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$ZYME
$28.37 +$0.15 (0.53%) Close

Ownership

13F as of Q2 2026 · 71.0M shares outstanding

Who owns ZYME?

By type of holder
Institutions 96.2% Insiders 3.8% Everyone else 0.0%
Concentration Top 10 holders own 129.9%
Oleg Nodelman 32.4% · EcoR1 Capital, LLC 32.4%
Institutional ownership
96.2%
-2.8 pts vs last qtr
Institutional holders
200
-12 vs last qtr
Net shares bought
−2.0M
by institutions in Q2 2026
New / sold out
23 / 35
positions opened vs closed

How is ownership changing?

Institutions, last 8 quarters

Biggest buyers in Q2 2026
  • Nomura Asset Management International Inc. NEW +889.8K
  • Perceptive Advisors LLC +672.9K

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Biggest sellers in Q2 2026
  • MPM Bioimpact LLC SOLD OUT −565.2K
  • Nuveen, LLC −532.3K

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Who is planning to sell?

Notices of proposed sale, last 12 months
$20.5M
15 notices from 10 people
Shares covered
839.1K
1.18% of the company
Arranged in advance
0%
of the value is under a 10b5-1 plan
Under a 10b5-1 plan No plan
$0$3.1M$6.1MNov 2025: $5.3M without a planNovDec 2025: $1.3M without a planDecJan 2026: $3.7M without a planJanFeb 2026: $3.7M without a planFebMar 2026: $6.1M without a planMarAprMayJunJulAugSepOct 2026: $349.4K without a planOct
Largest proposed sellers
  • Jeffrey T L Smith Former officer $6.35M
  • Leone D Patterson Former officer $3.85M

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Every notice on Red Flags →

A Form 144 is notice of a planned sale, not the sale itself. What insiders actually sold is on Insider Transactions.

Is your stake being diluted?

Diluted share count, FY2020–FY2025
+49.7%
+8.40% a year
Each share's claim on the business
−33.2%
shrank without buying or selling a share
Spent on buybacks vs paid in stock
$71.7M vs $97.8M
over 6 fiscal years
Diluted shares, split-adjusted
48.9M62.8M76.6M2020: 50.4M shares'202021: 52.1M shares'212022: 65.2M shares'222023: 68.9M shares'232024: 75.9M shares'242025: 75.4M shares'25
Buybacks Stock-based comp
$0$20.8M$41.7M2020 buybacks: $02020 stock comp: $29.1M'202021 buybacks: $02021 stock comp: $10.8M'212022 buybacks: $02022 stock comp: $4.0M'222023 buybacks: $02023 stock comp: $8.1M'232024 buybacks: $30.1M2024 stock comp: $17.8M'242025 buybacks: $41.7M2025 stock comp: $28.0M'25

How patient are the owners?

Institutional shares by how long they've been held
5+ years0% 3–5 years82% 1–3 years9% Under 1 year9%
Quarterly turnover
7.3%
of institutional shares changed hands
Top 10 managers, median time held
3.5 years

Super Investors

Investment managers reporting ZYME on Form 13F
EC
EcoR1 Capital, LLC
13D · 30.7%
Shares
23.0M
% of company
32.37%
Change vs last qtr
Unchanged
Held since
2022
RC
Rubric Capital Management LP
Shares
7.0M
% of company
9.86%
Change vs last qtr
Unchanged
Held since
2022

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Institutional Funds

Mutual funds and ETFs reporting ZYME on Form N-PORT; together they hold 15.1% of the company
VT
Position value
$39.4M
% of company
2.13%
% of the fund
0.00%
As of
June 30, 2026
IR
iShares Trust
Position value
$31.6M
% of company
1.70%
% of the fund
0.04%
As of
June 30, 2026

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Insiders and 5%+ holders

From Forms 3/4/5 and Schedules 13D/G
ON
Oleg Nodelman
5%+ holder13D · 30.7%
Shares
23.0M
% of company
32.37%
Change vs last qtr
—
Held since
—
EC
EcoR1 Capital Fund Qualified, L.P.
5%+ holder13D · 28.8%
Shares
21.6M
% of company
30.42%
Change vs last qtr
—
Held since
—

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