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$IONS
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$IONS SEC Filings

Filed On Filing
23 Oct 2026 8-K: Regulation FD Disclosure; Other Events

Ionis partner Roche announces new Phase 3 data showing sefaxersen significantly reduced proteinuria in people with IgA nephropathy (IgAN)

21 Oct 2026 8-K: Regulation FD Disclosure; Other Events

– Approval based on Phase 3 data showing unprecedented functional cure rates compared to standard of care –

19 Oct 2026 Form 4: Devers Shannon L., EVP, Chief Human Resources Ofc

Received 2,820 shares by exercise or conversion · Sold 1,357 shares ($59.1K)

19 Oct 2026 Form 4: Swayze Eric, EVP Research

Received 125 shares by exercise or conversion · Sold 53 shares ($2.31K)

16 Oct 2026 144
23 Sep 2026 8-K: Regulation FD Disclosure; Other Events

– Sefaxersen demonstrated statistically significant and clinically meaningful reductions in proteinuria versus placebo at 37 weeks, showing best-in-class potential –

04 Sep 2026 8-K: Regulation FD Disclosure; Other Events
04 Sep 2026 8-K: Regulation FD Disclosure; Other Events
02 Sep 2026 Form 4: Bennett C Frank, EVP, Chief Scientific Officer

Acquired 110 shares (Other Transaction) ($5.64K)

02 Sep 2026 Form 4: O'neil Patrick R., EVP CLO & General Counsel

Acquired 63 shares (Other Transaction) ($3.23K)

02 Sep 2026 Form 4: Monia Brett P, Director

Acquired 98 shares (Other Transaction) ($5.03K)

02 Sep 2026 Form 4: Birchler Brian, EVP, Corp and Development Ops

Acquired 58 shares (Other Transaction) ($2.98K)

31 Jul 2026 Form 4: Hayden Michael R, Director

Bought 15,000 shares ($801K) · Bought 5,000 shares ($258K)

31 Jul 2026 S-8
29 Jul 2026 IONIS PHARMACEUTICALS, INC. 10-Q 06-30-2026
29 Jul 2026 8-K: Results of Operations and Financial Condition
17 Jul 2026 Form 4: Reikes Peter N, Director

Granted 3,399 Restricted Stock Unit

17 Jul 2026 Form 4: Hantson Ludwig, Director

Granted 3,399 Restricted Stock Unit

17 Jul 2026 Form 4: Herman Joan E, Director

Received 5,220 shares by exercise or conversion

17 Jul 2026 Form 4: Berthelsen Spencer R, Director

Received 5,220 shares by exercise or conversion

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