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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation and amortization | |||||
| Net accretion of bond discounts/premiums | |||||
| Forgiveness of debt income | |||||
| Loss on sale of marketable securities | |||||
| Amortization of right-of-use assets | |||||
| Amortization of collaboration contract asset | |||||
| Net loss on disposal of property, equipment and leasehold improvements | |||||
| Stock-based compensation | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Other receivables | |||||
| Prepaid expenses and other assets | |||||
| Collaboration contract asset | |||||
| Accounts payable and accrued liabilities | |||||
| Operating lease liabilities | |||||
| Deferred revenue | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities: | |||||
| Purchase of marketable securities | |||||
| Maturities of marketable securities | |||||
| Sale of marketable securities | |||||
| Purchase of property, equipment and leasehold improvements | |||||
| Proceeds from disposal of property, equipment and leasehold improvements | |||||
| Net cash provided by investing activities | |||||
| Cash flows from financing activities: | |||||
| Repayments of long-term debt | |||||
| Proceeds from issuance of common stock and pre-funded warrants | |||||
| Payment of common stock offering costs | |||||
| Total payment of common stock offering costs | |||||
| Repurchase of common shares, net | |||||
| Proceeds from exercise of stock options and issuance of ESPP shares | |||||
| Net cash (used in) provided by financing activities | |||||
| Net increase (decrease) in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash, beginning of the period | |||||
| Cash, cash equivalents and restricted cash, end of the period | |||||
| Supplemental disclosure of cash flow information: | |||||
| Purchases of property, equipment and leasehold improvements unpaid at period end | |||||
| Cash paid for interest | |||||
| Cash paid for taxes | |||||
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