2015 Q1 Form 10-K Financial Statement
#000119312515050223 Filed on February 13, 2015
Income Statement
Concept | 2015 Q1 | 2014 | 2013 Q4 |
---|---|---|---|
Revenue | $18.50M | $50.60M | $10.80M |
YoY Change | 122.89% | 7.2% | 27.06% |
Cost Of Revenue | |||
YoY Change | |||
Gross Profit | |||
YoY Change | |||
Gross Profit Margin | |||
Selling, General & Admin | $12.70M | $44.50M | $8.300M |
YoY Change | 42.7% | 63.6% | -18.63% |
% of Gross Profit | |||
Research & Development | $58.04M | $190.2M | $32.10M |
YoY Change | 32.63% | 68.43% | 47.93% |
% of Gross Profit | |||
Depreciation & Amortization | $3.690M | $11.93M | $2.600M |
YoY Change | 41.92% | 16.59% | 30.0% |
% of Gross Profit | |||
Operating Expenses | $70.76M | $455.5M | $40.44M |
YoY Change | -74.49% | 225.13% | -58.24% |
Operating Profit | -$52.22M | -$405.0M | |
YoY Change | -80.59% | 335.73% | |
Interest Expense | $1.000M | $2.600M | $300.0K |
YoY Change | 233.33% | 136.36% | -142.86% |
% of Operating Profit | |||
Other Income/Expense, Net | $1.014M | $4.376M | $0.00 |
YoY Change | 303.98% | 328.18% | -100.0% |
Pretax Income | -$51.21M | -$400.6M | -$29.30M |
YoY Change | -80.95% | 335.82% | -59.75% |
Income Tax | -$400.0K | -$40.21M | $3.000M |
% Of Pretax Income | |||
Net Earnings | -$50.78M | -$360.4M | -$32.36M |
YoY Change | -79.77% | 303.92% | -47.97% |
Net Earnings / Revenue | -274.47% | -712.24% | -299.6% |
Basic Earnings Per Share | |||
Diluted Earnings Per Share | -$618.8K | -$4.851M | -$515.1K |
COMMON SHARES | |||
Basic Shares Outstanding | 83.76M shares | 63.43M shares | |
Diluted Shares Outstanding |
Balance Sheet
Concept | 2015 Q1 | 2014 | 2013 Q4 |
---|---|---|---|
SHORT-TERM ASSETS | |||
Cash & Short-Term Investments | $967.0M | $696.7M | $245.9M |
YoY Change | 45.3% | 183.33% | 100.2% |
Cash & Equivalents | $306.6M | $75.20M | $53.17M |
Short-Term Investments | $660.4M | $621.5M | $192.7M |
Other Short-Term Assets | $13.20M | $9.700M | $3.900M |
YoY Change | 57.14% | 148.72% | 50.0% |
Inventory | |||
Prepaid Expenses | |||
Receivables | $10.10M | $39.90M | $4.200M |
Other Receivables | $0.00 | $0.00 | $0.00 |
Total Short-Term Assets | $1.090B | $746.4M | $254.0M |
YoY Change | 61.73% | 193.86% | 102.32% |
LONG-TERM ASSETS | |||
Property, Plant & Equipment | $21.17M | $21.70M | $16.45M |
YoY Change | 34.55% | 32.32% | -16.93% |
Goodwill | |||
YoY Change | |||
Intangibles | |||
YoY Change | |||
Long-Term Investments | $483.8M | $279.8M | $150.1M |
YoY Change | 23.89% | 86.41% | 5.56% |
Other Assets | $33.70M | $31.70M | |
YoY Change | |||
Total Long-Term Assets | $538.6M | $333.2M | $166.5M |
YoY Change | 32.58% | 100.12% | 2.8% |
TOTAL ASSETS | |||
Total Short-Term Assets | $1.090B | $746.4M | $254.0M |
Total Long-Term Assets | $538.6M | $333.2M | $166.5M |
Total Assets | $1.629B | $1.080B | $420.5M |
YoY Change | 50.77% | 156.74% | 46.26% |
SHORT-TERM LIABILITIES | |||
YoY Change | |||
Accounts Payable | $15.49M | $15.10M | $5.896M |
YoY Change | 207.44% | 155.93% | 33.39% |
Accrued Expenses | $14.43M | $23.70M | $14.16M |
YoY Change | -13.09% | 66.9% | 22.51% |
Deferred Revenue | |||
YoY Change | |||
Short-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Long-Term Debt Due | |||
YoY Change | |||
Total Short-Term Liabilities | $80.69M | $95.30M | $53.86M |
YoY Change | -3.74% | 76.81% | 11.42% |
LONG-TERM LIABILITIES | |||
Long-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Other Long-Term Liabilities | $51.60M | $48.00M | $96.30M |
YoY Change | 5060.0% | -50.16% | -8.37% |
Total Long-Term Liabilities | $51.60M | $48.00M | $96.30M |
YoY Change | 5060.0% | -50.16% | -8.37% |
TOTAL LIABILITIES | |||
Total Short-Term Liabilities | $80.69M | $95.30M | $53.86M |
Total Long-Term Liabilities | $51.60M | $48.00M | $96.30M |
Total Liabilities | $132.3M | $143.3M | $150.2M |
YoY Change | 5.55% | -4.59% | -2.14% |
SHAREHOLDERS EQUITY | |||
Retained Earnings | -$1.007B | -$596.2M | |
YoY Change | 18.91% | 17.6% | |
Common Stock | $2.452B | $846.9M | |
YoY Change | 37.95% | 35.41% | |
Preferred Stock | |||
YoY Change | |||
Treasury Stock (at cost) | |||
YoY Change | |||
Treasury Stock Shares | |||
Shareholders Equity | $1.497B | $936.3M | $270.3M |
YoY Change | |||
Total Liabilities & Shareholders Equity | $1.629B | $1.080B | $420.5M |
YoY Change | 50.77% | 156.74% | 46.26% |
Cashflow Statement
Concept | 2015 Q1 | 2014 | 2013 Q4 |
---|---|---|---|
OPERATING ACTIVITIES | |||
Net Income | -$50.78M | -$360.4M | -$32.36M |
YoY Change | -79.77% | 303.92% | -47.97% |
Depreciation, Depletion And Amortization | $3.690M | $11.93M | $2.600M |
YoY Change | 41.92% | 16.59% | 30.0% |
Cash From Operating Activities | -$26.30M | -$165.6M | -$22.40M |
YoY Change | -36.93% | 141.2% | -67.49% |
INVESTING ACTIVITIES | |||
Capital Expenditures | $2.110M | $8.961M | -$900.0K |
YoY Change | 443.81% | 123.69% | 50.0% |
Acquisitions | |||
YoY Change | |||
Other Investing Activities | -$339.2M | -$514.9M | $56.90M |
YoY Change | -4.29% | 307.04% | 28.73% |
Cash From Investing Activities | -$341.3M | -$548.8M | $56.10M |
YoY Change | -10.14% | 320.52% | 28.97% |
FINANCING ACTIVITIES | |||
Cash Dividend Paid | |||
YoY Change | |||
Common Stock Issuance & Retirement, Net | $496.4M | ||
YoY Change | |||
Debt Paid & Issued, Net | |||
YoY Change | |||
Cash From Financing Activities | 599.0M | 736.5M | 7.600M |
YoY Change | -16.68% | 266.55% | 660.0% |
NET CHANGE | |||
Cash From Operating Activities | -26.30M | -165.6M | -22.40M |
Cash From Investing Activities | -341.3M | -548.8M | 56.10M |
Cash From Financing Activities | 599.0M | 736.5M | 7.600M |
Net Change In Cash | 231.4M | 22.10M | 41.30M |
YoY Change | -22.19% | 1152.83% | -269.26% |
FREE CASH FLOW | |||
Cash From Operating Activities | -$26.30M | -$165.6M | -$22.40M |
Capital Expenditures | $2.110M | $8.961M | -$900.0K |
Free Cash Flow | -$28.41M | -$174.6M | -$21.50M |
YoY Change | -32.5% | 140.23% | -68.52% |
Facts In Submission
Frame | Concept Type | Concept / XBRL Key | Value | Unit |
---|---|---|---|---|
CY2012Q1 | dei |
Entity Number Of Employees
EntityNumberOfEmployees
|
115 | Employee |
CY2013Q1 | us-gaap |
Shares Issued Price Per Share
SharesIssuedPricePerShare
|
20.13 | |
CY2012Q1 | us-gaap |
Shares Issued Price Per Share
SharesIssuedPricePerShare
|
10.75 | |
CY2005Q3 | us-gaap |
Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1
ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
|
80.00 | |
CY2005Q3 | us-gaap |
Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights
ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
|
0.001 | shares |
CY2012Q3 | us-gaap |
Equity Method Investment Ownership Percentage
EquityMethodInvestmentOwnershipPercentage
|
0.44 | pure |
CY2014Q2 | dei |
Entity Public Float
EntityPublicFloat
|
4772901068 | |
CY2011Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
117997000 | |
CY2011Q4 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
70228000 | |
CY2012Q4 | us-gaap |
Accumulated Other Comprehensive Income Loss Available For Sale Securities Adjustment Net Of Tax
AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax
|
15700000 | |
CY2012Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
134053000 | |
CY2012Q4 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
51405000 | |
CY2012Q4 | alny |
Carrying Value In Equity Securities
CarryingValueInEquitySecurities
|
12400000 | |
CY2013Q4 | us-gaap |
Common Stock Shares Issued
CommonStockSharesIssued
|
63741573 | shares |
CY2013Q4 | us-gaap |
Common Stock Shares Outstanding
CommonStockSharesOutstanding
|
63741573 | shares |
CY2013Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
|
10.69 | |
CY2013Q4 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
125000000 | shares |
CY2013Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
|
22.06 | |
CY2013Q4 | us-gaap |
Preferred Stock Shares Outstanding
PreferredStockSharesOutstanding
|
0 | shares |
CY2013Q4 | us-gaap |
Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
|
0.01 | |
CY2013Q4 | us-gaap |
Preferred Stock Shares Authorized
PreferredStockSharesAuthorized
|
5000000 | shares |
CY2013Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber
|
500000 | shares |
CY2013Q4 | us-gaap |
Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
|
0.01 | |
CY2013Q4 | us-gaap |
Preferred Stock Shares Issued
PreferredStockSharesIssued
|
0 | shares |
CY2013Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
|
8245000 | shares |
CY2013Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
222393000 | |
CY2013Q4 | us-gaap |
Deferred Revenue Noncurrent
DeferredRevenueNoncurrent
|
93394000 | |
CY2013Q4 | us-gaap |
Deferred Rent Credit Current
DeferredRentCreditCurrent
|
1112000 | |
CY2013Q4 | us-gaap |
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
|
41316000 | |
CY2013Q4 | us-gaap |
Preferred Stock Value
PreferredStockValue
|
||
CY2013Q4 | us-gaap |
Liabilities Current
LiabilitiesCurrent
|
53864000 | |
CY2013Q4 | us-gaap |
Deferred Tax Liabilities Other Comprehensive Income
DeferredTaxLiabilitiesOtherComprehensiveIncome
|
13267000 | |
CY2013Q4 | us-gaap |
Common Stock Value
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|
637000 | |
CY2013Q4 | us-gaap |
Commitments And Contingencies
CommitmentsAndContingencies
|
||
CY2013Q4 | us-gaap |
Accumulated Other Comprehensive Income Loss Net Of Tax
AccumulatedOtherComprehensiveIncomeLossNetOfTax
|
19717000 | |
CY2013Q4 | us-gaap |
Accounts Payable Current
AccountsPayableCurrent
|
5896000 | |
CY2013Q4 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
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CY2013Q4 | us-gaap |
Deferred Tax Liabilities Goodwill And Intangible Assets Intangible Assets
DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets
|
7000 | |
CY2013Q4 | us-gaap |
Additional Paid In Capital Common Stock
AdditionalPaidInCapitalCommonStock
|
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CY2013Q4 | us-gaap |
Accrued Liabilities Current
AccruedLiabilitiesCurrent
|
14160000 | |
CY2013Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
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CY2013Q4 | us-gaap |
Other Accrued Liabilities Current
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|
3266000 | |
CY2013Q4 | us-gaap |
Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
|
420530000 | |
CY2013Q4 | us-gaap |
Accrued Professional Fees Current
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|
2135000 | |
CY2013Q4 | us-gaap |
Deferred Revenue Current
DeferredRevenueCurrent
|
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CY2013Q4 | us-gaap |
Liabilities
Liabilities
|
150183000 | |
CY2013Q4 | us-gaap |
Employee Related Liabilities Current
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|
4822000 | |
CY2013Q4 | us-gaap |
Deferred Rent Credit Noncurrent
DeferredRentCreditNoncurrent
|
2925000 | |
CY2013Q4 | us-gaap |
Available For Sale Securities Accumulated Gross Unrealized Gain Before Tax
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66000 | |
CY2013Q4 | us-gaap |
Cash And Cash Equivalents At Carrying Value
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|
53169000 | |
CY2013Q4 | us-gaap |
Construction In Progress Gross
ConstructionInProgressGross
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28000 | |
CY2013Q4 | us-gaap |
Furniture And Fixtures Gross
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|
1793000 | |
CY2013Q4 | us-gaap |
Property Plant And Equipment Net
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CY2013Q4 | us-gaap |
Receivables Net Current
ReceivablesNetCurrent
|
4248000 | |
CY2013Q4 | us-gaap |
Available For Sale Debt Securities Amortized Cost Basis
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297323000 | |
CY2013Q4 | us-gaap |
Deferred Tax Assets Equity Method Investments
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689000 | |
CY2013Q4 | us-gaap |
Deferred Tax Assets Goodwill And Intangible Assets
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2210000 | |
CY2013Q4 | us-gaap |
Deferred Tax Assets Gross
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|
235660000 | |
CY2013Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Foreign
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3196000 | |
CY2013Q4 | us-gaap |
Prepaid Expense And Other Assets Current
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|
3910000 | |
CY2013Q4 | us-gaap |
Deferred Tax Assets Other
DeferredTaxAssetsOther
|
4885000 | |
CY2013Q4 | us-gaap |
Available For Sale Securities Accumulated Gross Unrealized Loss Before Tax
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86000 | |
CY2013Q4 | us-gaap |
Available For Sale Securities Debt Securities Noncurrent
AvailableForSaleSecuritiesDebtSecuritiesNoncurrent
|
104602000 | |
CY2013Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Research
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23902000 | |
CY2013Q4 | us-gaap |
Deferred Tax Assets Deferred Income
DeferredTaxAssetsDeferredIncome
|
37273000 | |
CY2013Q4 | us-gaap |
Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
|
-7000 | |
CY2013Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Other
DeferredTaxAssetsTaxCreditCarryforwardsOther
|
788000 | |
CY2013Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits
|
21706000 | |
CY2013Q4 | us-gaap |
Leasehold Improvements Gross
LeaseholdImprovementsGross
|
28953000 | |
CY2013Q4 | us-gaap |
Assets Current
AssetsCurrent
|
254028000 | |
CY2013Q4 | us-gaap |
Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
|
297303000 | |
CY2013Q4 | alny |
Computer Equipment And Software Gross
ComputerEquipmentAndSoftwareGross
|
4261000 | |
CY2013Q4 | alny |
Accrued Preclinical Services Current
AccruedPreclinicalServicesCurrent
|
1004000 | |
CY2013Q4 | alny |
Accrued Clinical Trial And Manufacturing Current
AccruedClinicalTrialAndManufacturingCurrent
|
2933000 | |
CY2014Q4 | us-gaap |
Common Stock Shares Issued
CommonStockSharesIssued
|
77202753 | shares |
CY2014Q4 | us-gaap |
Common Stock Shares Outstanding
CommonStockSharesOutstanding
|
77202753 | shares |
CY2013Q4 | us-gaap |
Property Plant And Equipment Other
PropertyPlantAndEquipmentOther
|
22729000 | |
CY2013Q4 | us-gaap |
Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
|
57764000 | |
CY2013Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
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|
124797000 | |
CY2013Q4 | us-gaap |
Deferred Tax Assets In Process Research And Development
DeferredTaxAssetsInProcessResearchAndDevelopment
|
16214000 | |
CY2013Q4 | us-gaap |
Assets
Assets
|
420530000 | |
CY2013Q4 | us-gaap |
Available For Sale Securities Debt Securities Current
AvailableForSaleSecuritiesDebtSecuritiesCurrent
|
192701000 | |
CY2013Q4 | us-gaap |
Available For Sale Securities Equity Securities Noncurrent
AvailableForSaleSecuritiesEquitySecuritiesNoncurrent
|
45452000 | |
CY2014Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
|
68.02 | |
CY2014Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber
|
7292000 | shares |
CY2014Q4 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
125000000 | shares |
CY2014Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
|
33.46 | |
CY2014Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber
|
4736000 | shares |
CY2014Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice
|
21.44 | |
CY2014Q4 | us-gaap |
Equity Method Investment Ownership Percentage
EquityMethodInvestmentOwnershipPercentage
|
0.12 | pure |
CY2014Q4 | us-gaap |
Preferred Stock Shares Outstanding
PreferredStockSharesOutstanding
|
0 | shares |
CY2014Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice
|
32.53 | |
CY2014Q4 | us-gaap |
Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
|
0.01 | |
CY2014Q4 | us-gaap |
Preferred Stock Shares Authorized
PreferredStockSharesAuthorized
|
5000000 | shares |
CY2014Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber
|
30000 | shares |
CY2014Q4 | us-gaap |
Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
|
0.01 | |
CY2014Q4 | us-gaap |
Preferred Stock Shares Issued
PreferredStockSharesIssued
|
0 | shares |
CY2014Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant
ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant
|
9317147 | shares |
CY2014Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
|
7530000 | shares |
CY2014Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
268416000 | |
CY2014Q4 | us-gaap |
Deferred Revenue Noncurrent
DeferredRevenueNoncurrent
|
42983000 | |
CY2014Q4 | us-gaap |
Deferred Rent Credit Current
DeferredRentCreditCurrent
|
1005000 | |
CY2014Q4 | us-gaap |
Contractual Obligation Due In Second Year
ContractualObligationDueInSecondYear
|
724000 | |
CY2014Q4 | us-gaap |
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
|
46093000 | |
CY2014Q4 | us-gaap |
Preferred Stock Value
PreferredStockValue
|
||
CY2014Q4 | us-gaap |
Operating Leases Future Minimum Payments Due Thereafter
OperatingLeasesFutureMinimumPaymentsDueThereafter
|
13845000 | |
CY2014Q4 | us-gaap |
Liabilities Current
LiabilitiesCurrent
|
95334000 | |
CY2014Q4 | us-gaap |
Deferred Tax Liabilities Other Comprehensive Income
DeferredTaxLiabilitiesOtherComprehensiveIncome
|
32793000 | |
CY2014Q4 | us-gaap |
Deferred Tax Liabilities Current
DeferredTaxLiabilitiesCurrent
|
31667000 | |
CY2014Q4 | us-gaap |
Contractual Obligation Due In Third Year
ContractualObligationDueInThirdYear
|
744000 | |
CY2014Q4 | us-gaap |
Common Stock Value
CommonStockValue
|
772000 | |
CY2014Q4 | us-gaap |
Commitments And Contingencies
CommitmentsAndContingencies
|
||
CY2014Q4 | us-gaap |
Accumulated Other Comprehensive Income Loss Net Of Tax
AccumulatedOtherComprehensiveIncomeLossNetOfTax
|
48763000 | |
CY2014Q4 | us-gaap |
Accounts Payable Current
AccountsPayableCurrent
|
15111000 | |
CY2014Q4 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-956630000 | |
CY2014Q4 | us-gaap |
Operating Leases Future Minimum Payments Due In Four Years
OperatingLeasesFutureMinimumPaymentsDueInFourYears
|
7387000 | |
CY2014Q4 | us-gaap |
Contractual Obligation
ContractualObligation
|
18955000 | |
CY2014Q4 | us-gaap |
Additional Paid In Capital Common Stock
AdditionalPaidInCapitalCommonStock
|
1843362000 | |
CY2014Q4 | us-gaap |
Accrued Liabilities Current
AccruedLiabilitiesCurrent
|
23680000 | |
CY2014Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
936267000 | |
CY2014Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
3808000 | |
CY2014Q4 | us-gaap |
Operating Leases Future Minimum Payments Due
OperatingLeasesFutureMinimumPaymentsDue
|
50179000 | |
CY2014Q4 | us-gaap |
Operating Leases Future Minimum Payments Due In Five Years
OperatingLeasesFutureMinimumPaymentsDueInFiveYears
|
7608000 | |
CY2014Q4 | us-gaap |
Operating Leases Future Minimum Payments Due In Three Years
OperatingLeasesFutureMinimumPaymentsDueInThreeYears
|
7535000 | |
CY2014Q4 | us-gaap |
Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
|
1079595000 | |
CY2014Q4 | us-gaap |
Contractual Obligation Due In Fourth Year
ContractualObligationDueInFourthYear
|
754000 | |
CY2014Q4 | us-gaap |
Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
|
3886000 | |
CY2014Q4 | us-gaap |
Deferred Revenue Current
DeferredRevenueCurrent
|
23871000 | |
CY2014Q4 | us-gaap |
Operating Leases Future Minimum Payments Due In Two Years
OperatingLeasesFutureMinimumPaymentsDueInTwoYears
|
6994000 | |
CY2014Q4 | us-gaap |
Liabilities
Liabilities
|
143328000 | |
CY2014Q4 | us-gaap |
Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
|
7357000 | |
CY2014Q4 | us-gaap |
Deferred Rent Credit Noncurrent
DeferredRentCreditNoncurrent
|
5011000 | |
CY2014Q4 | us-gaap |
Contractual Obligation Due After Fifth Year
ContractualObligationDueAfterFifthYear
|
8592000 | |
CY2014Q4 | us-gaap |
Contractual Obligation Due In Fifth Year
ContractualObligationDueInFifthYear
|
762000 | |
CY2014Q4 | us-gaap |
Available For Sale Securities Accumulated Gross Unrealized Gain Before Tax
AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
|
28000 | |
CY2014Q4 | us-gaap |
Purchase Obligation
PurchaseObligation
|
104500000 | |
CY2014Q4 | us-gaap |
Purchase Obligation Due In Next Twelve Months
PurchaseObligationDueInNextTwelveMonths
|
59300000 | |
CY2014Q4 | us-gaap |
Operating Leases Future Minimum Payments Due Current
OperatingLeasesFutureMinimumPaymentsDueCurrent
|
6810000 | |
CY2014Q4 | us-gaap |
Contractual Obligation Due In Next Twelve Months
ContractualObligationDueInNextTwelveMonths
|
7379000 | |
CY2014Q4 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
75179000 | |
CY2014Q4 | us-gaap |
Construction In Progress Gross
ConstructionInProgressGross
|
1982000 | |
CY2014Q4 | us-gaap |
Furniture And Fixtures Gross
FurnitureAndFixturesGross
|
1999000 | |
CY2014Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
21740000 | |
CY2014Q4 | us-gaap |
Receivables Net Current
ReceivablesNetCurrent
|
39937000 | |
CY2014Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
|
478506000 | |
CY2014Q4 | us-gaap |
Available For Sale Debt Securities Amortized Cost Basis
AvailableForSaleDebtSecuritiesAmortizedCostBasis
|
807843000 | |
CY2014Q4 | us-gaap |
Deferred Tax Assets Equity Method Investments
DeferredTaxAssetsEquityMethodInvestments
|
689000 | |
CY2014Q4 | us-gaap |
Deferred Tax Assets Goodwill And Intangible Assets
DeferredTaxAssetsGoodwillAndIntangibleAssets
|
17637000 | |
CY2014Q4 | us-gaap |
Deferred Tax Assets Gross
DeferredTaxAssetsGross
|
301209000 | |
CY2014Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Aggregate Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue
|
470149000 | |
CY2014Q4 | us-gaap |
Leasehold Improvements Gross
LeaseholdImprovementsGross
|
30853000 | |
CY2014Q4 | us-gaap |
Assets Current
AssetsCurrent
|
746367000 | |
CY2014Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Foreign
DeferredTaxAssetsTaxCreditCarryforwardsForeign
|
3196000 | |
CY2014Q4 | us-gaap |
Prepaid Expense And Other Assets Current
PrepaidExpenseAndOtherAssetsCurrent
|
9739000 | |
CY2014Q4 | us-gaap |
Deferred Tax Assets Net Noncurrent
DeferredTaxAssetsNetNoncurrent
|
31667000 | |
CY2014Q4 | us-gaap |
Deferred Tax Assets Other
DeferredTaxAssetsOther
|
5871000 | |
CY2014Q4 | us-gaap |
Available For Sale Securities Accumulated Gross Unrealized Loss Before Tax
AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
|
1121000 | |
CY2014Q4 | us-gaap |
Available For Sale Securities Debt Securities Noncurrent
AvailableForSaleSecuritiesDebtSecuritiesNoncurrent
|
279821000 | |
CY2014Q4 | us-gaap |
Available For Sale Securities Equity Securities Current
AvailableForSaleSecuritiesEquitySecuritiesCurrent
|
94583000 | |
CY2014Q4 | us-gaap |
Deferred Tax Assets Deferred Income
DeferredTaxAssetsDeferredIncome
|
14273000 | |
CY2014Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Research
DeferredTaxAssetsTaxCreditCarryforwardsResearch
|
38204000 | |
CY2014Q4 | us-gaap |
Property Plant And Equipment Other
PropertyPlantAndEquipmentOther
|
28559000 | |
CY2014Q4 | us-gaap |
Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
|
67833000 | |
CY2014Q4 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1
|
357891000 | |
CY2014Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
176789000 | |
CY2014Q4 | us-gaap |
Deferred Tax Assets In Process Research And Development
DeferredTaxAssetsInProcessResearchAndDevelopment
|
19246000 | |
CY2014Q4 | us-gaap |
Assets
Assets
|
1079595000 | |
CY2014Q4 | us-gaap |
Available For Sale Securities Debt Securities Current
AvailableForSaleSecuritiesDebtSecuritiesCurrent
|
526929000 | |
CY2014Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Other
DeferredTaxAssetsTaxCreditCarryforwardsOther
|
788000 | |
CY2014Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits
|
24516000 | |
CY2014Q4 | us-gaap |
Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
|
806750000 | |
CY2014Q4 | alny |
Share Based Compensation Arrangement By Share Based Payment Award Options Vesting Percentage In Each Quarter
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestingPercentageInEachQuarter
|
0.0625 | pure |
CY2014Q4 | alny |
Purchase Obligation Thereafter
PurchaseObligationThereafter
|
45200000 | |
CY2014Q4 | alny |
Carrying Value In Equity Securities
CarryingValueInEquitySecurities
|
11900000 | |
CY2014Q4 | alny |
Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Percentage On First Anniversary
ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPercentageOnFirstAnniversary
|
0.25 | pure |
CY2014Q4 | alny |
Computer Equipment And Software Gross
ComputerEquipmentAndSoftwareGross
|
4440000 | |
CY2014Q4 | alny |
Accrued Preclinical Services Current
AccruedPreclinicalServicesCurrent
|
3081000 | |
CY2014Q4 | alny |
Accrued Clinical Trial And Manufacturing Current
AccruedClinicalTrialAndManufacturingCurrent
|
5548000 | |
CY2015Q1 | dei |
Entity Common Stock Shares Outstanding
EntityCommonStockSharesOutstanding
|
83760143 | shares |
CY2014Q1 | us-gaap |
Research And Development Asset Acquired Other Than Through Business Combination Written Off
ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff
|
199300000 | |
CY2005Q3 | alny |
Class Of Warrant Or Rights Date From Which Warrants Or Rights Expired
ClassOfWarrantOrRightsDateFromWhichWarrantsOrRightsExpired
|
2015-07-13 | |
us-gaap |
Equity Method Investment Summarized Financial Information Revenue
EquityMethodInvestmentSummarizedFinancialInformationRevenue
|
9462000 | ||
us-gaap |
Equity Method Investment Summarized Financial Information Net Income Loss
EquityMethodInvestmentSummarizedFinancialInformationNetIncomeLoss
|
-10532000 | ||
alny |
Equity Method Investment Summarized Financial Information Other Income Expense
EquityMethodInvestmentSummarizedFinancialInformationOtherIncomeExpense
|
2289000 | ||
alny |
Equity Method Investment Summarized Financial Information Operating Income Loss
EquityMethodInvestmentSummarizedFinancialInformationOperatingIncomeLoss
|
-8271000 | ||
alny |
Equity Method Investment Summarized Financial Information Income Tax Expense Benefit
EquityMethodInvestmentSummarizedFinancialInformationIncomeTaxExpenseBenefit
|
-28000 | ||
alny |
Equity Method Investment Summarized Financial Information Operating Expenses
EquityMethodInvestmentSummarizedFinancialInformationOperatingExpenses
|
17733000 | ||
CY2012Q1 | us-gaap |
Stock Issued During Period Shares New Issues
StockIssuedDuringPeriodSharesNewIssues
|
8625000 | shares |
CY2012Q1 | us-gaap |
Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
|
86800000 | |
CY2012Q1 | us-gaap |
Payments Of Stock Issuance Costs
PaymentsOfStockIssuanceCosts
|
5900000 | |
CY2012Q1 | us-gaap |
Restructuring And Related Cost Number Of Positions Eliminated Period Percent
RestructuringAndRelatedCostNumberOfPositionsEliminatedPeriodPercent
|
0.33 | pure |
CY2013Q1 | us-gaap |
Stock Issued During Period Shares New Issues
StockIssuedDuringPeriodSharesNewIssues
|
9200000 | shares |
CY2013Q1 | us-gaap |
Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
|
173600000 | |
CY2013Q1 | us-gaap |
Payments Of Stock Issuance Costs
PaymentsOfStockIssuanceCosts
|
11600000 | |
CY2009Q1 | us-gaap |
Sale Of Stock Consideration Received Per Transaction
SaleOfStockConsiderationReceivedPerTransaction
|
10000000 | |
CY2005Q3 | alny |
Tender Offer Of Voting Stock Trigger Exercisable Rights
TenderOfferOfVotingStockTriggerExercisableRights
|
0.20 | pure |
CY2005Q3 | alny |
Acquisition Of Voting Stock Trigger Exercisable Rights
AcquisitionOfVotingStockTriggerExercisableRights
|
0.50 | pure |
CY2011Q2 | us-gaap |
Stock Issued During Period Value Restricted Stock Award Gross
StockIssuedDuringPeriodValueRestrictedStockAwardGross
|
2300000 | |
CY2014Q1 | alny |
Extended Lease Expiration Date
ExtendedLeaseExpirationDate
|
2021-09-30 | |
CY2014Q1 | alny |
Lease Extension Period
LeaseExtensionPeriod
|
P5Y | |
CY2013 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Minimum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum
|
0.55 | pure |
CY2013 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
8.68 | |
CY2013 | us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
0.030 | pure |
CY2013 | us-gaap |
Effective Income Tax Rate Reconciliation Foreign Income Tax Rate Differential
EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential
|
-0.041 | pure |
CY2013 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits
EffectiveIncomeTaxRateReconciliationTaxCredits
|
0.085 | pure |
CY2010Q4 | us-gaap |
Stock Issued During Period Value Restricted Stock Award Gross
StockIssuedDuringPeriodValueRestrictedStockAwardGross
|
1400000 | |
CY2013 | us-gaap |
Income Taxes Paid Net
IncomeTaxesPaidNet
|
-11000 | |
CY2013 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Foreign
IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign
|
-10811000 | |
CY2013 | us-gaap |
Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
|
29700000 | |
CY2013 | us-gaap |
Increase Decrease In Receivables
IncreaseDecreaseInReceivables
|
4144000 | |
CY2013 | us-gaap |
Capital Expenditures Incurred But Not Yet Paid
CapitalExpendituresIncurredButNotYetPaid
|
161000 | |
CY2013 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
10229000 | |
CY2013 | us-gaap |
Increase Decrease In Deferred Revenue
IncreaseDecreaseInDeferredRevenue
|
-6201000 | |
CY2013 | us-gaap |
Operating Expenses
OperatingExpenses
|
140109000 | |
CY2013 | us-gaap |
Net Cash Provided By Used In Operating Activities Continuing Operations
NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
|
-68657000 | |
CY2013 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
|
0.00 | pure |
CY2013 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1
|
P5Y7M6D | |
CY2013 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.043 | pure |
CY2013 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
61551000 | shares |
CY2013 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
|
-0.385 | pure |
CY2013 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Minimum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum
|
0.010 | pure |
CY2013 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Other
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOther
|
-0.003 | pure |
CY2013 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-1.45 | |
CY2013 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.350 | pure |
CY2013 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Maximum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum
|
0.56 | pure |
CY2013 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Maximum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum
|
0.020 | pure |
CY2013 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
9213000 | shares |
CY2013 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
|
0.008 | pure |
CY2013 | us-gaap |
Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
|
173572000 | |
CY2013 | us-gaap |
Payments To Acquire Available For Sale Securities Debt
PaymentsToAcquireAvailableForSaleSecuritiesDebt
|
364305000 | |
CY2013 | us-gaap |
License And Services Revenue
LicenseAndServicesRevenue
|
47167000 | |
CY2013 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
1356000 | |
CY2013 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-91920000 | |
CY2013 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
27994000 | |
CY2013 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-92942000 | |
CY2013 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-85170000 | |
CY2013 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
1022000 | |
CY2013 | us-gaap |
Stock Issued During Period Value Other
StockIssuedDuringPeriodValueOther
|
1184000 | |
CY2013 | us-gaap |
Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
|
-47000 | |
CY2013 | us-gaap |
Payments For Proceeds From Tenant Allowance
PaymentsForProceedsFromTenantAllowance
|
-204000 | |
CY2013 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
4006000 | |
CY2013 | us-gaap |
Other Noncash Income Expense
OtherNoncashIncomeExpense
|
-449000 | |
CY2013 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-89225000 | |
CY2013 | us-gaap |
Investment Income Net
InvestmentIncomeNet
|
1069000 | |
CY2013 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
20703000 | |
CY2013 | us-gaap |
Payments Related To Tax Withholding For Share Based Compensation
PaymentsRelatedToTaxWithholdingForShareBasedCompensation
|
1389000 | |
CY2013 | us-gaap |
Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
|
4055000 | |
CY2013 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Domestic
IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic
|
-81109000 | |
CY2013 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
112957000 | |
CY2013 | us-gaap |
Federal Income Tax Expense Benefit Continuing Operations
FederalIncomeTaxExpenseBenefitContinuingOperations
|
-2661000 | |
CY2013 | us-gaap |
Deferred Foreign Income Tax Expense Benefit
DeferredForeignIncomeTaxExpenseBenefit
|
-34000 | |
CY2013 | us-gaap |
Income Tax Expense Benefit Intraperiod Tax Allocation
IncomeTaxExpenseBenefitIntraperiodTaxAllocation
|
-2695000 | |
CY2013 | us-gaap |
Cash And Cash Equivalents Period Increase Decrease
CashAndCashEquivalentsPeriodIncreaseDecrease
|
1764000 | |
CY2013 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
-2695000 | |
CY2013 | us-gaap |
Operating Leases Rent Expense Net
OperatingLeasesRentExpenseNet
|
4900000 | |
CY2013 | us-gaap |
Current Federal Tax Expense Benefit
CurrentFederalTaxExpenseBenefit
|
34000 | |
CY2013 | us-gaap |
Depreciation
Depreciation
|
6100000 | |
CY2013 | us-gaap |
Net Cash Provided By Used In Financing Activities Continuing Operations
NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
|
200926000 | |
CY2013 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
173572000 | |
CY2013 | us-gaap |
Adjustments Related To Tax Withholding For Share Based Compensation
AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation
|
1989000 | |
CY2013 | us-gaap |
Increase Decrease In Other Accrued Liabilities
IncreaseDecreaseInOtherAccruedLiabilities
|
1547000 | |
CY2013 | us-gaap |
Net Cash Provided By Used In Investing Activities Continuing Operations
NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
|
-130505000 | |
CY2013 | us-gaap |
Current Foreign Tax Expense Benefit
CurrentForeignTaxExpenseBenefit
|
0 | |
CY2013 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
27152000 | |
CY2013 | us-gaap |
Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
|
1832000 | |
CY2013 | us-gaap |
Proceeds From Issuance Of Shares Under Incentive And Share Based Compensation Plans Including Stock Options
ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions
|
28743000 | |
CY2013 | us-gaap |
Proceeds From Sale And Maturity Of Available For Sale Securities
ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities
|
237806000 | |
CY2013 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
20703000 | |
CY2013 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
57900000 | |
CY2013 | us-gaap |
Deferred Federal Income Tax Expense Benefit
DeferredFederalIncomeTaxExpenseBenefit
|
-2695000 | |
CY2013 | us-gaap |
Foreign Income Tax Expense Benefit Continuing Operations
ForeignIncomeTaxExpenseBenefitContinuingOperations
|
-34000 | |
CY2013 | alny |
Effective Income Tax Rate Reconciliation Deductions Orphan Drug Credit
EffectiveIncomeTaxRateReconciliationDeductionsOrphanDrugCredit
|
-0.027 | pure |
CY2013 | alny |
Lease Expiration Month And Year
LeaseExpirationMonthAndYear
|
2016-09 | |
CY2013 | alny |
Stock Repurchased To Satisfy Employees Tax Withholding
StockRepurchasedToSatisfyEmployeesTaxWithholding
|
600000 | |
CY2014 | dei |
Document Type
DocumentType
|
10-K | |
CY2014 | dei |
Entity Registrant Name
EntityRegistrantName
|
ALNYLAM PHARMACEUTICALS, INC. | |
CY2014 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeited In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod
|
0 | shares |
CY2014 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Minimum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum
|
0.53 | pure |
CY2014 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod
|
1352000 | shares |
CY2014 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1
|
P6Y2M23D | |
CY2014 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
|
14.83 | |
CY2014 | dei |
Entity Well Known Seasoned Issuer
EntityWellKnownSeasonedIssuer
|
Yes | |
CY2014 | dei |
Trading Symbol
TradingSymbol
|
ALNY | |
CY2014 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
8.68 | |
CY2014 | dei |
Entity Filer Category
EntityFilerCategory
|
Large Accelerated Filer | |
CY2014 | dei |
Entity Voluntary Filers
EntityVoluntaryFilers
|
No | |
CY2014 | us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
0.100 | pure |
CY2014 | us-gaap |
Effective Income Tax Rate Reconciliation Foreign Income Tax Rate Differential
EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential
|
-0.025 | pure |
CY2014 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits
EffectiveIncomeTaxRateReconciliationTaxCredits
|
0.035 | pure |
CY2014 | us-gaap |
Nature Of Operations
NatureOfOperations
|
<div> <table style="BORDER-COLLAPSE:COLLAPSE" border="0" cellpadding="0" cellspacing="0" width="100%"> <tr> <td width="3%" valign="top" align="left"><font style="font-family:Times New Roman" size="2"><b>1.</b></font></td> <td align="left" valign="top"><font style="font-family:Times New Roman" size="2"><b>NATURE OF BUSINESS</b></font></td> </tr> </table> <p style="margin-top:6px;margin-bottom:0px; text-indent:4%"> <font style="font-family:Times New Roman" size="2">We commenced operations on June 14, 2002 as a biopharmaceutical company seeking to develop and commercialize novel therapeutics based on RNA interference, or RNAi. We are focused on discovering, developing and commercializing RNAi therapeutics by establishing strategic alliances with leading pharmaceutical and life sciences companies, establishing and maintaining a strong intellectual property position in the RNAi field, generating revenues through licensing agreements, and ultimately developing and commercializing RNAi therapeutics for our own account. We have devoted substantially all of our efforts to business planning, research and development, acquiring, filing and expanding intellectual property rights, recruiting management and technical staff, and raising capital.</font></p> </div> | |
CY2014 | us-gaap |
Net Cash Provided By Used In Operating Activities Continuing Operations
NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
|
-165641000 | |
CY2014 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
68.28 | |
CY2014 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod
|
499000 | shares |
CY2014 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
|
0.00 | pure |
CY2014 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod
|
85000 | shares |
CY2014 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.018 | pure |
CY2014 | dei |
Document Fiscal Year Focus
DocumentFiscalYearFocus
|
2014 | |
CY2014 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod
|
29000 | shares |
CY2014 | us-gaap |
Use Of Estimates
UseOfEstimates
|
<div> <p style="MARGIN-BOTTOM: 0px; MARGIN-LEFT: 2%; MARGIN-TOP: 12px"> <font style="FONT-FAMILY: Times New Roman" size="2"><b><i>Use of Estimates</i></b></font></p> <p style="MARGIN-BOTTOM: 0px; MARGIN-TOP: 6px; TEXT-INDENT: 4%"> <font style="FONT-FAMILY: Times New Roman" size="2">The preparation of financial statements in conformity with accounting principles generally accepted in the United States of America, or GAAP, requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the date of the consolidated financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates.</font></p> </div> | |
CY2014 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
74278000 | shares |
CY2014 | dei |
Document Period End Date
DocumentPeriodEndDate
|
2014-12-31 | |
CY2014 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
|
-0.118 | pure |
CY2014 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue
|
10.59 | |
CY2014 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Minimum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum
|
0.017 | pure |
CY2014 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
|
P6Y3M26D | |
CY2014 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Expirations In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice
|
35.32 | |
CY2014 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeitures Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue
|
0 | |
CY2014 | dei |
Amendment Flag
AmendmentFlag
|
false | |
CY2014 | dei |
Current Fiscal Year End Date
CurrentFiscalYearEndDate
|
--12-31 | |
CY2014 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1
|
P4Y10M10D | |
CY2014 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
|
75.77 | |
CY2014 | dei |
Entity Central Index Key
EntityCentralIndexKey
|
0001178670 | |
CY2014 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-4.85 | |
CY2014 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.350 | pure |
CY2014 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Maximum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum
|
0.57 | pure |
CY2014 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Maximum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum
|
0.023 | pure |
CY2014 | dei |
Document Fiscal Period Focus
DocumentFiscalPeriodFocus
|
FY | |
CY2014 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
8199000 | shares |
CY2014 | us-gaap |
Concentration Risk Credit Risk
ConcentrationRiskCreditRisk
|
<div> <p style="MARGIN-BOTTOM: 0px; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: medium 'Times New Roman'; MARGIN-LEFT: 34px; MARGIN-TOP: 12px; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px"> <font style="FONT-FAMILY: 'Times New Roman'" size="2"><b><i>Concentrations of Credit Risk and Significant Customers</i></b></font></p> <p style="MARGIN-BOTTOM: 0px; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: medium 'Times New Roman'; MARGIN-TOP: 6px; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> <font style="FONT-FAMILY: 'Times New Roman'" size="2">Financial instruments that potentially expose us to concentrations of credit risk consist primarily of cash, cash equivalents and fixed income marketable securities. At December 31, 2014 and 2013, substantially all of our cash, cash equivalents and fixed income marketable securities were invested in money market mutual funds, certificates of deposit, commercial paper, corporate notes, municipal debt securities, U.S. government-sponsored enterprise securities and U.S. treasury securities through highly rated financial institutions. Investments are restricted, in accordance with our investment policy, to a concentration limit per issuer.</font></p> <p style="MARGIN-BOTTOM: 0px; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: medium 'Times New Roman'; MARGIN-TOP: 6px; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> <font style="FONT-FAMILY: 'Times New Roman'" size="2">In recent periods, our revenues from collaborations have been generated from primarily F. Hoffmann-La Roche Ltd and certain of its affiliates, collectively, Roche, which assigned its rights and obligations to Arrowhead Research Corporation, or Arrowhead, in 2011, Takeda Pharmaceutical Company Limited, or Takeda, Cubist Pharmaceuticals, Inc., or Cubist, Monsanto Company, or Monsanto, and The Medicines Company, or MDCO. For the year ended December 31, 2014, our billed and unbilled collaboration receivables were composed primarily of amounts due from Genzyme Corporation, a Sanofi company, or Genzyme, and MDCO based upon the achievement of certain milestones and, also with respect to MDCO, expense reimbursement. For the year ended December 31, 2013, our billed and unbilled collaboration receivables were composed primarily of an amount due from Genzyme based upon the initiation of a Phase 3 clinical trial.</font></p> <p style="MARGIN-BOTTOM: 0px; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 1px 'Times New Roman'; MARGIN-TOP: 6px; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px">  </p> <p style="MARGIN-BOTTOM: 0px; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: medium 'Times New Roman'; MARGIN-TOP: 0px; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> <font style="FONT-FAMILY: 'Times New Roman'" size="2">The following table summarizes customers that represent greater than 10% of our net revenues from collaborators, for the periods indicated:</font></p> <p style="MARGIN-BOTTOM: 0px; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 12px 'Times New Roman'; MARGIN-TOP: 0px; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px">  </p> <table style="FONT-FAMILY: 'Times New Roman'; BORDER-COLLAPSE: collapse; TEXT-TRANSFORM: none; WORD-SPACING: 0px; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="85%"></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="4%"></td> <td></td> <td></td> <td></td> </tr> <tr> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font size="1">  </font></td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1px solid" valign="bottom" colspan="10" align="center"><font style="FONT-FAMILY: 'Times New Roman'" size="1"><b>Year Ended<br /> December 31,</b></font></td> <td valign="bottom"><font size="1"> </font></td> </tr> <tr> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font size="1">  </font></td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1px solid" valign="bottom" colspan="2" align="center"><font style="FONT-FAMILY: 'Times New Roman'" size="1"><b>2014</b></font></td> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font size="1"> </font></td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1px solid" valign="bottom" colspan="2" align="center"><font style="FONT-FAMILY: 'Times New Roman'" size="1"><b>2013</b></font></td> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font size="1"> </font></td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1px solid" valign="bottom" colspan="2" align="center"><font style="FONT-FAMILY: 'Times New Roman'" size="1"><b>2012</b></font></td> <td valign="bottom"><font size="1"> </font></td> </tr> <tr bgcolor="#CCEEFF"> <td valign="top"> <p style="MARGIN-LEFT: 1em; TEXT-INDENT: -1em"><font style="FONT-FAMILY: 'Times New Roman'" size="2">Takeda</font></p> </td> <td valign="bottom"><font size="1">  </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">43</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">% </font></td> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">47</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">% </font></td> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">33</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">% </font></td> </tr> <tr> <td valign="top"> <p style="MARGIN-LEFT: 1em; TEXT-INDENT: -1em"><font style="FONT-FAMILY: 'Times New Roman'" size="2">Monsanto</font></p> </td> <td valign="bottom"><font size="1">  </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">30</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">% </font></td> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">12</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">% </font></td> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">*</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">  </font></td> </tr> <tr bgcolor="#CCEEFF"> <td valign="top"> <p style="MARGIN-LEFT: 1em; TEXT-INDENT: -1em"><font style="FONT-FAMILY: 'Times New Roman'" size="2">MDCO</font></p> </td> <td valign="bottom"><font size="1">  </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">21</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">% </font></td> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">*</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">  </font></td> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">*</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">  </font></td> </tr> <tr> <td valign="top"> <p style="MARGIN-LEFT: 1em; TEXT-INDENT: -1em"><font style="FONT-FAMILY: 'Times New Roman'" size="2">Cubist</font></p> </td> <td valign="bottom"><font size="1">  </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">*</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">  </font></td> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">21</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">% </font></td> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">*</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">  </font></td> </tr> <tr bgcolor="#CCEEFF"> <td valign="top"> <p style="MARGIN-LEFT: 1em; TEXT-INDENT: -1em"><font style="FONT-FAMILY: 'Times New Roman'" size="2">Roche/Arrowhead</font></p> </td> <td valign="bottom"><font size="1">  </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">*</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">  </font></td> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">*</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">  </font></td> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">56</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">% </font></td> </tr> </table> <p style="MARGIN-BOTTOM: 0px; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: medium 'Times New Roman'; MARGIN-TOP: 6px; LETTER-SPACING: normal; TEXT-INDENT: 4%; -webkit-text-stroke-width: 0px"> <font style="FONT-FAMILY: 'Times New Roman'" size="2">The following table summarizes customers with amounts due that represent greater than 10% of our billed and unbilled collaboration receivables balance, at the periods indicated:</font></p> <p style="MARGIN-BOTTOM: 0px; WHITE-SPACE: normal; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: 12px 'Times New Roman'; MARGIN-TOP: 0px; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px">  </p> <table style="FONT-FAMILY: 'Times New Roman'; BORDER-COLLAPSE: collapse; TEXT-TRANSFORM: none; WORD-SPACING: 0px; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px" cellspacing="0" cellpadding="0" width="100%" align="center" border="0"> <tr> <td width="86%"></td> <td valign="bottom" width="6%"></td> <td></td> <td></td> <td></td> <td valign="bottom" width="6%"></td> <td></td> <td></td> <td></td> </tr> <tr> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font size="1">  </font></td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1px solid" valign="bottom" colspan="6" align="center"><font style="FONT-FAMILY: 'Times New Roman'" size="1"><b>At December 31,</b></font></td> <td valign="bottom"><font size="1"> </font></td> </tr> <tr> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font size="1">  </font></td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1px solid" valign="bottom" colspan="2" align="center"><font style="FONT-FAMILY: 'Times New Roman'" size="1"><b>2014</b></font></td> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font size="1"> </font></td> <td style="BORDER-BOTTOM: rgb(0,0,0) 1px solid" valign="bottom" colspan="2" align="center"><font style="FONT-FAMILY: 'Times New Roman'" size="1"><b>2013</b></font></td> <td valign="bottom"><font size="1"> </font></td> </tr> <tr bgcolor="#CCEEFF"> <td valign="top"> <p style="MARGIN-LEFT: 1em; TEXT-INDENT: -1em"><font style="FONT-FAMILY: 'Times New Roman'" size="2">Genzyme</font></p> </td> <td valign="bottom"><font size="1">  </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">63</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">% </font></td> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">94</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">% </font></td> </tr> <tr> <td valign="top"> <p style="MARGIN-LEFT: 1em; TEXT-INDENT: -1em"><font style="FONT-FAMILY: 'Times New Roman'" size="2">MDCO</font></p> </td> <td valign="bottom"><font size="1">  </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">37</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">% </font></td> <td valign="bottom"><font size="1"> </font></td> <td valign="bottom"><font style="FONT-FAMILY: 'Times New Roman'" size="2"> </font></td> <td valign="bottom" align="right"><font style="FONT-FAMILY: 'Times New Roman'" size="2">*</font></td> <td valign="bottom" nowrap="nowrap"><font style="FONT-FAMILY: 'Times New Roman'" size="2">  </font></td> </tr> </table> <p style="MARGIN-BOTTOM: 2px; WHITE-SPACE: normal; BORDER-BOTTOM: rgb(0,0,0) 0.5pt solid; TEXT-TRANSFORM: none; WORD-SPACING: 0px; COLOR: rgb(0,0,0); FONT: medium/8px 'Times New Roman'; MARGIN-TOP: 0px; LETTER-SPACING: normal; WIDTH: 222px; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px">  </p> <table style="FONT-FAMILY: 'Times New Roman'; BORDER-COLLAPSE: collapse; TEXT-TRANSFORM: none; WORD-SPACING: 0px; LETTER-SPACING: normal; TEXT-INDENT: 0px; -webkit-text-stroke-width: 0px" cellspacing="0" cellpadding="0" width="100%" border="0"> <tr> <td valign="top" width="2%" align="left"><font style="FONT-FAMILY: 'Times New Roman'" size="2">*</font></td> <td valign="top" align="left"><font style="FONT-FAMILY: 'Times New Roman'" size="2">Represents 10% or less</font></td> </tr> </table> </div> | |
CY2014 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
|
-0.002 | pure |
CY2014 | us-gaap |
Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
|
1982000 | shares |
CY2014 | dei |
Entity Current Reporting Status
EntityCurrentReportingStatus
|
Yes | |
CY2014 | us-gaap |
Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
|
774487000 | |
CY2014 | us-gaap |
Payments To Acquire Available For Sale Securities Debt
PaymentsToAcquireAvailableForSaleSecuritiesDebt
|
977775000 | |
CY2014 | us-gaap |
Income Taxes Paid Net
IncomeTaxesPaidNet
|
517000 | |
CY2014 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Foreign
IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign
|
-28467000 | |
CY2014 | us-gaap |
Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
|
46000000 | |
CY2014 | us-gaap |
Increase Decrease In Receivables
IncreaseDecreaseInReceivables
|
35689000 | |
CY2014 | us-gaap |
Availableforsale Securities Gross Realized Gain Loss Excluding Other Than Temporary Impairments
AvailableforsaleSecuritiesGrossRealizedGainLossExcludingOtherThanTemporaryImpairments
|
2081000 | |
CY2014 | us-gaap |
License And Services Revenue
LicenseAndServicesRevenue
|
50561000 | |
CY2014 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
5829000 | |
CY2014 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-400604000 | |
CY2014 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
28449000 | |
CY2014 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-404980000 | |
CY2014 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-331349000 | |
CY2014 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
4376000 | |
CY2014 | us-gaap |
Stock Issued During Period Value Other
StockIssuedDuringPeriodValueOther
|
1581000 | |
CY2014 | us-gaap |
Stock Issued During Period Value Purchase Of Assets
StockIssuedDuringPeriodValuePurchaseOfAssets
|
195766000 | |
CY2014 | us-gaap |
Payments To Acquire Intangible Assets
PaymentsToAcquireIntangibleAssets
|
25000000 | |
CY2014 | us-gaap |
Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
|
1817000 | |
CY2014 | us-gaap |
Payments For Proceeds From Tenant Allowance
PaymentsForProceedsFromTenantAllowance
|
-1941000 | |
CY2014 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
8961000 | |
CY2014 | us-gaap |
Other Noncash Income Expense
OtherNoncashIncomeExpense
|
-692000 | |
CY2014 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-360395000 | |
CY2014 | us-gaap |
Investment Income Net
InvestmentIncomeNet
|
2559000 | |
CY2014 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
33061000 | |
CY2014 | us-gaap |
Stock Issued1
StockIssued1
|
51450000 | |
CY2014 | us-gaap |
Payments Related To Tax Withholding For Share Based Compensation
PaymentsRelatedToTaxWithholdingForShareBasedCompensation
|
15992000 | |
CY2014 | us-gaap |
Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
|
31127000 | |
CY2014 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Domestic
IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic
|
-372137000 | |
CY2014 | us-gaap |
Capital Expenditures Incurred But Not Yet Paid
CapitalExpendituresIncurredButNotYetPaid
|
1526000 | |
CY2014 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
11926000 | |
CY2014 | us-gaap |
Increase Decrease In Deferred Revenue
IncreaseDecreaseInDeferredRevenue
|
-7786000 | |
CY2014 | us-gaap |
Operating Expenses
OperatingExpenses
|
455541000 | |
CY2014 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
190249000 | |
CY2014 | us-gaap |
Federal Income Tax Expense Benefit Continuing Operations
FederalIncomeTaxExpenseBenefitContinuingOperations
|
-40209000 | |
CY2014 | us-gaap |
Income Tax Expense Benefit Intraperiod Tax Allocation
IncomeTaxExpenseBenefitIntraperiodTaxAllocation
|
-40209000 | |
CY2014 | us-gaap |
Cash And Cash Equivalents Period Increase Decrease
CashAndCashEquivalentsPeriodIncreaseDecrease
|
22010000 | |
CY2014 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
-40209000 | |
CY2014 | us-gaap |
Operating Leases Rent Expense Net
OperatingLeasesRentExpenseNet
|
8900000 | |
CY2014 | us-gaap |
Proceeds From Issuance Of Private Placement
ProceedsFromIssuanceOfPrivatePlacement
|
723037000 | |
CY2014 | us-gaap |
Depreciation
Depreciation
|
5000000 | |
CY2014 | us-gaap |
Net Cash Provided By Used In Financing Activities Continuing Operations
NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
|
736465000 | |
CY2014 | us-gaap |
Research And Development Asset Acquired Other Than Through Business Combination Written Off
ResearchAndDevelopmentAssetAcquiredOtherThanThroughBusinessCombinationWrittenOff
|
220766000 | |
CY2014 | us-gaap |
Adjustments Related To Tax Withholding For Share Based Compensation
AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation
|
15392000 | |
CY2014 | us-gaap |
Increase Decrease In Other Accrued Liabilities
IncreaseDecreaseInOtherAccruedLiabilities
|
9122000 | |
CY2014 | us-gaap |
Net Cash Provided By Used In Investing Activities Continuing Operations
NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
|
-548814000 | |
CY2014 | us-gaap |
Current Foreign Tax Expense Benefit
CurrentForeignTaxExpenseBenefit
|
0 | |
CY2014 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
44526000 | |
CY2014 | us-gaap |
Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
|
8840000 | |
CY2014 | us-gaap |
Noncash Or Part Noncash Acquisition Value Of Assets Acquired1
NoncashOrPartNoncashAcquisitionValueOfAssetsAcquired1
|
195766000 | |
CY2014 | us-gaap |
Proceeds From Issuance Of Shares Under Incentive And Share Based Compensation Plans Including Stock Options
ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions
|
29420000 | |
CY2014 | us-gaap |
Proceeds From Sale And Maturity Of Available For Sale Securities
ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities
|
462922000 | |
CY2014 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
33061000 | |
CY2014 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
126500000 | |
CY2014 | us-gaap |
Deferred Federal Income Tax Expense Benefit
DeferredFederalIncomeTaxExpenseBenefit
|
-40209000 | |
CY2014 | us-gaap |
Other Comprehensive Income Loss Reclassification Adjustment From Aoci For Sale Of Securities Net Of Tax
OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax
|
2081000 | |
CY2014 | us-gaap |
Tax Adjustments Settlements And Unusual Provisions
TaxAdjustmentsSettlementsAndUnusualProvisions
|
20683000 | |
CY2014 | alny |
Investment Maturity Period Minimum
InvestmentMaturityPeriodMinimum
|
P90D | |
CY2014 | alny |
Effective Income Tax Rate Reconciliation Deductions Orphan Drug Credit
EffectiveIncomeTaxRateReconciliationDeductionsOrphanDrugCredit
|
-0.006 | pure |
CY2012 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
50286000 | shares |
CY2012 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
|
-0.326 | pure |
CY2012 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Maximum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum
|
0.010 | pure |
CY2012 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
9536000 | shares |
CY2014 | alny |
Employee Stock Purchase Plan Offered Period
EmployeeStockPurchasePlanOfferedPeriod
|
P6M | |
CY2014 | alny |
Operating Loss Carryforward Expiration Year
OperatingLossCarryforwardExpirationYear
|
2034 | |
CY2014 | alny |
Investments Classified As Cash And Cash Equivalent Original Maturities
InvestmentsClassifiedAsCashAndCashEquivalentOriginalMaturities
|
P90D | |
CY2014 | alny |
Noncash Stock Option Exercises
NoncashStockOptionExercises
|
1219000 | |
CY2014 | alny |
Effective Income Tax Rate Reconciliation Nondeductible Expense Tax Basis In Intangible Assets
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseTaxBasisInIntangibleAssets
|
0.042 | pure |
CY2014 | alny |
Effective Income Tax Rate Reconciliation Nondeductible Expense In Process Research And Development
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseInProcessResearchAndDevelopment
|
-0.194 | pure |
CY2012 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
8.68 | |
CY2012 | us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
0.091 | pure |
CY2012 | us-gaap |
Effective Income Tax Rate Reconciliation Foreign Income Tax Rate Differential
EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential
|
-0.001 | pure |
CY2012 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits
EffectiveIncomeTaxRateReconciliationTaxCredits
|
0.042 | pure |
CY2012 | us-gaap |
Net Cash Provided By Used In Operating Activities Continuing Operations
NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
|
-115609000 | |
CY2012 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
|
0.00 | pure |
CY2012 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.049 | pure |
CY2012 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Minimum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum
|
0.008 | pure |
CY2012 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Other
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOther
|
-0.016 | pure |
CY2012 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-2.11 | |
CY2012 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.350 | pure |
CY2012 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
|
0.57 | pure |
CY2012 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
|
-0.007 | pure |
CY2012 | us-gaap |
Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
|
86800000 | |
CY2012 | us-gaap |
Stock Issued During Period Value Restricted Stock Award Net Of Forfeitures
StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures
|
-519000 | |
CY2012 | us-gaap |
Payments To Acquire Available For Sale Securities Debt
PaymentsToAcquireAvailableForSaleSecuritiesDebt
|
277129000 | |
CY2012 | us-gaap |
Increase Decrease In Restricted Cash
IncreaseDecreaseInRestrictedCash
|
162000 | |
CY2012 | us-gaap |
Income Taxes Paid Net
IncomeTaxesPaidNet
|
-17000 | |
CY2012 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Foreign
IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign
|
-186000 | |
CY2012 | us-gaap |
Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
|
38300000 | |
CY2012 | us-gaap |
Increase Decrease In Receivables
IncreaseDecreaseInReceivables
|
-1364000 | |
CY2012 | us-gaap |
Availableforsale Securities Gross Realized Gain Loss Excluding Other Than Temporary Impairments
AvailableforsaleSecuritiesGrossRealizedGainLossExcludingOtherThanTemporaryImpairments
|
255000 | |
CY2012 | us-gaap |
License And Services Revenue
LicenseAndServicesRevenue
|
66725000 | |
CY2012 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
-1780000 | |
CY2012 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-116586000 | |
CY2012 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
6402000 | |
CY2012 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-129456000 | |
CY2012 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-90187000 | |
CY2012 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
12870000 | |
CY2012 | us-gaap |
Stock Issued During Period Value Other
StockIssuedDuringPeriodValueOther
|
879000 | |
CY2012 | us-gaap |
Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
|
331000 | |
CY2012 | us-gaap |
Gain Loss On Sale Of Previously Unissued Stock By Subsidiary Or Equity Investee Nonoperating Income
GainLossOnSaleOfPreviouslyUnissuedStockBySubsidiaryOrEquityInvesteeNonoperatingIncome
|
16084000 | |
CY2012 | us-gaap |
Payments For Proceeds From Tenant Allowance
PaymentsForProceedsFromTenantAllowance
|
-1780000 | |
CY2012 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
8348000 | |
CY2012 | us-gaap |
Other Noncash Income Expense
OtherNoncashIncomeExpense
|
-364000 | |
CY2012 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-106014000 | |
CY2012 | us-gaap |
Investment Income Net
InvestmentIncomeNet
|
977000 | |
CY2012 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
12360000 | |
CY2012 | us-gaap |
Payments Related To Tax Withholding For Share Based Compensation
PaymentsRelatedToTaxWithholdingForShareBasedCompensation
|
359000 | |
CY2012 | us-gaap |
Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
|
15827000 | |
CY2012 | us-gaap |
Income Loss From Equity Method Investments
IncomeLossFromEquityMethodInvestments
|
-4522000 | |
CY2012 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Domestic
IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic
|
-116400000 | |
CY2012 | us-gaap |
Capital Expenditures Incurred But Not Yet Paid
CapitalExpendituresIncurredButNotYetPaid
|
1441000 | |
CY2012 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
9035000 | |
CY2012 | us-gaap |
Increase Decrease In Deferred Revenue
IncreaseDecreaseInDeferredRevenue
|
-8562000 | |
CY2012 | us-gaap |
Operating Expenses
OperatingExpenses
|
196181000 | |
CY2012 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
86569000 | |
CY2012 | us-gaap |
Federal Income Tax Expense Benefit Continuing Operations
FederalIncomeTaxExpenseBenefitContinuingOperations
|
-10520000 | |
CY2012 | us-gaap |
Income Tax Expense Benefit Intraperiod Tax Allocation
IncomeTaxExpenseBenefitIntraperiodTaxAllocation
|
-10572000 | |
CY2012 | us-gaap |
Cash And Cash Equivalents Period Increase Decrease
CashAndCashEquivalentsPeriodIncreaseDecrease
|
-18823000 | |
CY2012 | us-gaap |
Deferred Foreign Income Tax Expense Benefit
DeferredForeignIncomeTaxExpenseBenefit
|
-52000 | |
CY2012 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
-10572000 | |
CY2012 | us-gaap |
Operating Leases Rent Expense Net
OperatingLeasesRentExpenseNet
|
6400000 | |
CY2012 | us-gaap |
Current Federal Tax Expense Benefit
CurrentFederalTaxExpenseBenefit
|
52000 | |
CY2012 | us-gaap |
Depreciation
Depreciation
|
4600000 | |
CY2012 | us-gaap |
Net Cash Provided By Used In Financing Activities Continuing Operations
NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
|
93412000 | |
CY2012 | us-gaap |
Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodTax
|
-10600000 | |
CY2012 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
86800000 | |
CY2012 | us-gaap |
Increase Decrease In Other Accrued Liabilities
IncreaseDecreaseInOtherAccruedLiabilities
|
-3591000 | |
CY2012 | us-gaap |
Net Cash Provided By Used In Investing Activities Continuing Operations
NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
|
3374000 | |
CY2012 | us-gaap |
Current Foreign Tax Expense Benefit
CurrentForeignTaxExpenseBenefit
|
0 | |
CY2012 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
44612000 | |
CY2012 | us-gaap |
Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
|
-1736000 | |
CY2012 | us-gaap |
Proceeds From Issuance Of Shares Under Incentive And Share Based Compensation Plans Including Stock Options
ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions
|
6971000 | |
CY2012 | us-gaap |
Proceeds From Sale And Maturity Of Available For Sale Securities
ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities
|
289013000 | |
CY2012 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
12360000 | |
CY2012 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
4800000 | |
CY2012 | us-gaap |
Deferred Federal Income Tax Expense Benefit
DeferredFederalIncomeTaxExpenseBenefit
|
-10572000 | |
CY2012 | us-gaap |
Foreign Income Tax Expense Benefit Continuing Operations
ForeignIncomeTaxExpenseBenefitContinuingOperations
|
-52000 | |
CY2012 | alny |
Adjustments To Additional Paid In Capital Share Based Compensation Requisite Service Period Recognition Value For Equity Method Investee
AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationRequisiteServicePeriodRecognitionValueForEquityMethodInvestee
|
321000 | |
CY2012 | alny |
Cross License Restructuring Expense
CrossLicenseRestructuringExpense
|
65000000 | |
CY2013Q1 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
59173000 | shares |
CY2013Q1 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.15 | |
CY2013Q1 | us-gaap |
License And Services Revenue
LicenseAndServicesRevenue
|
18642000 | |
CY2013Q1 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-9013000 | |
CY2013Q1 | us-gaap |
Operating Expenses
OperatingExpenses
|
28446000 | |
CY2014Q1 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
67786000 | shares |
CY2014Q1 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-3.70 | |
CY2014Q1 | us-gaap |
License And Services Revenue
LicenseAndServicesRevenue
|
8275000 | |
CY2014Q1 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-250943000 | |
CY2014Q1 | us-gaap |
Operating Expenses
OperatingExpenses
|
277339000 | |
CY2012Q1 | us-gaap |
Restructuring Charges
RestructuringCharges
|
3900000 | |
CY2013Q2 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
61661000 | shares |
CY2013Q2 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.29 | |
CY2013Q2 | us-gaap |
License And Services Revenue
LicenseAndServicesRevenue
|
8687000 | |
CY2013Q2 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-18169000 | |
CY2013Q2 | us-gaap |
Operating Expenses
OperatingExpenses
|
29999000 | |
CY2014Q2 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
75835000 | shares |
CY2014Q2 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.58 | |
CY2014Q2 | us-gaap |
License And Services Revenue
LicenseAndServicesRevenue
|
7295000 | |
CY2014Q2 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-44074000 | |
CY2014Q2 | us-gaap |
Operating Expenses
OperatingExpenses
|
52300000 | |
CY2014Q2 | alny |
Research And Development In Process Credit
ResearchAndDevelopmentInProcessCredit
|
3900000 | |
CY2013Q3 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
62416000 | shares |
CY2013Q3 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.48 | |
CY2013Q3 | us-gaap |
License And Services Revenue
LicenseAndServicesRevenue
|
8991000 | |
CY2014Q3 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.58 | |
CY2014Q3 | us-gaap |
License And Services Revenue
LicenseAndServicesRevenue
|
10972000 | |
CY2014Q3 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-43989000 | |
CY2013Q3 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-29686000 | |
CY2013Q3 | us-gaap |
Operating Expenses
OperatingExpenses
|
41225000 | |
CY2014Q3 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
76408000 | shares |
CY2014Q3 | us-gaap |
Operating Expenses
OperatingExpenses
|
56171000 | |
CY2012Q4 | alny |
Equity Investments Other Than Equity Method Ownership Percentage
EquityInvestmentsOtherThanEquityMethodOwnershipPercentage
|
0.17 | pure |
CY2013Q4 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
62909000 | shares |
CY2013Q4 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.51 | |
CY2013Q4 | us-gaap |
License And Services Revenue
LicenseAndServicesRevenue
|
10847000 | |
CY2013Q4 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-32357000 | |
CY2013Q4 | us-gaap |
Operating Expenses
OperatingExpenses
|
40439000 | |
CY2014Q4 | us-gaap |
Weighted Average Number Of Share Outstanding Basic And Diluted
WeightedAverageNumberOfShareOutstandingBasicAndDiluted
|
76957000 | shares |
CY2014Q4 | us-gaap |
Earnings Per Share Basic And Diluted
EarningsPerShareBasicAndDiluted
|
-0.28 | |
CY2014Q4 | us-gaap |
License And Services Revenue
LicenseAndServicesRevenue
|
24019000 | |
CY2014Q4 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-21389000 | |
CY2014Q4 | us-gaap |
Operating Expenses
OperatingExpenses
|
69731000 |