2018 Q3 Form 10-Q Financial Statement
#000143853318000028 Filed on August 03, 2018
Income Statement
Concept | 2018 Q3 | 2018 Q2 | 2017 Q2 |
---|---|---|---|
Revenue | $40.71M | $41.34M | $38.80M |
YoY Change | 101665.0% | 6.54% | 16.48% |
Cost Of Revenue | $1.133M | $1.178M | $797.0K |
YoY Change | 22.49% | 47.8% | -21.94% |
Gross Profit | $39.57M | $40.16M | $38.00M |
YoY Change | -4571.53% | 5.67% | 17.69% |
Gross Profit Margin | 97.22% | 97.15% | 97.95% |
Selling, General & Admin | $26.11M | $25.10M | $28.84M |
YoY Change | 5.05% | -12.95% | 24.26% |
% of Gross Profit | 65.97% | 62.5% | 75.88% |
Research & Development | $32.45M | $34.46M | $19.48M |
YoY Change | 65.47% | 76.88% | 10.22% |
% of Gross Profit | 82.0% | 85.81% | 51.26% |
Depreciation & Amortization | $4.800M | $4.640M | $4.440M |
YoY Change | 3.9% | 4.5% | 11.84% |
% of Gross Profit | 12.13% | 11.55% | 11.68% |
Operating Expenses | $76.29M | $62.90M | $52.40M |
YoY Change | 49.74% | 20.04% | 17.25% |
Operating Profit | -$35.58M | -$21.56M | -$13.60M |
YoY Change | 235.44% | 58.55% | 19.5% |
Interest Expense | -$2.533M | -$1.057M | -$658.0K |
YoY Change | 283.79% | 60.64% | 347.62% |
% of Operating Profit | |||
Other Income/Expense, Net | -$18.52M | -$602.0K | -$1.556M |
YoY Change | 120.22% | -61.31% | -116.53% |
Pretax Income | -$54.10M | -$22.16M | -$15.15M |
YoY Change | 184.49% | 46.25% | -27.13% |
Income Tax | $415.0K | $167.0K | -$1.925M |
% Of Pretax Income | |||
Net Earnings | -$54.52M | -$22.33M | -$13.23M |
YoY Change | 206.37% | 68.79% | -1.3% |
Net Earnings / Revenue | -133.93% | -54.02% | -34.1% |
Basic Earnings Per Share | -$1.34 | -$0.56 | -$0.34 |
Diluted Earnings Per Share | -$1.34 | -$0.56 | -$0.34 |
COMMON SHARES | |||
Basic Shares Outstanding | 40.43M shares | 39.94M shares | 39.04M shares |
Diluted Shares Outstanding | 39.04M shares |
Balance Sheet
Concept | 2018 Q3 | 2018 Q2 | 2017 Q2 |
---|---|---|---|
SHORT-TERM ASSETS | |||
Cash & Short-Term Investments | $350.9M | $255.7M | $296.0M |
YoY Change | 15.47% | -13.61% | 33.62% |
Cash & Equivalents | $154.8M | $89.31M | $89.27M |
Short-Term Investments | $196.1M | $166.4M | $206.7M |
Other Short-Term Assets | $5.600M | $5.500M | $6.000M |
YoY Change | 115.38% | -8.33% | -49.58% |
Inventory | $5.129M | $5.388M | $4.369M |
Prepaid Expenses | |||
Receivables | $13.45M | $12.32M | $13.32M |
Other Receivables | $0.00 | $0.00 | $0.00 |
Total Short-Term Assets | $503.0M | $278.9M | $319.7M |
YoY Change | 54.6% | -12.75% | 6.5% |
LONG-TERM ASSETS | |||
Property, Plant & Equipment | $3.323M | $3.455M | $2.540M |
YoY Change | 22.3% | 36.02% | 566.67% |
Goodwill | $936.0K | $936.0K | $936.0K |
YoY Change | 0.0% | 0.0% | 0.0% |
Intangibles | |||
YoY Change | |||
Long-Term Investments | $15.00M | $15.00M | |
YoY Change | |||
Other Assets | $7.393M | $5.351M | $3.628M |
YoY Change | 4.11% | 47.49% | 95.16% |
Total Long-Term Assets | $213.2M | $212.2M | $187.5M |
YoY Change | 9.24% | 13.2% | -19.82% |
TOTAL ASSETS | |||
Total Short-Term Assets | $503.0M | $278.9M | $319.7M |
Total Long-Term Assets | $213.2M | $212.2M | $187.5M |
Total Assets | $716.2M | $491.1M | $507.1M |
YoY Change | 37.59% | -3.15% | -5.03% |
SHORT-TERM LIABILITIES | |||
YoY Change | |||
Accounts Payable | $9.314M | $7.847M | $9.076M |
YoY Change | 26.38% | -13.54% | 44.41% |
Accrued Expenses | $43.35M | $35.27M | $27.60M |
YoY Change | 34.4% | 27.8% | 19.16% |
Deferred Revenue | |||
YoY Change | |||
Short-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Long-Term Debt Due | $22.40M | $45.40M | |
YoY Change | |||
Total Short-Term Liabilities | $99.87M | $103.5M | $79.63M |
YoY Change | 19.03% | 29.98% | -0.55% |
LONG-TERM LIABILITIES | |||
Long-Term Debt | $192.8M | $0.00 | $44.70M |
YoY Change | 329.4% | -100.0% | 1.36% |
Other Long-Term Liabilities | $4.885M | $4.880M | $3.851M |
YoY Change | 28.28% | 26.72% | 51.14% |
Total Long-Term Liabilities | $4.885M | $4.880M | $3.851M |
YoY Change | 28.28% | 26.72% | 51.14% |
TOTAL LIABILITIES | |||
Total Short-Term Liabilities | $99.87M | $103.5M | $79.63M |
Total Long-Term Liabilities | $4.885M | $4.880M | $3.851M |
Total Liabilities | $397.1M | $203.2M | $211.3M |
YoY Change | 83.86% | -3.86% | -3.78% |
SHAREHOLDERS EQUITY | |||
Retained Earnings | -$262.6M | -$208.0M | -$142.2M |
YoY Change | 64.06% | 46.26% | 111.23% |
Common Stock | $582.7M | $497.2M | $438.6M |
YoY Change | 25.27% | 13.35% | 14.92% |
Preferred Stock | |||
YoY Change | |||
Treasury Stock (at cost) | |||
YoY Change | |||
Treasury Stock Shares | |||
Shareholders Equity | $319.1M | $288.0M | $295.8M |
YoY Change | |||
Total Liabilities & Shareholders Equity | $716.2M | $491.1M | $507.1M |
YoY Change | 37.59% | -3.15% | -5.03% |
Cashflow Statement
Concept | 2018 Q3 | 2018 Q2 | 2017 Q2 |
---|---|---|---|
OPERATING ACTIVITIES | |||
Net Income | -$54.52M | -$22.33M | -$13.23M |
YoY Change | 206.37% | 68.79% | -1.3% |
Depreciation, Depletion And Amortization | $4.800M | $4.640M | $4.440M |
YoY Change | 3.9% | 4.5% | 11.84% |
Cash From Operating Activities | -$3.900M | -$2.760M | $5.470M |
YoY Change | -162.9% | -150.46% | 37.09% |
INVESTING ACTIVITIES | |||
Capital Expenditures | -$3.850M | -$3.730M | -$3.010M |
YoY Change | 2.94% | 23.92% | 30.3% |
Acquisitions | |||
YoY Change | |||
Other Investing Activities | -$157.7M | $31.65M | $46.79M |
YoY Change | -10340.26% | -32.36% | -2463.13% |
Cash From Investing Activities | -$161.6M | $27.91M | $43.76M |
YoY Change | 7310.55% | -36.22% | -1120.05% |
FINANCING ACTIVITIES | |||
Cash Dividend Paid | |||
YoY Change | |||
Common Stock Issuance & Retirement, Net | |||
YoY Change | |||
Debt Paid & Issued, Net | |||
YoY Change | |||
Cash From Financing Activities | 231.0M | 3.080M | -1.900M |
YoY Change | 3861.58% | -262.11% | -0.52% |
NET CHANGE | |||
Cash From Operating Activities | -3.900M | -2.760M | 5.470M |
Cash From Investing Activities | -161.6M | 27.91M | 43.76M |
Cash From Financing Activities | 231.0M | 3.080M | -1.900M |
Net Change In Cash | 65.51M | 28.23M | 47.33M |
YoY Change | 565.08% | -40.35% | -2241.63% |
FREE CASH FLOW | |||
Cash From Operating Activities | -$3.900M | -$2.760M | $5.470M |
Capital Expenditures | -$3.850M | -$3.730M | -$3.010M |
Free Cash Flow | -$50.00K | $970.0K | $8.480M |
YoY Change | -100.5% | -88.56% | 34.6% |
Facts In Submission
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---|---|---|---|---|
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|
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2018 | ||
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2018-06-30 | ||
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48264000 | USD | |
us-gaap |
Cash And Cash Equivalents Period Increase Decrease
CashAndCashEquivalentsPeriodIncreaseDecrease
|
-10089000 | USD | |
CY2017Q4 | us-gaap |
Class Of Warrant Or Right Outstanding
ClassOfWarrantOrRightOutstanding
|
1159424 | shares |
CY2018Q2 | us-gaap |
Class Of Warrant Or Right Outstanding
ClassOfWarrantOrRightOutstanding
|
735365 | shares |
CY2017Q4 | us-gaap |
Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
|
0.0001 | |
CY2018Q2 | us-gaap |
Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
|
0.0001 | |
CY2017Q4 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
100000000 | shares |
CY2018Q2 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
100000000 | shares |
CY2017Q4 | us-gaap |
Common Stock Shares Issued
CommonStockSharesIssued
|
39373745 | shares |
CY2018Q2 | us-gaap |
Common Stock Shares Issued
CommonStockSharesIssued
|
40370521 | shares |
CY2017Q4 | us-gaap |
Common Stock Shares Outstanding
CommonStockSharesOutstanding
|
39373745 | shares |
CY2018Q2 | us-gaap |
Common Stock Shares Outstanding
CommonStockSharesOutstanding
|
40370521 | shares |
CY2017Q4 | us-gaap |
Common Stock Value
CommonStockValue
|
4000 | USD |
CY2018Q2 | us-gaap |
Common Stock Value
CommonStockValue
|
4000 | USD |
CY2017Q2 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-13385000 | USD |
us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-24405000 | USD | |
CY2018Q2 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-21952000 | USD |
us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-40844000 | USD | |
CY2017Q4 | us-gaap |
Convertible Debt Current
ConvertibleDebtCurrent
|
0 | USD |
CY2018Q2 | us-gaap |
Convertible Debt Current
ConvertibleDebtCurrent
|
45401000 | USD |
CY2018Q2 | us-gaap |
Convertible Debt Fair Value Disclosures
ConvertibleDebtFairValueDisclosures
|
74000000 | USD |
CY2017Q4 | us-gaap |
Convertible Debt Noncurrent
ConvertibleDebtNoncurrent
|
45077000 | USD |
CY2018Q2 | us-gaap |
Convertible Debt Noncurrent
ConvertibleDebtNoncurrent
|
0 | USD |
CY2017Q2 | us-gaap |
Cost Of Goods Sold
CostOfGoodsSold
|
797000 | USD |
CY2017Q4 | us-gaap |
Derivative Liabilities Current
DerivativeLiabilitiesCurrent
|
15710000 | USD |
CY2018Q2 | us-gaap |
Derivative Liabilities Current
DerivativeLiabilitiesCurrent
|
0 | USD |
CY2018Q2 | us-gaap |
Cost Of Goods Sold
CostOfGoodsSold
|
1178000 | USD |
us-gaap |
Cost Of Goods Sold
CostOfGoodsSold
|
2791000 | USD | |
us-gaap |
Deferred Income Tax Expense Benefit
DeferredIncomeTaxExpenseBenefit
|
-5420000 | USD | |
CY2017Q2 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.34 | |
us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.63 | ||
CY2018Q2 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.56 | |
us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-1.03 | ||
us-gaap |
Effect Of Exchange Rate On Cash And Cash Equivalents
EffectOfExchangeRateOnCashAndCashEquivalents
|
63000 | USD | |
us-gaap |
Effect Of Exchange Rate On Cash And Cash Equivalents
EffectOfExchangeRateOnCashAndCashEquivalents
|
-34000 | USD | |
CY2017Q2 | us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
0.127 | |
us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
0.141 | ||
CY2018Q2 | us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
-0.008 | |
us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
-0.010 | ||
CY2017Q4 | us-gaap |
Equity Method Investments
EquityMethodInvestments
|
0 | USD |
CY2018Q2 | us-gaap |
Equity Method Investments
EquityMethodInvestments
|
15000000 | USD |
CY2018Q2 | us-gaap |
Equity Method Investments
EquityMethodInvestments
|
15000000 | USD |
CY2017Q2 | us-gaap |
Fair Value Adjustment Of Warrants
FairValueAdjustmentOfWarrants
|
1300000 | USD |
CY2017Q2 | us-gaap |
Fair Value Adjustment Of Warrants
FairValueAdjustmentOfWarrants
|
1280000 | USD |
us-gaap |
Fair Value Adjustment Of Warrants
FairValueAdjustmentOfWarrants
|
20000 | USD | |
CY2018Q2 | us-gaap |
Fair Value Adjustment Of Warrants
FairValueAdjustmentOfWarrants
|
0 | USD |
us-gaap |
Fair Value Adjustment Of Warrants
FairValueAdjustmentOfWarrants
|
0 | USD | |
CY2017Q4 | us-gaap |
Finite Lived Intangible Assets Accumulated Amortization
FiniteLivedIntangibleAssetsAccumulatedAmortization
|
51046000 | USD |
CY2018Q2 | us-gaap |
Finite Lived Intangible Assets Accumulated Amortization
FiniteLivedIntangibleAssetsAccumulatedAmortization
|
59672000 | USD |
CY2017Q4 | us-gaap |
Finite Lived Intangible Assets Gross
FiniteLivedIntangibleAssetsGross
|
235863000 | USD |
CY2018Q2 | us-gaap |
Finite Lived Intangible Assets Gross
FiniteLivedIntangibleAssetsGross
|
247157000 | USD |
CY2017Q4 | us-gaap |
Finite Lived Intangible Assets Net
FiniteLivedIntangibleAssetsNet
|
184817000 | USD |
CY2018Q2 | us-gaap |
Finite Lived Intangible Assets Net
FiniteLivedIntangibleAssetsNet
|
187485000 | USD |
us-gaap |
Foreign Currency Transaction Gain Loss Before Tax
ForeignCurrencyTransactionGainLossBeforeTax
|
559000 | USD | |
us-gaap |
Foreign Currency Transaction Gain Loss Before Tax
ForeignCurrencyTransactionGainLossBeforeTax
|
-214000 | USD | |
CY2017Q2 | us-gaap |
Foreign Currency Transaction Gain Loss Realized
ForeignCurrencyTransactionGainLossRealized
|
-183000 | USD |
us-gaap |
Foreign Currency Transaction Gain Loss Realized
ForeignCurrencyTransactionGainLossRealized
|
-259000 | USD | |
CY2018Q2 | us-gaap |
Foreign Currency Transaction Gain Loss Realized
ForeignCurrencyTransactionGainLossRealized
|
2000 | USD |
us-gaap |
Foreign Currency Transaction Gain Loss Realized
ForeignCurrencyTransactionGainLossRealized
|
24000 | USD | |
us-gaap |
Gain Loss On Disposition Of Assets1
GainLossOnDispositionOfAssets1
|
-305000 | USD | |
us-gaap |
Gain Loss On Disposition Of Assets1
GainLossOnDispositionOfAssets1
|
0 | USD | |
CY2017Q4 | us-gaap |
Goodwill
Goodwill
|
936000 | USD |
CY2018Q2 | us-gaap |
Goodwill
Goodwill
|
936000 | USD |
CY2017Q2 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-15154000 | USD |
us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-28308000 | USD | |
CY2018Q2 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-22162000 | USD |
us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-40311000 | USD | |
CY2018Q2 | us-gaap |
Inventory Finished Goods Net Of Reserves
InventoryFinishedGoodsNetOfReserves
|
1677000 | USD |
CY2017Q2 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
-1925000 | USD |
us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
-3989000 | USD | |
CY2018Q2 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
200000 | USD |
CY2018Q2 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
167000 | USD |
us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
400000 | USD | |
us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
396000 | USD | |
us-gaap |
Increase Decrease In Accounts Payable And Accrued Liabilities
IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
|
-3458000 | USD | |
us-gaap |
Increase Decrease In Accounts Payable And Accrued Liabilities
IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
|
-2811000 | USD | |
us-gaap |
Increase Decrease In Accounts Receivable
IncreaseDecreaseInAccountsReceivable
|
-4685000 | USD | |
us-gaap |
Increase Decrease In Accounts Receivable
IncreaseDecreaseInAccountsReceivable
|
-1431000 | USD | |
us-gaap |
Increase Decrease In Inventories
IncreaseDecreaseInInventories
|
212000 | USD | |
us-gaap |
Increase Decrease In Inventories
IncreaseDecreaseInInventories
|
433000 | USD | |
us-gaap |
Increase Decrease In Other Operating Assets
IncreaseDecreaseInOtherOperatingAssets
|
12000 | USD | |
us-gaap |
Increase Decrease In Other Operating Assets
IncreaseDecreaseInOtherOperatingAssets
|
-637000 | USD | |
us-gaap |
Increase Decrease In Other Operating Liabilities
IncreaseDecreaseInOtherOperatingLiabilities
|
-45000 | USD | |
us-gaap |
Increase Decrease In Other Operating Liabilities
IncreaseDecreaseInOtherOperatingLiabilities
|
2485000 | USD | |
CY2018Q2 | us-gaap |
Insurance Settlements Receivable
InsuranceSettlementsReceivable
|
562500 | USD |
CY2017Q2 | us-gaap |
Interest Income Expense Nonoperating Net
InterestIncomeExpenseNonoperatingNet
|
-658000 | USD |
us-gaap |
Interest Income Expense Nonoperating Net
InterestIncomeExpenseNonoperatingNet
|
-790000 | USD | |
CY2018Q2 | us-gaap |
Interest Income Expense Nonoperating Net
InterestIncomeExpenseNonoperatingNet
|
-199000 | USD |
CY2017Q4 | us-gaap |
Inventory Net
InventoryNet
|
5351000 | USD |
us-gaap |
Interest Income Expense Nonoperating Net
InterestIncomeExpenseNonoperatingNet
|
-557000 | USD | |
CY2017Q4 | us-gaap |
Inventory Finished Goods Net Of Reserves
InventoryFinishedGoodsNetOfReserves
|
1916000 | USD |
CY2017Q4 | us-gaap |
Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
|
520346000 | USD |
CY2017Q4 | us-gaap |
Liabilities Current
LiabilitiesCurrent
|
85668000 | USD |
CY2018Q2 | us-gaap |
Liabilities Current
LiabilitiesCurrent
|
103497000 | USD |
CY2017Q4 | us-gaap |
Marketable Securities
MarketableSecurities
|
201236000 | USD |
CY2018Q2 | us-gaap |
Marketable Securities
MarketableSecurities
|
166400000 | USD |
CY2018Q2 | us-gaap |
Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
|
491144000 | USD |
CY2018Q2 | us-gaap |
Marketable Securities
MarketableSecurities
|
166381000 | USD |
us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
-1751000 | USD | |
CY2018Q2 | us-gaap |
Inventory Net
InventoryNet
|
5388000 | USD |
CY2017Q4 | us-gaap |
Inventory Raw Materials Net Of Reserves
InventoryRawMaterialsNetOfReserves
|
3435000 | USD |
CY2018Q2 | us-gaap |
Inventory Raw Materials Net Of Reserves
InventoryRawMaterialsNetOfReserves
|
3711000 | USD |
CY2017Q4 | us-gaap |
Inventory Valuation Reserves
InventoryValuationReserves
|
700000 | USD |
CY2018Q2 | us-gaap |
Inventory Valuation Reserves
InventoryValuationReserves
|
1400000 | USD |
CY2017Q2 | us-gaap |
Legal Fees
LegalFees
|
2000000 | USD |
us-gaap |
Legal Fees
LegalFees
|
2000000 | USD | |
CY2018Q2 | us-gaap |
Legal Fees
LegalFees
|
0 | USD |
us-gaap |
Legal Fees
LegalFees
|
0 | USD | |
CY2017Q4 | us-gaap |
Liabilities
Liabilities
|
227212000 | USD |
CY2018Q2 | us-gaap |
Liabilities
Liabilities
|
203155000 | USD |
us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
47893000 | USD | |
us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
7056000 | USD | |
us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
2059000 | USD | |
us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-17494000 | USD | |
CY2017Q2 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-13229000 | USD |
us-gaap |
Net Income Loss
NetIncomeLoss
|
-24319000 | USD | |
CY2018Q2 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-22329000 | USD |
us-gaap |
Net Income Loss
NetIncomeLoss
|
-40707000 | USD | |
CY2017Q2 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
-1556000 | USD |
us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
-302000 | USD | |
CY2018Q2 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
-602000 | USD |
us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
-839000 | USD | |
CY2017Q2 | us-gaap |
Operating Expenses
OperatingExpenses
|
52398000 | USD |
us-gaap |
Operating Expenses
OperatingExpenses
|
100426000 | USD | |
CY2018Q2 | us-gaap |
Operating Expenses
OperatingExpenses
|
62897000 | USD |
us-gaap |
Operating Expenses
OperatingExpenses
|
119241000 | USD | |
CY2017Q2 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-13598000 | USD |
us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-28006000 | USD | |
CY2018Q2 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-21560000 | USD |
us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-39472000 | USD | |
CY2017Q4 | us-gaap |
Other Assets Noncurrent
OtherAssetsNoncurrent
|
5556000 | USD |
CY2018Q2 | us-gaap |
Other Assets Noncurrent
OtherAssetsNoncurrent
|
5351000 | USD |
CY2017Q2 | us-gaap |
Other Comprehensive Income Availableforsale Securities Adjustment Net Of Tax Portion Attributable To Parent
OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent
|
27000 | USD |
us-gaap |
Other Comprehensive Income Availableforsale Securities Adjustment Net Of Tax Portion Attributable To Parent
OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent
|
173000 | USD | |
CY2018Q2 | us-gaap |
Other Comprehensive Income Availableforsale Securities Adjustment Net Of Tax Portion Attributable To Parent
OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent
|
375000 | USD |
us-gaap |
Other Comprehensive Income Availableforsale Securities Adjustment Net Of Tax Portion Attributable To Parent
OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent
|
-161000 | USD | |
CY2018Q2 | us-gaap |
Preferred Stock Shares Issued
PreferredStockSharesIssued
|
0 | shares |
CY2017Q4 | us-gaap |
Preferred Stock Shares Outstanding
PreferredStockSharesOutstanding
|
0 | shares |
CY2018Q2 | us-gaap |
Preferred Stock Shares Outstanding
PreferredStockSharesOutstanding
|
0 | shares |
CY2017Q4 | us-gaap |
Preferred Stock Value
PreferredStockValue
|
0 | USD |
CY2018Q2 | us-gaap |
Preferred Stock Value
PreferredStockValue
|
0 | USD |
CY2017Q4 | us-gaap |
Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
|
3112000 | USD |
CY2017Q4 | us-gaap |
Other Liabilities Current
OtherLiabilitiesCurrent
|
3902000 | USD |
CY2018Q2 | us-gaap |
Other Liabilities Current
OtherLiabilitiesCurrent
|
3479000 | USD |
CY2017Q4 | us-gaap |
Other Liabilities Noncurrent
OtherLiabilitiesNoncurrent
|
2472000 | USD |
CY2018Q2 | us-gaap |
Other Liabilities Noncurrent
OtherLiabilitiesNoncurrent
|
4880000 | USD |
us-gaap |
Other Noncash Income Expense
OtherNoncashIncomeExpense
|
-197000 | USD | |
us-gaap |
Other Noncash Income Expense
OtherNoncashIncomeExpense
|
-537000 | USD | |
CY2017Q2 | us-gaap |
Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
|
382000 | USD |
us-gaap |
Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
|
508000 | USD | |
CY2018Q2 | us-gaap |
Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
|
-403000 | USD |
us-gaap |
Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
|
-282000 | USD | |
us-gaap |
Payment For Contingent Consideration Liability Financing Activities
PaymentForContingentConsiderationLiabilityFinancingActivities
|
3254000 | USD | |
us-gaap |
Payment For Contingent Consideration Liability Financing Activities
PaymentForContingentConsiderationLiabilityFinancingActivities
|
7947000 | USD | |
us-gaap |
Payments To Acquire Available For Sale Securities
PaymentsToAcquireAvailableForSaleSecurities
|
36213000 | USD | |
us-gaap |
Payments To Acquire Available For Sale Securities
PaymentsToAcquireAvailableForSaleSecurities
|
29519000 | USD | |
us-gaap |
Payments To Acquire Available For Sale Securities Debt
PaymentsToAcquireAvailableForSaleSecuritiesDebt
|
29700000 | USD | |
us-gaap |
Payments To Acquire Equity Method Investments
PaymentsToAcquireEquityMethodInvestments
|
0 | USD | |
us-gaap |
Payments To Acquire Equity Method Investments
PaymentsToAcquireEquityMethodInvestments
|
15000000 | USD | |
us-gaap |
Payments To Acquire Intangible Assets
PaymentsToAcquireIntangibleAssets
|
6278000 | USD | |
us-gaap |
Payments To Acquire Intangible Assets
PaymentsToAcquireIntangibleAssets
|
11389000 | USD | |
us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
1056000 | USD | |
us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
601000 | USD | |
CY2017Q4 | us-gaap |
Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
|
0.001 | |
CY2018Q2 | us-gaap |
Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
|
0.001 | |
CY2017Q4 | us-gaap |
Preferred Stock Shares Authorized
PreferredStockSharesAuthorized
|
20000000 | shares |
CY2018Q2 | us-gaap |
Preferred Stock Shares Authorized
PreferredStockSharesAuthorized
|
20000000 | shares |
CY2017Q4 | us-gaap |
Preferred Stock Shares Issued
PreferredStockSharesIssued
|
0 | shares |
CY2018Q2 | us-gaap |
Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
|
2906000 | USD |
CY2017Q4 | us-gaap |
Prepaid Taxes
PrepaidTaxes
|
2842000 | USD |
CY2018Q2 | us-gaap |
Prepaid Taxes
PrepaidTaxes
|
2613000 | USD |
us-gaap |
Proceeds From Issuance Of Warrants
ProceedsFromIssuanceOfWarrants
|
0 | USD | |
us-gaap |
Proceeds From Issuance Of Warrants
ProceedsFromIssuanceOfWarrants
|
2140000 | USD | |
us-gaap |
Proceeds From Payments For Other Financing Activities
ProceedsFromPaymentsForOtherFinancingActivities
|
0 | USD | |
us-gaap |
Proceeds From Payments For Other Financing Activities
ProceedsFromPaymentsForOtherFinancingActivities
|
800000 | USD | |
us-gaap |
Proceeds From Sale Of Available For Sale Securities
ProceedsFromSaleOfAvailableForSaleSecurities
|
43940000 | USD | |
us-gaap |
Proceeds From Sale Of Available For Sale Securities
ProceedsFromSaleOfAvailableForSaleSecurities
|
63565000 | USD | |
us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
3003000 | USD | |
us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
6890000 | USD | |
CY2018Q2 | us-gaap |
Proceeds From Warrant Exercises
ProceedsFromWarrantExercises
|
1500000 | USD |
us-gaap |
Proceeds From Warrant Exercises
ProceedsFromWarrantExercises
|
2100000 | USD | |
CY2017Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
3230000 | USD |
CY2018Q2 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
3455000 | USD |
us-gaap |
Provision For Doubtful Accounts
ProvisionForDoubtfulAccounts
|
410000 | USD | |
us-gaap |
Provision For Doubtful Accounts
ProvisionForDoubtfulAccounts
|
-13000 | USD | |
us-gaap |
Repayments Of Other Debt
RepaymentsOfOtherDebt
|
500000 | USD | |
us-gaap |
Repayments Of Other Debt
RepaymentsOfOtherDebt
|
500000 | USD | |
us-gaap |
Sales Revenue Goods Net
SalesRevenueGoodsNet
|
72420000 | USD | |
CY2018Q2 | us-gaap |
Sales Revenue Goods Net
SalesRevenueGoodsNet
|
41337000 | USD |
us-gaap |
Sales Revenue Goods Net
SalesRevenueGoodsNet
|
79769000 | USD | |
CY2017Q2 | us-gaap |
Selling General And Administrative Expense
SellingGeneralAndAdministrativeExpense
|
28835000 | USD |
CY2017Q2 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
19482000 | USD |
us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
40342000 | USD | |
CY2018Q2 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
34460000 | USD |
us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
59096000 | USD | |
CY2017Q4 | us-gaap |
Restructuring Reserve
RestructuringReserve
|
3549000 | USD |
CY2018Q2 | us-gaap |
Restructuring Reserve
RestructuringReserve
|
0 | USD |
CY2017Q4 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-177655000 | USD |
CY2018Q2 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-208046000 | USD |
CY2017Q2 | us-gaap |
Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
|
38800000 | USD |
us-gaap |
Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
|
72420000 | USD | |
CY2018Q2 | us-gaap |
Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
|
41337000 | USD |
us-gaap |
Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
|
79769000 | USD | |
CY2017Q2 | us-gaap |
Sales Revenue Goods Net
SalesRevenueGoodsNet
|
38800000 | USD |
us-gaap |
Selling General And Administrative Expense
SellingGeneralAndAdministrativeExpense
|
51950000 | USD | |
CY2018Q2 | us-gaap |
Selling General And Administrative Expense
SellingGeneralAndAdministrativeExpense
|
25100000 | USD |
us-gaap |
Selling General And Administrative Expense
SellingGeneralAndAdministrativeExpense
|
51568000 | USD | |
us-gaap |
Share Based Compensation
ShareBasedCompensation
|
14332000 | USD | |
us-gaap |
Share Based Compensation
ShareBasedCompensation
|
10160000 | USD | |
CY2018Q2 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber
|
4600000 | shares |
CY2018Q2 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice
|
16.40 | |
CY2017Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
293134000 | USD |
CY2018Q2 | us-gaap |
Stockholders Equity
StockholdersEquity
|
287989000 | USD |
us-gaap |
Unrecognized Tax Benefits Income Tax Penalties Expense
UnrecognizedTaxBenefitsIncomeTaxPenaltiesExpense
|
0 | USD | |
CY2017Q2 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
39041145 | shares |
us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
38545982 | shares | |
CY2018Q2 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
40061045 | shares |
us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
39641334 | shares | |
us-gaap |
Nature Of Operations
NatureOfOperations
|
<div style="font-family:Times New Roman;font-size:10pt;"><div style="line-height:120%;padding-bottom:13px;padding-top:12px;font-size:13pt;"><font style="font-family:Arial;font-size:13pt;color:#000000;font-style:normal;font-weight:bold;text-decoration:none;">DESCRIPTION OF BUSINESS</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:16px;font-size:12pt;"><font style="font-family:Arial;font-size:12pt;color:#133f7f;font-style:normal;font-weight:bold;text-decoration:none;">Organization and Description of Business</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:4px;text-align:justify;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">Retrophin, Inc. (“we”, “our”, “us”, “Retrophin” and the “Company”) refers to Retrophin, Inc., a Delaware corporation, as well as our direct and indirect subsidiaries. Retrophin is a biopharmaceutical company headquartered in San Diego, California, focused on identifying, developing and delivering life-changing therapies to people living with rare diseases. We regularly evaluate and, where appropriate, act on opportunities to expand our product pipeline through licenses and acquisitions of products in areas that will serve patients with rare diseases and that we believe offer attractive growth characteristics.</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:12px;font-size:10.5pt;"><font style="font-family:Arial;font-size:10.5pt;color:#424242;font-style:italic;font-weight:bold;text-decoration:none;">The Company is developing the following pipeline products:</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:4px;text-align:left;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">The Company is developing fosmetpantotenate (RE-024), a novel small molecule, as a potential treatment for </font><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">pantothenate kinase-associated neurodegeneration (“PKAN”). PKAN is a genetic neurodegenerative disorder that is typically diagnosed in the first decade of life. Consequences of PKAN include dystonia, dysarthria, rigidity, retinal degeneration, and severe digestive problems. There are currently no viable treatment options for patients with PKAN. Fosmetpantotenate is a phosphopantothenate replacement therapy that aims to restore levels of this key substrate in PKAN patients.</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:4px;text-align:left;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">Sparsentan (RE-021) is an investigational product candidate which acts as both a potent </font><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">angiotensin receptor blocker (“ARB”), as well as a selective endothelin receptor antagonist (“ERA”), with in vitro selectivity toward endothelin receptor type A. The Company secured a license to sparsentan from Ligand Pharmaceuticals, Inc. and Bristol-Myers Squibb Company (who referred to it as DARA). The Company is developing sparsentan as a treatment for:</font></div><table cellpadding="0" cellspacing="0" style="padding-top:12px;padding-bottom:4px;font-family:Times New Roman; font-size:10pt;"><tr><td style="width:48px;" rowspan="1" colspan="1"></td><td rowspan="1" colspan="1"></td></tr><tr><td style="vertical-align:top" rowspan="1" colspan="1"><div style="line-height:120%;font-size:9.5pt;padding-left:24px;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#2c2c2c;font-weight:bold;">▪</font></div></td><td style="vertical-align:top;" rowspan="1" colspan="1"><div style="line-height:120%;text-align:left;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#2c2c2c;font-weight:normal;">Focal segmental glomerulosclerosis ("FSGS")</font><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">, which is a leading cause of end-stage renal disease and nephrotic syndrome (“NS”). There are no U.S. Food and Drug Administration ("FDA") approved pharmacologic treatments for FSGS and off-label resources are limited to ACE/ARBs, steroids, and immunosuppressant agents, which are effective in only a subset of patients.</font></div></td></tr></table><table cellpadding="0" cellspacing="0" style="padding-top:12px;padding-bottom:4px;font-family:Times New Roman; font-size:10pt;"><tr><td style="width:48px;" rowspan="1" colspan="1"></td><td rowspan="1" colspan="1"></td></tr><tr><td style="vertical-align:top" rowspan="1" colspan="1"><div style="line-height:120%;font-size:9.5pt;padding-left:24px;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#2c2c2c;font-weight:bold;">▪</font></div></td><td style="vertical-align:top;" rowspan="1" colspan="1"><div style="line-height:120%;text-align:left;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#2c2c2c;font-weight:normal;">Immunoglobulin A nephropathy ("IgAN")</font><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">, which is characterized by hematuria, proteinuria, and variable rates of progressive renal failure. There is no FDA approved treatment for IgAN.</font></div></td></tr></table><div style="line-height:120%;padding-bottom:8px;padding-top:4px;text-align:left;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">The Company is a party to a joint development agreement with Censa Pharmaceuticals Inc. ("Censa"), a privately held biotechnology company focused on developing therapies for orphan metabolic diseases, to evaluate sepiapterin ("CNSA-001") for the treatment of phenylketonuria ("PKU"). CNSA-001 is an orally bioavailable form of a natural precursor of tetrahydrobiopterin ("BH4") with the potential to provide improved phenylalanine ("Phe") reduction in patients with PKU when compared to BH4.</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:4px;text-align:left;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">PKU is a rare, genetic metabolic condition in which the body cannot breakdown Phe due to a missing or defective phenylalanine hydroxylase ("PAH") enzyme. High Phe levels can lead to developmental and physical growth delay, executive function impairment, seizures, and microcephaly caused by toxic Phe accumulation in the brain.</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:4px;text-align:left;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">The Company is party to a three-way Cooperative Research and Development Agreement ("CRADA") with the National Institutes of Health’s National Center for Advancing Translational Sciences and patient advocacy foundation NGLY1.org to collaborate on research efforts aimed at the identification of potential small molecule therapeutics for N-glycanase deficiency ("NGLY1").</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:4px;text-align:left;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">NGLY1 is an extremely rare genetic disorder believed to be caused by a deficiency in an enzyme called N-glycanase-1, which is encoded by the gene NGLY1. The condition has been characterized by symptoms such as developmental delays, seizures, complex hyperkinetic movement disorders, diminished reflexes and an inability to produce tears. There are no approved therapeutic options for NGLY1 deficiency, and current therapeutic strategies are limited to symptom management.</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:4px;text-align:left;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">Liquid ursodeoxycholic acid ("L-UDCA") is a liquid formulation of ursodeoxycholic acid being developed for the treatment of a rare liver disease called primary biliary cholangitis ("PBC"). The Company obtained the rights to L-UDCA in 2016 with the intention of making L-UDCA commercially available to the subset of PBC patients who have difficulty swallowing.</font></div><div style="line-height:120%;padding-bottom:8px;padding-top:12px;font-size:10.5pt;"><font style="font-family:Arial;font-size:10.5pt;color:#424242;font-style:italic;font-weight:bold;text-decoration:none;">The Company sells the following </font><font style="font-family:Arial;font-size:10.5pt;color:#424242;font-style:italic;font-weight:bold;text-decoration:none;">three</font><font style="font-family:Arial;font-size:10.5pt;color:#424242;font-style:italic;font-weight:bold;text-decoration:none;"> products:</font></div><table cellpadding="0" cellspacing="0" style="padding-top:4px;padding-bottom:8px;font-family:Times New Roman; font-size:10pt;"><tr><td style="width:48px;" rowspan="1" colspan="1"></td><td rowspan="1" colspan="1"></td></tr><tr><td style="vertical-align:top" rowspan="1" colspan="1"><div style="line-height:120%;font-size:9.5pt;padding-left:24px;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">•</font></div></td><td style="vertical-align:top;" rowspan="1" colspan="1"><div style="line-height:120%;text-align:justify;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">Chenodal® (chenodiol tablets) is approved in the United States for the treatment of patients suffering from gallstones in whom surgery poses an unacceptable health risk due to disease or advanced age. Chenodal has also been the standard of care for cerebrotendinous xanthomatosis ("CTX") patients for more than three decades and the Company is currently pursuing adding this indication to the label.</font></div></td></tr></table><table cellpadding="0" cellspacing="0" style="padding-top:4px;padding-bottom:8px;font-family:Times New Roman; font-size:10pt;"><tr><td style="width:48px;" rowspan="1" colspan="1"></td><td rowspan="1" colspan="1"></td></tr><tr><td style="vertical-align:top" rowspan="1" colspan="1"><div style="line-height:120%;font-size:9.5pt;padding-left:24px;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">•</font></div></td><td style="vertical-align:top;" rowspan="1" colspan="1"><div style="line-height:120%;text-align:justify;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">Cholbam® (cholic acid capsules) is approved in the United States (approved and marketed in Europe for select indications as Kolbam) for the treatment of bile acid synthesis disorders due to single enzyme defects and is further indicated for adjunctive treatment of patients with peroxisomal disorders.</font></div></td></tr></table><table cellpadding="0" cellspacing="0" style="padding-top:4px;padding-bottom:8px;font-family:Times New Roman; font-size:10pt;"><tr><td style="width:48px;" rowspan="1" colspan="1"></td><td rowspan="1" colspan="1"></td></tr><tr><td style="vertical-align:top" rowspan="1" colspan="1"><div style="line-height:120%;font-size:9.5pt;padding-left:24px;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">•</font></div></td><td style="vertical-align:top;" rowspan="1" colspan="1"><div style="line-height:120%;text-align:justify;font-size:9.5pt;"><font style="font-family:Arial Narrow;font-size:9.5pt;color:#000000;">Thiola® (tiopronin tablets) is approved in the United States for the prevention of cystine (kidney) stone formation in patients with severe homozygous cystinuria.</font></div></td></tr></table></div> |