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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|
| Cash flows from operating activities: | ||||
| Net loss | ||||
| Adjustments to reconcile net loss to net cash used in operating activities: | ||||
| Change in fair value of contingent consideration | ||||
| Depreciation and amortization | ||||
| Stock-based compensation expense | ||||
| Goodwill impairment charge | ||||
| Gain (loss) on sale of assets | ||||
| Novo | ||||
| Regeneron | ||||
| Other non-cash items | ||||
| Changes in operating assets and liabilities: | ||||
| Prepaid expenses and other assets | ||||
| Operating lease right-of-use assets | ||||
| Accounts payable | ||||
| Accrued expenses and other liabilities | ||||
| Operating lease liabilities | ||||
| Deferred revenue | ||||
| Collaboration research advancement | ||||
| Net cash used in operating activities | ||||
| Cash flows from investing activities: | ||||
| Purchases of property, plant and equipment | ||||
| Proceeds from sale of assets | ||||
| Novo | ||||
| Regeneron | ||||
| Proceeds from sale of equipment | ||||
| Purchases of marketable securities | ||||
| Proceeds from maturities of marketable securities | ||||
| Purchase of intangible assets | ||||
| Purchase of restricted investments | ||||
| Proceeds from maturities of restricted investments | ||||
| Net cash provided by investing activities | ||||
| Cash flows from financing activities: | ||||
| Transfers from bluebird bio | ||||
| Proceeds from issuance of common stock in public offering, net of issuance costs | ||||
| Proceeds from issuance of common stock to Regeneron, net of issuance costs | ||||
| Proceeds from issuance of common stock in private placement, net of issuance costs | ||||
| Proceeds from exercise of stock options and ESPP contributions | ||||
| Net cash provided by financing activities | ||||
| Increase (decrease) in cash, cash equivalents and restricted cash and cash equivalents | ||||
| Cash, cash equivalents and restricted cash and cash equivalents at beginning of year | ||||
| Cash, cash equivalents and restricted cash and cash equivalents at end of year | ||||
| Supplemental cash flow disclosures: | ||||
| Purchases of property, plant and equipment included in accounts payable and accrued expenses | ||||
| Right-of-use assets obtained in exchange for operating lease liabilities | ||||
| Non-cash return of bRT-related assets to bluebird bio | ||||
| Increase of right-of-use asset and associated lease liability due to lease reassessment | ||||
| Issuance of unrestricted stock awards to settle accrued employee compensation | ||||
| Reconciliation of cash, cash equivalents and restricted cash and cash equivalents: | ||||
| Cash and cash equivalents | ||||
| Restricted cash and cash equivalents included in restricted investments and other non-current assets | ||||
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