2017 Form 10-K Financial Statement
#000114420418010286 Filed on February 22, 2018
Income Statement
Concept | 2017 | 2016 Q4 | 2016 Q3 |
---|---|---|---|
Revenue | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Cost Of Revenue | |||
YoY Change | |||
Gross Profit | |||
YoY Change | |||
Gross Profit Margin | |||
Selling, General & Admin | $7.467M | $3.480M | $2.100M |
YoY Change | -26.38% | 37.01% | 31.25% |
% of Gross Profit | |||
Research & Development | $18.78M | $6.730M | $7.061M |
YoY Change | -35.47% | -24.04% | -29.71% |
% of Gross Profit | |||
Depreciation & Amortization | $245.0K | $50.00K | $50.00K |
YoY Change | 56.05% | 66.67% | 150.0% |
% of Gross Profit | |||
Operating Expenses | $26.25M | $10.20M | $9.156M |
YoY Change | -33.12% | -10.45% | -21.41% |
Operating Profit | -$26.25M | -$9.156M | |
YoY Change | -33.12% | -21.41% | |
Interest Expense | $21.00K | $0.00 | $0.00 |
YoY Change | -43.24% | ||
% of Operating Profit | |||
Other Income/Expense, Net | $10.76M | $7.730M | $667.0K |
YoY Change | -6.03% | 7630.0% | -83.9% |
Pretax Income | -$15.49M | -$10.20M | -$9.156M |
YoY Change | -44.28% | -10.44% | -21.41% |
Income Tax | $0.00 | ||
% Of Pretax Income | |||
Net Earnings | -$15.17M | -$2.472M | -$8.489M |
YoY Change | -44.33% | -78.12% | 13.08% |
Net Earnings / Revenue | |||
Basic Earnings Per Share | -$0.02 | -$0.09 | |
Diluted Earnings Per Share | -$42.71M | -$0.02 | -$0.09 |
COMMON SHARES | |||
Basic Shares Outstanding | 103.8M shares | 91.44M shares | |
Diluted Shares Outstanding | 103.8M shares | 91.44M shares |
Balance Sheet
Concept | 2017 | 2016 Q4 | 2016 Q3 |
---|---|---|---|
SHORT-TERM ASSETS | |||
Cash & Short-Term Investments | $17.12M | $19.06M | $4.550M |
YoY Change | -10.18% | -8.45% | -85.7% |
Cash & Equivalents | $17.12M | $19.06M | $4.549M |
Short-Term Investments | |||
Other Short-Term Assets | $827.0K | $185.0K | $294.0K |
YoY Change | -67.12% | -97.15% | |
Inventory | |||
Prepaid Expenses | $295.0K | ||
Receivables | |||
Other Receivables | $0.00 | ||
Total Short-Term Assets | $17.94M | $21.57M | $7.640M |
YoY Change | -16.82% | -28.9% | -81.87% |
LONG-TERM ASSETS | |||
Property, Plant & Equipment | $872.0K | $905.0K | $580.0K |
YoY Change | -3.65% | 83.2% | 20.08% |
Goodwill | |||
YoY Change | |||
Intangibles | |||
YoY Change | |||
Long-Term Investments | |||
YoY Change | |||
Other Assets | $23.00K | $20.00K | $30.00K |
YoY Change | 0.0% | 100.0% | 200.0% |
Total Long-Term Assets | $895.0K | $928.0K | $610.0K |
YoY Change | -3.56% | 80.9% | 22.74% |
TOTAL ASSETS | |||
Total Short-Term Assets | $17.94M | $21.57M | $7.640M |
Total Long-Term Assets | $895.0K | $928.0K | $610.0K |
Total Assets | $18.84M | $22.50M | $8.250M |
YoY Change | -16.27% | -27.07% | -80.65% |
SHORT-TERM LIABILITIES | |||
YoY Change | |||
Accounts Payable | $2.020M | $1.993M | $4.240M |
YoY Change | 1.35% | -54.81% | -29.64% |
Accrued Expenses | $3.600M | $2.627M | $2.830M |
YoY Change | 22.45% | 784.51% | 1059.84% |
Deferred Revenue | |||
YoY Change | |||
Short-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Long-Term Debt Due | |||
YoY Change | |||
Total Short-Term Liabilities | $9.793M | $19.76M | $14.01M |
YoY Change | -50.43% | 26.85% | -19.02% |
LONG-TERM LIABILITIES | |||
Long-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Other Long-Term Liabilities | $402.0K | $490.0K | $210.0K |
YoY Change | -18.29% | 81.48% | 5.0% |
Total Long-Term Liabilities | $402.0K | $490.0K | $210.0K |
YoY Change | -18.29% | 81.48% | 5.0% |
TOTAL LIABILITIES | |||
Total Short-Term Liabilities | $9.793M | $19.76M | $14.01M |
Total Long-Term Liabilities | $402.0K | $490.0K | $210.0K |
Total Liabilities | $8.281M | $20.25M | $12.72M |
YoY Change | -55.6% | 27.82% | -27.31% |
SHAREHOLDERS EQUITY | |||
Retained Earnings | -$172.0M | ||
YoY Change | |||
Common Stock | $175.9M | ||
YoY Change | |||
Preferred Stock | |||
YoY Change | |||
Treasury Stock (at cost) | |||
YoY Change | |||
Treasury Stock Shares | |||
Shareholders Equity | $10.56M | $3.845M | -$4.480M |
YoY Change | |||
Total Liabilities & Shareholders Equity | $18.84M | $22.50M | $8.250M |
YoY Change | -16.27% | -27.07% | -80.65% |
Cashflow Statement
Concept | 2017 | 2016 Q4 | 2016 Q3 |
---|---|---|---|
OPERATING ACTIVITIES | |||
Net Income | -$15.17M | -$2.472M | -$8.489M |
YoY Change | -44.33% | -78.12% | 13.08% |
Depreciation, Depletion And Amortization | $245.0K | $50.00K | $50.00K |
YoY Change | 56.05% | 66.67% | 150.0% |
Cash From Operating Activities | -$20.20M | -$10.38M | -$5.990M |
YoY Change | -27.59% | -5.38% | -60.62% |
INVESTING ACTIVITIES | |||
Capital Expenditures | $212.0K | -$370.0K | -$150.0K |
YoY Change | -62.74% | 825.0% | -62.5% |
Acquisitions | |||
YoY Change | |||
Other Investing Activities | |||
YoY Change | |||
Cash From Investing Activities | -$212.0K | -$370.0K | -$150.0K |
YoY Change | -62.74% | 825.0% | -62.5% |
FINANCING ACTIVITIES | |||
Cash Dividend Paid | |||
YoY Change | |||
Common Stock Issuance & Retirement, Net | $0.00 | $300.0K | |
YoY Change | -100.0% | ||
Debt Paid & Issued, Net | |||
YoY Change | |||
Cash From Financing Activities | 18.48M | 25.26M | 640.0K |
YoY Change | -30.82% | 126200.0% | -98.5% |
NET CHANGE | |||
Cash From Operating Activities | -20.20M | -10.38M | -5.990M |
Cash From Investing Activities | -212.0K | -370.0K | -150.0K |
Cash From Financing Activities | 18.48M | 25.26M | 640.0K |
Net Change In Cash | -1.939M | 14.51M | -5.500M |
YoY Change | 9.98% | -232.03% | -120.33% |
FREE CASH FLOW | |||
Cash From Operating Activities | -$20.20M | -$10.38M | -$5.990M |
Capital Expenditures | $212.0K | -$370.0K | -$150.0K |
Free Cash Flow | -$20.42M | -$10.01M | -$5.840M |
YoY Change | -28.29% | -8.42% | -60.57% |
Facts In Submission
Frame | Concept Type | Concept / XBRL Key | Value | Unit |
---|---|---|---|---|
CY2015 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
46000000 | USD |
CY2016Q4 | syn |
Accrued Clinical Consulting Services
AccruedClinicalConsultingServices
|
2211000 | USD |
CY2017Q4 | syn |
Accrued Manufacturing Costs
AccruedManufacturingCosts
|
661000 | USD |
CY2017 | dei |
Entity Well Known Seasoned Issuer
EntityWellKnownSeasonedIssuer
|
No | |
CY2017 | dei |
Entity Voluntary Filers
EntityVoluntaryFilers
|
No | |
CY2017 | dei |
Entity Current Reporting Status
EntityCurrentReportingStatus
|
Yes | |
CY2017 | dei |
Entity Filer Category
EntityFilerCategory
|
Accelerated Filer | |
CY2017Q2 | dei |
Entity Public Float
EntityPublicFloat
|
64400000 | USD |
CY2017 | dei |
Trading Symbol
TradingSymbol
|
SYN | |
CY2018Q1 | dei |
Entity Common Stock Shares Outstanding
EntityCommonStockSharesOutstanding
|
128566886 | shares |
CY2016Q4 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
19055000 | USD |
CY2016Q4 | us-gaap |
Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
|
2515000 | USD |
CY2016Q4 | us-gaap |
Assets Current
AssetsCurrent
|
21570000 | USD |
CY2016Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
905000 | USD |
CY2016Q4 | syn |
Deposits And Other Assets Noncurrent
DepositsAndOtherAssetsNoncurrent
|
23000 | USD |
CY2016Q4 | us-gaap |
Assets
Assets
|
22498000 | USD |
CY2016Q4 | us-gaap |
Accounts Payable Current
AccountsPayableCurrent
|
1993000 | USD |
CY2016Q4 | us-gaap |
Accrued Liabilities Current
AccruedLiabilitiesCurrent
|
2627000 | USD |
CY2016Q4 | us-gaap |
Liabilities Current
LiabilitiesCurrent
|
19757000 | USD |
CY2016Q4 | us-gaap |
Liabilities
Liabilities
|
20249000 | USD |
CY2017Q4 | us-gaap |
Common Stock Value
CommonStockValue
|
129000 | USD |
CY2016Q4 | us-gaap |
Common Stock Value
CommonStockValue
|
117000 | USD |
CY2017Q4 | us-gaap |
Additional Paid In Capital Common Stock
AdditionalPaidInCapitalCommonStock
|
192545000 | USD |
CY2016Q4 | us-gaap |
Additional Paid In Capital Common Stock
AdditionalPaidInCapitalCommonStock
|
175762000 | USD |
CY2017Q4 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-194170000 | USD |
CY2016Q4 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-172034000 | USD |
CY2017Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
-1496000 | USD |
CY2016Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
3845000 | USD |
CY2017Q4 | us-gaap |
Minority Interest
MinorityInterest
|
-1914000 | USD |
CY2016Q4 | us-gaap |
Minority Interest
MinorityInterest
|
-1596000 | USD |
CY2017Q4 | us-gaap |
Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
|
-3410000 | USD |
CY2016Q4 | us-gaap |
Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
|
2249000 | USD |
CY2017Q4 | us-gaap |
Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
|
18838000 | USD |
CY2016Q4 | us-gaap |
Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
|
22498000 | USD |
CY2017Q4 | syn |
Warrant Liabilities
WarrantLiabilities
|
4083000 | USD |
CY2016Q4 | syn |
Warrant Liabilities
WarrantLiabilities
|
14821000 | USD |
CY2017Q4 | us-gaap |
Accrued Employee Benefits Current
AccruedEmployeeBenefitsCurrent
|
2074000 | USD |
CY2016Q4 | us-gaap |
Accrued Employee Benefits Current
AccruedEmployeeBenefitsCurrent
|
313000 | USD |
CY2017Q4 | us-gaap |
Deferred Rent Credit Current
DeferredRentCreditCurrent
|
90000 | USD |
CY2016Q4 | us-gaap |
Deferred Rent Credit Current
DeferredRentCreditCurrent
|
3000 | USD |
CY2017Q4 | us-gaap |
Deferred Rent Credit Noncurrent
DeferredRentCreditNoncurrent
|
402000 | USD |
CY2016Q4 | us-gaap |
Deferred Rent Credit Noncurrent
DeferredRentCreditNoncurrent
|
492000 | USD |
CY2016 | us-gaap |
Operating Expenses
OperatingExpenses
|
39252000 | USD |
CY2016 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-39252000 | USD |
CY2016 | us-gaap |
Investment Income Interest
InvestmentIncomeInterest
|
37000 | USD |
CY2016 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
11449000 | USD |
CY2016 | us-gaap |
Net Income Loss Attributable To Noncontrolling Interest
NetIncomeLossAttributableToNoncontrollingInterest
|
-548000 | USD |
CY2016 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-27255000 | USD |
CY2016 | us-gaap |
Fair Value Adjustment Of Warrants
FairValueAdjustmentOfWarrants
|
-11412000 | USD |
CY2015 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
8074000 | USD |
CY2015 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-40980000 | USD |
CY2015 | us-gaap |
Net Income Loss Attributable To Noncontrolling Interest
NetIncomeLossAttributableToNoncontrollingInterest
|
-1048000 | USD |
CY2015 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-43737000 | USD |
CY2017 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.18 | |
CY2016 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.29 | |
CY2015 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.54 | |
CY2017 | us-gaap |
Preferred Stock Dividends Income Statement Impact
PreferredStockDividendsIncomeStatementImpact
|
6962000 | USD |
CY2016 | us-gaap |
Preferred Stock Dividends Income Statement Impact
PreferredStockDividendsIncomeStatementImpact
|
0 | USD |
CY2015 | us-gaap |
Preferred Stock Dividends Income Statement Impact
PreferredStockDividendsIncomeStatementImpact
|
0 | USD |
CY2017 | us-gaap |
Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
|
-22136000 | USD |
CY2016 | us-gaap |
Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
|
-27255000 | USD |
CY2015 | us-gaap |
Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
|
-43737000 | USD |
CY2017 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
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CY2016 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
94290436 | shares |
CY2015 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
80705692 | shares |
CY2016 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
4009000 | USD |
CY2016 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
-7004000 | USD |
CY2016 | syn |
Increase Decrease In Deposits And Other Assets
IncreaseDecreaseInDepositsAndOtherAssets
|
9000 | USD |
CY2016 | us-gaap |
Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
|
-2420000 | USD |
CY2016 | us-gaap |
Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
|
2330000 | USD |
CY2016 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-27901000 | USD |
CY2016 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
569000 | USD |
CY2016 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
26707000 | USD |
CY2016 | us-gaap |
Cash Period Increase Decrease
CashPeriodIncreaseDecrease
|
-1763000 | USD |
CY2015Q4 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
20818000 | USD |
CY2016 | us-gaap |
Increase Decrease In Deferred Compensation
IncreaseDecreaseInDeferredCompensation
|
207000 | USD |
CY2017 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
3409000 | USD |
CY2017 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
-1688000 | USD |
CY2017 | syn |
Increase Decrease In Deposits And Other Assets
IncreaseDecreaseInDepositsAndOtherAssets
|
0 | USD |
CY2017 | us-gaap |
Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
|
27000 | USD |
CY2017 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-20204000 | USD |
CY2017 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
212000 | USD |
CY2017 | us-gaap |
Net Cash Provided By Used In Investing Activities
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|
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CY2017 | syn |
Proceeds From Issuance Of Common Stock For Stock Option And Warrants Exercises
ProceedsFromIssuanceOfCommonStockForStockOptionAndWarrantsExercises
|
166000 | USD |
CY2017 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
18477000 | USD |
CY2017 | us-gaap |
Cash Period Increase Decrease
CashPeriodIncreaseDecrease
|
-1939000 | USD |
CY2017 | us-gaap |
Increase Decrease In Employee Related Liabilities
IncreaseDecreaseInEmployeeRelatedLiabilities
|
1761000 | USD |
CY2017 | us-gaap |
Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
|
-1101000 | USD |
CY2017 | us-gaap |
Increase Decrease In Deferred Compensation
IncreaseDecreaseInDeferredCompensation
|
-3000 | USD |
CY2016 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
157000 | USD |
CY2017 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
245000 | USD |
CY2017 | us-gaap |
Proceeds From Issuance Or Sale Of Equity
ProceedsFromIssuanceOrSaleOfEquity
|
6358000 | USD |
CY2016 | us-gaap |
Proceeds From Issuance Or Sale Of Equity
ProceedsFromIssuanceOrSaleOfEquity
|
1509000 | USD |
CY2017 | us-gaap |
Proceeds From Issuance Of Convertible Preferred Stock
ProceedsFromIssuanceOfConvertiblePreferredStock
|
11953000 | USD |
CY2016 | us-gaap |
Proceeds From Issuance Of Convertible Preferred Stock
ProceedsFromIssuanceOfConvertiblePreferredStock
|
0 | USD |
CY2017Q4 | us-gaap |
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
|
429000 | USD |
CY2016Q4 | syn |
Accrued Vendor Payments
AccruedVendorPayments
|
400000 | USD |
CY2017Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
14000 | USD |
CY2016Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
2000 | USD |
CY2017 | syn |
Issue Of Stock For Exclusive Channel Collaboration Agreement
IssueOfStockForExclusiveChannelCollaborationAgreement
|
0 | USD |
CY2016 | syn |
Issue Of Stock For Exclusive Channel Collaboration Agreement
IssueOfStockForExclusiveChannelCollaborationAgreement
|
0 | USD |
CY2015 | syn |
Issue Of Stock For Exclusive Channel Collaboration Agreement
IssueOfStockForExclusiveChannelCollaborationAgreement
|
-3000000 | USD |
CY2015 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
72000 | USD |
CY2015 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
7971000 | USD |
CY2016Q4 | syn |
Accrued Manufacturing Costs
AccruedManufacturingCosts
|
14000 | USD |
CY2017 | us-gaap |
Dividends Preferred Stock
DividendsPreferredStock
|
73000 | USD |
CY2015 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
3198000 | USD |
CY2017 | syn |
Stock Issued For Milestone Payments
StockIssuedForMilestonePayments
|
0 | USD |
CY2016 | syn |
Stock Issued For Milestone Payments
StockIssuedForMilestonePayments
|
0 | USD |
CY2015 | syn |
Stock Issued For Milestone Payments
StockIssuedForMilestonePayments
|
-1350000 | USD |
CY2017Q4 | us-gaap |
Accrued Bonuses Current
AccruedBonusesCurrent
|
1283000 | USD |
CY2016Q4 | us-gaap |
Accrued Bonuses Current
AccruedBonusesCurrent
|
0 | USD |
CY2017Q4 | us-gaap |
Accrued Vacation Current
AccruedVacationCurrent
|
201000 | USD |
CY2016Q4 | us-gaap |
Accrued Vacation Current
AccruedVacationCurrent
|
261000 | USD |
CY2017Q4 | us-gaap |
Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
|
2074000 | USD |
CY2016Q4 | us-gaap |
Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
|
313000 | USD |
CY2017Q4 | us-gaap |
Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
|
0.001 | |
CY2016Q4 | us-gaap |
Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
|
0.001 | |
CY2017Q4 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
350000000 | shares |
CY2016Q4 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
350000000 | shares |
CY2017Q4 | us-gaap |
Common Stock Shares Issued
CommonStockSharesIssued
|
128648365 | shares |
CY2016Q4 | us-gaap |
Common Stock Shares Issued
CommonStockSharesIssued
|
117254196 | shares |
CY2017Q4 | us-gaap |
Common Stock Shares Outstanding
CommonStockSharesOutstanding
|
128566886 | shares |
CY2016Q4 | us-gaap |
Common Stock Shares Outstanding
CommonStockSharesOutstanding
|
117172714 | shares |
CY2014Q4 | us-gaap |
Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
|
9556000 | USD |
CY2015 | us-gaap |
Adjustments To Additional Paid In Capital Share Based Compensation Stock Options Requisite Service Period Recognition
AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationStockOptionsRequisiteServicePeriodRecognition
|
3198000 | USD |
CY2016 | us-gaap |
Adjustments To Additional Paid In Capital Share Based Compensation Stock Options Requisite Service Period Recognition
AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationStockOptionsRequisiteServicePeriodRecognition
|
4009000 | USD |
CY2017 | us-gaap |
Adjustments To Additional Paid In Capital Share Based Compensation Stock Options Requisite Service Period Recognition
AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationStockOptionsRequisiteServicePeriodRecognition
|
3409000 | USD |
CY2015 | us-gaap |
Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
|
42643000 | USD |
CY2016 | us-gaap |
Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
|
24384000 | USD |
CY2015 | syn |
Stock Issued During Period Valuemilestone Payment
StockIssuedDuringPeriodValuemilestonePayment
|
1350000 | USD |
CY2015 | syn |
Stock Issued During Period Value For Exclusive Channel Collaboration Agreement
StockIssuedDuringPeriodValueForExclusiveChannelCollaborationAgreement
|
3000000 | USD |
CY2015 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
41000 | USD |
CY2016 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
814000 | USD |
CY2017 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
166000 | USD |
CY2015 | syn |
Issuance Value Of Common Stock Upon Exercise Of Warrants
IssuanceValueOfCommonStockUponExerciseOfWarrants
|
0 | USD |
CY2016 | us-gaap |
Adjustments To Additional Paid In Capital Warrant Issued
AdjustmentsToAdditionalPaidInCapitalWarrantIssued
|
15667000 | USD |
CY2016 | syn |
Stock Issued During Period At Market Offering Value
StockIssuedDuringPeriodAtMarketOfferingValue
|
1509000 | USD |
CY2017 | syn |
Stock Issued During Period At Market Offering Value
StockIssuedDuringPeriodAtMarketOfferingValue
|
6358000 | USD |
CY2017 | syn |
Adjustments To Additional Paid In Capital Convertible Preferred Stock With Conversion Feature
AdjustmentsToAdditionalPaidInCapitalConvertiblePreferredStockWithConversionFeature
|
0 | USD |
CY2017 | us-gaap |
Adjustments To Additional Paid In Capital Stock Issued Issuance Costs
AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts
|
27000 | USD |
CY2015 | syn |
Increase Decrease In Deposits And Other Assets
IncreaseDecreaseInDepositsAndOtherAssets
|
8000 | USD |
CY2015 | us-gaap |
Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
|
3417000 | USD |
CY2015 | us-gaap |
Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
|
-1001000 | USD |
CY2015 | us-gaap |
Increase Decrease In Employee Related Liabilities
IncreaseDecreaseInEmployeeRelatedLiabilities
|
-261000 | USD |
CY2015 | us-gaap |
Increase Decrease In Deferred Compensation
IncreaseDecreaseInDeferredCompensation
|
288000 | USD |
CY2015 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-38890000 | USD |
CY2015 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
501000 | USD |
CY2015 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
-501000 | USD |
CY2015 | us-gaap |
Proceeds From Issuance Of Convertible Preferred Stock
ProceedsFromIssuanceOfConvertiblePreferredStock
|
0 | USD |
CY2015 | syn |
Proceeds From Issuance Of Common Stock For Stock Option And Warrants Exercises
ProceedsFromIssuanceOfCommonStockForStockOptionAndWarrantsExercises
|
41000 | USD |
CY2015 | us-gaap |
Proceeds From Issuance Or Sale Of Equity
ProceedsFromIssuanceOrSaleOfEquity
|
0 | USD |
CY2017 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
0 | USD |
CY2016 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
25000000 | USD |
CY2017 | syn |
Direct Offering Cost
DirectOfferingCost
|
0 | USD |
CY2016 | syn |
Direct Offering Cost
DirectOfferingCost
|
616000 | USD |
CY2015 | syn |
Direct Offering Cost
DirectOfferingCost
|
3357000 | USD |
CY2015 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
42684000 | USD |
CY2015 | us-gaap |
Cash Period Increase Decrease
CashPeriodIncreaseDecrease
|
3293000 | USD |
CY2014Q4 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
17525000 | USD |
CY2017Q1 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-8149000 | USD |
CY2017Q2 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-6475000 | USD |
CY2017Q3 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-5842000 | USD |
CY2017Q4 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-5783000 | USD |
CY2017Q1 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-3058000 | USD |
CY2017Q2 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-4315000 | USD |
CY2017Q3 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-10930000 | USD |
CY2017Q4 | us-gaap |
Net Income Loss
NetIncomeLoss
|
2812000 | USD |
CY2017Q1 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-0.02 | |
CY2017Q2 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-0.03 | |
CY2017Q3 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-0.14 | |
CY2017Q4 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
0.02 | |
CY2017Q1 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-0.02 | |
CY2017Q2 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-0.03 | |
CY2017Q3 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-0.14 | |
CY2017Q4 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
0.02 | |
CY2017Q1 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
117447260 | shares |
CY2017Q2 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
123005220 | shares |
CY2017Q3 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
128279674 | shares |
CY2017Q4 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
128566883 | shares |
CY2017 | us-gaap |
Use Of Estimates
UseOfEstimates
|
<div style="MARGIN: 0pt 0px; FONT: 10pt Times New Roman, Times, Serif "> <div style="CLEAR:both; FONT-FAMILY:Times New Roman;FONT-SIZE: 10pt;MARGIN: 0pt 0px; FONT: 10pt Times New Roman, Times, Serif" align="justify"></div> <div style="CLEAR:both; FONT-FAMILY:Times New Roman;FONT-SIZE: 10pt;MARGIN: 0pt 0px; FONT: 10pt Times New Roman, Times, Serif" align="justify"><b><i>Use of Estimates</i></b></div> <div style="CLEAR:both; FONT-FAMILY:Times New Roman;FONT-SIZE: 10pt;MARGIN: 0pt 0px; FONT: 10pt Times New Roman, Times, Serif" align="justify"> </div> <div style="CLEAR:both; FONT-FAMILY:Times New Roman;FONT-SIZE: 10pt;MARGIN: 0pt 0px; FONT: 10pt Times New Roman, Times, Serif" align="justify">The preparation of consolidated financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect the amounts reported in the consolidated financial statements and accompanying notes. Such estimates and assumptions impact, among others, the following: the estimated useful lives for property and equipment, fair value of warrants, preferred stock and stock options granted for services or compensation, respectively, estimates of the probability and potential magnitude of contingent liabilities, and the valuation allowance for deferred tax assets due to continuing and expected future operating losses.</div> <div style="CLEAR:both; FONT-FAMILY:Times New Roman;FONT-SIZE: 10pt;MARGIN: 0pt 0px; FONT: 10pt Times New Roman, Times, Serif" align="justify"> </div> <div style="CLEAR:both; FONT-FAMILY:Times New Roman;FONT-SIZE: 10pt;MARGIN: 0pt 0px; FONT: 10pt Times New Roman, Times, Serif" align="justify">Making estimates requires management to exercise significant judgment. It is at least reasonably possible that the estimate of the effect of a condition, situation or set of consolidated financial statements, which management considered in formulating its estimate could change in the near term due to one or more future confirming events. Accordingly, actual results could differ from those estimates.</div> </div><table border="0" style="width:100%; table-layout:fixed;" cellspacing="0" cellpadding="0"><tr><td></td></tr></table> | |
CY2017Q1 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
117447260 | shares |
CY2017Q2 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
123005220 | shares |
CY2017Q3 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
128279674 | shares |
CY2017Q4 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
150847262 | shares |
CY2016Q4 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-0.02 | |
CY2016Q1 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
90826752 | shares |
CY2016Q2 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
91015733 | shares |
CY2016Q3 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
91441687 | shares |
CY2016Q4 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
103804308 | shares |
CY2016Q1 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
90826752 | shares |
CY2016Q2 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
93930540 | shares |
CY2016Q3 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
91441687 | shares |
CY2016Q1 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-10581000 | USD |
CY2016Q2 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-9311000 | USD |
CY2016Q3 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-9156000 | USD |
CY2016Q4 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-10204000 | USD |
CY2016Q1 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-11078000 | USD |
CY2016Q2 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-5764000 | USD |
CY2016Q3 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-8489000 | USD |
CY2016Q4 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-2472000 | USD |
CY2016Q1 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-0.12 | |
CY2016Q2 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-0.06 | |
CY2016Q3 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-0.09 | |
CY2016Q4 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-0.02 | |
CY2016Q1 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-0.12 | |
CY2016Q2 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-0.10 | |
CY2016Q3 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-0.09 | |
CY2016Q4 | us-gaap |
Equity Method Investment Ownership Percentage
EquityMethodInvestmentOwnershipPercentage
|
0.885 | pure |
CY2016Q4 | us-gaap |
Minority Interest Ownership Percentage By Parent
MinorityInterestOwnershipPercentageByParent
|
0.115 | pure |
CY2017 | us-gaap |
Current Federal Tax Expense Benefit
CurrentFederalTaxExpenseBenefit
|
-5267000 | USD |
CY2016 | us-gaap |
Current Federal Tax Expense Benefit
CurrentFederalTaxExpenseBenefit
|
-9453000 | USD |
CY2017Q4 | us-gaap |
Accrued Liabilities Current And Noncurrent
AccruedLiabilitiesCurrentAndNoncurrent
|
700000 | USD |
CY2016Q4 | us-gaap |
Accrued Liabilities Current And Noncurrent
AccruedLiabilitiesCurrentAndNoncurrent
|
2200000 | USD |
CY2017Q4 | us-gaap |
Prepaid Expense Current And Noncurrent
PrepaidExpenseCurrentAndNoncurrent
|
46000 | USD |
CY2016Q4 | us-gaap |
Prepaid Expense Current And Noncurrent
PrepaidExpenseCurrentAndNoncurrent
|
1700000 | USD |
CY2017 | us-gaap |
Current State And Local Tax Expense Benefit
CurrentStateAndLocalTaxExpenseBenefit
|
-613000 | USD |
CY2016 | us-gaap |
Current State And Local Tax Expense Benefit
CurrentStateAndLocalTaxExpenseBenefit
|
-1101000 | USD |
CY2017 | us-gaap |
Tax Adjustments Settlements And Unusual Provisions
TaxAdjustmentsSettlementsAndUnusualProvisions
|
-2000 | USD |
CY2016 | us-gaap |
Tax Adjustments Settlements And Unusual Provisions
TaxAdjustmentsSettlementsAndUnusualProvisions
|
-431000 | USD |
CY2017 | us-gaap |
Income Tax Reconciliation Nondeductible Expense Meals And Entertainment
IncomeTaxReconciliationNondeductibleExpenseMealsAndEntertainment
|
10000 | USD |
CY2016 | us-gaap |
Income Tax Reconciliation Nondeductible Expense Meals And Entertainment
IncomeTaxReconciliationNondeductibleExpenseMealsAndEntertainment
|
10000 | USD |
CY2017 | us-gaap |
Income Tax Reconciliation Nondeductible Expense Share Based Compensation Cost
IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost
|
502000 | USD |
CY2016 | us-gaap |
Income Tax Reconciliation Nondeductible Expense Share Based Compensation Cost
IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost
|
574000 | USD |
CY2017 | us-gaap |
Income Tax Reconciliation Other Adjustments
IncomeTaxReconciliationOtherAdjustments
|
-4076000 | USD |
CY2016 | us-gaap |
Income Tax Reconciliation Other Adjustments
IncomeTaxReconciliationOtherAdjustments
|
-4332000 | USD |
CY2017 | us-gaap |
Income Tax Reconciliation Change In Enacted Tax Rate
IncomeTaxReconciliationChangeInEnactedTaxRate
|
21555000 | USD |
CY2016 | us-gaap |
Income Tax Reconciliation Change In Enacted Tax Rate
IncomeTaxReconciliationChangeInEnactedTaxRate
|
0 | USD |
CY2017 | us-gaap |
Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
|
12109000 | USD |
CY2016 | us-gaap |
Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
|
-14733000 | USD |
CY2017 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
0 | USD |
CY2016 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
0 | USD |
CY2017Q4 | syn |
Deferred Tax Assets Stocks Issued For Services
DeferredTaxAssetsStocksIssuedForServices
|
1730000 | USD |
CY2016Q4 | syn |
Deferred Tax Assets Stocks Issued For Services
DeferredTaxAssetsStocksIssuedForServices
|
1861000 | USD |
CY2017Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits
|
164000 | USD |
CY2016Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits
|
119000 | USD |
CY2017Q4 | syn |
Deferred Tax Assets Stock Issued For Acquisition Of Program
DeferredTaxAssetsStockIssuedForAcquisitionOfProgram
|
1202000 | USD |
CY2016Q4 | syn |
Deferred Tax Assets Stock Issued Forlicense Agreement
DeferredTaxAssetsStockIssuedForlicenseAgreement
|
3147000 | USD |
CY2017Q4 | syn |
Deferred Tax Assets Stock Issued For Milestone Payment
DeferredTaxAssetsStockIssuedForMilestonePayment
|
301000 | USD |
CY2016Q4 | syn |
Deferred Tax Assets Stock Issued For Milestone Payment
DeferredTaxAssetsStockIssuedForMilestonePayment
|
478000 | USD |
CY2017Q4 | syn |
Deferred Tax Assets Tax Deferred Expense Amortizable License Fee
DeferredTaxAssetsTaxDeferredExpenseAmortizableLicenseFee
|
6000 | USD |
CY2016Q4 | syn |
Deferred Tax Assets Tax Deferred Expense Amortizable License Fee
DeferredTaxAssetsTaxDeferredExpenseAmortizableLicenseFee
|
9000 | USD |
CY2017Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
40248000 | USD |
CY2016Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
50517000 | USD |
CY2017Q4 | us-gaap |
Deferred Tax Assets Gross
DeferredTaxAssetsGross
|
45598000 | USD |
CY2016Q4 | us-gaap |
Deferred Tax Assets Gross
DeferredTaxAssetsGross
|
57707000 | USD |
CY2017Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
45598000 | USD |
CY2016Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
57707000 | USD |
CY2017Q4 | us-gaap |
Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
|
0 | USD |
CY2016Q4 | us-gaap |
Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
|
0 | USD |
CY2017 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.34 | pure |
CY2017 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.0396 | pure |
CY2017 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Enacted Tax Rate
EffectiveIncomeTaxRateReconciliationChangeInEnactedTaxRate
|
0.3796 | pure |
CY2016 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.34 | pure |
CY2016 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.0396 | pure |
CY2016 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Enacted Tax Rate
EffectiveIncomeTaxRateReconciliationChangeInEnactedTaxRate
|
0.3796 | pure |
CY2017Q4 | us-gaap |
Operating Loss Carryforwards
OperatingLossCarryforwards
|
156400000 | USD |
CY2017 | syn |
Operating Loss Carryforwards Expire Date
OperatingLossCarryforwardsExpireDate
|
2037 | |
CY2017Q4 | us-gaap |
Prepaid Insurance
PrepaidInsurance
|
351000 | USD |
CY2016Q4 | us-gaap |
Prepaid Insurance
PrepaidInsurance
|
358000 | USD |
CY2017Q4 | us-gaap |
Operating Leases Future Minimum Payments Due Current
OperatingLeasesFutureMinimumPaymentsDueCurrent
|
292000 | USD |
CY2017Q4 | us-gaap |
Other Prepaid Expense Current
OtherPrepaidExpenseCurrent
|
290000 | USD |
CY2016Q4 | us-gaap |
Other Prepaid Expense Current
OtherPrepaidExpenseCurrent
|
185000 | USD |
CY2017Q4 | us-gaap |
Operating Leases Future Minimum Payments Due In Two Years
OperatingLeasesFutureMinimumPaymentsDueInTwoYears
|
300000 | USD |
CY2017Q4 | us-gaap |
Prepaid Expense Current
PrepaidExpenseCurrent
|
94000 | USD |
CY2016Q4 | us-gaap |
Prepaid Expense Current
PrepaidExpenseCurrent
|
295000 | USD |
CY2017Q4 | us-gaap |
Operating Leases Future Minimum Payments Due In Three Years
OperatingLeasesFutureMinimumPaymentsDueInThreeYears
|
309000 | USD |
CY2017Q4 | us-gaap |
Other Receivables Net Current
OtherReceivablesNetCurrent
|
46000 | USD |
CY2016Q4 | us-gaap |
Other Receivables Net Current
OtherReceivablesNetCurrent
|
0 | USD |
CY2017Q4 | us-gaap |
Operating Leases Future Minimum Payments Due In Four Years
OperatingLeasesFutureMinimumPaymentsDueInFourYears
|
321000 | USD |
CY2017Q4 | syn |
Prepaid Clinical Research Organizations Expense Current
PrepaidClinicalResearchOrganizationsExpenseCurrent
|
46000 | USD |
CY2016Q4 | syn |
Prepaid Clinical Research Organizations Expense Current
PrepaidClinicalResearchOrganizationsExpenseCurrent
|
1677000 | USD |
CY2017Q4 | us-gaap |
Operating Leases Future Minimum Payments Due In Five Years
OperatingLeasesFutureMinimumPaymentsDueInFiveYears
|
192000 | USD |
CY2017Q4 | us-gaap |
Operating Leases Future Minimum Payments Due
OperatingLeasesFutureMinimumPaymentsDue
|
1414000 | USD |
CY2017Q4 | us-gaap |
Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
|
1301000 | USD |
CY2016Q4 | us-gaap |
Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
|
1091000 | USD |
CY2017Q4 | us-gaap |
Pension And Other Postretirement And Postemployment Benefit Plans Liabilities Current
PensionAndOtherPostretirementAndPostemploymentBenefitPlansLiabilitiesCurrent
|
590000 | USD |
CY2016Q4 | us-gaap |
Pension And Other Postretirement And Postemployment Benefit Plans Liabilities Current
PensionAndOtherPostretirementAndPostemploymentBenefitPlansLiabilitiesCurrent
|
52000 | USD |
CY2017 | us-gaap |
Proceeds From Repurchase Of Equity
ProceedsFromRepurchaseOfEquity
|
3000000 | USD |
CY2017Q4 | syn |
Exchange Percentage Of Unregistered Common Stock
ExchangePercentageOfUnregisteredCommonStock
|
0.5 | pure |
CY2017 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
|
0 | pure |
CY2016 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
|
0 | pure |
CY2015 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
|
0 | pure |
CY2016 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1
|
P7Y | |
CY2017Q4 | us-gaap |
Equity Method Investment Ownership Percentage
EquityMethodInvestmentOwnershipPercentage
|
0.885 | pure |
CY2017Q4 | us-gaap |
Minority Interest Ownership Percentage By Parent
MinorityInterestOwnershipPercentageByParent
|
0.115 | pure |
CY2015Q4 | syn |
Warrant Liabilities
WarrantLiabilities
|
10566000 | USD |
CY2016 | syn |
Issuance Of Warrants
IssuanceOfWarrants
|
15667000 | USD |
CY2015Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber
|
7908899 | shares |
CY2016 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod
|
50000000 | shares |
CY2017 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod
|
0 | shares |
CY2016 | syn |
Share Based Compensation Arrangement By Share Based Payment Award Other Than Options Exercises In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOtherThanOptionsExercisesInPeriod
|
0 | shares |
CY2017 | syn |
Share Based Compensation Arrangement By Share Based Payment Award Other Than Options Exercises In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOtherThanOptionsExercisesInPeriod
|
0 | shares |
CY2016 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeited In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod
|
567257 | shares |
CY2017 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeited In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod
|
25311834 | shares |
CY2016Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber
|
57341642 | shares |
CY2017Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber
|
32029809 | shares |
CY2016Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
|
1.60 | |
CY2017Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
|
1.50 | |
CY2017 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeitures Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue
|
1.72 | |
CY2016 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeitures Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue
|
2.35 | |
CY2017 | syn |
Share Based Compensation Arrangement By Share Based Payment Award Other Than Options Exercises In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOtherThanOptionsExercisesInPeriodWeightedAverageGrantDateFairValue
|
0 | |
CY2016 | syn |
Share Based Compensation Arrangement By Share Based Payment Award Other Than Options Exercises In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOtherThanOptionsExercisesInPeriodWeightedAverageGrantDateFairValue
|
0 | |
CY2016 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
1.58 | |
CY2017 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
0 | |
CY2015Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
|
1.79 | |
CY2017Q4 | us-gaap |
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Stock Options
EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions
|
2900000 | USD |
CY2017 | us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
166000 | USD |
CY2016 | us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
814000 | USD |
CY2015 | us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
41000 | USD |
CY2017Q4 | us-gaap |
Dividends Payable Current
DividendsPayableCurrent
|
73000 | USD |
CY2016Q4 | us-gaap |
Proceeds From Issuance Or Sale Of Equity
ProceedsFromIssuanceOrSaleOfEquity
|
23300000 | USD |
CY2015Q4 | us-gaap |
Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
|
15003000 | USD |
CY2016Q4 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
300000 | USD |
CY2017 | us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
0.21 | pure |
CY2017 | syn |
Options To Be Received Common Stock Shares
OptionsToBeReceivedCommonStockShares
|
2000000 | shares |
CY2016 | us-gaap |
Payments To Acquire In Process Research And Development
PaymentsToAcquireInProcessResearchAndDevelopment
|
643000 | USD |
CY2015 | us-gaap |
Payments To Acquire In Process Research And Development
PaymentsToAcquireInProcessResearchAndDevelopment
|
424000 | USD |
CY2017 | us-gaap |
Line Of Credit Facility Periodic Payment Interest
LineOfCreditFacilityPeriodicPaymentInterest
|
381150 | USD |
CY2012Q1 | us-gaap |
Officers Compensation
OfficersCompensation
|
348000 | USD |
CY2014Q2 | us-gaap |
Officers Compensation
OfficersCompensation
|
385000 | USD |
CY2015 | us-gaap |
Officers Compensation
OfficersCompensation
|
385000 | USD |
CY2016Q4 | syn |
Operating Annual Lease Payments
OperatingAnnualLeasePayments
|
285843 | USD |
CY2017 | us-gaap |
Lease And Rental Expense
LeaseAndRentalExpense
|
199000 | USD |
CY2016 | us-gaap |
Lease And Rental Expense
LeaseAndRentalExpense
|
145000 | USD |
CY2015 | us-gaap |
Lease And Rental Expense
LeaseAndRentalExpense
|
108000 | USD |
CY2017Q4 | us-gaap |
Payments For Fees
PaymentsForFees
|
5500000 | USD |
CY2016 | us-gaap |
Proceeds From Repurchase Of Equity
ProceedsFromRepurchaseOfEquity
|
3000000 | USD |
CY2017Q4 | us-gaap |
Share Price
SharePrice
|
0.51 | |
CY2016Q4 | us-gaap |
Share Price
SharePrice
|
0.76 | |
CY2016Q4 | us-gaap |
Share Price
SharePrice
|
1.75 | |
CY2017 | us-gaap |
Fair Value Assumptions Expected Dividend Rate
FairValueAssumptionsExpectedDividendRate
|
0 | pure |
CY2016 | us-gaap |
Fair Value Assumptions Expected Dividend Rate
FairValueAssumptionsExpectedDividendRate
|
0 | pure |
CY2016Q4 | us-gaap |
Fair Value Assumptions Expected Dividend Rate
FairValueAssumptionsExpectedDividendRate
|
0 | pure |
CY2017 | us-gaap |
Fair Value Assumptions Expected Volatility Rate
FairValueAssumptionsExpectedVolatilityRate
|
0.8 | pure |
CY2016 | us-gaap |
Fair Value Assumptions Expected Volatility Rate
FairValueAssumptionsExpectedVolatilityRate
|
0.95 | pure |
CY2016Q4 | us-gaap |
Fair Value Assumptions Expected Volatility Rate
FairValueAssumptionsExpectedVolatilityRate
|
0.95 | pure |
CY2017 | us-gaap |
Fair Value Assumptions Risk Free Interest Rate
FairValueAssumptionsRiskFreeInterestRate
|
0.0186 | pure |
CY2016 | us-gaap |
Fair Value Assumptions Risk Free Interest Rate
FairValueAssumptionsRiskFreeInterestRate
|
0.0141 | pure |
CY2016Q4 | us-gaap |
Fair Value Assumptions Risk Free Interest Rate
FairValueAssumptionsRiskFreeInterestRate
|
0.0139 | pure |
CY2017 | us-gaap |
Fair Value Assumptions Expected Term
FairValueAssumptionsExpectedTerm
|
P1Y9M14D | |
CY2016 | us-gaap |
Fair Value Assumptions Expected Term
FairValueAssumptionsExpectedTerm
|
P2Y9M14D | |
CY2016Q4 | us-gaap |
Fair Value Assumptions Expected Term
FairValueAssumptionsExpectedTerm
|
P5Y | |
CY2017Q4 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.35 | pure |