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Denali Therapeutics Inc

denalitherapeutics.com

Denali Therapeutics Inc (NASDAQ: DNLI) is a clinical-stage biopharmaceutical company focused on developing treatments for neurodegenerative diseases. The company does not generate product revenue from approved medicines; its income comes from collaboration agreements with partners including large pharmaceutical companies. Denali was founded and is headquartered in South San Francisco, California. Its pipeline targets diseases including Parkinson's disease, ALS, Alzheimer's disease, and lysosomal storage disorders, with a platform centered on its Transport Vehicle technology designed to cross the blood-brain barrier. As a pre-commercial biotechnology company, Denali funds operations primarily through collaboration and license payments rather than product sales.

Products & Services

Clinical-stage drug pipeline targeting neurodegenerative diseases including Parkinson's disease, ALS, Alzheimer's disease, and lysosomal storage disorders. Proprietary Transport Vehicle (TV) platform for blood-brain barrier drug delivery.

Revenue Model

Collaboration and license revenue from pharmaceutical partnership agreements. No approved product revenue as of the 10-K filed 2026-02-26.

Customers & Markets

Pharmaceutical company collaborators. End markets include patients with neurodegenerative diseases.

Geographic Exposure

Headquartered in South San Francisco, California. Geographic revenue mix not determinable from available filing excerpts.

Financial Snapshot

Revenue
TTM
$0.00
Gross Margin
Last 4 Quarters
N/A
Net Income
TTM
-$508.0M
Current Assets
2026 Q1
Current Liabilities
2026 Q1
Current Ratio
2026 Q1
928.46%
Total Assets
2026 Q1
Total Liabilities
2026 Q1
Book Value
2026 Q1
$926.1M
Cash
2026 Q1
P/E
Last 4 Quarters
N/A
Free Cash Flow
TTM
-$419.2M

Stock Price

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Market Cap: $4.0757 Billion

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