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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation and amortization expense | |||||
| Depreciation expense | |||||
| Stock-based compensation expense | |||||
| Amortization of right-of-use operating lease assets | |||||
| Change in fair value of CVR liability | |||||
| Net amortization (accretion) of premiums (discounts) on marketable securities | |||||
| Loss on disposal of property and equipment | |||||
| Amortization of debt discount and issuance costs | |||||
| Loss on debt extinguishment | |||||
| Right-of-use asset impairment | |||||
| Changes in operating assets and liabilities: | |||||
| Prepaid expenses and other current assets | |||||
| Other assets | |||||
| Accounts payable | |||||
| Accrued expenses and other current liabilities | |||||
| Operating lease liability | |||||
| Other liabilities | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities: | |||||
| Purchases of property and equipment | |||||
| Purchases of marketable securities | |||||
| Maturities and sales of marketable securities | |||||
| Net cash provided by (used in) investing activities | |||||
| Cash flows from financing activities: | |||||
| Proceeds from long-term debt | |||||
| Repayment of long-term debt | |||||
| Proceeds from convertible senior notes | |||||
| Payment of debt issuance costs | |||||
| Proceeds from issuance of common stock in public offerings, net of offering costs | |||||
| IPO One Member | |||||
| IPO Two Member | |||||
| Proceeds from issuance of common stock under ATM, net of issuance costs of $4.9 million | |||||
| Proceeds from issuance of common stock and Series B non-voting convertible preferred stock in connection with the Private Placement, net of offering costs $11.7 million | |||||
| Proceeds from issuance of shares of common stock, net of offering costs of $10.7 million | |||||
| Proceeds from issuance of shares of common stock and pre-funded warrants, net of offering costs of $10.8 million | |||||
| Taxes paid related to net share settlement of equity awards | |||||
| Proceeds from issuance of common stock upon stock option exercises | |||||
| Proceeds from pre-funded warrant exercises | |||||
| Proceeds from issuance of stock from employee stock purchase plan | |||||
| Payments to CVR Holders | |||||
| Net cash provided by financing activities | |||||
| Net increase (decrease) in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash at beginning of period | |||||
| Cash, cash equivalents and restricted cash at end of period | |||||
| Supplemental disclosure of cash flow information: | |||||
| Right-of-use assets obtained in exchange for new operating lease liabilities | |||||
| Cash paid for interest | |||||
| Supplemental disclosure of noncash investing and financing information: | |||||
| Debt discount included in accrued expenses and other liabilities | |||||
| Offering costs included in accounts payable and accrued expenses | |||||
| Property & equipment included in accounts payable and accrued expenses | |||||
| Issuance of common shares in partial settlement of CVR liability | |||||
| Conversion of Series Preferred Stock into common stock | |||||
| Series A Convertible Preferred Stock | |||||
| Series B Non Voting Convertible Preferred Stock | |||||
| Total conversion of Series Preferred Stock into common stock | |||||
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