$KPTI

$0.44 -$0.04 (8.82%) Live

$KPTI Overview Financial Statements SEC Filings Executives News Red Flags Capital Raising Ownership Insider Transactions Congressional Trades

Ownership

13F as of Q2 2026 · 22.7M shares outstanding

Who owns KPTI?

By type of holder

Institutions 92.9% Insiders 4.7% Everyone else 2.4%

Concentration Top 10 holders own 53.4%

Ra Capital Management, L.P. 8.5% · Adage Capital Partners GP, L.L.C. 6.7%

Institutional ownership

92.9%

+13.0 pts vs last qtr

Institutional holders

+17 vs last qtr

Net shares bought

+3.0M

by institutions in Q2 2026

New / sold out

32 / 15

positions opened vs closed

How is ownership changing?

Institutions, last 8 quarters

Biggest buyers in Q2 2026

Acorn Capital Advisors, LLC +1.2M
BlackRock, Inc. +1.2M

Biggest sellers in Q2 2026

Commodore Capital LP SOLD OUT −2.0M
T. Rowe Price Investment Management, Inc. −755.8K

Who is planning to sell?

No insider has filed a notice of proposed sale (Form 144) for Karyopharm Therapeutics Inc. in the last 12 months.

Is your stake being diluted?

Diluted share count, FY2022–FY2025

−5.2%

−1.77% a year

Each share's claim on the business

+5.5%

grew without buying or selling a share

Spent on buybacks vs paid in stock

— vs $89.6M

over 4 fiscal years

Diluted shares, split-adjusted

Buybacks Stock-based comp

How patient are the owners?

Institutional shares by how long they've been held

5+ years25% 3–5 years5% 1–3 years16% Under 1 year54%

Quarterly turnover

38.3%

of institutional shares changed hands

Top 10 managers, median time held

1.5 years

Super Investors

Investment managers reporting KPTI on Form 13F

Holder	Shares	% of company	Change vs last qtr	Held since	% of their book
CC Commodore Capital LP	—	—	SOLD OUT	—	0.0%
Shares held by quarter Peak holding2.0M (Q1'26) Change over 8 quarters0 Commodore Capital LP's full portfolio →
RC Ra Capital Management, L.P.	1.9M	8.45%	Unchanged	Q1 '26	0.2%
Shares held by quarter Peak holding1.9M (Q1'26) Change over 8 quarters+1.9M Share of the company8.450% Ra Capital Management, L.P.'s full portfolio →

Commodore Capital LP

—

% of company

—

Change vs last qtr

SOLD OUT

Held since

—

Ra Capital Management, L.P.

1.9M

% of company

8.45%

Change vs last qtr

Unchanged

Held since

Q1 '26

28 more super investors behind a free account

See every manager holding Karyopharm Therapeutics Inc., how their position has changed, and how long they've held it.

Institutional Funds

Mutual funds and ETFs reporting KPTI on Form N-PORT; together they hold 13.3% of the company

Fund	Position value	Shares	% of company	% of the fund	As of
VT Vanguard Total Stock Market Index Fund Vanguard Index Funds	$6.62M	677.7K	2.99%	0.00%	June 30, 2026
IR iShares Russell 2000 ETF iShares Trust	$4.79M	490.3K	2.16%	0.01%	June 30, 2026

Vanguard Total Stock Market Index Fund

Vanguard Index Funds

Position value

$6.62M

% of company

2.99%

% of the fund

0.00%

As of

June 30, 2026

iShares Russell 2000 ETF

iShares Trust

Position value

$4.79M

% of company

2.16%

% of the fund

0.01%

As of

June 30, 2026

23 more funds behind a free account

See every fund holding Karyopharm Therapeutics Inc. and how much of the fund the position is.

Insiders and 5%+ holders

From Forms 3/4/5 and Schedules 13D/G

Holder	Shares	% of company	Change vs last qtr	8 quarters	Held since	% of their book
PD Pakianathan Deepika Insider	337.2K	1.49%	—	—	—	—
Insider holdings come from Form 3/4/5 filings, which are not quarterly. Share of the company1.490% Pakianathan Deepika's insider activity →
PR Paulson Richard A. Insider	269.7K	1.19%	—	—	—	—
Insider holdings come from Form 3/4/5 filings, which are not quarterly. Share of the company1.190% Paulson Richard A.'s insider activity →

Pakianathan Deepika

Insider

337.2K

% of company

1.49%

Change vs last qtr

—

Held since

—

Paulson Richard A.

Insider

269.7K

% of company

1.19%

Change vs last qtr

—

Held since

—

11 more holders behind a free account

See every insider and 5%+ holder of Karyopharm Therapeutics Inc..

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