| Insider Name | Current Shares | Net Change (1yr) | Buy/Sell Ratio |
|---|---|---|---|
| MANAGEMENT COMPANY, L.P. (SERIES C) DEERFIELD | 4,887,254 | -370,075 | - |
| Pratik Shah | 4,574,554 | -220,000 | ∞ |
| Richard E Lowenthal | 875,000 | +825,000 | 17.5 |
| Venture Investments, LLC Alexandria | 699,412 | 0 | - |
| Alexander A Fitzpatrick | 240,000 | +240,000 | ∞ |
| Eric Karas | 240,000 | +240,000 | 9.0 |
| Justin Chakma | 240,000 | +240,000 | 9.0 |
| Brian Dorsey | 240,000 | +240,000 | 12.0 |
| Kathleen D. Scott | 240,000 | +240,000 | 20.2 |
| Sarina Tanimoto | 240,000 | +190,000 | 4.8 |
| Thilo Schroeder | 238,096 | 0 | - |
| Jonathan Piazza | 69,225 | 0 | - |
| Valerie Odegard | 61,639 | 0 | - |
| Naomi Hunder | 54,427 | 0 | - |
| Management Group XII, L.L.C. Presidio | 47,619 | 0 | - |
| Russ Hawkinson | 37,251 | 0 | - |
| Saqib Islam | 30,000 | +30,000 | ∞ |
| Rajeev Dadoo | 30,000 | +30,000 | ∞ |
| Peter A. Thompson | 30,000 | +30,000 | ∞ |
| Michael Kelly | 30,000 | +30,000 | ∞ |
| Capital Healthcare Fund LP RA | 30,000 | +30,000 | ∞ |
| PHILLIP M SCHNEIDER | 30,000 | +30,000 | ∞ |
| BRENT L SAUNDERS | 30,000 | +30,000 | ∞ |
| Laura Shawver | 30,000 | +30,000 | ∞ |
| Maria Koehler | 18,000 | 0 | - |
| Andrew Kenneth William Powell | 18,000 | 0 | - |
| VICKIE L CAPPS | 18,000 | 0 | - |
| JONATHAN D ROOT | 18,000 | 0 | - |
| ROBERT HERSHBERG | 18,000 | 0 | - |
| ADVISORS LLC ORBIMED | 0 | 0 | - |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Sarina Tanimoto | Jan 05 |
Grant/Award Acquisition (A)
Compensation/Award
|
240,000 | +240,000 | $0.00 | +$0 |
| Eric Karas | Jan 05 |
Grant/Award Acquisition (A)
Compensation/Award
|
240,000 | +240,000 | $0.00 | +$0 |
| Justin Chakma | Jan 05 |
Grant/Award Acquisition (A)
Compensation/Award
|
240,000 | +240,000 | $0.00 | +$0 |
| Kathleen D. Scott | Jan 05 |
Grant/Award Acquisition (A)
Compensation/Award
|
240,000 | +240,000 | $0.00 | +$0 |
| Alexander A Fitzpatrick | Jan 05 |
Grant/Award Acquisition (A)
Compensation/Award
|
240,000 | +240,000 | $0.00 | +$0 |
| Brian Dorsey | Jan 05 |
Grant/Award Acquisition (A)
Compensation/Award
|
240,000 | +240,000 | $0.00 | +$0 |
| Richard E Lowenthal | Jan 05 |
Grant/Award Acquisition (A)
Compensation/Award
|
875,000 | +875,000 | $0.00 | +$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Brian Dorsey | Nov 14 |
Option Exercise/Conversion (M)
Compensation/Award
|
32,617 | +21,828 | $0.64 | +$13,969 |
| Brian Dorsey | Nov 14 |
Open Market Sale (S)
Market Sale
|
10,789 | -21,828 | $8.71 | -$190,049 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Justin Chakma | Nov 14 |
Option Exercise/Conversion (M)
Compensation/Award
|
166,380 | +30,000 | $0.84 | +$25,200 |
| Justin Chakma | Nov 14 |
Open Market Sale (S)
Market Sale
|
136,380 | -30,000 | $8.91 | -$267,357 |
| Pratik Shah | Nov 14 |
Gift (G)
Non-Market Transfer
|
4,574,554 | -250,000 | $0.00 | -$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Kathleen D. Scott | Aug 22 |
Open Market Sale (S)
Market Sale
|
10,042 | -12,500 | $15.00 | -$187,500 |
| Kathleen D. Scott | Aug 22 |
Option Exercise/Conversion (M)
Compensation/Award
|
22,542 | +12,500 | $1.50 | +$18,750 |
| Richard E Lowenthal | Aug 22 |
Open Market Sale (S)
Market Sale
|
1,196,494 | -50,000 | $14.49 | -$724,345 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Sarina Tanimoto | Aug 21 |
Open Market Sale (S)
Market Sale
|
1,247,447 | -37,656 | $14.09 | -$530,625 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Sarina Tanimoto | Aug 21 |
Open Market Sale (S)
Market Sale
|
1,285,103 | -12,344 | $14.03 | -$173,129 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Eric Karas | Jul 03 |
Open Market Sale (S)
Market Sale
|
10,315 | -15,000 | $16.99 | -$254,860 |
| Eric Karas | Jul 03 |
Option Exercise/Conversion (M)
Compensation/Award
|
25,315 | +15,000 | $1.50 | +$22,500 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| MANAGEMENT COMPANY, L.P. (SERIES C) DEERFIELD | Jul 01 |
Open Market Sale (S)
Market Sale
|
4,887,254 | -370,075 | $18.46 | -$6,831,584 |
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