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Super Investors MPM ASSET MANAGEMENT LLC
MA

MPM ASSET MANAGEMENT LLC

Quarterly 13F snapshot: US-listed longs only, no performance figures — 13F data cannot support them.

Portfolio value
$44.5M
Positions
4
Quarter ended
September 30, 2025
Filed
November 14, 2025

Reported portfolio value by quarter (50 quarters reported)

$707M $43.3M
Q2 13 Q4 15 Q2 18 Q4 20 Q2 23 Q3 25

$226M in Q2 2013 → $44.5M now. Hover for any quarter.

Holdings

As reported for the quarter ended September 30, 2025. Activity is the change in share count since the prior quarter's filing.

Holding % of portfolio Activity Shares Value
Entrada Therapeutics, Inc. 57.1% Unchanged 4,381,062 $25.4M
Dyne Therapeutics, Inc. 19.4% Unchanged 682,376 $8.63M
Werewolf Therapeutics, Inc. 19.1% Unchanged 4,309,860 $8.49M
Repare Therapeutics, Inc. 4.4% Unchanged 1,121,318 $1.97M

Timeline of changes

What changed each quarter, from the filings' own share counts. Largest moves first; most recent 8 quarters.

Q3 2025

quarter ended September 30, 2025 · filed November 14, 2025

Company Action Shares changed Value of change % of portfolio
Adaptimmune Therapeutics PLC Exited −4,809,677 −$1.15M —

Q2 2025

quarter ended June 30, 2025 · filed August 14, 2025

Company Action Shares changed Value of change % of portfolio
Iteos Therapeutics, Inc. Exited −2,738,785 −$16.4M —
Adaptimmune Therapeutics PLC Trimmed −526,038 −$126K 2.7%

Q1 2025

quarter ended March 31, 2025 · filed May 15, 2025

Company Action Shares changed Value of change % of portfolio
Repare Therapeutics, Inc. Trimmed −562,389 −$555K 1.6%
Adaptimmune Therapeutics PLC Trimmed −219,746 −$43.3K 1.5%
Werewolf Therapeutics, Inc. Added +25,688 +$25K 6.0%

Q4 2024

quarter ended December 31, 2024 · filed February 14, 2025

Company Action Shares changed Value of change % of portfolio
Entrada Therapeutics, Inc. Trimmed −44,722 −$773K 60.9%
Repare Therapeutics, Inc. Trimmed −558,929 −$732K 1.8%

Q3 2024

quarter ended September 30, 2024 · filed November 13, 2024

Company Action Shares changed Value of change % of portfolio
Dyne Therapeutics, Inc. Trimmed −879,120 −$31.6M 16.9%

Q2 2024

quarter ended June 30, 2024 · filed August 14, 2024

Company Action Shares changed Value of change % of portfolio
Dyne Therapeutics, Inc. Trimmed −1,889,807 −$66.7M 30.3%

Q1 2024

quarter ended March 31, 2024 · filed May 15, 2024

Company Action Shares changed Value of change % of portfolio
Dyne Therapeutics, Inc. Trimmed −1,500,000 −$42.6M 40.0%
Harpoon Therapeutics, Inc. Exited −313,136 −$3.56M —

Q4 2023

quarter ended December 31, 2023 · filed February 13, 2024

Company Action Shares changed Value of change % of portfolio
Harpoon Therapeutics, Inc. New +313,136 +$3.56M 1.7%
Harpoon Therapeutics, Inc. Exited −313,136 −$1.26M —
Adaptimmune Therapeutics PLC Trimmed −731,640 −$580K 2.2%

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