2018 Q1 Form 10-K Financial Statement
#000156459018004911 Filed on March 08, 2018
Income Statement
Concept | 2018 Q1 | 2017 Q4 | 2017 |
---|---|---|---|
Revenue | $379.0K | $1.193M | $2.108M |
YoY Change | 24.26% | 291.15% | 72.79% |
Cost Of Revenue | |||
YoY Change | |||
Gross Profit | |||
YoY Change | |||
Gross Profit Margin | |||
Selling, General & Admin | $4.790M | $4.080M | $15.86M |
YoY Change | 21.88% | 37.37% | 19.07% |
% of Gross Profit | |||
Research & Development | $15.34M | $16.60M | $48.20M |
YoY Change | 60.58% | 95.88% | 52.22% |
% of Gross Profit | |||
Depreciation & Amortization | $150.0K | $76.00K | |
YoY Change | 66.67% | -14.61% | |
% of Gross Profit | |||
Operating Expenses | $20.13M | $20.68M | $64.06M |
YoY Change | 49.31% | 80.69% | 42.4% |
Operating Profit | -$19.75M | -$19.49M | -$61.95M |
YoY Change | 49.89% | 74.93% | 41.56% |
Interest Expense | $475.0K | $460.0K | $1.421M |
YoY Change | 83.4% | 70.37% | 48.64% |
% of Operating Profit | |||
Other Income/Expense, Net | $353.0K | $385.0K | $1.152M |
YoY Change | 71.36% | 18.1% | -263.17% |
Pretax Income | -$19.40M | -$19.10M | -$60.80M |
YoY Change | 49.58% | 76.52% | 36.72% |
Income Tax | $0.00 | $0.00 | $0.00 |
% Of Pretax Income | |||
Net Earnings | -$19.40M | -$19.10M | -$60.80M |
YoY Change | 49.55% | 76.64% | 36.72% |
Net Earnings / Revenue | -5118.21% | -1601.34% | -2884.35% |
Basic Earnings Per Share | |||
Diluted Earnings Per Share | -$792.5K | -$796.5K | -$2.895M |
COMMON SHARES | |||
Basic Shares Outstanding | 24.70M | 24.39M shares | |
Diluted Shares Outstanding |
Balance Sheet
Concept | 2018 Q1 | 2017 Q4 | 2017 |
---|---|---|---|
SHORT-TERM ASSETS | |||
Cash & Short-Term Investments | $114.0M | $131.3M | $131.3M |
YoY Change | 19.75% | 22.71% | 22.71% |
Cash & Equivalents | $28.20M | $35.17M | $35.20M |
Short-Term Investments | $86.00M | $96.10M | $96.10M |
Other Short-Term Assets | $5.000M | $1.800M | $1.800M |
YoY Change | 212.5% | 50.0% | 50.0% |
Inventory | |||
Prepaid Expenses | |||
Receivables | |||
Other Receivables | |||
Total Short-Term Assets | $119.3M | $133.4M | $133.4M |
YoY Change | 22.92% | 22.98% | 22.95% |
LONG-TERM ASSETS | |||
Property, Plant & Equipment | $400.0K | $267.0K | $300.0K |
YoY Change | 70.94% | 2.69% | 0.0% |
Goodwill | |||
YoY Change | |||
Intangibles | |||
YoY Change | |||
Long-Term Investments | $3.200M | $3.200M | |
YoY Change | |||
Other Assets | $200.0K | $231.0K | $200.0K |
YoY Change | -46.81% | -4.94% | 0.0% |
Total Long-Term Assets | $700.0K | $3.744M | $3.800M |
YoY Change | 14.75% | 644.33% | 660.0% |
TOTAL ASSETS | |||
Total Short-Term Assets | $119.3M | $133.4M | $133.4M |
Total Long-Term Assets | $700.0K | $3.744M | $3.800M |
Total Assets | $120.0M | $137.2M | $137.2M |
YoY Change | 22.87% | 25.84% | 25.87% |
SHORT-TERM LIABILITIES | |||
YoY Change | |||
Accounts Payable | $2.600M | $2.232M | $2.200M |
YoY Change | -5.14% | -6.02% | -8.33% |
Accrued Expenses | $12.80M | $12.00M | $12.00M |
YoY Change | 82.86% | 76.47% | 76.47% |
Deferred Revenue | $1.573M | ||
YoY Change | |||
Short-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Long-Term Debt Due | |||
YoY Change | |||
Total Short-Term Liabilities | $16.90M | $15.80M | $15.80M |
YoY Change | 53.79% | 52.4% | 51.92% |
LONG-TERM LIABILITIES | |||
Long-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Other Long-Term Liabilities | $16.10M | $310.0K | $17.10M |
YoY Change | 10778.38% | 7.64% | 17.93% |
Total Long-Term Liabilities | $16.10M | $17.07M | $17.10M |
YoY Change | 14.48% | 17.65% | 17.93% |
TOTAL LIABILITIES | |||
Total Short-Term Liabilities | $16.90M | $15.80M | $15.80M |
Total Long-Term Liabilities | $16.10M | $17.07M | $17.10M |
Total Liabilities | $33.00M | $32.87M | $32.90M |
YoY Change | 31.73% | 32.13% | 32.13% |
SHAREHOLDERS EQUITY | |||
Retained Earnings | -$366.1M | ||
YoY Change | 19.92% | ||
Common Stock | $470.6M | ||
YoY Change | 20.85% | ||
Preferred Stock | |||
YoY Change | |||
Treasury Stock (at cost) | |||
YoY Change | |||
Treasury Stock Shares | |||
Shareholders Equity | $86.95M | $104.3M | $104.3M |
YoY Change | |||
Total Liabilities & Shareholders Equity | $120.0M | $137.2M | $137.2M |
YoY Change | 22.87% | 25.84% | 25.87% |
Cashflow Statement
Concept | 2018 Q1 | 2017 Q4 | 2017 |
---|---|---|---|
OPERATING ACTIVITIES | |||
Net Income | -$19.40M | -$19.10M | -$60.80M |
YoY Change | 49.55% | 76.64% | 36.72% |
Depreciation, Depletion And Amortization | $150.0K | $76.00K | |
YoY Change | 66.67% | -14.61% | |
Cash From Operating Activities | -$19.87M | -$12.72M | -$47.37M |
YoY Change | 56.83% | 22.07% | 34.74% |
INVESTING ACTIVITIES | |||
Capital Expenditures | $173.0K | -$40.00K | $84.00K |
YoY Change | -67.82% | ||
Acquisitions | |||
YoY Change | |||
Other Investing Activities | $12.82M | $1.590M | -$16.99M |
YoY Change | 15.91% | -92.55% | -6.24% |
Cash From Investing Activities | $12.64M | $1.550M | -$17.07M |
YoY Change | 14.32% | -92.73% | -6.62% |
FINANCING ACTIVITIES | |||
Cash Dividend Paid | |||
YoY Change | |||
Common Stock Issuance & Retirement, Net | $24.90M | ||
YoY Change | |||
Debt Paid & Issued, Net | |||
YoY Change | |||
Cash From Financing Activities | 33.00K | 25.61M | 75.72M |
YoY Change | -72.5% | 14964.71% | 39.7% |
NET CHANGE | |||
Cash From Operating Activities | -19.87M | -12.72M | -47.37M |
Cash From Investing Activities | 12.64M | 1.550M | -17.07M |
Cash From Financing Activities | 33.00K | 25.61M | 75.72M |
Net Change In Cash | -7.193M | 14.44M | 11.28M |
YoY Change | 367.99% | 30.32% | 1380.18% |
FREE CASH FLOW | |||
Cash From Operating Activities | -$19.87M | -$12.72M | -$47.37M |
Capital Expenditures | $173.0K | -$40.00K | $84.00K |
Free Cash Flow | -$20.04M | -$12.68M | -$47.46M |
YoY Change | 58.19% | 21.69% | 33.99% |
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|
-60802000 | |
CY2016 | us-gaap |
Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
|
-47070000 | |
CY2015 | us-gaap |
Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
|
-103845000 | |
CY2017 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-2.90 | |
CY2016 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-3.22 | |
CY2015 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-1519.27 | |
CY2017 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
20997211 | |
CY2016 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
14619716 | |
CY2015 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
68352 | |
CY2017 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-61001000 | |
CY2015 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-24091000 | |
CY2014Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
-152569000 | |
CY2015 | sndx |
Convertible Preferred Stock Accretion To Redemption Value Adjustment
ConvertiblePreferredStockAccretionToRedemptionValueAdjustment
|
69715000 | |
CY2015 | sndx |
Convertible Preferred Stock Accretion Of Dividends
ConvertiblePreferredStockAccretionOfDividends
|
10011000 | |
CY2015 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
75000 | |
CY2015 | us-gaap |
Stock Issued During Period Value Restricted Stock Award Gross
StockIssuedDuringPeriodValueRestrictedStockAwardGross
|
14000 | |
CY2016 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
2058000 | |
CY2016 | us-gaap |
Stock Issued During Period Value Restricted Stock Award Gross
StockIssuedDuringPeriodValueRestrictedStockAwardGross
|
42000 | |
CY2016 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
4708000 | |
CY2016 | us-gaap |
Adjustments To Additional Paid In Capital Stock Split
AdjustmentsToAdditionalPaidInCapitalStockSplit
|
1000 | |
CY2017 | sndx |
Stock Issued During Period Value Follow On Offering Net Of Offering Cost
StockIssuedDuringPeriodValueFollowOnOfferingNetOfOfferingCost
|
48675000 | |
CY2017 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
277000 | |
CY2017 | us-gaap |
Stock Issued During Period Value Restricted Stock Award Gross
StockIssuedDuringPeriodValueRestrictedStockAwardGross
|
59000 | |
CY2017 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
5450000 | |
CY2017 | sndx |
Stock Issued During Period Value At The Market Offering Net
StockIssuedDuringPeriodValueAtTheMarketOfferingNet
|
1705000 | |
CY2017 | us-gaap |
Adjustment To Additional Paid In Capital Income Tax Effect From Share Based Compensation Net
AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet
|
97000 | |
CY2017 | sndx |
Stock Issued During Period Value Direct Stock Placement Net
StockIssuedDuringPeriodValueDirectStockPlacementNet
|
24918000 | |
CY2017 | sndx |
Adjustments To Additional Paid In Capital Follow On Offering Cost
AdjustmentsToAdditionalPaidInCapitalFollowOnOfferingCost
|
3665000 | |
CY2015 | us-gaap |
Amortization Of Financing Costs And Discounts
AmortizationOfFinancingCostsAndDiscounts
|
762000 | |
CY2017 | us-gaap |
Increase Decrease In Deferred Revenue
IncreaseDecreaseInDeferredRevenue
|
2892000 | |
CY2016 | us-gaap |
Increase Decrease In Deferred Revenue
IncreaseDecreaseInDeferredRevenue
|
-1220000 | |
CY2015 | us-gaap |
Increase Decrease In Deferred Revenue
IncreaseDecreaseInDeferredRevenue
|
16660000 | |
CY2017 | us-gaap |
Net Cash Provided By Used In Operating Activities Continuing Operations
NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
|
-47371000 | |
CY2016 | us-gaap |
Net Cash Provided By Used In Operating Activities Continuing Operations
NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
|
-35157000 | |
CY2015 | us-gaap |
Net Cash Provided By Used In Operating Activities Continuing Operations
NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
|
-2428000 | |
CY2015 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
49000 | |
CY2017 | us-gaap |
Increase Decrease In Restricted Cash
IncreaseDecreaseInRestrictedCash
|
-45000 | |
CY2016 | us-gaap |
Increase Decrease In Restricted Cash
IncreaseDecreaseInRestrictedCash
|
97000 | |
CY2015 | us-gaap |
Increase Decrease In Restricted Cash
IncreaseDecreaseInRestrictedCash
|
118000 | |
CY2017 | us-gaap |
Payments To Acquire Short Term Investments
PaymentsToAcquireShortTermInvestments
|
152263000 | |
CY2016 | us-gaap |
Payments To Acquire Short Term Investments
PaymentsToAcquireShortTermInvestments
|
158319000 | |
CY2015 | us-gaap |
Payments To Acquire Short Term Investments
PaymentsToAcquireShortTermInvestments
|
102008000 | |
CY2017 | us-gaap |
Proceeds From Sale And Maturity Of Available For Sale Securities
ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities
|
135275000 | |
CY2016 | us-gaap |
Proceeds From Sale And Maturity Of Available For Sale Securities
ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities
|
140297000 | |
CY2015 | us-gaap |
Proceeds From Sale And Maturity Of Available For Sale Securities
ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities
|
40506000 | |
CY2017 | us-gaap |
Net Cash Provided By Used In Investing Activities Continuing Operations
NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
|
-17027000 | |
CY2016 | us-gaap |
Net Cash Provided By Used In Investing Activities Continuing Operations
NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
|
-18380000 | |
CY2015 | us-gaap |
Net Cash Provided By Used In Investing Activities Continuing Operations
NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
|
-61669000 | |
CY2016 | us-gaap |
Proceeds From Issuance Initial Public Offering
ProceedsFromIssuanceInitialPublicOffering
|
52148000 | |
CY2015 | us-gaap |
Proceeds From Issuance Of Convertible Preferred Stock
ProceedsFromIssuanceOfConvertiblePreferredStock
|
87323000 | |
CY2015 | us-gaap |
Payments Of Debt Issuance Costs
PaymentsOfDebtIssuanceCosts
|
1245000 | |
CY2015 | us-gaap |
Repayments Of Long Term Debt
RepaymentsOfLongTermDebt
|
9000000 | |
CY2016 | us-gaap |
Proceeds From Payments For Other Financing Activities
ProceedsFromPaymentsForOtherFinancingActivities
|
-4000 | |
CY2015 | us-gaap |
Proceeds From Payments For Other Financing Activities
ProceedsFromPaymentsForOtherFinancingActivities
|
-2000 | |
CY2017 | us-gaap |
Net Cash Provided By Used In Financing Activities Continuing Operations
NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
|
75722000 | |
CY2016 | us-gaap |
Net Cash Provided By Used In Financing Activities Continuing Operations
NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
|
54202000 | |
CY2015 | us-gaap |
Net Cash Provided By Used In Financing Activities Continuing Operations
NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
|
77267000 | |
CY2017 | us-gaap |
Cash And Cash Equivalents Period Increase Decrease
CashAndCashEquivalentsPeriodIncreaseDecrease
|
11324000 | |
CY2016 | us-gaap |
Cash And Cash Equivalents Period Increase Decrease
CashAndCashEquivalentsPeriodIncreaseDecrease
|
665000 | |
CY2015 | us-gaap |
Cash And Cash Equivalents Period Increase Decrease
CashAndCashEquivalentsPeriodIncreaseDecrease
|
13170000 | |
CY2015Q4 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
23179000 | |
CY2017 | us-gaap |
Nature Of Operations
NatureOfOperations
|
<div> <p style="margin-bottom:0pt;margin-top:12pt;text-indent:0%;font-weight:bold;font-size:10pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">1. Nature of Business </p> <p style="margin-bottom:0pt;margin-top:6pt;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;text-indent:5.24%;">Syndax Pharmaceuticals, Inc. (the Company) is a clinical stage biopharmaceutical company developing an innovative pipeline of cancer therapies. The Company is developing its lead product candidate, entinostat, a once-weekly, oral, small molecule, Class I HDAC inhibitor, in combination with exemestane and several approved PD-1/PD-L1 antagonists. The Company’s pipeline also includes SNDX-6352, a monoclonal antibody that blocks the colony stimulating factor 1 (CSF-1) receptor, as well as a portfolio of potent and selective inhibitors targeting the binding interaction of Menin with MLLr. The Company plans to continue to leverage the technical and business expertise of our management team and scientific collaborators to license, acquire and develop additional cancer therapies to expand our pipeline.</p> <p style="margin-bottom:0pt;margin-top:12pt;text-indent:5.24%;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">In March 2016, the Company completed its initial public offering (“IPO”) whereby it sold 4,809,475 shares of common stock at the initial public offering price of $12.00 per share, which included 409,475 shares issued pursuant to the underwriters’ partial exercise of their over-allotment option to purchase additional shares of common stock. The aggregate net proceeds received by the Company from the offering were $50.5 million, net of underwriting discounts and commissions of $4.0 million and offering expenses of $3.1 million. Upon the closing of the IPO, all outstanding shares of the Company’s outstanding convertible preferred stock converted into 12,872,551 shares of common stock; and the Company’s outstanding warrant liability to purchase 357,840 shares of the Company’s common stock valued at $4.6 million was reclassified to additional paid-in capital. The shares trade on the Nasdaq Global Select Market under the symbol “SNDX.” In connection with the closing of the Company’s IPO, the Company filed an amended and restated certificate of incorporation and adopted amended and restated bylaws, both of which were approved by the Company’s board of directors and stockholders on September 28, 2015 and February 24, 2016, respectively. Pursuant to the amended and restated certificate of incorporation, the Company is now authorized to issue 100,000,000 shares of common stock and 10,000,000 shares of preferred stock. </p> <p style="margin-bottom:0pt;margin-top:12pt;text-indent:5.24%;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">In April 2017, the Company entered into a sales agreement with Cowen and Company, LLC (“Cowen”) under which the Company may issue and sell shares of our common stock having aggregate sales proceeds of up to $50.0 million from time to time through Cowen, acting as agent, in a series of one or more at-the-market (“ATM”) equity offerings. Cowen is not required to sell any specific amount but acts as our sales agent using commercially reasonable efforts consistent with its normal trading and sales practices. Shares sold pursuant to the sales agreement will be sold pursuant to a shelf registration statement, which became effective on April 20, 2017. Our common stock will be sold at prevailing market prices at the time of the sale; and as a result, prices may vary. We will pay Cowen up to 3% of the gross proceeds from any common stock sold through the sales agreement. In 2017, the Company sold 148,421 shares of Common Stock pursuant to the ATM program, at an average price of $12.45 per share for gross proceeds of $1.8 million, resulting in net proceeds of $1.7 million after deducting sales commissions and offering expenses. As of December 31, 2017, $48.2 million of Common Stock remained available for sale under the ATM program.</p> <p style="margin-bottom:0pt;margin-top:12pt;text-indent:5.24%;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">In May 2017, the Company completed a follow-on public offering whereby the Company sold 3,950,190 shares of common stock at a price of $13.25 per share, which included 200,190 shares issued pursuant to the underwriters’ partial exercise of their option to purchase additional shares of common stock. The aggregate net proceeds received by the Company from the offering were approximately $48.7 million, net of underwriting discounts and commissions and estimated offering expenses payable by the Company.</p> <p style="margin-bottom:0pt;margin-top:12pt;text-indent:5.24%;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">On October 13, 2017, the Company entered into a license agreement with Vitae Pharmaceuticals, Inc., a subsidiary of Allergan plc (“Allergan”), under which Allergan granted to the Company a worldwide, sublicenseable, exclusive license to a portfolio of preclinical, orally-available, small molecule inhibitors of the interaction of Menin with the Mixed Lineage Leukemia (“MLL”) protein (the “Menin Assets”). The Company made a nonrefundable upfront payment of $5.0 million to Allergan in the fourth quarter of 2017. The Company is developing the Menin Assets to potentially treat MLL-r driven malignancies and believes that the Menin Assets have the potential to be used to treat a genetically-defined subset of acute leukemias with chromosomal rearrangements in the MLL gene (“MLL-r”). The Company is in the process of performing a number of pre-clinical studies related to the Menin Assets.</p> <p style="margin-bottom:0pt;margin-top:0pt;text-indent:5.24%;font-size:10pt;"> </p> <p style="margin-bottom:0pt;margin-top:2pt;text-indent:5.24%;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">On October 17, 2017, the Company entered into a purchase agreement with Biotech Value Fund, L.P. (“BVF”) and certain entities affiliated with BVF (the “Purchase Agreement”). Pursuant to the Purchase Agreement, the Company issued directly to BVF in a registered direct offering (the “Offering”), 2,021,018 shares of the Company’s common stock at a price of $12.37 per share, representing the closing price of the Company’s shares on the Nasdaq Global Select Market on Friday, October 13, 2017. The net proceeds from the Offering, after deducting estimated expenses, were $24.9 million.</p> <p style="margin-bottom:0pt;margin-top:12pt;text-indent:5.24%;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">Since its inception, the Company has devoted its efforts principally to research and development and raising capital. The Company is subject to risks common to companies in the development stage, including, but not limited to, successful development of therapeutics, obtaining additional funding, protection of proprietary therapeutics, compliance with government regulations, fluctuations in operating results, dependence on key personnel and collaborative partners, and risks associated with industry changes. The Company’s long-term success is dependent upon its ability to successfully develop and market its product candidates, expand its oncology drug pipeline, earn revenue, obtain additional capital when needed, and ultimately, achieve profitable operations. The Company anticipates that it will be several years before any of its product candidates is approved, if ever, and the Company begins to generate revenue from sales of such product candidates. Accordingly, management expects to incur substantial losses on the ongoing development of its product candidates and does not expect to achieve positive cash flow from operations for the foreseeable future, if ever. As a result, the Company will continue to require additional capital to move forward with its business plan. While certain amounts of this additional capital were raised in the past, there can be no assurance that funds necessary beyond these amounts will be available in amounts or on terms sufficient to ensure ongoing operations. </p> <p style="margin-bottom:0pt;margin-top:12pt;text-indent:5.24%;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">The Company’s management believes that the cash, cash equivalents, short-term and long-term investments balances as of December 31, 2017 should enable the Company to maintain its planned operations for at least twelve months from the date these financial statements were issued. The Company’s ability to fund all of its planned operations internally beyond that date, including the completion of its ongoing and planned clinical trial activities, may be substantially dependent upon whether the Company can obtain sufficient funding on terms acceptable to the Company. Proceeds from additional capital transactions would allow the Company to accelerate and/or expand its planned research and development activities. In the event that sufficient funds were not available, the Company may be required to delay or reduce expenditures to conserve cash, which could involve scaling back or curtailing development and general and administrative activities. </p></div> | |
CY2016Q4 | us-gaap |
Other Prepaid Expense Current
OtherPrepaidExpenseCurrent
|
202000 | |
CY2017 | us-gaap |
Use Of Estimates
UseOfEstimates
|
<div> <p style="margin-bottom:0pt;margin-top:6pt;margin-left:5.22%;text-indent:0%;font-weight:bold;font-style:italic;font-size:10pt;font-family:Times New Roman;text-transform:none;font-variant: normal;">Use of Estimates </p> <p style="margin-bottom:0pt;margin-top:6pt;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;text-indent:5.24%;">The preparation of consolidated financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the date of the consolidated financial statements and the reported amounts of costs and expenses during the reporting period. The Company bases estimates and assumptions on historical experience when available and on various factors that it believes to be reasonable under the circumstances. The Company evaluates its estimates and assumptions on an ongoing basis. The Company’s actual results may differ from these estimates under different assumptions or conditions. </p></div> | |
CY2017 | us-gaap |
Concentration Risk Credit Risk
ConcentrationRiskCreditRisk
|
<div> <p style="margin-bottom:0pt;margin-top:18pt;margin-left:5.22%;text-indent:0%;font-weight:bold;font-style:italic;font-size:10pt;font-family:Times New Roman;text-transform:none;font-variant: normal;">Concentrations of Credit Risk </p> <p style="margin-bottom:0pt;margin-top:6pt;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;text-indent:5.24%;">Cash and cash equivalents, restricted cash, and short-term and long-term investments are financial instruments that potentially subject the Company to concentrations of credit risk. Substantially all of the Company’s cash, cash equivalents, and short-term and long-term investments were deposited in accounts at two financial institutions, and at times, such deposits may exceed federally insured limits. The Company has not experienced any losses in such accounts, and management believes that the Company is not exposed to significant credit risk due to the financial position of the depository institutions in which those deposits are held. The Company’s available-for-sale investments primarily consist of U.S. Treasury securities, U.S. government agency securities, corporate debt securities, certificates of deposit and overnight deposits and potentially subject the Company to concentrations of credit risk. </p></div> | |
CY2017 | us-gaap |
Guarantees Indemnifications And Warranties Policies
GuaranteesIndemnificationsAndWarrantiesPolicies
|
<div> <p style="margin-bottom:0pt;margin-top:18pt;margin-left:5.22%;text-indent:0%;font-weight:bold;font-style:italic;font-size:10pt;font-family:Times New Roman;text-transform:none;font-variant: normal;">Guarantees and Indemnifications </p> <p style="margin-bottom:0pt;margin-top:6pt;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;text-indent:5.24%;">As permitted under Delaware law, the Company indemnifies its officers, directors, and employees for certain events or occurrences that happen by reason of the relationship with, or position held at, the Company. The Company has standard indemnification arrangements under office leases (as described in Note 16) that require it to indemnify the landlord against all costs, expenses, fines, suits, claims, demands, liabilities, and actions directly resulting from any breach, violation, or nonperformance of any covenant or condition of the Company’s lease. Through December 31, 2017, the Company had not experienced any losses related to these indemnification obligations and no claims were outstanding. The Company does not expect significant claims related to these indemnification obligations, and consequently, concluded that the fair value of these obligations is negligible, and no related reserves were established. </p></div> | |
CY2016 | us-gaap |
Temporary Equity Dividends Adjustment
TemporaryEquityDividendsAdjustment
|
2598000 | |
CY2015 | us-gaap |
Temporary Equity Dividends Adjustment
TemporaryEquityDividendsAdjustment
|
10011000 | |
CY2017Q4 | us-gaap |
Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
|
108248000 | |
CY2016Q4 | us-gaap |
Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
|
81486000 | |
CY2017Q4 | us-gaap |
Deposits Assets Current
DepositsAssetsCurrent
|
1286000 | |
CY2016Q4 | us-gaap |
Deposits Assets Current
DepositsAssetsCurrent
|
1630000 | |
CY2017Q4 | us-gaap |
Supplies
Supplies
|
220000 | |
CY2016Q4 | us-gaap |
Supplies
Supplies
|
461000 | |
CY2015 | us-gaap |
Temporary Equity Accretion To Redemption Value Adjustment
TemporaryEquityAccretionToRedemptionValueAdjustment
|
69715000 | |
CY2017Q4 | us-gaap |
Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
|
466000 | |
CY2016Q4 | us-gaap |
Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
|
540000 | |
CY2017Q4 | us-gaap |
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
|
199000 | |
CY2016Q4 | us-gaap |
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
|
280000 | |
us-gaap |
Available For Sale Securities Gross Realized Gain Loss Net
AvailableForSaleSecuritiesGrossRealizedGainLossNet
|
0 | ||
CY2017Q4 | us-gaap |
Available For Sale Debt Securities Amortized Cost Basis
AvailableForSaleDebtSecuritiesAmortizedCostBasis
|
108391000 | |
CY2016Q4 | us-gaap |
Available For Sale Debt Securities Amortized Cost Basis
AvailableForSaleDebtSecuritiesAmortizedCostBasis
|
81430000 | |
CY2016Q4 | us-gaap |
Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
|
67000 | |
CY2017Q4 | us-gaap |
Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
|
143000 | |
CY2016Q4 | us-gaap |
Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
|
11000 | |
CY2017Q2 | sndx |
Payment Specified Percentage Of Gross Proceeds From Sale Of Shares
PaymentSpecifiedPercentageOfGrossProceedsFromSaleOfShares
|
0.03 | |
CY2017 | us-gaap |
Number Of Operating Segments
NumberOfOperatingSegments
|
1 | |
CY2017 | us-gaap |
Tangible Asset Impairment Charges
TangibleAssetImpairmentCharges
|
0 | |
CY2017Q4 | us-gaap |
Interest Receivable Current
InterestReceivableCurrent
|
377000 | |
CY2016Q4 | us-gaap |
Interest Receivable Current
InterestReceivableCurrent
|
306000 | |
CY2017Q4 | sndx |
Reimbursable Costs
ReimbursableCosts
|
1029000 | |
CY2016Q4 | sndx |
Reimbursable Costs
ReimbursableCosts
|
262000 | |
CY2017Q4 | us-gaap |
Prepaid Insurance
PrepaidInsurance
|
192000 | |
CY2016Q4 | us-gaap |
Prepaid Insurance
PrepaidInsurance
|
168000 | |
CY2017Q4 | us-gaap |
Other Prepaid Expense Current
OtherPrepaidExpenseCurrent
|
258000 | |
CY2017 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1
|
P7Y | |
CY2017Q4 | us-gaap |
Capital Leases Future Minimum Payments Due In Five Years
CapitalLeasesFutureMinimumPaymentsDueInFiveYears
|
0 | |
CY2017Q4 | us-gaap |
Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
|
265000 | |
CY2016Q4 | us-gaap |
Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
|
247000 | |
CY2017Q4 | us-gaap |
Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
|
2393000 | |
CY2016Q4 | us-gaap |
Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
|
1641000 | |
CY2017Q4 | sndx |
Accrued Clinical Costs Current
AccruedClinicalCostsCurrent
|
9177000 | |
CY2016Q4 | sndx |
Accrued Clinical Costs Current
AccruedClinicalCostsCurrent
|
4493000 | |
CY2017Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
158000 | |
CY2016Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
390000 | |
CY2014Q3 | us-gaap |
Debt Instrument Face Amount
DebtInstrumentFaceAmount
|
5000000 | |
CY2017Q4 | us-gaap |
Common Stock Capital Shares Reserved For Future Issuance
CommonStockCapitalSharesReservedForFutureIssuance
|
5498310 | |
CY2017 | us-gaap |
Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
|
5450000 | |
CY2016 | us-gaap |
Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
|
4708000 | |
CY2015 | us-gaap |
Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
|
3882000 | |
CY2017 | us-gaap |
Fair Value Assumptions Expected Term
FairValueAssumptionsExpectedTerm
|
P6Y7D | |
CY2016 | us-gaap |
Fair Value Assumptions Expected Term
FairValueAssumptionsExpectedTerm
|
P5Y10M6D | |
CY2015 | us-gaap |
Fair Value Assumptions Expected Term
FairValueAssumptionsExpectedTerm
|
P5Y10M20D | |
CY2017 | us-gaap |
Fair Value Assumptions Expected Volatility Rate
FairValueAssumptionsExpectedVolatilityRate
|
0.7386 | |
CY2016 | us-gaap |
Fair Value Assumptions Expected Volatility Rate
FairValueAssumptionsExpectedVolatilityRate
|
0.7140 | |
CY2015 | us-gaap |
Fair Value Assumptions Expected Volatility Rate
FairValueAssumptionsExpectedVolatilityRate
|
0.6992 | |
CY2017 | us-gaap |
Fair Value Assumptions Risk Free Interest Rate
FairValueAssumptionsRiskFreeInterestRate
|
0.0202 | |
CY2016 | us-gaap |
Fair Value Assumptions Risk Free Interest Rate
FairValueAssumptionsRiskFreeInterestRate
|
0.0141 | |
CY2015 | us-gaap |
Fair Value Assumptions Risk Free Interest Rate
FairValueAssumptionsRiskFreeInterestRate
|
0.0173 | |
CY2017 | us-gaap |
Fair Value Assumptions Expected Dividend Rate
FairValueAssumptionsExpectedDividendRate
|
0.0000 | |
CY2016 | us-gaap |
Fair Value Assumptions Expected Dividend Rate
FairValueAssumptionsExpectedDividendRate
|
0.0000 | |
CY2015 | us-gaap |
Fair Value Assumptions Expected Dividend Rate
FairValueAssumptionsExpectedDividendRate
|
0.0000 | |
CY2016Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
|
2560737 | |
CY2017 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
|
967490 | |
CY2017 | us-gaap |
Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
|
46680 | |
CY2017 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod
|
89715 | |
CY2017Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
|
3391832 | |
CY2017Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber
|
1943661 | |
CY2017Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber
|
3371831 | |
CY2016Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
|
8.97 | |
CY2017 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
|
10.22 | |
CY2017 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
|
5.93 | |
CY2017 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice
|
12.03 | |
CY2017Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
|
9.28 | |
CY2017Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice
|
8.66 | |
CY2017Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice
|
9.27 | |
CY2016 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
|
P8Y4M24D | |
CY2017 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
|
P7Y8M12D | |
CY2017 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1
|
P7Y8M12D | |
CY2016Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
|
503000 | |
CY2017Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
|
2688000 | |
CY2017Q4 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1
|
2173000 | |
CY2017Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Aggregate Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue
|
2688000 | |
CY2017 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
6.68 | |
CY2016 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
7.94 | |
CY2015 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
5.74 | |
CY2016 | us-gaap |
Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
|
441573 | |
CY2015 | us-gaap |
Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
|
41607 | |
CY2016 | us-gaap |
Stock Repurchased During Period Shares
StockRepurchasedDuringPeriodShares
|
16731 | |
CY2017 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
200000 | |
CY2016 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
3800000 | |
CY2015 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
200000 | |
CY2017 | us-gaap |
Defined Contribution Plan Employer Discretionary Contribution Amount
DefinedContributionPlanEmployerDiscretionaryContributionAmount
|
106000 | |
CY2017Q4 | us-gaap |
Operating Leases Future Minimum Payments Due
OperatingLeasesFutureMinimumPaymentsDue
|
2160000 | |
CY2017Q4 | us-gaap |
Capital Leases Future Minimum Payments Due Current
CapitalLeasesFutureMinimumPaymentsDueCurrent
|
3000 | |
CY2016 | us-gaap |
Defined Contribution Plan Employer Discretionary Contribution Amount
DefinedContributionPlanEmployerDiscretionaryContributionAmount
|
72000 | |
CY2015 | us-gaap |
Defined Contribution Plan Employer Discretionary Contribution Amount
DefinedContributionPlanEmployerDiscretionaryContributionAmount
|
33000 | |
CY2017 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
0 | |
CY2016 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
0 | |
CY2017Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
11091000 | |
CY2016Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
13744000 | |
CY2017Q4 | us-gaap |
Deferred Tax Assets In Process Research And Development
DeferredTaxAssetsInProcessResearchAndDevelopment
|
2380000 | |
CY2016Q4 | us-gaap |
Deferred Tax Assets In Process Research And Development
DeferredTaxAssetsInProcessResearchAndDevelopment
|
1739000 | |
CY2017Q4 | sndx |
Deferred Tax Assets Capitalized Startup And Costs Research And Development Costs
DeferredTaxAssetsCapitalizedStartupAndCostsResearchAndDevelopmentCosts
|
43282000 | |
CY2016Q4 | sndx |
Deferred Tax Assets Capitalized Startup And Costs Research And Development Costs
DeferredTaxAssetsCapitalizedStartupAndCostsResearchAndDevelopmentCosts
|
47048000 | |
CY2017Q4 | us-gaap |
Deferred Tax Assets Deferred Income
DeferredTaxAssetsDeferredIncome
|
3240000 | |
CY2016Q4 | us-gaap |
Deferred Tax Assets Deferred Income
DeferredTaxAssetsDeferredIncome
|
5420000 | |
CY2017Q4 | sndx |
Deferred Tax Liabilities Depreciation And Amortization
DeferredTaxLiabilitiesDepreciationAndAmortization
|
8610000 | |
CY2016Q4 | sndx |
Deferred Tax Liabilities Depreciation And Amortization
DeferredTaxLiabilitiesDepreciationAndAmortization
|
10530000 | |
CY2017Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Reserves And Accruals Accrued Liabilities
DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities
|
534000 | |
CY2016Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Reserves And Accruals Accrued Liabilities
DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities
|
604000 | |
CY2017Q4 | us-gaap |
Deferred Tax Assets Other
DeferredTaxAssetsOther
|
2530000 | |
CY2016Q4 | us-gaap |
Deferred Tax Assets Other
DeferredTaxAssetsOther
|
2298000 | |
CY2017Q4 | us-gaap |
Deferred Tax Assets Gross
DeferredTaxAssetsGross
|
54447000 | |
CY2016Q4 | us-gaap |
Deferred Tax Assets Gross
DeferredTaxAssetsGross
|
60323000 | |
CY2017Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
54447000 | |
CY2016Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
60323000 | |
CY2017 | us-gaap |
Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
|
-5900000 | |
CY2016 | us-gaap |
Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
|
13000000 | |
CY2017 | us-gaap |
Valuation Allowance Methodologies And Assumptions
ValuationAllowanceMethodologiesAndAssumptions
|
The Company has provided a valuation allowance for the full amount of the net deferred tax assets as the realization of the deferred tax assets is not determined to be more likely than not. The valuation allowance increased by $13.0 million in 2016, due to the increase in deferred tax assets, primarily due to net operating loss carryforwards and capitalized research and development costs, and decreased by $5.9 million in 2017 due to the decrease in the federal tax rate. | |
CY2017Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards Domestic
DeferredTaxAssetsOperatingLossCarryforwardsDomestic
|
44900000 | |
CY2017Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards State And Local
DeferredTaxAssetsOperatingLossCarryforwardsStateAndLocal
|
26000000 | |
CY2017 | sndx |
Deferred Tax Assets Operating Loss Carryforwards Expiration Period
DeferredTaxAssetsOperatingLossCarryforwardsExpirationPeriod
|
2037 | |
CY2017 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.34 | |
CY2017 | sndx |
Tax Cuts And Jobs Act Of2017 Accounting Complete
TaxCutsAndJobsActOf2017AccountingComplete
|
false | |
CY2017 | sndx |
Tax Cuts And Jobs Act Of2017 Incomplete Accounting Transition Tax For Accumulated Foreign Earnings Provisional Income Tax Expense Benefit
TaxCutsAndJobsActOf2017IncompleteAccountingTransitionTaxForAccumulatedForeignEarningsProvisionalIncomeTaxExpenseBenefit
|
0 | |
CY2017 | sndx |
Tax Cuts And Jobs Act Of2017 Incomplete Accounting Change In Tax Rate Provisional Income Tax Expense Benefit
TaxCutsAndJobsActOf2017IncompleteAccountingChangeInTaxRateProvisionalIncomeTaxExpenseBenefit
|
-28800000 | |
CY2017 | sndx |
Tax Cuts And Jobs Act Of2017 Incomplete Accounting Reduction In Deferred Tax Assets Valuation Allowance
TaxCutsAndJobsActOf2017IncompleteAccountingReductionInDeferredTaxAssetsValuationAllowance
|
28800000 | |
CY2017 | sndx |
Tax Cuts And Jobs Act Of2017 Incomplete Accounting Reduction In Deferred Tax Assets Valuation Allowance Net
TaxCutsAndJobsActOf2017IncompleteAccountingReductionInDeferredTaxAssetsValuationAllowanceNet
|
0 | |
CY2016Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
241000 | |
CY2015Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
241000 | |
CY2014Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
241000 | |
CY2017 | us-gaap |
Unrecognized Tax Benefits Decreases Resulting From Prior Period Tax Positions
UnrecognizedTaxBenefitsDecreasesResultingFromPriorPeriodTaxPositions
|
78000 | |
CY2016 | us-gaap |
Unrecognized Tax Benefits Decreases Resulting From Prior Period Tax Positions
UnrecognizedTaxBenefitsDecreasesResultingFromPriorPeriodTaxPositions
|
0 | |
CY2015 | us-gaap |
Unrecognized Tax Benefits Decreases Resulting From Prior Period Tax Positions
UnrecognizedTaxBenefitsDecreasesResultingFromPriorPeriodTaxPositions
|
0 | |
CY2017Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
163000 | |
CY2017Q4 | us-gaap |
Operating Leases Future Minimum Payments Due Current
OperatingLeasesFutureMinimumPaymentsDueCurrent
|
549000 | |
CY2017Q4 | us-gaap |
Operating Leases Future Minimum Payments Due In Two Years
OperatingLeasesFutureMinimumPaymentsDueInTwoYears
|
569000 | |
CY2017Q4 | us-gaap |
Operating Leases Future Minimum Payments Due In Three Years
OperatingLeasesFutureMinimumPaymentsDueInThreeYears
|
588000 | |
CY2017Q4 | us-gaap |
Operating Leases Future Minimum Payments Due In Four Years
OperatingLeasesFutureMinimumPaymentsDueInFourYears
|
395000 | |
CY2017Q4 | us-gaap |
Operating Leases Future Minimum Payments Due In Five Years
OperatingLeasesFutureMinimumPaymentsDueInFiveYears
|
59000 | |
CY2017Q4 | us-gaap |
Operating Leases Future Minimum Payments Due Thereafter
OperatingLeasesFutureMinimumPaymentsDueThereafter
|
0 | |
CY2017Q4 | us-gaap |
Capital Leases Future Minimum Payments Due In Two Years
CapitalLeasesFutureMinimumPaymentsDueInTwoYears
|
0 | |
CY2017Q4 | us-gaap |
Capital Leases Future Minimum Payments Due In Three Years
CapitalLeasesFutureMinimumPaymentsDueInThreeYears
|
0 | |
CY2017Q4 | us-gaap |
Capital Leases Future Minimum Payments Due In Four Years
CapitalLeasesFutureMinimumPaymentsDueInFourYears
|
0 | |
CY2017Q3 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
22239996 | |
CY2017Q3 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
358000 | |
CY2017Q4 | us-gaap |
Capital Leases Future Minimum Payments Due Thereafter
CapitalLeasesFutureMinimumPaymentsDueThereafter
|
0 | |
CY2017Q4 | us-gaap |
Capital Leases Future Minimum Payments Due
CapitalLeasesFutureMinimumPaymentsDue
|
3000 | |
CY2017Q4 | us-gaap |
Capital Leases Future Minimum Payments Interest Included In Payments
CapitalLeasesFutureMinimumPaymentsInterestIncludedInPayments
|
0 | |
CY2017Q4 | us-gaap |
Capital Leases Future Minimum Payments Present Value Of Net Minimum Payments
CapitalLeasesFutureMinimumPaymentsPresentValueOfNetMinimumPayments
|
3000 | |
CY2017 | us-gaap |
Operating Leases Rent Expense Net
OperatingLeasesRentExpenseNet
|
800000 | |
CY2016 | us-gaap |
Operating Leases Rent Expense Net
OperatingLeasesRentExpenseNet
|
400000 | |
CY2015 | us-gaap |
Operating Leases Rent Expense Net
OperatingLeasesRentExpenseNet
|
100000 | |
CY2016 | us-gaap |
Interest Paid
InterestPaid
|
2000 | |
CY2015 | us-gaap |
Interest Paid
InterestPaid
|
688000 | |
CY2015 | us-gaap |
Debt Conversion Converted Instrument Amount1
DebtConversionConvertedInstrumentAmount1
|
5211000 | |
CY2017 | us-gaap |
Debt Issuance Costs Incurred During Noncash Or Partial Noncash Transaction
DebtIssuanceCostsIncurredDuringNoncashOrPartialNoncashTransaction
|
50000 | |
CY2015 | us-gaap |
Debt Issuance Costs Incurred During Noncash Or Partial Noncash Transaction
DebtIssuanceCostsIncurredDuringNoncashOrPartialNoncashTransaction
|
376000 | |
CY2015 | us-gaap |
Capital Expenditures Incurred But Not Yet Paid
CapitalExpendituresIncurredButNotYetPaid
|
27000 | |
CY2017 | sndx |
Vesting Of Restricted Stock Value
VestingOfRestrictedStockValue
|
59000 | |
CY2016 | sndx |
Vesting Of Restricted Stock Value
VestingOfRestrictedStockValue
|
42000 | |
CY2015 | sndx |
Vesting Of Restricted Stock Value
VestingOfRestrictedStockValue
|
14000 | |
CY2016 | sndx |
Reclassification Of Common Stock Warrant Liability To Additional Paid In Capital
ReclassificationOfCommonStockWarrantLiabilityToAdditionalPaidInCapital
|
4551000 | |
CY2016 | us-gaap |
Conversion Of Stock Amount Converted1
ConversionOfStockAmountConverted1
|
328941000 | |
CY2017Q1 | us-gaap |
Licenses Revenue
LicensesRevenue
|
305000 | |
CY2017Q2 | us-gaap |
Licenses Revenue
LicensesRevenue
|
305000 | |
CY2017Q3 | us-gaap |
Licenses Revenue
LicensesRevenue
|
305000 | |
CY2017Q4 | us-gaap |
Licenses Revenue
LicensesRevenue
|
1193000 | |
CY2017Q1 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
9552000 | |
CY2017Q2 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
9862000 | |
CY2017Q3 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
12188000 | |
CY2017Q4 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
16599000 | |
CY2017Q1 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
3930000 | |
CY2017Q2 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
4285000 | |
CY2017Q3 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
3563000 | |
CY2017Q4 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
4083000 | |
CY2017Q1 | us-gaap |
Operating Expenses
OperatingExpenses
|
13482000 | |
CY2017Q2 | us-gaap |
Operating Expenses
OperatingExpenses
|
14147000 | |
CY2017Q3 | us-gaap |
Operating Expenses
OperatingExpenses
|
15751000 | |
CY2017Q4 | us-gaap |
Operating Expenses
OperatingExpenses
|
20682000 | |
CY2017Q1 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-13177000 | |
CY2017Q2 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-13842000 | |
CY2017Q3 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-15446000 | |
CY2017Q4 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-19489000 | |
CY2017Q1 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
206000 | |
CY2017Q2 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
203000 | |
CY2017Q4 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
385000 | |
CY2017Q1 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-12971000 | |
CY2017Q2 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-13639000 | |
CY2017Q3 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-15088000 | |
CY2017Q4 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-19104000 | |
CY2017Q1 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.71 | |
CY2017Q2 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.70 | |
CY2017Q3 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.68 | |
CY2017Q4 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.80 | |
CY2017Q1 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
18231602 | |
CY2017Q2 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
19497581 | |
CY2017Q4 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
23943241 | |
CY2016Q4 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
2972000 | |
CY2016Q1 | us-gaap |
Operating Expenses
OperatingExpenses
|
9058000 | |
CY2016Q2 | us-gaap |
Operating Expenses
OperatingExpenses
|
8939000 | |
CY2016Q3 | us-gaap |
Operating Expenses
OperatingExpenses
|
15543000 | |
CY2016Q4 | us-gaap |
Operating Expenses
OperatingExpenses
|
11446000 | |
CY2016Q1 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-8753000 | |
CY2016Q1 | us-gaap |
Licenses Revenue
LicensesRevenue
|
305000 | |
CY2016Q2 | us-gaap |
Licenses Revenue
LicensesRevenue
|
305000 | |
CY2016Q3 | us-gaap |
Licenses Revenue
LicensesRevenue
|
305000 | |
CY2016Q4 | us-gaap |
Licenses Revenue
LicensesRevenue
|
305000 | |
CY2016Q1 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
4786000 | |
CY2016Q2 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
6131000 | |
CY2016Q3 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
12274000 | |
CY2016Q4 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
8474000 | |
CY2016Q1 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
4272000 | |
CY2016Q2 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
2808000 | |
CY2016Q3 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
3269000 | |
CY2016Q2 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-8634000 | |
CY2016Q3 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-15238000 | |
CY2016Q4 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-11141000 | |
CY2016Q1 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
-1577000 | |
CY2016Q2 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
276000 | |
CY2016Q3 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
269000 | |
CY2016Q4 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
326000 | |
CY2016Q1 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-10330000 | |
CY2016Q2 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-8358000 | |
CY2016Q3 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-14969000 | |
CY2016Q4 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-10815000 | |
CY2016Q1 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-2.85 | |
CY2016Q2 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.47 | |
CY2016Q3 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.84 | |
CY2016Q4 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.59 | |
CY2016Q1 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
4541536 | |
CY2016Q2 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
17769514 | |
CY2016Q3 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
17899481 | |
CY2016Q4 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
18193027 |