Financial Snapshot

Revenue
$173.7M
TTM
Gross Margin
75.49%
TTM
Net Earnings
$85.71M
TTM
Current Assets
Q3 2024
Current Liabilities
Q3 2024
Current Ratio
810.16%
Q3 2024
Total Assets
Q3 2024
Total Liabilities
Q3 2024
Book Value
$169.4M
Q3 2024
Cash
Q3 2024
P/E
5.507
Nov 13, 2024 EST
Free Cash Flow
$78.86M
TTM

Revenues

Revenues

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Revenue YoY Change

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Revenues

Concept 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996
Revenue $139.9M $110.8M $133.7M $125.0M $26.74M $477.1M $12.27M $14.99M $8.200M $3.100M $5.500M $9.000M $12.70M $19.20M $13.80M $8.100M $6.700M $7.300M $8.500M $1.800M $700.0K $300.0K $1.200M $500.0K $500.0K $500.0K $700.0K $0.00
YoY Change 26.31% -17.13% 6.97% 367.28% -94.39% 3788.3% -18.14% 82.78% 164.52% -43.64% -38.89% -29.13% -33.85% 39.13% 70.37% 20.9% -8.22% -14.12% 372.22% 157.14% 133.33% -75.0% 140.0% 0.0% 0.0% -28.57%

Expenses

Cost Of Revenues

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Gross Profit

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Gross Profit Margin

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Gross Profit

Concept 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996
Revenue $139.9M $110.8M $133.7M $125.0M $26.74M $477.1M $12.27M $14.99M $8.200M $3.100M $5.500M $9.000M $12.70M $19.20M $13.80M $8.100M $6.700M $7.300M $8.500M $1.800M $700.0K $300.0K $1.200M $500.0K $500.0K $500.0K $700.0K $0.00
Cost Of Revenue $17.23M $10.43M $16.60M $14.80M $1.783M $95.27M $0.00 $0.00
Gross Profit $122.7M $100.3M $117.1M $110.2M $24.96M $381.8M $12.27M $14.99M
Gross Profit Margin 87.69% 90.58% 87.58% 88.16% 93.33% 80.03% 100.0% 100.0%

Selling, General & Admin Expense

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Research & Development

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Depreciation, Depletion & Amortization

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SGA Expense to Gross Profit Ratio

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R&D To Gross Profit Ratio

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DDA To Gross Profit Ratio

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Operating Expenses Total

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Operating Profits/Loss

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Operational Expenses

Concept 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996
Selling, General & Admin $22.04M $35.12M $17.32M $14.00M $13.25M $12.88M $12.30M $13.71M $10.58M $12.65M $13.12M $10.97M $23.93M $8.131M $7.533M $4.600M $3.700M $4.600M $2.500M $4.000M $2.600M $1.800M $2.600M $4.900M $2.300M $2.800M $1.600M $1.200M
YoY Change -37.23% 102.72% 23.71% 5.67% 2.89% 4.69% -10.29% 29.59% -16.33% -3.6% 19.62% -54.17% 194.34% 7.93% 63.76% 24.32% -19.57% 84.0% -37.5% 53.85% 44.44% -30.77% -46.94% 113.04% -17.86% 75.0% 33.33%
% of Gross Profit 17.97% 35.0% 14.8% 12.71% 53.1% 3.37% 100.28% 91.5%
Research & Development $16.43M $22.53M $9.942M $10.94M $13.30M $13.02M $16.68M $19.71M $13.13M $10.71M $13.79M $18.21M $18.37M $22.66M $17.42M $11.60M $9.900M $9.100M $8.300M $4.200M $2.900M $1.800M $1.700M $2.600M $1.700M $4.400M $900.0K $700.0K
YoY Change -27.07% 126.57% -9.11% -17.77% 2.2% -21.96% -15.38% 50.11% 22.63% -22.33% -24.31% -0.84% -18.94% 30.05% 50.2% 17.17% 8.79% 9.64% 97.62% 44.83% 61.11% 5.88% -34.62% 52.94% -61.36% 388.89% 28.57%
% of Gross Profit 13.39% 22.45% 8.49% 9.93% 53.3% 3.41% 135.95% 131.51%
Depreciation & Amortization $538.3K $500.0K $500.0K $529.8K $527.0K $69.63K $132.2K $174.3K $247.4K $351.6K $463.1K $419.4K $568.3K $625.3K $475.1K $460.0K $1.250M $1.560M $1.330M $1.050M $750.0K $320.0K $320.0K $360.0K $370.0K $210.0K $10.00K $10.00K
YoY Change 7.66% 0.0% -5.63% 0.53% 656.85% -47.33% -24.15% -29.55% -29.64% -24.09% 10.44% -26.21% -9.12% 31.63% 3.28% -63.2% -19.87% 17.29% 26.67% 40.0% 134.38% 0.0% -11.11% -2.7% 76.19% 2000.0% 0.0%
% of Gross Profit 0.44% 0.5% 0.43% 0.48% 2.11% 0.02% 1.08% 1.16%
Operating Expenses $38.47M $57.64M $27.27M $24.94M $29.06M $122.0M $31.12M $46.00M $39.13M $212.8M $29.04M $31.51M $44.11M $31.94M $25.69M $16.80M $14.20M $14.10M $11.00M $8.600M $5.900M $3.700M $4.400M $7.500M $4.200M $7.400M $2.900M $2.300M
YoY Change -33.26% 111.41% 9.32% -14.18% -76.17% 291.91% -32.36% 17.57% -81.61% 632.92% -7.84% -28.57% 38.1% 24.32% 52.92% 18.31% 0.71% 28.18% 27.91% 45.76% 59.46% -15.91% -41.33% 78.57% -43.24% 155.17% 26.09%
Operating Profit $84.22M $42.70M $89.09M $84.50M -$2.322M $355.1M -$18.85M -$31.01M -$30.95M -$209.7M -$23.52M -$22.54M -$31.38M -$12.72M -$11.88M
YoY Change 97.24% -52.07% 5.43% -3738.91% -100.65% -1983.9% -39.23% 0.2% -85.24% 791.59% 4.35% -28.19% 146.66% 7.1%

Interest Expenses

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Interest Expenses To Operating Income %

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Other Expense/Income

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Interest & Other Expense/Income

Concept 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996
Interest Expense $0.00 $0.00 $0.00 $3.017M $15.77M $15.48M $14.76M $2.396M $266.7K $455.8K $1.207M $173.0K $0.00 $0.00 -$7.500M -$1.500M $1.400M -$3.100M $200.0K $0.00 $0.00 $100.0K $400.0K $0.00 $0.00
YoY Change -100.0% -80.87% 1.88% 4.88% 516.07% 798.12% -41.48% -62.25% 597.91% -100.0% 400.0% -207.14% -145.16% -1650.0% -75.0%
% of Operating Profit 0.0% 0.0% 0.0% 3.57% 4.36%
Other Income/Expense, Net $4.156M $1.032M $101.2K $532.1K $2.822M $78.94M $16.79K $102.3K $42.20K $1.065K $1.497K $522.00 $13.06K $659.3K $1.437K $100.0K $400.0K $0.00 $0.00 $100.0K $0.00 $0.00 -$200.0K -$600.0K $0.00
YoY Change 302.7% 919.95% -80.99% -81.15% -96.42% 470122.69% -83.59% 142.46% 3862.63% -28.86% 186.78% -96.0% -98.02% 45779.75% -98.56% -75.0% -100.0% -100.0% -66.67%

Income/Loss

Pretax Income

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Income Tax

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Net Profits/Loss

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Pretax Income YoY Change

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Income Tax Rate

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Net Profits/Loss YoY Change

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Basic EPS

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Net Income To Revenue Ratio

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Pretax & Net Income

Concept 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996
Pretax Income $87.78M $44.13M $89.31M $73.51M -$10.18M $411.6M -$38.33M -$39.68M -$38.99M -$211.9M -$24.80M -$21.90M -$6.932M -$28.02M -$19.40M -$10.20M -$5.600M -$9.900M -$2.300M -$9.400M -$5.300M -$3.300M -$3.700M -$7.800M -$3.600M -$6.600M -$2.200M -$2.300M
YoY Change 98.89% -50.59% 21.5% -822.2% -102.47% -1173.96% -3.41% 1.78% -81.6% 754.72% 13.2% 215.98% -75.26% 44.43% 90.2% 82.14% -43.43% 330.43% -75.53% 77.36% 60.61% -10.81% -52.56% 116.67% -45.45% 200.0% -4.35%
Income Tax $19.71M $10.23M $19.86M $17.17M -$2.937M -$10.17M -$2.094M $13.88K $462.0K $53.53M -$7.618M -$7.844M -$36.03M $175.2K $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00
% Of Pretax Income 22.45% 23.18% 22.24% 23.35% -2.47%
Net Earnings $68.07M $33.90M $69.45M $56.34M -$7.241M $421.8M -$36.24M -$39.70M -$39.45M -$265.5M -$17.18M -$14.06M $29.10M -$28.20M -$19.40M -$10.20M -$5.600M -$9.900M -$2.300M -$9.400M -$5.300M -$3.300M -$3.700M -$7.800M -$3.600M -$6.600M -$2.200M -$2.300M
YoY Change 100.76% -51.18% 23.27% -878.08% -101.72% -1264.07% -8.72% 0.63% -85.14% 1445.43% 22.18% -148.32% -203.21% 45.33% 90.2% 82.14% -43.43% 330.43% -75.53% 77.36% 60.61% -10.81% -52.56% 116.67% -45.45% 200.0% -4.35%
Net Earnings / Revenue 48.65% 30.61% 51.96% 45.09% -27.08% 88.42% -295.34% -264.87% -481.11% -8563.33% -312.32% -156.22% 229.13% -146.85% -140.58% -125.93% -83.58% -135.62% -27.06% -522.22% -757.14% -1100.0% -308.33% -1560.0% -720.0% -1320.0% -314.29%
Basic Earnings Per Share $0.95 $0.46 $0.92 $0.71 -$0.09 $5.28 -$0.46 -$0.69 -$0.73 -$4.97 -$0.33 -$0.27 $0.57 -$0.62 -$0.52
Diluted Earnings Per Share $0.95 $0.46 $0.91 $0.71 -$0.15 $5.18 -$0.46 -$0.69 -$0.73 -$4.97 -$0.33 -$0.27 $0.09 -$0.62 -$0.52 -$293.9K -$168.2K -$351.1K -$92.74K -$396.6K -$337.6K -$314.3K -$435.3K -$1.083M -$545.5K -$1.015M -$523.8K -$766.7K

Assets & Liabilities

Cash & Short-Term Investments

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Cash & Equivalents

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Cash To Operating Expenses Ratio

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Inventory

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Receivables

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Total Short-Term Assets

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Property, Plant And Equipment

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Long-Term Investments

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Total Long-Term Assets

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Total Assets

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Net Income To Total Assets Percentage

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Accounts Payable

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Short-Term Debt

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Long Term Debt Due

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Total Short-Term Liabilities

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Long-Term Debt

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Other Long-Term Liabilities

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Total Long-Term Liabilities

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Total Liabilities

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Short-Term To Long-Term Debt Ratio

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Short-Term Assets To Debt Ratio

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Long-Term Debt To Net Income Ratio

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Assets & Liabilities

Concept 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996
Cash & Short-Term Investments $150.1M $98.79M $103.1M $117.9M $65.20M $100.7M $19.90M $28.70M $112.7M $99.70M $91.30M $32.00M $49.30M $21.30M $19.50M $2.300M $6.800M $10.60M $1.800M $2.000M $1.400M $2.100M $3.100M $1.700M $1.800M $5.000M $10.70M $0.00
YoY Change 51.98% -4.22% -12.52% 80.83% -35.25% 406.03% -30.66% -74.53% 13.04% 9.2% 185.31% -35.09% 131.46% 9.23% 747.83% -66.18% -35.85% 488.89% -10.0% 42.86% -33.33% -32.26% 82.35% -5.56% -64.0% -53.27%
Cash & Equivalents $150.1M $98.79M $103.1M $117.9M $65.20M $100.7M $19.90M $28.70M $112.7M $99.70M $91.30M $32.00M $49.30M $6.300M $14.50M $2.300M $6.800M $10.60M $1.800M $2.000M $1.400M $2.100M $3.100M $1.700M $1.800M $5.000M $10.70M $0.00
Short-Term Investments $15.00M $5.000M $0.00
Other Short-Term Assets $3.496M $2.316M $2.453M $2.100M $100.9M $15.80M $12.70M $11.10M $600.0K $10.60M $11.20M $34.30M $1.100M $400.0K $1.600M $2.000M $100.0K $100.0K $200.0K $300.0K $100.0K $100.0K $200.0K $0.00 $0.00 $100.0K $100.0K $500.0K
YoY Change 50.97% -5.62% 16.83% -97.92% 538.61% 24.41% 14.41% 1750.0% -94.34% -5.36% -67.35% 3018.18% 175.0% -75.0% -20.0% 1900.0% 0.0% -50.0% -33.33% 200.0% 0.0% -50.0% -100.0% 0.0% -80.0%
Inventory $64.22M $39.27M $19.51M $20.30M $9.700M $2.900M $3.000M $26.20M $12.40M $19.00M $20.50M $17.60M $0.00
Prepaid Expenses
Receivables $21.13M $45.41M $83.65M $3.300M $4.200M $2.000M $1.800M $3.200M $3.700M $500.0K $1.000M $1.000M $2.600M $3.000M $2.400M $2.000M $1.000M $600.0K $900.0K $100.0K $0.00 $100.0K $100.0K $0.00 $0.00 $0.00 $200.0K $0.00
Other Receivables $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00
Total Short-Term Assets $239.0M $185.8M $208.8M $143.6M $180.0M $121.3M $37.40M $69.20M $129.5M $129.8M $123.9M $84.90M $53.00M $24.70M $23.50M $6.300M $7.900M $11.40M $2.800M $2.400M $1.500M $2.200M $3.400M $1.800M $1.800M $5.100M $10.90M $500.0K
YoY Change 28.64% -11.0% 45.37% -20.22% 48.39% 224.33% -45.95% -46.56% -0.23% 4.76% 45.94% 60.19% 114.57% 5.11% 273.02% -20.25% -30.7% 307.14% 16.67% 60.0% -31.82% -35.29% 88.89% 0.0% -64.71% -53.21% 2080.0%
Property, Plant & Equipment $1.332M $1.848M $2.366M $2.100M $2.600M $200.0K $100.0K $300.0K $400.0K $800.0K $1.400M $1.000M $800.0K $1.200M $1.200M $1.400M $1.500M $1.300M $1.200M $500.0K $400.0K $400.0K $700.0K $1.000M $1.400M $1.700M $0.00 $0.00
YoY Change -27.95% -21.88% 12.66% -19.23% 1200.0% 100.0% -66.67% -25.0% -50.0% -42.86% 40.0% 25.0% -33.33% 0.0% -14.29% -6.67% 15.38% 8.33% 140.0% 25.0% 0.0% -42.86% -30.0% -28.57% -17.65%
Goodwill
YoY Change
Intangibles
YoY Change
Long-Term Investments $0.00 $300.0K $0.00 $100.0K $0.00
YoY Change -100.0% -100.0%
Other Assets $13.13M $6.503M $2.709M $3.200M $15.00M $81.10M $106.3M $90.60M $54.90M $34.90M $67.60M $15.20M $35.70M $300.0K $300.0K $300.0K $300.0K $200.0K $200.0K $200.0K $200.0K $200.0K $100.0K $200.0K $100.0K $100.0K $100.0K $0.00
YoY Change 101.93% 140.03% -15.34% -78.67% -81.5% -23.71% 17.33% 65.03% 57.31% -48.37% 344.74% -57.42% 11800.0% 0.0% 0.0% 0.0% 50.0% 0.0% 0.0% 0.0% 0.0% 100.0% -50.0% 100.0% 0.0% 0.0%
Total Long-Term Assets $15.36M $9.250M $5.973M $6.200M $18.60M $82.10M $107.3M $91.80M $56.20M $36.60M $69.90M $20.90M $37.40M $2.300M $2.400M $2.500M $2.700M $2.600M $3.300M $3.700M $4.600M $600.0K $800.0K $1.400M $1.600M $2.000M $200.0K $100.0K
YoY Change 66.08% 54.84% -3.65% -66.67% -77.34% -23.49% 16.88% 63.35% 53.55% -47.64% 234.45% -44.12% 1526.09% -4.17% -4.0% -7.41% 3.85% -21.21% -10.81% -19.57% 666.67% -25.0% -42.86% -12.5% -20.0% 900.0% 100.0%
Total Assets $254.4M $195.0M $214.7M $149.8M $198.6M $203.4M $144.7M $161.0M $185.7M $166.4M $193.8M $105.8M $90.40M $27.00M $25.90M $8.800M $10.60M $14.00M $6.100M $6.100M $6.100M $2.800M $4.200M $3.200M $3.400M $7.100M $11.10M $600.0K
YoY Change
Accounts Payable $1.456M $3.355M $2.028M $1.300M $3.100M $1.700M $1.300M $2.500M $3.900M $3.400M $5.100M $10.20M $2.300M $2.900M $3.500M $1.800M $1.300M $1.400M $1.300M $1.100M $400.0K $500.0K $200.0K $200.0K $200.0K $300.0K $200.0K $100.0K
YoY Change -56.6% 65.45% 56.0% -58.06% 82.35% 30.77% -48.0% -35.9% 14.71% -33.33% -50.0% 343.48% -20.69% -17.14% 94.44% 38.46% -7.14% 7.69% 18.18% 175.0% -20.0% 150.0% 0.0% 0.0% -33.33% 50.0% 100.0%
Accrued Expenses $7.522M $4.995M $4.930M $4.500M $6.300M $5.500M $4.200M $4.600M $3.400M $2.100M $4.800M $4.300M $4.600M $1.400M $700.0K $1.200M $800.0K $600.0K $500.0K $400.0K $200.0K $200.0K $300.0K $300.0K $100.0K $100.0K $200.0K $0.00
YoY Change 50.59% 1.33% 9.55% -28.57% 14.55% 30.95% -8.7% 35.29% 61.9% -56.25% 11.63% -6.52% 228.57% 100.0% -41.67% 50.0% 33.33% 20.0% 25.0% 100.0% 0.0% -33.33% 0.0% 200.0% 0.0% -50.0%
Deferred Revenue
YoY Change
Short-Term Debt $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00
YoY Change
Long-Term Debt Due $0.00 $80.00M $0.00 $2.000M $2.000M $1.000M $0.00 $0.00 $100.0K $100.0K $0.00 $0.00 $0.00 $200.0K $400.0K $300.0K $400.0K $0.00
YoY Change -100.0% -100.0% 0.0% 100.0% -100.0% 0.0% -100.0% -50.0% 33.33% -25.0%
Total Short-Term Liabilities $54.12M $21.52M $30.49M $10.50M $91.70M $11.30M $6.800M $7.100M $7.300M $7.500M $12.20M $15.80M $7.000M $4.300M $9.000M $4.300M $2.100M $2.100M $2.200M $1.600M $500.0K $700.0K $700.0K $1.400M $600.0K $800.0K $500.0K $200.0K
YoY Change 151.5% -29.42% 190.36% -88.55% 711.5% 66.18% -4.23% -2.74% -2.67% -38.52% -22.78% 125.71% 62.79% -52.22% 109.3% 104.76% 0.0% -4.55% 37.5% 220.0% -28.57% 0.0% -50.0% 133.33% -25.0% 60.0% 150.0%
Long-Term Debt $0.00 $0.00 $0.00 $0.00 $0.00 $75.50M $71.10M $66.60M $0.00 $0.00 $2.000M $4.000M $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $100.0K $0.00 $0.00 $0.00 $0.00 $800.0K $500.0K $700.0K $0.00 $0.00
YoY Change -100.0% 6.19% 6.76% -100.0% -50.0% -100.0% -100.0% 60.0% -28.57%
Other Long-Term Liabilities $3.376M $3.358M $9.924M $9.600M $9.000M $13.60M $389.9M $374.5M $462.6M $399.5M $162.7M $57.90M $42.60M $10.50M $9.700M $4.500M $3.200M $4.700M $500.0K $0.00 $0.00 $100.0K $0.00
YoY Change 0.54% -66.16% 3.38% 6.67% -33.82% -96.51% 4.11% -19.04% 15.79% 145.54% 181.0% 35.92% 305.71% 8.25% 115.56% 40.63% -31.91% 840.0% -100.0%
Total Long-Term Liabilities $3.376M $3.358M $9.924M $9.600M $9.000M $89.10M $461.0M $441.1M $462.6M $399.5M $164.7M $61.90M $42.60M $10.50M $9.700M $4.500M $3.200M $4.700M $600.0K $0.00 $0.00 $0.00 $0.00 $900.0K $500.0K $700.0K $0.00 $0.00
YoY Change 0.54% -66.16% 3.38% 6.67% -89.9% -80.67% 4.51% -4.65% 15.79% 142.56% 166.07% 45.31% 305.71% 8.25% 115.56% 40.63% -31.91% 683.33% -100.0% 80.0% -28.57%
Total Liabilities $57.49M $24.88M $40.41M $20.00M $100.8M $100.5M $467.8M $448.4M $470.2M $412.9M $176.8M $77.60M $49.60M $15.00M $18.80M $8.800M $5.400M $6.700M $2.900M $1.600M $500.0K $700.0K $700.0K $2.300M $1.200M $1.400M $500.0K $200.0K
YoY Change 131.12% -38.44% 102.06% -80.16% 0.3% -78.52% 4.33% -4.64% 13.88% 133.54% 127.84% 56.45% 230.67% -20.21% 113.64% 62.96% -19.4% 131.03% 81.25% 220.0% -28.57% 0.0% -69.57% 91.67% -14.29% 180.0% 150.0%

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Market Cap: $471.98 Million

About SIGA Technologies Inc

SIGA Technologies, Inc. is a commercial-stage pharmaceutical company, which engages in the development and commercialization of solutions for serious unmet medical needs and biothreats. The company is headquartered in New York City, New York and currently employs 45 full-time employees. Health security comprises countermeasures for biological, chemical, radiological and nuclear attacks, vaccines and therapies for emerging infectious diseases, and health preparedness. The firm's lead product is TPOXX, also known as tecovirimat and ST-246, an orally administered and intravenous (IV) formulation antiviral drug for the treatment of human smallpox disease caused by variola virus. TPOXX is a novel small-molecule drug and the United States maintains a supply of TPOXX under Project BioShield. The European Medicines Agency and United Kingdom approvals include labeling for oral tecovirimat indicating its use for the treatment of smallpox, monkeypox, cowpox, and vaccinia complications following vaccination against smallpox. The company uses third parties known as contract manufacturing organizations to procure commercial raw materials and supplies, and to manufacture TPOXX.

Industry: Pharmaceutical Preparations Peers: Aclaris Therapeutics Inc Innoviva Inc AERIE PHARMACEUTICALS INC Amneal Pharmaceuticals Inc Belite Bio Inc BIODELIVERY SCIENCES INTERNATIONAL INC DICE Therapeutics, Inc. Johnson & Johnson REATA PHARMACEUTICALS INC