| Insider Name | Current Shares | Net Change (1yr) | Buy/Sell Ratio |
|---|---|---|---|
| Tree Partners IV, L.P. Apple | 17,161,713 | 0 | - |
| III GP, Ltd. ATP | 16,786,713 | 0 | - |
| Horizon Enterprise Ltd Blue | 3,906,181 | 0 | - |
| INVESTMENTS, LP RTW | 3,544,248 | 0 | - |
| RODERICK WONG | 3,455,809 | 0 | - |
| Group, LLC Redmile | 671,808 | 0 | - |
| Adrian R. Krainer | 283,302 | -100,734 | - |
| IAN F SMITH | 193,000 | +763,000 | ∞ |
| Edward M. MD Kaye | 84,624 | -175,283 | 1.05 |
| Stephen J Tulipano | 60,000 | 0 | - |
| Gene Liau | 40,800 | 0 | - |
| Barry Ticho | 38,864 | +81,959 | 2.84 |
| ARTHUR TZIANABOS | 31,339 | -400 | 0.91 |
| Clare Kahn | 30,782 | +30,782 | ∞ |
| Julie Smith | 29,747 | 0 | - |
| Seth Loring Harrison | 29,747 | 0 | - |
| Jennifer Burstein | 29,747 | 0 | - |
| Garry E Menzel | 29,747 | 0 | - |
| Samuel W. Hall | 29,555 | 0 | - |
| Jonathan Allan | 20,144 | +48,488 | 1.71 |
| Jason Hoitt | 10,445 | +79,205 | 29.34 |
| Thomas Leggett | 10,381 | +71,303 | 21.69 |
| ARTHUR A LEVIN | 4,237 | +3,027 | 6.0 |
| Huw M. Nash | 33 | 0 | - |
| Life Science Ventures, L.P. ATP | 0 | 0 | - |
| Robin A. Walker | 0 | 0 | - |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Clare Kahn | Apr 07 |
Grant/Award Acquisition (A)
Compensation/Award
|
30,782 | +30,782 | $0.00 | +$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Barry Ticho | Apr 03 |
Open Market Sale (S)
Market Sale
|
38,864 | -1,838 | $32.66 | -$60,029 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Jonathan Allan | Mar 24 |
Open Market Sale (S)
Market Sale
|
20,144 | -8,692 | $33.64 | -$292,358 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Barry Ticho | Mar 19 |
Option Exercise/Conversion (M)
Compensation/Award
|
42,163 | +1,365 | $2.19 | +$2,989 |
| Barry Ticho | Mar 19 |
Open Market Sale (S)
Market Sale
|
40,702 | -1,461 | $29.99 | -$43,815 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Jonathan Allan | Mar 19 |
Open Market Sale (S)
Market Sale
|
29,242 | -4,222 | $31.28 | -$132,080 |
| Barry Ticho | Mar 19 |
Open Market Sale (S)
Market Sale
|
41,384 | -6,100 | $31.28 | -$190,831 |
| Jason Hoitt | Mar 19 |
Open Market Sale (S)
Market Sale
|
10,445 | -1,762 | $31.28 | -$55,122 |
| Thomas Leggett | Mar 19 |
Open Market Sale (S)
Market Sale
|
10,381 | -2,173 | $31.28 | -$67,979 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Jonathan Allan | Mar 19 |
Open Market Sale (S)
Market Sale
|
35,255 | -2,476 | $32.74 | -$81,062 |
| Barry Ticho | Mar 19 |
Open Market Sale (S)
Market Sale
|
50,071 | -3,577 | $32.74 | -$117,108 |
| Thomas Leggett | Mar 19 |
Open Market Sale (S)
Market Sale
|
13,476 | -1,274 | $32.74 | -$41,709 |
| Jason Hoitt | Mar 19 |
Open Market Sale (S)
Market Sale
|
12,955 | -1,033 | $32.74 | -$33,819 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Edward M. MD Kaye | Mar 17 |
Option Exercise/Conversion (M)
Compensation/Award
|
84,624 | +35,500 | $0.00 | +$0 |
| Jonathan Allan | Mar 17 |
Option Exercise/Conversion (M)
Compensation/Award
|
19,731 | +7,475 | $0.00 | +$0 |
| Barry Ticho | Mar 17 |
Option Exercise/Conversion (M)
Compensation/Award
|
32,898 | +13,100 | $0.00 | +$0 |
| Thomas Leggett | Mar 17 |
Option Exercise/Conversion (M)
Compensation/Award
|
14,750 | +14,750 | $0.00 | +$0 |
| Jason Hoitt | Mar 17 |
Option Exercise/Conversion (M)
Compensation/Award
|
13,988 | +10,000 | $0.00 | +$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| ARTHUR A LEVIN | Mar 17 |
Open Market Sale (S)
Market Sale
|
4,237 | -605 | $36.80 | -$22,264 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| ARTHUR TZIANABOS | Mar 12 |
Option Exercise/Conversion (M)
Compensation/Award
|
35,694 | +3,955 | $8.33 | +$32,945 |
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