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$TSHA
$4.25 +$0.24 (5.99%) Close

Ownership

13F as of Q2 2026 · 325.8M shares outstanding

Who owns TSHA?

By type of holder
Institutions 91.5% Insiders 6.8% Everyone else 1.7%
Concentration Top 10 holders own 59.5%
Paul B Manning 7.9% · Avoro Capital Advisors LLC 7.3%
Institutional ownership
91.5%
+10.0 pts vs last qtr
Institutional holders
206
+15 vs last qtr
Net shares bought
+32.4M
by institutions in Q2 2026
New / sold out
40 / 25
positions opened vs closed

How is ownership changing?

Institutions, last 8 quarters

Biggest buyers in Q2 2026
  • MPM Bioimpact LLC NEW +4.5M
  • Wellington Management Group LLP +3.3M

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Biggest sellers in Q2 2026
  • Deerfield Management Company, L.P. SOLD OUT −2.7M
  • SG Americas Securities, LLC −2.0M

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Who is planning to sell?

Notices of proposed sale, last 12 months
$7.83M
17 notices from 8 people
Shares covered
1.5M
0.47% of the company
Arranged in advance
41%
of the value is under a 10b5-1 plan
Under a 10b5-1 plan No plan
$0$1.9M$3.8MNov 2025: $1.8M without a planNovDecJan 2026: $996.0K under a 10b5-1 planJan 2026: $2.8M without a planJanFeb 2026: $34.9K without a planFebMarApr 2026: $926.0K under a 10b5-1 planAprMayJunJul 2026: $1.3M under a 10b5-1 planJulAugSepOct
Largest proposed sellers
  • Nagendran Sukumar Officer $5.02M
  • Sean P. Nolan Officer $856K

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Every notice on Red Flags →

A Form 144 is notice of a planned sale, not the sale itself. What insiders actually sold is on Insider Transactions.

Is your stake being diluted?

Diluted share count, FY2023–FY2025
+175.3%
+65.93% a year
Each share's claim on the business
−63.7%
shrank without buying or selling a share
Spent on buybacks vs paid in stock
— vs $34.3M
over 3 fiscal years
Diluted shares, split-adjusted
112.6M217.8M322.9M2023: 116.1M shares'232024: 250.1M shares'242025: 319.7M shares'25
Buybacks Stock-based comp
$0$6.6M$13.3M2023 buybacks: $02023 stock comp: $7.9M'232024 buybacks: $02024 stock comp: $13.1M'242025 buybacks: $02025 stock comp: $13.3M'25

How patient are the owners?

Institutional shares by how long they've been held
5+ years31% 3–5 years1% 1–3 years55% Under 1 year13%
Quarterly turnover
11.2%
of institutional shares changed hands
Top 10 managers, median time held
5 years

Super Investors

Investment managers reporting TSHA on Form 13F
AC
Avoro Capital Advisors LLC
Shares
23.9M
% of company
7.33%
Change vs last qtr
+2.2M (+10.1%)
Held since
2023
RC
Ra Capital Management, L.P.
Shares
23.6M
% of company
7.23%
Change vs last qtr
Unchanged
Held since
2023

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Institutional Funds

Mutual funds and ETFs reporting TSHA on Form N-PORT; together they hold 18.3% of the company
VT
Position value
$62.2M
% of company
2.80%
% of the fund
0.00%
As of
June 30, 2026
IR
iShares Trust
Position value
$42.5M
% of company
1.92%
% of the fund
0.05%
As of
June 30, 2026

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Insiders and 5%+ holders

From Forms 3/4/5 and Schedules 13D/G
PB
Paul B Manning
5%+ holder13D · 9.8%
Shares
25.6M
% of company
7.86%
Change vs last qtr
—
Held since
—
PB
The Paul B. Manning Revocable Trust dated May 10, 2000
5%+ holder13D · 5.6%
Shares
14.7M
% of company
4.52%
Change vs last qtr
—
Held since
—

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