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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation | |||||
| Non-cash lease expense | |||||
| Commitment share expense | |||||
| Issuance costs for common stock warrant liabilities | |||||
| Loss on initial issuance of equity | |||||
| Issuance of common stock as payment of outstanding indebtedness | |||||
| Change in fair value of common stock warrant liabilities | |||||
| Change in fair value of derivative liabilities | |||||
| Change in fair value of Clene Nanomedicine contingent earn-out liability | |||||
| Change in fair value of Initial Stockholders contingent earn-out liability | |||||
| Stock-based compensation expense | |||||
| Gain on termination of lease | |||||
| Loss on sale of marketable securities | |||||
| Loss on extinguishment of notes payable | |||||
| Total loss on extinguishment of notes payable | |||||
| Loss on disposal of property and equipment | |||||
| Accretion of debt discount | |||||
| Non-cash interest expense | |||||
| Non-cash interest income on marketable securities | |||||
| Non-cash interest expense on notes payable | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Inventory | |||||
| Prepaid expenses and other current assets | |||||
| Accounts payable | |||||
| Accrued liabilities | |||||
| Operating lease obligations | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities: | |||||
| Purchases of marketable securities | |||||
| Proceeds from maturities of marketable securities | |||||
| Proceeds from sales of marketable securities | |||||
| Purchases of property and equipment | |||||
| Net cash provided by (used in) investing activities | |||||
| Cash flows from financing activities: | |||||
| Proceeds from exercise of stock options | |||||
| Proceeds from issuance of common stock, warrants, and pre-funded warrants, net of offering costs | |||||
| Proceeds from the issuance of debt and derivative liabilities | |||||
| Payments of notes payable | |||||
| Payments of notes payable modification fees | |||||
| Payments of finance lease obligations | |||||
| Proceeds from the issuance of notes payable | |||||
| Payments of notes payable issuance costs | |||||
| Net cash provided by (used in) financing activities | |||||
| Net decrease in cash, cash equivalents and restricted cash | |||||
| Cash and restricted cash - beginning of year | |||||
| Cash and restricted cash - end of year | |||||
| Cash, cash equivalents and restricted cash – beginning of period | |||||
| Cash, cash equivalents and restricted cash – end of period | |||||
| Effect of foreign exchange rate changes on cash and restricted cash | |||||
| Reconciliation of cash, cash equivalents and restricted cash to the consolidated balance sheets: | |||||
| Cash and cash equivalents | |||||
| Restricted cash | |||||
| Cash, cash equivalents and restricted cash | |||||
| Supplemental disclosure of non-cash investing and financing activities: | |||||
| Common stock warrant liability recorded upon debt modification | |||||
| Stock issued | |||||
| Payment of Outstanding Indebtedness | |||||
| Payment of Bonus Liability | |||||
| Supplemental cash flow information: | |||||
| Cash paid for interest expense | |||||
| Derivative liability recorded upon debt modification | |||||
| Derivative liability recorded upon debt issuance | |||||
| Common stock warrant liability recorded upon public stock offering | |||||
| Lease liability arising from obtaining right-of-use assets, leasehold improvements, and lease incentives | |||||
| Lease incentive realized | |||||
| Lease liability settled through termination of lease | |||||
| Reclassification of common stock warrant liability to permanent equity | |||||
| Purchases of property and equipment in accounts payable | |||||
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