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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Operating Activities | |||||
| Net income | |||||
| Adjustments to reconcile net income to net cash used in operating activities | |||||
| Gain from sale of priority review voucher | |||||
| Deferred tax asset | |||||
| Depreciation | |||||
| (Accretion) amortization | |||||
| Accretion of marketable securities | |||||
| Amortization of operating lease right-of-use assets | |||||
| Stock-based compensation expense, net | |||||
| Loss on disposal of fixed assets | |||||
| Non-cash interest expense | |||||
| Realized gain on investments | |||||
| Other, net | |||||
| Changes in operating assets and liabilities | |||||
| Accounts receivable, net | |||||
| Inventory | |||||
| Prepaid taxes | |||||
| Prepaid expenses and other assets | |||||
| Other non-current assets | |||||
| Lease liability | |||||
| Other long-term liabilities | |||||
| Accounts payable | |||||
| Accrued rebates | |||||
| Accrued expenses and other current liabilities | |||||
| Accrued legal settlement | |||||
| Net cash provided by (used in) operating activities | |||||
| Investing Activities | |||||
| Proceeds from disposal of assets | |||||
| Proceeds from sale of priority review voucher | |||||
| Purchases of property and equipment | |||||
| Purchases of investments | |||||
| Maturities of investments | |||||
| Net cash (used in) provided by investing activities | |||||
| Financing Activities | |||||
| Proceeds from issuance of common stock, net | |||||
| Proceeds from exercise of stock options | |||||
| Taxes paid for employee tax withholding related to restricted stock units and Taxes paid related to settlement of restricted stock awards | |||||
| Restricted Stock Units (RSUs) | |||||
| Restricted Stock | |||||
| Total taxes paid for employee tax withholding related to restricted stock units and Taxes paid related to settlement of restricted stock awards | |||||
| Repayment of ASTRA build-to-suit liability | |||||
| Net cash provided by financing activities | |||||
| Effect of exchange rate changes on cash and cash equivalents | |||||
| Net change in cash and cash equivalents | |||||
| Cash and cash equivalents at beginning of year | |||||
| Cash and cash equivalents at end of year | |||||
| Supplemental Disclosures of Non-Cash Investing and Financing Activities | |||||
| Unpaid purchases of property and equipment | |||||
| Initial recognition of right-of-use assets | |||||
| Supplemental Disclosure of Cash Flow Information | |||||
| Income taxes paid | |||||
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