2016 Form 10-K Financial Statement

#000143853317000005 Filed on March 01, 2017

View on sec.gov

Income Statement

Concept 2016 2015 Q4 2015 Q3
Revenue $133.6M $30.45M $28.01M
YoY Change 33.74% 116.17% 235.47%
Cost Of Revenue $4.554M $760.0K $513.0K
YoY Change 108.42% 123.53% 159.09%
Gross Profit $129.0M $29.69M $27.49M
YoY Change 32.07% 115.93% 237.33%
Gross Profit Margin 96.59% 97.51% 98.17%
Selling, General & Admin $91.94M $18.95M $22.31M
YoY Change 15.59% 2.65% 28.41%
% of Gross Profit 71.25% 63.83% 81.14%
Research & Development $70.82M $15.37M $14.06M
YoY Change 40.45% 8.32% 11.21%
% of Gross Profit 54.89% 51.77% 51.16%
Depreciation & Amortization $16.14M $3.970M $3.880M
YoY Change 20.48% 113.44% 109.73%
% of Gross Profit 12.5% 13.37% 14.11%
Operating Expenses $191.8M $45.65M $48.50M
YoY Change 27.33% 39.26% 60.52%
Operating Profit -$58.21M -$15.20M -$20.50M
YoY Change 14.71% -18.68% -6.27%
Interest Expense $4.700M -$4.210M -$695.0K
YoY Change -38.96% -59.24% -73.56%
% of Operating Profit
Other Income/Expense, Net $632.0K $2.210M $164.8M
YoY Change -99.6% -121.39% 4140.67%
Pretax Income -$57.58M -$12.99M $144.3M
YoY Change -154.6% -55.23% -902.78%
Income Tax -$9.679M -$10.53M $38.76M
% Of Pretax Income 26.85%
Net Earnings -$47.90M -$2.469M $105.6M
YoY Change -140.86% -91.49% -687.2%
Net Earnings / Revenue -35.86% -8.11% 377.0%
Basic Earnings Per Share -$1.29 -$0.07 $2.95
Diluted Earnings Per Share -$1.29 -$0.14 $1.78
COMMON SHARES
Basic Shares Outstanding 37.00M shares 36.15M shares 35.74M shares
Diluted Shares Outstanding 38.29M shares 42.75M shares

Balance Sheet

Concept 2016 2015 Q4 2015 Q3
SHORT-TERM ASSETS
Cash & Short-Term Investments $255.9M $229.6M $235.3M
YoY Change 11.45% 727.1% 522.43%
Cash & Equivalents $41.00M $37.81M $140.6M
Short-Term Investments $214.9M $191.8M $94.68M
Other Short-Term Assets $8.300M $10.50M $2.000M
YoY Change -20.95% 1212.5% -13.04%
Inventory $2.800M $2.536M $2.650M
Prepaid Expenses
Receivables $18.50M $12.46M $13.50M
Other Receivables $46.90M $46.80M $46.50M
Total Short-Term Assets $332.4M $301.9M $300.0M
YoY Change 10.1% 708.73% 560.69%
LONG-TERM ASSETS
Property, Plant & Equipment $2.600M $428.0K $478.0K
YoY Change 550.0% -36.21% -20.33%
Goodwill $936.0K $936.0K
YoY Change 0.0%
Intangibles $161.5M
YoY Change
Long-Term Investments
YoY Change
Other Assets $7.400M $1.859M $2.006M
YoY Change 289.47% -17.92% -12.78%
Total Long-Term Assets $192.9M $210.3M $211.7M
YoY Change -8.32% 114.32% 110.62%
TOTAL ASSETS
Total Short-Term Assets $332.4M $301.9M $300.0M
Total Long-Term Assets $192.9M $210.3M $211.7M
Total Assets $525.3M $512.3M $511.6M
YoY Change 2.54% 278.14% 250.67%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable $7.500M $7.639M $4.893M
YoY Change -1.32% 7.23% -56.7%
Accrued Expenses $23.50M $23.82M $22.32M
YoY Change 26.34% -14.57% 90.75%
Deferred Revenue
YoY Change
Short-Term Debt $0.00 $0.00 $0.00
YoY Change -100.0%
Long-Term Debt Due $1.000M
YoY Change -33.33%
Total Short-Term Liabilities $83.30M $86.98M $101.9M
YoY Change -4.25% -19.12% 107.63%
LONG-TERM LIABILITIES
Long-Term Debt $44.40M $43.80M $43.70M
YoY Change 1.37% 1.15% 1.39%
Other Long-Term Liabilities $83.40M $3.066M $13.92M
YoY Change 45.8% 89.61% -78.16%
Total Long-Term Liabilities $127.8M $3.066M $13.92M
YoY Change 26.53% 89.61% -86.97%
TOTAL LIABILITIES
Total Short-Term Liabilities $83.30M $86.98M $101.9M
Total Long-Term Liabilities $127.8M $3.066M $13.92M
Total Liabilities $217.5M $212.3M $220.6M
YoY Change 2.45% 22.91% 41.33%
SHAREHOLDERS EQUITY
Retained Earnings -$65.15M -$62.68M
YoY Change -63.64%
Common Stock $365.8M $353.8M
YoY Change 159.71%
Preferred Stock
YoY Change
Treasury Stock (at cost) $0.00 $0.00
YoY Change -100.0%
Treasury Stock Shares 0.000 shares 0.000 shares
Shareholders Equity $307.8M $300.0M $291.0M
YoY Change
Total Liabilities & Shareholders Equity $525.3M $512.3M $511.6M
YoY Change 2.54% 278.14% 250.67%

Cashflow Statement

Concept 2016 2015 Q4 2015 Q3
OPERATING ACTIVITIES
Net Income -$47.90M -$2.469M $105.6M
YoY Change -140.86% -91.49% -687.2%
Depreciation, Depletion And Amortization $16.14M $3.970M $3.880M
YoY Change 20.48% 113.44% 109.73%
Cash From Operating Activities -$3.441M -$3.550M $1.590M
YoY Change 147.73% -60.95% -110.26%
INVESTING ACTIVITIES
Capital Expenditures $1.428M -$1.720M -$3.880M
YoY Change 6390.91% 2050.0% 2486.67%
Acquisitions $615.0K
YoY Change -98.16%
Other Investing Activities $22.29M -$98.74M $55.01M
YoY Change -130.3% -4916.59% -2995.26%
Cash From Investing Activities $10.37M -$100.5M $51.12M
YoY Change -112.87% -5199.49% -2581.55%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net $0.00
YoY Change -100.0%
Debt Paid & Issued, Net $0.00
YoY Change
Cash From Financing Activities -$3.849M 1.230M -39.87M
YoY Change -103.79% -332.08% -1226.27%
NET CHANGE
Cash From Operating Activities -$3.441M -3.550M 1.590M
Cash From Investing Activities $10.37M -100.5M 51.12M
Cash From Financing Activities -$3.849M 1.230M -39.87M
Net Change In Cash $3.080M -102.8M 12.84M
YoY Change -84.29% 1243.53% -191.58%
FREE CASH FLOW
Cash From Operating Activities -$3.441M -$3.550M $1.590M
Capital Expenditures $1.428M -$1.720M -$3.880M
Free Cash Flow -$4.869M -$1.830M $5.470M
YoY Change 245.07% -79.69% -135.64%

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CY2015 us-gaap Adjustments Noncash Items To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities
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CY2016 us-gaap Adjustments Noncash Items To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities
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359000 USD
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CY2015 us-gaap Allocated Share Based Compensation Expense
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CY2016 us-gaap Allocated Share Based Compensation Expense
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CY2016Q4 us-gaap Allowance For Doubtful Accounts Receivable
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300000 USD
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0 USD
CY2015 us-gaap Amortization Of Debt Discount Premium
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398000 USD
CY2016 us-gaap Amortization Of Debt Discount Premium
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1097000 USD
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4708000 USD
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0 USD
CY2016 us-gaap Amortization Of Financing Costs
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0 USD
CY2014 us-gaap Amortization Of Financing Costs And Discounts
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CY2015 us-gaap Amortization Of Financing Costs And Discounts
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1340000 USD
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656000 USD
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8000 USD
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651000 USD
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7000 USD
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550000 USD
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192442000 USD
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215414000 USD
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191799000 USD
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214871000 USD
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2300000 USD
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0 USD
CY2015 us-gaap Business Combination Contingent Consideration Arrangements Change In Amount Of Contingent Consideration Liability1
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18383000 USD
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12207000 USD
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3197000 USD
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0.0001
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0.0001
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100000000 shares
CY2016Q4 us-gaap Common Stock Shares Authorized
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571000 USD
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2185000 USD
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4554000 USD
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0 USD
CY2015 us-gaap Current Federal Tax Expense Benefit
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2094000 USD
CY2016 us-gaap Current Federal Tax Expense Benefit
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0 USD
CY2015 us-gaap Current Income Tax Expense Benefit
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3803000 USD
CY2016 us-gaap Current Income Tax Expense Benefit
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0 USD
CY2015 us-gaap Current State And Local Tax Expense Benefit
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1709000 USD
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2870000 USD
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1832000 USD
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30000 USD
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3160000 USD
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25124000 USD
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34153000 USD
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0 USD
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500000 USD
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5401000 USD
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0 USD
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1881000 USD
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3.49
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0.31
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0 USD
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117000 USD
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0.0223
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0.1835
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0.35
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0.35
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0.35
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-0.2663
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-0.2702
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-0.1630
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-0.0551
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0.0000
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0.0153
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0.0316
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0.0000
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0.0785
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0 USD
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0.0000
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0.0000
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0.0115
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0.0000
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0.0368
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-0.0205
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0.0677
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-0.0158
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0 USD
CY2015 us-gaap Excess Tax Benefit From Share Based Compensation Financing Activities
ExcessTaxBenefitFromShareBasedCompensationFinancingActivities
2425000 USD
CY2016 us-gaap Excess Tax Benefit From Share Based Compensation Financing Activities
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CY2014 us-gaap Fair Value Adjustment Of Warrants
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23786000 USD
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33307000 USD
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-1655000 USD
CY2015 us-gaap Fair Value Assumptions Expected Dividend Rate
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0
CY2016 us-gaap Fair Value Assumptions Expected Dividend Rate
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0
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17560000 USD
CY2016Q4 us-gaap Finite Lived Intangible Assets Accumulated Amortization
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33497000 USD
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72148000 USD
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16879000 USD
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16879000 USD
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16879000 USD
CY2016Q4 us-gaap Finite Lived Intangible Assets Amortization Expense Year Three
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16879000 USD
CY2016Q4 us-gaap Finite Lived Intangible Assets Amortization Expense Year Two
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16879000 USD
CY2015 us-gaap Foreign Currency Transaction Gain Loss Before Tax
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140004000 USD
CY2016 us-gaap Foreign Currency Transaction Gain Loss Before Tax
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0 USD
CY2014 us-gaap Foreign Currency Transaction Gain Loss Realized
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0 USD
CY2015 us-gaap Foreign Currency Transaction Gain Loss Realized
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-40000 USD
CY2016 us-gaap Foreign Currency Transaction Gain Loss Realized
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93000 USD
CY2015 us-gaap Gain Loss On Disposition Of Assets1
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900000 USD
CY2014 us-gaap Gain Loss On Sale Of Property Plant Equipment
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0 USD
CY2015 us-gaap Gain Loss On Sale Of Property Plant Equipment
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-112000 USD
CY2016 us-gaap Gain Loss On Sale Of Property Plant Equipment
GainLossOnSaleOfPropertyPlantEquipment
-62000 USD
CY2014 us-gaap Gain Loss Related To Litigation Settlement
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0 USD
CY2015 us-gaap Gain Loss Related To Litigation Settlement
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15500000 USD
CY2016 us-gaap Gain Loss Related To Litigation Settlement
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0 USD
CY2014 us-gaap Gains Losses On Extinguishment Of Debt
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0 USD
CY2015 us-gaap Gains Losses On Extinguishment Of Debt
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-4151000 USD
CY2016 us-gaap Gains Losses On Extinguishment Of Debt
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0 USD
CY2015Q4 us-gaap Goodwill
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936000 USD
CY2016Q4 us-gaap Goodwill
Goodwill
936000 USD
CY2014 us-gaap Goodwill Impairment Loss
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0 USD
CY2015 us-gaap Goodwill Impairment Loss
GoodwillImpairmentLoss
0 USD
CY2016 us-gaap Goodwill Impairment Loss
GoodwillImpairmentLoss
0 USD
CY2014 us-gaap Impairment Of Intangible Assets Excluding Goodwill
ImpairmentOfIntangibleAssetsExcludingGoodwill
0 USD
CY2015 us-gaap Impairment Of Intangible Assets Excluding Goodwill
ImpairmentOfIntangibleAssetsExcludingGoodwill
4700000 USD
CY2016 us-gaap Impairment Of Intangible Assets Excluding Goodwill
ImpairmentOfIntangibleAssetsExcludingGoodwill
0 USD
CY2014 us-gaap Impairment Of Intangible Assets Finitelived
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CY2016 us-gaap Impairment Of Intangible Assets Finitelived
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300000 USD
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8000 USD
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400000 USD
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663000 USD
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0 USD
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4016000 USD
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428000 USD
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2587000 USD
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100000 USD
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200000 USD
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500000 USD
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1000000 USD
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17372000 USD
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24068000 USD
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CY2016 us-gaap Nature Of Operations
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<div style="font-family:Times New Roman;font-size:10pt;"><div style="line-height:120%;padding-bottom:13px;padding-top:12px;font-size:13pt;"><font style="font-family:Arial;font-size:13pt;color:#4c4c4c;font-style:normal;font-weight:bold;text-decoration:none;">DESCRIPTION OF BUSINESS</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:16px;font-size:12pt;"><font style="font-family:Arial;font-size:12pt;color:#006ebf;font-style:normal;font-weight:bold;text-decoration:none;">Organization and Description of Business</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:4px;text-align:justify;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">Retrophin, Inc. (&#8220;we&#8221;, &#8220;our&#8221;, &#8220;us&#8221;, &#8220;Retrophin&#8221; and the &#8220;Company&#8221;) refers to Retrophin, Inc., a Delaware corporation, as well as our direct and indirect subsidiaries. Retrophin is a fully integrated biopharmaceutical company headquartered in San Diego, California focused on the development, acquisition and commercialization of therapies for the treatment of serious or rare diseases. We regularly evaluate and, where appropriate, act on opportunities to expand our product pipeline through licenses and acquisitions of products in areas that will serve patients with serious or rare diseases and that we believe offer attractive growth characteristics. </font></div><div style="line-height:120%;padding-bottom:8px;padding-top:12px;font-size:10.5pt;"><font style="font-family:Arial;font-size:10.5pt;color:#666666;font-style:italic;font-weight:bold;text-decoration:none;">We are currently developing the following pipeline products:</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:4px;text-align:justify;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">Sparsentan is an investigational therapeutic agent which acts as both a potent ARB, as well as a selective ERA, with in vitro selectivity toward endothelin receptor type A. The Company has secured a license to sparsentan from Ligand Pharmaceuticals, Inc. and Bristol-Myers Squibb Company (who referred to it as DARA). The Company is developing sparsentan as a treatment for FSGS, which is a leading cause of end-stage renal disease and NS. Sparsentan was granted orphan drug designation in the United States and the European Union in January 2015 and November 2015, respectively. In the third quarter of 2016, the Company announced positive top-line data from the Phase 2 DUET study of sparsentan for the treatment of FSGS. </font><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">In early 2017, we had</font><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;font-weight:bold;"> </font><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">an End of Phase 2 meeting with the FDA regarding the regulatory pathway for sparsentan as a treatment for FSGS.&#160; Following the meeting and our receipt of confirmatory meeting minutes, we announced our plans to initiate a single Phase 3 clinical trial to serve as the basis of a New Drug Application ("NDA") filing for sparsentan for the treatment of FSGS.</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:4px;text-align:justify;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">Fosmetpantotenate</font><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">, also known as RE-024, a novel small molecule, is being developed as a potential treatment for pantothenate kinase-associated neurodegeneration (&#8220;PKAN&#8221;). PKAN is a genetic neurodegenerative disorder that is typically diagnosed in the first decade of life. Consequences of PKAN include parkinsonism, dystonia, and other severe systemic manifestations. </font><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">Fosmetpantotenate (RE-024) is a phosphopantothenate replacement therapy that aims to restore levels of this key substrate in PKAN patients. Certain international health regulators have approved the initiation of dosing fosmetpantotenate (RE-024) in PKAN patients under physician-initiated studies in accordance with local regulations in their respective countries. The Company filed a U.S. IND for fosmetpantotenate (RE-024) with the FDA in the first quarter of 2015 to support the commencement of a Company-sponsored Phase 1 study, which was successfully completed during 2015. The FDA granted fosmetpantotenate (RE-024) orphan drug designation in May 2015 and fast track designation in June 2015. In February, 2016, the Company announced fosmetpantotenate (RE-024) was granted orphan drug designation by the European Commission. In November, 2016, the Company announced that it had reached an agreement with the&#160;FDA under the Special Protocol Assessment (SPA) process for a Phase 3 clinical trial evaluating fosmetpantotenate (RE-024) for PKAN. The Company expect to begin dosing patients in this Phase 3 clinical trial in the coming months. The Company continues discussions with the EMA regarding the initiation of a potential registration-enabling efficacy trial in PKAN patients.</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:4px;text-align:left;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">Tetracosactide zinc (RE-034) is a synthetic hormone analog of the first 24 amino acids of the 39 amino acids contained in adrenocorticotropic hormone ("ACTH") incorporated into a novel formulation developed by us. Tetracosactide zinc (RE-034) exhibits similar physiological actions as endogenous ACTH by binding to all five melanocortin receptors (pan-MCR), resulting in its anti-inflammatory and immunomodulatory effects. The Company successfully manufactured tetracosactide zinc (RE-034) at proof-of-concept scale using a novel formulation process that allows modulation of the release of the active ingredient from the site of administration. The Company decided to focus our further efforts on this program toward an external partnership and out-licensing opportunities. </font></div><div style="line-height:120%;padding-bottom:8px;padding-top:4px;text-align:left;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">Liquid ursodeoxycholic acid ("L-UDCA") is a liquid formulation of ursodeoxycholic acid being developed for the treatment of a rare liver disease called primary biliary cholangitis ("PBC"). We obtained L-UDCA during 2016 with the intention of making L-UDCA commercially available to the subset of PBC patients who have difficulty swallowing. </font></div><div style="line-height:120%;padding-bottom:8px;padding-top:12px;font-size:10.5pt;"><font style="font-family:Arial;font-size:10.5pt;color:#666666;font-style:italic;font-weight:bold;text-decoration:none;">We currently sell the following </font><font style="font-family:Arial;font-size:10.5pt;color:#666666;font-style:italic;font-weight:bold;text-decoration:none;">three</font><font style="font-family:Arial;font-size:10.5pt;color:#666666;font-style:italic;font-weight:bold;text-decoration:none;"> products:</font></div><table cellpadding="0" cellspacing="0" style="padding-top:4px;padding-bottom:8px;font-family:Times New Roman; font-size:10pt;"><tr><td style="width:48px;" rowspan="1" colspan="1"></td><td rowspan="1" colspan="1"></td></tr><tr><td style="vertical-align:top" rowspan="1" colspan="1"><div style="line-height:120%;font-size:9.5pt;padding-left:24px;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">&#8226;</font></div></td><td style="vertical-align:top;" rowspan="1" colspan="1"><div style="line-height:120%;text-align:justify;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">Chenodal (chenodiol tablets) is approved in the United States for the treatment of patients suffering from gallstones in whom surgery poses an unacceptable health risk due to disease or advanced age. Chenodal has been the standard of care for CTX patients for more than three decades and the Company is currently pursuing adding this indication to the label.</font></div></td></tr></table><table cellpadding="0" cellspacing="0" style="padding-top:4px;padding-bottom:8px;font-family:Times New Roman; font-size:10pt;"><tr><td style="width:48px;" rowspan="1" colspan="1"></td><td rowspan="1" colspan="1"></td></tr><tr><td style="vertical-align:top" rowspan="1" colspan="1"><div style="line-height:120%;font-size:9.5pt;padding-left:24px;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">&#8226;</font></div></td><td style="vertical-align:top;" rowspan="1" colspan="1"><div style="line-height:120%;text-align:justify;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">Cholbam (cholic acid capsules) is approved in the United States for the treatment of bile acid synthesis disorders due to single enzyme defects and is further indicated for adjunctive treatment of patients with peroxisomal disorders.</font></div></td></tr></table><table cellpadding="0" cellspacing="0" style="padding-top:4px;padding-bottom:8px;font-family:Times New Roman; font-size:10pt;"><tr><td style="width:48px;" rowspan="1" colspan="1"></td><td rowspan="1" colspan="1"></td></tr><tr><td style="vertical-align:top" rowspan="1" colspan="1"><div style="line-height:120%;font-size:9.5pt;padding-left:24px;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">&#8226;</font></div></td><td style="vertical-align:top;" rowspan="1" colspan="1"><div style="line-height:120%;text-align:justify;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">Thiola (tiopronin tablets) is approved in the United States for the </font><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">prevention of cystine (kidney) stone formation in patients with severe homozygous cystinuria.</font></div></td></tr></table></div>
CY2016 us-gaap Prior Period Reclassification Adjustment Description
PriorPeriodReclassificationAdjustmentDescription
<div style="font-family:Times New Roman;font-size:10pt;"><div style="line-height:120%;padding-bottom:8px;padding-top:12px;text-align:justify;font-size:10pt;"><font style="font-family:Arial Narrow;font-size:10pt;color:#006ebf;font-style:normal;font-weight:bold;text-decoration:none;">Reclassifications</font><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;font-style:italic;">&#160;</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:4px;text-align:justify;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">Certain reclassifications have been made to the prior year financial statements in order to conform to the current year&#8217;s presentation.</font></div></div>
CY2016 us-gaap Revenue Recognition Services Licensing Fees
RevenueRecognitionServicesLicensingFees
<div style="font-family:Times New Roman;font-size:10pt;"><div style="line-height:120%;padding-bottom:8px;padding-top:12px;text-align:justify;font-size:10pt;"><font style="font-family:Arial Narrow;font-size:10pt;color:#006ebf;font-style:normal;font-weight:bold;text-decoration:none;">Patents</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:4px;text-align:justify;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">The Company expenses external costs, such as filing fees and associated attorney fees, incurred to obtain issued patents and patent applications pending. The Company also expenses costs associated with maintaining and defending patents subsequent to their issuance in the period incurred.</font></div></div>
CY2016 us-gaap Use Of Estimates
UseOfEstimates
<div style="font-family:Times New Roman;font-size:10pt;"><div style="line-height:120%;padding-bottom:8px;padding-top:12px;font-size:10pt;"><font style="font-family:Arial Narrow;font-size:10pt;color:#006ebf;font-style:normal;font-weight:bold;text-decoration:none;">Use of Estimates</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:4px;text-align:justify;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">In preparing financial statements in conformity with U.S. GAAP, management is required to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements, as well as the reported amounts of expenses during the reporting period. Due to inherent uncertainty involved in making estimates, actual results reported in future periods may be affected by changes in these estimates. On an ongoing basis, the Company evaluates its estimates and assumptions. These estimates and assumptions include revenue recognition, valuing equity securities in share-based payments, estimating fair value of equity instruments recorded as derivative liabilities, estimating the fair value of net assets acquired in business combinations, estimating the useful lives of depreciable and amortizable assets, goodwill impairment, estimating of contingent consideration, estimating of valuation allowances and uncertain tax positions, and estimating the fair value of long-lived assets to assess whether impairment charges may apply.</font></div></div>

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