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2021 Q4 Form 10-K Financial Statement
#000141057822000405 Filed on March 16, 2022
Income Statement
Concept | 2021 Q4 | 2021 | 2020 Q4 |
---|---|---|---|
Revenue | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Cost Of Revenue | |||
YoY Change | |||
Gross Profit | |||
YoY Change | |||
Gross Profit Margin | |||
Selling, General & Admin | $2.486M | $6.474M | $1.153M |
YoY Change | 115.61% | 28.73% | -10.13% |
% of Gross Profit | |||
Research & Development | $2.779M | $7.800M | $980.0K |
YoY Change | 183.57% | 52.02% | -49.14% |
% of Gross Profit | |||
Depreciation & Amortization | $13.00K | $87.00K | $32.00K |
YoY Change | -59.38% | -56.72% | -44.83% |
% of Gross Profit | |||
Operating Expenses | $5.265M | $14.27M | $2.132M |
YoY Change | 146.95% | 40.49% | -33.58% |
Operating Profit | -$14.27M | ||
YoY Change | 40.49% | ||
Interest Expense | $2.000K | $6.000K | $0.00 |
YoY Change | -86.36% | -100.0% | |
% of Operating Profit | |||
Other Income/Expense, Net | $6.000K | ||
YoY Change | -86.36% | ||
Pretax Income | -$5.263M | -$14.27M | -$2.132M |
YoY Change | 146.86% | 41.04% | -32.19% |
Income Tax | $0.00 | ||
% Of Pretax Income | |||
Net Earnings | -$5.263M | -$14.27M | -$2.109M |
YoY Change | 149.55% | 42.06% | -32.83% |
Net Earnings / Revenue | |||
Basic Earnings Per Share | -$0.19 | ||
Diluted Earnings Per Share | -$398.2K | -$0.19 | -$99.77K |
COMMON SHARES | |||
Basic Shares Outstanding | 132.0M | 121.9M | |
Diluted Shares Outstanding | 121.9M |
Balance Sheet
Concept | 2021 Q4 | 2021 | 2020 Q4 |
---|---|---|---|
SHORT-TERM ASSETS | |||
Cash & Short-Term Investments | $67.33M | $67.33M | $6.227M |
YoY Change | 981.18% | 981.18% | -58.61% |
Cash & Equivalents | $67.33M | $67.33M | $6.227M |
Short-Term Investments | |||
Other Short-Term Assets | $1.533M | $1.533M | $1.238M |
YoY Change | 23.83% | 23.83% | -10.16% |
Inventory | |||
Prepaid Expenses | |||
Receivables | |||
Other Receivables | $0.00 | $469.0K | |
Total Short-Term Assets | $68.86M | $68.86M | $7.934M |
YoY Change | 767.89% | 767.89% | -51.7% |
LONG-TERM ASSETS | |||
Property, Plant & Equipment | $101.0K | $1.484M | $174.0K |
YoY Change | -41.95% | 227.59% | -77.86% |
Goodwill | $0.00 | ||
YoY Change | |||
Intangibles | |||
YoY Change | |||
Long-Term Investments | |||
YoY Change | |||
Other Assets | $23.00K | $23.00K | $23.00K |
YoY Change | 0.0% | 0.0% | 0.0% |
Total Long-Term Assets | $1.507M | $1.507M | $476.0K |
YoY Change | 216.6% | 216.6% | -41.16% |
TOTAL ASSETS | |||
Total Short-Term Assets | $68.86M | $68.86M | $7.934M |
Total Long-Term Assets | $1.507M | $1.507M | $476.0K |
Total Assets | $70.37M | $70.37M | $8.410M |
YoY Change | 736.68% | 736.68% | -51.2% |
SHORT-TERM LIABILITIES | |||
YoY Change | |||
Accounts Payable | $524.0K | $524.0K | $886.0K |
YoY Change | -40.86% | -40.86% | -61.73% |
Accrued Expenses | $1.928M | $3.030M | $925.0K |
YoY Change | 108.43% | 45.67% | -68.75% |
Deferred Revenue | |||
YoY Change | |||
Short-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Long-Term Debt Due | |||
YoY Change | |||
Total Short-Term Liabilities | $3.554M | $3.554M | $2.966M |
YoY Change | 19.82% | 19.82% | -43.77% |
LONG-TERM LIABILITIES | |||
Long-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Other Long-Term Liabilities | $1.403M | $1.403M | $186.0K |
YoY Change | 654.3% | 654.3% | -60.68% |
Total Long-Term Liabilities | $1.403M | $1.403M | $186.0K |
YoY Change | 654.3% | 654.3% | -60.68% |
TOTAL LIABILITIES | |||
Total Short-Term Liabilities | $3.554M | $3.554M | $2.966M |
Total Long-Term Liabilities | $1.403M | $1.403M | $186.0K |
Total Liabilities | $4.957M | $4.957M | $3.152M |
YoY Change | 57.27% | 1207.92% | 9.83% |
SHAREHOLDERS EQUITY | |||
Retained Earnings | -$271.3M | -$248.1M | |
YoY Change | 9.35% | ||
Common Stock | $336.7M | $240.9M | |
YoY Change | 39.79% | ||
Preferred Stock | |||
YoY Change | |||
Treasury Stock (at cost) | |||
YoY Change | |||
Treasury Stock Shares | |||
Shareholders Equity | $65.41M | $65.41M | -$4.767M |
YoY Change | |||
Total Liabilities & Shareholders Equity | $70.37M | $70.37M | $8.410M |
YoY Change | 736.68% | 736.68% | -51.2% |
Cashflow Statement
Concept | 2021 Q4 | 2021 | 2020 Q4 |
---|---|---|---|
OPERATING ACTIVITIES | |||
Net Income | -$5.263M | -$14.27M | -$2.109M |
YoY Change | 149.55% | 42.06% | -32.83% |
Depreciation, Depletion And Amortization | $13.00K | $87.00K | $32.00K |
YoY Change | -59.38% | -56.72% | -44.83% |
Cash From Operating Activities | -$4.810M | -$12.89M | -$3.132M |
YoY Change | 53.58% | 5.93% | -13.12% |
INVESTING ACTIVITIES | |||
Capital Expenditures | $0.00 | $14.00K | -$5.000K |
YoY Change | -100.0% | 55.56% | |
Acquisitions | |||
YoY Change | |||
Other Investing Activities | |||
YoY Change | |||
Cash From Investing Activities | $0.00 | -$14.00K | -$5.000K |
YoY Change | -100.0% | 55.56% | |
FINANCING ACTIVITIES | |||
Cash Dividend Paid | |||
YoY Change | |||
Common Stock Issuance & Retirement, Net | $65.96M | ||
YoY Change | 1863.68% | ||
Debt Paid & Issued, Net | $0.00 | ||
YoY Change | |||
Cash From Financing Activities | 0.000 | 74.00M | 3.359M |
YoY Change | -100.0% | 2103.1% | |
NET CHANGE | |||
Cash From Operating Activities | -4.810M | -12.89M | -3.132M |
Cash From Investing Activities | 0.000 | -14.00K | -5.000K |
Cash From Financing Activities | 0.000 | 74.00M | 3.359M |
Net Change In Cash | -4.810M | 61.10M | 222.0K |
YoY Change | -2266.67% | -792.88% | -106.16% |
FREE CASH FLOW | |||
Cash From Operating Activities | -$4.810M | -$12.89M | -$3.132M |
Capital Expenditures | $0.00 | $14.00K | -$5.000K |
Free Cash Flow | -$4.810M | -$12.90M | -$3.127M |
YoY Change | 53.82% | 5.97% | -13.26% |
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0 | |
CY2020 | syn |
Conversion Of Series B Preferred Stock To Common Stock
ConversionOfSeriesBPreferredStockToCommonStock
|
0 | |
CY2020 | us-gaap |
Profit Loss
ProfitLoss
|
-10116000 | |
CY2020Q4 | us-gaap |
Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
|
-7540000 | |
CY2021 | us-gaap |
Adjustments To Additional Paid In Capital Share Based Compensation Stock Options Requisite Service Period Recognition
AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationStockOptionsRequisiteServicePeriodRecognition
|
416000 | |
CY2021 | syn |
Stock Issued During Period At Market Offering Value
StockIssuedDuringPeriodAtMarketOfferingValue
|
65960000 | |
CY2021 | us-gaap |
Dividends Preferred Stock
DividendsPreferredStock
|
24000 | |
CY2021 | syn |
Stock Issued During Period Value Warrants Exercised
StockIssuedDuringPeriodValueWarrantsExercised
|
8042000 | |
CY2021 | syn |
Adjustments To Effect Of Preferred Stock Price
AdjustmentsToEffectOfPreferredStockPrice
|
0 | |
CY2021 | us-gaap |
Profit Loss
ProfitLoss
|
-14268000 | |
CY2021 | us-gaap |
Minority Interest Decrease From Distributions To Noncontrolling Interest Holders
MinorityInterestDecreaseFromDistributionsToNoncontrollingInterestHolders
|
0 | |
CY2021Q4 | us-gaap |
Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
|
65408000 | |
CY2021 | us-gaap |
Profit Loss
ProfitLoss
|
-14268000 | |
CY2020 | us-gaap |
Profit Loss
ProfitLoss
|
-10116000 | |
CY2021 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
416000 | |
CY2020 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
350000 | |
CY2021 | syn |
Subsidiary Stock Issues To Vendor
SubsidiaryStockIssuesToVendor
|
0 | |
CY2020 | syn |
Subsidiary Stock Issues To Vendor
SubsidiaryStockIssuesToVendor
|
178000 | |
CY2021 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
87000 | |
CY2020 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
201000 | |
CY2021 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
-174000 | |
CY2020 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
326000 | |
CY2021 | syn |
Increase Decrease Right Of Use Assets
IncreaseDecreaseRightOfUseAssets
|
166000 | |
CY2020 | syn |
Increase Decrease Right Of Use Assets
IncreaseDecreaseRightOfUseAssets
|
141000 | |
CY2021 | us-gaap |
Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
|
-363000 | |
CY2020 | us-gaap |
Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
|
-1429000 | |
CY2021 | us-gaap |
Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
|
1004000 | |
CY2020 | us-gaap |
Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
|
-851000 | |
CY2021 | us-gaap |
Increase Decrease In Employee Related Liabilities
IncreaseDecreaseInEmployeeRelatedLiabilities
|
110000 | |
CY2020 | us-gaap |
Increase Decrease In Employee Related Liabilities
IncreaseDecreaseInEmployeeRelatedLiabilities
|
-67000 | |
CY2021 | syn |
Increase Decrease Lease Liability
IncreaseDecreaseLeaseLiability
|
-216000 | |
CY2020 | syn |
Increase Decrease Lease Liability
IncreaseDecreaseLeaseLiability
|
-249000 | |
CY2021 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-12890000 | |
CY2020 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-12168000 | |
CY2021 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
14000 | |
CY2020 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
9000 | |
CY2021 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
-14000 | |
CY2020 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
-9000 | |
CY2021 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
65960000 | |
CY2020 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
3359000 | |
CY2021 | us-gaap |
Proceeds From Warrant Exercises
ProceedsFromWarrantExercises
|
8042000 | |
CY2020 | us-gaap |
Proceeds From Warrant Exercises
ProceedsFromWarrantExercises
|
0 | |
CY2021 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
74002000 | |
CY2020 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
3359000 | |
CY2021 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Excluding Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect
|
61098000 | |
CY2020 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Excluding Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect
|
-8818000 | |
CY2020Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
6227000 | |
CY2019Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
15045000 | |
CY2021Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
67325000 | |
CY2020Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
6227000 | |
CY2021 | syn |
Preferred Stock Price Adjustment
PreferredStockPriceAdjustment
|
7402000 | |
CY2020 | syn |
Preferred Stock Price Adjustment
PreferredStockPriceAdjustment
|
0 | |
CY2021 | syn |
Return Of Syn Biomics Stock
ReturnOfSynBiomicsStock
|
2774000 | |
CY2020 | syn |
Return Of Syn Biomics Stock
ReturnOfSynBiomicsStock
|
0 | |
CY2021 | syn |
Deemed Dividends With Beneficial Conversion Feature
DeemedDividendsWithBeneficialConversionFeature
|
1496000 | |
CY2020 | syn |
Deemed Dividends With Beneficial Conversion Feature
DeemedDividendsWithBeneficialConversionFeature
|
1380000 | |
CY2021 | us-gaap |
Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
|
1270000 | |
CY2020 | us-gaap |
Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
|
0 | |
CY2021 | us-gaap |
Dividends Preferred Stock Paidinkind
DividendsPreferredStockPaidinkind
|
24000 | |
CY2020 | us-gaap |
Dividends Preferred Stock Paidinkind
DividendsPreferredStockPaidinkind
|
254000 | |
CY2021 | syn |
Warrant Exercise Price Adjustment
WarrantExercisePriceAdjustment
|
0 | |
CY2020 | syn |
Warrant Exercise Price Adjustment
WarrantExercisePriceAdjustment
|
880000 | |
CY2021 | us-gaap |
Number Of Operating Segments
NumberOfOperatingSegments
|
1 | |
CY2021Q4 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
67300000 | |
CY2021 | syn |
Proceeds From Issuance Atm Offering Net Of Issuance Costs
ProceedsFromIssuanceAtmOfferingNetOfIssuanceCosts
|
66000000 | |
CY2021 | us-gaap |
Proceeds From Warrant Exercises
ProceedsFromWarrantExercises
|
8000000.0 | |
CY2021 | us-gaap |
Use Of Estimates
UseOfEstimates
|
<p style="font-family:'Times New Roman','Times','serif';font-size:10pt;font-style:italic;font-weight:bold;margin:0pt 0pt 12pt 0pt;">Use of Estimates</p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;margin:0pt 0pt 12pt 0pt;">The preparation of consolidated financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect the amounts reported in the consolidated financial statements and accompanying notes. Such estimates and assumptions impact, among others, the following: the estimated useful lives for property and equipment, fair value of warrants, preferred stock and stock options granted for services or compensation, respectively, and the valuation allowance for deferred tax assets due to continuing and expected future operating losses.</p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;margin:0pt 0pt 12pt 0pt;">Making estimates requires management to exercise significant judgment. It is at least reasonably possible that the estimate of the effect of a condition, situation or set of consolidated financial statements, which management considered in formulating its estimate could change in the near term due to one or more future confirming events. Accordingly, actual results could differ from those estimates.</p> | |
CY2020Q4 | us-gaap |
Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
|
1707000 | |
CY2020 | syn |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumption Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionExercisePrice
|
0.42 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
|
0 | |
CY2020 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
|
0 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
|
0.92 | |
CY2021 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1
|
P4Y3M18D | |
CY2020 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1
|
P4Y3M18D | |
CY2021Q4 | us-gaap |
Equity Method Investment Ownership Percentage
EquityMethodInvestmentOwnershipPercentage
|
0.830 | |
CY2021 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
87000 | |
CY2020 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
201000 | |
CY2021Q4 | us-gaap |
Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
|
978000 | |
CY2020Q4 | us-gaap |
Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
|
868000 | |
CY2020 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
|
0.88 | |
CY2021Q4 | us-gaap |
Accrued Liabilities Current And Noncurrent
AccruedLiabilitiesCurrentAndNoncurrent
|
700000 | |
CY2020Q4 | us-gaap |
Prepaid Expense Current And Noncurrent
PrepaidExpenseCurrentAndNoncurrent
|
500000 | |
CY2021Q4 | us-gaap |
Prepaid Expense Current And Noncurrent
PrepaidExpenseCurrentAndNoncurrent
|
500000 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
|
0.0112 | |
CY2020 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
|
0.0031 | |
CY2021Q4 | us-gaap |
Prepaid Insurance
PrepaidInsurance
|
803000 | |
CY2020Q4 | us-gaap |
Prepaid Insurance
PrepaidInsurance
|
639000 | |
CY2021Q4 | syn |
Prepaid Clinical Research Organizations Expense Current
PrepaidClinicalResearchOrganizationsExpenseCurrent
|
458000 | |
CY2020Q4 | syn |
Prepaid Clinical Research Organizations Expense Current
PrepaidClinicalResearchOrganizationsExpenseCurrent
|
470000 | |
CY2021Q4 | syn |
Prepaid Consulting Subscriptions And Other Expenses
PrepaidConsultingSubscriptionsAndOtherExpenses
|
272000 | |
CY2020Q4 | syn |
Prepaid Consulting Subscriptions And Other Expenses
PrepaidConsultingSubscriptionsAndOtherExpenses
|
90000 | |
CY2021Q4 | us-gaap |
Other Receivables Net Current
OtherReceivablesNetCurrent
|
0 | |
CY2020Q4 | us-gaap |
Other Receivables Net Current
OtherReceivablesNetCurrent
|
469000 | |
CY2021Q4 | syn |
Prepaid Manufacturing Expense
PrepaidManufacturingExpense
|
0 | |
CY2020Q4 | syn |
Prepaid Manufacturing Expense
PrepaidManufacturingExpense
|
39000 | |
CY2021Q4 | us-gaap |
Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
|
1533000 | |
CY2021Q4 | us-gaap |
Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
|
932000 | |
CY2020Q4 | us-gaap |
Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
|
1263000 | |
CY2021Q4 | us-gaap |
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
|
831000 | |
CY2020Q4 | us-gaap |
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
|
1089000 | |
CY2021Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
101000 | |
CY2020Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
174000 | |
CY2021Q4 | syn |
Accrued Vendor Payments
AccruedVendorPayments
|
1028000 | |
CY2020Q4 | syn |
Accrued Vendor Payments
AccruedVendorPayments
|
225000 | |
CY2021Q4 | syn |
Accrued Clinical Consulting Services
AccruedClinicalConsultingServices
|
696000 | |
CY2020Q4 | syn |
Accrued Clinical Consulting Services
AccruedClinicalConsultingServices
|
700000 | |
CY2021Q4 | syn |
Accrued Manufacturing Costs
AccruedManufacturingCosts
|
204000 | |
CY2021Q4 | us-gaap |
Accrued Liabilities Current
AccruedLiabilitiesCurrent
|
1928000 | |
CY2021 | syn |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumption Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionExercisePrice
|
0.33 | |
CY2018Q4 | us-gaap |
Proceeds From Issuance Or Sale Of Equity
ProceedsFromIssuanceOrSaleOfEquity
|
18600000 | |
CY2018Q4 | us-gaap |
Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1
ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
|
1.38 | |
CY2020Q4 | us-gaap |
Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1
ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
|
1.38 | |
CY2020Q4 | us-gaap |
Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
|
0.001 | |
CY2020Q4 | syn |
Warrant Exercise Price Adjustment
WarrantExercisePriceAdjustment
|
900000 | |
CY2020Q4 | us-gaap |
Accrued Liabilities Current
AccruedLiabilitiesCurrent
|
925000 | |
CY2021Q4 | us-gaap |
Accrued Bonuses Current
AccruedBonusesCurrent
|
886000 | |
CY2020Q4 | us-gaap |
Accrued Bonuses Current
AccruedBonusesCurrent
|
724000 | |
CY2021Q4 | us-gaap |
Accrued Vacation Current
AccruedVacationCurrent
|
92000 | |
CY2020Q4 | us-gaap |
Accrued Vacation Current
AccruedVacationCurrent
|
144000 | |
CY2021Q4 | us-gaap |
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Stock Options
EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions
|
771000 | |
CY2020 | us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
0 | |
CY2021 | us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
0 | |
CY2021Q4 | syn |
Deferred Tax Assets Stock Issued For Milestone Payment
DeferredTaxAssetsStockIssuedForMilestonePayment
|
236000 | |
CY2020Q4 | syn |
Deferred Tax Assets Stock Issued For Milestone Payment
DeferredTaxAssetsStockIssuedForMilestonePayment
|
262000 | |
CY2021 | us-gaap |
Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
|
0 | |
CY2021 | us-gaap |
Proceeds From Issuance Of Warrants
ProceedsFromIssuanceOfWarrants
|
8000000.0 | |
CY2020Q4 | syn |
Stock Issued During Period Shares Warrants Exercised
StockIssuedDuringPeriodSharesWarrantsExercised
|
0 | |
CY2019Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber
|
18714999 | |
CY2019Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
|
3.24 | |
CY2020 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeited In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod
|
714286 | |
CY2020 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeitures Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue
|
50.05 | |
CY2020Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber
|
18000713 | |
CY2020Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
|
0.69 | |
CY2021 | syn |
Share Based Compensation Arrangement By Share Based Payment Award Other Than Options Exercises In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOtherThanOptionsExercisesInPeriod
|
11655747 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeitures Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue
|
0.69 | |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber
|
6344966 | |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
|
0.69 | |
CY2017Q4 | us-gaap |
Warrants Not Settleable In Cash Fair Value Disclosure
WarrantsNotSettleableInCashFairValueDisclosure
|
9000 | |
CY2018Q4 | us-gaap |
Proceeds From Issuance Or Sale Of Equity
ProceedsFromIssuanceOrSaleOfEquity
|
18600000 | |
CY2020Q4 | syn |
Preferred Stock Shares Converted
PreferredStockSharesConverted
|
1.38 | |
CY2020Q4 | us-gaap |
Preferred Stock Convertible Conversion Price Decrease
PreferredStockConvertibleConversionPriceDecrease
|
0.69 | |
CY2021 | syn |
Preferred Stock Shares Converted
PreferredStockSharesConverted
|
3973 | |
CY2020 | syn |
Preferred Stock Shares Converted
PreferredStockSharesConverted
|
3665 | |
CY2021Q1 | us-gaap |
Preferred Stock Convertible Conversion Price Decrease
PreferredStockConvertibleConversionPriceDecrease
|
1.50 | |
CY2021Q1 | us-gaap |
Convertible Preferred Stock Shares Issued Upon Conversion
ConvertiblePreferredStockSharesIssuedUponConversion
|
8996768 | |
CY2021 | syn |
Estimated Fair Value Of Inducement Consideration
EstimatedFairValueOfInducementConsideration
|
7400000 | |
CY2021 | syn |
Estimated Fair Value Of Inducement Consideration
EstimatedFairValueOfInducementConsideration
|
7400000 | |
CY2018Q3 | us-gaap |
Related Party Transaction Expenses From Transactions With Related Party
RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty
|
328000 | |
CY2018Q3 | syn |
Fair Value Of Shares Issued
FairValueOfSharesIssued
|
285000 | |
CY2020Q4 | syn |
Cost Of Living Adjustments Percentage
CostOfLivingAdjustmentsPercentage
|
0.625 | |
CY2021Q4 | us-gaap |
Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
|
0.085 | |
CY2021 | us-gaap |
Operating Lease Cost
OperatingLeaseCost
|
280000 | |
CY2020 | us-gaap |
Operating Lease Cost
OperatingLeaseCost
|
209000 | |
CY2021Q4 | syn |
Deferred Tax Assets Stock Issued For Acquisition Of Program
DeferredTaxAssetsStockIssuedForAcquisitionOfProgram
|
1462000 | |
CY2020Q4 | syn |
Deferred Tax Assets Stock Issued For Acquisition Of Program
DeferredTaxAssetsStockIssuedForAcquisitionOfProgram
|
1436000 | |
CY2021Q4 | syn |
Deferred Tax Assets Stock Issued Forlicense Agreement
DeferredTaxAssetsStockIssuedForlicenseAgreement
|
1363000 | |
CY2020Q4 | syn |
Deferred Tax Assets Stock Issued Forlicense Agreement
DeferredTaxAssetsStockIssuedForlicenseAgreement
|
1574000 | |
CY2021 | us-gaap |
Operating Lease Payments
OperatingLeasePayments
|
321000 | |
CY2020 | us-gaap |
Operating Lease Payments
OperatingLeasePayments
|
309000 | |
CY2021 | syn |
Non Cash Addition Of Right Of Use Assets
NonCashAdditionOfRightOfUseAssets
|
538000 | |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Next Twelve Months
LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
|
247000 | |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Two
LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
|
327000 | |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Three
LesseeOperatingLeaseLiabilityPaymentsDueYearThree
|
337000 | |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Four
LesseeOperatingLeaseLiabilityPaymentsDueYearFour
|
347000 | |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Five
LesseeOperatingLeaseLiabilityPaymentsDueYearFive
|
357000 | |
CY2021Q4 | syn |
Lessee Operating Lease Liability Payments Due Year Six
LesseeOperatingLeaseLiabilityPaymentsDueYearSix
|
368000 | |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
|
1983000 | |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Undiscounted Excess Amount
LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
|
456000 | |
CY2021Q4 | us-gaap |
Operating Lease Liability
OperatingLeaseLiability
|
1527000 | |
CY2021Q4 | us-gaap |
Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
|
124000 | |
CY2021Q4 | us-gaap |
Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
|
1403000 | |
CY2017Q4 | us-gaap |
Payments For Fees
PaymentsForFees
|
4500000 | |
CY2020 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
0 | |
CY2021 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
0 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.0646 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Enacted Tax Rate
EffectiveIncomeTaxRateReconciliationChangeInEnactedTaxRate
|
0.0818 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.0645 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Enacted Tax Rate
EffectiveIncomeTaxRateReconciliationChangeInEnactedTaxRate
|
0.0817 | |
CY2021 | us-gaap |
Current Federal Tax Expense Benefit
CurrentFederalTaxExpenseBenefit
|
-3045000 | |
CY2020 | us-gaap |
Current Federal Tax Expense Benefit
CurrentFederalTaxExpenseBenefit
|
-2124000 | |
CY2021 | us-gaap |
Current State And Local Tax Expense Benefit
CurrentStateAndLocalTaxExpenseBenefit
|
-931000 | |
CY2020 | us-gaap |
Current State And Local Tax Expense Benefit
CurrentStateAndLocalTaxExpenseBenefit
|
-616000 | |
CY2021 | us-gaap |
Tax Adjustments Settlements And Unusual Provisions
TaxAdjustmentsSettlementsAndUnusualProvisions
|
0 | |
CY2020 | us-gaap |
Tax Adjustments Settlements And Unusual Provisions
TaxAdjustmentsSettlementsAndUnusualProvisions
|
0 | |
CY2021 | us-gaap |
Income Tax Reconciliation Nondeductible Expense Meals And Entertainment
IncomeTaxReconciliationNondeductibleExpenseMealsAndEntertainment
|
0 | |
CY2020 | us-gaap |
Income Tax Reconciliation Nondeductible Expense Meals And Entertainment
IncomeTaxReconciliationNondeductibleExpenseMealsAndEntertainment
|
0 | |
CY2021 | us-gaap |
Income Tax Reconciliation Nondeductible Expense Share Based Compensation Cost
IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost
|
32000 | |
CY2020 | us-gaap |
Income Tax Reconciliation Nondeductible Expense Share Based Compensation Cost
IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost
|
32000 | |
CY2021 | us-gaap |
Income Tax Reconciliation State And Local Income Taxes
IncomeTaxReconciliationStateAndLocalIncomeTaxes
|
932000 | |
CY2020 | us-gaap |
Income Tax Reconciliation State And Local Income Taxes
IncomeTaxReconciliationStateAndLocalIncomeTaxes
|
-1221000 | |
CY2021 | us-gaap |
Income Tax Reconciliation Income Tax Expense Benefit At Federal Statutory Income Tax Rate
IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate
|
0 | |
CY2020 | us-gaap |
Income Tax Reconciliation Income Tax Expense Benefit At Federal Statutory Income Tax Rate
IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate
|
0 | |
CY2021 | us-gaap |
Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
|
-3012000 | |
CY2020 | us-gaap |
Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
|
-3929000 | |
CY2021 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
0 | |
CY2020 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
0 | |
CY2021Q4 | syn |
Deferred Tax Assets Stocks Issued For Services
DeferredTaxAssetsStocksIssuedForServices
|
1504000 | |
CY2020Q4 | syn |
Deferred Tax Assets Stocks Issued For Services
DeferredTaxAssetsStocksIssuedForServices
|
1428000 | |
CY2021Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits
|
27000 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits
|
42000 | |
CY2021Q4 | syn |
Deferred Tax Assets Tax Deferred Expense Amortizable License Fee
DeferredTaxAssetsTaxDeferredExpenseAmortizableLicenseFee
|
4000 | |
CY2020Q4 | syn |
Deferred Tax Assets Tax Deferred Expense Amortizable License Fee
DeferredTaxAssetsTaxDeferredExpenseAmortizableLicenseFee
|
5000 | |
CY2021Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
16884000 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
12540000 | |
CY2021Q4 | us-gaap |
Deferred Tax Assets Gross
DeferredTaxAssetsGross
|
21480000 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Gross
DeferredTaxAssetsGross
|
17287000 | |
CY2021Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
21480000 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
17287000 | |
CY2021Q4 | us-gaap |
Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
|
0 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
|
0 | |
CY2021Q4 | us-gaap |
Operating Loss Carryforwards
OperatingLossCarryforwards
|
58300000 | |
CY2021 | syn |
Operating Loss Carryforwards Expire Date
OperatingLossCarryforwardsExpireDate
|
2037 | |
CY2021Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
21500000 | |
CY2021Q4 | us-gaap |
Deferred Tax Assets Net
DeferredTaxAssetsNet
|
4200000 |