2021 Q4 Form 10-K Financial Statement
#000156459022012877 Filed on March 31, 2022
Income Statement
Concept | 2021 Q4 | 2021 Q1 | 2021 |
---|---|---|---|
Revenue | $2.440M | $1.467M | $7.300M |
YoY Change | 20.2% | -91.04% | -65.15% |
Cost Of Revenue | $2.454M | $1.480M | $7.380M |
YoY Change | 20.89% | -66.96% | -19.43% |
Gross Profit | -$14.00K | -$10.00K | -$42.00K |
YoY Change | -100.08% | -100.36% | |
Gross Profit Margin | -0.57% | -0.68% | -0.58% |
Selling, General & Admin | $4.164M | $5.410M | $18.96M |
YoY Change | -2.94% | 46.61% | 17.2% |
% of Gross Profit | |||
Research & Development | $16.14M | $17.01M | $68.89M |
YoY Change | 10.82% | 28.28% | 30.04% |
% of Gross Profit | |||
Depreciation & Amortization | $115.0K | $45.00K | $290.0K |
YoY Change | 80.0% | 110.14% | |
% of Gross Profit | |||
Operating Expenses | $20.30M | $22.43M | $68.89M |
YoY Change | 7.74% | 4.65% | 30.04% |
Operating Profit | -$20.31M | -$22.44M | -$68.93M |
YoY Change | 7.82% | 342.78% | 67.37% |
Interest Expense | -$91.00K | $17.00K | $39.00K |
YoY Change | -403.33% | -94.91% | -93.05% |
% of Operating Profit | |||
Other Income/Expense, Net | $75.00K | -$17.00K | -$87.00K |
YoY Change | -183.33% | -950.0% | -4.4% |
Pretax Income | -$20.33M | -$22.44M | -$87.93M |
YoY Change | 7.5% | 454.07% | 56.35% |
Income Tax | |||
% Of Pretax Income | |||
Net Earnings | -$20.33M | -$22.44M | -$87.90M |
YoY Change | 7.5% | 453.61% | 56.29% |
Net Earnings / Revenue | -833.16% | -1529.52% | -1204.11% |
Basic Earnings Per Share | -$2.87 | ||
Diluted Earnings Per Share | -$647.1K | -$790.4K | -$2.870M |
COMMON SHARES | |||
Basic Shares Outstanding | 30.64M | ||
Diluted Shares Outstanding | 30.64M |
Balance Sheet
Concept | 2021 Q4 | 2021 Q1 | 2021 |
---|---|---|---|
SHORT-TERM ASSETS | |||
Cash & Short-Term Investments | $46.85M | $107.0M | $46.85M |
YoY Change | -40.97% | 2.43% | -40.99% |
Cash & Equivalents | $44.35M | $83.04M | $44.35M |
Short-Term Investments | $2.500M | $24.00M | $2.504M |
Other Short-Term Assets | $2.807M | $8.500M | $2.807M |
YoY Change | -58.72% | 254.17% | -58.72% |
Inventory | |||
Prepaid Expenses | |||
Receivables | $1.818M | $1.000M | $1.818M |
Other Receivables | $0.00 | $0.00 | $0.00 |
Total Short-Term Assets | $51.48M | $116.5M | $51.48M |
YoY Change | -42.49% | 7.57% | -42.48% |
LONG-TERM ASSETS | |||
Property, Plant & Equipment | $970.0K | $2.000M | $3.714M |
YoY Change | 124.02% | -4.76% | 61.48% |
Goodwill | |||
YoY Change | |||
Intangibles | |||
YoY Change | |||
Long-Term Investments | $0.00 | $0.00 | |
YoY Change | -100.0% | -100.0% | |
Other Assets | $472.0K | $500.0K | $472.0K |
YoY Change | -10.61% | 150.0% | -5.6% |
Total Long-Term Assets | $4.186M | $2.600M | $4.186M |
YoY Change | -21.55% | 13.04% | -21.02% |
TOTAL ASSETS | |||
Total Short-Term Assets | $51.48M | $116.5M | $51.48M |
Total Long-Term Assets | $4.186M | $2.600M | $4.186M |
Total Assets | $55.66M | $119.1M | $55.66M |
YoY Change | -41.31% | 7.69% | -41.28% |
SHORT-TERM LIABILITIES | |||
YoY Change | |||
Accounts Payable | $6.419M | $3.000M | $6.419M |
YoY Change | 8.23% | 130.77% | 8.8% |
Accrued Expenses | $7.516M | $9.900M | $7.516M |
YoY Change | -24.08% | -5.71% | -24.08% |
Deferred Revenue | |||
YoY Change | |||
Short-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Long-Term Debt Due | |||
YoY Change | |||
Total Short-Term Liabilities | $14.17M | $14.20M | $14.17M |
YoY Change | -20.4% | 19.33% | -20.42% |
LONG-TERM LIABILITIES | |||
Long-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Other Long-Term Liabilities | $408.0K | $800.0K | $408.0K |
YoY Change | -59.2% | -33.33% | -59.2% |
Total Long-Term Liabilities | $408.0K | $800.0K | $408.0K |
YoY Change | -59.2% | -33.33% | -59.2% |
TOTAL LIABILITIES | |||
Total Short-Term Liabilities | $14.17M | $14.20M | $14.17M |
Total Long-Term Liabilities | $408.0K | $800.0K | $408.0K |
Total Liabilities | $14.57M | $15.00M | $14.57M |
YoY Change | -22.39% | 15.0% | -22.48% |
SHAREHOLDERS EQUITY | |||
Retained Earnings | -$402.7M | -$337.2M | |
YoY Change | 27.94% | 28.42% | |
Common Stock | $31.00K | $31.00K | |
YoY Change | 40.91% | ||
Preferred Stock | |||
YoY Change | |||
Treasury Stock (at cost) | |||
YoY Change | |||
Treasury Stock Shares | |||
Shareholders Equity | $41.09M | $104.1M | $41.09M |
YoY Change | |||
Total Liabilities & Shareholders Equity | $55.66M | $119.1M | $55.66M |
YoY Change | -41.31% | 7.7% | -41.28% |
Cashflow Statement
Concept | 2021 Q4 | 2021 Q1 | 2021 |
---|---|---|---|
OPERATING ACTIVITIES | |||
Net Income | -$20.33M | -$22.44M | -$87.90M |
YoY Change | 7.5% | 453.61% | 56.29% |
Depreciation, Depletion And Amortization | $115.0K | $45.00K | $290.0K |
YoY Change | 80.0% | 110.14% | |
Cash From Operating Activities | -$17.68M | -$24.36M | -$83.76M |
YoY Change | -20.02% | 408.48% | 52.15% |
INVESTING ACTIVITIES | |||
Capital Expenditures | $0.00 | -$839.0K | |
YoY Change | -100.0% | 179.67% | |
Acquisitions | |||
YoY Change | |||
Other Investing Activities | $2.866M | $27.60M | $49.03M |
YoY Change | -89.62% | 0.73% | 395.23% |
Cash From Investing Activities | $2.866M | $27.58M | $48.19M |
YoY Change | -89.62% | 0.66% | 398.7% |
FINANCING ACTIVITIES | |||
Cash Dividend Paid | |||
YoY Change | |||
Common Stock Issuance & Retirement, Net | $49.30M | ||
YoY Change | |||
Debt Paid & Issued, Net | |||
YoY Change | |||
Cash From Financing Activities | 0.000 | 49.46M | 49.55M |
YoY Change | 52.82% | -17.93% | |
NET CHANGE | |||
Cash From Operating Activities | -17.68M | -24.36M | -83.76M |
Cash From Investing Activities | 2.866M | 27.58M | 48.19M |
Cash From Financing Activities | 0.000 | 49.46M | 49.55M |
Net Change In Cash | -14.81M | 52.68M | 13.99M |
YoY Change | -369.27% | -4.2% | -6.7% |
FREE CASH FLOW | |||
Cash From Operating Activities | -$17.68M | -$24.36M | -$83.76M |
Capital Expenditures | $0.00 | -$839.0K | |
Free Cash Flow | -$17.68M | -$82.92M | |
YoY Change | -19.65% | 51.45% |
Facts In Submission
Frame | Concept Type | Concept / XBRL Key | Value | Unit |
---|---|---|---|---|
CY2021Q4 | us-gaap |
Commitments And Contingencies
CommitmentsAndContingencies
|
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Commitments And Contingencies
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Preferred Stock Value
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CY2020Q4 | us-gaap |
Preferred Stock Value
PreferredStockValue
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CY2021 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1
|
P6Y4M6D | |
CY2020Q4 | us-gaap |
Accrued Employee Benefits Current
AccruedEmployeeBenefitsCurrent
|
2476000 | |
CY2020Q4 | us-gaap |
Short Term Investments
ShortTermInvestments
|
48994000 | |
CY2021Q4 | us-gaap |
Accounts Receivable Net Current
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1818000 | |
CY2020Q4 | us-gaap |
Accounts Receivable Net Current
AccountsReceivableNetCurrent
|
3313000 | |
CY2020Q4 | us-gaap |
Prepaid Expense And Other Assets Current
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|
6843000 | |
CY2020Q4 | us-gaap |
Assets Current
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CY2020Q4 | us-gaap |
Long Term Investments
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CY2021Q4 | us-gaap |
Other Assets Noncurrent
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CY2020Q4 | us-gaap |
Other Assets Noncurrent
OtherAssetsNoncurrent
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528000 | |
CY2021Q4 | us-gaap |
Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
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2744000 | |
CY2020Q4 | us-gaap |
Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
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1832000 | |
CY2021Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
970000 | |
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Property Plant And Equipment Net
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433000 | |
CY2021Q4 | us-gaap |
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Assets
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55662000 | |
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Assets
Assets
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94846000 | |
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Deferred Revenue Current
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CY2020Q4 | us-gaap |
Deferred Revenue Current
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1983000 | |
CY2021Q4 | us-gaap |
Other Accrued Liabilities Current
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4072000 | |
CY2020Q4 | us-gaap |
Other Accrued Liabilities Current
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6743000 | |
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CY2020Q4 | us-gaap |
Liabilities Current
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CY2021Q4 | us-gaap |
Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
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408000 | |
CY2020Q4 | us-gaap |
Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
|
981000 | |
CY2021Q4 | us-gaap |
Liabilities
Liabilities
|
14573000 | |
CY2020Q4 | us-gaap |
Liabilities
Liabilities
|
18777000 | |
CY2021Q4 | us-gaap |
Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
|
0.001 | |
CY2020Q4 | us-gaap |
Preferred Stock Par Or Stated Value Per Share
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0.001 | |
CY2021Q4 | us-gaap |
Preferred Stock Shares Authorized
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Preferred Stock Shares Authorized
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Preferred Stock Shares Issued
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Preferred Stock Shares Issued
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Preferred Stock Shares Outstanding
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Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
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StockIssuedDuringPeriodFromESPPPurchasesAndStockOptionsExercisedValue
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CY2020Q4 | us-gaap |
Preferred Stock Shares Outstanding
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Common Stock Par Or Stated Value Per Share
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Earnings Per Share Basic And Diluted
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Stockholders Equity
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Common Stock Shares Issued
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AdditionalPaidInCapital
|
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|
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Research And Development Expense
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Net Income Loss
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15369000 | |
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Stockholders Equity
StockholdersEquity
|
41089000 | |
CY2021 | us-gaap |
Profit Loss
ProfitLoss
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Profit Loss
ProfitLoss
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Share Based Compensation
ShareBasedCompensation
|
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Share Based Compensation
ShareBasedCompensation
|
3627000 | |
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Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
290000 | |
CY2020 | us-gaap |
Depreciation Depletion And Amortization
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|
138000 | |
CY2021 | us-gaap |
Increase Decrease In Accounts Receivable
IncreaseDecreaseInAccountsReceivable
|
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CY2020 | us-gaap |
Increase Decrease In Accounts Receivable
IncreaseDecreaseInAccountsReceivable
|
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Increase Decrease In Prepaid Deferred Expense And Other Assets
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|
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Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
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CY2021 | us-gaap |
Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
|
500000 | |
CY2020 | us-gaap |
Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
|
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Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
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-3680000 | |
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Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
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Increase Decrease In Operating Lease Liability And Right Of Use Asset
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Increase Decrease In Operating Lease Liability And Right Of Use Asset
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Increase Decrease In Contract With Customer Liability
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Net Cash Provided By Used In Operating Activities
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Proceeds From Sale Maturity And Collection Of Shortterm Investments
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Payments To Acquire Investments
PaymentsToAcquireInvestments
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Payments To Acquire Investments
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Net Cash Provided By Used In Investing Activities
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|
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Net Cash Provided By Used In Investing Activities
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Proceeds From Issuance Of Common Stock For Public Offering Net Of Issuance Costs
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|
49250000 | |
CY2020 | cbio |
Proceeds From Issuance Of Common Stock For Public Offering Net Of Issuance Costs
ProceedsFromIssuanceOfCommonStockForPublicOfferingNetOfIssuanceCosts
|
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CY2021 | cbio |
Proceeds From Issuance Of Common Stock From Espp Purchases And Stock Option Exercises
ProceedsFromIssuanceOfCommonStockFromESPPPurchasesAndStockOptionExercises
|
303000 | |
CY2020 | cbio |
Proceeds From Issuance Of Common Stock From Espp Purchases And Stock Option Exercises
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435000 | |
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Net Cash Provided By Used In Financing Activities
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|
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Net Cash Provided By Used In Financing Activities
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Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
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Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
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Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
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30360000 | |
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Non Cash Or Part Non Cash Right Of Use Assets Obtained In Exchange For Operating Lease Liabilities
NonCashOrPartNonCashRightOfUseAssetsObtainedInExchangeForOperatingLeaseLiabilities
|
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Non Cash Or Part Non Cash Right Of Use Assets Obtained In Exchange For Operating Lease Liabilities
NonCashOrPartNonCashRightOfUseAssetsObtainedInExchangeForOperatingLeaseLiabilities
|
476000 | |
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Non Cash Or Part Non Cash Remeasurement Of Right Of Use Asset Due To Operating Lease Modification
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|
624000 | |
CY2021 | us-gaap |
Nature Of Operations
NatureOfOperations
|
<div style="align:left;"> <table border="0" cellpadding="0" cellspacing="0" style="border-collapse:collapse; width:100%;"> <tr> <td style="width:5.24%;white-space:nowrap" valign="top"> <p style="margin-top:12pt;margin-bottom:0pt;font-weight:bold;font-family:Times New Roman;font-size:10pt;font-style:normal;text-transform:none;font-variant: normal;"><span style="font-weight:bold;font-family:Times New Roman;font-size:10pt;font-style:normal;text-transform:none;font-variant: normal;">1.</span></p></td> <td valign="top"> <p id="NOTES_TO_CONSOLIDATED" style="margin-top:12pt;margin-bottom:0pt;font-weight:bold;font-style:normal;text-transform:none;font-variant: normal;font-family:Times New Roman;font-size:10pt;">Nature of Operations</p></td></tr></table></div> <p style="margin-top:6pt;margin-bottom:0pt;margin-left:5.24%;text-indent:0%;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">Catalyst Biosciences, Inc. and its subsidiary (the “Company” or “Catalyst”) is a <span style="color:#000000;">fully integrated research and clinical development biopharmaceutical company with expertise in protease engineering, discovery, translational research, clinical development, and manufacturing. The Company is focused on advancing its protease product candidates in the fields of hemostasis and complement regulation.</span> <span style="color:#000000;">The Company is located in South San Francisco, California and operates in</span> one segment. </p> | |
CY2021 | us-gaap |
Number Of Operating Segments
NumberOfOperatingSegments
|
1 | |
CY2021 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-87900000 | |
CY2021Q4 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-402700000 | |
CY2021Q4 | us-gaap |
Cash Cash Equivalents And Short Term Investments
CashCashEquivalentsAndShortTermInvestments
|
46900000 | |
CY2021Q4 | us-gaap |
Accounts Receivable Gross Current
AccountsReceivableGrossCurrent
|
1800000 | |
CY2021 | us-gaap |
Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
|
7300000 | |
CY2021Q4 | cbio |
Amortized Cost Available For Sale Securities
AmortizedCostAvailableForSaleSecurities
|
46851000 | |
CY2021Q4 | cbio |
Sale Securities Available
SaleSecuritiesAvailable
|
46851000 | |
CY2021Q4 | cbio |
Sale Securities Available
SaleSecuritiesAvailable
|
46851000 | |
CY2020Q4 | cbio |
Amortized Cost Available For Sale Securities
AmortizedCostAvailableForSaleSecurities
|
81892000 | |
CY2020Q4 | cbio |
Accumulated Gross Unrealized Gain Before Tax Available For Sale Securities
AccumulatedGrossUnrealizedGainBeforeTaxAvailableForSaleSecurities
|
5000 | |
CY2020Q4 | cbio |
Sale Securities Available
SaleSecuritiesAvailable
|
81897000 | |
CY2020Q4 | cbio |
Sale Securities Available
SaleSecuritiesAvailable
|
81897000 | |
CY2021 | cbio |
Gross Realized Gain Loss Net Available For Sales Securities
GrossRealizedGainLossNetAvailableForSalesSecurities
|
0 | |
CY2021Q4 | us-gaap |
Available For Sale Securities Debt Securities Current
AvailableForSaleSecuritiesDebtSecuritiesCurrent
|
2500000 | |
CY2021Q4 | cbio |
Accrued Manufacturing Expenses Current
AccruedManufacturingExpensesCurrent
|
1381000 | |
CY2020Q4 | cbio |
Accrued Manufacturing Expenses Current
AccruedManufacturingExpensesCurrent
|
2238000 | |
CY2021Q4 | cbio |
Accrued Collaboration Expenses Current
AccruedCollaborationExpensesCurrent
|
868000 | |
CY2021Q4 | cbio |
Accrued Pre Clinical Expenses Current
AccruedPreClinicalExpensesCurrent
|
773000 | |
CY2021Q4 | us-gaap |
Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
|
509000 | |
CY2021Q4 | cbio |
Accrued Clinical Expenses Current
AccruedClinicalExpensesCurrent
|
361000 | |
CY2021Q4 | cbio |
Accrued And Other Current Liabilities
AccruedAndOtherCurrentLiabilities
|
180000 | |
CY2021Q4 | us-gaap |
Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
|
P1Y3M18D | |
CY2020Q4 | us-gaap |
Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
|
P2Y3M18D | |
CY2021Q4 | us-gaap |
Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
|
0.048 | |
CY2020Q4 | us-gaap |
Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
|
0.057 | |
CY2021Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
4072000 | |
CY2020Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
6743000 | |
CY2021Q4 | cbio |
Charges Related To Write Off Of Prepaid Manufacturing Cost
ChargesRelatedToWriteOffOfPrepaidManufacturingCost
|
3800000 | |
CY2021 | us-gaap |
Lease Expiration Date1
LeaseExpirationDate1
|
2023-04-30 | |
CY2021 | cbio |
Lessee Operating Lease Renewal Term Description
LesseeOperatingLeaseRenewalTermDescription
|
no stated renewal options | |
CY2020Q3 | us-gaap |
Lessee Operating Lease Term Of Contract
LesseeOperatingLeaseTermOfContract
|
P2Y7M6D | |
CY2020Q3 | us-gaap |
Lessee Operating Lease Lease Not Yet Commenced Description
LesseeOperatingLeaseLeaseNotYetCommencedDescription
|
commenced during the fourth quarter of 2020. | |
CY2021Q4 | us-gaap |
Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
|
600000 | |
CY2021 | us-gaap |
Operating Lease Expense
OperatingLeaseExpense
|
1700000 | |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Next Twelve Months
LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
|
2044000 | |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Two
LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
|
410000 | |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
|
2454000 | |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Undiscounted Excess Amount
LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
|
69000 | |
CY2021Q4 | us-gaap |
Operating Lease Liability
OperatingLeaseLiability
|
2385000 | |
CY2020Q3 | us-gaap |
Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
|
500000 | |
CY2021 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
2603715 | |
CY2021 | cbio |
Cash Paid For Amounts Included In The Measurement Of Lease Liabilities
CashPaidForAmountsIncludedInTheMeasurementOfLeaseLiabilities
|
1641000 | |
CY2020 | cbio |
Cash Paid For Amounts Included In The Measurement Of Lease Liabilities
CashPaidForAmountsIncludedInTheMeasurementOfLeaseLiabilities
|
602000 | |
CY2021 | cbio |
Prepaid Cash Payment For Lease Liabilities
PrepaidCashPaymentForLeaseLiabilities
|
208000 | |
CY2021 | us-gaap |
Operating Lease Payments
OperatingLeasePayments
|
1849000 | |
CY2020 | us-gaap |
Operating Lease Payments
OperatingLeasePayments
|
602000 | |
CY2019Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
|
1350000 | |
CY2020 | us-gaap |
Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
|
44605 | |
CY2020 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
|
5.04 | |
CY2020 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod
|
250641 | |
CY2020 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Expirations In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod
|
17930 | |
CY2020Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
|
1337000 | |
CY2021 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
|
5.31 | |
CY2021 | us-gaap |
Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
|
5000 | |
CY2021 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
|
4.63 | |
CY2021 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice
|
6.26 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Expirations In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod
|
593 | |
CY2021 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Expirations In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice
|
566.33 | |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
|
2603630 | |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
|
7.70 | |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber
|
1513039 | |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice
|
9.37 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
4.00 | |
CY2020 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
5.20 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
3000 | |
CY2020 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
100000 | |
CY2021 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested In Period Fair Value1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1
|
2600000 | |
CY2020 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested In Period Fair Value1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1
|
3000000.0 | |
CY2021 | us-gaap |
Stock Issued During Period Shares Issued For Services
StockIssuedDuringPeriodSharesIssuedForServices
|
56912 | |
CY2020 | us-gaap |
Stock Issued During Period Shares Issued For Services
StockIssuedDuringPeriodSharesIssuedForServices
|
51056 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.2100 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.2100 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.0000 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.0000 | |
CY2021 | cbio |
Effective Income Tax Rate Reconciliation Permanent Differences
EffectiveIncomeTaxRateReconciliationPermanentDifferences
|
-0.0035 | |
CY2020 | cbio |
Effective Income Tax Rate Reconciliation Permanent Differences
EffectiveIncomeTaxRateReconciliationPermanentDifferences
|
-0.0058 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits
EffectiveIncomeTaxRateReconciliationTaxCredits
|
0.0586 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits
EffectiveIncomeTaxRateReconciliationTaxCredits
|
0.1226 | |
CY2021 | cbio |
Effective Income Tax Rate Reconciliation Derecognition
EffectiveIncomeTaxRateReconciliationDerecognition
|
0.0000 | |
CY2020 | cbio |
Effective Income Tax Rate Reconciliation Derecognition
EffectiveIncomeTaxRateReconciliationDerecognition
|
-0.4455 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
|
-0.2626 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
|
0.1225 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Other
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOther
|
-0.0025 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Other
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOther
|
-0.0038 | |
CY2021 | us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
0.0000 | |
CY2020 | us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
0.0000 | |
CY2021 | us-gaap |
Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions
UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions
|
1749000 | |
CY2021Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
4704000 | |
CY2021Q4 | us-gaap |
Income Tax Examination Penalties And Interest Accrued
IncomeTaxExaminationPenaltiesAndInterestAccrued
|
0 | |
CY2020Q4 | us-gaap |
Income Tax Examination Penalties And Interest Accrued
IncomeTaxExaminationPenaltiesAndInterestAccrued
|
0 | |
CY2021Q4 | us-gaap |
Liability For Uncertain Tax Positions Current
LiabilityForUncertainTaxPositionsCurrent
|
0 | |
CY2020Q4 | us-gaap |
Liability For Uncertain Tax Positions Current
LiabilityForUncertainTaxPositionsCurrent
|
0 | |
CY2021 | us-gaap |
Deferred Revenue Revenue Recognized1
DeferredRevenueRevenueRecognized1
|
2000000.0 | |
CY2021Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Reserves And Accruals
DeferredTaxAssetsTaxDeferredExpenseReservesAndAccruals
|
1000000 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Reserves And Accruals
DeferredTaxAssetsTaxDeferredExpenseReservesAndAccruals
|
1095000 | |
CY2021Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
47541000 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
29505000 | |
CY2021Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Research
DeferredTaxAssetsTaxCreditCarryforwardsResearch
|
12939000 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Research
DeferredTaxAssetsTaxCreditCarryforwardsResearch
|
7789000 | |
CY2021Q4 | cbio |
Deferred Tax Assets Fixed Assets And Intangibles
DeferredTaxAssetsFixedAssetsAndIntangibles
|
3000 | |
CY2020Q4 | cbio |
Deferred Tax Assets Fixed Assets And Intangibles
DeferredTaxAssetsFixedAssetsAndIntangibles
|
7000 | |
CY2021Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
61483000 | |
CY2020Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
38396000 | |
CY2021 | us-gaap |
Valuation Allowances And Reserves Period Increase Decrease
ValuationAllowancesAndReservesPeriodIncreaseDecrease
|
-23100000 | |
CY2020 | us-gaap |
Valuation Allowances And Reserves Period Increase Decrease
ValuationAllowancesAndReservesPeriodIncreaseDecrease
|
6900000 | |
CY2021 | cbio |
Research And Development Tax Credit Carry Forwards Derecognized
ResearchAndDevelopmentTaxCreditCarryForwardsDerecognized
|
15200000 | |
CY2021Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
4700000 | |
CY2020Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
3000000.0 | |
CY2019Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
1871000 | |
CY2020 | cbio |
Unrecognized Tax Benefits Increase Decrease Resulting From Prior Period Tax Positions
UnrecognizedTaxBenefitsIncreaseDecreaseResultingFromPriorPeriodTaxPositions
|
-295000 | |
CY2020 | us-gaap |
Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions
UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions
|
1379000 | |
CY2021 | us-gaap |
Interest Income Expense Nonoperating Net
InterestIncomeExpenseNonoperatingNet
|
39000 | |
CY2020 | us-gaap |
Interest Income Expense Nonoperating Net
InterestIncomeExpenseNonoperatingNet
|
561000 | |
CY2021 | cbio |
Miscellaneous Income Expense
MiscellaneousIncomeExpense
|
9000 | |
CY2020 | cbio |
Miscellaneous Income Expense
MiscellaneousIncomeExpense
|
659000 | |
CY2021 | us-gaap |
Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
|
-87000 | |
CY2020 | us-gaap |
Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
|
-91000 | |
CY2020 | cbio |
Interest And Other Income Expense Net
InterestAndOtherIncomeExpenseNet
|
1129000 | |
CY2021Q1 | cbio |
Underwriting Commissions And Offering Expenses Payable
UnderwritingCommissionsAndOfferingExpensesPayable
|
3600000 | |
CY2021Q1 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
49300000 | |
CY2021Q4 | us-gaap |
Restructuring And Related Cost Number Of Positions Eliminated Period Percent
RestructuringAndRelatedCostNumberOfPositionsEliminatedPeriodPercent
|
0.35 | |
CY2021 | us-gaap |
Severance Costs1
SeveranceCosts1
|
400000 | |
CY2020 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
2355700 | |
CY2021 | cbio |
Charges Related To Write Off Of Prepaid Manufacturing Cost
ChargesRelatedToWriteOffOfPrepaidManufacturingCost
|
3800000 | |
CY2021 | cbio |
Restructuring Liability
RestructuringLiability
|
200000 | |
CY2021 | us-gaap |
Restructuring Charges
RestructuringCharges
|
4168000 |