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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities | |||||
| Stock-based compensation expense | |||||
| Depreciation | |||||
| Noncash lease expense | |||||
| Net accretion of discounts/premiums on marketable securities | |||||
| Loss on sale of marketable securities | |||||
| Gain on disposal of property and equipment | |||||
| Changes in operating assets and liabilities | |||||
| Collaboration receivable | |||||
| Other receivables | |||||
| Prepaid expenses and other assets | |||||
| Accounts payable | |||||
| Accrued expenses and other current liabilities | |||||
| Defined benefit plan liability | |||||
| Right-of-use assets and operating lease liabilities | |||||
| Deferred revenue | |||||
| Net cash (used in) provided by operating activities | |||||
| Cash flows from investing activities: | |||||
| Purchases of property and equipment | |||||
| Proceeds from sale of property and equipment | |||||
| Purchases of marketable securities | |||||
| Proceeds from sale of marketable securities | |||||
| Proceeds from maturities of marketable securities | |||||
| Net cash used in investing activities | |||||
| Cash flows from financing activities: | |||||
| Payment of convertible preferred stock issuance costs | |||||
| Proceeds from sale of common stock pursuant to the at-the-market sales agreement, net of underwriter's discount | |||||
| At The Market Offering | |||||
| Total proceeds from sale of common stock pursuant to the at-the-market sales agreement, net of underwriter's discount | |||||
| Proceeds from underwritten public offering, net of underwriter's discount of $3,000 | |||||
| Proceeds from issuance of pre-funded warrants | |||||
| Payment of common stock and pre-funded warrant issuance costs | |||||
| Payment of pre-funded warrant issuance costs | |||||
| Proceeds from exercise of employee stock options | |||||
| Proceeds from employee stock purchase plan | |||||
| Net cash provided by financing activities | |||||
| Net (decrease) increase in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash - beginning of period | |||||
| Cash, cash equivalents and restricted cash - end of period | |||||
| Supplemental disclosure of noncash items | |||||
| Reduction of right-of-use assets for lease incentives receivable | |||||
| Purchases of property and equipment in accounts payable and accrued expenses | |||||
| Reconciliation of cash, cash equivalents and restricted cash | |||||
| Cash and cash equivalents | |||||
| Restricted cash | |||||
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