2017 Form 10-K Financial Statement

#000114420418010286 Filed on February 22, 2018

View on sec.gov

Income Statement

Concept 2017 2016 Q4 2016 Q3
Revenue $0.00 $0.00 $0.00
YoY Change
Cost Of Revenue
YoY Change
Gross Profit
YoY Change
Gross Profit Margin
Selling, General & Admin $7.467M $3.480M $2.100M
YoY Change -26.38% 37.01% 31.25%
% of Gross Profit
Research & Development $18.78M $6.730M $7.061M
YoY Change -35.47% -24.04% -29.71%
% of Gross Profit
Depreciation & Amortization $245.0K $50.00K $50.00K
YoY Change 56.05% 66.67% 150.0%
% of Gross Profit
Operating Expenses $26.25M $10.20M $9.156M
YoY Change -33.12% -10.45% -21.41%
Operating Profit -$26.25M -$9.156M
YoY Change -33.12% -21.41%
Interest Expense $21.00K $0.00 $0.00
YoY Change -43.24%
% of Operating Profit
Other Income/Expense, Net $10.76M $7.730M $667.0K
YoY Change -6.03% 7630.0% -83.9%
Pretax Income -$15.49M -$10.20M -$9.156M
YoY Change -44.28% -10.44% -21.41%
Income Tax $0.00
% Of Pretax Income
Net Earnings -$15.17M -$2.472M -$8.489M
YoY Change -44.33% -78.12% 13.08%
Net Earnings / Revenue
Basic Earnings Per Share -$0.02 -$0.09
Diluted Earnings Per Share -$42.71M -$0.02 -$0.09
COMMON SHARES
Basic Shares Outstanding 103.8M shares 91.44M shares
Diluted Shares Outstanding 103.8M shares 91.44M shares

Balance Sheet

Concept 2017 2016 Q4 2016 Q3
SHORT-TERM ASSETS
Cash & Short-Term Investments $17.12M $19.06M $4.550M
YoY Change -10.18% -8.45% -85.7%
Cash & Equivalents $17.12M $19.06M $4.549M
Short-Term Investments
Other Short-Term Assets $827.0K $185.0K $294.0K
YoY Change -67.12% -97.15%
Inventory
Prepaid Expenses $295.0K
Receivables
Other Receivables $0.00
Total Short-Term Assets $17.94M $21.57M $7.640M
YoY Change -16.82% -28.9% -81.87%
LONG-TERM ASSETS
Property, Plant & Equipment $872.0K $905.0K $580.0K
YoY Change -3.65% 83.2% 20.08%
Goodwill
YoY Change
Intangibles
YoY Change
Long-Term Investments
YoY Change
Other Assets $23.00K $20.00K $30.00K
YoY Change 0.0% 100.0% 200.0%
Total Long-Term Assets $895.0K $928.0K $610.0K
YoY Change -3.56% 80.9% 22.74%
TOTAL ASSETS
Total Short-Term Assets $17.94M $21.57M $7.640M
Total Long-Term Assets $895.0K $928.0K $610.0K
Total Assets $18.84M $22.50M $8.250M
YoY Change -16.27% -27.07% -80.65%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable $2.020M $1.993M $4.240M
YoY Change 1.35% -54.81% -29.64%
Accrued Expenses $3.600M $2.627M $2.830M
YoY Change 22.45% 784.51% 1059.84%
Deferred Revenue
YoY Change
Short-Term Debt $0.00 $0.00 $0.00
YoY Change
Long-Term Debt Due
YoY Change
Total Short-Term Liabilities $9.793M $19.76M $14.01M
YoY Change -50.43% 26.85% -19.02%
LONG-TERM LIABILITIES
Long-Term Debt $0.00 $0.00 $0.00
YoY Change
Other Long-Term Liabilities $402.0K $490.0K $210.0K
YoY Change -18.29% 81.48% 5.0%
Total Long-Term Liabilities $402.0K $490.0K $210.0K
YoY Change -18.29% 81.48% 5.0%
TOTAL LIABILITIES
Total Short-Term Liabilities $9.793M $19.76M $14.01M
Total Long-Term Liabilities $402.0K $490.0K $210.0K
Total Liabilities $8.281M $20.25M $12.72M
YoY Change -55.6% 27.82% -27.31%
SHAREHOLDERS EQUITY
Retained Earnings -$172.0M
YoY Change
Common Stock $175.9M
YoY Change
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity $10.56M $3.845M -$4.480M
YoY Change
Total Liabilities & Shareholders Equity $18.84M $22.50M $8.250M
YoY Change -16.27% -27.07% -80.65%

Cashflow Statement

Concept 2017 2016 Q4 2016 Q3
OPERATING ACTIVITIES
Net Income -$15.17M -$2.472M -$8.489M
YoY Change -44.33% -78.12% 13.08%
Depreciation, Depletion And Amortization $245.0K $50.00K $50.00K
YoY Change 56.05% 66.67% 150.0%
Cash From Operating Activities -$20.20M -$10.38M -$5.990M
YoY Change -27.59% -5.38% -60.62%
INVESTING ACTIVITIES
Capital Expenditures $212.0K -$370.0K -$150.0K
YoY Change -62.74% 825.0% -62.5%
Acquisitions
YoY Change
Other Investing Activities
YoY Change
Cash From Investing Activities -$212.0K -$370.0K -$150.0K
YoY Change -62.74% 825.0% -62.5%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net $0.00 $300.0K
YoY Change -100.0%
Debt Paid & Issued, Net
YoY Change
Cash From Financing Activities 18.48M 25.26M 640.0K
YoY Change -30.82% 126200.0% -98.5%
NET CHANGE
Cash From Operating Activities -20.20M -10.38M -5.990M
Cash From Investing Activities -212.0K -370.0K -150.0K
Cash From Financing Activities 18.48M 25.26M 640.0K
Net Change In Cash -1.939M 14.51M -5.500M
YoY Change 9.98% -232.03% -120.33%
FREE CASH FLOW
Cash From Operating Activities -$20.20M -$10.38M -$5.990M
Capital Expenditures $212.0K -$370.0K -$150.0K
Free Cash Flow -$20.42M -$10.01M -$5.840M
YoY Change -28.29% -8.42% -60.57%

Facts In Submission

Frame Concept Type Concept / XBRL Key Value Unit
CY2015 us-gaap Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
46000000 USD
CY2016Q4 syn Accrued Clinical Consulting Services
AccruedClinicalConsultingServices
2211000 USD
CY2017Q4 syn Accrued Manufacturing Costs
AccruedManufacturingCosts
661000 USD
CY2017 dei Entity Well Known Seasoned Issuer
EntityWellKnownSeasonedIssuer
No
CY2017 dei Entity Voluntary Filers
EntityVoluntaryFilers
No
CY2017 dei Entity Current Reporting Status
EntityCurrentReportingStatus
Yes
CY2017 dei Entity Filer Category
EntityFilerCategory
Accelerated Filer
CY2017Q2 dei Entity Public Float
EntityPublicFloat
64400000 USD
CY2017 dei Trading Symbol
TradingSymbol
SYN
CY2018Q1 dei Entity Common Stock Shares Outstanding
EntityCommonStockSharesOutstanding
128566886 shares
CY2016Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
19055000 USD
CY2016Q4 us-gaap Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
2515000 USD
CY2016Q4 us-gaap Assets Current
AssetsCurrent
21570000 USD
CY2016Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
905000 USD
CY2016Q4 syn Deposits And Other Assets Noncurrent
DepositsAndOtherAssetsNoncurrent
23000 USD
CY2016Q4 us-gaap Assets
Assets
22498000 USD
CY2016Q4 us-gaap Accounts Payable Current
AccountsPayableCurrent
1993000 USD
CY2016Q4 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
2627000 USD
CY2016Q4 us-gaap Liabilities Current
LiabilitiesCurrent
19757000 USD
CY2016Q4 us-gaap Liabilities
Liabilities
20249000 USD
CY2017Q4 us-gaap Common Stock Value
CommonStockValue
129000 USD
CY2016Q4 us-gaap Common Stock Value
CommonStockValue
117000 USD
CY2017Q4 us-gaap Additional Paid In Capital Common Stock
AdditionalPaidInCapitalCommonStock
192545000 USD
CY2016Q4 us-gaap Additional Paid In Capital Common Stock
AdditionalPaidInCapitalCommonStock
175762000 USD
CY2017Q4 us-gaap Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
-194170000 USD
CY2016Q4 us-gaap Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
-172034000 USD
CY2017Q4 us-gaap Stockholders Equity
StockholdersEquity
-1496000 USD
CY2016Q4 us-gaap Stockholders Equity
StockholdersEquity
3845000 USD
CY2017Q4 us-gaap Minority Interest
MinorityInterest
-1914000 USD
CY2016Q4 us-gaap Minority Interest
MinorityInterest
-1596000 USD
CY2017Q4 us-gaap Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
-3410000 USD
CY2016Q4 us-gaap Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
2249000 USD
CY2017Q4 us-gaap Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
18838000 USD
CY2016Q4 us-gaap Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
22498000 USD
CY2017Q4 syn Warrant Liabilities
WarrantLiabilities
4083000 USD
CY2016Q4 syn Warrant Liabilities
WarrantLiabilities
14821000 USD
CY2017Q4 us-gaap Accrued Employee Benefits Current
AccruedEmployeeBenefitsCurrent
2074000 USD
CY2016Q4 us-gaap Accrued Employee Benefits Current
AccruedEmployeeBenefitsCurrent
313000 USD
CY2017Q4 us-gaap Deferred Rent Credit Current
DeferredRentCreditCurrent
90000 USD
CY2016Q4 us-gaap Deferred Rent Credit Current
DeferredRentCreditCurrent
3000 USD
CY2017Q4 us-gaap Deferred Rent Credit Noncurrent
DeferredRentCreditNoncurrent
402000 USD
CY2016Q4 us-gaap Deferred Rent Credit Noncurrent
DeferredRentCreditNoncurrent
492000 USD
CY2016 us-gaap Operating Expenses
OperatingExpenses
39252000 USD
CY2016 us-gaap Operating Income Loss
OperatingIncomeLoss
-39252000 USD
CY2016 us-gaap Investment Income Interest
InvestmentIncomeInterest
37000 USD
CY2016 us-gaap Nonoperating Income Expense
NonoperatingIncomeExpense
11449000 USD
CY2016 us-gaap Net Income Loss Attributable To Noncontrolling Interest
NetIncomeLossAttributableToNoncontrollingInterest
-548000 USD
CY2016 us-gaap Net Income Loss
NetIncomeLoss
-27255000 USD
CY2016 us-gaap Fair Value Adjustment Of Warrants
FairValueAdjustmentOfWarrants
-11412000 USD
CY2015 us-gaap General And Administrative Expense
GeneralAndAdministrativeExpense
8074000 USD
CY2015 us-gaap Operating Income Loss
OperatingIncomeLoss
-40980000 USD
CY2015 us-gaap Net Income Loss Attributable To Noncontrolling Interest
NetIncomeLossAttributableToNoncontrollingInterest
-1048000 USD
CY2015 us-gaap Net Income Loss
NetIncomeLoss
-43737000 USD
CY2017 us-gaap Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
-0.18
CY2016 us-gaap Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
-0.29
CY2015 us-gaap Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
-0.54
CY2017 us-gaap Preferred Stock Dividends Income Statement Impact
PreferredStockDividendsIncomeStatementImpact
6962000 USD
CY2016 us-gaap Preferred Stock Dividends Income Statement Impact
PreferredStockDividendsIncomeStatementImpact
0 USD
CY2015 us-gaap Preferred Stock Dividends Income Statement Impact
PreferredStockDividendsIncomeStatementImpact
0 USD
CY2017 us-gaap Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
-22136000 USD
CY2016 us-gaap Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
-27255000 USD
CY2015 us-gaap Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
-43737000 USD
CY2017 us-gaap Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
124366059 shares
CY2016 us-gaap Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
94290436 shares
CY2015 us-gaap Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
80705692 shares
CY2016 us-gaap Share Based Compensation
ShareBasedCompensation
4009000 USD
CY2016 us-gaap Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
-7004000 USD
CY2016 syn Increase Decrease In Deposits And Other Assets
IncreaseDecreaseInDepositsAndOtherAssets
9000 USD
CY2016 us-gaap Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
-2420000 USD
CY2016 us-gaap Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
2330000 USD
CY2016 us-gaap Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
-27901000 USD
CY2016 us-gaap Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
569000 USD
CY2016 us-gaap Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
26707000 USD
CY2016 us-gaap Cash Period Increase Decrease
CashPeriodIncreaseDecrease
-1763000 USD
CY2015Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
20818000 USD
CY2016 us-gaap Increase Decrease In Deferred Compensation
IncreaseDecreaseInDeferredCompensation
207000 USD
CY2017 us-gaap Share Based Compensation
ShareBasedCompensation
3409000 USD
CY2017 us-gaap Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
-1688000 USD
CY2017 syn Increase Decrease In Deposits And Other Assets
IncreaseDecreaseInDepositsAndOtherAssets
0 USD
CY2017 us-gaap Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
27000 USD
CY2017 us-gaap Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
-20204000 USD
CY2017 us-gaap Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
212000 USD
CY2017 us-gaap Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
-212000 USD
CY2017 syn Proceeds From Issuance Of Common Stock For Stock Option And Warrants Exercises
ProceedsFromIssuanceOfCommonStockForStockOptionAndWarrantsExercises
166000 USD
CY2017 us-gaap Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
18477000 USD
CY2017 us-gaap Cash Period Increase Decrease
CashPeriodIncreaseDecrease
-1939000 USD
CY2017 us-gaap Increase Decrease In Employee Related Liabilities
IncreaseDecreaseInEmployeeRelatedLiabilities
1761000 USD
CY2017 us-gaap Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
-1101000 USD
CY2017 us-gaap Increase Decrease In Deferred Compensation
IncreaseDecreaseInDeferredCompensation
-3000 USD
CY2016 us-gaap Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
157000 USD
CY2017 us-gaap Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
245000 USD
CY2017 us-gaap Proceeds From Issuance Or Sale Of Equity
ProceedsFromIssuanceOrSaleOfEquity
6358000 USD
CY2016 us-gaap Proceeds From Issuance Or Sale Of Equity
ProceedsFromIssuanceOrSaleOfEquity
1509000 USD
CY2017 us-gaap Proceeds From Issuance Of Convertible Preferred Stock
ProceedsFromIssuanceOfConvertiblePreferredStock
11953000 USD
CY2016 us-gaap Proceeds From Issuance Of Convertible Preferred Stock
ProceedsFromIssuanceOfConvertiblePreferredStock
0 USD
CY2017Q4 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
429000 USD
CY2016Q4 syn Accrued Vendor Payments
AccruedVendorPayments
400000 USD
CY2017Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
14000 USD
CY2016Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
2000 USD
CY2017 syn Issue Of Stock For Exclusive Channel Collaboration Agreement
IssueOfStockForExclusiveChannelCollaborationAgreement
0 USD
CY2016 syn Issue Of Stock For Exclusive Channel Collaboration Agreement
IssueOfStockForExclusiveChannelCollaborationAgreement
0 USD
CY2015 syn Issue Of Stock For Exclusive Channel Collaboration Agreement
IssueOfStockForExclusiveChannelCollaborationAgreement
-3000000 USD
CY2015 us-gaap Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
72000 USD
CY2015 us-gaap Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
7971000 USD
CY2016Q4 syn Accrued Manufacturing Costs
AccruedManufacturingCosts
14000 USD
CY2017 us-gaap Dividends Preferred Stock
DividendsPreferredStock
73000 USD
CY2015 us-gaap Share Based Compensation
ShareBasedCompensation
3198000 USD
CY2017 syn Stock Issued For Milestone Payments
StockIssuedForMilestonePayments
0 USD
CY2016 syn Stock Issued For Milestone Payments
StockIssuedForMilestonePayments
0 USD
CY2015 syn Stock Issued For Milestone Payments
StockIssuedForMilestonePayments
-1350000 USD
CY2017Q4 us-gaap Accrued Bonuses Current
AccruedBonusesCurrent
1283000 USD
CY2016Q4 us-gaap Accrued Bonuses Current
AccruedBonusesCurrent
0 USD
CY2017Q4 us-gaap Accrued Vacation Current
AccruedVacationCurrent
201000 USD
CY2016Q4 us-gaap Accrued Vacation Current
AccruedVacationCurrent
261000 USD
CY2017Q4 us-gaap Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
2074000 USD
CY2016Q4 us-gaap Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
313000 USD
CY2017Q4 us-gaap Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
0.001
CY2016Q4 us-gaap Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
0.001
CY2017Q4 us-gaap Common Stock Shares Authorized
CommonStockSharesAuthorized
350000000 shares
CY2016Q4 us-gaap Common Stock Shares Authorized
CommonStockSharesAuthorized
350000000 shares
CY2017Q4 us-gaap Common Stock Shares Issued
CommonStockSharesIssued
128648365 shares
CY2016Q4 us-gaap Common Stock Shares Issued
CommonStockSharesIssued
117254196 shares
CY2017Q4 us-gaap Common Stock Shares Outstanding
CommonStockSharesOutstanding
128566886 shares
CY2016Q4 us-gaap Common Stock Shares Outstanding
CommonStockSharesOutstanding
117172714 shares
CY2014Q4 us-gaap Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
9556000 USD
CY2015 us-gaap Adjustments To Additional Paid In Capital Share Based Compensation Stock Options Requisite Service Period Recognition
AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationStockOptionsRequisiteServicePeriodRecognition
3198000 USD
CY2016 us-gaap Adjustments To Additional Paid In Capital Share Based Compensation Stock Options Requisite Service Period Recognition
AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationStockOptionsRequisiteServicePeriodRecognition
4009000 USD
CY2017 us-gaap Adjustments To Additional Paid In Capital Share Based Compensation Stock Options Requisite Service Period Recognition
AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationStockOptionsRequisiteServicePeriodRecognition
3409000 USD
CY2015 us-gaap Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
42643000 USD
CY2016 us-gaap Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
24384000 USD
CY2015 syn Stock Issued During Period Valuemilestone Payment
StockIssuedDuringPeriodValuemilestonePayment
1350000 USD
CY2015 syn Stock Issued During Period Value For Exclusive Channel Collaboration Agreement
StockIssuedDuringPeriodValueForExclusiveChannelCollaborationAgreement
3000000 USD
CY2015 us-gaap Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
41000 USD
CY2016 us-gaap Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
814000 USD
CY2017 us-gaap Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
166000 USD
CY2015 syn Issuance Value Of Common Stock Upon Exercise Of Warrants
IssuanceValueOfCommonStockUponExerciseOfWarrants
0 USD
CY2016 us-gaap Adjustments To Additional Paid In Capital Warrant Issued
AdjustmentsToAdditionalPaidInCapitalWarrantIssued
15667000 USD
CY2016 syn Stock Issued During Period At Market Offering Value
StockIssuedDuringPeriodAtMarketOfferingValue
1509000 USD
CY2017 syn Stock Issued During Period At Market Offering Value
StockIssuedDuringPeriodAtMarketOfferingValue
6358000 USD
CY2017 syn Adjustments To Additional Paid In Capital Convertible Preferred Stock With Conversion Feature
AdjustmentsToAdditionalPaidInCapitalConvertiblePreferredStockWithConversionFeature
0 USD
CY2017 us-gaap Adjustments To Additional Paid In Capital Stock Issued Issuance Costs
AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts
27000 USD
CY2015 syn Increase Decrease In Deposits And Other Assets
IncreaseDecreaseInDepositsAndOtherAssets
8000 USD
CY2015 us-gaap Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
3417000 USD
CY2015 us-gaap Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
-1001000 USD
CY2015 us-gaap Increase Decrease In Employee Related Liabilities
IncreaseDecreaseInEmployeeRelatedLiabilities
-261000 USD
CY2015 us-gaap Increase Decrease In Deferred Compensation
IncreaseDecreaseInDeferredCompensation
288000 USD
CY2015 us-gaap Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
-38890000 USD
CY2015 us-gaap Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
501000 USD
CY2015 us-gaap Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
-501000 USD
CY2015 us-gaap Proceeds From Issuance Of Convertible Preferred Stock
ProceedsFromIssuanceOfConvertiblePreferredStock
0 USD
CY2015 syn Proceeds From Issuance Of Common Stock For Stock Option And Warrants Exercises
ProceedsFromIssuanceOfCommonStockForStockOptionAndWarrantsExercises
41000 USD
CY2015 us-gaap Proceeds From Issuance Or Sale Of Equity
ProceedsFromIssuanceOrSaleOfEquity
0 USD
CY2017 us-gaap Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
0 USD
CY2016 us-gaap Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
25000000 USD
CY2017 syn Direct Offering Cost
DirectOfferingCost
0 USD
CY2016 syn Direct Offering Cost
DirectOfferingCost
616000 USD
CY2015 syn Direct Offering Cost
DirectOfferingCost
3357000 USD
CY2015 us-gaap Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
42684000 USD
CY2015 us-gaap Cash Period Increase Decrease
CashPeriodIncreaseDecrease
3293000 USD
CY2014Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
17525000 USD
CY2017Q1 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-8149000 USD
CY2017Q2 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-6475000 USD
CY2017Q3 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-5842000 USD
CY2017Q4 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-5783000 USD
CY2017Q1 us-gaap Net Income Loss
NetIncomeLoss
-3058000 USD
CY2017Q2 us-gaap Net Income Loss
NetIncomeLoss
-4315000 USD
CY2017Q3 us-gaap Net Income Loss
NetIncomeLoss
-10930000 USD
CY2017Q4 us-gaap Net Income Loss
NetIncomeLoss
2812000 USD
CY2017Q1 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.02
CY2017Q2 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.03
CY2017Q3 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.14
CY2017Q4 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
0.02
CY2017Q1 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.02
CY2017Q2 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.03
CY2017Q3 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.14
CY2017Q4 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
0.02
CY2017Q1 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
117447260 shares
CY2017Q2 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
123005220 shares
CY2017Q3 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
128279674 shares
CY2017Q4 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
128566883 shares
CY2017 us-gaap Use Of Estimates
UseOfEstimates
<div style="MARGIN: 0pt 0px; FONT: 10pt Times New Roman, Times, Serif "> <div style="CLEAR:both; FONT-FAMILY:Times New Roman;FONT-SIZE: 10pt;MARGIN: 0pt 0px; FONT: 10pt Times New Roman, Times, Serif" align="justify"></div> <div style="CLEAR:both; FONT-FAMILY:Times New Roman;FONT-SIZE: 10pt;MARGIN: 0pt 0px; FONT: 10pt Times New Roman, Times, Serif" align="justify"><b><i>Use of Estimates</i></b></div> <div style="CLEAR:both; FONT-FAMILY:Times New Roman;FONT-SIZE: 10pt;MARGIN: 0pt 0px; FONT: 10pt Times New Roman, Times, Serif" align="justify">&#160;</div> <div style="CLEAR:both; FONT-FAMILY:Times New Roman;FONT-SIZE: 10pt;MARGIN: 0pt 0px; FONT: 10pt Times New Roman, Times, Serif" align="justify">The preparation of consolidated financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect the amounts reported in the consolidated financial statements and accompanying notes. Such estimates and assumptions impact, among others, the following: the estimated useful lives for property and equipment, fair value of warrants, preferred stock and stock options granted for services or compensation, respectively, estimates of the probability and potential magnitude of contingent liabilities, and the valuation allowance for deferred tax assets due to continuing and expected future operating losses.</div> <div style="CLEAR:both; FONT-FAMILY:Times New Roman;FONT-SIZE: 10pt;MARGIN: 0pt 0px; FONT: 10pt Times New Roman, Times, Serif" align="justify">&#160;</div> <div style="CLEAR:both; FONT-FAMILY:Times New Roman;FONT-SIZE: 10pt;MARGIN: 0pt 0px; FONT: 10pt Times New Roman, Times, Serif" align="justify">Making estimates requires management to exercise significant judgment. It is at least reasonably possible that the estimate of the effect of a condition, situation or set of consolidated financial statements, which management considered in formulating its estimate could change in the near term due to one or more future confirming events. Accordingly, actual results could differ from those estimates.</div> </div><table border="0" style="width:100%; table-layout:fixed;" cellspacing="0" cellpadding="0"><tr><td></td></tr></table>
CY2017Q1 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
117447260 shares
CY2017Q2 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
123005220 shares
CY2017Q3 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
128279674 shares
CY2017Q4 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
150847262 shares
CY2016Q4 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.02
CY2016Q1 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
90826752 shares
CY2016Q2 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
91015733 shares
CY2016Q3 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
91441687 shares
CY2016Q4 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
103804308 shares
CY2016Q1 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
90826752 shares
CY2016Q2 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
93930540 shares
CY2016Q3 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
91441687 shares
CY2016Q1 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-10581000 USD
CY2016Q2 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-9311000 USD
CY2016Q3 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-9156000 USD
CY2016Q4 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-10204000 USD
CY2016Q1 us-gaap Net Income Loss
NetIncomeLoss
-11078000 USD
CY2016Q2 us-gaap Net Income Loss
NetIncomeLoss
-5764000 USD
CY2016Q3 us-gaap Net Income Loss
NetIncomeLoss
-8489000 USD
CY2016Q4 us-gaap Net Income Loss
NetIncomeLoss
-2472000 USD
CY2016Q1 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.12
CY2016Q2 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.06
CY2016Q3 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.09
CY2016Q4 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.02
CY2016Q1 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.12
CY2016Q2 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.10
CY2016Q3 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.09
CY2016Q4 us-gaap Equity Method Investment Ownership Percentage
EquityMethodInvestmentOwnershipPercentage
0.885 pure
CY2016Q4 us-gaap Minority Interest Ownership Percentage By Parent
MinorityInterestOwnershipPercentageByParent
0.115 pure
CY2017 us-gaap Current Federal Tax Expense Benefit
CurrentFederalTaxExpenseBenefit
-5267000 USD
CY2016 us-gaap Current Federal Tax Expense Benefit
CurrentFederalTaxExpenseBenefit
-9453000 USD
CY2017Q4 us-gaap Accrued Liabilities Current And Noncurrent
AccruedLiabilitiesCurrentAndNoncurrent
700000 USD
CY2016Q4 us-gaap Accrued Liabilities Current And Noncurrent
AccruedLiabilitiesCurrentAndNoncurrent
2200000 USD
CY2017Q4 us-gaap Prepaid Expense Current And Noncurrent
PrepaidExpenseCurrentAndNoncurrent
46000 USD
CY2016Q4 us-gaap Prepaid Expense Current And Noncurrent
PrepaidExpenseCurrentAndNoncurrent
1700000 USD
CY2017 us-gaap Current State And Local Tax Expense Benefit
CurrentStateAndLocalTaxExpenseBenefit
-613000 USD
CY2016 us-gaap Current State And Local Tax Expense Benefit
CurrentStateAndLocalTaxExpenseBenefit
-1101000 USD
CY2017 us-gaap Tax Adjustments Settlements And Unusual Provisions
TaxAdjustmentsSettlementsAndUnusualProvisions
-2000 USD
CY2016 us-gaap Tax Adjustments Settlements And Unusual Provisions
TaxAdjustmentsSettlementsAndUnusualProvisions
-431000 USD
CY2017 us-gaap Income Tax Reconciliation Nondeductible Expense Meals And Entertainment
IncomeTaxReconciliationNondeductibleExpenseMealsAndEntertainment
10000 USD
CY2016 us-gaap Income Tax Reconciliation Nondeductible Expense Meals And Entertainment
IncomeTaxReconciliationNondeductibleExpenseMealsAndEntertainment
10000 USD
CY2017 us-gaap Income Tax Reconciliation Nondeductible Expense Share Based Compensation Cost
IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost
502000 USD
CY2016 us-gaap Income Tax Reconciliation Nondeductible Expense Share Based Compensation Cost
IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost
574000 USD
CY2017 us-gaap Income Tax Reconciliation Other Adjustments
IncomeTaxReconciliationOtherAdjustments
-4076000 USD
CY2016 us-gaap Income Tax Reconciliation Other Adjustments
IncomeTaxReconciliationOtherAdjustments
-4332000 USD
CY2017 us-gaap Income Tax Reconciliation Change In Enacted Tax Rate
IncomeTaxReconciliationChangeInEnactedTaxRate
21555000 USD
CY2016 us-gaap Income Tax Reconciliation Change In Enacted Tax Rate
IncomeTaxReconciliationChangeInEnactedTaxRate
0 USD
CY2017 us-gaap Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
12109000 USD
CY2016 us-gaap Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
-14733000 USD
CY2017 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
0 USD
CY2016 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
0 USD
CY2017Q4 syn Deferred Tax Assets Stocks Issued For Services
DeferredTaxAssetsStocksIssuedForServices
1730000 USD
CY2016Q4 syn Deferred Tax Assets Stocks Issued For Services
DeferredTaxAssetsStocksIssuedForServices
1861000 USD
CY2017Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Compensation And Benefits
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits
164000 USD
CY2016Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Compensation And Benefits
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits
119000 USD
CY2017Q4 syn Deferred Tax Assets Stock Issued For Acquisition Of Program
DeferredTaxAssetsStockIssuedForAcquisitionOfProgram
1202000 USD
CY2016Q4 syn Deferred Tax Assets Stock Issued Forlicense Agreement
DeferredTaxAssetsStockIssuedForlicenseAgreement
3147000 USD
CY2017Q4 syn Deferred Tax Assets Stock Issued For Milestone Payment
DeferredTaxAssetsStockIssuedForMilestonePayment
301000 USD
CY2016Q4 syn Deferred Tax Assets Stock Issued For Milestone Payment
DeferredTaxAssetsStockIssuedForMilestonePayment
478000 USD
CY2017Q4 syn Deferred Tax Assets Tax Deferred Expense Amortizable License Fee
DeferredTaxAssetsTaxDeferredExpenseAmortizableLicenseFee
6000 USD
CY2016Q4 syn Deferred Tax Assets Tax Deferred Expense Amortizable License Fee
DeferredTaxAssetsTaxDeferredExpenseAmortizableLicenseFee
9000 USD
CY2017Q4 us-gaap Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
40248000 USD
CY2016Q4 us-gaap Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
50517000 USD
CY2017Q4 us-gaap Deferred Tax Assets Gross
DeferredTaxAssetsGross
45598000 USD
CY2016Q4 us-gaap Deferred Tax Assets Gross
DeferredTaxAssetsGross
57707000 USD
CY2017Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
45598000 USD
CY2016Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
57707000 USD
CY2017Q4 us-gaap Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
0 USD
CY2016Q4 us-gaap Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
0 USD
CY2017 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
0.34 pure
CY2017 us-gaap Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
0.0396 pure
CY2017 us-gaap Effective Income Tax Rate Reconciliation Change In Enacted Tax Rate
EffectiveIncomeTaxRateReconciliationChangeInEnactedTaxRate
0.3796 pure
CY2016 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
0.34 pure
CY2016 us-gaap Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
0.0396 pure
CY2016 us-gaap Effective Income Tax Rate Reconciliation Change In Enacted Tax Rate
EffectiveIncomeTaxRateReconciliationChangeInEnactedTaxRate
0.3796 pure
CY2017Q4 us-gaap Operating Loss Carryforwards
OperatingLossCarryforwards
156400000 USD
CY2017 syn Operating Loss Carryforwards Expire Date
OperatingLossCarryforwardsExpireDate
2037
CY2017Q4 us-gaap Prepaid Insurance
PrepaidInsurance
351000 USD
CY2016Q4 us-gaap Prepaid Insurance
PrepaidInsurance
358000 USD
CY2017Q4 us-gaap Operating Leases Future Minimum Payments Due Current
OperatingLeasesFutureMinimumPaymentsDueCurrent
292000 USD
CY2017Q4 us-gaap Other Prepaid Expense Current
OtherPrepaidExpenseCurrent
290000 USD
CY2016Q4 us-gaap Other Prepaid Expense Current
OtherPrepaidExpenseCurrent
185000 USD
CY2017Q4 us-gaap Operating Leases Future Minimum Payments Due In Two Years
OperatingLeasesFutureMinimumPaymentsDueInTwoYears
300000 USD
CY2017Q4 us-gaap Prepaid Expense Current
PrepaidExpenseCurrent
94000 USD
CY2016Q4 us-gaap Prepaid Expense Current
PrepaidExpenseCurrent
295000 USD
CY2017Q4 us-gaap Operating Leases Future Minimum Payments Due In Three Years
OperatingLeasesFutureMinimumPaymentsDueInThreeYears
309000 USD
CY2017Q4 us-gaap Other Receivables Net Current
OtherReceivablesNetCurrent
46000 USD
CY2016Q4 us-gaap Other Receivables Net Current
OtherReceivablesNetCurrent
0 USD
CY2017Q4 us-gaap Operating Leases Future Minimum Payments Due In Four Years
OperatingLeasesFutureMinimumPaymentsDueInFourYears
321000 USD
CY2017Q4 syn Prepaid Clinical Research Organizations Expense Current
PrepaidClinicalResearchOrganizationsExpenseCurrent
46000 USD
CY2016Q4 syn Prepaid Clinical Research Organizations Expense Current
PrepaidClinicalResearchOrganizationsExpenseCurrent
1677000 USD
CY2017Q4 us-gaap Operating Leases Future Minimum Payments Due In Five Years
OperatingLeasesFutureMinimumPaymentsDueInFiveYears
192000 USD
CY2017Q4 us-gaap Operating Leases Future Minimum Payments Due
OperatingLeasesFutureMinimumPaymentsDue
1414000 USD
CY2017Q4 us-gaap Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
1301000 USD
CY2016Q4 us-gaap Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
1091000 USD
CY2017Q4 us-gaap Pension And Other Postretirement And Postemployment Benefit Plans Liabilities Current
PensionAndOtherPostretirementAndPostemploymentBenefitPlansLiabilitiesCurrent
590000 USD
CY2016Q4 us-gaap Pension And Other Postretirement And Postemployment Benefit Plans Liabilities Current
PensionAndOtherPostretirementAndPostemploymentBenefitPlansLiabilitiesCurrent
52000 USD
CY2017 us-gaap Proceeds From Repurchase Of Equity
ProceedsFromRepurchaseOfEquity
3000000 USD
CY2017Q4 syn Exchange Percentage Of Unregistered Common Stock
ExchangePercentageOfUnregisteredCommonStock
0.5 pure
CY2017 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
0 pure
CY2016 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
0 pure
CY2015 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
0 pure
CY2016 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1
P7Y
CY2017Q4 us-gaap Equity Method Investment Ownership Percentage
EquityMethodInvestmentOwnershipPercentage
0.885 pure
CY2017Q4 us-gaap Minority Interest Ownership Percentage By Parent
MinorityInterestOwnershipPercentageByParent
0.115 pure
CY2015Q4 syn Warrant Liabilities
WarrantLiabilities
10566000 USD
CY2016 syn Issuance Of Warrants
IssuanceOfWarrants
15667000 USD
CY2015Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber
7908899 shares
CY2016 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod
50000000 shares
CY2017 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod
0 shares
CY2016 syn Share Based Compensation Arrangement By Share Based Payment Award Other Than Options Exercises In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOtherThanOptionsExercisesInPeriod
0 shares
CY2017 syn Share Based Compensation Arrangement By Share Based Payment Award Other Than Options Exercises In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOtherThanOptionsExercisesInPeriod
0 shares
CY2016 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeited In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod
567257 shares
CY2017 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeited In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod
25311834 shares
CY2016Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber
57341642 shares
CY2017Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber
32029809 shares
CY2016Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
1.60
CY2017Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
1.50
CY2017 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeitures Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue
1.72
CY2016 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeitures Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue
2.35
CY2017 syn Share Based Compensation Arrangement By Share Based Payment Award Other Than Options Exercises In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOtherThanOptionsExercisesInPeriodWeightedAverageGrantDateFairValue
0
CY2016 syn Share Based Compensation Arrangement By Share Based Payment Award Other Than Options Exercises In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOtherThanOptionsExercisesInPeriodWeightedAverageGrantDateFairValue
0
CY2016 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
1.58
CY2017 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
0
CY2015Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
1.79
CY2017Q4 us-gaap Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Stock Options
EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions
2900000 USD
CY2017 us-gaap Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
166000 USD
CY2016 us-gaap Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
814000 USD
CY2015 us-gaap Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
41000 USD
CY2017Q4 us-gaap Dividends Payable Current
DividendsPayableCurrent
73000 USD
CY2016Q4 us-gaap Proceeds From Issuance Or Sale Of Equity
ProceedsFromIssuanceOrSaleOfEquity
23300000 USD
CY2015Q4 us-gaap Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
15003000 USD
CY2016Q4 us-gaap Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
300000 USD
CY2017 us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
0.21 pure
CY2017 syn Options To Be Received Common Stock Shares
OptionsToBeReceivedCommonStockShares
2000000 shares
CY2016 us-gaap Payments To Acquire In Process Research And Development
PaymentsToAcquireInProcessResearchAndDevelopment
643000 USD
CY2015 us-gaap Payments To Acquire In Process Research And Development
PaymentsToAcquireInProcessResearchAndDevelopment
424000 USD
CY2017 us-gaap Line Of Credit Facility Periodic Payment Interest
LineOfCreditFacilityPeriodicPaymentInterest
381150 USD
CY2012Q1 us-gaap Officers Compensation
OfficersCompensation
348000 USD
CY2014Q2 us-gaap Officers Compensation
OfficersCompensation
385000 USD
CY2015 us-gaap Officers Compensation
OfficersCompensation
385000 USD
CY2016Q4 syn Operating Annual Lease Payments
OperatingAnnualLeasePayments
285843 USD
CY2017 us-gaap Lease And Rental Expense
LeaseAndRentalExpense
199000 USD
CY2016 us-gaap Lease And Rental Expense
LeaseAndRentalExpense
145000 USD
CY2015 us-gaap Lease And Rental Expense
LeaseAndRentalExpense
108000 USD
CY2017Q4 us-gaap Payments For Fees
PaymentsForFees
5500000 USD
CY2016 us-gaap Proceeds From Repurchase Of Equity
ProceedsFromRepurchaseOfEquity
3000000 USD
CY2017Q4 us-gaap Share Price
SharePrice
0.51
CY2016Q4 us-gaap Share Price
SharePrice
0.76
CY2016Q4 us-gaap Share Price
SharePrice
1.75
CY2017 us-gaap Fair Value Assumptions Expected Dividend Rate
FairValueAssumptionsExpectedDividendRate
0 pure
CY2016 us-gaap Fair Value Assumptions Expected Dividend Rate
FairValueAssumptionsExpectedDividendRate
0 pure
CY2016Q4 us-gaap Fair Value Assumptions Expected Dividend Rate
FairValueAssumptionsExpectedDividendRate
0 pure
CY2017 us-gaap Fair Value Assumptions Expected Volatility Rate
FairValueAssumptionsExpectedVolatilityRate
0.8 pure
CY2016 us-gaap Fair Value Assumptions Expected Volatility Rate
FairValueAssumptionsExpectedVolatilityRate
0.95 pure
CY2016Q4 us-gaap Fair Value Assumptions Expected Volatility Rate
FairValueAssumptionsExpectedVolatilityRate
0.95 pure
CY2017 us-gaap Fair Value Assumptions Risk Free Interest Rate
FairValueAssumptionsRiskFreeInterestRate
0.0186 pure
CY2016 us-gaap Fair Value Assumptions Risk Free Interest Rate
FairValueAssumptionsRiskFreeInterestRate
0.0141 pure
CY2016Q4 us-gaap Fair Value Assumptions Risk Free Interest Rate
FairValueAssumptionsRiskFreeInterestRate
0.0139 pure
CY2017 us-gaap Fair Value Assumptions Expected Term
FairValueAssumptionsExpectedTerm
P1Y9M14D
CY2016 us-gaap Fair Value Assumptions Expected Term
FairValueAssumptionsExpectedTerm
P2Y9M14D
CY2016Q4 us-gaap Fair Value Assumptions Expected Term
FairValueAssumptionsExpectedTerm
P5Y
CY2017Q4 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
0.35 pure

Files In Submission

Name View Source Status
0001144204-18-010286-index-headers.html Edgar Link pending
0001144204-18-010286-index.html Edgar Link pending
0001144204-18-010286.txt Edgar Link pending
0001144204-18-010286-xbrl.zip Edgar Link pending
FilingSummary.xml Edgar Link unprocessable
Financial_Report.xlsx Edgar Link pending
R1.htm Edgar Link pending
R10.htm Edgar Link pending
R11.htm Edgar Link pending
R12.htm Edgar Link pending
R13.htm Edgar Link pending
R14.htm Edgar Link pending
R15.htm Edgar Link pending
R16.htm Edgar Link pending
R17.htm Edgar Link pending
R18.htm Edgar Link pending
R19.htm Edgar Link pending
R2.htm Edgar Link pending
R20.htm Edgar Link pending
R21.htm Edgar Link pending
R22.htm Edgar Link pending
R23.htm Edgar Link pending
R24.htm Edgar Link pending
R25.htm Edgar Link pending
R26.htm Edgar Link pending
R27.htm Edgar Link pending
R28.htm Edgar Link pending
R29.htm Edgar Link pending
R3.htm Edgar Link pending
R30.htm Edgar Link pending
R31.htm Edgar Link pending
R32.htm Edgar Link pending
R33.htm Edgar Link pending
R34.htm Edgar Link pending
R35.htm Edgar Link pending
R36.htm Edgar Link pending
R37.htm Edgar Link pending
R38.htm Edgar Link pending
R39.htm Edgar Link pending
R4.htm Edgar Link pending
R40.htm Edgar Link pending
R41.htm Edgar Link pending
R42.htm Edgar Link pending
R43.htm Edgar Link pending
R44.htm Edgar Link pending
R45.htm Edgar Link pending
R46.htm Edgar Link pending
R47.htm Edgar Link pending
R48.htm Edgar Link pending
R5.htm Edgar Link pending
R6.htm Edgar Link pending
R7.htm Edgar Link pending
R8.htm Edgar Link pending
R9.htm Edgar Link pending
report.css Edgar Link pending
Show.js Edgar Link pending
syn-20171231.xml Edgar Link completed
syn-20171231.xsd Edgar Link pending
syn-20171231_cal.xml Edgar Link unprocessable
syn-20171231_def.xml Edgar Link unprocessable
syn-20171231_lab.xml Edgar Link unprocessable
syn-20171231_pre.xml Edgar Link unprocessable
tv485536_10k.htm Edgar Link pending
tv485536_ex10-53.htm Edgar Link pending
tv485536_ex10-54.htm Edgar Link pending
tv485536_ex21.htm Edgar Link pending
tv485536_ex23-1.htm Edgar Link pending
tv485536_ex31-1.htm Edgar Link pending
tv485536_ex32-1.htm Edgar Link pending
tv485536_img1.jpg Edgar Link pending
tv485536_img2.jpg Edgar Link pending
tv485536_img3.jpg Edgar Link pending