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Ownership

Who owns Zymeworks Inc., from the filings themselves: stakes over 5% (Schedule 13D/G), the institutional managers reporting the stock each quarter (13F), and the funds holding it (N-PORT).

Stakes over 5%

Investors crossing 5% ownership must disclose it. Schedule 13G filers certify the stake is passive; Schedule 13D is the general form for everyone else — founders, strategic holders, and activists alike. Each entry is the holder's most recent disclosure. Coverage begins with SEC's structured filings from December 18, 2024; a holder appears once they file or amend after that date.

Rubric Capital Management LP, David Rosen May 15, 2026

Rubric Capital Management LP: 9.5% · 7,000,000 shares — David Rosen: 9.5% · 7,000,000 shares

Perceptive Advisors LLC, Joseph Edelman, Perceptive Life Sciences Master Fund, Ltd. April 15, 2026

Perceptive Advisors LLC: 5.4% · 3,974,579 shares — Joseph Edelman: 5.4% · 3,974,579 shares — Perceptive Life Sciences Master Fund, Ltd.: 5.4% · 3,974,579 shares

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Super investors holding ZYME

Every institutional manager whose latest 13F reports this stock, largest position first. "% of their portfolio" is the weight inside that manager's own book — how much conviction the position represents; "% of company" is how much of Zymeworks Inc. they hold. Together these 269 managers report 109.25% of shares outstanding.

Investor Position value Shares % of their portfolio % of company As of
EcoR1 Capital, LLC $600M 22,970,388 29.19% 32.37% June 30, 2026
Rubric Capital Management LP $183M 7,000,000 1.68% 9.86% June 30, 2026

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Funds holding ZYME

Funds disclosing this stock in their monthly N-PORT portfolio, with the position's share of the fund's net assets. Together these 201 funds hold 15.62% of shares outstanding — counted inside the manager totals above, not on top of them, since a fund's shares also appear in its manager's 13F.

Fund Position value % of net assets % of company As of
VANGUARD TOTAL STOCK MARKET INDEX FUND $39.4M 0.00% 2.13% June 30, 2026
iShares Russell 2000 ETF $30.5M 0.04% 1.72% March 31, 2026

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