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TherapeuticsMD Inc

therapeuticsmd.com

TherapeuticsMD (NASDAQ: TXMD) is a pharmaceutical company that licenses its women's health drug portfolio to third parties in exchange for royalties and milestone payments. Revenue comes from a licensing agreement with Mayne Pharma, under which TherapeuticsMD receives royalties on net sales of its products in the United States at a rate of 8.0% on the first $80.0 million in annual net sales and 7.5% on annual net sales above $80.0 million, plus minimum annual royalties of $3.0 million per year for 12 years, adjusted for inflation at 3% annually, per the Mayne License Agreement effective December 30, 2022. One-time milestone payments of $5.0 million, $10.0 million, and $15.0 million are triggered if aggregate U.S. net sales of licensed products reach $100.0 million, $200.0 million, and $300.0 million in a calendar year, respectively. The royalty rate steps down to 2.0% per product upon patent expiration or generic entry. TherapeuticsMD retains IP ownership while Mayne Pharma handles commercialization, with the 20-year royalty term running from the closing date of the transaction.

Products & Services

IMVEXXY (estradiol vaginal inserts, 4 mcg and 10 mcg doses), a women's health product licensed to Mayne Pharma. Patents on IMVEXXY expire in 2032 or 2033. As of December 31, 2025, patent infringement litigation against Sun Pharma related to an ANDA for a generic version of IMVEXXY was ongoing.

Revenue Model

Royalty income from Mayne Pharma on U.S. net sales of licensed products: 8.0% on the first $80.0 million in annual net sales and 7.5% above $80.0 million, with minimum annual royalties of $3.0 million per year for 12 years (inflation-adjusted at 3% annually). Additional one-time milestone payments up to $30.0 million tied to cumulative annual net sales thresholds. Royalty term is 20 years from the December 30, 2022 closing date, per the Mayne License Agreement (10-K, filed 2026-03-30).

Customers & Markets

Mayne Pharma is the sole disclosed licensee and primary revenue counterparty. End market is U.S. women's health, specifically products addressing conditions treated by IMVEXXY. Customer concentration is effectively 100% in Mayne Pharma under the current licensing structure.

Geographic Exposure

United States only, based on the Mayne License Agreement covering U.S. net sales (10-K, filed 2026-03-30).

Financial Snapshot

Revenue
TTM
$3.353M
Gross Margin
Last 4 Quarters
N/A
Net Income
TTM
$179.0K
Current Assets
2026 Q1
Current Liabilities
2026 Q1
Current Ratio
2026 Q1
310.79%
Total Assets
2026 Q1
Total Liabilities
2026 Q1
Book Value
2026 Q1
$26.97M
Cash
2026 Q1
P/E
TTM
129.3
Free Cash Flow
Last 4 Quarters
N/A

Stock Price

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Market Cap: $23.149 Million

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