2021 Q1 Form 10-Q Financial Statement
#000156459021024498 Filed on May 06, 2021
Income Statement
| Concept | 2021 Q1 | 2020 Q1 |
|---|---|---|
| Revenue | $4.827M | $2.379M |
| YoY Change | 102.9% | 424.01% |
| Cost Of Revenue | ||
| YoY Change | ||
| Gross Profit | ||
| YoY Change | ||
| Gross Profit Margin | ||
| Selling, General & Admin | $5.740M | $5.150M |
| YoY Change | 11.46% | 5.75% |
| % of Gross Profit | ||
| Research & Development | $20.03M | $14.57M |
| YoY Change | 37.48% | 15.98% |
| % of Gross Profit | ||
| Depreciation & Amortization | $666.0K | $678.0K |
| YoY Change | -1.77% | 31.14% |
| % of Gross Profit | ||
| Operating Expenses | $25.77M | $19.72M |
| YoY Change | 30.69% | 13.15% |
| Operating Profit | -$20.94M | -$17.34M |
| YoY Change | 20.77% | 2.16% |
| Interest Expense | $967.0K | $271.0K |
| YoY Change | 256.83% | 3287.5% |
| % of Operating Profit | ||
| Other Income/Expense, Net | $7.670M | $113.0K |
| YoY Change | 6687.61% | -77.93% |
| Pretax Income | -$14.23M | -$17.23M |
| YoY Change | -17.41% | 4.68% |
| Income Tax | ||
| % Of Pretax Income | ||
| Net Earnings | -$14.23M | -$17.23M |
| YoY Change | -17.4% | 4.65% |
| Net Earnings / Revenue | -294.76% | -724.09% |
| Basic Earnings Per Share | ||
| Diluted Earnings Per Share | -$231.8K | -$392.3K |
| COMMON SHARES | ||
| Basic Shares Outstanding | ||
| Diluted Shares Outstanding |
Balance Sheet
| Concept | 2021 Q1 | 2020 Q1 |
|---|---|---|
| SHORT-TERM ASSETS | ||
| Cash & Short-Term Investments | $222.1M | $121.9M |
| YoY Change | 82.2% | 60.61% |
| Cash & Equivalents | $222.1M | $116.9M |
| Short-Term Investments | $0.00 | $5.000M |
| Other Short-Term Assets | $1.900M | $2.200M |
| YoY Change | -13.64% | 15.79% |
| Inventory | ||
| Prepaid Expenses | ||
| Receivables | $2.600M | $1.600M |
| Other Receivables | $0.00 | $0.00 |
| Total Short-Term Assets | $226.7M | $125.7M |
| YoY Change | 80.36% | 61.64% |
| LONG-TERM ASSETS | ||
| Property, Plant & Equipment | $29.10M | $15.76M |
| YoY Change | 84.69% | 304.31% |
| Goodwill | ||
| YoY Change | ||
| Intangibles | ||
| YoY Change | ||
| Long-Term Investments | ||
| YoY Change | ||
| Other Assets | $1.743M | $776.0K |
| YoY Change | 124.61% | -29.65% |
| Total Long-Term Assets | $33.90M | $35.71M |
| YoY Change | -5.06% | 234.79% |
| TOTAL ASSETS | ||
| Total Short-Term Assets | $226.7M | $125.7M |
| Total Long-Term Assets | $33.90M | $35.71M |
| Total Assets | $260.6M | $161.4M |
| YoY Change | 61.46% | 82.52% |
| SHORT-TERM LIABILITIES | ||
| YoY Change | ||
| Accounts Payable | $3.700M | $4.636M |
| YoY Change | -20.19% | 76.14% |
| Accrued Expenses | $10.70M | $8.100M |
| YoY Change | 32.1% | -21.36% |
| Deferred Revenue | ||
| YoY Change | ||
| Short-Term Debt | $0.00 | $0.00 |
| YoY Change | ||
| Long-Term Debt Due | $300.0K | $200.0K |
| YoY Change | 50.0% | 0.0% |
| Total Short-Term Liabilities | $27.40M | $19.80M |
| YoY Change | 38.38% | 32.19% |
| LONG-TERM LIABILITIES | ||
| Long-Term Debt | $39.72M | $20.10M |
| YoY Change | 97.6% | 2412.5% |
| Other Long-Term Liabilities | $43.40M | $44.90M |
| YoY Change | -3.34% | 416.09% |
| Total Long-Term Liabilities | $39.72M | $65.00M |
| YoY Change | -38.9% | 584.21% |
| TOTAL LIABILITIES | ||
| Total Short-Term Liabilities | $27.40M | $19.80M |
| Total Long-Term Liabilities | $39.72M | $65.00M |
| Total Liabilities | $110.7M | $84.90M |
| YoY Change | 30.39% | 247.95% |
| SHAREHOLDERS EQUITY | ||
| Retained Earnings | -$391.2M | |
| YoY Change | ||
| Common Stock | ||
| YoY Change | ||
| Preferred Stock | ||
| YoY Change | ||
| Treasury Stock (at cost) | ||
| YoY Change | ||
| Treasury Stock Shares | ||
| Shareholders Equity | $149.9M | $76.54M |
| YoY Change | ||
| Total Liabilities & Shareholders Equity | $260.6M | $161.4M |
| YoY Change | 61.48% | 82.52% |
Cashflow Statement
| Concept | 2021 Q1 | 2020 Q1 |
|---|---|---|
| OPERATING ACTIVITIES | ||
| Net Income | -$14.23M | -$17.23M |
| YoY Change | -17.4% | 4.65% |
| Depreciation, Depletion And Amortization | $666.0K | $678.0K |
| YoY Change | -1.77% | 31.14% |
| Cash From Operating Activities | -$21.99M | $246.0K |
| YoY Change | -9039.02% | -101.21% |
| INVESTING ACTIVITIES | ||
| Capital Expenditures | $262.0K | $1.797M |
| YoY Change | -85.42% | 204.06% |
| Acquisitions | ||
| YoY Change | ||
| Other Investing Activities | $0.00 | $45.00M |
| YoY Change | -100.0% | -1336.26% |
| Cash From Investing Activities | -$262.0K | $43.20M |
| YoY Change | -100.61% | -1121.59% |
| FINANCING ACTIVITIES | ||
| Cash Dividend Paid | ||
| YoY Change | ||
| Common Stock Issuance & Retirement, Net | $11.94M | |
| YoY Change | ||
| Debt Paid & Issued, Net | ||
| YoY Change | ||
| Cash From Financing Activities | 70.41M | 31.69M |
| YoY Change | 122.16% | -27659.13% |
| NET CHANGE | ||
| Cash From Operating Activities | -21.99M | 246.0K |
| Cash From Investing Activities | -262.0K | 43.20M |
| Cash From Financing Activities | 70.41M | 31.69M |
| Net Change In Cash | 48.16M | 75.14M |
| YoY Change | -35.91% | -404.58% |
| FREE CASH FLOW | ||
| Cash From Operating Activities | -$21.99M | $246.0K |
| Capital Expenditures | $262.0K | $1.797M |
| Free Cash Flow | -$22.25M | -$1.551M |
| YoY Change | 1334.69% | -92.59% |
Facts In Submission
| Frame | Concept Type | Concept / XBRL Key | Value | Unit |
|---|---|---|---|---|
| CY2021Q1 | us-gaap |
Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
|
P8Y11M1D | |
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Finance Lease Weighted Average Remaining Lease Term1
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|
P2Y21D | |
| CY2020 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
|
P7Y2M12D | |
| CY2021Q1 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
|
P6Y9M18D | |
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Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1
|
P5Y10M24D | |
| CY2020Q4 | us-gaap |
Accounts Receivable Net Current
AccountsReceivableNetCurrent
|
7000 | |
| CY2021Q1 | us-gaap |
Other Assets Noncurrent
OtherAssetsNoncurrent
|
1743000 | |
| CY2021Q1 | us-gaap |
Restricted Cash And Cash Equivalents Noncurrent
RestrictedCashAndCashEquivalentsNoncurrent
|
3086000 | |
| CY2021Q1 | us-gaap |
Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
|
14662000 | |
| CY2021Q1 | us-gaap |
Finance Lease Liability Current
FinanceLeaseLiabilityCurrent
|
271000 | |
| CY2020Q1 | us-gaap |
Other Comprehensive Income Availableforsale Securities Adjustment Net Of Tax Portion Attributable To Parent
OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent
|
-21000 | |
| CY2020Q4 | us-gaap |
Liabilities Current
LiabilitiesCurrent
|
28624000 | |
| CY2021Q1 | us-gaap |
Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
|
0.001 | |
| CY2021Q1 | us-gaap |
Preferred Stock Shares Authorized
PreferredStockSharesAuthorized
|
10000000 | |
| CY2021Q1 | us-gaap |
Preferred Stock Shares Issued
PreferredStockSharesIssued
|
0 | |
| CY2021Q1 | us-gaap |
Preferred Stock Shares Outstanding
PreferredStockSharesOutstanding
|
0 | |
| CY2021Q1 | us-gaap |
Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
|
0.001 | |
| CY2021Q1 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
200000000 | |
| CY2021Q1 | us-gaap |
Common Stock Shares Issued
CommonStockSharesIssued
|
61849642 | |
| CY2021Q1 | us-gaap |
Common Stock Shares Outstanding
CommonStockSharesOutstanding
|
61849642 | |
| CY2021Q1 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-391249000 | |
| CY2021Q1 | us-gaap |
Stockholders Equity
StockholdersEquity
|
149880000 | |
| CY2021Q1 | us-gaap |
Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
|
260627000 | |
| CY2021Q1 | us-gaap |
Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
|
4827000 | |
| CY2020Q1 | us-gaap |
Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
|
2379000 | |
| CY2021Q1 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
5739000 | |
| CY2020Q1 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
5149000 | |
| CY2021Q1 | us-gaap |
Investment Income Interest
InvestmentIncomeInterest
|
10000 | |
| CY2020Q1 | us-gaap |
Investment Income Interest
InvestmentIncomeInterest
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384000 | |
| CY2021Q1 | us-gaap |
Interest Expense
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|
967000 | |
| CY2020Q1 | us-gaap |
Interest Expense
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|
271000 | |
| CY2021Q1 | syrs |
Gain Loss On Change In Fair Value Of Warrant Liability
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|
7670000 | |
| CY2020Q1 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.39 | |
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Weighted Average Number Of Share Outstanding Basic And Diluted
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|
43923999 | |
| CY2020Q1 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-17226000 | |
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Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
2459000 | |
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Adjustments To Additional Paid In Capital Warrant Issued
AdjustmentsToAdditionalPaidInCapitalWarrantIssued
|
128000 | |
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Stockholders Equity
StockholdersEquity
|
90553000 | |
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Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
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157000 | |
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Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
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2930000 | |
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Stockholders Equity
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149880000 | |
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Profit Loss
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Profit Loss
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Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
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Depreciation Depletion And Amortization
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Finance Lease Right Of Use Asset Amortization
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Share Based Compensation
ShareBasedCompensation
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2930000 | |
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Share Based Compensation
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Accretion Amortization Of Discounts And Premiums Investments
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Amortization Of Debit Discount And Accretion Of Deferred Debt Costs
AmortizationOfDebitDiscountAndAccretionOfDeferredDebtCosts
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167000 | |
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Amortization Of Debit Discount And Accretion Of Deferred Debt Costs
AmortizationOfDebitDiscountAndAccretionOfDeferredDebtCosts
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40000 | |
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Increase Decrease In Prepaid Expense And Other Current Assets
IncreaseDecreaseInPrepaidExpenseAndOtherCurrentAssets
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-358000 | |
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IncreaseDecreaseInAccountsReceivable
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Increase Decrease In Contract With Customer Asset
IncreaseDecreaseInContractWithCustomerAsset
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298000 | |
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Increase Decrease In Contract With Customer Asset
IncreaseDecreaseInContractWithCustomerAsset
|
1477000 | |
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Increase Decrease In Other Noncurrent Assets
IncreaseDecreaseInOtherNoncurrentAssets
|
27000 | |
| CY2020Q1 | us-gaap |
Increase Decrease In Other Noncurrent Assets
IncreaseDecreaseInOtherNoncurrentAssets
|
286000 | |
| CY2021Q1 | us-gaap |
Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
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Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
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Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
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-1680000 | |
| CY2020Q1 | us-gaap |
Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
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-3357000 | |
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Increase Decrease In Contract With Customer Liability
IncreaseDecreaseInContractWithCustomerLiability
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-2134000 | |
| CY2020Q1 | us-gaap |
Increase Decrease In Contract With Customer Liability
IncreaseDecreaseInContractWithCustomerLiability
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-902000 | |
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Increase Decrease In Proceeds For Tenant Improvement Incentive From Landlord
IncreaseDecreaseInProceedsForTenantImprovementIncentiveFromLandlord
|
586000 | |
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Increase Decrease In Operating Lease Asset And Liabilities
IncreaseDecreaseInOperatingLeaseAssetAndLiabilities
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180000 | |
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Increase Decrease In Operating Lease Asset And Liabilities
IncreaseDecreaseInOperatingLeaseAssetAndLiabilities
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-417000 | |
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NetCashProvidedByUsedInOperatingActivities
|
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Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
246000 | |
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Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
262000 | |
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Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
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1797000 | |
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Proceeds From Sale And Maturity Of Marketable Securities
ProceedsFromSaleAndMaturityOfMarketableSecurities
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45000000 | |
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Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
-262000 | |
| CY2020Q1 | us-gaap |
Net Cash Provided By Used In Investing Activities
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43203000 | |
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Repayments Of Debt And Capital Lease Obligations
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| CY2020Q1 | us-gaap |
Repayments Of Debt And Capital Lease Obligations
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|
58000 | |
| CY2021Q1 | us-gaap |
Proceeds From Issuance Of Shares Under Incentive And Share Based Compensation Plans Including Stock Options
ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions
|
157000 | |
| CY2020Q1 | us-gaap |
Proceeds From Issuance Of Shares Under Incentive And Share Based Compensation Plans Including Stock Options
ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions
|
100000 | |
| CY2020Q1 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
11937000 | |
| CY2020Q1 | us-gaap |
Proceeds From Debt Net Of Issuance Costs
ProceedsFromDebtNetOfIssuanceCosts
|
19714000 | |
| CY2021Q1 | syrs |
Proceeds From Issuance Of Common Stock In Public Offering Net Of Issuance Costs
ProceedsFromIssuanceOfCommonStockInPublicOfferingNetOfIssuanceCosts
|
70353000 | |
| CY2021Q1 | syrs |
Payment Of Issuance Cost Related To Out Of Period Offering And Debt Issuance
PaymentOfIssuanceCostRelatedToOutOfPeriodOfferingAndDebtIssuance
|
36000 | |
| CY2021Q1 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
70410000 | |
| CY2020Q1 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
31693000 | |
| CY2021Q1 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
48158000 | |
| CY2020Q1 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
75142000 | |
| CY2020Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
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|
177070000 | |
| CY2019Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
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|
44817000 | |
| CY2021Q1 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
225228000 | |
| CY2020Q1 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
119959000 | |
| CY2021Q1 | us-gaap |
Interest Paid Net
InterestPaidNet
|
789000 | |
| CY2020Q1 | us-gaap |
Interest Paid Net
InterestPaidNet
|
231000 | |
| CY2020Q1 | us-gaap |
Income Taxes Paid
IncomeTaxesPaid
|
7000 | |
| CY2020Q1 | us-gaap |
Capital Expenditures Incurred But Not Yet Paid
CapitalExpendituresIncurredButNotYetPaid
|
991000 | |
| CY2020Q1 | us-gaap |
Debt Issuance Costs Incurred During Noncash Or Partial Noncash Transaction
DebtIssuanceCostsIncurredDuringNoncashOrPartialNoncashTransaction
|
10000 | |
| CY2021Q1 | syrs |
Offering Cost Incurred But Not Yet Paid
OfferingCostIncurredButNotYetPaid
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26000 | |
| CY2020Q1 | syrs |
Offering Cost Incurred But Not Yet Paid
OfferingCostIncurredButNotYetPaid
|
41000 | |
| CY2021Q1 | us-gaap |
Nature Of Operations
NatureOfOperations
|
<p style="margin-bottom:0pt;margin-top:0pt;text-indent:0%;font-weight:bold;color:#000000;font-size:10pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">1. Nature of Business</p> <p style="margin-bottom:0pt;margin-top:0pt;text-indent:7.42%;font-family:Times New Roman;font-size:11pt;"> </p> <p style="margin-bottom:0pt;margin-top:0pt;text-indent:7.42%;color:#000000;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">Syros Pharmaceuticals, Inc. (the "Company"), a Delaware corporation formed in November 2011, is a biopharmaceutical company seeking to redefine the power of small molecules to control the expression of genes.</p> <p style="margin-bottom:0pt;margin-top:0pt;text-indent:3.71%;font-family:Times New Roman;font-size:11pt;"> </p> <p style="margin-bottom:0pt;margin-top:0pt;text-indent:7.42%;color:#000000;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">The Company is subject to a number of risks similar to those of other early stage companies, including dependence on key individuals; risks inherent in the development and commercialization of medicines to treat human disease; competition from other companies, many of which are larger and better capitalized; risks relating to obtaining and maintaining necessary intellectual property protection; and the need to obtain adequate additional financing to fund the development of its product candidates and discovery activities. If the Company is unable to raise capital when needed or on favorable terms, it would be forced to delay, reduce, eliminate or out-license certain of its research and development programs or future commercialization rights to its product candidates.</p> <p style="margin-bottom:0pt;margin-top:0pt;text-indent:7.42%;font-family:Times New Roman;font-size:11pt;"> </p> <p style="margin-bottom:0pt;margin-top:0pt;text-indent:7.42%;color:#000000;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">On January 22, 2021, the Company issued and sold an aggregate of 5,400,000 shares of its common stock in an underwritten public offering at a public offering price of $14.00 per share, resulting in gross proceeds of $75.6 million before deducting underwriting discounts and commissions and other transaction expenses of approximately $5.1 million. </p> <p style="margin-bottom:0pt;margin-top:0pt;text-indent:7.42%;font-family:Times New Roman;font-size:11pt;"> </p> <p style="margin-bottom:0pt;margin-top:0pt;text-indent:7.42%;color:#000000;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">The Company has incurred significant annual net operating losses in every year since its inception. It expects to continue to incur significant and increasing net operating losses for at least the next several years. The Company’s net losses were $84.0 million, $75.4 million and $62.3 million for the years ended December 31, 2020, 2019 and 2018, respectively. As of March 31, 2021, the Company had an accumulated deficit of $391.2 million. The Company has not generated any revenues from product sales, has not completed the development of any product candidate and may never have a product candidate approved for commercialization. The Company has financed its operations to date primarily through the sale of equity securities, license and collaboration agreements and term debt. The Company has devoted substantially all of its financial resources and efforts to research and development and general and administrative activities to support such research and development. The Company’s net losses may fluctuate significantly from quarter to quarter and year to year. Net losses and negative cash flows have had, and will continue to have, an adverse effect on the Company’s stockholders' equity and working capital. <span style="color:#000000;">The Company believes that its cash and cash equivalents of $222.1 million as of </span>March 31, 2021<span style="color:#000000;"> will be sufficient to allow the Company to fund its current operating plan for a period of at least 12 months past the issuance date of these unaudited interim condensed consolidated financial statements</span>. </p> | |
| CY2020 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-84000000.0 | |
| CY2019 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-75400000 | |
| CY2018 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-62300000 | |
| CY2021Q1 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-391200000 | |
| CY2021Q1 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
222100000 | |
| CY2021Q1 | us-gaap |
Use Of Estimates
UseOfEstimates
|
<p style="margin-bottom:0pt;margin-top:10pt;text-indent:0%;font-weight:bold;color:#000000;font-size:10pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Use of Estimates</p> <p style="margin-bottom:0pt;margin-top:0pt;text-indent:7.42%;font-size:10pt;"> </p> <p style="margin-bottom:0pt;margin-top:0pt;text-indent:7.42%;color:#000000;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">The preparation of financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the reported amounts in the financial statements and accompanying notes. Management considers many factors in selecting appropriate financial accounting policies and in developing the estimates and assumptions that are used in the preparation of the financial statements. Management must apply significant judgment in this process. In addition, other factors may affect estimates, which include, but are not limited to, expected business and operational changes, sensitivity and volatility associated with the assumptions used in developing estimates and whether historical trends are expected to be representative of future trends. Management’s estimation process may yield a range of potentially reasonable estimates and management must select an amount that falls within that range of reasonable estimates. On an ongoing basis, the Company’s management evaluates its estimates, which include, but are not limited to, estimates related to revenue recognition, warrant liability, stock-based compensation expense, accrued expenses and income taxes. Actual results may differ from those estimates or assumptions. The full extent to which the COVID-19 pandemic will directly or indirectly impact the Company’s business, results of operations and financial condition, including expenses, reserves and allowances, clinical trials, research and development costs and employee-related amounts, will depend on future developments that are highly uncertain, including as a result of new information that may emerge concerning COVID-19 and the actions taken to contain it or treat it.</p> | |
| CY2021Q1 | us-gaap |
Number Of Operating Segments
NumberOfOperatingSegments
|
1 | |
| CY2021Q1 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
13564707 | |
| CY2020Q1 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
9291165 | |
| CY2021Q1 | us-gaap |
Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights
ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
|
2117094 | |
| CY2020Q1 | us-gaap |
Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights
ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
|
2118094 | |
| CY2020Q4 | syrs |
Accounts Receivable And Contract Assets
AccountsReceivableAndContractAssets
|
2331000 | |
| CY2021Q1 | syrs |
Accounts Receivable And Contract Assets Additions
AccountsReceivableAndContractAssetsAdditions
|
5019000 | |
| CY2021Q1 | syrs |
Accounts Receivable And Contract Assets Deductions
AccountsReceivableAndContractAssetsDeductions
|
-4728000 | |
| CY2021Q1 | syrs |
Accounts Receivable And Contract Assets
AccountsReceivableAndContractAssets
|
2622000 | |
| CY2020Q4 | us-gaap |
Contract With Customer Liability
ContractWithCustomerLiability
|
22086000 | |
| CY2021Q1 | syrs |
Contract With Customer Liability Additions
ContractWithCustomerLiabilityAdditions
|
71000 | |
| CY2021Q1 | syrs |
Contract With Customer Liability Deductions
ContractWithCustomerLiabilityDeductions
|
-2205000 | |
| CY2021Q1 | us-gaap |
Contract With Customer Liability
ContractWithCustomerLiability
|
19952000 | |
| CY2021Q1 | us-gaap |
Available For Sale Securities Amortized Cost
AvailableForSaleSecuritiesAmortizedCost
|
222142000 | |
| CY2021Q1 | us-gaap |
Available For Sale Securities
AvailableForSaleSecurities
|
222142000 | |
| CY2020Q4 | us-gaap |
Available For Sale Securities Amortized Cost
AvailableForSaleSecuritiesAmortizedCost
|
173984000 | |
| CY2020Q4 | us-gaap |
Available For Sale Securities
AvailableForSaleSecurities
|
173984000 | |
| CY2021Q1 | us-gaap |
Available For Sale Securities Gross Realized Gain Loss Net
AvailableForSaleSecuritiesGrossRealizedGainLossNet
|
0 | |
| CY2020Q1 | us-gaap |
Available For Sale Securities Gross Realized Gain Loss Net
AvailableForSaleSecuritiesGrossRealizedGainLossNet
|
0 | |
| CY2021Q1 | syrs |
Number Of Investments Adjusted For Other Than Temporary Declines In Fair Value
NumberOfInvestmentsAdjustedForOtherThanTemporaryDeclinesInFairValue
|
0 | |
| CY2020Q1 | syrs |
Number Of Investments Adjusted For Other Than Temporary Declines In Fair Value
NumberOfInvestmentsAdjustedForOtherThanTemporaryDeclinesInFairValue
|
0 | |
| CY2021Q1 | us-gaap |
Restricted Cash And Cash Equivalents Noncurrent
RestrictedCashAndCashEquivalentsNoncurrent
|
3100000 | |
| CY2020Q4 | us-gaap |
Restricted Cash And Cash Equivalents Noncurrent
RestrictedCashAndCashEquivalentsNoncurrent
|
3100000 | |
| CY2021Q1 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
222142000 | |
| CY2020Q4 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
173984000 | |
| CY2020Q1 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
116873000 | |
| CY2019Q4 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
41441000 | |
| CY2019Q4 | us-gaap |
Restricted Cash And Cash Equivalents At Carrying Value
RestrictedCashAndCashEquivalentsAtCarryingValue
|
290000 | |
| CY2021Q1 | us-gaap |
Restricted Cash And Cash Equivalents Noncurrent
RestrictedCashAndCashEquivalentsNoncurrent
|
3086000 | |
| CY2020Q4 | us-gaap |
Restricted Cash And Cash Equivalents Noncurrent
RestrictedCashAndCashEquivalentsNoncurrent
|
3086000 | |
| CY2020Q1 | us-gaap |
Restricted Cash And Cash Equivalents Noncurrent
RestrictedCashAndCashEquivalentsNoncurrent
|
3086000 | |
| CY2019Q4 | us-gaap |
Restricted Cash And Cash Equivalents Noncurrent
RestrictedCashAndCashEquivalentsNoncurrent
|
3086000 | |
| CY2021Q1 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
225228000 | |
| CY2020Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
177070000 | |
| CY2020Q1 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
119959000 | |
| CY2019Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
44817000 | |
| CY2021Q1 | us-gaap |
Long Term Debt Maturities Repayments Of Principal In Year Two
LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo
|
16666000 | |
| CY2021Q1 | us-gaap |
Long Term Debt Maturities Repayments Of Principal In Year Three
LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree
|
20000000 | |
| CY2021Q1 | us-gaap |
Long Term Debt Maturities Repayments Of Principal In Year Four
LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour
|
3334000 | |
| CY2021Q1 | us-gaap |
Long Term Debt
LongTermDebt
|
40000000 | |
| CY2021Q1 | us-gaap |
Debt Instrument Unamortized Discount
DebtInstrumentUnamortizedDiscount
|
600000 | |
| CY2021Q1 | us-gaap |
Accumulated Amortization Deferred Finance Costs
AccumulatedAmortizationDeferredFinanceCosts
|
318000 | |
| CY2021Q1 | us-gaap |
Long Term Debt Noncurrent
LongTermDebtNoncurrent
|
39718000 | |
| CY2021Q1 | syrs |
Accrued External Research And Preclinical Development Expenses
AccruedExternalResearchAndPreclinicalDevelopmentExpenses
|
6367000 | |
| CY2020Q4 | syrs |
Accrued External Research And Preclinical Development Expenses
AccruedExternalResearchAndPreclinicalDevelopmentExpenses
|
4702000 | |
| CY2021Q1 | us-gaap |
Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
|
2180000 | |
| CY2020Q4 | us-gaap |
Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
|
5715000 | |
| CY2021Q1 | us-gaap |
Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
|
503000 | |
| CY2020Q4 | us-gaap |
Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
|
602000 | |
| CY2021Q1 | us-gaap |
Accrued Rent Current
AccruedRentCurrent
|
77000 | |
| CY2020Q4 | us-gaap |
Accrued Rent Current
AccruedRentCurrent
|
65000 | |
| CY2021Q1 | syrs |
Accrued Liabilities And Employee Related Liabilities Current
AccruedLiabilitiesAndEmployeeRelatedLiabilitiesCurrent
|
9127000 | |
| CY2020Q4 | syrs |
Accrued Liabilities And Employee Related Liabilities Current
AccruedLiabilitiesAndEmployeeRelatedLiabilitiesCurrent
|
11084000 | |
| CY2019Q1 | us-gaap |
Lessee Finance Lease Term Of Contract1
LesseeFinanceLeaseTermOfContract1
|
P48M | |
| CY2019Q1 | us-gaap |
Finance Lease Liability
FinanceLeaseLiability
|
1000000.0 | |
| CY2019Q1 | us-gaap |
Finance Lease Right Of Use Asset
FinanceLeaseRightOfUseAsset
|
1000000.0 | |
| CY2021Q1 | us-gaap |
Lessee Operating Lease Liability Payments Remainder Of Fiscal Year
LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear
|
2873000 | |
| CY2021Q1 | us-gaap |
Finance Lease Liability Payments Remainder Of Fiscal Year
FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear
|
234000 | |
| CY2021Q1 | us-gaap |
Lessee Operating Lease Liability Payments Due Next Twelve Months
LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
|
3935000 | |
| CY2021Q1 | us-gaap |
Finance Lease Liability Payments Due Next Twelve Months
FinanceLeaseLiabilityPaymentsDueNextTwelveMonths
|
313000 | |
| CY2021Q1 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Two
LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
|
4049000 | |
| CY2021Q1 | us-gaap |
Finance Lease Liability Payments Due Year Two
FinanceLeaseLiabilityPaymentsDueYearTwo
|
66000 | |
| CY2021Q1 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Three
LesseeOperatingLeaseLiabilityPaymentsDueYearThree
|
4166000 | |
| CY2021Q1 | syrs |
Lessee Operating Lease Liability Payments Due Year Four And After Year Four
LesseeOperatingLeaseLiabilityPaymentsDueYearFourAndAfterYearFour
|
23543000 | |
| CY2021Q1 | us-gaap |
Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
|
38566000 | |
| CY2021Q1 | us-gaap |
Finance Lease Liability Payments Due
FinanceLeaseLiabilityPaymentsDue
|
613000 | |
| CY2021Q1 | us-gaap |
Lessee Operating Lease Liability Undiscounted Excess Amount
LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
|
12874000 | |
| CY2021Q1 | us-gaap |
Finance Lease Liability Undiscounted Excess Amount
FinanceLeaseLiabilityUndiscountedExcessAmount
|
56000 | |
| CY2021Q1 | us-gaap |
Operating Lease Liability
OperatingLeaseLiability
|
25692000 | |
| CY2021Q1 | us-gaap |
Finance Lease Liability
FinanceLeaseLiability
|
557000 | |
| CY2021Q1 | us-gaap |
Operating Lease Cost
OperatingLeaseCost
|
772000 | |
| CY2021Q1 | us-gaap |
Finance Lease Right Of Use Asset Amortization
FinanceLeaseRightOfUseAssetAmortization
|
65000 | |
| CY2021Q1 | us-gaap |
Finance Lease Interest Expense
FinanceLeaseInterestExpense
|
14000 | |
| CY2021Q1 | syrs |
Finance Lease Cost
FinanceLeaseCost
|
79000 | |
| CY2021Q1 | us-gaap |
Operating Lease Payments
OperatingLeasePayments
|
951000 | |
| CY2021Q1 | us-gaap |
Finance Lease Principal Payments
FinanceLeasePrincipalPayments
|
78000 | |
| CY2021Q1 | us-gaap |
Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
|
0.0930 | |
| CY2021Q1 | us-gaap |
Finance Lease Weighted Average Discount Rate Percent
FinanceLeaseWeightedAverageDiscountRatePercent
|
0.0947 | |
| CY2019Q2 | syrs |
Number Of Underwriting Agreements
NumberOfUnderwritingAgreements
|
2 | |
| CY2019Q2 | us-gaap |
Proceeds From Issuance Initial Public Offering
ProceedsFromIssuanceInitialPublicOffering
|
70000000.0 | |
| CY2019Q2 | syrs |
Underwriting Discounts And Commissions And Estimated Offering Expenses Payable
UnderwritingDiscountsAndCommissionsAndEstimatedOfferingExpensesPayable
|
5000000.0 | |
| CY2020Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
|
5468605 | |
| CY2020Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
|
8.90 | |
| CY2020Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
|
13124000 | |
| CY2021Q1 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
|
1059600 | |
| CY2021Q1 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
|
11.34 | |
| CY2021Q1 | us-gaap |
Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
|
20134 | |
| CY2021Q1 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
|
7.77 | |
| CY2021Q1 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures And Expirations In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod
|
3670 | |
| CY2021Q1 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures And Expirations In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice
|
9.69 | |
| CY2021Q1 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
|
6504401 | |
| CY2021Q1 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
|
9.30 | |
| CY2021Q1 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
|
3056000 | |
| CY2021Q1 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber
|
3754472 | |
| CY2021Q1 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice
|
9.24 | |
| CY2021Q1 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1
|
2628000 | |
| CY2021Q1 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
100000 | |
| CY2020Q1 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
100000 | |
| CY2021Q1 | us-gaap |
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized
EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized
|
17100000 | |
| CY2021Q1 | us-gaap |
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1
EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1
|
P2Y10M24D | |
| CY2020Q1 | us-gaap |
Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
|
2459000 | |
| CY2021Q1 | us-gaap |
Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
|
2930000 |
