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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash Flows From Operating Activities: | |||||
| Net loss | |||||
| Net income (loss) from discontinued operations | |||||
| Net loss from continuing operations | |||||
| Adjustments to reconcile net loss to net cash provided by (used in) operating activities: | |||||
| Depreciation and amortization | |||||
| Share based compensation | |||||
| In-process research and development | |||||
| Loss on extinguishment of debt | |||||
| Loss on allowance for inventory | |||||
| Amortization of debt discount and issuance costs | |||||
| Impairment of intangible assets | |||||
| Amortization of discounts on investments | |||||
| Other | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Inventory | |||||
| Income taxes | |||||
| Prepaid expenses and other current and non-current assets | |||||
| Change in lease assets and liabilities, net | |||||
| Accounts payable | |||||
| Accrued expenses | |||||
| Deferred revenue, current and non-current | |||||
| Other current and non-current liabilities | |||||
| Net cash provided by (used in) operating activities - continuing operations | |||||
| Net cash (used in) provided by operating activities - discontinued operations | |||||
| Net cash provided by (used) in operating activities | |||||
| Cash Flows From Investing Activities: | |||||
| Proceeds from the sale and maturity of marketable debt securities | |||||
| Purchase of marketable debt securities | |||||
| Purchase of fixed assets | |||||
| Purchase of intangible assets | |||||
| Payment of milestone | |||||
| Other | |||||
| Net cash provided by (used in) investing activities - continuing operations | |||||
| Net cash provided by investing activities - discontinued operations | |||||
| Net cash provided by investing activities | |||||
| Cash Flows From Financing Activities: | |||||
| Payment of guaranteed minimum royalty | |||||
| Proceeds from issuance of 2029 convertible senior notes | |||||
| Payment of debt issuance costs | |||||
| Repayment of 2025 convertible senior notes | |||||
| Proceeds from the issuance of common stock, net of issuance costs | |||||
| Total proceeds from the issuance of common stock, net of issuance costs | |||||
| Proceeds from the issuance of pre-funded warrants, net of issuance costs | |||||
| Proceeds from exercise of stock options | |||||
| Proceeds from the issuances under the employee stock purchase plan | |||||
| Proceeds from issuance of common stock | |||||
| At-The-Market Offering | |||||
| Net cash (used in) provided by financing activities - continuing operations | |||||
| Net cash used in financing activities - discontinued operations | |||||
| Net cash (used in) provided by financing activities | |||||
| Effect of exchange rate changes on cash | |||||
| Net increase (decrease) in cash and cash equivalents | |||||
| Cash and cash equivalents, beginning of year | |||||
| Cash and cash equivalents, end of year | |||||
| Supplemental Disclosure of Cash Flow Information: | |||||
| Operating cash flows used for operating leases | |||||
| Cash paid for interest | |||||
| Cash paid for income taxes | |||||
| Non-cash investing and financing activities: | |||||
| Accrued royalty in excess of minimum payable to the sellers of Thiola | |||||
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