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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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FY2020
12 months to Dec 31, 2020
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Change in fair value of contingent consideration | |||||
| Depreciation and amortization | |||||
| Stock-based compensation expense | |||||
| Noncash research and development expense (finance lease) | |||||
| Noncash operating lease expense | |||||
| Loss on fixed assets disposal | |||||
| Unrealized loss (gain) on equity securities | |||||
| Excess inventory reserve | |||||
| Non-cash interest expense | |||||
| Other non-cash items | |||||
| Gain on foreign currency exchange rates | |||||
| Proceeds from sale of accounts receivable | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Prepaid expenses and other assets | |||||
| Transfer of invoices to Factor | |||||
| Inventory | |||||
| Operating lease right-of-use assets | |||||
| Accounts payable | |||||
| Operating lease liabilities | |||||
| Collaboration research advancement | |||||
| Accrued expenses and other liabilities | |||||
| Accrued interest payable under finance lease | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities: | |||||
| Purchase of property, plant and equipment | |||||
| Proceeds from previously transferred invoices | |||||
| Purchases of marketable securities | |||||
| Proceeds from maturities of marketable securities | |||||
| Proceeds from sales of marketable securities | |||||
| Proceeds from sale of Durham, North Carolina manufacturing facility | |||||
| Purchase of intangible assets | |||||
| Proceeds from sale of priority review voucher | |||||
| Net cash provided by investing activities | |||||
| Cash flows from financing activities: | |||||
| Net cash transferred to 2seventy bio at separation | |||||
| Proceeds from the issuance of debt, net of fees paid to lender | |||||
| Proceeds allocated to detachable warrants issued in conjunction with debt | |||||
| Payments of debt issuance costs | |||||
| Proceeds from public offering of common stock, net of issuance costs | |||||
| Public Offering | |||||
| Private Placement | |||||
| Total proceeds from public offering of common stock, net of issuance costs | |||||
| Proceeds from exercise of stock options and ESPP contributions | |||||
| Proceeds from the transfer of invoices | |||||
| Principal payments on finance leases | |||||
| Other financing activities | |||||
| Net cash provided by financing activities | |||||
| Increase (decrease) in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash at beginning of year | |||||
| Cash, cash equivalents and restricted cash at end of year | |||||
| Supplemental cash flow disclosures: | |||||
| Reduction of right of use asset and associated lease liability due to lease reassessment | |||||
| Issuance of unrestricted stock awards to settle accrued employee compensation | |||||
| Cash paid during the period for income taxes | |||||
| Right-of-use assets obtained in exchange for operating lease liabilities | |||||
| Purchases of property, plant and equipment included in accounts payable and accrued expenses | |||||
| Purchases of intangible assets included in accrued expenses | |||||
| Right-of-use assets obtained in exchange for finance lease liabilities | |||||
| Offering expenses included in accounts payable and accrued expenses | |||||
| Beneficiary interest obtained in transferred invoices | |||||
| Cash paid (refunded) during the period for income taxes | |||||
| Reconciliation of cash, cash equivalents and restricted cash: | |||||
| Cash and cash equivalents | |||||
| Restricted cash included in receivables and other current assets | |||||
| Restricted cash included in restricted cash and other non-current assets | |||||
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