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Generation Bio Co.

generationbio.com

What Do They Do?

Develops treatments for people with autoimmune diseases by using targeted nanoparticles to silence disease-driving genes in T cells, a type of immune cell.

How Do They Make Money?

Moderna reimburses Generation Bio for research costs; the company may also receive upfront fees, milestone payments when specified events occur, and royalties on sales of licensed products.

FY2024 revenue

Who Are Their Customers?

Moderna is the collaboration partner, reimbursing research costs and holding options to license specified products; the agreement covers preclinical research programs.

Do Revenues Turn Into Profits?

No. It lost $131.7M in FY2024.

Operating income, FY2024
−716% of revenue
▲ +3% (Loss) vs FY2023 (−$138.6M, −2347%)
Net income, FY2024
−662% of revenue
▲ +4% (Loss) vs FY2023 (−$126.6M, −2145%)
Free cash flow, FY2024
−457% of revenue
▲ +51% (Loss) vs FY2023 (−$60.1M, −1019%)

How Are They Changing?

Since the FY2024 annual report
Latest quarter: Q3 FY2025, the three months to Sep 30, 2025
Revenue
▼ −79%
vs $7.6M in Q3 FY2024
Net income
▼ −64% (Loss)
vs −$15.3M in Q3 FY2024
  • Feb 9, 2026 XOMA completed its acquisition of Generation Bio The offer provided $4.2913 per share in cash plus one contingent value right.
  • Dec 15, 2025 Generation Bio agreed to be acquired by XOMA The proposed offer combined cash per share with one contingent value right.
  • Oct 22, 2025 McDonough left the CEO role; Howze became interim CEO McDonough continued as board chair after stepping down as CEO.

From broad genetic medicines to autoimmune treatments The older report described a genetic-medicine platform for liver, retina, and other diseases; the latest report focuses on developing siRNA treatments that silence targets in T cells for autoimmune diseases.

Who Do They Compete With?

Competes with argenx, Kymera Therapeutics, Monte Rosa Therapeutics, Nurix Therapeutics, Amgen, AbbVie, Hoffmann La Roche, Alnylam Pharmaceuticals, Arrowhead Pharmaceuticals, Wave Life Sciences, Capstan Therapeutics, Orna Therapeutics, and Moderna

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