2018 Q1 Form 10-K Financial Statement

#000156459018004911 Filed on March 08, 2018

View on sec.gov

Income Statement

Concept 2018 Q1 2017 Q4 2017
Revenue $379.0K $1.193M $2.108M
YoY Change 24.26% 291.15% 72.79%
Cost Of Revenue
YoY Change
Gross Profit
YoY Change
Gross Profit Margin
Selling, General & Admin $4.790M $4.080M $15.86M
YoY Change 21.88% 37.37% 19.07%
% of Gross Profit
Research & Development $15.34M $16.60M $48.20M
YoY Change 60.58% 95.88% 52.22%
% of Gross Profit
Depreciation & Amortization $150.0K $76.00K
YoY Change 66.67% -14.61%
% of Gross Profit
Operating Expenses $20.13M $20.68M $64.06M
YoY Change 49.31% 80.69% 42.4%
Operating Profit -$19.75M -$19.49M -$61.95M
YoY Change 49.89% 74.93% 41.56%
Interest Expense $475.0K $460.0K $1.421M
YoY Change 83.4% 70.37% 48.64%
% of Operating Profit
Other Income/Expense, Net $353.0K $385.0K $1.152M
YoY Change 71.36% 18.1% -263.17%
Pretax Income -$19.40M -$19.10M -$60.80M
YoY Change 49.58% 76.52% 36.72%
Income Tax $0.00 $0.00 $0.00
% Of Pretax Income
Net Earnings -$19.40M -$19.10M -$60.80M
YoY Change 49.55% 76.64% 36.72%
Net Earnings / Revenue -5118.21% -1601.34% -2884.35%
Basic Earnings Per Share
Diluted Earnings Per Share -$792.5K -$796.5K -$2.895M
COMMON SHARES
Basic Shares Outstanding 24.70M 24.39M shares
Diluted Shares Outstanding

Balance Sheet

Concept 2018 Q1 2017 Q4 2017
SHORT-TERM ASSETS
Cash & Short-Term Investments $114.0M $131.3M $131.3M
YoY Change 19.75% 22.71% 22.71%
Cash & Equivalents $28.20M $35.17M $35.20M
Short-Term Investments $86.00M $96.10M $96.10M
Other Short-Term Assets $5.000M $1.800M $1.800M
YoY Change 212.5% 50.0% 50.0%
Inventory
Prepaid Expenses
Receivables
Other Receivables
Total Short-Term Assets $119.3M $133.4M $133.4M
YoY Change 22.92% 22.98% 22.95%
LONG-TERM ASSETS
Property, Plant & Equipment $400.0K $267.0K $300.0K
YoY Change 70.94% 2.69% 0.0%
Goodwill
YoY Change
Intangibles
YoY Change
Long-Term Investments $3.200M $3.200M
YoY Change
Other Assets $200.0K $231.0K $200.0K
YoY Change -46.81% -4.94% 0.0%
Total Long-Term Assets $700.0K $3.744M $3.800M
YoY Change 14.75% 644.33% 660.0%
TOTAL ASSETS
Total Short-Term Assets $119.3M $133.4M $133.4M
Total Long-Term Assets $700.0K $3.744M $3.800M
Total Assets $120.0M $137.2M $137.2M
YoY Change 22.87% 25.84% 25.87%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable $2.600M $2.232M $2.200M
YoY Change -5.14% -6.02% -8.33%
Accrued Expenses $12.80M $12.00M $12.00M
YoY Change 82.86% 76.47% 76.47%
Deferred Revenue $1.573M
YoY Change
Short-Term Debt $0.00 $0.00 $0.00
YoY Change
Long-Term Debt Due
YoY Change
Total Short-Term Liabilities $16.90M $15.80M $15.80M
YoY Change 53.79% 52.4% 51.92%
LONG-TERM LIABILITIES
Long-Term Debt $0.00 $0.00 $0.00
YoY Change
Other Long-Term Liabilities $16.10M $310.0K $17.10M
YoY Change 10778.38% 7.64% 17.93%
Total Long-Term Liabilities $16.10M $17.07M $17.10M
YoY Change 14.48% 17.65% 17.93%
TOTAL LIABILITIES
Total Short-Term Liabilities $16.90M $15.80M $15.80M
Total Long-Term Liabilities $16.10M $17.07M $17.10M
Total Liabilities $33.00M $32.87M $32.90M
YoY Change 31.73% 32.13% 32.13%
SHAREHOLDERS EQUITY
Retained Earnings -$366.1M
YoY Change 19.92%
Common Stock $470.6M
YoY Change 20.85%
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity $86.95M $104.3M $104.3M
YoY Change
Total Liabilities & Shareholders Equity $120.0M $137.2M $137.2M
YoY Change 22.87% 25.84% 25.87%

Cashflow Statement

Concept 2018 Q1 2017 Q4 2017
OPERATING ACTIVITIES
Net Income -$19.40M -$19.10M -$60.80M
YoY Change 49.55% 76.64% 36.72%
Depreciation, Depletion And Amortization $150.0K $76.00K
YoY Change 66.67% -14.61%
Cash From Operating Activities -$19.87M -$12.72M -$47.37M
YoY Change 56.83% 22.07% 34.74%
INVESTING ACTIVITIES
Capital Expenditures $173.0K -$40.00K $84.00K
YoY Change -67.82%
Acquisitions
YoY Change
Other Investing Activities $12.82M $1.590M -$16.99M
YoY Change 15.91% -92.55% -6.24%
Cash From Investing Activities $12.64M $1.550M -$17.07M
YoY Change 14.32% -92.73% -6.62%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net $24.90M
YoY Change
Debt Paid & Issued, Net
YoY Change
Cash From Financing Activities 33.00K 25.61M 75.72M
YoY Change -72.5% 14964.71% 39.7%
NET CHANGE
Cash From Operating Activities -19.87M -12.72M -47.37M
Cash From Investing Activities 12.64M 1.550M -17.07M
Cash From Financing Activities 33.00K 25.61M 75.72M
Net Change In Cash -7.193M 14.44M 11.28M
YoY Change 367.99% 30.32% 1380.18%
FREE CASH FLOW
Cash From Operating Activities -$19.87M -$12.72M -$47.37M
Capital Expenditures $173.0K -$40.00K $84.00K
Free Cash Flow -$20.04M -$12.68M -$47.46M
YoY Change 58.19% 21.69% 33.99%

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<div> <p style="margin-bottom:0pt;margin-top:12pt;text-indent:0%;font-weight:bold;font-size:10pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">1. Nature of Business </p> <p style="margin-bottom:0pt;margin-top:6pt;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;text-indent:5.24%;">Syndax Pharmaceuticals, Inc. (the Company) is a clinical stage biopharmaceutical company developing an innovative pipeline of cancer therapies. The Company is developing its lead product candidate, entinostat, a once-weekly, oral, small molecule, Class I HDAC inhibitor, in combination with exemestane and several approved PD-1/PD-L1 antagonists. The Company&#8217;s pipeline also includes SNDX-6352, a monoclonal antibody that blocks the colony stimulating factor 1 (CSF-1) receptor, as well as a portfolio of potent and selective inhibitors targeting the binding interaction of Menin with MLLr. The Company plans to continue to leverage the technical and business expertise of our management team and scientific collaborators to license, acquire and develop additional cancer therapies to expand our pipeline.</p> <p style="margin-bottom:0pt;margin-top:12pt;text-indent:5.24%;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">In March 2016, the Company completed its initial public offering (&#8220;IPO&#8221;) whereby it sold 4,809,475 shares of common stock at the initial public offering price of $12.00 per share, which included 409,475 shares issued pursuant to the underwriters&#8217; partial exercise of their over-allotment option to purchase additional shares of common stock. The aggregate net proceeds received by the Company from the offering were $50.5 million, net of underwriting discounts and commissions of $4.0 million and offering expenses of $3.1 million. Upon the closing of the IPO, all outstanding shares of the Company&#8217;s outstanding convertible preferred stock converted into 12,872,551 shares of common stock; and the Company&#8217;s outstanding warrant liability to purchase 357,840 shares of the Company&#8217;s common stock valued at $4.6 million was reclassified to additional paid-in capital. The shares trade on the Nasdaq Global Select Market under the symbol &#8220;SNDX.&#8221;&#160;In connection with the closing of the Company&#8217;s IPO, the Company filed an amended and restated certificate of incorporation and adopted amended and restated bylaws, both of which were approved by the Company&#8217;s board of directors and stockholders on September&#160;28, 2015 and February&#160;24, 2016, respectively. Pursuant to the amended and restated certificate of incorporation, the Company is now authorized to issue 100,000,000 shares of common stock and 10,000,000 shares of preferred stock. </p> <p style="margin-bottom:0pt;margin-top:12pt;text-indent:5.24%;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">In April 2017, the Company entered into a sales agreement with Cowen and Company, LLC (&#8220;Cowen&#8221;) under which the Company may issue and sell shares of our common stock having aggregate sales proceeds of up to $50.0 million from time to time through Cowen, acting as agent, in a series of one or more at-the-market (&#8220;ATM&#8221;) equity offerings. Cowen is not required to sell any specific amount but acts as our sales agent using commercially reasonable efforts consistent with its normal trading and sales practices. Shares sold pursuant to the sales agreement will be sold pursuant to a shelf registration statement, which became effective on April 20, 2017. Our common stock will be sold at prevailing market prices at the time of the sale; and as a result, prices may vary. We will pay Cowen up to 3% of the gross proceeds from any common stock sold through the sales agreement. In 2017, the Company sold 148,421 shares of Common Stock pursuant to the ATM program, at an average price of $12.45 per share for gross proceeds of $1.8 million, resulting in net proceeds of $1.7 million after deducting sales commissions and offering expenses. As of December 31, 2017, $48.2 million of Common Stock remained available for sale under the ATM program.</p> <p style="margin-bottom:0pt;margin-top:12pt;text-indent:5.24%;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">In May 2017, the Company completed a follow-on public offering whereby the Company sold 3,950,190 shares of common stock at a price of $13.25 per share, which included 200,190 shares issued pursuant to the underwriters&#8217; partial exercise of their option to purchase additional shares of common stock. The aggregate net proceeds received by the Company from the offering were approximately $48.7 million, net of underwriting discounts and commissions and estimated offering expenses payable by the Company.</p> <p style="margin-bottom:0pt;margin-top:12pt;text-indent:5.24%;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">On October 13, 2017, the Company entered into a license agreement with Vitae Pharmaceuticals, Inc., a subsidiary of Allergan plc (&#8220;Allergan&#8221;), under which Allergan granted to the Company a worldwide, sublicenseable, exclusive license to a portfolio of preclinical, orally-available, small molecule inhibitors of the interaction of Menin with the Mixed Lineage Leukemia (&#8220;MLL&#8221;) protein (the &#8220;Menin Assets&#8221;). The Company made a nonrefundable upfront payment of $5.0 million to Allergan in the fourth quarter of 2017. The Company is developing the Menin Assets to potentially treat MLL-r driven malignancies and believes that the Menin Assets have the potential to be used to treat a genetically-defined subset of acute leukemias with chromosomal rearrangements in the MLL gene (&#8220;MLL-r&#8221;). The Company is in the process of performing a number of pre-clinical studies related to the Menin Assets.</p> <p style="margin-bottom:0pt;margin-top:0pt;text-indent:5.24%;font-size:10pt;">&nbsp;</p> <p style="margin-bottom:0pt;margin-top:2pt;text-indent:5.24%;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">On October 17, 2017, the Company entered into a purchase agreement with Biotech Value Fund, L.P. (&#8220;BVF&#8221;) and certain entities affiliated with BVF (the &#8220;Purchase Agreement&#8221;). Pursuant to the Purchase Agreement, the Company issued directly to BVF in a registered direct offering (the &#8220;Offering&#8221;), 2,021,018 shares of the Company&#8217;s common stock at a price of $12.37 per share, representing the closing price of the Company&#8217;s shares on the Nasdaq Global Select Market on Friday, October 13, 2017. The net proceeds from the Offering, after deducting estimated expenses, were $24.9 million.</p> <p style="margin-bottom:0pt;margin-top:12pt;text-indent:5.24%;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">Since its inception, the Company has devoted its efforts principally to research and development and raising capital. The Company is subject to risks common to companies in the development stage, including, but not limited to, successful development of therapeutics, obtaining additional funding, protection of proprietary therapeutics, compliance with government regulations, fluctuations in operating results, dependence on key personnel and collaborative partners, and risks associated with industry changes. The Company&#8217;s long-term success is dependent upon its ability to successfully develop and market its product candidates, expand its oncology drug pipeline, earn revenue, obtain additional capital when needed, and ultimately, achieve profitable operations. The Company anticipates that it will be several years before any of its product candidates is approved, if ever, and the Company begins to generate revenue from sales of such product candidates. Accordingly, management expects to incur substantial losses on the ongoing development of its product candidates and does not expect to achieve positive cash flow from operations for the foreseeable future, if ever. As a result, the Company will continue to require additional capital to move forward with its business plan. While certain amounts of this additional capital were raised in the past, there can be no assurance that funds necessary beyond these amounts will be available in amounts or on terms sufficient to ensure ongoing operations. </p> <p style="margin-bottom:0pt;margin-top:12pt;text-indent:5.24%;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">The Company&#8217;s management believes that the cash, cash equivalents, short-term and long-term investments balances as of December&#160;31, 2017 should enable the Company to maintain its planned operations for at least twelve&#160;months from the date these financial statements were issued. The Company&#8217;s ability to fund all of its planned operations internally beyond that date, including the completion of its ongoing and planned clinical trial activities, may be substantially dependent upon whether the Company can obtain sufficient funding on terms acceptable to the Company. Proceeds from additional capital transactions would allow the Company to accelerate and/or expand its planned research and development activities. In the event that sufficient funds were not available, the Company may be required to delay or reduce expenditures to conserve cash, which could involve scaling back or curtailing development and general and administrative activities. </p></div>
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<div> <p style="margin-bottom:0pt;margin-top:6pt;margin-left:5.22%;text-indent:0%;font-weight:bold;font-style:italic;font-size:10pt;font-family:Times New Roman;text-transform:none;font-variant: normal;">Use of Estimates </p> <p style="margin-bottom:0pt;margin-top:6pt;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;text-indent:5.24%;">The preparation of consolidated financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the date of the consolidated financial statements and the reported amounts of costs and expenses during the reporting period. The Company bases estimates and assumptions on historical experience when available and on various factors that it believes to be reasonable under the circumstances. The Company evaluates its estimates and assumptions on an ongoing basis. The Company&#8217;s actual results may differ from these estimates under different assumptions or conditions. </p></div>
CY2017 us-gaap Concentration Risk Credit Risk
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<div> <p style="margin-bottom:0pt;margin-top:18pt;margin-left:5.22%;text-indent:0%;font-weight:bold;font-style:italic;font-size:10pt;font-family:Times New Roman;text-transform:none;font-variant: normal;">Concentrations of Credit Risk </p> <p style="margin-bottom:0pt;margin-top:6pt;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;text-indent:5.24%;">Cash and cash equivalents, restricted cash, and short-term and long-term investments are financial instruments that potentially subject the Company to concentrations of credit risk. Substantially all of the Company&#8217;s cash, cash equivalents, and short-term and long-term investments were deposited in accounts at two financial institutions, and at times, such deposits may exceed federally insured limits. The Company has not experienced any losses in such accounts, and management believes that the Company is not exposed to significant credit risk due to the financial position of the depository institutions in which those deposits are held. The Company&#8217;s available-for-sale investments primarily consist of U.S. Treasury securities, U.S. government agency securities, corporate debt securities, certificates of deposit and overnight deposits and potentially subject the Company to concentrations of credit risk. </p></div>
CY2017 us-gaap Guarantees Indemnifications And Warranties Policies
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<div> <p style="margin-bottom:0pt;margin-top:18pt;margin-left:5.22%;text-indent:0%;font-weight:bold;font-style:italic;font-size:10pt;font-family:Times New Roman;text-transform:none;font-variant: normal;">Guarantees and Indemnifications </p> <p style="margin-bottom:0pt;margin-top:6pt;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;text-indent:5.24%;">As permitted under Delaware law, the Company indemnifies its officers, directors, and employees for certain events or occurrences that happen by reason of the relationship with, or position held at, the Company. The Company has standard indemnification arrangements under office leases (as described in Note 16) that require it to indemnify the landlord against all costs, expenses, fines, suits, claims, demands, liabilities, and actions directly resulting from any breach, violation, or nonperformance of any covenant or condition of the Company&#8217;s lease. Through December&#160;31, 2017, the Company had not experienced any losses related to these indemnification obligations and no claims were outstanding. The Company does not expect significant claims related to these indemnification obligations, and consequently, concluded that the fair value of these obligations is negligible, and no related reserves were established. </p></div>
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3000
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800000
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5211000
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CY2015 sndx Vesting Of Restricted Stock Value
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CY2016 sndx Reclassification Of Common Stock Warrant Liability To Additional Paid In Capital
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CY2016 us-gaap Conversion Of Stock Amount Converted1
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