar Link pending
R67.htm Edgar Link pending
R68.htm Edgar Link pending
R69.htm Edgar Link pending
R7.htm Edgar Link pending
R70.htm Edgar Link pending
R8.htm Edgar Link pending
R9.htm Edgar Link pending
report.css Edgar Link pending
Show.js Edgar Link pending