| Insider Name | Current Shares | Net Change (1yr) | Buy/Sell Ratio |
|---|---|---|---|
| Rajeev M. Shah | 8,297,265 | 0 | - |
| Ventures VI, L.P. 5AM | 4,833,959 | 0 | - |
| Andrew J. Schwab | 4,595,089 | 0 | - |
| Jean-Paul Kress | 4,164,831 | +83,296,638 | ∞ |
| Capital Healthcare Fund LP RA | 2,402,095 | +1,606,823 | 1.42 |
| Sandesh Mahatme | 1,388,274 | +14,576,887 | ∞ |
| Reid Hoffman | 1,166,909 | -6,490,281 | - |
| ROBERT ANG | 911,318 | 0 | - |
| Venture Investments, LLC Alexandria | 282,804 | 0 | - |
| Qing Che Zuraw | 218,652 | +937,080 | ∞ |
| Tirtha Chakraborty | 217,416 | 0 | - |
| Nathan D. Jorgensen | 189,403 | 0 | - |
| Eyal C. Attar | 126,625 | 0 | - |
| Christopher Slapak | 116,000 | 0 | - |
| Alexander Cumbo | 60,000 | +60,000 | ∞ |
| Sarah Burgess Reed | 60,000 | +60,000 | ∞ |
| Michel Detheux | 60,000 | +60,000 | ∞ |
| Han Wook Choi | 51,280 | 0 | - |
| Amy Quinlan | 50,312 | 0 | - |
| Matthew R Patterson | 30,000 | 0 | - |
| Erez Kalir | 30,000 | 0 | - |
| David Charles Lubner | 30,000 | 0 | - |
| Joshua Resnick | 30,000 | 0 | - |
| Daniella Beckman | 30,000 | 0 | - |
| Fouad Namouni | 30,000 | 0 | - |
| Sven Ante Lundberg | 30,000 | 0 | - |
| KUSH PARMAR | 16,911 | 0 | - |
| Wouter Joustra | 3,000 | +3,000 | ∞ |
| Andrew David Levin | 3,000 | +3,000 | ∞ |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Capital Healthcare Fund LP RA | Apr 24 |
Open Market Sale (S)
Market Sale
|
2,402,095 | -165,150 | $15.77 | -$2,604,415 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Capital Healthcare Fund LP RA | Apr 21 |
Open Market Sale (S)
Market Sale
|
2,567,245 | -171,963 | $15.77 | -$2,711,856 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Capital Healthcare Fund LP RA | Apr 21 |
Open Market Sale (S)
Market Sale
|
2,739,208 | -458,411 | $16.28 | -$7,462,931 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Capital Healthcare Fund LP RA | Apr 15 |
Open Market Sale (S)
Market Sale
|
3,197,619 | -53,644 | $16.01 | -$858,840 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Capital Healthcare Fund LP RA | Apr 15 |
Open Market Sale (S)
Market Sale
|
3,251,263 | -153,735 | $15.97 | -$2,455,147 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Capital Healthcare Fund LP RA | Apr 15 |
Open Market Sale (S)
Market Sale
|
3,404,998 | -530,610 | $16.15 | -$8,569,351 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Capital Healthcare Fund LP RA | Apr 10 |
Open Market Sale (S)
Market Sale
|
3,935,608 | -828 | $15.75 | -$13,041 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Capital Healthcare Fund LP RA | Apr 10 |
Open Market Sale (S)
Market Sale
|
3,936,436 | -135,201 | $16.59 | -$2,242,984 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Capital Healthcare Fund LP RA | Apr 10 |
Open Market Sale (S)
Market Sale
|
4,202,499 | -353,242 | $16.32 | -$5,764,909 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Capital Healthcare Fund LP RA | Apr 06 |
Open Market Sale (S)
Market Sale
|
4,607,244 | -537,754 | $16.51 | -$8,878,318 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Capital Healthcare Fund LP RA | Apr 06 |
Open Market Sale (S)
Market Sale
|
5,146,523 | -258,475 | $18.23 | -$4,711,999 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Wouter Joustra | Dec 19 |
Grant/Award Acquisition (A)
Compensation/Award
|
3,000 | +3,000 | $0.00 | +$0 |
| Andrew David Levin | Dec 19 |
Grant/Award Acquisition (A)
Compensation/Award
|
3,000 | +3,000 | $0.00 | +$0 |
| Capital Healthcare Fund LP RA | Dec 19 |
Grant/Award Acquisition (A)
Compensation/Award
|
5,404,998 | -4,625,346 | $10.81 | -$49,999,990 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Qing Che Zuraw | Dec 09 |
Grant/Award Acquisition (A)
Compensation/Award
|
218,652 | +218,652 | $0.00 | +$0 |
| Qing Che Zuraw | Dec 09 |
Disposition to Issuer (D)
Payment to Issuer
|
0 | -218,652 | $0.00 | -$0 |
| Jean-Paul Kress | Dec 09 |
Grant/Award Acquisition (A)
Compensation/Award
|
4,164,831 | +4,164,831 | $0.00 | +$0 |
| Jean-Paul Kress | Dec 09 |
Disposition to Issuer (D)
Payment to Issuer
|
0 | -4,164,831 | $0.00 | -$0 |
| Sandesh Mahatme | Dec 09 |
Grant/Award Acquisition (A)
Compensation/Award
|
1,388,274 | +1,388,274 | $0.00 | +$0 |
| Sandesh Mahatme | Dec 09 |
Disposition to Issuer (D)
Payment to Issuer
|
0 | -694,137 | $0.00 | -$0 |
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