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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation and amortization expense | |||||
| Noncash lease expense | |||||
| Stock-based compensation expense | |||||
| Non-cash interest expense on liability related to sales of future royalties and milestones, net of issuance costs accretion | |||||
| Impairment of long-lived assets | |||||
| Inventory write-down | |||||
| Change in fair value of Convertible Notes | |||||
| Non-cash lease expense | |||||
| Accretion of net discounts on short-term investments | |||||
| Realized gain on sale of property and equipment | |||||
| Interest accrued on Convertible Notes | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable, net - related party | |||||
| Inventory | |||||
| Income tax receivable | |||||
| Other receivables | |||||
| Prepaid expenses | |||||
| Prepaid expenses and other assets | |||||
| Accounts payable and accrued expenses | |||||
| Operating lease liabilities | |||||
| Reimbursement of lease incentive | |||||
| Other | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities: | |||||
| Proceeds from maturities of available-for-sale marketable securities | |||||
| Proceeds from redemptions of available-for-sale marketable securities, at par | |||||
| Proceeds from sale of available-for-sale marketable securities | |||||
| Purchases of available-for-sale marketable securities | |||||
| Purchases of property and equipment | |||||
| Purchases of short-term investments | |||||
| Maturities of short-term investments | |||||
| Net cash used in investing activities | |||||
| Cash flows from financing activities: | |||||
| Payments to royalty purchase and sale agreement | |||||
| Proceeds from royalty purchase and sale agreement, net of $1.0 million of issuance costs | |||||
| Net proceeds from sales of common stock under open market sales agreement | |||||
| Cash acquired in connection with the Merger | |||||
| Payments for Merger transaction costs | |||||
| Proceeds from Convertible Notes | |||||
| Proceeds from exercise of stock options | |||||
| Net cash provided by financing activities | |||||
| Net (decrease) increase in cash, cash equivalents and restricted cash | |||||
| Net (decrease) increase in cash and cash equivalents | |||||
| Cash and cash equivalents - beginning of year | |||||
| Cash and cash equivalents - end of year | |||||
| Non-cash investing and financing activities | |||||
| Receivable for additional HCR financing earned | |||||
| Incremental right-of-use asset in exchange for non-cash lease liability from modification of lease | |||||
| Transfer of property and equipment per lease assignment | |||||
| Initial direct costs included as right-of-use asset from modification of lease | |||||
| Accrual for leasehold improvements | |||||
| Merger transaction costs included in accounts payable and accrued expenses | |||||
| Conversion of redeemable convertible preferred stock to common stock | |||||
| Conversion of Convertible Notes to common stock | |||||
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