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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operations: | |||||
| Depreciation expense | |||||
| Depreciation and amortization | |||||
| Stock-based compensation | |||||
| Change in fair value of derivative liability | |||||
| Amortization/accretion of investment securities | |||||
| Loss from initial consolidation of variable interest entity | |||||
| Non-cash lease expense | |||||
| Non-cash interest expense | |||||
| Other non-cash items | |||||
| Prepaid expenses and other current assets | |||||
| Other assets | |||||
| Accounts payable | |||||
| Accrued expenses | |||||
| Accrued external research and development expenses | |||||
| Other accrued expenses | |||||
| Operating lease liabilities | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities: | |||||
| Purchases of marketable securities | |||||
| Maturities of marketable securities | |||||
| Purchases of property and equipment | |||||
| Net cash used in investing activities | |||||
| Cash flows from financing activities: | |||||
| Proceeds from sale of common stock in underwritten offerings, net of issuance costs paid | |||||
| Proceeds from sale of pre-funded warrants in underwritten offerings, net of issuance costs paid | |||||
| Proceeds from sale of common stock in at-the-market offerings, net of issuance costs paid | |||||
| Proceeds from issuance of long-term debt, net of issuance costs paid | |||||
| Payment of debt issuance costs | |||||
| Proceeds from the issuance of common stock in pre-closing financing | |||||
| Cash acquired in connection with the reverse recapitalization | |||||
| Payment of reverse recapitalization transaction costs | |||||
| Proceeds from stock option exercises | |||||
| Contributions from employee stock purchase plan | |||||
| Net cash provided by financing activities | |||||
| Net (decrease) increase in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash, beginning of period | |||||
| Cash, cash equivalents and restricted cash, end of period | |||||
| Supplemental cash flow information | |||||
| Cash paid for income taxes | |||||
| Cash paid for interest | |||||
| Cash paid for amounts included in the measurement of operating lease liabilities | |||||
| Purchases of property and equipment included in accounts payable and accrued expenses | |||||
| Right-of-use assets obtained in exchange for new operating lease liabilities | |||||
| Net decrease in right-of-use assets related to lease modifications and reassessment events | |||||
| Net decrease in operating lease liabilities due to lease modifications and reassessment events | |||||
| Net increase (decrease) in right-of-use assets related to lease modifications and reassessment events | |||||
| Net increase (decrease) in operating lease liabilities related to lease modifications and reassessment events | |||||
| Deferred issuance costs on sale of pre-funded warrants in registered direct offering included in accounts payable and accrued expenses | |||||
| Receivable for proceeds from stock option exercises included in other current assets | |||||
| Deferred issuance costs on sale of common stock and pre-funded warrants in offerings included in accounts payable and accrued expenses | |||||
| Settlement of derivative liability upon issuance of common stock to Roche | |||||
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