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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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FY2020
12 months to Dec 31, 2020
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FY2019
12 months to Dec 31, 2019
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FY2018
12 months to Dec 31, 2018
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Goodwill and IPR&D impairment | |||||
| Impairments and losses on disposals of long-lived assets | |||||
| Gain on sale of RUO kit assets | |||||
| Depreciation and amortization | |||||
| Stock-based compensation | |||||
| Amortization of debt discount and issuance costs | |||||
| Impairment losses | |||||
| Income tax benefit | |||||
| Remeasurements of liabilities associated with business combinations | |||||
| Benefit from income taxes | |||||
| Debt extinguishment costs | |||||
| Post-combination expense for acceleration of unvested equity and deferred stock compensation | |||||
| Amortization of premiums and discounts on investment securities | |||||
| Non-cash lease expense | |||||
| Other | |||||
| Changes in operating assets and liabilities, net of businesses acquired: | |||||
| Accounts receivable | |||||
| Inventory | |||||
| Prepaid expenses and other current assets | |||||
| Other assets | |||||
| Accounts payable | |||||
| Accrued expenses and other long-term liabilities | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities: | |||||
| Purchases of marketable securities | |||||
| Proceeds from sales of marketable securities | |||||
| Proceeds from maturities of marketable securities | |||||
| Acquisition of businesses, net of cash acquired | |||||
| Proceeds from sale of RUO kit assets | |||||
| Purchases of property and equipment | |||||
| Other | |||||
| Net cash used in investing activities | |||||
| Cash flows from financing activities: | |||||
| Proceeds from public offerings of common stock, net | |||||
| Proceeds from issuance of common stock | |||||
| Proceeds from issuance of convertible senior notes, net | |||||
| Proceeds from issuance of debt, net | |||||
| Payments of debt extinguishment costs | |||||
| Loan payments | |||||
| Finance lease principal payments | |||||
| Settlement of acquisition obligations | |||||
| Net cash provided by financing activities | |||||
| Net (decrease) increase in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash at beginning of period | |||||
| Cash, cash equivalents and restricted cash at end of period | |||||
| Supplemental cash flow information: | |||||
| Interest paid | |||||
| Supplemental cash flow information of non-cash investing and financing activities: | |||||
| Consideration receivable for sale of RUO kit assets | |||||
| Equipment acquired through finance leases | |||||
| Purchases of property and equipment in accounts payable and accrued liabilities | |||||
| Warrants issued pursuant to debt agreement | |||||
| Common stock issued for acquisition of businesses | |||||
| Consideration payable for acquisition of businesses | |||||
| Operating lease assets obtained in exchange for lease obligations, net | |||||
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