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Super Investors Blue Water Life Science Advisors, LP
BW

Blue Water Life Science Advisors, LP

Quarterly 13F snapshot: US-listed longs only, no performance figures — 13F data cannot support them.

Portfolio value
$159M
Positions
9
Quarter ended
June 30, 2026
Filed
August 14, 2026

Reported portfolio value by quarter (23 quarters reported)

$336M $101M
Q4 20 Q1 22 Q2 23 Q3 24 Q4 25 Q2 26

$336M in Q4 2020 → $159M now. Hover for any quarter.

Holdings

As reported for the quarter ended June 30, 2026. Activity is the change in share count since the prior quarter's filing.

Holding % of portfolio Activity Shares Value
Caredx Inc 21.4% Added 27% 1,190,000 $33.9M
10x Genomics Inc 15.5% Trimmed 41% 642,000 $24.6M
Personalis Inc 14.1% Unchanged 1,676,300 $22.5M
AB Adaptive Biotechnologies Cor 13.6% Unchanged 1,010,145 $21.7M
Guardant Health Inc 10.8% Trimmed 53% 114,747 $17.2M
Quanterix Corp 9.5% Added 62% 3,474,202 $15M
Natera Inc 5.9% Trimmed 23% 34,494 $9.36M
Billiontoone Inc 5.3% Added 250% 70,000 $8.4M
Tempus Ai Inc 3.8% Trimmed 33% 105,412 $6.11M

Timeline of changes

What changed each quarter, from the filings' own share counts. Largest moves first; most recent 8 quarters.

Q2 2026

quarter ended June 30, 2026 · filed August 14, 2026

Company Action Shares changed Value of change % of portfolio
Guardant Health Inc Trimmed −127,500 −$19.1M 10.8%
10x Genomics Inc Trimmed −448,000 −$17.2M 15.5%
Twist Bioscience Corp Exited −276,000 −$13.1M —
Caredx Inc Added +255,000 +$7.27M 21.4%
Billiontoone Inc Added +50,000 +$6M 5.3%
Quanterix Corp Added +1,332,055 +$5.75M 9.5%
Tempus Ai Inc Trimmed −51,000 −$2.95M 3.8%
Natera Inc Trimmed −10,300 −$2.8M 5.9%

Q1 2026

quarter ended March 31, 2026 · filed May 14, 2026

Company Action Shares changed Value of change % of portfolio
10x Genomics Inc New +1,090,000 +$23.1M 18.6%
Natera Inc Trimmed −96,700 −$19.3M 7.2%
AB Adaptive Biotechnologies Cor Trimmed −755,000 −$10.5M 11.2%
Guardant Health Inc Trimmed −112,800 −$10.4M 17.9%
Grail Inc Exited −99,000 −$8.47M —
Caredx Inc Added +425,000 +$7.38M 13.0%
Twist Bioscience Corp Trimmed −107,000 −$5.08M 10.5%
Tempus Ai Inc Added +70,000 +$3.17M 5.7%
Billiontoone Inc New +20,000 +$1.58M 1.3%
Quanterix Corp Added +50,000 +$176K 6.0%

Q4 2025

quarter ended December 31, 2025 · filed February 17, 2026

Company Action Shares changed Value of change % of portfolio
Twist Bioscience Corp New +383,000 +$12.1M 7.6%
Grail Inc New +99,000 +$8.47M 5.3%
Quanterix Corp Added +1,134,400 +$7.21M 8.4%
AB Adaptive Biotechnologies Cor Trimmed −380,000 −$6.17M 18.0%
Guardant Health Inc Trimmed −50,600 −$5.17M 22.8%
Tempus Ai Inc Added +14,000 +$827K 3.2%

Q3 2025

quarter ended September 30, 2025 · filed November 14, 2025

Company Action Shares changed Value of change % of portfolio
1G 10x Genomics Inc-class A Exited −1,100,720 −$12.7M —
Akoya Biosciences Inc Exited −4,697,785 −$6.11M —
Tempus Ai Inc New +72,412 +$5.84M 5.3%
Natera Inc Trimmed −25,000 −$4.02M 20.8%
Caredx Inc Trimmed −214,014 −$3.11M 6.8%
Guardant Health Inc Trimmed −33,400 −$2.09M 23.1%

Q2 2025

quarter ended June 30, 2025 · filed August 14, 2025

Company Action Shares changed Value of change % of portfolio
Guardant Health Inc Trimmed −255,000 −$13.3M 18.1%
1G 10x Genomics Inc-class A New +1,100,720 +$12.7M 10.1%
Natera Inc Trimmed −42,000 −$7.1M 22.3%
Quanterix Corp Added +585,572 +$3.89M 5.0%
Personalis Inc Added +500,900 +$3.29M 8.7%

Q1 2025

quarter ended March 31, 2025 · filed May 15, 2025

Company Action Shares changed Value of change % of portfolio
Natera Inc Trimmed −46,300 −$6.55M 29.2%
Exact Sciences Corp Exited −78,843 −$4.43M —
Tempus Ai Inc Exited −90,000 −$3.04M —
Caredx Inc Added +120,014 +$2.13M 12.7%
Quanterix Corp Added +293,782 +$1.91M 2.4%
Personalis Inc Added +42,500 +$149K 4.1%

Q4 2024

quarter ended December 31, 2024 · filed February 13, 2025

Company Action Shares changed Value of change % of portfolio
Exact Sciences Corp Trimmed −176,400 −$9.91M 3.9%
Guardant Health Inc Added +243,000 +$7.42M 18.8%
Natera Inc Trimmed −36,300 −$5.75M 35.7%
Tempus Ai Inc New +90,000 +$3.04M 2.7%
Personalis Inc Added +132,900 +$768K 5.8%

Q3 2024

quarter ended September 30, 2024 · filed November 14, 2024

Company Action Shares changed Value of change % of portfolio
Natera Inc Trimmed −212,000 −$26.9M 32.5%
Exact Sciences Corp Added +197,900 +$13.5M 15.3%
AB Adaptive Biotechnologies Cor New +2,145,145 +$11M 9.7%
Personalis Inc New +1,000,000 +$5.38M 4.7%
10x Genomics Inc Exited −230,000 −$4.47M —
Caredx Inc Added +94,000 +$2.94M 16.6%
Guardant Health Inc Trimmed −120,000 −$2.75M 9.1%
Quanterix Corp Trimmed −200,000 −$2.59M 0.9%
Maxcyte Inc Exited −603,937 −$2.37M —

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