2021 Q4 Form 10-K Financial Statement

#000155837022002373 Filed on February 28, 2022

View on sec.gov

Income Statement

Concept 2021 Q4 2021 Q3 2021
Revenue $14.95M $13.19M $55.31M
YoY Change -20.2% -27.73% -23.03%
Cost Of Revenue
YoY Change
Gross Profit
YoY Change
Gross Profit Margin
Selling, General & Admin $39.11M $21.30M $99.30M
YoY Change 29.93% -22.55% -8.62%
% of Gross Profit
Research & Development $31.23M $43.74M $193.7M
YoY Change -52.11% -35.08% -25.79%
% of Gross Profit
Depreciation & Amortization $1.361M $1.625M $3.500M
YoY Change -3.48% 19.49% 6.06%
% of Gross Profit
Operating Expenses $71.11M $66.81M $313.1M
YoY Change -25.32% -29.58% -15.29%
Operating Profit -$56.17M -$53.62M -$257.8M
YoY Change -26.57% -30.02% -13.42%
Interest Expense $23.98M $11.74M $46.89M
YoY Change 157.87% 1.46% 5.17%
% of Operating Profit
Other Income/Expense, Net -$166.0K $1.109M
YoY Change -113.44% -60.83%
Pretax Income -$32.19M -$35.32M -$199.6M
YoY Change -52.11% -51.99% -30.35%
Income Tax -$151.0K -$7.000K -$200.0K
% Of Pretax Income
Net Earnings -$32.03M -$35.31M -$199.4M
YoY Change -45.18% -52.06% -28.27%
Net Earnings / Revenue -214.33% -267.61% -360.55%
Basic Earnings Per Share -$0.43 -$0.48 -$2.87
Diluted Earnings Per Share -$0.43 -$0.48 -$2.87
COMMON SHARES
Basic Shares Outstanding 73.70M 73.57M 69.46M
Diluted Shares Outstanding 73.57M 69.46M

Balance Sheet

Concept 2021 Q4 2021 Q3 2021
SHORT-TERM ASSETS
Cash & Short-Term Investments $173.5M $216.2M $173.5M
YoY Change -40.79% -39.66% -40.78%
Cash & Equivalents $89.96M $121.4M $89.96M
Short-Term Investments $83.51M $94.79M $83.51M
Other Short-Term Assets $18.81M $23.19M $18.81M
YoY Change -38.74% -25.45% -38.74%
Inventory
Prepaid Expenses
Receivables $14.07M $14.00M $14.07M
Other Receivables $43.53M $43.77M $43.53M
Total Short-Term Assets $249.9M $297.2M $249.9M
YoY Change -36.47% -34.07% -36.47%
LONG-TERM ASSETS
Property, Plant & Equipment $13.66M $16.00M $53.35M
YoY Change -16.84% 3.71% -10.64%
Goodwill
YoY Change
Intangibles
YoY Change
Long-Term Investments $67.54M $45.09M $67.54M
YoY Change 429.7% 427.63%
Other Assets $3.228M $3.297M $4.065M
YoY Change 31.7% 307.04% 23.18%
Total Long-Term Assets $124.9M $105.9M $124.9M
YoY Change 65.02% 72.36% 64.84%
TOTAL ASSETS
Total Short-Term Assets $249.9M $297.2M $249.9M
Total Long-Term Assets $124.9M $105.9M $124.9M
Total Assets $374.8M $403.1M $374.8M
YoY Change -20.09% -21.3% -20.1%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable $3.098M $8.900M $3.098M
YoY Change -54.27% 38.16% -54.44%
Accrued Expenses $38.45M $41.75M $38.45M
YoY Change -55.24% -47.55% -55.24%
Deferred Revenue $98.00K $2.902M
YoY Change -99.15% -84.06%
Short-Term Debt $0.00 $0.00 $0.00
YoY Change
Long-Term Debt Due $16.94M $12.53M $16.94M
YoY Change -12.23% -12.23%
Total Short-Term Liabilities $58.59M $66.08M $58.59M
YoY Change -52.59% -36.62% -52.6%
LONG-TERM LIABILITIES
Long-Term Debt $599.4M $603.3M $599.4M
YoY Change -0.07% -1.29% -0.07%
Other Long-Term Liabilities $2.420M $2.609M $55.41M
YoY Change 32.02% -73.11% 12.17%
Total Long-Term Liabilities $2.420M $2.609M $654.8M
YoY Change 32.02% -73.11% 0.86%
TOTAL LIABILITIES
Total Short-Term Liabilities $58.59M $66.08M $58.59M
Total Long-Term Liabilities $2.420M $2.609M $654.8M
Total Liabilities $61.01M $68.69M $713.4M
YoY Change -51.35% -39.73% -7.69%
SHAREHOLDERS EQUITY
Retained Earnings -$1.726B -$1.694B
YoY Change 13.06% 15.38%
Common Stock $1.000K $1.000K
YoY Change 0.0% 0.0%
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity -$338.6M -$323.6M -$338.6M
YoY Change
Total Liabilities & Shareholders Equity $374.8M $403.1M $374.8M
YoY Change -20.09% -21.3% -20.1%

Cashflow Statement

Concept 2021 Q4 2021 Q3 2021
OPERATING ACTIVITIES
Net Income -$32.03M -$35.31M -$199.4M
YoY Change -45.18% -52.06% -28.27%
Depreciation, Depletion And Amortization $1.361M $1.625M $3.500M
YoY Change -3.48% 19.49% 6.06%
Cash From Operating Activities -$42.43M -$45.45M -$207.9M
YoY Change -34.64% -41.0% -16.99%
INVESTING ACTIVITIES
Capital Expenditures -$444.0K -$1.039M -$3.406M
YoY Change -64.48% -49.32% -48.55%
Acquisitions
YoY Change
Other Investing Activities $11.27M -$34.75M $127.9M
YoY Change -78.99% -150.68% 637.6%
Cash From Investing Activities $10.82M -$35.79M $124.5M
YoY Change -79.33% -153.79% 1061.22%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net $108.2M
YoY Change -22.68%
Debt Paid & Issued, Net
YoY Change
Cash From Financing Activities 149.0K -2.286M 91.86M
YoY Change -80.13% 135.67% -65.08%
NET CHANGE
Cash From Operating Activities -42.43M -45.45M -207.9M
Cash From Investing Activities 10.82M -35.79M 124.5M
Cash From Financing Activities 149.0K -2.286M 91.86M
Net Change In Cash -31.46M -83.53M 8.496M
YoY Change 166.62% 628.84% -63.7%
FREE CASH FLOW
Cash From Operating Activities -$42.43M -$45.45M -$207.9M
Capital Expenditures -$444.0K -$1.039M -$3.406M
Free Cash Flow -$41.99M -$44.41M -$204.5M
YoY Change -34.05% -40.77% -16.13%

Facts In Submission

Frame Concept Type Concept / XBRL Key Value Unit
CY2021Q4 us-gaap Commitments And Contingencies
CommitmentsAndContingencies
CY2020Q4 us-gaap Commitments And Contingencies
CommitmentsAndContingencies
CY2021 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
69461000
CY2020 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
62345000
CY2019 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
55610000
CY2020Q4 us-gaap Operating Lease Liability Current Statement Of Financial Position Extensible List
OperatingLeaseLiabilityCurrentStatementOfFinancialPositionExtensibleList
http://fasb.org/us-gaap/2021-01-31#OperatingLeaseLiabilityCurrent
CY2020Q4 us-gaap Operating Lease Liability Noncurrent Statement Of Financial Position Extensible List
OperatingLeaseLiabilityNoncurrentStatementOfFinancialPositionExtensibleList
http://fasb.org/us-gaap/2021-01-31#OperatingLeaseLiabilityNoncurrent
CY2021 dei Entity Central Index Key
EntityCentralIndexKey
0001583107
CY2021 dei Document Fiscal Year Focus
DocumentFiscalYearFocus
2021
CY2021 dei Document Fiscal Period Focus
DocumentFiscalPeriodFocus
FY
CY2021 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
69461000
CY2020 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
62345000
CY2019 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
55610000
CY2020Q4 us-gaap Fair Value Assets Level2 To Level1 Transfers Amount
FairValueAssetsLevel2ToLevel1TransfersAmount
0
CY2021Q4 us-gaap Fair Value Assets Level2 To Level1 Transfers Amount
FairValueAssetsLevel2ToLevel1TransfersAmount
0
CY2020Q4 us-gaap Preferred Stock Shares Issued
PreferredStockSharesIssued
0
CY2021Q4 us-gaap Preferred Stock Shares Issued
PreferredStockSharesIssued
0
CY2021Q4 us-gaap Preferred Stock Shares Outstanding
PreferredStockSharesOutstanding
0
CY2020Q4 us-gaap Preferred Stock Shares Outstanding
PreferredStockSharesOutstanding
0
CY2021Q4 us-gaap Preferred Stock Value
PreferredStockValue
CY2020Q4 us-gaap Preferred Stock Value
PreferredStockValue
CY2020Q4 us-gaap Common Stock Shares Issued
CommonStockSharesIssued
64328000
CY2021Q4 us-gaap Common Stock Shares Outstanding
CommonStockSharesOutstanding
74435000
CY2021 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-2.87
CY2020 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-4.46
CY2019 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-4.25
CY2021 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-2.87
CY2020 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-4.46
CY2019 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-4.25
CY2021 us-gaap Lessee Operating Lease Existence Of Option To Extend
LesseeOperatingLeaseExistenceOfOptionToExtend
true
CY2019Q4 us-gaap Operating Lease Liability Current Statement Of Financial Position Extensible List
OperatingLeaseLiabilityCurrentStatementOfFinancialPositionExtensibleList
http://fasb.org/us-gaap/2021-01-31#OperatingLeaseLiabilityCurrent
CY2019Q4 us-gaap Operating Lease Liability Noncurrent Statement Of Financial Position Extensible List
OperatingLeaseLiabilityNoncurrentStatementOfFinancialPositionExtensibleList
http://fasb.org/us-gaap/2021-01-31#OperatingLeaseLiabilityNoncurrent
CY2021Q1 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-1.24
CY2021Q2 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.80
CY2021Q3 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.48
CY2021Q4 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.43
CY2020Q1 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-1.40
CY2020Q2 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-1.00
CY2020Q3 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-1.16
CY2020Q4 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.92
CY2021 dei Amendment Flag
AmendmentFlag
false
CY2021 dei Document Type
DocumentType
10-K
CY2021 dei Document Annual Report
DocumentAnnualReport
true
CY2021 dei Document Period End Date
DocumentPeriodEndDate
2021-12-31
CY2021 dei Current Fiscal Year End Date
CurrentFiscalYearEndDate
--12-31
CY2021 dei Document Transition Report
DocumentTransitionReport
false
CY2021 dei Entity File Number
EntityFileNumber
001-36033
CY2021 dei Entity Registrant Name
EntityRegistrantName
THERAVANCE BIOPHARMA, INC.
CY2021 dei Entity Incorporation State Country Code
EntityIncorporationStateCountryCode
KY
CY2021 dei Entity Tax Identification Number
EntityTaxIdentificationNumber
98-1226628
CY2021 dei Entity Address Address Line1
EntityAddressAddressLine1
P.O. Box 309
CY2021 dei Entity Address Address Line2
EntityAddressAddressLine2
Ugland House, South Church Street
CY2021 dei Entity Address City Or Town
EntityAddressCityOrTown
George Town, Grand Cayman
CY2021 dei Entity Address Country
EntityAddressCountry
KY
CY2021 dei Entity Address Postal Zip Code
EntityAddressPostalZipCode
KY1-1104
CY2021 dei City Area Code
CityAreaCode
650
CY2021 dei Local Phone Number
LocalPhoneNumber
808-6000
CY2021 dei Security12b Title
Security12bTitle
Ordinary Share $0.00001 Par Value
CY2021 dei Trading Symbol
TradingSymbol
TBPH
CY2021 dei Security Exchange Name
SecurityExchangeName
NASDAQ
CY2021 dei Entity Well Known Seasoned Issuer
EntityWellKnownSeasonedIssuer
Yes
CY2021 dei Entity Voluntary Filers
EntityVoluntaryFilers
No
CY2021 dei Entity Current Reporting Status
EntityCurrentReportingStatus
Yes
CY2020Q4 us-gaap Other Assets Noncurrent
OtherAssetsNoncurrent
2451000
CY2021 dei Entity Interactive Data Current
EntityInteractiveDataCurrent
Yes
CY2021 dei Entity Filer Category
EntityFilerCategory
Large Accelerated Filer
CY2021 dei Entity Small Business
EntitySmallBusiness
false
CY2021 dei Entity Emerging Growth Company
EntityEmergingGrowthCompany
false
CY2021 dei Icfr Auditor Attestation Flag
IcfrAuditorAttestationFlag
true
CY2021 dei Entity Shell Company
EntityShellCompany
false
CY2021Q2 dei Entity Public Float
EntityPublicFloat
882100000
CY2022Q1 dei Entity Common Stock Shares Outstanding
EntityCommonStockSharesOutstanding
74696687
CY2021 dei Auditor Firm
AuditorFirmId
42
CY2021Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
89959000
CY2020Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
81467000
CY2021Q4 us-gaap Available For Sale Securities Debt Securities Current
AvailableForSaleSecuritiesDebtSecuritiesCurrent
83506000
CY2020Q4 us-gaap Available For Sale Securities Debt Securities Current
AvailableForSaleSecuritiesDebtSecuritiesCurrent
211474000
CY2021Q4 tbph Receivables From Collaboration Partners
ReceivablesFromCollaborationPartners
14065000
CY2020Q4 tbph Receivables From Collaboration Partners
ReceivablesFromCollaborationPartners
15868000
CY2021Q4 us-gaap Due From Related Parties Current
DueFromRelatedPartiesCurrent
43534000
CY2020Q4 us-gaap Due From Related Parties Current
DueFromRelatedPartiesCurrent
53799000
CY2021Q4 tbph Prepaid Clinical And Development Services
PrepaidClinicalAndDevelopmentServices
10245000
CY2020Q4 tbph Prepaid Clinical And Development Services
PrepaidClinicalAndDevelopmentServices
20374000
CY2021Q4 us-gaap Other Prepaid Expense Current
OtherPrepaidExpenseCurrent
8561000
CY2020Q4 us-gaap Other Prepaid Expense Current
OtherPrepaidExpenseCurrent
10359000
CY2021Q4 us-gaap Assets Current
AssetsCurrent
249870000
CY2020Q4 us-gaap Assets Current
AssetsCurrent
393341000
CY2021Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
13657000
CY2020Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
16422000
CY2021Q4 us-gaap Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
39690000
CY2020Q4 us-gaap Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
43260000
CY2021Q4 us-gaap Equity Method Investments
EquityMethodInvestments
67537000
CY2020Q4 us-gaap Equity Method Investments
EquityMethodInvestments
12750000
CY2021Q4 us-gaap Restricted Cash Noncurrent
RestrictedCashNoncurrent
837000
CY2020Q4 us-gaap Restricted Cash Noncurrent
RestrictedCashNoncurrent
833000
CY2021Q4 us-gaap Other Assets Noncurrent
OtherAssetsNoncurrent
3228000
CY2021Q4 us-gaap Assets
Assets
374819000
CY2020Q4 us-gaap Assets
Assets
469057000
CY2021Q4 us-gaap Accounts Payable Current
AccountsPayableCurrent
3098000
CY2020Q4 us-gaap Accounts Payable Current
AccountsPayableCurrent
6775000
CY2021Q4 us-gaap Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
12796000
CY2020Q4 us-gaap Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
35238000
CY2021Q4 tbph Accrued Clinical And Development Expenses Current
AccruedClinicalAndDevelopmentExpensesCurrent
17010000
CY2020Q4 tbph Accrued Clinical And Development Expenses Current
AccruedClinicalAndDevelopmentExpensesCurrent
28799000
CY2021Q4 tbph Accrued General And Administrative Expenses
AccruedGeneralAndAdministrativeExpenses
2898000
CY2020Q4 tbph Accrued General And Administrative Expenses
AccruedGeneralAndAdministrativeExpenses
6048000
CY2021Q4 us-gaap Interest Payable Current
InterestPayableCurrent
3940000
CY2020Q4 us-gaap Interest Payable Current
InterestPayableCurrent
3974000
CY2021Q4 tbph Non Recourse Debt Due2035 Current
NonRecourseDebtDue2035Current
16940000
CY2020Q4 tbph Non Recourse Debt Due2035 Current
NonRecourseDebtDue2035Current
19334000
CY2021Q4 us-gaap Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
503000
CY2020Q4 us-gaap Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
9867000
CY2021Q4 us-gaap Contract With Customer Liability Current
ContractWithCustomerLiabilityCurrent
98000
CY2020Q4 us-gaap Contract With Customer Liability Current
ContractWithCustomerLiabilityCurrent
11523000
CY2021Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
1304000
CY2020Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
2013000
CY2021Q4 us-gaap Liabilities Current
LiabilitiesCurrent
58587000
CY2020Q4 us-gaap Liabilities Current
LiabilitiesCurrent
123571000
CY2021Q4 us-gaap Convertible Long Term Notes Payable
ConvertibleLongTermNotesPayable
228035000
CY2020Q4 us-gaap Convertible Long Term Notes Payable
ConvertibleLongTermNotesPayable
226963000
CY2021Q4 tbph Non Recourse Debt Due2035 Noncurrent
NonRecourseDebtDue2035Noncurrent
371359000
CY2020Q4 tbph Non Recourse Debt Due2035 Noncurrent
NonRecourseDebtDue2035Noncurrent
372873000
CY2021Q4 us-gaap Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
52681000
CY2020Q4 us-gaap Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
47220000
CY2021Q4 us-gaap Contract With Customer Liability Noncurrent
ContractWithCustomerLiabilityNoncurrent
310000
CY2020Q4 us-gaap Contract With Customer Liability Noncurrent
ContractWithCustomerLiabilityNoncurrent
348000
CY2021Q4 us-gaap Other Liabilities Noncurrent
OtherLiabilitiesNoncurrent
2420000
CY2020Q4 us-gaap Additional Paid In Capital
AdditionalPaidInCapital
1222818000
CY2020Q4 us-gaap Accumulated Other Comprehensive Income Loss Net Of Tax
AccumulatedOtherComprehensiveIncomeLossNetOfTax
47000
CY2021Q4 us-gaap Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
-1726043000
CY2020Q4 us-gaap Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
-1526617000
CY2021Q4 us-gaap Stockholders Equity
StockholdersEquity
-338573000
CY2020Q4 us-gaap Stockholders Equity
StockholdersEquity
-303751000
CY2021Q4 us-gaap Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
374819000
CY2020Q4 us-gaap Other Liabilities Noncurrent
OtherLiabilitiesNoncurrent
1833000
CY2020Q4 us-gaap Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
0.00001
CY2021Q4 us-gaap Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
0.00001
CY2020Q4 us-gaap Preferred Stock Shares Authorized
PreferredStockSharesAuthorized
230000
CY2021Q4 us-gaap Preferred Stock Shares Authorized
PreferredStockSharesAuthorized
230000
CY2020Q4 us-gaap Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
0.00001
CY2021Q4 us-gaap Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
0.00001
CY2020Q4 us-gaap Common Stock Shares Authorized
CommonStockSharesAuthorized
200000000
CY2021Q4 us-gaap Common Stock Shares Authorized
CommonStockSharesAuthorized
200000000
CY2021Q4 us-gaap Common Stock Shares Issued
CommonStockSharesIssued
74435000
CY2020Q4 us-gaap Common Stock Shares Outstanding
CommonStockSharesOutstanding
64328000
CY2021Q4 us-gaap Common Stock Value
CommonStockValue
1000
CY2020Q4 us-gaap Common Stock Value
CommonStockValue
1000
CY2021Q4 us-gaap Additional Paid In Capital
AdditionalPaidInCapital
1387469000
CY2020Q4 us-gaap Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
469057000
CY2021 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
55311000
CY2020 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
71857000
CY2019 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
73414000
CY2021 us-gaap Research And Development Expense
ResearchAndDevelopmentExpense
193657000
CY2020 us-gaap Research And Development Expense
ResearchAndDevelopmentExpense
260953000
CY2019 us-gaap Research And Development Expense
ResearchAndDevelopmentExpense
219248000
CY2021 us-gaap Selling General And Administrative Expense
SellingGeneralAndAdministrativeExpense
99296000
CY2020 us-gaap Selling General And Administrative Expense
SellingGeneralAndAdministrativeExpense
108661000
CY2019 us-gaap Selling General And Administrative Expense
SellingGeneralAndAdministrativeExpense
106081000
CY2021 us-gaap Restructuring Charges
RestructuringCharges
20142000
CY2021 us-gaap Operating Expenses
OperatingExpenses
313095000
CY2020 us-gaap Operating Expenses
OperatingExpenses
369614000
CY2019 us-gaap Operating Expenses
OperatingExpenses
325329000
CY2021 us-gaap Operating Income Loss
OperatingIncomeLoss
-257784000
CY2020 us-gaap Operating Income Loss
OperatingIncomeLoss
-297757000
CY2019 us-gaap Operating Income Loss
OperatingIncomeLoss
-251915000
CY2021 us-gaap Income Loss From Equity Method Investments
IncomeLossFromEquityMethodInvestments
103987000
CY2020 us-gaap Income Loss From Equity Method Investments
IncomeLossFromEquityMethodInvestments
68438000
CY2019 us-gaap Income Loss From Equity Method Investments
IncomeLossFromEquityMethodInvestments
33705000
CY2021 us-gaap Interest Expense
InterestExpense
46889000
CY2020 us-gaap Interest Expense
InterestExpense
44585000
CY2019 us-gaap Interest Expense
InterestExpense
31862000
CY2020 us-gaap Gains Losses On Extinguishment Of Debt
GainsLossesOnExtinguishmentOfDebt
-15464000
CY2021 us-gaap Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
1109000
CY2020 us-gaap Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
2831000
CY2019 us-gaap Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
8395000
CY2021 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-199577000
CY2020 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-286537000
CY2019 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-241677000
CY2021 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
-151000
CY2020 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
-8520000
CY2019 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
-5222000
CY2021 us-gaap Net Income Loss
NetIncomeLoss
-199426000
CY2020 us-gaap Net Income Loss
NetIncomeLoss
-278017000
CY2019 us-gaap Net Income Loss
NetIncomeLoss
-236455000
CY2021 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-2.87
CY2020 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-4.46
CY2019 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-4.25
CY2021 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
69461000
CY2020 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
62345000
CY2019 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
55610000
CY2021 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
62061000
CY2020 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
62976000
CY2019 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
60450000
CY2021 us-gaap Net Income Loss
NetIncomeLoss
-199426000
CY2020 us-gaap Net Income Loss
NetIncomeLoss
-278017000
CY2019 us-gaap Net Income Loss
NetIncomeLoss
-236455000
CY2021 us-gaap Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
-47000
CY2020 us-gaap Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
-98000
CY2019 us-gaap Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
311000
CY2021 us-gaap Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
-199473000
CY2020 us-gaap Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
-278115000
CY2019 us-gaap Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
-236144000
CY2018Q4 us-gaap Stockholders Equity
StockholdersEquity
-51589000
CY2019 us-gaap Stock Issued During Period Value Employee Stock Purchase Plan
StockIssuedDuringPeriodValueEmployeeStockPurchasePlan
3474000
CY2019 us-gaap Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
60450000
CY2019 us-gaap Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
3142000
CY2019 us-gaap Adjustments Related To Tax Withholding For Share Based Compensation
AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation
3173000
CY2019 us-gaap Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
311000
CY2019 us-gaap Net Income Loss
NetIncomeLoss
-236455000
CY2019Q4 us-gaap Stockholders Equity
StockholdersEquity
-223840000
CY2019Q4 us-gaap Stockholders Equity
StockholdersEquity
-223840000
CY2020 us-gaap Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
139915000
CY2020 us-gaap Stock Issued During Period Value Employee Stock Purchase Plan
StockIssuedDuringPeriodValueEmployeeStockPurchasePlan
3701000
CY2020 us-gaap Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
62976000
CY2020 us-gaap Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
1361000
CY2020 us-gaap Adjustments Related To Tax Withholding For Share Based Compensation
AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation
9749000
CY2020 us-gaap Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
-98000
CY2020 us-gaap Net Income Loss
NetIncomeLoss
-278017000
CY2020Q4 us-gaap Stockholders Equity
StockholdersEquity
-303751000
CY2020Q4 us-gaap Stockholders Equity
StockholdersEquity
-303751000
CY2021 us-gaap Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
108180000
CY2021 us-gaap Stock Issued During Period Value Employee Stock Purchase Plan
StockIssuedDuringPeriodValueEmployeeStockPurchasePlan
3466000
CY2021 us-gaap Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
62061000
CY2021 us-gaap Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
5000
CY2021 us-gaap Adjustments Related To Tax Withholding For Share Based Compensation
AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation
9061000
CY2021 us-gaap Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
-47000
CY2021 us-gaap Net Income Loss
NetIncomeLoss
-199426000
CY2021Q4 us-gaap Stockholders Equity
StockholdersEquity
-338573000
CY2021 us-gaap Net Income Loss
NetIncomeLoss
-199426000
CY2020 us-gaap Net Income Loss
NetIncomeLoss
-278017000
CY2019 us-gaap Net Income Loss
NetIncomeLoss
-236455000
CY2021 us-gaap Other Depreciation And Amortization
OtherDepreciationAndAmortization
5912000
CY2020 us-gaap Other Depreciation And Amortization
OtherDepreciationAndAmortization
6798000
CY2019 us-gaap Other Depreciation And Amortization
OtherDepreciationAndAmortization
6441000
CY2021 tbph Amortization And Accretion Income
AmortizationAndAccretionIncome
-10000
CY2020 tbph Increase Decrease In Receivables From Collaboration Partners
IncreaseDecreaseInReceivablesFromCollaborationPartners
-6128000
CY2019 tbph Increase Decrease In Receivables From Collaboration Partners
IncreaseDecreaseInReceivablesFromCollaborationPartners
11943000
CY2021 tbph Increase Decrease In Prepaid Clinical And Development Services
IncreaseDecreaseInPrepaidClinicalAndDevelopmentServices
-10129000
CY2020 tbph Increase Decrease In Prepaid Clinical And Development Services
IncreaseDecreaseInPrepaidClinicalAndDevelopmentServices
17638000
CY2019 tbph Increase Decrease In Prepaid Clinical And Development Services
IncreaseDecreaseInPrepaidClinicalAndDevelopmentServices
561000
CY2021 us-gaap Increase Decrease In Prepaid Expenses Other
IncreaseDecreaseInPrepaidExpensesOther
-2867000
CY2020 us-gaap Increase Decrease In Prepaid Expenses Other
IncreaseDecreaseInPrepaidExpensesOther
2327000
CY2020 tbph Amortization And Accretion Income
AmortizationAndAccretionIncome
1079000
CY2019 tbph Amortization And Accretion Income
AmortizationAndAccretionIncome
3451000
CY2021 us-gaap Share Based Compensation
ShareBasedCompensation
62061000
CY2020 us-gaap Share Based Compensation
ShareBasedCompensation
62976000
CY2019 us-gaap Share Based Compensation
ShareBasedCompensation
60450000
CY2021 us-gaap Gain Loss On Sale Of Property Plant Equipment
GainLossOnSaleOfPropertyPlantEquipment
-39000
CY2021 us-gaap Finance Lease Right Of Use Asset Amortization
FinanceLeaseRightOfUseAssetAmortization
3786000
CY2020 us-gaap Finance Lease Right Of Use Asset Amortization
FinanceLeaseRightOfUseAssetAmortization
3344000
CY2019 us-gaap Finance Lease Right Of Use Asset Amortization
FinanceLeaseRightOfUseAssetAmortization
3224000
CY2021 tbph Gain Loss On Modification Of Lease
GainLossOnModificationOfLease
1863000
CY2021 tbph Equity Method Investments Undistributed Earnings
EquityMethodInvestmentsUndistributedEarnings
44516000
CY2020 tbph Equity Method Investments Undistributed Earnings
EquityMethodInvestmentsUndistributedEarnings
37975000
CY2019 tbph Equity Method Investments Undistributed Earnings
EquityMethodInvestmentsUndistributedEarnings
23152000
CY2021 tbph Interest Shortfall On2035 Notes
InterestShortfallOn2035Notes
5713000
CY2020 tbph Interest Shortfall On2035 Notes
InterestShortfallOn2035Notes
17643000
CY2020 us-gaap Gains Losses On Extinguishment Of Debt
GainsLossesOnExtinguishmentOfDebt
-15464000
CY2021 us-gaap Other Noncash Income Expense
OtherNoncashIncomeExpense
-10000
CY2020 us-gaap Other Noncash Income Expense
OtherNoncashIncomeExpense
95000
CY2019 us-gaap Other Noncash Income Expense
OtherNoncashIncomeExpense
-146000
CY2019 us-gaap Increase Decrease In Accounts Receivable
IncreaseDecreaseInAccountsReceivable
-620000
CY2021 tbph Increase Decrease In Receivables From Collaboration Partners
IncreaseDecreaseInReceivablesFromCollaborationPartners
-1803000
CY2019 us-gaap Increase Decrease In Prepaid Expenses Other
IncreaseDecreaseInPrepaidExpensesOther
73000
CY2020 us-gaap Increase Decrease In Income Taxes Receivable
IncreaseDecreaseInIncomeTaxesReceivable
258000
CY2019 us-gaap Increase Decrease In Income Taxes Receivable
IncreaseDecreaseInIncomeTaxesReceivable
3700000
CY2021 us-gaap Increase Decrease In Other Operating Assets
IncreaseDecreaseInOtherOperatingAssets
972000
CY2020 us-gaap Increase Decrease In Other Operating Assets
IncreaseDecreaseInOtherOperatingAssets
852000
CY2019 us-gaap Increase Decrease In Other Operating Assets
IncreaseDecreaseInOtherOperatingAssets
358000
CY2021 us-gaap Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
-3534000
CY2020 us-gaap Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
3658000
CY2019 us-gaap Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
-4274000
CY2021 us-gaap Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
-37225000
CY2020 us-gaap Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
5983000
CY2019 us-gaap Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
10626000
CY2021 us-gaap Increase Decrease In Interest Payable Net
IncreaseDecreaseInInterestPayableNet
-34000
CY2020 us-gaap Increase Decrease In Interest Payable Net
IncreaseDecreaseInInterestPayableNet
-1685000
CY2019 us-gaap Increase Decrease In Interest Payable Net
IncreaseDecreaseInInterestPayableNet
2573000
CY2021 us-gaap Increase Decrease In Contract With Customer Liability
IncreaseDecreaseInContractWithCustomerLiability
-11463000
CY2020 us-gaap Increase Decrease In Contract With Customer Liability
IncreaseDecreaseInContractWithCustomerLiability
-26465000
CY2019 us-gaap Increase Decrease In Contract With Customer Liability
IncreaseDecreaseInContractWithCustomerLiability
-31245000
CY2021 us-gaap Increase Decrease In Operating Lease Liability
IncreaseDecreaseInOperatingLeaseLiability
-1742000
CY2020 us-gaap Increase Decrease In Operating Lease Liability
IncreaseDecreaseInOperatingLeaseLiability
1600000
CY2019 us-gaap Payments To Acquire Available For Sale Securities Debt
PaymentsToAcquireAvailableForSaleSecuritiesDebt
423898000
CY2021 us-gaap Proceeds From Sale And Maturity Of Available For Sale Securities
ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities
286199000
CY2020 us-gaap Proceeds From Sale And Maturity Of Available For Sale Securities
ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities
399318000
CY2020 us-gaap Payments Of Debt Issuance Costs
PaymentsOfDebtIssuanceCosts
5326000
CY2021 us-gaap Payments To Acquire Available For Sale Securities Debt
PaymentsToAcquireAvailableForSaleSecuritiesDebt
158305000
CY2020 us-gaap Payments To Acquire Available For Sale Securities Debt
PaymentsToAcquireAvailableForSaleSecuritiesDebt
401987000
CY2020 us-gaap Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
139915000
CY2020 us-gaap Proceeds From Issuance Of Long Term Debt
ProceedsFromIssuanceOfLongTermDebt
380000000
CY2019 us-gaap Increase Decrease In Operating Lease Liability
IncreaseDecreaseInOperatingLeaseLiability
-2317000
CY2021 us-gaap Increase Decrease In Other Noncurrent Liabilities
IncreaseDecreaseInOtherNoncurrentLiabilities
587000
CY2020 us-gaap Increase Decrease In Other Noncurrent Liabilities
IncreaseDecreaseInOtherNoncurrentLiabilities
-7606000
CY2019 us-gaap Increase Decrease In Other Noncurrent Liabilities
IncreaseDecreaseInOtherNoncurrentLiabilities
-4748000
CY2021 us-gaap Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
-207858000
CY2020 us-gaap Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
-250403000
CY2019 us-gaap Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
-238197000
CY2021 us-gaap Payments To Acquire Productive Assets
PaymentsToAcquireProductiveAssets
3406000
CY2020 us-gaap Payments To Acquire Productive Assets
PaymentsToAcquireProductiveAssets
6616000
CY2019 us-gaap Payments To Acquire Productive Assets
PaymentsToAcquireProductiveAssets
3176000
CY2019 us-gaap Proceeds From Sale And Maturity Of Available For Sale Securities
ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities
339018000
CY2020 us-gaap Proceeds From Sale And Maturity Of Marketable Securities
ProceedsFromSaleAndMaturityOfMarketableSecurities
19942000
CY2021 us-gaap Proceeds From Sale Of Property Plant And Equipment
ProceedsFromSaleOfPropertyPlantAndEquipment
6000
CY2020 us-gaap Proceeds From Sale Of Property Plant And Equipment
ProceedsFromSaleOfPropertyPlantAndEquipment
64000
CY2019 us-gaap Proceeds From Sale Of Property Plant And Equipment
ProceedsFromSaleOfPropertyPlantAndEquipment
5000
CY2019 us-gaap Proceeds From Divestiture Of Businesses Net Of Cash Divested
ProceedsFromDivestitureOfBusinessesNetOfCashDivested
5000000
CY2021 us-gaap Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
124494000
CY2020 us-gaap Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
10721000
CY2019 us-gaap Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
-83051000
CY2021 us-gaap Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
108180000
CY2021 us-gaap Repayments Of Notes Payable
RepaymentsOfNotesPayable
10730000
CY2020 us-gaap Payments Of Loan Costs
PaymentsOfLoanCosts
11470000
CY2020 us-gaap Repayments Of Notes Payable
RepaymentsOfNotesPayable
235347000
CY2019 us-gaap Repayments Of Notes Payable
RepaymentsOfNotesPayable
2152000
CY2021 us-gaap Proceeds From Stock Plans
ProceedsFromStockPlans
3466000
CY2020 us-gaap Proceeds From Stock Plans
ProceedsFromStockPlans
3701000
CY2019 us-gaap Proceeds From Stock Plans
ProceedsFromStockPlans
3474000
CY2021 us-gaap Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
5000
CY2020 us-gaap Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
1361000
CY2019 us-gaap Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
3142000
CY2021 us-gaap Payments Related To Tax Withholding For Share Based Compensation
PaymentsRelatedToTaxWithholdingForShareBasedCompensation
9061000
CY2020 us-gaap Payments Related To Tax Withholding For Share Based Compensation
PaymentsRelatedToTaxWithholdingForShareBasedCompensation
9749000
CY2019 us-gaap Payments Related To Tax Withholding For Share Based Compensation
PaymentsRelatedToTaxWithholdingForShareBasedCompensation
3173000
CY2021 us-gaap Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
91860000
CY2020 us-gaap Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
263085000
CY2019 us-gaap Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
1291000
CY2021 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
8496000
CY2020 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
23403000
CY2019 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
-319957000
CY2020Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
82300000
CY2019 us-gaap Interest Paid Net
InterestPaidNet
26178000
CY2021 us-gaap Income Taxes Paid Net
IncomeTaxesPaidNet
-4089000
CY2020 us-gaap Income Taxes Paid Net
IncomeTaxesPaidNet
14000
CY2019 us-gaap Income Taxes Paid Net
IncomeTaxesPaidNet
22000
CY2019 us-gaap Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
49847000
CY2019Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
58897000
CY2018Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
378854000
CY2021Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
90796000
CY2020Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
82300000
CY2019Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
58897000
CY2021 us-gaap Interest Paid Net
InterestPaidNet
39029000
CY2020 us-gaap Interest Paid Net
InterestPaidNet
24024000
CY2021 us-gaap Use Of Estimates
UseOfEstimates
<p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 6pt 0pt;"><span style="font-style:italic;font-weight:bold;">Use of Estimates</span></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-indent:36pt;margin:0pt;">The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenues and expenses, and related disclosures in the consolidated financial statements and accompanying notes. Management bases its estimates on historical experience and on assumptions believed to be reasonable under the circumstances. Actual results could differ materially from those estimates.</p>
CY2021 us-gaap Number Of Operating Segments
NumberOfOperatingSegments
1
CY2021 us-gaap Concentration Risk Credit Risk
ConcentrationRiskCreditRisk
<p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt 0pt 6pt 0pt;"><span style="font-style:italic;font-weight:bold;">Concentration of Credit Risks</span></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-indent:36pt;margin:0pt;">The Company invests in a variety of financial instruments and, based on its policy, limits the amount of credit exposure with any one issuer, industry or geographic area for investments other than instruments backed by the US federal government. </p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-indent:36pt;margin:0pt;"><span style="visibility:hidden;">​</span></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-indent:36pt;margin:0pt;">The Company’s receivables primarily relate to amounts due under its collaboration and licensing agreements. Accordingly, the Company may be exposed to credit risk generally associated with pharmaceutical companies or specific to its collaboration agreements. The Company performs periodic evaluations of its customers and generally does not require collateral. For the year ended December 31, 2021, 2020, and 2019, the Company did not experience any material losses related to its receivables.</p>
CY2019 us-gaap Impairment Of Long Lived Assets To Be Disposed Of
ImpairmentOfLongLivedAssetsToBeDisposedOf
0
CY2020 us-gaap Impairment Of Long Lived Assets To Be Disposed Of
ImpairmentOfLongLivedAssetsToBeDisposedOf
0
CY2021 us-gaap Impairment Of Long Lived Assets To Be Disposed Of
ImpairmentOfLongLivedAssetsToBeDisposedOf
0
CY2021 us-gaap Advertising Expense
AdvertisingExpense
9300000
CY2020 us-gaap Advertising Expense
AdvertisingExpense
6300000
CY2019 us-gaap Advertising Expense
AdvertisingExpense
2400000
CY2021Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
75000000.0
CY2020Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
63400000
CY2021 us-gaap Net Income Loss
NetIncomeLoss
-199426000
CY2020 us-gaap Net Income Loss
NetIncomeLoss
-278017000
CY2019 us-gaap Net Income Loss
NetIncomeLoss
-236455000
CY2021 tbph Weighted Average Number Of Shares Outstanding Before Forfeitures
WeightedAverageNumberOfSharesOutstandingBeforeForfeitures
69518000
CY2020 tbph Weighted Average Number Of Shares Outstanding Before Forfeitures
WeightedAverageNumberOfSharesOutstandingBeforeForfeitures
62808000
CY2019 tbph Weighted Average Number Of Shares Outstanding Before Forfeitures
WeightedAverageNumberOfSharesOutstandingBeforeForfeitures
56452000
CY2021 tbph Incremental Common Shares Attributable To Dilutive Effect Of Common Share Subject To Forfeiture Incremental Common Shares Attributable To Dilutive Effect Of Common Share Subject To Forfeiture
IncrementalCommonSharesAttributableToDilutiveEffectOfCommonShareSubjectToForfeitureIncrementalCommonSharesAttributableToDilutiveEffectOfCommonShareSubjectToForfeiture
-57000
CY2020 tbph Incremental Common Shares Attributable To Dilutive Effect Of Common Share Subject To Forfeiture Incremental Common Shares Attributable To Dilutive Effect Of Common Share Subject To Forfeiture
IncrementalCommonSharesAttributableToDilutiveEffectOfCommonShareSubjectToForfeitureIncrementalCommonSharesAttributableToDilutiveEffectOfCommonShareSubjectToForfeiture
-463000
CY2019 tbph Incremental Common Shares Attributable To Dilutive Effect Of Common Share Subject To Forfeiture Incremental Common Shares Attributable To Dilutive Effect Of Common Share Subject To Forfeiture
IncrementalCommonSharesAttributableToDilutiveEffectOfCommonShareSubjectToForfeitureIncrementalCommonSharesAttributableToDilutiveEffectOfCommonShareSubjectToForfeiture
-842000
CY2021 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
69461000
CY2020 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
62345000
CY2019 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
55610000
CY2021 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-2.87
CY2020 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-4.46
CY2019 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-4.25
CY2021 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
14145000
CY2020 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
13229000
CY2019 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
13253000
CY2021 tbph Collaborative Arrangements Revenue
CollaborativeArrangementsRevenue
11463000
CY2020 tbph Collaborative Arrangements Revenue
CollaborativeArrangementsRevenue
26464000
CY2019 tbph Collaborative Arrangements Revenue
CollaborativeArrangementsRevenue
31245000
CY2018Q1 tbph Profit Loss Percentage As Per Collaboration Agreement
ProfitLossPercentageAsPerCollaborationAgreement
0.33
CY2021 tbph Profit Loss Percentage As Per Collaboration Agreement
ProfitLossPercentageAsPerCollaborationAgreement
0.35
CY2019Q4 us-gaap Restricted Cash
RestrictedCash
833000
CY2021Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
90796000
CY2020Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
82300000
CY2019Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
58897000
CY2021 us-gaap Foreign Currency Transaction Gain Loss Before Tax
ForeignCurrencyTransactionGainLossBeforeTax
-900000
CY2020 us-gaap Foreign Currency Transaction Gain Loss Before Tax
ForeignCurrencyTransactionGainLossBeforeTax
-300000
CY2019 us-gaap Foreign Currency Transaction Gain Loss Before Tax
ForeignCurrencyTransactionGainLossBeforeTax
200000
CY2021 tbph Collaborative Arrangement Research And Development Expenses Reimbursed To Entity
CollaborativeArrangementResearchAndDevelopmentExpensesReimbursedToEntity
7891000
CY2020 tbph Collaborative Arrangement Research And Development Expenses Reimbursed To Entity
CollaborativeArrangementResearchAndDevelopmentExpensesReimbursedToEntity
10078000
CY2019 tbph Collaborative Arrangement Research And Development Expenses Reimbursed To Entity
CollaborativeArrangementResearchAndDevelopmentExpensesReimbursedToEntity
5589000
CY2021 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
55311000
CY2020 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
71857000
CY2019 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
73414000
CY2021Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
89959000
CY2020Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
81467000
CY2019Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
58064000
CY2021Q4 us-gaap Restricted Cash
RestrictedCash
837000
CY2020Q4 us-gaap Restricted Cash
RestrictedCash
833000
CY2021Q4 us-gaap Available For Sale Debt Securities Amortized Cost Basis
AvailableForSaleDebtSecuritiesAmortizedCostBasis
133738000
CY2021Q4 us-gaap Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
1000
CY2021Q4 us-gaap Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
5000
CY2021Q4 us-gaap Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
133734000
CY2020Q4 us-gaap Available For Sale Debt Securities Amortized Cost Basis
AvailableForSaleDebtSecuritiesAmortizedCostBasis
211427000
CY2020Q4 us-gaap Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
53000
CY2020Q4 us-gaap Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
6000
CY2020Q4 us-gaap Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
211474000
CY2021 tbph Marketable Securities Maximum Contractual Maturity Period
MarketableSecuritiesMaximumContractualMaturityPeriod
P6M
CY2021 tbph Marketable Securities Average Contractual Maturity Period
MarketableSecuritiesAverageContractualMaturityPeriod
P2M
CY2020Q4 us-gaap Fair Value Assets Level1 To Level2 Transfers Amount
FairValueAssetsLevel1ToLevel2TransfersAmount
0
CY2021Q4 us-gaap Fair Value Assets Level1 To Level2 Transfers Amount
FairValueAssetsLevel1ToLevel2TransfersAmount
0
CY2021Q4 us-gaap Debt Securities Available For Sale Continuous Unrealized Loss Position Less Than12 Months
DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12Months
35017000
CY2021Q4 us-gaap Debt Securities Available For Sale Continuous Unrealized Loss Position Less Than12 Months Accumulated Loss
DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss
5000
CY2021Q4 us-gaap Debt Securities Available For Sale Unrealized Loss Position
DebtSecuritiesAvailableForSaleUnrealizedLossPosition
35017000
CY2021Q4 us-gaap Debt Securities Available For Sale Unrealized Loss Position Accumulated Loss
DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss
5000
CY2020Q4 us-gaap Debt Securities Available For Sale Continuous Unrealized Loss Position Less Than12 Months
DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12Months
44420000
CY2021Q3 tbph Sublease Monthly Base Rent
SubleaseMonthlyBaseRent
100000
CY2021Q3 tbph Sublease Percentage Of Increase In Annual Base Rent
SubleasePercentageOfIncreaseInAnnualBaseRent
0.03
CY2021Q3 us-gaap Sublease Income
SubleaseIncome
13100000
CY2020Q4 us-gaap Debt Securities Available For Sale Continuous Unrealized Loss Position Less Than12 Months Accumulated Loss
DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss
6000
CY2020Q4 us-gaap Debt Securities Available For Sale Unrealized Loss Position
DebtSecuritiesAvailableForSaleUnrealizedLossPosition
44420000
CY2020Q4 us-gaap Debt Securities Available For Sale Unrealized Loss Position Accumulated Loss
DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss
6000
CY2021Q4 us-gaap Debt Securities Available For Sale Accumulated Gross Unrealized Gain Loss Before Tax
DebtSecuritiesAvailableForSaleAccumulatedGrossUnrealizedGainLossBeforeTax
0
CY2020 us-gaap Proceeds From Sale Of Available For Sale Securities Debt
ProceedsFromSaleOfAvailableForSaleSecuritiesDebt
19900000
CY2019 us-gaap Proceeds From Sale Of Available For Sale Securities Debt
ProceedsFromSaleOfAvailableForSaleSecuritiesDebt
0
CY2021Q4 us-gaap Long Term Debt
LongTermDebt
616334000
CY2020Q4 us-gaap Long Term Debt
LongTermDebt
619170000
CY2021 us-gaap Operating Lease Cost
OperatingLeaseCost
7625000
CY2020 us-gaap Operating Lease Cost
OperatingLeaseCost
8732000
CY2021 us-gaap Interest Expense Debt
InterestExpenseDebt
44707000
CY2020 us-gaap Interest Expense Debt
InterestExpenseDebt
42625000
CY2019 us-gaap Interest Expense Debt
InterestExpenseDebt
28811000
CY2021 us-gaap Amortization Of Financing Costs
AmortizationOfFinancingCosts
2182000
CY2020 us-gaap Amortization Of Financing Costs
AmortizationOfFinancingCosts
1960000
CY2019 us-gaap Amortization Of Financing Costs
AmortizationOfFinancingCosts
3051000
CY2021 us-gaap Interest Expense
InterestExpense
46889000
CY2020 us-gaap Interest Expense
InterestExpense
44585000
CY2019 us-gaap Interest Expense
InterestExpense
31862000
CY2020 us-gaap Gains Losses On Extinguishment Of Debt
GainsLossesOnExtinguishmentOfDebt
-15500000
CY2021Q4 tbph Area Of Leased Space
AreaOfLeasedSpace
162000
CY2021 tbph Number Of Building Leased
NumberOfBuildingLeased
2
CY2020Q4 tbph Tenant Improvement Allowance
TenantImprovementAllowance
12100000
CY2021Q3 us-gaap Area Of Real Estate Property
AreaOfRealEstateProperty
8000
CY2021Q3 tbph Increase Decrease In Operating Lease Asset
IncreaseDecreaseInOperatingLeaseAsset
-1100000
CY2021Q3 us-gaap Increase Decrease In Operating Lease Liability
IncreaseDecreaseInOperatingLeaseLiability
-3000000.0
CY2021Q3 tbph Gain Loss On Modification Of Lease
GainLossOnModificationOfLease
1900000
CY2021Q3 tbph Area Of Property Subleased
AreaOfPropertySubleased
21000
CY2021Q4 us-gaap Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
39690000
CY2019 us-gaap Operating Lease Cost
OperatingLeaseCost
8123000
CY2021Q3 tbph Premium Over Proportionate Lease Payment Obligations
PremiumOverProportionateLeasePaymentObligations
3800000
CY2021Q3 tbph Percentage Of Excess Sublease Payments Received Shared With Lessor
PercentageOfExcessSubleasePaymentsReceivedSharedWithLessor
0.50
CY2021Q3 tbph Premium Over Proportionate Lease Payment Obligations Shared With Lessor
PremiumOverProportionateLeasePaymentObligationsSharedWithLessor
1900000
CY2021Q3 tbph Percentage Of Excess Sublease Payments Received Retained
PercentageOfExcessSubleasePaymentsReceivedRetained
0.50
CY2021 tbph Number Of Options To Extend
NumberOfOptionsToExtend
2
CY2021Q4 us-gaap Lessee Operating Lease Renewal Term
LesseeOperatingLeaseRenewalTerm
P5Y
CY2020Q4 us-gaap Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
43260000
CY2021Q4 us-gaap Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
503000
CY2020Q4 us-gaap Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
9867000
CY2021Q4 us-gaap Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
52681000
CY2020Q4 us-gaap Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
47220000
CY2021Q4 us-gaap Operating Lease Liability
OperatingLeaseLiability
53184000
CY2020Q4 us-gaap Operating Lease Liability
OperatingLeaseLiability
57087000
CY2021 us-gaap Operating Lease Payments
OperatingLeasePayments
8971000
CY2020 us-gaap Operating Lease Payments
OperatingLeasePayments
3804000
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due Next Twelve Months
LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
9390000
CY2021Q4 us-gaap Restructuring Reserve
RestructuringReserve
9550000
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Two
LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
9655000
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Three
LesseeOperatingLeaseLiabilityPaymentsDueYearThree
9865000
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Four
LesseeOperatingLeaseLiabilityPaymentsDueYearFour
10133000
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Five
LesseeOperatingLeaseLiabilityPaymentsDueYearFive
10425000
CY2021 us-gaap Depreciation
Depreciation
3500000
CY2020 us-gaap Depreciation
Depreciation
3300000
CY2019 us-gaap Depreciation
Depreciation
3300000
CY2014Q2 tbph Share Based Compensation Arrangement By Share Based Payment Award Number Of Plans
ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfPlans
3
CY2021Q3 tbph Share Based Compensation Allocation Of Recognized Period Costs Capitalized Reversed Amount
ShareBasedCompensationAllocationOfRecognizedPeriodCostsCapitalizedReversedAmount
2800000
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Plan Modification Incremental Compensation Cost
ShareBasedCompensationArrangementByShareBasedPaymentAwardPlanModificationIncrementalCompensationCost
2800000
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due After Year Five
LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive
36552000
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
86020000
CY2021Q4 tbph Tenant Improvement Allowance
TenantImprovementAllowance
10214000
CY2021Q4 us-gaap Lessee Operating Lease Liability Undiscounted Excess Amount
LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
22622000
CY2021Q4 us-gaap Operating Lease Liability
OperatingLeaseLiability
53184000
CY2021Q4 us-gaap Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
P8Y3M18D
CY2021Q4 us-gaap Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
0.0864
CY2021Q4 us-gaap Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
52149000
CY2020Q4 us-gaap Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
62230000
CY2021Q4 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
38492000
CY2020Q4 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
45808000
CY2021Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
13657000
CY2020Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
16422000
CY2021 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
62061000
CY2020 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
62976000
CY2019 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
60450000
CY2021 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
62061000
CY2020 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
62976000
CY2019 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
60450000
CY2020Q4 us-gaap Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
82821000
CY2021Q4 us-gaap Deferred Tax Assets Capital Loss Carryforwards
DeferredTaxAssetsCapitalLossCarryforwards
19409000
CY2020Q4 us-gaap Deferred Tax Assets Capital Loss Carryforwards
DeferredTaxAssetsCapitalLossCarryforwards
19409000
CY2021Q4 us-gaap Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized
EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized
93551000
CY2021Q4 us-gaap Deferred Tax Assets Tax Credit Carryforwards Research
DeferredTaxAssetsTaxCreditCarryforwardsResearch
28372000
CY2020Q4 us-gaap Deferred Tax Assets Tax Credit Carryforwards Research
DeferredTaxAssetsTaxCreditCarryforwardsResearch
24075000
CY2021Q4 tbph Deferred Tax Assets Property Plant And Equipment And Intangible Assets
DeferredTaxAssetsPropertyPlantAndEquipmentAndIntangibleAssets
287177000
CY2020Q4 tbph Deferred Tax Assets Property Plant And Equipment And Intangible Assets
DeferredTaxAssetsPropertyPlantAndEquipmentAndIntangibleAssets
310187000
CY2021Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost
10432000
CY2020Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost
15087000
CY2021Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Reserves And Accruals Accrued Liabilities
DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities
3590000
CY2020Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Reserves And Accruals Accrued Liabilities
DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities
8145000
CY2021Q4 tbph Deferred Tax Assets Operating Lease Liabilities
DeferredTaxAssetsOperatingLeaseLiabilities
11607000
CY2020Q4 tbph Deferred Tax Assets Operating Lease Liabilities
DeferredTaxAssetsOperatingLeaseLiabilities
11662000
CY2021Q4 us-gaap Deferred Tax Assets Other
DeferredTaxAssetsOther
10505000
CY2020Q4 us-gaap Deferred Tax Assets Other
DeferredTaxAssetsOther
346000
CY2021 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-199577000
CY2020 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-286537000
CY2019 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-241677000
CY2021 us-gaap Current Income Tax Expense Benefit
CurrentIncomeTaxExpenseBenefit
-151000
CY2020 us-gaap Current Income Tax Expense Benefit
CurrentIncomeTaxExpenseBenefit
-8520000
CY2019 us-gaap Current Income Tax Expense Benefit
CurrentIncomeTaxExpenseBenefit
-5222000
CY2021 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
-151000
CY2020 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
-8520000
CY2019 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
-5222000
CY2021 us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
0.0008
CY2020 us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
0.0297
CY2019 us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
0.0216
CY2021 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
-200000
CY2020 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
-8500000
CY2019 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
-5200000
CY2021Q4 us-gaap Deferred Tax Liability Not Recognized Amount Of Unrecognized Deferred Tax Liability Undistributed Earnings Of Foreign Subsidiaries
DeferredTaxLiabilityNotRecognizedAmountOfUnrecognizedDeferredTaxLiabilityUndistributedEarningsOfForeignSubsidiaries
0
CY2020Q4 us-gaap Undistributed Earnings Of Foreign Subsidiaries
UndistributedEarningsOfForeignSubsidiaries
0
CY2021Q4 us-gaap Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
115606000
CY2021Q4 us-gaap Deferred Tax Assets Gross
DeferredTaxAssetsGross
486698000
CY2020Q4 us-gaap Deferred Tax Assets Gross
DeferredTaxAssetsGross
471732000
CY2021Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
477868000
CY2020Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
462711000
CY2021Q4 us-gaap Deferred Tax Assets Net
DeferredTaxAssetsNet
8830000
CY2020Q4 us-gaap Deferred Tax Assets Net
DeferredTaxAssetsNet
9021000
CY2021Q4 tbph Deferred Tax Liabilities Operating Lease Assets
DeferredTaxLiabilitiesOperatingLeaseAssets
8575000
CY2020Q4 tbph Deferred Tax Liabilities Operating Lease Assets
DeferredTaxLiabilitiesOperatingLeaseAssets
8680000
CY2021Q4 us-gaap Deferred Tax Liabilities Prepaid Expenses
DeferredTaxLiabilitiesPrepaidExpenses
254000
CY2020Q4 us-gaap Deferred Tax Liabilities Prepaid Expenses
DeferredTaxLiabilitiesPrepaidExpenses
341000
CY2021Q4 us-gaap Deferred Income Tax Liabilities
DeferredIncomeTaxLiabilities
8830000
CY2020Q4 us-gaap Deferred Income Tax Liabilities
DeferredIncomeTaxLiabilities
9021000
CY2020Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
462700000
CY2021Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
477900000
CY2019Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
58763000
CY2020 us-gaap Unrecognized Tax Benefits Decreases Resulting From Prior Period Tax Positions
UnrecognizedTaxBenefitsDecreasesResultingFromPriorPeriodTaxPositions
8059000
CY2020 us-gaap Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions
UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions
12743000
CY2020Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
63447000
CY2021 us-gaap Unrecognized Tax Benefits Decreases Resulting From Prior Period Tax Positions
UnrecognizedTaxBenefitsDecreasesResultingFromPriorPeriodTaxPositions
395000
CY2021 us-gaap Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions
UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions
11971000
CY2021Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
75023000
CY2021Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
75000000.0
CY2020Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
63400000
CY2021Q1 us-gaap Net Income Loss
NetIncomeLoss
-79679000
CY2021Q2 us-gaap Net Income Loss
NetIncomeLoss
-52405000
CY2021Q3 us-gaap Net Income Loss
NetIncomeLoss
-35308000
CY2021Q4 us-gaap Net Income Loss
NetIncomeLoss
-32034000
CY2021Q1 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-1.24
CY2021Q4 tbph Guarantees And Indemnifications Liability
GuaranteesAndIndemnificationsLiability
0
CY2020Q1 us-gaap Operating Expenses
OperatingExpenses
92338000
CY2020Q2 us-gaap Operating Expenses
OperatingExpenses
87184000
CY2020Q3 us-gaap Operating Expenses
OperatingExpenses
94872000
CY2021Q2 us-gaap Share Price
SharePrice
15.00
CY2021Q2 us-gaap Stock Issued During Period Shares New Issues
StockIssuedDuringPeriodSharesNewIssues
7705000
CY2021Q2 us-gaap Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
115600000
CY2021Q3 tbph Percentage Of Reduction In Workforce
PercentageOfReductionInWorkforce
0.75
CY2021Q3 tbph Number Of Employees Reduction In Workforce
NumberOfEmployeesReductionInWorkforce
270
CY2021Q4 tbph Percentage Of Reduction In Workforce
PercentageOfReductionInWorkforce
0.75
CY2021Q4 us-gaap Restructuring And Related Cost Expected Cost1
RestructuringAndRelatedCostExpectedCost1
17000000.0
CY2021 tbph Non Cash Charges Related To Modification Of Equity Awards For Terminated And Remaining Employee
NonCashChargesRelatedToModificationOfEquityAwardsForTerminatedAndRemainingEmployee
15000000.0
CY2021 us-gaap Restructuring Charges
RestructuringCharges
20100000
CY2021 us-gaap Restructuring Reserve Accrual Adjustment1
RestructuringReserveAccrualAdjustment1
11867000
CY2021 us-gaap Payments For Restructuring
PaymentsForRestructuring
2317000
CY2021Q1 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
14257000
CY2021Q2 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
12914000
CY2021Q3 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
13194000
CY2021Q4 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
14946000
CY2021Q1 us-gaap Operating Expenses
OperatingExpenses
98149000
CY2021Q2 us-gaap Operating Expenses
OperatingExpenses
77024000
CY2021Q3 us-gaap Operating Expenses
OperatingExpenses
66809000
CY2021Q4 us-gaap Operating Expenses
OperatingExpenses
71113000
CY2021Q1 us-gaap Operating Income Loss
OperatingIncomeLoss
-83892000
CY2021Q2 us-gaap Operating Income Loss
OperatingIncomeLoss
-64110000
CY2021Q3 us-gaap Operating Income Loss
OperatingIncomeLoss
-53615000
CY2021Q4 us-gaap Operating Income Loss
OperatingIncomeLoss
-56167000
CY2021Q2 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.80
CY2021Q3 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.48
CY2021Q4 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.43
CY2020Q1 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
19862000
CY2020Q2 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
15008000
CY2020Q3 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
18257000
CY2020Q4 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
18730000
CY2020Q4 us-gaap Operating Expenses
OperatingExpenses
95220000
CY2020Q1 us-gaap Operating Income Loss
OperatingIncomeLoss
-72476000
CY2020Q2 us-gaap Operating Income Loss
OperatingIncomeLoss
-72176000
CY2020Q3 us-gaap Operating Income Loss
OperatingIncomeLoss
-76615000
CY2020Q4 us-gaap Operating Income Loss
OperatingIncomeLoss
-76490000
CY2020Q1 us-gaap Net Income Loss
NetIncomeLoss
-83053000
CY2020Q2 us-gaap Net Income Loss
NetIncomeLoss
-62887000
CY2020Q3 us-gaap Net Income Loss
NetIncomeLoss
-73643000
CY2020Q4 us-gaap Net Income Loss
NetIncomeLoss
-58434000
CY2020Q1 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-1.40
CY2020Q2 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-1.00
CY2020Q3 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-1.16
CY2020Q4 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.92
CY2021 tbph Profit Loss Percentage As Per Collaboration Agreement
ProfitLossPercentageAsPerCollaborationAgreement
0.35
CY2021 dei Auditor Name
AuditorName
Ernst & Young LLP
CY2021 dei Auditor Location
AuditorLocation
Redwood City, California

Files In Submission

Name View Source Status
0001558370-22-002373-index-headers.html Edgar Link pending
0001558370-22-002373-index.html Edgar Link pending
0001558370-22-002373.txt Edgar Link pending
0001558370-22-002373-xbrl.zip Edgar Link pending
FilingSummary.xml Edgar Link unprocessable
Financial_Report.xlsx Edgar Link pending
MetaLinks.json Edgar Link pending
R1.htm Edgar Link pending
R10.htm Edgar Link pending
R11.htm Edgar Link pending
R12.htm Edgar Link pending
R13.htm Edgar Link pending
R14.htm Edgar Link pending
R15.htm Edgar Link pending
R16.htm Edgar Link pending
R17.htm Edgar Link pending
R18.htm Edgar Link pending
R19.htm Edgar Link pending
R2.htm Edgar Link pending
R20.htm Edgar Link pending
R21.htm Edgar Link pending
R22.htm Edgar Link pending
R23.htm Edgar Link pending
R24.htm Edgar Link pending
R25.htm Edgar Link pending
R26.htm Edgar Link pending
R27.htm Edgar Link pending
R28.htm Edgar Link pending
R29.htm Edgar Link pending
R3.htm Edgar Link pending
R30.htm Edgar Link pending
R31.htm Edgar Link pending
R32.htm Edgar Link pending
R33.htm Edgar Link pending
R34.htm Edgar Link pending
R35.htm Edgar Link pending
R36.htm Edgar Link pending
R37.htm Edgar Link pending
R38.htm Edgar Link pending
R39.htm Edgar Link pending
R4.htm Edgar Link pending
R40.htm Edgar Link pending
R41.htm Edgar Link pending
R42.htm Edgar Link pending
R43.htm Edgar Link pending
R44.htm Edgar Link pending
R45.htm Edgar Link pending
R46.htm Edgar Link pending
R47.htm Edgar Link pending
R48.htm Edgar Link pending
R49.htm Edgar Link pending
R5.htm Edgar Link pending
R50.htm Edgar Link pending
R51.htm Edgar Link pending
R52.htm Edgar Link pending
R53.htm Edgar Link pending
R54.htm Edgar Link pending
R55.htm Edgar Link pending
R56.htm Edgar Link pending
R57.htm Edgar Link pending
R58.htm Edgar Link pending
R59.htm Edgar Link pending
R6.htm Edgar Link pending
R60.htm Edgar Link pending
R61.htm Edgar Link pending
R62.htm Edgar Link pending
R63.htm Edgar Link pending
R64.htm Edgar Link pending
R65.htm Edgar Link pending
R66.htm Edgar Link pending
R67.htm Edgar Link pending
R68.htm Edgar Link pending
R69.htm Edgar Link pending
R7.htm Edgar Link pending
R70.htm Edgar Link pending
R71.htm Edgar Link pending
R72.htm Edgar Link pending
R73.htm Edgar Link pending
R74.htm Edgar Link pending
R75.htm Edgar Link pending
R76.htm Edgar Link pending
R77.htm Edgar Link pending
R78.htm Edgar Link pending
R79.htm Edgar Link pending
R8.htm Edgar Link pending
R80.htm Edgar Link pending
R81.htm Edgar Link pending
R82.htm Edgar Link pending
R9.htm Edgar Link pending
report.css Edgar Link pending
Show.js Edgar Link pending
tbph-20211231.xsd Edgar Link pending
tbph-20211231x10k.htm Edgar Link pending
tbph-20211231x10k006.jpg Edgar Link pending
tbph-20211231x10k008.jpg Edgar Link pending
tbph-20211231x10k_htm.xml Edgar Link completed
tbph-20211231xex10d69.htm Edgar Link pending
tbph-20211231xex10d70.htm Edgar Link pending
tbph-20211231xex10d71.htm Edgar Link pending
tbph-20211231xex10d72.htm Edgar Link pending
tbph-20211231xex10d72001.jpg Edgar Link pending
tbph-20211231xex10d72002.jpg Edgar Link pending
tbph-20211231xex10d72003.jpg Edgar Link pending
tbph-20211231xex10d72005.jpg Edgar Link pending
tbph-20211231xex21d1.htm Edgar Link pending
tbph-20211231xex23d1.htm Edgar Link pending
tbph-20211231xex23d2.htm Edgar Link pending
tbph-20211231xex31d1.htm Edgar Link pending
tbph-20211231xex31d2.htm Edgar Link pending
tbph-20211231xex32.htm Edgar Link pending
tbph-20211231_cal.xml Edgar Link unprocessable
tbph-20211231_def.xml Edgar Link unprocessable
tbph-20211231_lab.xml Edgar Link unprocessable
tbph-20211231_pre.xml Edgar Link unprocessable