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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net income (loss) | |||||
| Adjustments to reconcile net income (loss) to net cash used in operating activities: | |||||
| Depreciation and amortization | |||||
| Non-cash lease cost | |||||
| Impairment of assets | |||||
| Share-based compensation | |||||
| Unrealized foreign currency transaction (gain) loss | |||||
| Accretion of premium (discount) on marketable securities | |||||
| Change in fair value of derivative liabilities | |||||
| Non-cash interest expense associated with the sale of future royalties | |||||
| Loss on extinguishment of liability related to the sale of future royalties | |||||
| Changes in operating assets and liabilities: | |||||
| Collaboration receivable, current and non-current - related party | |||||
| Other receivables | |||||
| Prepaid expenses and other current assets | |||||
| Other assets | |||||
| Accounts payable | |||||
| Accrued expenses and other current liabilities | |||||
| Deferred revenue | |||||
| Deferred revenue - related party | |||||
| Other long-term liabilities | |||||
| Operating lease liabilities | |||||
| Income taxes payable | |||||
| Net cash used in operating activities | |||||
| Purchases of marketable securities | |||||
| Proceeds from maturities of marketable securities | |||||
| Net cash provided by investing activities | |||||
| Cash flows from financing activities: | |||||
| Repayment of liability related to the sale of future royalties | |||||
| Proceeds from the issuance of common stock, net of issuance costs | |||||
| Proceeds from the issuance of common stock, net of commissions | |||||
| Proceeds from the issuance of common stock related to the GSK Share Purchase Agreement | |||||
| Total proceeds from the issuance of common stock, net of issuance costs | |||||
| Proceeds from stock option exercises | |||||
| Net cash provided by financing activities | |||||
| Net decrease in cash and cash equivalents | |||||
| Cash and cash equivalents at beginning of period | |||||
| Cash and cash equivalents at end of period | |||||
| Supplemental disclosure of cash flow information | |||||
| Cash paid for income taxes | |||||
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