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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash used in operating activities | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operations: | |||||
| Deferred income taxes | |||||
| Share-based compensation expense | |||||
| Accretion expense of deferred royalty obligation | |||||
| Cumulative catch-up adjustment, deferred royalty obligation | |||||
| Write-downs of inventory | |||||
| Depreciation | |||||
| Amortization of operating lease right-of-use assets | |||||
| Share of results in joint venture | |||||
| Convertible loans, derivatives, decrease in fair value | |||||
| Change in defined benefit pension liabilities | |||||
| Warrant obligations, decrease in fair value | |||||
| Deerfield Warrants | |||||
| Total warrant obligations, decrease in fair value | |||||
| Amortization of debt discount, senior secured term loan | |||||
| Senior Secured Term Loan | |||||
| Convertible Loans | |||||
| Total amortization of debt discount, senior secured term loan | |||||
| Loss on debt extinguishment | |||||
| Impairment of long-lived assets and prepaid expenses and other related costs | |||||
| Other | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable, net | |||||
| Inventory | |||||
| Prepaid expenses and other current assets | |||||
| Other long-term assets | |||||
| Accounts payable | |||||
| Accrued expenses and other current liabilities | |||||
| Operating lease liabilities | |||||
| Other long-term liabilities | |||||
| Net cash used in operating activities | |||||
| Cash flows used in investing activities | |||||
| Payment for purchases of property and equipment | |||||
| Proceeds from the sale of equipment | |||||
| Net cash provided by (used in) investing activities | |||||
| Cash flows provided by financing activities | |||||
| Proceeds from sale of common shares, net of transaction costs | |||||
| Proceeds from deferred royalty transaction, net of transaction costs | |||||
| Proceeds from share issuance under stock purchase plan | |||||
| Proceeds from senior secured term loans | |||||
| Payments of third-party transaction costs related to senior secured term loans | |||||
| Proceeds from equity issuance, net of transaction costs | |||||
| Convertible loans exchange | |||||
| Proceeds from the exercise of options | |||||
| Taxes paid related to net settled equity awards | |||||
| Net cash provided by financing activities | |||||
| Net decrease in cash and cash equivalents | |||||
| Exchange (losses)/gains on cash and cash equivalents | |||||
| Cash and cash equivalents at beginning of year | |||||
| Cash and cash equivalents at end of year | |||||
| Supplemental Cash Flow Information: | |||||
| Interest paid | |||||
| Interest received | |||||
| Payments made under royalty financing transaction | |||||
| Supplemental Non-Cash Investing Activities: | |||||
| Issuance of shares, Deerfield Exchange Agreement | |||||
| Issuance of warrants, Deerfield Exchange Agreement | |||||
| Capital expenditures recorded in Accounts payable and Accrued expenses and other current liabilities | |||||
| Transaction costs recorded in Accounts payable and other current liabilities and Other long-term liabilities | |||||
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